Below are several figures from our
analysis of SNP data being gathered by the Nickerson lab for the PGA
study. This data consists of 24 African-American (AA) subjects and 23
European (CEPH) subjects. A table is
available listing length sequenced for each gene and the number of SNPs
found, nucleotide diversity and Tajima's D within each population and
overall for each gene.
Figure 1. Number of SNPs for different frequency ranges. Solid
bars show the number of SNPs that are common to both populations; hashed
bars show the number of SNPs that are found only in one population.
Figure 2. Same as in Figure 1 except just for the African American
Figure 3. Same as in Figure 1 except just for the European
Figure 4. Frequency distribution for the African American
(red) and European (blue) populations binned in 10% bins. The black
line indicates the expected distribution under a neutral constant
Figure 5. Same as shown in Figure 4 except the number of SNPs
within each frequency range are plotted rather than the percentage within
each frequency range.
Figure 6. Nucleotide diversity for the African American
(red) and European (blue) populations within each gene. Dashed lines
indicate the average values within each population.