SLCO1B1 Color FASTA
The longest form of insertion/deletion sites is shown in the FASTA sequence and contain a '-' as the alternate allele in the variation tag.
*Display courtesy of
GeneSNPs
TAATTAGGTG TTGAATCTAT A
A
T
G
T
G
C
C
A
G
G
C
A
T
T
A
T
G
T
A
A
G
G
C
A
C
T
T
T
A
50 |
REPEAT
C
A
T
A
C
A
C
T
A
A
A
T
C
T
T
T
A
T
T
C
C
A
A
A
T
A
T
A
G
A
C
T
T
C
T
T
A
C
T
T
T
A
T
A
G
A
T
G
A
G
100 |
var(61):[C:0.07]
T
G
C
A
C
T
G
A
T
G
C
T
C
A
G
A
A
A
T
G
G
T
A
A
A
T
A
A
C
C
T
A
C
T
G
A
T
G
T
T
T
A
T
A
C
T
G
C
T
G
150
G
C
A
G
G
T
A
G
C
A
G
A
G
A
C
A
T
A
T
C
G
G
C
A
T
T
T
A
A
G
T
C
T
T
T
C
A
G
A
C
T
T
C
A
A
A
G
G
C
C
200
A
T
G
ATATTTC ATCAGAGCTG TGATAGCCGT TCCTGAAAAA AATATCAGCT
250 |
var(201):[G:0.03]
GATTCTTTAA ATCAATTTTT GTCATCTAAC TGATGCGTGG CTGTTAGCAT
300
AATATTGATC TTGAAAGATG TTTTGCAACA TCTTTCCCCT GGTGTACTCT
350
TGTTTTTCCA
T
GATCCCACA AAATGAGCAG TCTAATTATT TACACAATTA
400 |
var(361):[C:0.17]
GGAAGAGAAA AGGGGCACAG AGAATGCTCT TTGACCTCTG AAAATATTGG
450
AGAATTTTAC AACTGGCACC TTTAGCTCAG GATTATAAAG GTTGTTAGTT
500
AGTTTGTACT GTTTTATCTT CATTGTATAT AATATATATA TTAGTCTCCA
550
AACATGTTGA TGTGTTTTCA ATGAAATGGA TGTCTGAGGA GAAAACCATT
600
AGCCTGAGAA AACCCAAACT GTATTCCCAT TGTGAATAAA AGGAAGTCCA
650
TAAAAATGAT GGAAAATGTT CTGCATTCCT GTTATGATAT CAAAATCTG
G
700 |
REPEAT
C
A
G
T
A
C
A
T
G
A
A
A
A
T
T
T
T
T
C
A
A
A
G
T
G
C
T
T
A
T
T
T
A
A
C
A
G
G
C
A
T
A
A
T
C
T
T
T
G
G
750 |
var(704):[A:0.01]
|
var(729):[T:0.06]
|
var(744):[G:0.05]
T
C
T
C
C
T
G
A
G
C
C
A
G
A
A
T
C
T
G
C
T
G
G
G
T
A
T
G
G
G
A
C
T
G
G
A
T
T
G
C
T
A
T
T
T
T
G
A
C
A
800
A
C
T
C
G
C
C
A
G
T
A
G
A
T
T
C
T
TAC TCAGCAGAGT ATTTGGAAGC CTTACTCTAA
850
TATTTTGGCC TTGGGTCTAC ATTTCTCAGT TCTGCACAGT CATTCTTCCC
900
CTCTACACTA CTCTTTAGTT TGTCTCATGA TTCCAATACT CTCAATAATT
950
AACCAAGAAT AGAACTAATC AATCAGATAA CTGTGGCACA GACATCAAAT
1000
ACATTTTGCT GCAACCATAT CAACAAATGT CCCATGAATG
A
TAAGGGGTA
1050 |
var(1041):[G:0.04]
ACCATATTCT CATATATGCA TCCTCACATT ACCACATATA TATATGTGCA
1100
TATGTGTATA CA
G
GTAAAAG TGTGTATATA TGTATACATG TATGTTTGTG
1150 |
var(1113):[A:0.03]
TGTATATACA TACATATATC TTCACACTTT TCTGAAATA
T
ATATATTTAT
1200 |
var(1190):[G:0.02]
GTGAGAGAAG GGTCTGTACT TTATTTCAGA AGAGAGCTTA ATGTCCAAGG
1250
TATAATTGAG AGTCTAAAAT GTTTGAGTTA TTGAATTAAT TAAACTTCAT
1300
CTCTACTCAA GAAAACTTTT AACTGAGTTA AGCTCTTCCT TTCTCCACAA
1350
GTCAAGTCAA TAAAAGGAAA CTGTGATATT AATAATTCTT TCCTGTTTTG
1400
ATGTAAAGAA TCTATCGCAT AAAGCAGTCT TAATTTTCAT CATTCAGAAA
1450
AATGGTCTTG CAGTTAATTG GGACTCTCTT ATTCCA
G
GTG GTATCTCCAG
1500 |
var(1487):[A:0.01]
TCTCCATACA TACCACGTTA GAACCATACT TATGTACCAA GCAAAGAGGG
1550
TATATTTTAA TTTTTAAATG CCAATGTAAC CTGTAGGCAT ATTTTTTATT
1600
TGTCTTAAA
T
TATTTCCTAT TTGGAAGTTT TAAATACCTG GAATAATTTA
1650 |
var(1610):[C:0.10]
TTGTACTCAT ATTTTTAAAG AAAAAAATCT TATGCCACCA ACTTAATTGA
1700
ATAAACAAGT AAAAGCCATT CCCAAAAGTA AGGTTTACTT GTTAAGATTA
1750
ACAAAAAATA ATGTGAGAAT TCTGAGAAAT ATAATCTTTA AATATTGGCA
1800
ACTGGAGTGA ACTCTTAAAA CTAACTAGGT TTTATATGTT TGACTAGAGC
1850
AATGACATAA TAAGGTGGTT AATCATCACT GGACTTGTTT TCAAAAAGCC
1900
AACTACTTTA AGAGGAATAA AGGGTG
G
A
C
T
T
G
T
T
G
C
A
G
T
T
G
C
T
G
T
A
G
G
A
T
1950 | Exon 1 |
UTR
T
C
T
A
A
A
T
C
C
A
G
GTAAGAACC ATTGAGATTC TCTAATTTTT ACATATATTT
2000
TATGTAAGAA ATTTTCACGG AAGAAGATTT TGATGGTCTT GAAAAATATT
2050
ACGAATTTTA TGCTCTGTGT CTTCCACACG CTTACATTCT GAGCCCTTAA
2100
AACATAGTAA ATATTCCTTC TGGGAGTAGA AGAGCC
T
CAG GTTTATATAC
2150 |
var(2137):[G:0.02]
TGTTAAAAAT AAAGTAGAGA AAATAATACC TTTATATATT TAAATATAAA
2200
GTTTCAAATC TTGGTCTTAT TAATTTCCAA ACAAATAAAA ATCAAGTCTC
2250
AAAAATGAAG CTCTAGTTAC CTTCTTAAAA TATGCTACAG GATAATTATT
2300
TTTGTCAACT ACATTGACTG ATCACACTAG ACTCCTTATT TCTTTGATGT
2350
CTTCTTAACT GGATGAAGGC AGCCAAGGGT GGGAGTAGAG GGAAGAGTTA
2400
ATTGGCAAAC ATAAAAAACA GGTGTCTCAA
A
G
T
C
A
C
A
T
A
A
C
C
A
C
C
T
C
A
G
T
2450 |
NOT SCANNED
T
T
C
C
T
T
G
T
T
T
C
A
A
C
T
C
A
A
G
T
T
T
G
A
T
A
C
A
G
G
G
T
G
A
A
G
G
G
A
A
A
T
A
T
A
T
T
T
T
C
2500
T
A
G
A
T
A
A
T
T
T
A
T
C
T
C
C
A
A
T
T
A
A
A
T
A
A
G
C
A
A
A
A
A
G
T
C
T
T
C
T
C
A
G
T
A
C
A
G
T
T
2550
T
T
T
T
T
C
T
T
T
T
T
T
T
A
T
T
T
C
A
T
T
A
T
T
A
T
T
A
T
A
C
T
T
T
A
A
G
T
T
T
T
A
G
G
G
T
A
C
A
T
2600 |
REPEAT
G
T
G
C
A
C
A
A
C
A
T
G
C
A
G
G
T
T
T
G
T
T
A
C
A
T
A
T
G
T
A
T
A
C
A
T
G
T
G
C
C
A
T
G
T
T
G
G
T
G
2650
T
G
C
T
G
C
A
C
C
C
A
T
T
A
A
C
T
C
A
T
C
A
T
T
T
A
A
C
A
T
T
G
G
G
C
A
T
A
T
C
T
C
C
T
A
A
T
G
C
T
2700
A
T
C
C
C
T
C
C
C
C
T
C
T
C
C
C
C
C
A
C
C
C
C
A
C
A
A
C
A
G
T
C
C
C
C
G
G
T
G
T
G
T
G
A
T
G
T
T
C
C
2750
C
T
T
T
C
C
T
G
T
G
T
C
C
A
T
G
T
G
T
T
C
T
C
A
T
T
G
T
T
C
A
G
T
T
C
C
C
A
C
C
T
A
T
G
A
G
T
G
A
G
2800
A
A
C
A
T
G
C
G
G
T
G
T
T
T
G
G
T
T
T
T
T
T
G
T
C
C
T
T
G
C
G
A
T
A
G
T
T
T
G
T
T
G
A
G
A
A
T
G
A
T
2850
G
G
T
T
T
C
C
A
G
T
T
T
C
A
T
C
C
A
T
G
T
C
C
C
T
A
C
A
A
A
G
G
A
C
A
T
A
A
A
C
T
C
A
T
C
A
T
T
T
T
2900
T
A
T
G
G
C
T
G
C
A
T
A
G
T
A
T
T
C
C
A
T
G
G
T
G
T
A
T
G
T
G
T
G
C
C
A
C
A
T
T
T
T
C
T
T
A
A
T
C
C
2950
A
C
T
C
T
A
T
C
G
T
T
G
T
T
G
G
A
C
A
T
T
T
A
G
G
T
T
G
G
T
T
C
C
A
A
G
T
C
T
T
T
G
C
T
A
C
T
G
T
G
3000
A
A
T
A
G
T
G
C
C
G
C
T
A
T
A
A
A
C
A
T
A
C
G
T
G
T
G
C
A
T
G
T
G
T
C
T
T
T
A
T
A
G
C
A
G
C
A
T
G
A
3050
T
T
T
A
T
A
A
T
C
C
C
T
T
G
G
G
T
A
T
A
T
A
T
C
C
A
C
T
T
A
T
G
G
G
A
T
G
G
C
T
G
G
G
T
C
A
A
A
T
G
3100
G
T
A
T
T
T
C
C
A
G
T
T
C
T
A
G
A
T
C
C
C
T
G
A
G
G
A
A
T
C
G
C
C
A
C
A
C
T
G
T
C
T
T
C
C
A
C
A
A
T
3150
G
G
T
T
G
A
A
C
T
A
G
T
T
T
A
C
A
G
T
C
C
C
A
C
C
A
A
C
A
G
T
G
T
A
A
A
A
G
T
G
T
T
C
C
T
A
T
T
T
C
3200
T
C
C
A
C
A
T
C
C
T
C
T
C
C
A
G
C
A
C
C
T
G
T
T
G
T
T
T
C
C
T
G
A
C
T
T
T
T
T
A
A
T
G
A
T
C
G
C
T
A
3250
T
T
C
T
A
A
C
T
G
G
T
G
T
G
A
G
A
T
A
G
T
A
T
C
T
C
A
T
T
G
T
G
G
T
T
T
T
G
A
T
T
T
G
C
A
T
T
T
C
T
3300
C
T
G
A
T
G
G
C
C
A
G
T
G
A
T
G
A
T
G
A
G
C
A
T
T
T
T
T
T
C
A
C
G
T
G
T
T
T
T
T
T
G
G
C
T
G
C
A
T
A
3350
A
A
T
G
T
C
T
T
C
T
G
T
T
G
A
G
A
A
G
T
G
T
C
T
G
T
T
C
A
T
G
T
C
C
T
T
C
A
C
C
C
A
C
T
T
C
T
T
G
A
3400
T
G
G
G
G
T
C
G
T
T
T
G
T
C
T
T
T
T
G
T
A
A
A
T
T
T
G
T
T
T
G
A
G
T
T
C
A
T
T
G
T
A
G
A
T
T
T
T
G
G
3450
G
T
A
T
T
A
G
C
C
T
T
T
T
G
T
C
A
G
A
T
G
A
G
T
A
G
G
T
T
G
C
A
A
A
A
A
T
T
T
T
C
T
C
C
C
A
T
T
C
T
3500
G
T
A
G
G
T
T
G
C
C
T
G
T
T
C
A
C
T
C
T
G
A
T
G
G
T
A
G
T
T
T
C
T
T
T
T
G
C
T
G
T
G
C
A
G
A
A
G
C
T
3550
C
T
T
T
A
G
T
T
T
A
A
T
T
A
T
A
T
C
T
C
A
T
T
T
G
T
C
A
T
T
T
T
T
G
G
C
T
T
T
T
G
T
T
G
C
C
A
T
T
G
3600
C
T
T
T
T
G
G
T
G
T
T
T
T
A
G
A
C
A
T
G
A
A
G
T
C
C
T
T
G
C
C
C
A
T
G
C
C
T
A
T
G
T
C
C
T
G
A
A
T
G
3650
G
T
A
T
T
G
C
C
T
A
G
G
T
T
T
T
C
T
T
C
T
A
G
G
G
T
T
T
T
T
A
T
G
G
T
T
T
T
A
G
G
T
C
T
A
A
C
A
T
T
3700
T
A
A
G
T
C
T
T
T
A
A
T
C
C
A
T
C
T
T
G
A
A
T
T
A
A
T
T
T
T
T
G
T
G
T
A
A
G
G
T
G
T
A
A
G
G
A
A
G
G
3750
G
A
T
C
C
A
G
T
T
T
C
A
G
C
T
T
T
C
T
A
C
A
T
A
T
G
G
C
T
T
G
C
C
A
G
T
T
T
T
C
C
C
A
G
C
A
T
C
A
T
3800
T
T
A
T
T
A
A
A
T
A
G
G
G
A
A
T
C
C
T
T
T
C
C
C
C
A
T
T
G
C
T
T
G
T
T
T
T
T
C
T
C
A
G
G
T
T
T
G
T
C
3850
A
A
A
G
A
T
C
A
G
A
T
A
G
T
T
G
T
A
G
A
T
A
T
G
C
G
G
C
A
C
T
A
T
T
T
C
T
G
A
G
G
G
C
T
C
T
G
T
T
C
3900
T
G
T
T
C
C
A
T
T
G
G
T
C
T
A
T
A
T
C
T
C
T
G
T
T
T
T
G
G
T
A
C
C
A
G
T
A
C
C
A
T
G
C
T
G
T
T
T
T
G
3950
G
T
T
A
C
T
G
T
A
G
C
C
T
T
G
T
A
G
T
A
T
A
G
T
T
T
G
A
A
G
T
C
A
G
G
T
A
G
G
G
T
G
A
T
G
C
C
T
C
C
4000
A
G
C
T
T
T
G
T
T
C
T
T
T
T
C
G
C
T
T
A
G
G
A
T
T
G
A
C
T
T
G
G
T
A
T
G
C
G
G
G
C
T
C
T
T
T
T
T
T
G
4050
G
T
T
C
C
A
T
A
T
G
A
A
C
T
T
T
A
A
A
G
T
A
G
T
T
T
T
T
T
C
C
A
A
T
T
C
T
G
T
G
A
A
G
A
A
A
G
T
C
A
4100
T
T
G
G
T
A
G
C
T
T
G
A
T
G
G
G
G
A
T
G
G
C
A
T
T
G
A
A
T
C
T
A
T
A
A
A
T
T
A
C
C
T
T
G
G
A
C
A
G
T
4150
A
T
G
G
C
C
A
T
T
T
T
C
A
T
G
A
T
A
T
T
G
A
T
T
C
T
T
C
C
T
G
C
C
C
A
T
G
A
G
C
A
T
G
G
A
A
T
G
T
T
4200
C
T
T
C
T
A
T
T
T
G
T
T
C
G
T
A
T
C
C
T
C
T
T
T
T
A
T
T
T
C
A
T
T
G
A
G
C
A
G
T
G
G
T
T
T
G
T
A
G
T
4250
T
C
T
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T
G
C
C
G
A
G
A
G
A
T
C
A
G
C
T
G
T
T
A
G
T
C
T
G
A
T
G
G
G
C
T
T
C
C
C
T
T
T
6950
G
T
G
G
G
T
A
A
C
C
C
A
A
C
C
T
T
T
C
T
C
T
C
T
G
G
C
T
G
C
C
C
T
T
A
A
T
A
T
T
T
T
T
T
C
C
T
T
C
A
7000
T
T
T
C
A
A
C
T
T
T
G
G
T
G
A
A
T
C
T
G
A
C
A
A
T
T
A
T
G
T
G
T
C
T
T
G
G
A
G
T
T
G
C
T
C
T
T
C
T
C
7050
G
A
G
G
A
G
T
A
T
C
T
T
T
G
T
G
G
C
G
T
A
C
T
C
T
G
T
A
T
T
T
C
C
T
G
A
A
T
C
T
G
A
A
C
G
T
T
G
G
C
7100
C
T
G
C
C
T
T
G
C
T
A
G
A
T
T
G
G
G
G
A
A
G
T
T
C
T
C
C
T
G
G
A
T
A
A
T
A
T
C
C
T
G
C
A
G
A
G
T
G
T
7150
T
T
T
C
C
A
A
C
T
T
G
G
T
T
C
C
C
T
T
C
T
C
C
C
C
A
T
C
A
C
T
T
T
C
A
G
G
T
A
C
A
C
C
A
A
T
C
A
G
A
7200
C
G
T
A
G
A
T
T
T
G
G
T
C
T
T
T
T
C
A
C
A
T
A
G
T
C
C
C
A
T
A
T
T
T
C
T
T
G
G
A
G
G
C
T
T
T
G
T
T
C
7250
G
T
T
T
C
T
T
T
T
T
A
T
T
C
T
T
T
T
T
T
C
T
C
T
A
A
A
C
T
T
C
T
C
T
T
C
T
C
A
C
T
T
C
A
T
T
T
C
A
T
7300
T
C
A
T
T
T
C
G
T
C
T
T
C
C
A
T
C
A
C
T
G
A
T
A
A
C
C
T
T
T
C
T
T
C
C
A
G
T
T
G
A
T
C
C
T
A
T
C
A
G
7350
C
T
A
C
T
G
A
G
G
C
T
T
C
T
G
C
A
T
T
T
G
T
C
A
T
G
T
G
G
C
T
C
T
C
T
T
G
C
C
T
T
G
G
T
T
T
T
C
A
G
7400
C
T
C
C
A
T
C
A
A
G
T
C
C
T
T
T
A
A
G
A
A
C
T
T
C
T
C
T
G
C
A
T
T
G
G
T
T
A
T
T
C
T
A
G
T
T
A
T
C
C
7450
A
T
T
T
G
T
C
T
G
A
T
T
T
T
T
T
T
T
C
A
A
A
G
C
T
T
T
T
A
A
C
T
T
C
T
T
T
G
C
C
A
T
T
G
G
T
T
T
G
A
7500
A
T
T
T
C
C
A
C
C
T
G
T
A
G
C
T
C
A
G
A
G
T
A
G
T
T
T
G
A
T
C
A
T
C
T
G
A
A
G
C
C
T
T
C
T
T
C
T
C
T
7550
C
A
A
C
T
T
G
T
C
A
A
A
G
T
C
A
T
T
C
T
C
C
A
T
C
C
A
G
C
T
T
T
G
T
T
C
C
G
T
T
G
C
T
G
G
T
G
A
G
G
7600
A
G
C
T
G
C
A
T
T
C
C
T
T
T
G
G
A
G
G
A
G
G
A
G
A
G
G
C
G
C
T
C
T
G
A
T
C
T
T
T
A
G
A
G
T
T
T
C
C
A
7650
G
T
T
T
T
T
C
T
G
C
T
C
T
G
T
T
T
T
T
T
T
C
T
C
A
T
C
T
T
T
G
T
G
G
T
T
T
C
A
T
C
T
A
T
C
T
T
T
G
G
7700
T
C
T
T
T
G
A
T
G
A
T
G
G
T
G
A
C
G
T
A
C
A
G
A
T
G
G
G
T
T
T
T
T
G
G
T
G
C
G
G
A
T
G
T
C
C
T
T
T
C
7750
T
G
T
T
T
G
T
T
A
G
T
T
T
T
C
C
T
T
C
T
A
A
C
A
G
A
C
A
G
G
A
C
C
C
T
C
A
G
C
T
G
C
A
G
G
T
C
T
G
T
7800
T
A
G
A
G
T
T
T
G
C
T
A
G
A
G
G
T
C
C
A
C
T
G
C
A
G
A
C
C
C
T
G
T
T
T
G
C
C
T
G
G
G
T
T
T
C
A
G
C
C
7850 |
NOT SCANNED
T
C
A
G
T
G
G
C
T
G
T
A
G
A
A
G
A
G
C
G
G
A
T
A
T
T
G
G
T
G
A
A
C
C
A
C
A
A
A
T
G
C
T
G
C
T
G
C
C
T
7900
G
A
T
C
G
T
T
C
C
T
C
T
G
G
A
A
G
T
T
T
T
G
T
C
T
C
A
G
A
G
G
A
G
T
A
C
C
C
G
A
C
C
G
T
G
T
G
A
G
G
7950
T
G
T
C
A
G
T
C
C
G
C
C
C
C
T
A
C
T
G
G
G
G
G
G
T
G
C
C
T
C
C
C
A
G
T
T
A
G
G
C
T
A
C
T
C
G
G
G
G
G
8000
T
C
A
G
G
G
A
C
C
C
A
C
T
T
G
A
G
G
A
G
G
C
A
G
T
C
T
G
C
C
T
G
T
T
C
T
C
A
G
A
T
C
T
C
A
A
G
C
T
G
8050
C
G
T
G
C
T
G
G
G
A
G
A
A
C
C
A
C
T
G
C
T
C
T
C
T
T
C
A
A
A
G
C
T
G
T
C
A
G
A
G
A
G
G
G
A
C
A
T
T
T
8100
A
A
G
T
C
T
G
C
A
G
A
G
G
T
T
A
C
T
G
C
T
G
T
C
T
T
T
T
T
G
T
T
T
G
T
C
T
G
T
G
C
C
C
T
G
C
C
C
C
C
8150
A
G
A
G
A
T
G
G
A
G
C
C
T
A
C
A
G
A
G
G
C
A
G
G
C
A
G
G
T
G
T
C
C
T
T
G
A
G
C
T
G
T
G
G
T
G
G
G
C
T
8200
C
C
A
C
C
C
A
G
T
T
C
G
A
G
C
T
T
C
C
C
A
G
C
C
G
C
T
T
T
G
T
T
T
A
C
C
T
A
A
T
C
A
A
A
C
A
A
C
T
A
8250
A
C
T
C
A
G
C
A
A
T
G
G
T
G
G
C
C
G
C
C
C
C
T
C
C
C
C
C
A
G
C
C
T
C
G
C
T
G
C
C
A
C
C
T
T
G
C
A
G
T
8300
T
T
G
A
T
C
T
T
G
G
A
T
G
G
C
T
G
T
G
C
T
T
G
C
A
A
T
G
A
G
C
G
A
G
A
C
T
C
T
G
T
G
G
G
C
A
T
A
G
G
8350
A
C
C
C
T
C
C
A
A
G
C
C
A
G
G
T
G
C
A
G
G
A
T
A
T
A
A
T
C
T
C
C
T
G
G
T
G
T
G
C
T
G
T
T
T
T
T
T
A
A
8400
G
C
C
G
G
T
T
G
G
A
A
A
A
G
C
A
C
A
G
T
A
T
T
A
G
G
G
T
G
G
G
A
G
T
G
A
C
C
C
A
A
T
T
T
T
C
C
A
G
G
8450
T
G
C
C
G
T
C
T
G
T
C
A
C
C
C
C
T
T
T
C
T
C
T
G
A
C
T
A
G
G
A
A
A
G
G
G
A
A
T
T
C
C
C
T
G
A
C
C
C
C
8500
T
T
G
T
G
C
T
T
C
C
C
G
G
G
T
G
A
G
G
C
A
A
T
G
C
C
T
C
G
C
C
C
T
G
C
T
T
T
G
G
C
T
T
G
C
G
C
A
C
G
8550
G
T
G
C
G
C
T
T
C
A
C
C
C
A
C
T
G
T
C
C
T
G
C
A
C
C
T
A
C
T
G
T
C
T
G
G
C
A
C
T
C
C
C
C
A
G
T
G
A
G
8600
A
T
G
A
A
C
C
C
G
G
T
A
C
C
T
C
A
G
T
T
G
G
A
A
A
T
G
C
A
G
A
A
A
T
C
A
C
C
A
G
T
C
T
T
C
T
G
T
G
T
8650
T
G
C
T
C
A
T
G
C
T
G
G
G
A
G
C
T
G
T
A
G
A
C
C
A
G
A
G
C
T
G
T
T
C
C
T
A
T
T
T
G
G
C
C
A
T
C
T
T
G
8700
G
C
T
C
C
T
C
C
C
C
TCAGCACAGT TTTTAGCATG AACTAAGGCC TCAATAAATA
8750
TTAGTTCCCT TCTCCAATTC AGAAAGTTGT CTGCCTTGAT AAGACAATTG
8800
TTTTTATTGT GAAAGTGAGG TGGAGATGGG GGATTGTCTC TCCTATAAAA
8850
GGTCTAAGAA GTTAGCAAAT GCTGTTTTTC CTTTTTGCTC CTCAGTTGCA
8900
TAAGTACATG GTAGAAATTG GGTCACTTTG CCTAAACCGG TTTTCTATAA
8950
CCTATTAAGT ATTAAAAGCT TGACACAGAT AAGTAGAGGC TGA
T
AAGATT
9000 |
var(8994):[A:0.07]
CTGTCCTGCA CCCCACTCCT ATCAAATTTG GAAGAACTGA CCTCTTCCGG
9050
GAAGAATTGC AATGCTAAAT CCAAATGCCT ATGGTTCT
A
T CTTATAAACA
9100 |
var(9089):[G:0.01]
AATGGTGTCC TCAAAATTCA TTTATGTAAA TCATTTGAAA TTTAAGAAAA
9150
AAATATGTTC AGAGAAAAAT ATGTTAAATG TCAAGGTGAA TTAGAAAGTG
9200
TGGCATTTAG TCAAGCATAA ATTAATATTC CAACTTTCTA GTTACTTTGT
9250
AGTAACTTAT TTAACATTTT GGTGAAATGA
G
GAACAAAGT G
T
CCACCTTT
9300 |
var(9281):[A:0.01]
|
var(9292):[C:0.34]
TTTTCCTGAA TATTTTATCT GAAGATCTAG GAGAGAGATG TGAAATAGTA
9350
T
T
TTTCTGGG GAAGTAGG
G
G AAATACAAAG AAAAGTAATG ACTTCAGGTA
9400 |
var(9352):[G:0.06]
|
var(9369):[A:0.10]
TAT
T
C
T
C
C
A
C
T
G
G
T
A
C
A
G
C
A
G
G
A
T
G
G
G
A
G
A
T
A
T
T
A
T
C
A
A
C
A
G
G
T
G
G
T
A
A
G
9450 |
NOT SCANNED
T
A
T
A
A
A
A
A
T
A
T
T
G
A
A
G
A
G
G
T
A
C
A
A
T
T
T
G
G
A
T
C
A
G
C
A
T
T
A
C
A
A
C
C
A
A
G
A
A
T
9500
G
G
A
G
A
A
T
G
A
C
A
T
T
C
A
G
G
A
T
T
G
A
A
A
G
A
A
A
C
A
T
A
C
A
A
G
A
G
G
G
C
A
G
A
A
A
G
C
T
T
9550
T
C
T
T
C
T
T
G
G
G
A
C
T
G
T
G
G
T
T
T
C
A
T
G
T
G
T
C
T
G
C
A
G
G
T
G
C
T
A
T
G
G
G
T
A
T
A
T
T
G
9600
A
G
A
A
T
G
G
T
T
C
T
A
A
A
A
A
C
A
G
G
G
G
C
T
T
G
G
T
T
T
A
G
G
T
T
G
T
G
A
A
G
A
C
C
A
T
C
A
A
A
9650
T
A
G
A
A
A
C
T
G
T
G
A
A
T
T
T
T
A
T
T
T
T
G
T
G
T
C
G
T
T
A
A
A
G
G
G
A
T
C
T
T
T
G
A
A
A
G
A
T
T
9700
C
T
T
A
G
G
A
T
A
A
A
T
A
T
G
A
T
A
T
G
C
A
T
A
G
G
A
T
A
G
A
A
A
G
A
A
A
G
G
T
G
G
G
A
G
A
C
A
G
G
9750
A
C
A
A
A
C
A
G
A
A
G
T
T
A
A
T
C
A
A
T
T
G
A
A
A
T
A
A
A
C
C
A
G
G
T
T
T
G
G
A
G
T
G
G
T
G
G
G
A
C
9800
A
A
T
A
G
C
C
T
T
C
A
A
G
A
C
A
T
C
A
A
G
A
A
T
A
T
T
T
G
T
T
A
G
T
A
G
A
A
A
G
A
A
A
A
T
C
G
A
A
G
9850
C
C
T
A
A
A
A
C
T
A
A
A
G
G
A
A
G
A
C
T
A
T
C
C
A
C
C
T
T
G
C
A
A
G
T
C
A
T
A
C
A
G
A
G
A
T
A
T
T
T
9900
G
C
T
A
T
T
A
T
A
T
A
A
T
T
T
T
T
T
T
A
A
A
A
A
A
A
G
A
T
T
T
C
C
T
A
A
T
A
T
T
T
A
A
A
T
T
A
T
G
A
9950
A
G
A
A
A
G
A
G
A
T
A
G
A
A
A
C
A
G
A
T
A
T
T
C
A
T
G
G
A
A
A
A
A
A
T
G
G
G
G
T
G
A
A
A
T
T
A
A
T
C
10000
A
A
A
G
G
G
C
A
G
C
T
T
A
T
T
A
C
C
T
T
G
A
G
A
C
T
A
A
A
C
A
G
C
C
A
T
T
G
A
C
T
T
T
T
T
T
C
T
T
A
10050
C
C
T
C
A
C
T
G
A
A
C
C
C
A
G
A
A
A
C
C
C
G
A
C
A
T
A
T
C
T
A
G
G
T
A
C
A
G
G
C
A
T
G
C
A
T
A
A
A
A
10100
C
A
T
G
T
A
C
A
C
A
C
A
C
A
A
A
A
T
G
T
A
A
T
A
A
T
T
G
G
A
G
T
T
C
A
C
T
T
A
G
A
G
G
T
A
C
A
C
A
T
10150
G
T
A
T
G
G
G
T
T
T
C
T
G
T
A
T
T
C
A
A
C
C
A
T
A
T
G
T
T
G
A
T
A
T
A
T
A
C
T
C
A
C
A
T
A
T
A
T
G
T
10200
A
A
G
T
G
A
T
A
A
T
A
T
C
C
T
G
T
T
T
G
T
T
A
C
T
T
C
C
A
C
A
T
T
T
A
T
G
C
A
C
T
A
T
C
C
C
T
T
A
A
10250
A
T
A
T
G
T
A
T
T
A
T
A
T
A
T
A
T
T
T
A
T
A
T
T
A
T
T
C
A
G
A
A
T
C
C
A
T
C
A
G
C
C
C
T
T
G
T
T
G
A
10300
A
T
A
A
A
T
T
A
G
T
G
A
A
T
A
A
A
A
T
A
T
A
G
A
G
T
C
G
A
G
T
C
T
C
A
T
T
A
T
T
C
A
C
A
G
A
T
T
C
T
10350 |
REPEAT
A
T
A
T
A
A
G
A
A
A
A
T
T
T
G
T
C
T
A
T
T
C
A
C
T
A
A
A
A
T
T
C
C
T
T
T
G
T
A
A
C
A
C
C
A
A
A
A
T
C
10400
A
A
T
A
C
T
G
C
T
G
G
A
C
T
T
T
C
A
T
G
G
G
C
A
T
T
C
A
C
A
T
G
C
A
T
G
T
G
C
A
A
A
G
T
G
G
T
G
A
A
10450
A
A
A
T
T
T
G
A
G
C
T
G
C
C
A
T
G
T
T
C
C
C
A
A
C
T
A
A
G
G
T
T
G
A
A
C
A
A
A
A
T
G
A
A
G
C
T
C
T
G
10500
T
C
T
T
C
T
T
G
T
T
T
C
T
G
C
T
C
A
C
A
T
A
T
G
A
T
A
A
A
G
A
A
A
T
A
T
C
C
T
T
T
T
C
A
C
A
C
T
G
T
10550
A
T
T
T
A
T
T
G
C
C
A
C
A
T
T
T
T
T
G
G
C
A
T
T
T
T
T
G
T
G
T
T
T
T
G
T
G
T
T
T
C
T
G
A
G
T
T
G
A
A
10600
T
G
T
T
T
C
G
A
A
T
G
G
G
C
C
C
C
A
A
A
G
A
T
A
G
T
G
C
T
G
A
A
G
T
G
C
T
C
T
C
C
G
G
T
G
C
A
C
A
A
10650
G
A
G
T
A
T
C
T
G
A
G
G
G
A
A
A
A
G
A
T
A
C
A
T
A
T
G
C
T
G
T
A
T
A
A
G
C
T
T
C
C
T
C
C
A
G
G
C
C
T
10700
G
A
A
C
T
A
C
A
G
T
G
T
T
G
T
T
G
A
C
A
A
C
T
A
A
T
T
C
A
A
T
G
T
T
A
A
T
G
A
A
T
C
A
A
T
A
G
T
A
T
10750
G
T
A
T
T
A
A
A
T
A
A
A
G
T
G
T
C
T
T
T
A
A
A
C
A
A
A
A
C
A
T
A
C
A
T
A
A
A
A
C
A
C
A
G
T
T
C
T
A
T
10800
A
T
T
G
A
A
C
A
A
T
T
T
A
C
C
A
A
A
A
T
A
T
T
G
T
G
A
C
C
A
G
A
G
G
C
A
G
A
C
A
G
G
C
A
T
A
T
A
A
C
10850
T
A
A
C
C
C
C
A
C
A
T
C
T
C
T
C
C
A
A
G
G
A
A
C
A
A
T
G
G
T
T
C
A
A
T
A
T
T
T
G
C
T
A
A
T
T
C
A
G
T
10900
G
T
T
C
C
C
A
G
C
A
A
C
T
T
T
A
T
A
A
A
A
C
A
T
A
A
C
T
A
C
T
G
C
A
A
C
A
A
G
T
A
T
C
A
A
C
T
G
T
A
10950
C
A
T
A
T
A
A
T
A
T
A
T
A
T
T
A
G
A
C
A
T
A
T
T
G
T
A
T
A
A
T
T
A
C
T
G
C
C
C
T
A
T
T
A
A
A
A
A
T
C
11000
A
T
G
T
A
T
C
T
A
T
G
C
T
G
T
G
T
C
T
G
C
T
T
A
T
A
T
A
G
A
T
A
T
C
T
T
A
G
A
T
A
C
A
T
A
A
A
T
A
T
11050
G
T
A
T
T
G
T
T
T
A
C
A
T
A
C
A
T
A
G
G
A
G
C
A
A
G
A
A
T
G
T
A
T
T
T
C
T
A
A
A
A
C
T
C
C
A
T
G
A
A
11100
G
A
A
C
A
C
A
T
T
A
T
A
T
T
C
T
A
T
A
T
A
A
A
A
G
A
G
T
C
A
G
T
T
G
A
A
G
T
A
A
A
A
A
G
T
T
A
A
C
T
11150
C
A
T
T
T
T
A
C
T
A
G
T
C
T
T
T
A
A
A
G
T
A
G
G
A
C
T
T
T
A
A
T
G
A
C
T
C
T
C
A
A
A
A
T
A
A
C
A
A
T
11200
T
T
C
T
C
T
C
A
T
A
C
A
T
T
G
A
C
T
C
C
A
A
A
A
C
T
T
T
A
G
T
T
G
T
T
G
A
A
T
T
T
A
T
T
C
T
G
C
A
G
11250
A
T
A
T
G
G
C
C
A
C
A
T
A
A
A
A
C
C
A
A
A
A
T
G
G
C
A
T
A
T
G
A
T
A
T
A
T
T
A
A
G
A
A
C
A
T
C
T
T
T
11300
A
A
T
A
T
G
A
A
A
T
G
A
T
T
A
G
A
T
A
C
A
A
C
C
T
A
A
A
A
G
C
T
G
A
T
G
A
A
T
A
T
A
G
A
A
C
C
A
G
T
11350
T
G
C
A
T
A
T
A
T
T
A
T
G
G
A
C
A
A
C
T
T
A
A
T
A
C
C
C
T
G
C
T
A
C
C
A
T
A
A
G
A
A
A
A
A
T
G
A
G
A
11400
A
A
G
A
C
T
T
A
T
T
A
A
G
A
T
T
A
A
G
T
A
T
A
T
A
G
A
G
A
A
G
A
T
A
A
A
A
A
G
G
T
A
G
A
G
A
A
T
G
A
11450
T
G
T
T
T
A
A
G
G
T
A
T
G
C
T
A
C
C
A
T
T
T
G
C
A
T
T
G
A
A
A
A
G
G
A
A
A
A
T
A
T
T
A
T
G
T
A
C
T
T
11500
A
A
T
G
A
A
A
A
A
T
C
C
A
T
A
T
T
A
T
A
T
T
T
C
T
G
G
A
T
A
A
T
G
G
G
A
C
A
A
G
A
G
T
T
A
G
A
G
G
A
11550
A
G
A
A
T
C
T
T
T
G
T
T
T
T
A
T
T
T
T
T
T
T
A
A
T
T
T
G
C
A
T
T
T
T
C
A
A
C
T
A
T
A
T
G
C
A
T
T
T
T
11600
C
T
C
T
T
G
G
A
A
A
A
G
A
A
A
T
G
A
A
C
A
A
A
A
T
C
A
A
A
A
T
A
A
A
G
T
A
A
C
A
T
C
A
T
G
A
T
G
G
T
11650
G
G
T
A
A
G
G
T
C
A
A
G
C
A
A
T
A
C
C
A
G
A
G
T
T
G
C
T
C
T
G
AGAAGTACT TGGAGTACAC
11700
TTTGCTCTTT TTAACAAATC CAAATTCTGT TTGCTTTTTG AGCCTGATTC
11750
CAGTGGTGT
C
TCCTTTATAA AACTGAGGCC ATTCTAATTT AATTCTTTAT
11800 |
var(11760):[T:0.08]
ATTATTTTTG TATCTGTTTT GAATATCTAC TCTGTGCAAG GGGCTAATAG
11850
GCACATTTTA AAACTAGAAG GATAAAGAAA ACATATATTT GCTTTTATAA
11900
ATTTTACAAT ATAGGTGTGT AGAAAAGATA ATAATTTAAA TTTCTATAAT
11950
TTAAAATGTT CATGTAATCT GG
T
GTGTGAT TCTATATTAC TT
A
C
T
T
GTTT
12000 |
var(11973):[C:0.01]
|
var(11993):[:0.20]
CAAATT
T
C
T
C
T
C
C
A
C
A
A
A
T
T
T
A
T
T
T
T
T
C
T
A
T
T
A
A
A
T
T
G
T
A
A
T
C
T
C
C
T
T
A
G
12050 |
REPEAT
G
C
T
A
G
A
A
T
T
T
G
T
G
T
C
T
G
T
C
T
T
T
C
C
T
A
C
T
T
T
T
G
T
G
T
C
C
A
G
C
A
T
T
G
A
C
C
T
A
G
12100 |
var(12084):[T:0.11]
C
A
G
A
G
T
G
G
T
A
A
C
G
A
C
A
T
A
G
T
A
G
A
C
C
C
T
G
A
G
T
G
A
A
T
G
T
T
A
G
T
G
A
A
T
G
G
T
T
G
12150 |
var(12120):[C:0.02]
A
TTGATTGAT GATGATCTTG TGGCTTTTCT TATTTCTAAA TTATATATTG
12200
TAAAAATAAA ATAAACTATA CTTTTTCTTC CTTAATAG
G
T
G
A
T
T
G
T
T
T
C
A
12250 | Exon 2 |
UTR
A
A
C
T
G
A
G
C
A
T
C
A
A
C
A
A
C
A
A
A
A
A
C
A
T
T
T
G
T
A
T
G
A
T
A
T
C
T
A
T
A
T
T
T
C
A
A
T
C
A
12300
T
G
G
A
C
C
A
A
A
A
T
C
A
A
C
A
T
T
T
G
A
A
T
A
A
A
A
C
A
G
C
A
G
A
G
G
C
A
C
A
A
C
C
T
T
C
A
G
A
G
12350 |
var(12329):[G:0.01]
M D Q N Q H L N K T A E A Q P S E 17
A
A
T
A
A
G
A
A
A
A
C
A
A
G
A
T
A
C
T
G
C
A
A
T
G
G
A
T
T
G
A
A
G
GTAGAAT AAGTTTTATG
12400
N K K T R Y C N G L K 28
TTTTTGAGCT AAAATAAGTA AATAGGGAAC TTTAATGTAT AGAAAAGCAA
12450
GTTGTTAAAA AGAACATTAT GTTTCAAATT ATAATTTTCA ATTGAAGCAT
12500
A
TATTGAAAT ATTAACATAA TGATTCATAC CTTGATTTAA ACCAGTCTTT
12550 |
var(12501):[G:0.01]
TAATCTGATT AAGTATTTCT TTGGC
G
AAAT TTTTG
A
TGC
T
T
AATAGTTTA
12600 |
var(12576):[A:0.01]
|
var(12586):[T:0.09]
|
var(12590):[C:0.01]
|
var(12591):[A:0.01]
TCAATGTAGA AAATTTAGAA ATATTTTGAT
A
GCTTCTCTT TGGTTTTGGA
12650 |
var(12631):[G:0.13]
TTGATCACGA CATATTTAGG AATGTGATTA AAATAAAAAA TGCATAATGA
12700
ATAATATTTT AAAATTCTTA GAATTGACTT ATAAACTTAG AATATTAATG
12750
TCTTGAGACT CACTTTGTGA TACTGACTTA TTTAAAAATT
C
TTTTAAAAA
12800 |
var(12791):[A:0.07]
AAAAAACAAA AAACAGGATT TAAAAAAGTT CTGATAAGTA ATTTAGGCTC
12850
ATGGAACGGA GGTCTATGAT AGTCAAAAAC TTGGCCAAAA GACCTGTTTG
12900
ACGATTTAGA AAAGCCATTT AATGTTTTCA TTTGCCAGCT GGTA
A
AAGTA
12950 |
var(12945):[C:0.01]
ATAATTCTGC TTTTTGCTTT TGGCACAAAC TGTATTAAAT GATACAGTTG
13000
AGGTATTAAG TGATGCTGGC ATTTTTATAA ACAGGAATGA GTACTCCTAA
13050
GCACAATGCT
A
A
A
T
G
A
G
A
A
G
C
C
A
A
G
A
C
T
C
A
G
A
A
A
A
G
T
T
A
A
G
A
A
A
T
T
T
T
C
C
13100 |
REPEAT
T
G
A
A
G
T
C
A
T
C
T
A
C
A
T
T
G
T
G
A
A
T
T
G
A
A
A
A
C
C
C
T
G
G
A
A
C
C
C
A
A
G
ACAAAGCC
13150
TTTAAATCCC CATATGGAAG TCTTGAGGAA ATCAAGAAAT AAGGGTCACC
13200
TTTTATCAAT GTTTTAACTT TTTTATTTAG TCAAATTTGT AGTCTTATAC
13250
AGCTGAATAA AGGCCACCAA GATTGGAGTC AATTACAATA ATGTTATAAA
13300
AGGTTCCTTT TAGCTCCTTC CAGGGAACAT AAAATTTGTT TGTTTTCTGA
13350
GATTACTGAT AAAGCCTTCT CTGATGAAAT ATTTGAGTAA CATTTAGGCC
13400
AA
G
TGGCAGT CATAAGGAAA AAGTATTGGT TAATGCAAGT GAATTATGTT
13450 |
var(13403):[A:0.25]
CTATATTCTA AGGATAATAT AATGTACTGA ATTGTTTTTA TTTTTAAATA
13500
CTGAGTGTTA CAGTAATTTC ACTGACATGT GCATAGCAAA ATGGCAGCAA
13550
ACTGCCTGAA GCAATAAAAT TTCCAGAGTG ATCCCTTATA GCATATCTGG
13600
AGAAGCTGGG AGTTAGGGAA TTAGCAGTGT GTGGAAAGGA CATTAACTGC
13650
AGCCCAATAA AGAAGACTAG AGCTAGAGGA AGATACTGGG ATAAGACTGG
13700
CATCCCTAAT GCTGGTATTT CAGAAACATC GCTAAATTGG TTAATCATGT
13750
CTACAAGTGA TATTTAAAAT AATATTTTCA CTCACTTAAA TTGTTAACAT
13800
TGATATGTTG TTGATAAAGA ATATTAAACT CAACAATCAT TTTACAATAA
13850
TTCTGTAAAG ACTTGCGTGC CTGTAGTTGA GGTTTGTTGC ATTTCTGAGC
13900
TTACTTTTTA TTCATGAGAA ATGAAAACAT AATGGGAGAA AATTTTTTAA
13950
ATAAAGGGTA TTTTAATTTT TTATGAAGTT TGGGACTTCA AAGTATTAAC
14000
AAAAGTTGCT GAAAATA
T
AT TGACTTTTAC TTTCATTAAA TTACATTTTA
14050 |
var(14018):[A:0.14]
TCATCTAATT T
C
TTAATTTT CTGTATTTGA AATATTATGA TTTAGAGATA
14100 |
var(14062):[T:0.14]
TCTCTGTAGA TAGAAAGATA ATG
A
A
A
A
C
A
A
T
A
G
T
A
A
A
A
C
A
A
A
T
G
T
A
A
T
T
C
14150 |
NOT SCANNED
A
G
G
A
G
C
A
T
A
A
A
A
A
A
A
G
A
T
G
A
G
A
G
A
A
A
C
C
T
T
A
A
T
A
A
T
A
G
T
A
G
C
T
A
A
C
A
T
T
T
14200 |
REPEAT
A
T
C
A
A
G
C
A
T
T
T
A
C
T
A
T
A
T
G
C
C
A
G
A
C
A
T
T
G
A
T
T
T
A
G
T
G
T
T
T
T
A
C
T
T
T
T
G
C
T
14250
A
A
C
A
G
A
T
T
T
T
T
T
C
C
T
T
A
C
C
A
T
A
A
T
T
C
T
A
T
C
A
A
C
T
G
G
A
T
G
G
T
A
T
T
A
T
C
T
C
C
14300
C
C
T
T
T
T
C
A
G
A
T
G
A
A
A
A
A
A
C
C
T
A
G
A
T
A
T
A
G
A
C
A
G
G
G
C
A
A
A
T
G
T
C
T
T
C
T
C
C
T
14350
A
G
G
T
C
T
C
A
A
A
G
T
T
G
G
T
A
A
T
T
G
G
T
A
C
A
C
T
G
A
A
G
G
T
C
T
G
A
A
C
T
C
A
G
G
C
A
A
T
C
14400
T
G
A
T
T
C
C
A
A
A
T
C
C
T
A
T
G
C
T
C
T
C
A
A
C
T
G
T
A
T
T
C
C
A
T
A
T
T
G
C
T
A
A
A
A
T
A
A
A
T
14450
G
T
G
G
A
T
T
T
T
T
G
T
A
A
T
A
T
T
A
G
T
A
C
C
C
T
C
A
A
G
A
T
G
T
T
A
T
G
G
C
A
A
G
C
A
G
G
C
T
T
14500
T
T
A
T
A
A
G
T
G
G
T
G
T
C
T
T
T
A
A
T
A
A
C
T
T
T
C
C
T
C
A
T
T
C
C
A
T
A
C
T
T
C
T
A
A
A
A
A
A
T
14550
T
A
T
C
T
T
A
A
G
G
T
T
A
A
A
T
T
A
T
T
G
A
G
T
G
T
C
A
A
G
C
A
A
C
T
G
T
G
G
A
T
T
C
T
A
A
C
A
C
T
14600
T
G
C
T
A
A
C
A
T
G
C
A
T
G
C
A
C
A
C
A
C
C
C
A
A
A
T
A
T
A
C
A
T
G
T
T
G
T
T
A
C
T
G
A
C
T
T
A
C
A
14650
T
A
T
A
C
A
G
A
C
A
C
A
G
C
A
G
G
T
G
G
C
A
A
T
A
T
A
T
A
A
G
T
G
C
A
A
A
T
T
G
A
T
A
A
T
A
T
A
T
C
14700
C
G
T
G
G
A
A
A
T
A
C
A
A
A
C
A
A
A
A
C
T
T
T
G
A
G
A
A
A
T
C
A
A
A
T
A
C
T
T
G
A
A
T
T
C
T
T
T
T
C
14750
T
A
C
C
C
C
T
T
C
T
C
C
T
C
A
A
T
T
T
T
T
G
T
A
C
T
G
A
A
C
T
A
A
C
T
A
C
A
T
T
A
C
A
T
A
G
A
A
C
C
14800
T
G
C
T
A
G
T
A
T
A
T
G
T
T
T
C
A
T
C
A
T
T
A
C
A
C
T
T
G
T
C
A
T
T
T
C
T
T
C
T
C
T
T
C
A
A
A
T
T
T
14850
A
A
A
C
C
C
A
A
C
A
A
G
A
T
A
C
A
G
G
G
G
A
A
G
A
T
T
T
A
A
A
T
G
C
A
A
T
C
C
A
A
A
G
A
A
A
A
C
A
G
14900 |
REPEAT
G
A
A
A
A
C
A
A
T
T
C
A
A
G
A
G
T
T
T
A
A
A
G
A
T
G
A
C
A
T
A
G
T
C
A
T
T
T
T
A
A
G
A
A
A
G
A
A
C
C
14950 |
var(14947):[T:0.01]
A
A
A
A
T
T
A
A
C
T
T
C
T
G
A
A
A
T
T
A
A
A
T
A
T
T
T
T
A
C
T
A
C
A
G
G
A
A
T
T
T
C
A
T
A
A
T
A
C
A
15000
A
T
T
A
T
A
G
T
A
A
T
T
A
A
C
A
A
C
A
A
A
A
T
A
G
A
C
C
A
A
G
C
T
T
A
A
G
A
A
A
G
A
A
T
C
T
C
A
G
A
15050
G
T
T
T
G
A
A
G
A
T
T
A
C
C
C
C
T
T
T
G
A
A
T
C
A
A
C
A
C
A
A
G
C
A
G
A
C
A
A
A
A
T
T
A
A
A
G
G
A
A
15100
A
A
A
T
A
T
T
A
A
T
G
A
A
A
A
A
A
A
C
C
T
C
T
G
A
G
A
A
A
T
A
T
G
G
G
A
T
T
A
T
G
T
A
A
A
G
A
G
A
C
15150
C
A
A
G
C
C
T
G
T
G
A
C
T
C
A
T
T
G
G
C
A
T
T
C
C
T
G
A
A
A
G
A
G
G
A
G
A
A
A
G
A
G
T
A
A
G
C
A
A
C
15200
T
T
G
G
A
A
A
A
T
G
T
C
T
T
T
G
A
G
G
A
T
A
A
A
G
T
C
C
A
T
G
A
A
A
A
A
T
T
T
C
C
C
A
G
T
C
T
T
G
C
15250
T
A
G
A
G
A
G
G
T
G
G
A
T
A
T
G
C
A
A
G
T
T
C
A
A
A
A
A
A
T
T
C
A
A
A
G
A
A
T
C
C
C
T
T
C
A
A
G
A
T
15300
A
C
T
A
T
A
C
A
A
G
A
T
G
G
T
C
A
T
C
C
A
C
A
A
G
A
C
A
C
A
T
A
A
T
C
A
T
C
A
G
A
T
T
C
T
C
C
A
A
G
15350 |
var(15341):[G:0.47]
G
T
A
A
A
C
A
A
G
A
A
A
G
A
A
A
A
A
A
A
C
C
T
T
A
A
A
G
G
C
A
G
C
T
A
G
A
G
A
G
A
A
G
G
G
G
C
A
G
G
15400
T
C
A
C
T
T
A
C
A
A
A
A
G
G
A
G
C
C
C
C
A
T
C
A
G
T
C
T
A
A
C
A
A
T
A
G
A
T
C
T
T
T
C
A
G
C
A
G
A
A
15450
A
G
C
T
T
A
C
A
A
G
C
T
A
G
A
A
G
A
G
A
T
T
G
G
G
G
A
C
C
T
A
T
T
T
T
C
A
C
C
A
T
C
C
T
T
A
A
A
G
A
15500
A
A
A
G
A
A
A
T
T
G
C
A
A
C
T
A
A
G
A
A
T
T
T
T
A
T
A
T
T
C
T
G
C
C
A
A
A
C
T
A
A
G
C
T
T
C
A
T
A
A
15550
G
T
A
A
A
G
A
A
A
A
A
A
T
A
T
T
A
T
T
T
T
C
G
G
T
C
A
A
G
C
A
A
A
T
G
C
T
A
A
C
A
G
A
A
T
T
T
G
T
T
15600 |
var(15589):[G:0.10]
A
C
C
A
T
T
A
G
A
C
C
T
G
C
C
T
T
A
C
C
A
G
A
G
A
T
G
C
T
T
A
A
G
G
G
A
G
T
C
C
T
A
A
A
C
A
T
G
G
A
15650
A
A
T
G
A
A
A
G
A
A
T
G
A
T
A
C
C
T
G
T
C
A
C
C
A
C
A
A
A
A
A
T
A
G
A
C
T
T
A
A
C
T
A
C
A
G
A
G
C
C
15700 |
var(15665):[G:0.06]
C
A
C
A
G
A
C
A
T
T
A
T
A
A
A
G
C
A
A
T
T
A
T
G
C
A
A
T
C
A
A
G
C
C
A
A
C
A
T
A
A
T
A
A
C
C
A
G
C
T
15750
A
A
C
A
A
C
A
C
T
A
T
G
A
C
A
G
A
A
T
C
A
A
A
T
C
C
T
C
A
C
A
T
A
T
C
A
G
T
A
T
T
A
A
T
C
T
T
G
A
A
15800
T
G
T
A
A
A
T
G
G
G
T
T
A
A
A
T
G
C
C
T
A
C
A
C
T
T
A
A
A
A
G
G
C
A
T
A
G
A
A
T
A
G
C
A
A
G
T
T
G
G
15850
A
T
A
A
A
G
A
A
G
C
A
A
G
A
C
C
C
A
A
C
C
G
T
T
T
T
G
T
T
G
T
C
T
T
C
A
T
G
A
C
T
C
A
T
G
T
A
T
C
A
15900
T
G
A
C
A
T
C
C
A
T
A
A
G
A
T
A
G
A
A
A
A
T
G
A
A
T
A
A
A
T
T
G
A
A
A
T
A
A
T
A
T
T
TATCTCAG
15950
AGTTGTCAGG
A
T
A
T
T
T
A
T
A
A
G
G
T
G
C
T
T
A
G
C
A
C
A
G
T
G
T
T
A
C
A
T
A
G
A
A
A
C
T
C
16000 |
REPEAT
A
A
T
A
A
A
T
TGG AAAGTTCCAA CATAGTAGCA TTATAGTTGC TGCAC
T
T
T
T
T
16050 |
REPEAT
T
T
G
A
G
A
C
A
G
G
G
C
C
T
C
T
G
T
C
A
C
C
C
A
G
G
C
T
G
G
A
G
T
G
C
A
G
T
G
G
C
A
T
A
A
T
C
T
T
G
16100
G
C
T
C
A
C
T
G
C
A
A
A
C
T
C
C
A
C
C
T
C
C
C
A
G
G
C
T
C
A
A
G
T
G
A
T
T
C
T
C
C
C
A
C
C
T
C
C
T
G
16150
A
G
T
A
G
C
T
G
G
A
A
C
T
A
C
A
G
G
C
A
C
A
T
G
C
C
A
C
T
T
C
A
C
C
C
A
G
C
A
T
T
T
T
T
T
T
C
A
T
T
16200
T
T
T
T
T
T
T
T
T
T
T
T
T
T
T
T
T
T
T
T
T
T
T
T
A
G
T
A
G
A
G
A
T
G
A
G
G
T
C
T
T
A
C
C
T
T
G
T
T
G
16250
C
C
A
G
G
C
T
G
G
T
C
T
T
A
A
A
T
T
C
C
T
A
G
G
C
T
C
A
A
G
C
A
A
T
C
A
G
C
C
C
G
C
C
T
T
G
G
C
C
T
16300 |
var(16291):[A:0.02]
C
C
T
A
A
A
G
T
G
C
T
G
G
A
A
T
T
A
C
A
G
G
T
A
T
G
A
G
C
C
A
T
C
A
C
A
T
C
T
G
G
A
A
G
C
T
G
T
T
T
16350 |
REPEAT
C
T
T
T
T
T
A
A
A
G
T
G
A
C
T
A
C
A
T
T
A
A
T
T
T
A
C
T
T
G
A
T
C
A
C
G
A
G
T
A
A
T
A
C
A
T
A
A
A
T
16400
G
A
A
A
A
T
T
T
G
A
G
A
A
T
A
C
A
T
T
C
A
C
T
C
C
A
A
T
A
T
T
T
G
G
A
A
T
T
A
T
G
T
G
A
C
T
T
C
T
A
16450
G
A
T
T
T
T
T
G
C
A
A
T
T
T
A
A
G
T
A
G
G
C
A
T
A
A
A
A
T
G
G
T
A
C
T
T
T
G
T
T
T
T
G
G
T
ATTTG
16500 |
var(16493):[A:0.12]
TCTGTGCTCC TTGATTCTTA TAAATATTAT ATTTTGTGAA ATCC
A
TTGCT
16550 |
var(16545):[G:0.10]
GAAT
G
CAAGT GGTGCTGGTT ACATTTGCCT ATTTCCAAGT TTTAGTACAT
16600 |
var(16555):[A:0.01]
TTATTTTTGA AATATATTTT ATCAGTTTAA GGACTTA
C
T
T
G
T
A
A
T
A
T
C
T
T
16650 |
REPEAT
T
G
T
G
T
G
G
T
C
T
T
G
G
T
A
T
T
A
G
G
T
T
A
A
T
G
T
T
G
G
C
C
T
C
A
A
T
A
A
A
T
G
A
G
A
T
A
G
G
A
16700
A
G
T
A
T
T
T
T
T
T
T
C
T
G
C
T
T
C
T
A
A
C
C
T
C
T
G
A
A
A
A
A
A
A
C
T
G
T
A
G
A
G
A
A
T
T
G
A
T
A
16750
T
A
A
A
T
T
A
A
T
T
C
T
T
A
G
G
T
A
T
T
T
G
G
T
A
G
A
A
T
T
C
A
A
C
A
G
T
G
A
A
A
C
C
A
T
G
T
A
G
G
16800
C
C
T
G
T
T
T
C
T
T
T
C
T
G
T
T
T
T
G
G
A
A
A
G
T
T
A
T
T
A
A
A
A
T
C
A
G
T
T
C
A
A
T
T
T
C
T
T
A
A
16850
A
C
A
G
A
A
A
T
A
G
T
C
C
T
T
T
T
A
A
T
A
T
T
G
T
C
T
A
T
T
T
A
T
T
C
T
T
G
T
A
C
A
A
A
A
T
T
G
G
G
16900
T
A
G
A
T
C
G
T
G
T
C
T
T
T
C
A
A
T
A
T
A
T
T
G
G
T
C
T
A
T
T
T
T
A
T
A
T
A
G
G
T
T
A
T
C
A
T
A
G
T
16950
T
G
T
A
G
G
C
A
G
A
G
T
G
T
T
G
C
T
T
A
T
A
G
T
A
T
T
T
C
T
T
T
A
T
T
A
T
C
C
T
T
T
T
C
A
T
G
T
A
T
17000
A
T
T
G
G
A
T
C
T
G
T
A
G
T
T
A
T
G
T
C
C
C
C
G
C
C
T
T
T
A
T
T
T
C
T
G
T
T
A
T
T
A
G
T
A
A
T
T
T
G
17050
T
G
C
C
T
T
C
C
C
T
C
A
T
C
T
T
C
T
T
A
G
G
T
A
A
C
C
T
G
G
C
T
G
G
G
T
C
A
A
T
T
T
T
A
T
T
A
A
T
C
17100
T
T
T
C
T
A
A
A
G
A
A
T
T
A
A
C
T
T
G
T
G
G
T
T
T
T
G
T
C
A
A
T
T
T
C
C
T
C
T
A
T
T
G
A
T
T
T
C
C
T
17150
G
T
T
T
A
T
G
A
T
T
T
A
A
T
T
G
A
T
T
T
C
A
G
G
T
C
C
A
A
T
T
T
T
T
A
T
T
C
T
A
T
T
T
T
T
T
C
T
T
G
17200 |
var(17189):[C:0.02]
T
G
C
T
T
A
C
T
T
A
A
A
A
T
T
T
A
A
T
T
T
G
C
T
T
T
T
C
T
T
T
T
T
G
A
T
T
T
T
C
C
C
A
A
G
G
T
G
G
A
17250
A
A
C
T
T
A
G
A
T
A
T
T
G
A
T
T
T
T
A
G
C
A
T
T
T
T
C
T
T
G
T
T
T
T
C
T
A
A
C
A
T
A
T
G
C
A
T
T
C
A
17300 |
var(17264):[G:0.01]
G
T
G
C
A
A
T
A
A
A
T
C
T
C
T
A
A
G
T
C
T
T
G
A
T
T
T
T
G
C
T
A
C
C
T
T
T
C
A
C
A
A
A
T
T
T
T
G
A
T
17350
C
A
C
T
T
G
T
A
T
G
T
T
T
A
A
T
T
T
T
A
T
T
T
T
T
T
T
C
A
A
G
A
T
G
T
T
T
T
A
A
A
A
T
T
T
T
T
C
T
T
17400 |
var(17379):[C:0.17]
C
A
G
A
T
T
T
C
T
T
T
T
G
A
C
T
C
A
T
A
A
G
T
T
A
C
T
T
A
A
A
A
G
T
G
T
G
G
T
A
G
T
T
A
A
T
C
T
C
C
17450
A
C
A
T
A
T
T
T
T
G
G
T
A
T
T
T
T
T
C
C
A
G
T
T
A
T
C
T
T
T
C
T
G
T
T
A
T
A
T
T
C
T
A
G
C
T
T
A
A
T
17500 |
NOT SCANNED
T
T
C
A
T
T
G
T
C
A
T
C
T
A
A
G
A
G
A
A
G
A
C
A
T
T
A
T
T
A
G
T
T
T
A
A
A
T
G
T
G
T
T
A
A
G
G
T
G
T
17550
G
T
T
T
T
A
T
G
G
C
T
T
A
G
G
C
T
G
T
G
G
T
A
T
A
T
A
T
T
G
G
T
G
A
A
T
A
T
T
C
C
A
T
G
T
A
A
G
C
T
17600
T
A
A
G
A
A
G
A
A
T
G
T
G
T
A
T
T
C
T
G
T
T
G
T
T
G
T
T
G
G
A
T
G
A
A
A
T
A
A
C
A
T
A
T
A
G
A
T
G
T
17650
T
T
A
T
T
A
T
A
T
C
C
A
G
T
T
A
A
T
T
G
A
T
G
A
T
G
T
T
G
T
T
A
A
G
G
T
C
A
A
T
C
A
T
G
T
T
C
T
T
C
17700
C
T
G
T
T
T
T
T
A
C
C
T
G
C
T
G
G
A
T
C
T
T
T
C
C
A
T
T
T
C
T
A
G
A
G
A
G
A
T
G
T
A
G
A
G
T
C
T
C
C
17750
A
A
A
T
A
C
C
A
T
A
G
T
G
T
A
T
T
C
A
T
T
T
A
T
T
T
C
T
C
C
T
T
G
T
A
T
T
T
C
T
A
C
T
G
G
C
T
T
T
T
17800
A
C
T
T
C
A
G
A
T
A
G
T
T
T
G
C
A
G
C
T
C
T
G
T
T
G
T
T
T
G
G
T
G
C
C
T
C
T
A
T
G
T
T
A
A
G
A
A
G
T
17850
G
T
T
A
T
G
T
T
T
T
C
T
T
A
A
G
A
A
T
T
G
A
C
C
C
C
T
T
T
A
A
C
A
T
T
T
T
G
T
A
A
T
G
C
C
C
C
G
T
T
17900
T
T
T
A
C
C
T
C
T
G
T
T
A
A
T
T
T
C
C
T
T
G
C
T
T
T
A
G
A
G
T
C
T
G
C
T
G
T
G
T
C
C
A
A
A
A
T
T
A
A
17950
T
T
T
A
G
A
T
T
G
T
C
T
T
G
C
T
T
T
G
T
T
T
T
G
G
T
T
A
T
T
G
T
T
A
C
C
A
T
G
G
A
A
T
G
T
T
T
T
T
C
18000
T
C
C
A
C
T
T
C
T
T
T
A
C
T
T
T
T
T
T
A
A
A
A
A
A
T
T
A
C
A
C
T
T
T
A
A
G
T
T
C
T
G
G
G
A
T
A
C
A
T
18050 |
REPEAT
G
T
G
C
A
G
A
A
T
G
T
G
C
A
C
A
T
T
T
G
T
T
A
C
A
T
A
G
G
T
A
A
A
C
A
C
A
T
G
C
C
A
T
G
G
T
G
G
T
T
18100
T
G
C
T
G
C
A
C
C
C
A
T
C
A
A
C
C
C
G
T
C
A
T
C
T
A
C
A
T
T
A
G
G
A
A
T
T
T
C
T
C
C
T
A
A
T
G
C
T
A
18150
C
T
C
C
C
T
A
G
C
C
C
C
C
C
A
A
C
C
C
C
C
A
A
C
A
G
G
T
G
C
T
G
G
T
G
T
G
T
A
A
T
G
T
T
C
C
C
C
T
C
18200
C
C
T
G
T
G
T
C
C
A
T
G
T
G
T
T
C
T
C
A
T
T
G
T
T
C
A
A
C
T
C
C
C
A
C
T
T
A
T
G
A
G
T
G
G
G
A
A
C
A
18250
T
G
C
A
G
T
G
T
T
T
G
G
A
T
T
T
C
T
G
C
T
C
C
T
A
T
G
T
T
A
G
T
T
T
A
C
T
G
A
G
A
A
T
G
A
T
G
G
T
T
18300
T
C
C
A
G
C
T
T
C
A
T
C
C
A
T
G
T
C
C
C
T
G
C
A
A
A
G
G
A
C
A
T
A
A
A
C
T
C
A
T
T
C
T
T
T
C
T
T
T
T
18350
G
G
C
T
G
C
A
T
A
G
T
A
T
T
C
C
A
T
G
G
T
G
T
A
T
A
T
G
T
G
C
C
A
C
A
T
T
T
T
A
T
T
T
A
T
C
C
A
T
T
18400
C
A
A
T
T
A
T
T
G
A
T
G
G
G
C
A
T
T
T
G
G
G
T
T
G
G
T
T
C
C
A
A
G
T
C
T
T
T
G
C
T
A
T
T
G
T
G
A
A
T
18450
A
G
T
G
C
T
G
C
A
A
T
A
A
A
C
A
T
A
C
A
T
G
T
G
C
A
T
G
T
G
T
C
T
T
T
A
T
A
G
T
A
G
A
A
T
G
A
T
T
T
18500
A
T
A
A
T
C
C
T
A
T
G
G
A
T
A
C
A
T
T
C
A
A
C
A
A
T
G
G
T
T
G
A
A
T
T
A
A
T
T
T
A
C
A
C
T
C
C
C
A
C
18550
C
A
A
C
A
G
G
G
T
A
A
A
A
G
C
A
T
T
C
C
T
A
T
T
T
C
T
C
C
A
C
A
T
C
C
T
C
T
C
C
A
G
C
A
T
C
T
G
T
T
18600
G
T
T
T
C
C
T
G
A
C
T
T
T
T
T
A
A
T
G
A
T
C
G
C
T
T
C
C
A
A
C
T
G
G
C
G
T
G
A
G
A
T
A
G
T
A
T
C
T
C
18650
A
T
T
G
C
A
G
T
T
T
T
G
A
T
T
T
G
C
A
T
T
C
T
C
T
A
A
T
G
A
C
C
A
G
T
G
A
T
G
A
T
G
A
G
C
T
T
T
T
T
18700
T
A
A
T
A
T
G
T
T
T
G
T
T
G
G
C
C
A
C
A
T
A
A
A
T
G
T
C
T
T
A
T
T
T
T
G
A
G
A
A
G
T
G
T
C
T
G
T
T
C
18750
A
T
A
T
C
C
T
T
G
G
C
C
C
A
C
T
T
T
T
T
G
A
T
G
G
C
A
T
T
G
T
T
T
G
T
T
T
C
T
T
T
C
T
T
G
T
A
A
A
T
18800
T
T
G
T
T
T
A
A
G
T
T
C
C
T
T
G
T
A
G
A
T
T
C
T
G
G
A
T
A
T
T
A
G
C
T
C
T
T
T
G
T
C
A
G
A
T
G
G
A
T
18850
A
G
A
T
T
G
T
A
A
A
A
A
T
T
T
T
C
T
C
C
C
A
T
T
C
T
G
T
A
G
G
T
T
G
C
C
T
G
T
T
C
A
C
T
C
T
G
A
T
G
18900
A
T
A
G
T
T
T
C
T
T
T
T
G
C
T
A
T
G
C
A
G
G
A
G
C
T
T
T
T
T
A
G
T
T
T
A
A
T
T
A
G
A
T
C
C
C
A
T
T
T
18950
G
T
C
A
A
T
C
T
G
G
G
T
T
T
T
T
G
T
T
G
C
C
A
T
T
G
C
T
T
T
T
T
G
T
G
T
T
T
T
A
G
T
C
A
T
G
A
A
G
T
19000
A
T
T
T
G
T
C
C
A
T
G
C
C
T
A
T
G
T
C
C
T
G
A
A
T
G
G
T
A
T
T
G
C
C
T
A
G
G
T
T
T
T
G
T
T
C
T
A
G
G
19050
G
T
T
T
T
T
A
T
G
G
T
G
T
T
A
G
G
T
C
T
T
A
C
A
T
T
T
A
A
G
T
C
T
T
T
A
A
T
C
C
A
T
C
T
T
G
A
G
T
T
19100
A
A
T
T
T
T
T
G
A
A
T
A
A
G
G
T
G
T
A
A
G
A
A
A
G
G
G
G
T
C
C
A
G
T
T
T
C
A
A
T
T
T
T
C
T
G
C
A
T
A
19150
T
G
G
C
T
A
G
C
C
A
G
T
T
T
T
C
C
C
A
A
C
A
T
C
A
T
A
T
A
T
A
T
T
A
A
G
A
A
G
G
G
A
A
T
C
C
T
T
T
T
19200
T
C
C
A
T
T
G
C
T
T
T
T
T
T
T
G
G
T
C
A
G
A
C
T
T
G
T
C
A
A
A
G
A
T
C
G
G
A
T
G
G
T
T
G
T
A
G
A
T
A
19250
T
G
T
G
G
C
A
T
T
A
T
T
T
C
T
G
A
G
G
T
C
T
C
T
G
T
T
C
T
G
T
T
C
C
A
T
T
G
G
T
C
T
A
T
A
T
A
T
C
T
19300
G
T
T
T
T
G
G
T
A
A
A
A
G
T
A
C
C
A
T
G
C
T
G
T
G
T
T
G
G
T
T
A
C
T
G
G
A
G
G
C
T
T
G
T
A
G
T
A
T
C
19350
A
T
T
T
A
A
A
G
T
C
A
G
G
A
A
G
C
A
T
G
A
T
G
C
C
T
C
C
A
G
C
T
T
T
G
T
T
C
T
T
T
T
T
G
C
T
T
A
G
G
19400
A
T
T
G
T
C
T
T
G
G
C
T
A
T
A
T
G
G
G
C
T
T
T
T
T
T
T
T
T
T
T
T
T
T
T
T
T
T
T
T
G
G
T
T
C
C
A
T
A
T
19450
G
A
A
A
T
T
T
A
A
A
G
T
A
G
T
T
T
T
T
T
C
C
A
A
T
T
C
T
G
T
G
A
T
G
A
A
A
G
T
C
A
A
T
G
G
T
A
G
C
T
19500
T
G
A
T
G
G
G
G
A
T
A
G
C
A
T
T
G
A
A
T
C
T
A
T
A
A
A
T
T
A
C
T
T
T
G
G
G
C
A
G
T
A
T
G
G
C
C
A
T
T
19550
T
T
T
A
C
A
A
T
A
T
T
G
A
T
T
C
T
T
C
C
T
A
T
C
C
A
T
G
A
G
C
A
T
A
G
A
A
T
G
T
T
T
T
T
C
C
A
T
T
T
19600
A
T
T
T
G
T
G
T
C
C
T
C
T
C
T
T
A
T
T
T
C
A
T
T
G
A
G
C
A
G
T
G
G
T
T
T
G
T
A
G
T
T
C
T
C
G
T
T
G
A
19650
A
G
A
G
G
T
C
C
C
T
C
A
C
A
C
C
C
C
T
T
G
T
A
A
G
T
T
G
T
A
T
T
C
C
T
A
G
G
T
A
T
T
T
T
A
T
T
C
T
C
19700
A
T
T
G
T
A
G
C
A
A
T
T
G
T
G
A
A
T
G
G
A
A
G
T
T
C
A
C
T
C
A
T
G
A
T
T
T
G
G
C
T
C
T
C
T
G
T
T
T
G
19750
T
C
T
A
T
T
A
T
T
G
G
T
G
T
A
T
A
G
G
A
A
T
G
C
T
T
G
T
G
A
T
T
T
T
T
A
C
A
C
A
T
T
G
A
T
T
T
T
G
T
19800
A
T
C
C
T
G
A
G
A
C
T
T
T
G
C
T
G
A
A
G
T
T
G
C
T
T
A
T
C
A
G
C
T
T
A
A
G
G
A
G
A
T
T
T
T
G
G
G
C
T
19850
G
A
G
A
C
A
A
T
G
G
G
G
T
T
T
T
C
T
A
A
A
T
A
T
A
C
A
A
T
C
A
T
A
T
C
A
T
C
T
G
C
A
A
A
C
A
A
A
G
A
19900
C
A
A
T
T
T
G
A
C
T
T
C
C
T
C
T
C
T
T
C
T
T
A
T
T
T
G
A
G
T
A
T
C
T
T
T
T
A
T
T
T
A
T
T
T
C
T
C
T
T
19950
G
C
C
T
G
A
T
T
G
C
C
C
T
G
G
C
C
A
G
A
A
C
T
T
C
C
A
A
T
A
C
T
A
T
G
T
T
G
A
A
T
A
G
G
A
G
T
G
G
T
20000 |
var(19952):[A:0.01]
G
A
G
A
G
A
G
G
G
C
A
T
C
C
T
T
G
T
C
T
T
G
T
G
C
C
G
G
T
T
T
T
C
A
A
A
G
G
G
A
A
T
G
C
T
T
C
C
A
G
20050 |
var(20027):[A:0.01]
C
T
T
T
C
A
C
C
C
A
T
T
C
A
G
T
A
T
G
A
T
A
T
T
G
G
C
T
G
T
G
G
G
T
T
T
G
T
T
A
T
A
G
A
T
A
G
C
T
C
20100 |
var(20089):[C:0.29]
T
T
A
T
T
A
T
T
T
T
G
A
G
A
T
A
T
A
T
T
C
C
A
T
C
A
A
T
A
C
C
T
A
G
T
T
T
A
T
T
G
A
G
A
G
A
T
T
T
T
20150
A
G
C
A
C
A
G
C
T
C
C
A
G
T
G
T
G
C
A
G
C
T
C
C
C
A
A
A
A
A
G
A
T
C
A
A
C
G
C
A
G
A
A
G
G
T
G
G
G
T
20200 |
REPEAT
G
A
T
T
T
C
T
G
C
A
T
T
T
C
C
A
A
C
T
G
A
G
G
T
A
C
C
C
A
G
C
T
C
A
T
C
T
C
T
T
T
G
A
G
A
C
T
G
G
T
20250
T
A
G
A
C
A
G
T
G
G
G
T
G
C
A
G
C
C
A
A
C
A
G
G
G
G
G
C
A
A
G
C
C
G
A
A
G
C
A
G
G
G
T
A
G
G
G
T
G
T
20300
C
A
C
C
T
A
A
C
C
T
G
G
G
A
A
G
T
G
C
A
A
G
T
T
G
T
C
A
G
G
A
A
A
C
T
T
C
C
T
C
C
C
C
T
A
G
C
C
A
A
20350
G
G
G
A
A
G
C
C
A
C
G
A
G
G
G
A
C
T
G
T
G
C
C
C
T
G
A
G
G
A
A
A
A
G
T
G
C
A
T
T
C
T
G
G
T
C
C
A
G
A
20400 |
var(20379):[A:0.01]
T
A
C
T
A
T
G
C
T
T
T
T
C
C
C
A
G
T
C
T
T
T
G
C
C
A
C
C
G
G
C
A
G
A
C
C
A
G
G
A
G
A
T
T
C
C
C
T
C
G
20450 |
var(20428):[T:0.01]
G
G
T
G
C
C
T
A
C
A
C
C
A
C
C
A
G
G
G
C
C
C
T
G
G
G
T
T
G
C
A
A
G
C
A
C
A
A
A
A
C
T
G
G
G
T
G
G
C
T
20500
G
T
T
T
G
G
G
C
A
G
A
C
A
C
T
G
A
G
A
T
A
G
C
T
G
C
A
G
G
A
T
T
T
T
C
T
T
T
T
T
A
A
A
C
C
C
C
A
G
T
20550
G
G
T
G
C
C
T
G
G
G
A
C
A
C
C
A
G
C
A
A
G
A
C
A
G
A
A
C
C
C
T
T
C
A
C
T
C
C
C
C
T
G
G
A
A
A
A
G
G
G
20600
G
C
T
G
A
A
G
C
T
A
G
G
G
A
A
C
C
A
A
G
T
G
G
T
C
T
A
G
C
T
C
A
G
T
G
G
A
T
C
C
C
A
C
C
C
C
C
A
T
A
20650
G
A
G
C
C
C
A
G
C
A
A
G
C
T
G
A
G
A
T
C
C
A
C
T
G
G
C
T
T
G
A
A
A
T
T
C
T
C
C
T
T
G
C
C
A
G
C
C
G
A
20700 |
NOT SCANNED
G
C
A
G
T
C
T
G
A
A
G
T
C
A
A
C
C
C
G
G
G
A
T
G
C
T
C
G
A
G
C
T
T
G
G
T
A
G
G
G
G
G
A
G
G
G
G
T
G
T
20750
C
T
G
C
C
A
T
T
A
C
T
G
A
G
G
C
T
T
G
A
G
T
A
G
G
T
G
C
T
T
T
T
C
C
C
T
C
A
C
A
A
T
G
C
A
A
A
C
A
A
20800
A
G
C
C
A
C
T
A
G
G
A
A
C
T
G
G
G
T
G
G
A
G
C
C
C
A
C
C
G
C
A
G
C
T
C
C
A
C
A
A
A
G
C
C
C
C
T
G
T
A
20850
G
C
C
A
G
A
C
T
G
C
C
T
C
T
C
T
A
G
A
T
T
C
C
T
C
C
T
C
T
C
T
G
G
G
C
A
G
G
G
C
A
T
C
T
C
T
T
A
A
A
20900
G
A
A
A
G
G
C
A
G
C
A
G
C
C
C
C
A
G
T
C
A
C
G
G
G
C
T
T
A
T
A
T
A
T
A
A
A
A
T
T
C
C
C
T
C
T
A
T
C
T
20950
G
G
G
A
C
A
G
A
G
C
A
C
C
T
G
G
G
A
G
A
A
G
G
G
G
C
A
G
C
T
G
T
G
G
G
C
G
C
A
G
C
T
T
C
A
G
C
A
G
A
21000
C
T
T
A
A
A
C
T
A
T
C
C
T
G
C
C
T
G
C
T
G
G
C
T
C
T
G
A
A
G
A
G
G
G
C
A
G
T
G
G
A
T
C
T
C
C
T
A
G
C
21050
A
C
C
A
T
T
C
T
C
A
A
G
C
T
C
T
G
C
T
A
A
G
G
G
A
C
A
G
A
C
T
G
C
C
T
C
C
T
T
A
A
G
T
G
G
G
T
C
C
C
21100
T
G
A
C
T
C
C
C
G
T
G
C
C
T
C
C
T
G
A
C
T
G
G
G
A
G
A
C
A
C
C
T
C
A
C
A
G
C
A
G
G
G
T
T
C
A
A
C
A
G
21150
A
C
A
C
C
T
C
A
T
G
C
A
G
G
A
G
A
G
T
T
C
T
G
G
C
T
G
G
C
A
T
C
T
G
G
T
G
G
G
T
G
C
C
C
C
T
C
T
G
G
21200
A
A
T
G
A
A
G
C
T
T
C
C
A
G
A
G
G
A
A
G
G
A
A
C
A
G
G
C
C
G
C
A
A
T
C
T
C
T
G
C
T
G
T
T
C
T
G
C
A
G
21250
C
C
A
C
T
G
C
T
G
G
T
G
A
T
A
C
C
T
A
G
G
C
A
A
A
C
A
G
G
G
T
C
T
G
G
A
G
T
G
G
A
C
C
T
C
C
A
G
C
A
21300
A
A
C
T
C
C
A
G
C
A
G
A
C
C
T
G
C
A
G
C
T
G
A
G
G
G
G
C
C
T
G
A
C
T
G
T
T
A
G
A
A
G
A
A
A
A
A
C
C
T
21350
A
C
A
A
A
C
A
G
A
A
A
G
G
A
A
T
A
G
C
A
T
C
A
A
C
A
T
C
A
A
C
A
A
A
A
A
G
G
A
T
G
T
C
C
A
C
A
C
A
A
21400
A
A
A
C
C
C
C
A
T
C
T
G
A
A
A
G
G
C
A
C
C
A
A
C
A
T
C
A
A
A
G
A
C
C
A
A
A
G
G
T
A
G
A
T
A
A
A
T
C
C
21450
A
C
G
A
A
G
A
T
G
A
G
G
A
A
A
A
A
C
A
A
G
T
G
C
A
A
A
A
A
G
G
C
T
G
A
A
A
A
T
T
C
C
A
A
A
A
C
C
C
A
21500
G
A
A
T
G
C
C
T
C
A
T
C
T
C
C
T
C
C
A
A
A
G
G
A
T
C
A
TG
T
T
T
A
C
T
T
T
T
A
A
T
C
T
A
T
A
T
G
T
G
21550 |
REPEAT
T
T
T
A
T
A
T
A
T
T
T
A
A
A
G
T
G
G
G
T
T
T
C
A
T
G
T
A
G
A
C
A
A
C
A
T
A
T
A
G
T
T
G
G
T
T
C
T
T
G
21600
T
T
A
C
T
T
G
A
T
C
T
A
C
T
G
T
G
T
C
A
A
T
T
T
C
A
A
T
C
T
T
T
T
A
A
T
T
A
A
T
A
C
A
T
T
T
A
G
A
T
21650
C
A
T
T
T
G
C
G
T
T
A
A
A
A
G
T
G
A
T
T
A
C
T
G
A
T
A
T
A
T
A
G
T
C
A
T
G
T
G
T
C
A
T
T
T
A
A
C
A
A
21700 |
REPEAT
C
A
G
G
A
A
T
G
C
A
T
T
A
T
G
A
G
A
A
A
T
G
C
A
T
T
G
T
T
A
G
A
T
A
A
T
T
T
T
G
T
C
A
T
T
G
T
G
C
A
21750
A
A
C
A
T
C
T
T
A
G
C
G
T
G
T
A
C
A
T
A
C
A
T
A
A
A
C
C
T
A
G
A
T
A
T
T
A
T
A
G
C
C
T
A
C
T
A
C
A
C
21800
A
C
C
T
A
A
G
C
T
T
A
T
G
G
T
A
T
A
G
G
C
T
A
T
T
A
C
T
T
T
G
A
T
G
C
T
A
C
C
A
A
A
A
C
C
T
G
T
A
C
21850
A
T
T
A
T
T
G
T
A
G
T
T
T
A
C
T
A
A
A
T
A
C
T
A
A
T
T
A
C
A
A
C
A
C
A
G
T
G
A
T
A
T
T
G
G
T
G
T
A
T
21900
C
T
A
A
A
C
A
T
A
T
C
T
G
A
G
C
A
C
A
G
A
A
A
A
G
A
T
A
A
A
G
T
A
A
A
A
A
T
A
T
G
G
T
A
T
T
A
T
A
A
21950
T
C
T
T
A
T
G
G
G
A
C
C
A
T
C
A
T
T
G
T
A
T
A
T
G
C
T
C
T
C
C
A
A
C
A
T
T
G
A
C
T
T
A
A
A
T
G
T
C
A
22000
T
T
A
T
G
A
C
A
T
G
T
G
T
G
A
C
T
G
T
A
G
T
T
A
G
A
T
T
A
G
T
A
T
C
T
A
C
C
A
T
AGCGGTTG
G
G
22050 |
REPEAT
|
REPEAT
T
T
G
C
C
T
G
G
G
T
G
T
T
T
G
C
A
A
G
A
T
A
A
A
T
T
T
A
C
A
A
A
T
A
A
T
T
C
A
A
G
T
C
C
A
C
T
T
T
C
22100
A
C
G
T
G
A
C
G
T
C
A
T
A
C
C
A
C
T
T
C
A
T
G
G
G
T
A
G
T
A
T
G
A
G
T
A
C
C
T
G
A
T
A
A
T
A
G
C
A
A
22150
A
T
T
A
T
T
T
A
T
A
A
T
A
C
T
T
T
C
C
T
T
C
C
A
T
T
T
C
T
T
G
T
A
T
C
A
T
T
A
T
T
G
T
C
A
T
T
C
A
T
22200 |
NOT SCANNED
T
T
C
A
A
T
T
T
T
G
T
G
T
C
A
G
C
A
T
A
C
A
T
A
A
T
C
A
A
A
T
A
C
A
T
T
A
T
A
G
A
T
A
T
T
A
T
T
T
T
22250
A
A
A
A
A
C
A
G
T
T
A
T
G
T
C
T
T
A
G
A
T
T
A
A
G
A
A
T
A
A
G
A
A
A
A
G
T
A
A
T
A
A
T
T
T
A
T
A
T
T
22300
T
T
A
T
G
C
T
C
A
C
T
T
A
T
T
T
C
T
C
C
T
C
C
A
A
T
G
T
T
T
T
C
C
T
T
G
C
T
T
T
A
A
G
T
A
G
A
T
C
T
22350
G
A
G
T
T
T
C
T
G
A
T
T
T
A
T
A
T
T
A
T
T
T
T
A
T
C
T
T
T
C
T
G
T
A
A
A
G
A
A
C
T
C
C
T
T
T
T
A
A
C
22400
A
C
C
T
T
G
C
A
A
G
G
C
T
G
A
T
C
T
A
A
A
G
G
C
A
A
A
A
C
A
T
T
T
C
T
T
T
C
A
G
T
T
T
C
A
T
T
T
C
T
22450
C
A
G
A
G
G
A
A
G
T
T
T
T
A
T
T
T
C
T
C
C
T
T
C
A
T
G
T
T
A
G
A
T
G
G
A
T
A
A
A
T
A
C
A
C
A
G
G
G
T
22500 |
REPEAT
A
T
G
G
G
G
A
A
G
G
T
A
T
T
T
T
T
T
C
C
T
C
T
G
T
A
T
T
C
T
T
T
T
G
G
G
A
T
T
T
T
T
T
T
C
C
T
T
T
G
22550
T
C
T
G
T
G
A
T
T
T
T
C
T
A
T
A
G
T
T
T
T
A
A
A
A
T
G
A
C
A
T
G
A
C
T
A
G
G
T
G
T
A
A
C
T
T
T
T
T
G
22600
G
G
C
A
T
T
T
A
T
A
C
A
A
C
T
T
G
T
T
A
T
T
C
T
A
T
G
G
A
C
T
T
C
C
A
G
G
A
T
C
T
G
T
G
G
T
T
T
G
T
22650
T
G
T
C
T
G
A
T
A
C
T
A
A
T
T
T
G
G
G
G
A
A
A
T
T
C
T
C
G
G
T
T
G
T
T
A
T
T
G
T
T
T
C
A
A
A
T
A
T
T
22700
T
C
T
T
T
A
G
T
C
T
C
T
A
T
T
T
C
T
C
C
T
T
C
T
A
G
T
G
A
T
T
C
C
A
T
T
A
T
G
T
A
T
A
T
G
C
T
A
T
A
22750
C
C
T
T
T
T
T
T
A
G
T
T
G
G
C
C
C
A
C
A
G
T
T
T
T
T
T
G
A
T
A
C
T
T
T
G
T
T
C
T
G
A
T
T
T
T
T
T
T
G
22800
T
C
T
T
T
G
T
T
A
T
T
T
T
T
A
T
T
T
G
C
T
T
T
T
T
A
G
T
T
T
T
G
C
A
G
A
T
T
T
T
A
A
T
T
C
A
T
A
T
A
22850
T
C
C
T
G
A
A
T
C
T
C
A
G
A
T
A
T
C
C
T
G
T
T
T
T
C
A
G
T
C
T
T
G
T
G
C
A
G
T
A
T
A
C
T
G
A
T
G
T
G
22900
T
T
T
A
C
C
A
A
A
G
G
C
A
T
T
C
T
T
C
A
T
T
T
C
T
G
C
T
A
C
G
A
T
G
T
T
G
T
G
A
C
A
T
T
A
T
A
A
T
T
22950
T
T
T
T
T
A
A
T
G
A
A
A
T
T
T
T
T
A
T
C
T
G
T
C
T
G
C
T
T
A
C
A
T
T
G
C
T
C
T
G
T
T
C
T
T
G
T
G
T
G
23000
C
T
T
C
T
T
T
A
T
T
T
T
A
C
C
A
C
T
A
G
A
A
C
A
C
T
T
A
G
C
A
T
A
T
T
A
A
T
C
A
C
A
G
T
T
G
T
T
T
T
23050
A
A
A
T
T
C
T
C
A
G
T
C
C
A
A
T
A
A
A
T
C
C
A
A
C
A
T
C
C
T
T
T
C
T
G
T
A
T
C
T
G
A
G
T
T
T
G
G
T
T
23100
C
T
G
A
T
T
C
T
T
G
C
T
C
T
G
T
C
T
C
T
T
C
A
A
A
A
T
T
A
T
A
T
A
T
A
T
T
T
T
T
T
T
T
C
T
T
T
T
A
G
23150
A
T
G
A
C
T
G
G
T
A
A
T
A
T
A
T
T
C
T
G
G
A
T
A
T
C
C
A
G
A
C
A
T
A
A
T
G
T
A
T
T
G
A
G
T
T
T
T
G
T
23200
A
A
A
A
C
C
T
G
C
T
A
T
A
C
A
T
A
G
G
C
C
T
T
C
A
A
T
A
A
T
T
G
T
T
G
C
T
A
A
G
G
T
G
T
G
G
G
A
G
A
23250
G
G
A
G
A
G
G
C
T
T
T
T
T
T
T
T
T
T
T
T
T
T
T
T
T
T
G
C
C
T
C
T
G
G
A
C
T
G
T
A
A
C
C
T
T
C
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