RIPK1 Color FASTA
The longest form of insertion/deletion sites is shown in the FASTA sequence and contain a '-' as the alternate allele in the variation tag.
*Display courtesy of
GeneSNPs
GATGTGGGTA TTTCTGGAAT ACAAAACATC CATAGCCCTC CTTTTACTCT
50
CAAAGCAAAA CACAGACACG CACATTCACA TGCACACACC AGTGTGTCCG
100
TGTCC
T
G
T
T
G
G
T
T
T
G
C
A
T
G
G
A
G
T
T
T
C
T
G
T
T
T
T
G
C
C
A
C
G
A
A
G
C
T
T
T
T
T
G
C
C
150 |
REPEAT
A
G
C
C
C
T
T
T
T
C
C
C
A
A
A
G
T
G
T
T
T
G
T
A
C
C
A
T
T
T
T
A
T
A
C
T
C
C
C
A
C
C
A
G
T
G
A
T
G
T
200
T
T
G
A
G
A
G
G
T
C
T
G
G
T
T
G
C
T
T
C
A
C
A
T
G
T
T
T
G
C
C
A
G
T
G
T
T
T
G
G
T
G
T
A
T
T
A
G
T
C
250
T
T
T
T
T
A
G
T
T
T
T
G
G
A
T
A
T
C
C
T
G
G
T
A
G
T
T
G
T
G
T
A
G
T
G
G
T
G
T
C
T
C
C
T
T
G
T
G
G
T
300
T
C
T
CCATGGG TTTTTATTCT ATATTTCAGT TTGGGGA
G
A
A TGAATGAATG
350 |
var(338):[A:0.38]
|
var(339):[T:0.02]
GAAGAAAAGA AGGGAGGAAG GATGAAGCAA ATAGCTGTGC TTTGAGATCT
400
GACACTGTAT ACTTCACAGC CCTGATGGAC ATTCTCCAAA TTCTACTCCT
450
TTTTCACATT TTCTTCTTAG AGTTTGCATT GT
C
C
T
T
T
T
T
A
T
A
T
T
C
T
T
C
A
G
500 |
var(483):[T:0.41]
|
REPEAT
A
T
T
C
C
T
T
C
T
T
T
T
G
T
T
C
A
T
A
A
T
T
A
C
T
T
A
A
A
C
C
T
A
T
T
C
A
T
T
T
T
C
T
A
A
T
G
C
C
T
550
T
T
C
A
G
T
T
G
T
T
A
A
T
T
T
A
C
T
G
A
A
G
T
T
C
T
T
T
G
G
T
G
C
T
T
A
C
T
A
G
T
G
C
T
G
C
T
T
G
C
600
T
G
T
A
G
C
T
G
C
A
G
G
G
T
C
T
G
T
C
T
C
A
C
A
G
T
G
A
A
T
T
T
T
T
T
C
T
T
T
T
G
T
G
T
T
T
T
A
T
A
650
A
T
T
T
T
G
G
A
A
A
G
G
G
A
G
C
T
C
A
T
G
T
T
A
A
A
T
T
T
G
T
A
T
T
T
G
T
A
G
G
A
A
T
T
C
T
G
T
C
T
700
G
G
C
C
T
G
G
C
T
T
G
A
G
G
T
T
G
T
T
G
T
T
T
G
C
T
T
T
A
G
C
C
T
A
T
A
A
C
C
T
C
A
G
G
A
T
G
G
C
A
750
T
C
A
G
C
C
T
G
T
G
A
C
C
A
C
T
T
C
C
T
G
T
G
T
A
A
A
A
G
T
T
C
A
T
A
G
T
T
T
A
G
G
C
G
A
T
C
C
T
C
800
T
C
A
A
T
T
C
A
A
A
G
T
C
T
G
T
A
T
C
T
A
T
T
T
C
A
A
G
A
C
A
G
G
C
C
C
A
A
G
G
T
T
A
T
A
A
A
T
T
T
850
G
C
A
C
A
A
A
C
T
T
T
T
T
T
T
T
T
T
T
T
T
T
T
T
T
A
A
T
A
C
C
T
T
G
T
G
C
C
C
A
G
T
C
C
A
A
G
A
C
A
900
A
A
T
A
T
G
T
T
T
G
T
T
T
G
C
C
A
T
G
G
G
C
T
G
C
T
T
T
T
T
T
T
C
T
A
G
T
T
C
A
T
C
C
T
T
T
C
A
T
C
950
A
A
A
G
G
GTTGC ACATTGAGCA GTGCCGTGTT AAGGGGGGAT TCTTCATTCT
1000
ACCTTCTTTT CTTGTATTCC TTGACCTCAG CTGGGCTTTA AACCTTGACT
1050
TCTGGATGGC GAGGTTGGCA CTCCCCTGTG TGAGCTACTG CCTGCCTCCG
1100
GTG
C
T
C
T
G
T
T
T
C
T
G
T
C
C
C
T
A
A
A
G
T
T
C
T
T
T
T
C
C
T
T
T
C
C
A
C
G
G
A
G
T
T
T
T
G
G
T
1150 |
REPEAT
|
var(1121):[G:0.34]
A
T
G
C
A
T
T
T
C
A
A
T
G
A
A
T
G
T
T
T
G
T
A
T
T
A
T
G
T
T
G
T
C
C
A
A
C
A
T
A
C
T
T
G
T
G
T
C
C
T
1200
T
T
A
T
A
G
C
T
G
G
A
G
G
G
T
T
C
T
T
A
A
A
A
T
T
T
T
C
T
A
A
T
G
C
T
C
C
A
T
A
T
T
G
C
C
A
G
A
A
A
1250
T
A
A
A
A
AGGCT GAGGGAATAA ATATTATAGT CTTCTCTGAT TCTTAAAAAT
1300
ATGAAAAATA GCTCATCAGA TGACTGTAAG TCTATCCTCA GAAATCCAAG
1350
GCACACCAAG CATGTGGTGG AATGTTAACA AAAGTTTTTA AAAATGATCT
1400
TTTCT
G
C
C
A
G
G
T
A
C
A
A
T
G
G
C
T
C
A
C
A
C
C
T
G
T
A
A
T
C
T
C
A
G
C
A
C
T
T
T
G
G
G
A
G
G
1450 |
REPEAT
C
T
G
A
G
G
T
G
G
G
A
G
G
A
T
C
C
C
T
T
G
A
T
C
T
T
A
G
G
A
G
T
T
T
G
A
G
A
C
C
A
G
C
C
T
G
G
G
C
A
1500
A
C
A
T
A
G
T
G
A
G
A
T
C
C
C
C
C
G
G
C
C
C
C
C
C
C
A
T
C
T
C
T
A
C
A
A
A
T
A
A
T
T
A
A
A
A
A
A
T
C
1550
A
G
C
T
G
G
T
C
A
C
G
G
T
G
G
G
G
T
G
C
A
C
C
T
G
T
G
G
T
C
C
C
A
G
C
T
A
C
T
C
A
A
G
G
A
G
G
C
T
G
1600
A
G
G
G
A
G
G
A
G
G
A
T
T
G
C
C
T
G
A
G
C
C
C
A
G
G
A
G
G
T
C
G
A
G
G
C
T
C
C
A
G
T
G
A
G
C
T
A
T
G
1650
A
T
T
G
T
G
C
C
A
C
T
G
C
A
C
T
C
C
A
G
C
C
T
G
A
C
T
G
A
C
A
A
A
G
T
G
A
G
A
C
C
C
T
G
T
C
T
C
C
A
1700
A
A
G
G
A
G
A
A
A
A
A
A
A
A
A
A
A
CAT ATATATATAT ATATATATAT ATATAGTCTT
1750
GCCCTGAGGT TTTCTCTCTG TTTTCTTTAC AGGGTACAGC TCTGCCGGGG
1800
GGGGAAAAAG TGGTACCATT TTGGGCGTTC TTGAGCTTCA GA
A
T
G
C
A
A
C
C
1850 | Exon 1
M Q P 3
A
G
A
C
A
T
G
T
C
C
T
T
G
A
A
T
G
T
C
A
T
T
A
A
G
A
T
G
A
A
A
T
C
C
A
G
T
G
A
C
T
T
C
C
T
G
G
A
G
A
1900
D M S L N V I K M K S S D F L E 19
G
T
G
C
A
G
A
A
C
T
G
G
A
C
A
G
C
G
G
A
G
G
C
T
T
C
G
G
G
A
A
G
G
T
G
T
C
T
C
T
G
T
G
T
T
T
C
C
A
C
1950 |
var(1926):[T:0.16]
S A E L D S G G F G K V S L C F H 36
A
G
A
A
C
C
C
A
G
G
G
A
C
T
C
A
T
G
A
T
C
A
T
G
A
A
A
A
C
A
G
T
G
T
A
C
A
A
G
G
G
G
C
C
C
A
A
C
T
G
2000
R T Q G L M I M K T V Y K G P N C 53
C
A
T
T
G
A
GTGA GTAGGGAGCA GGGGTGGGTG GGCTAAGTTC TGAGCGGGAT
2050
I E 55
GGGGACGTTG GCTGTTGTGG AGCCGTTGGC TGCTGCGGAG CCGTTGGTGG
2100
GTAGAGTGAG AGGGAGCCTG CCAAGATGTC AGGGTGACGA TGGCTCTTCG
2150
GATTGTTATT GTCGCTGATG TGGACTCTGA GACTGGGTAG TGAAGGACTC
2200
TCACAGCTGG TAAGTAACAG AAGAGACATG AACAAGAAGG AAATAGAGAA
2250
AGACAAAGAG ATAAGTGTGG TGGGGGGACA ATGAAAAGGA AACAGGAGGA
2300
TGGGTGAAGA CAGACCTATT CACTCGCTTC ACATTTTCAG TGAGGACCAG
2350
CCCTAAGTAT AAAAATGAAA AGGCAGTTCA TTCCTGAGAG GTTCTGAGAG
2400
CCTTCCCTTT AAAGCAACCA GTAGAGTGGT TTCACCTCTC TCCCTCCTTT
2450
GTCAGAGTGG TTTTGAGAGA GGCTGTTTTT TTTTTTTTTA ATCGTTCTGT
2500
CCAGCACGGT CTTTTTTCAG GTTACCTTGC TGCTGTTCAT GTACTTTTCA
2550
TTCATTGATT CATTCATTCC TTCATTGATT TACATTTTTG GAGCATGCAC
2600
TGCCAGTTAC TGGGCAGGAG TACTGTGAGG AAGTGAGAAA CCGCTCTGCC
2650
TTCTAACGCT TCTGGCCTGT GCCTGGAAGA GATCGGTACA GACCCAAGCA
2700
TGACCCCAGC AC
G
TGGGAGT GATGTGTTGG AGGTGTGCAC CAGGCTCTTG
2750 |
var(2713):[A:0.05]
AGGCGCTGGC TCTGCCAGCC TCAGCATAGC ACCTTTCCTG CCCACAG
G
C
A
2800 | Exon 2
H 56
C
A
A
C
G
A
G
G
C
C
C
T
C
T
T
G
G
A
G
G
A
G
G
C
G
A
A
G
A
T
G
A
T
G
A
A
C
A
G
A
C
T
G
A
G
A
C
A
C
A
2850
N E A L L E E A K M M N R L R H 72
G
C
C
G
G
G
T
G
G
T
G
A
A
G
C
T
C
C
T
G
G
G
C
G
T
C
A
T
C
A
T
A
G
A
G
G
A
A
G
G
G
A
A
G
T
A
C
T
C
C
2900
S R V V K L L G V I I E E G K Y S 89
C
T
G
G
T
G
A
T
G
G
A
G
T
A
C
A
T
G
G
A
G
A
A
G
G
G
C
A
A
C
C
T
G
A
T
G
C
A
C
G
T
G
C
T
G
A
A
A
G
C
2950
L V M E Y M E K G N L M H V L K A 106
C
G
A
G
GTAGAG AGGGCCCCTC CGCAC
G
GGGA TCCCCAGCGC TTGGGCCCTG
3000 |
var(2976):[A:0.01]
E 107
GCTGTCTGTT ATGGCTCCCC TTGGGGTGTT TGTTTGCAGC TCGTTAGCAT
3050
A
AAATTTGCA AATTGCTTGG TAGTTTGAA
T
T
T
T
C
T
T
T
T
C
C
T
T
T
T
T
T
T
A
T
A
3100 |
var(3051):[C:0.17]
|
REPEAT
G
A
G
A
C
A
A
G
G
T
C
T
T
G
C
T
A
T
G
T
T
G
C
C
C
A
G
G
C
T
G
A
A
C
T
C
C
A
A
C
A
C
C
T
G
G
T
C
T
C
3150
A
A
G
T
G
A
T
C
C
T
C
C
C
A
C
C
T
C
A
G
C
C
T
C
T
C
A
A
G
T
A
G
C
T
G
G
G
A
T
T
A
C
A
G
G
C
TGGA
3200
TTTCCTGAAG TCAGTTTCTC CTTAAAACAT CTATGCCTTG ATT
G
G
G
C
T
C
C
3250 |
REPEAT
G
T
G
G
G
T
C
A
C
T
T
C
T
G
T
A
A
T
C
T
C
A
G
C
A
C
T
T
T
T
G
G
C
A
G
G
A
G
G
A
T
C
A
C
T
T
G
A
G
C
3300
C
T
T
G
G
T
G
C
T
C
A
A
G
A
C
C
A
G
C
C
T
G
G
A
T
A
A
C
A
C
A
G
T
G
A
A
A
T
C
C
C
C
T
C
T
C
T
A
C
A
3350
A
A
A
A
A
T
A
A
A
A
GGTGCATGTG AACAGAGCAA GACCCTGTCT CTGAAAAAAA
3400
GAGAA
A
ATCT TCCTTGCCTT TTACTGCCCT GAGAGTGGTC TCTTCATCCT
3450 |
var(3406):[G:0.02]
CTCGATCCTG TGGACAGTCC TCCATAGTCT GTGTCTTAGG AATGTGATTG
3500
GCTGTTTACC ATACCTGTCC GCTGCTCTGC AATCTACAGT TCAGAGACAA
3550
GCCCTGTCTT CATGATGCAG ACATCATCTG ATGTAGAGTA TATGCATGAT
3600
GGGATGACAT TAAATATGGA TTAATGAAAG GATATACACT ATAAATGACC
3650
GTGAGAGCAG ATAGAATATT AGTGGTTGCA CTTTGATACC ATTCAACAAA
3700
GTTTTATTTT AAATTAAATA TAGAAATTAT TGGCAACAAC ACTGGATAGG
3750
ATTTAAAACA AAAATAAAAA TTGTTTACCA AAGTCAAATG ATTTGAAAAC
3800
ATTTTTAAAA GCTTATGTGC CTGTTAAGAT GAAGGCCTTG CGCTAGTTGC
3850
TCATGAATCA ATAGCTAATA TGA
C
GTAGGA GAGTAAAAGG AGGCAGATAG
3900 |
var(3874):[T:0.01]
CTAAATAAGT GGTA
T
GGTGT GATGGGG
T
T
T
T
T
T
T
T
T
T
T
T
C
T
T
T
T
G
T
A
A
G
A
3950 |
var(3915):[C:0.03]
|
REPEAT
|
NOT SCANNED
G
A
A
C
A
A
G
G
T
C
T
C
A
C
T
G
T
G
T
T
G
C
C
C
A
G
G
C
T
G
G
A
G
T
G
C
A
G
T
G
G
C
A
C
A
A
T
C
A
T
4000
A
G
T
G
C
A
C
T
G
C
A
G
G
C
T
T
G
A
A
C
T
C
C
T
G
G
C
C
T
T
A
A
A
T
G
A
T
C
C
T
C
T
C
A
C
C
T
C
A
G
4050
C
C
T
C
C
T
G
A
G
T
A
G
C
T
G
G
G
A
C
T
A
T
G
G
G
C
A
T
G
A
G
C
C
A
C
T
G
C
A
C
C
C
A
G
C
T
G
T
G
T
4100
G
G
T
G
G
T
A
T
T
T
T
T
T
T
T
T
T
T
A
G
A
G
G
A
G
T
C
T
C
G
C
T
C
T
G
T
C
G
C
C
C
A
G
G
C
T
G
G
A
G
4150 |
REPEAT
|
var(4129):[T:0.02]
|
var(4138):[A:0.01]
T
G
C
A
A
T
G
G
T
G
C
A
A
T
C
T
C
G
G
C
T
C
A
C
T
G
C
A
A
C
C
T
C
C
A
C
C
T
C
C
C
T
G
G
T
T
C
A
A
G
4200
C
A
A
C
T
C
T
C
C
T
G
C
C
T
C
A
G
C
C
T
C
T
T
G
A
G
T
A
G
C
T
G
G
G
A
T
T
A
C
A
G
G
C
G
C
C
T
A
C
C
4250
A
C
C
A
T
G
C
C
T
G
G
C
T
A
T
T
T
T
T
T
T
A
A
T
T
T
T
T
A
G
T
A
G
A
G
A
C
A
A
G
T
T
T
T
C
A
C
C
A
T
4300
G
T
T
G
G
T
C
A
G
G
C
T
G
G
T
C
T
C
G
A
A
C
T
C
C
T
G
A
C
C
T
C
G
T
G
A
T
C
C
G
A
C
T
G
C
C
T
T
G
G
4350
C
C
T
C
C
C
G
A
A
G
T
T
C
T
G
G
G
A
T
T
A
C
A
G
G
C
A
T
G
A
G
C
C
A
C
C
G
T
T
C
C
C
A
G
C
T
GATG
4400
GTGTTTTGAT AGACATACTC ATTG
C
T
G
A
G
G
G
A
G
T
A
C
A
C
A
T
G
A
G
A
G
G
C
A
C
C
4450 |
REPEAT
C
A
C
T
C
A
G
C
C
T
G
G
A
A
T
A
G
A
C
A
G
A
A
A
A
G
G
C
T
T
C
C
A
A
T
G
T
G
A
A
G
G
A
C
A
T
G
T
A
G
4500
A
C
G
T
T
T
T
G
A
A
G
C
A
G
A
G
A
A
T
T
A
G
A
G
A
A
C
A
A
G
T
G
T
T
C
T
A
G
G
C
A
G
A
G
A
G
A
A
T
A
4550
C
C
A
T
G
T
A
G
A
G
A
C
T
G
C
C
A
A
A
T
T
T
G
G
G
G
A
A
C
T
G
T
A
A
A
T
T
C
C
T
G
G
G
T
T
T
G
G
C
T
4600
A
G
A
G
C
A
T
A
G
A
T
T
G
C
A
C
A
G
G
G
T
A
T
G
G
G
G
A
G
G
G
G
T
G
G
C
G
G
G
A
T
A
T
G
G
CTGCC
4650
TTTATGGCAA ATACTCCCAC TTTTCCACTT TCTTCTCCCA CCCCACAATT
4700
GCCAAGCCAA CAGACATCTC ACAAAAATAC CCTTGGGAAG GAGAAGAGGT
4750
GATCACTTAT ACGCATGGTA TTATAGTTTG ATCAGATTGC TCTCCACCCC
4800
AGAACTAGAG AAGATCAGCT GTTTGAAGTA AACATTTTGA TTGGGAAATA
4850
AGTCTTTGGT CTCCCATCCA AGTACTAACC AGGCCCAACC CTGCTTAGCT
4900
TCTGAGATGA GAGAGAAATC ATTGGGGACA TGAGGCATTG TGCAAGATGA
4950
GGGAAAGTTC AGGTGCACCT GTTTGGACTC AGTCAGGGCA TCAGGAGGAC
5000
CTGAGAGAGA AGCAGAAAGA GAGGAGAGAG GGGGACCAAC TTTGCTTACT
5050
CAGAAGTTTT TCCTAAGTCC AAAGGTATAC CAAGGAAGAA GAGAAAACAT
5100
CTTTTCTGAT ACTTTCTGTA TGGTGGTGAT CAAGCTATTA ACAGTGTAGC
5150
TCTGCTACGT TATGTCATAA ATATGGTTTG AGGGGGAATC TCACTTCTAT
5200
CATTAAAATT TTTTTCCTGT TAACCAACGA CCAAAATACA TATACATTTT
5250
TAGGAAACAT CTTGTTTGTA TACTGATTTT TTATTGTTAA GCAAAACTGT
5300
AATTTAACCA CTATAATAGA AACTGGAATT GTTTCTGTTA GTATTGATGC
5350
TCACATAACA AGAATACAAT TATAAGAACC AGTGACCTGA GACTCTACAG
5400
AAGCCTGAAG TATCTGCTAC CAGGTCATCA AATAGATATT AATTCACTTA
5450
AGCGTAGTTT TAACA
T
CATG TTTATCTCAG ATTTTTCTAT GATTGTAATC
5500 |
var(5466):[A:0.01]
AGTGTGAACA TGTTCCCTTG TATTCTTTTT TCTCTTAATG TTATTTTACA
5550
CGCGACATTT GCATGGCATT GTTCATGTCC TTAATGTAAA CTTAGTATGA
5600
TGTCGTGTGA GTATCCCACA GAAACTGCTT GCTCGTATAT TTATTC
A
T
C
C
5650 |
REPEAT
A
T
T
C
A
T
T
C
A
A
C
A
A
G
C
A
T
T
C
C
A
G
G
T
A
C
A
A
T
C
C
T
A
G
G
T
T
C
T
A
A
A
G
A
T
A
C
A
G
T
5700
C
C
T
A
A
A
T
A
A
T
A
T
A
T
A
T
T
T
T
T
G
T
T
C
T
C
A
A
G
G
A
G
C
T
T
A
ATTT TATAGTATTT
5750
TATGCATTAC CAAATTATTG TGGGATTTTT GTTTTTACAC TAACAAAATA
5800
CAACACGAAT ACCCTCTGCC CCCCCCCGAA TGAAATCTTT CTTGTTTCCC
5850
AGTGACAGCA GTACTGTGGT GCACCTGCTG GAAGGAAACC TGGTAACCTT
5900
CTCCTCAGGC TCAGATCCCA CCACCCTTTC ATGAAACAGT TGCTTTGGCC
5950
TATTTGATAA CCTTTCCATT TCATAGACTT AATATCACTT GTTTTAG
A
T
G
6000 | Exon 3
M 108
A
G
T
A
C
T
C
C
G
C
T
T
T
C
T
G
T
A
A
A
A
G
G
A
A
G
G
A
T
A
A
T
T
T
T
G
G
A
A
A
T
C
A
T
T
G
A
A
G
G
6050
S T P L S V K G R I I L E I I E G 125
A
A
T
G
T
G
C
T
A
C
T
T
A
C
A
T
G
G
A
A
A
A
G
G
C
G
T
G
A
T
A
C
A
C
A
A
G
G
A
C
C
T
G
A
A
G
C
C
T
G
6100
M C Y L H G K G V I H K D L K P 141
A
A
A
A
T
A
T
C
C
T
T
G
T
T
G
A
T
A
A
T
G
A
C
T
T
C
C
A
C
A
T
T
A
A
G
GTAAA CCATCATCGG
6150
E N I L V D N D F H I K 153
TAGGCTTCCA GAAAGTTGGG TGATTTTAGT TTTAATTCTC CAATGTAAAT
6200
CCATTCTCGT ACATTGGAGA AGCTAAAGGA AGACCTAGCT CAGCTTATAA
6250
CTGTTGATGA TGGTGCCGAA AGGCTCTACC GGTGATTGAG AGGAAG
G
CTG
6300 |
var(6297):[A:0.02]
CAGGCTTGAT GGGATCAGGA GATAACTGTC AGGATAACTC ATATCTTTTG
6350
GGGGAGGAGT GGA
G
TTGAAT GGGGTAGATG AGAAGACCTC TTTCCTAGAC
6400 |
var(6364):[A:0.34]
TGTGTTTTTT CCTCTGTTAG AAACATTTAG AAACATTCAA GGGTTGCCCT
6450
TTTCATCCTG GAATGGGCCA TTGGTGTCAT AATGTTCTCC AGGAAATCTG
6500
TGTCACCAAG ACTCTCCTCC TCTGGAAATG CAGGGGAATG TGAAGGTGTG
6550
TGCGGAAAAT CCTTAGAGTT CAGATATGGC CTAAGAGTGA GATCAGC
G
G
C
6600 |
REPEAT
C
G
G
G
T
G
C
A
G
T
G
G
C
C
C
A
C
G
C
C
T
G
T
T
A
T
C
T
C
A
G
C
A
C
T
T
T
G
G
G
A
G
G
C
T
G
A
G
G
T
6650
G
G
G
C
G
G
A
T
C
A
C
C
T
G
A
G
G
T
C
G
G
G
A
G
T
T
C
G
A
G
A
C
C
A
G
C
C
T
G
A
C
C
A
A
C
A
T
G
G
A
6700
G
A
A
A
C
C
C
C
A
T
C
T
C
T
A
C
T
G
A
A
A
A
T
A
C
A
A
A
A
T
C
A
G
C
C
G
G
G
C
G
T
G
G
T
G
G
T
G
C
A
6750
T
G
C
C
T
G
T
A
A
T
T
C
C
A
G
C
T
A
C
T
C
G
G
G
A
G
G
C
T
G
G
G
G
C
A
G
G
A
G
A
A
T
C
G
C
C
T
G
A
A
6800
C
C
G
G
G
G
A
G
G
T
G
G
A
G
G
T
T
G
T
G
G
T
G
A
G
C
C
G
A
G
A
T
T
G
T
G
C
C
A
T
C
G
C
A
C
T
C
C
A
G
6850
C
C
T
G
G
G
C
A
A
C
A
A
G
A
G
C
G
A
A
A
C
T
C
T
G
C
C
T
T
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
6900
A
A
A
A
A
A
A
A
A
A AAAAAAAAAA AAAATCAGCA GTGCATCAAA AACCTCTACT
6950
TTGAAATTTT GTTTTATATT TGTATTCGAT TGTTTACTTC TGTCTGTATT
7000
TTAAAAATCA GTTTCCTTTG AACA
C
ATTCT TTCCATTGTC GTAAAGGGAA
7050 |
var(7025):[T:0.06]
CAAGGGAAAG GGATTTTTCT TTTGTTCATT CAAGGGCAGG ATTTAGCTAG
7100
GGGGAGTGTC ATATCTAATT GGCTTCCGCA GCAGGAATCC AAGCACAAGA
7150
ATCCAAAAGG GGAAGCGGAA GGGGAAGCAG CCCTGGGGGA GGCACCCAGG
7200
AGCTGCTGAC ACAGGGGCCT CTCATCACCA GCAGGTTCTG C
G
TCTAGCGC
7250 |
var(7242):[A:0.02]
TTTGTCCTAG TCTTGGACAA AGGGCTGGGA ATAAAAATTC CTTATTCATA
7300
ACCTATCTTC AAATTCATGA CTTCCCTCTT ATGTCGTGGG TTAGAATCTG
7350
TGAATTTTAG GTACTCATGT GCCACAGTTC ATCCCCACAT GCTTGCTTGG
7400
ATTCCTGGAG GCAGAAGTGG AACTGGCACC TATATTCTCT TCTGAACTGT
7450
GCTGCCCTGT CATTTTGCCC TGCCAGCACT GTTCTTGTTC TGTGTCTGAC
7500
CTTGCTATTT TTCTCTCTGC TTTTTTGTCT GTTTTTCTCC TCCTTTCCAC
7550
CCTATCTCCT CTTAGGTTCA GGCTACAGCT CAAAACAAGC AACACTGCAG
7600
TCCTTATCCT CAGTGTGTCT TTGGGATCCT TGGACACTCG CATCCATGGG
7650
CCTCTGGACG CCATTTGGGG AAATAGAAGG TGTAGTATTT AGCCACTGTC
7700
TGCTGCATAA ATGTGCAGAG AAGAAAATAA CCATTTTCCC CCCAAGCCCT
7750
AGAAATAGTT GAAAAACATA CGCAGAGTCA ATGGGGAATG AGAATAAATA
7800
TGTTTGGTTG TTACTGTTCT TGTCAGAAAC ATCTTCCGCT TTTCCCCTCC
7850
CCCTTACTGC ATAAGGAATA CGATACCAGA ATTTCATGTG AACGTTTCCT
7900
GGGCGACATT TTACAAATGG CTGAGGAGAC ACACAGTTTC TATGAGTCTG
7950
TTGAGAAGTC GCTGTTTTGA ACCTGCCCAG TGCAACCATT TCTGGAAAAT
8000
TTACCGTACC TTATGTATAA TGGATAAGCC CAAAATTGAA AGTCAGATCT
8050
GATTTGCTTA CGGCCTTCAC CAAACAATCC CAGTGGCTCA ATGTCTTTCG
8100
CAG
A
T
C
G
C
A
G
A
C
C
T
C
G
G
C
C
T
T
G
C
C
T
C
C
T
T
T
A
A
G
A
T
G
T
G
G
A
G
C
A
A
A
C
T
G
A
A
8150 | Exon 4
I A D L G L A S F K M W S K L N 169
T
A
A
T
G
A
A
G
A
G
C
A
C
A
A
T
G
A
G
C
T
G
A
G
G
G
A
A
G
T
G
G
A
C
G
G
C
A
C
C
G
C
T
A
A
G
A
A
G
A
8200
N E E H N E L R E V D G T A K K 185
A
T
G
G
C
G
G
C
A
C
C
C
T
C
T
A
C
T
A
C
A
T
G
G
C
G
C
C
C
G
A
G
C
A
C
C
T
G
A
A
T
G
A
C
G
T
C
A
A
C
8250
N G G T L Y Y M A P E H L N D V N 202
G
C
A
A
A
G
C
C
C
A
C
A
G
A
G
A
A
G
T
C
G
G
A
T
G
T
G
T
A
C
A
G
C
T
T
T
G
C
T
G
T
A
G
T
A
C
T
C
T
G
8300
A K P T E K S D V Y S F A V V L W 219
G
G
C
G
A
T
A
T
T
T
G
C
A
A
A
T
A
A
G
G
A
G
C
C
A
T
A
T
G
A
A
A
G
T
A
A
G
G
C
A
T
T
A
C
T
T
A
C
T
T
8350 |
REPEAT
A I F A N K E P Y E 229
T
C
C
A
C
T
G
C
C
G
T
C
C
C
C
T
C
A
G
C
A
T
C
T
A
C
A
C
G
C
A
C
T
G
T
G
C
C
T
G
G
A
A
C
T
A
A
T
A
G
8400 |
var(8395):[C:0.03]
G
T
G
C
C
C
A
G
T
A
A
A
T
T
T
T
T
G
T
T
G
A
A
T
G
A
A
T
G
A
G
T
AATCCCAT TTAGGAATCA
8450
GTGATCATAG GATGAATAGG AACCTC
G
ATA GTGTGTCATT AGCTGGAGAG
8500 |
var(8477):[A:0.02]
GTGCTGTGAA ATTCCAGGGT TCTTCCTAGA CAGGAAAGTT GATTGTTTCT
8550
GCTTGTGAGG ACTTAGCCTT TCACACTACA AGGCATACAC TTCATACTTT
8600
CACTCATTCA CTTGC
T
C
C
T
T
C
A
T
T
C
A
A
G
A
A
T
T
A
T
T
T
C
T
T
T
T
C
A
G
T
C
C
C
T
A
8650 |
REPEAT
C
T
G
T
G
G
G
C
A
C
T
T
G
A
G
T
C
G
G
C
A
T
T
G
G
G
A
A
T
A
T
A
A
A
G
A
T
G
A
G
T
A
A
GTCGTGG
8700 |
var(8667):[A:0.04]
CTTGTGTAGG ATAGAGACAC TCTGCAGTTT GTTAAGTGCA TAAACTGATG
8750
GATGTTGTC
C
T
A
C
A
T
A
C
T
C
T
T
C
T
T
G
G
G
T
G
A
T
C
A
T
C
A
G
C
T
C
C
C
A
T
G
G
T
T
T
G
8800 |
REPEAT
A
T
G
A
T
C
A
T
C
T
C
T
T
T
G
C
A
A
A
T
G
C
T
T
C
T
T
A
A
A
T
C
T
G
T
G
T
C
T
C
T
G
G
C
T
C
T
G
G
A
8850
A
T
G
G
A
T
A
T
C
C
A
C
T
T
G
T
C
T
T
A
C
A
G
T
C
A
G
A
T
C
C
A
T
C
G
C
A
G
G
T
A
C
C
A
G
A
G
G
A
A
8900
C
C
T
C
C
A
A
A
G
C
A
G
C
A
T
C
C
C
C
C
A
A
A
C
A
C
A
T
C
C
T
G
T
C
G
A
C
A
C
T
G
T
C
C
T
G
C
A
G
C
8950
T
C
G
C
C
C
C
G
C
T
T
C
A
C
C
C
C
T
C
T
T
C
A
T
A
T
G
C
T
T
G
G
G
A
A
G
T
G
G
C
A
T
C
G
C
C
A
T
C
C
9000
T
T
T
T
A
C
C
A
A
G
T
T
G
T
T
G
C
C
C
A
A
T
A
A
G
A
A
A
C
T
T
C
A
G
A
G
T
C
A
T
C
C
C
A
G
A
C
T
C
G
9050
C
C
C
T
T
G
C
C
C
C
T
C
T
C
T
C
C
C
A
C
A
T
T
C
T
A
T
C
A
G
A
T
C
T
C
A
A
A
A
C
C
T
G
T
G
A
A
T
T
C
9100 |
var(9100):[G:0.07]
A
A
G
A
T
A
T
A
T
G
T
A
T
G
A
C
T
C
A
A
G
A
T
A
T
A
T
C
T
G
C
A
A
C
C
C
A
T
C
T
G
C
C
T
T
T
C
T
C
T
9150 |
var(9107):[C:0.01]
|
var(9134):[A:0.01]
G
T
C
T
C
C
A
C
T
G
G
C
C
T
C
T
G
C
T
C
A
G
T
T
C
A
A
A
C
C
C
T
C
C
T
C
G
T
T
T
C
T
G
C
A
G
C
A
G
G
9200 |
var(9184):[:0.09]
C
T
C
C
T
T
C
C
A
C
C
G
T
C
C
A
C
C
A
T
T
C
A
T
G
T
G
G
C
A
G
C
C
A
A
A
A
T
G
G
T
C
G
T
C
C
T
A
A
A
9250 |
var(9211):[T:0.02]
A
G
G
C
A
C
A
T
G
C
A
A
C
C
C
T
C
T
C
C
C
T
C
A
C
A
T
A
T
T
G
G
A
A
A
T
C
C
T
T
C
C
C
A
G
A
T
G
C
T
9300
C
T
G
T
G
G
T
C
T
T
C
A
G
G
A
T
G
A
A
G
T
T
C
G
A
A
T
T
C
C
T
C
A
G
C
G
T
G
G
A
A
T
A
A
A
A
G
G
C
C
9350
T
T
C
A
T
G
T
T
C
T
G
G
C
C
T
T
T
G
C
T
T
C
T
C
T
A
C
T
G
G
C
C
T
C
G
T
C
C
C
T
A
A
C
C
C
T
C
C
C
T
9400 |
NOT SCANNED
T
C
T
T
T
G
T
C
A
G
T
G
T
G
C
A
G
T
T
A
C
A
C
T
G
A
G
G
A
A
T
T
T
G
T
G
G
G
A
T
G
C
G
T
C
A
T
G
A
T
9450
C
T
C
T
G
T
A
A
C
T
T
C
T
A
G
T
C
T
G
T
T
G
A
T
A
T
C
C
T
G
C
T
T
C
T
C
T
T
C
C
T
G
G
A
G
T
C
C
T
C
9500
C
T
C
C
T
T
A
A
G
T
C
T
C
C
C
T
T
T
C
C
C
A
T
T
C
T
T
T
A
C
C
T
G
C
T
A
A
T
T
T
T
T
C
T
G
G
A
C
T
C
9550
A
A
C
A
A
A
G
C
C
T
T
C
C
T
G
G
A
C
C
T
T
T
T
T
A
G
T
C
A
G
G
T
T
T
G
T
G
C
T
A
C
T
G
G
A
A
C
C
C
C
9600
T
T
G
T
A
C
A
T
C
C
T
T
T
T
T
T
T
T
T
T
T
T
T
T
T
T
C
C
C
G
T
G
A
G
A
C
A
G
A
G
T
C
T
C
A
T
T
C
T
G
9650 |
REPEAT
|
var(9629):[T:0.06]
T
C
G
C
C
A
G
G
T
T
G
G
A
G
T
G
C
A
G
T
G
G
T
G
C
A
G
T
C
T
C
G
G
C
T
C
A
C
T
G
C
A
G
C
C
T
C
C
A
C
9700
C
T
C
C
C
A
G
G
T
T
C
A
A
G
C
A
A
T
T
C
T
T
C
T
G
C
C
T
C
A
G
C
C
T
C
C
C
G
A
G
T
A
G
C
T
G
G
G
A
C
9750
T
A
C
A
G
G
T
G
C
A
C
A
C
C
A
C
C
A
T
G
C
C
C
A
G
C
T
A
A
T
T
T
T
T
A
T
A
T
T
T
T
T
A
G
T
A
G
A
G
A
9800 |
var(9755):[A:0.04]
C
G
G
G
G
T
T
T
C
A
C
C
A
T
G
T
T
G
G
C
C
A
G
G
A
T
G
G
T
C
T
T
G
A
T
C
T
C
T
T
G
A
C
G
T
C
A
T
G
A
9850
T
C
C
G
C
C
T
G
T
C
T
C
A
A
C
C
T
C
C
C
A
A
A
G
T
G
C
T
G
G
G
A
T
T
A
C
A
G
G
T
G
T
G
A
T
C
C
A
C
C
9900
A
T
G
C
C
C
A
G
C
C
T
C
A
T
C
C
T
T
C
T
T
G
A
A
T
A
G
C
A
A
T
G
A
T
C
A
C
T
C
T
G
T
G
T
T
T
T
A
A
G
9950 |
REPEAT
|
var(9914):[G:0.10]
T
C
A
C
T
C
T
C
A
T
T
A
A
A
C
T
G
A
G
C
T
C
C
T
A
A
A
G
A
C
A
A
G
G
A
C
T
G
C
C
C
T
G
T
A
T
T
TGC
10000
TTTTGCACAT GGAGCATGCC ATTGGCCTTG CCCACATAAT CTTTTTGTTC
10050
CATCAGCAGG CAGCTTTGTC GAGAATTTTG TTT
T
A
T
C
T
G
C
A
G
A
C
A
T
T
A
A
G
10100 |
NOT SCANNED
A
T
A
T
T
G
T
T
T
G
G
T
C
A
T
C
T
C
T
G
T
A
G
T
G
G
A
A
T
A
T
G
T
C
A
G
C
T
C
C
T
T
G
T
C
A
T
A
A
G
10150
G
C
C
A
T
T
C
C
A
C
T
C
T
A
T
G
G
A
A
T
G
A
G
G
C
A
G
C
T
G
T
A
C
C
A
G
A
G
G
C
T
G
A
G
A
A
A
A
A
T
10200
G
A
G
C
A
GTATT GTTCAAGTTC TGTCACCTTC CTGCCTGAGA GAGGAGCAAG
10250
ACCTGAAAGA A
A
GTCTTTGC TTTGTAG
A
T
G
C
T
A
T
C
T
G
T
G
A
G
C
A
G
C
A
G
T
T
G
10300 |
var(10262):[C:0.05]
| Exon 5 |
var(10289):[A:0.02]
|
var(10298):[C:0.02]
N A I C E Q Q L 237
A
T
A
A
T
G
T
G
C
A
T
A
A
A
A
T
C
T
G
G
G
A
A
C
A
G
G
C
C
A
G
A
T
G
T
G
G
A
T
G
A
C
A
T
C
A
C
T
G
A
10350
I M C I K S G N R P D V D D I T E 254
G
T
A
C
T
G
C
C
C
A
A
G
A
G
A
A
A
T
T
A
T
C
A
G
T
C
T
C
A
T
G
A
A
G
C
T
C
T
G
C
T
G
G
G
A
A
G
C
G
A
10400
Y C P R E I I S L M K L C W E A 270
A
T
C
C
G
G
A
A
G
C
T
C
G
G
C
C
G
A
C
A
T
T
T
C
C
T
G
GTA AGAGCATCTT TTCTGACTGT
10450
N P E A R P T F P 279
GTAGGATGCA TCCTGTGTGG TGATTTTCCT AGTAACATAT TGTTAGGAAC
10500
TTGGTTTGAA TCCTCAG
A
A
A
A
C
T
G
A
G
T
T
C
G
A
C
T
T
G
A
C
T
T
G
T
G
G
T
T
T
T
A
A
A
10550 |
NOT SCANNED
C
T
G
A
T
T
T
T
C
T
A
G
A
T
T
T
C
A
A
A
C
A
T
G
T
T
A
T
T
C
A
G
T
G
C
A
A
A
G
A
A
G
C
C
C
T
C
T
C
T
10600
C
T
C
A
A
A
A
G
C
A
T
G
A
T
G
G
C
A
C
A
T
A
A
G
G
C
C
T
T
C
T
T
G
T
T
T
C
C
T
T
T
T
T
T
T
G
T
A
A
T
10650 |
REPEAT
T
A
A
C
T
T
T
T
T
A
A
C
T
T
G
G
G
T
T
T
A
A
A
T
A
T
A
C
G
T
A
A
C
A
T
G
A
A
A
T
T
T
A
A
C
A
T
T
G
T
10700 |
REPEAT
A
A
C
T
G
T
T
T
T
C
A
A
G
T
G
C
A
C
T
G
T
T
C
A
G
G
G
G
C
A
G
T
A
A
G
T
A
C
A
G
T
C
C
C
A
T
A
G
T
A
10750 |
REPEAT
C
A
T
T
C
A
C
T
T
T
C
C
A
T
C
G
T
C
T
C
T
C
T
C
C
C
T
G
C
C
C
C
T
G
G
C
A
G
C
C
C
T
C
A
T
C
C
T
A
C
10800 |
var(10792):[C:0.33]
|
var(10793):[T:0.33]
T
T
T
C
T
G
T
C
T
C
T
G
T
G
A
A
T
T
T
A
A
C
T
G
C
A
C
T
G
G
G
T
G
C
C
T
T
A
T
A
T
A
T
A
A
G
T
G
G
A
10850 |
var(10843):[:0.89]
A
T
C
A
T
A
C
A
G
T
A
T
T
T
G
T
C
C
T
T
T
T
G
T
G
T
C
T
G
G
C
T
T
A
T
T
C
C
A
C
T
T
G
G
C
A
T
G
A
T
10900 |
var(10885):[C:0.39]
G
T
C
C
T
C
G
A
G
G
T
T
C
A
T
C
T
G
T
G
T
T
G
T
A
G
C
A
T
A
T
G
T
C
A
G
A
A
T
T
T
C
T
T
T
C
C
T
T
T
10950
T
C
A
A
G
G
C
T
G
A
A
T
A
A
T
A
T
T
C
C
A
T
T
G
T
A
T
G
A
A
T
G
G
A
G
T
G
C
A
T
T
T
T
G
T
T
T
A
T
C
11000
C
A
T
T
C
G
T
C
C
G
T
C
T
A
T
G
G
G
C
A
C
T
T
A
G
G
T
G
G
C
T
T
T
G
A
C
C
AGC CTTCTTGCTT
11050 |
var(11009):[T:0.01]
|
var(11010):[A:0.01]
CTTCACTTCT TTTATTTCCA TCCCCTCCCT TGTTTAGCTG GCATCTTT
A
G
11100 |
var(11099):[:0.66]
A
A
A
G
T
A
T
T
T
T GCCGTCTAGA TTGGCCTTGT CATACAGGGA TGAGGAAAGG
11150
TGCCGGGATG T
T
T
G
C
T
G
A
G
C
A
G
T
A
T
T
C
T
A
T
G
G
T
G
T
G
G
A
T
G
T
A
C
C
A
C
G
G
T
T
11200 |
REPEAT
T
G
G
T
T
A
A
C
T
A
C
T
C
A
C
T
C
C
T
T
G
A
A
A
G
A
C
T
T
G
T
T
T
C
C
A
G
T
T
C
T
T
A
A
C
T
G
T
T
G
11250
G
G
A
C
T
A
A
T
G
C
A
G
C
T
G
T
A
A
A
T
A
T
T
T
G
T
G
G
A
C
A
T
G
T
T
T
T
T
G
T
G
T
G
A
A
T
A
T
A
A
11300 |
var(11274):[C:0.40]
G
T
C
T
T
C
A
T
T
T
C
T
C
T
G
G
A
G
T
A
A
T
A
C
C
C
A
G
G
G
G
T
A
C
A
A
T
A
G
C
T
A
G
G
T
T
G
T
A
T
11350
G
G
T
A
G
T
T
T
C
A
T
G
T
A
C
A
G
T
T
T
A
T
T
T
T
A
A
A
A
A
T
T
C
C
C
T
A
A
C
A
T
T
T
T
C
C
C
A
G
A
11400
G
G
G
G
C
T
G
T
G
C
C
A
T
T
T
T
A
T
G
T
T
C
G
G
T
G
T
C
C
G
A
G
T
G
A
T
G
C
A
G
G
T
T
C
T
T
G
T
A
T
11450 |
var(11422):[T:0.01]
C
C
T
C
A
C
C
A
G
C
A
T
G
G
G
G
T
ACC CAGGCTCCTC ACA
C
T
T
C
T
G
C
T
T
A
G
T
C
A
G
C
T
11500 |
REPEAT
A
C
A
A
A
T
T
T
A
T
T
T
G
A
G
T
A
T
T
C
C
C
A
C
A
A
G
C
C
C
C
A
C
T
T
C
A
G
G
T
T
T
G
G
T
A
A
T
T
C
11550
G
T
T
A
G
A
A
A
G
A
C
T
C
A
C
A
T
A
A
C
T
C
A
A
G
A
A
A
A
C
A
T
T
T
T
A
C
T
T
A
C
G
T
C
T
C
C
C
C
T
11600
T
T
T
A
C
T
G
C
A
G
T
G
G
G
T
A
C
A
A
T
T
C
A
G
A
A
A
C
A
G
C
C
A
A
A
T
G
G
A
A
C
A
G
A
T
G
T
A
C
A
11650 |
var(11641):[G:0.37]
A
G
G
T
G
A
G
G
T
A
T
G
G
G
A
G
G
A
G
G
G
T
G
T
A
T
A
G
A
A
C
T
T
C
C
A
T
A
G
C
C
T
T
T
C
A
A
G
A
C
11700
A
C
A
C
T
G
C
A
T
T
C
C
A
G
T
G
C
T
T
C
T
G
T
G
T
G
T
T
C
A
G
C
A
A
C
C
T
G
A
A
G
C
T
C
T
C
C
A
A
G
11750 |
var(11705):[C:0.37]
|
var(11738):[C:0.36]
C
C
T
C
A
C
C
G
T
T
T
A
A
G
G
T
G
A
T
T
T
A
T
G
G
A
A
G
T
T
C
C
A
T
T
A
C
A
T
A
G
G
C
A
T
G
A
C
T
G
11800 |
var(11791):[C:0.36]
A
C
T
A
A
A
T
C
A
T
G
G
T
C
A
T
T
G
G
T
G
C
T
T
G
A
G
C
T
T
A
A
T
C
T
C
C
A
G
T
C
C
C
T
C
T
C
T
C
C
11850
T
C
A
C
T
G
G
A
A
G
T
C
A
A
A
G
G
T
G
G
A
G
C
T
G
A
A
A
G
T
C
C
C
A
A
C
C
T
T
C
T
A
A
T
T
A
T
A
G
C
11900
T
T
G
G
T
C
T
T
T
C
T
G
G
T
T
G
C
T
A
G
C
C
C
C
C
A
T
T
C
T
G
A
A
G
T
T
G
C
C
T
A
G
TTTTCTGA
11950
CCCCACCCAA AAGACACTCT TAGAAGACTC CAAGGATTTT AGGTGCTACC
12000
TGCCATGAAC AAAATCAAA
C
C
T
T
C
C
T
G
A
T
T
C
T
C
C
A
A
G
G
T
G
T
C
T
T
C
T
T
T
T
A
12050 |
REPEAT
|
var(12023):[C:0.15]
T
T
G
T
T
T
C
C
T
T
T
C
T
G
T
T
T
A
G
A
G
A
A
C
T
T
T
C
C
T
T
A
A
T
C
A
T
T
C
T
T
T
T
A
G
G
A
T
A
T
12100 |
var(12058):[T:0.07]
|
var(12083):[G:0.01]
G
T
C
T
G
AACT
C
T
G
T
C
A
T
T
C
T
A
A
A
A
T
T
T
T
T
T
T
C
C
T
T
A
T
A
G
G
G
A
A
G
G
T
G
T
T
A
T
12150 |
REPEAT
|
var(12131):[T:0.03]
T
T
T
T
C
T
C
T
T
G
C
T
G
C
T
T
T
C
A
A
G
A
C
T
T
T
G
T
C
T
T
T
A
T
T
T
T
T
C
A
G
A
G
A
T
T
T
A
G
T
12200 |
var(12173):[A:0.06]
T
G
T
T
A
T
T
T
A
T
C
T
T
G
G
T
G
T
G
G
A
T
T
C
C
T
T
T
G
G
G
T
T
T
A
T
T
C
T
G
T
T
T
A
G
G
T
T
T
T
12250
G
C
T
C
A
G
C
T
T
C
T
T
A
A
A
T
C
T
G
T
A
G
G
T
T
T
A
T
G
C
C
T
C
T
T
A
A
A
C
C
A
T
A
T
T
T
G
G
G
A
12300 |
var(12300):[G:0.41]
A
G
C
T
T
T
C
A
G
C
C
A
T
T
A
T
T
T
C
T
G
T
A
A
G
T
A
C
T
T
T
T
T
A
A
C
C
C
C
C
A
C
C
C
T
C
T
T
T
C
12350
T
C
T
T
T
T
C
T
T
T
C
T
G
G
A
A
T
T
C
T
G
A
C
A
A
C
A
T
A
A
A
A
A
C
T
A
T
A
T
C
T
T
T
G
G
T
T
A
T
G
12400 |
var(12384):[T:0.14]
G
T
T
A
T
A
G
T
C
C
C
A
C
A
G
G
T
C
C
C
T
G
A
G
G
C
T
T
T
G
T
G
T
T
T
T
T
T
T
T
G
T
T
T
T
T
T
T
T
G
12450 |
var(12432):[:0.23]
T
T
T
T
T
G
T
T
T
G
T
T
T
T
T
T
T
C
A
G
T
T
A
A
T
T
T
T
C
T
C
T
C
T
C
T
T
A
T
T
C
A
G
A
C
T
G
G
G
T
12500
A
A
G
T
T
C
T
A
T
C
A
T
T
C
T
G
T
C
T
T
C
C
A
G
T
T
C
A
C
T
G
A
T
T
T
T
T
C
T
G
T
T
T
C
T
C
C
T
C
G
12550
A
T
T
C
C
A
C
A
G
T
T
G
A
A
C
C
T
G
T
C
T
A
C
T
G
A
G
C
T
T
T
T
T
T
T
T
T
T
T
T
T
T
G
A
C
A
C
G
G
A
12600 |
REPEAT
C
T
C
T
C
A
C
T
C
T
G
T
C
G
C
C
C
A
G
G
T
T
G
G
A
G
T
G
C
A
G
T
G
G
C
G
C
A
A
G
C
T
C
T
G
C
C
T
C
C
12650
T
G
G
G
T
T
C
A
C
G
C
C
A
T
T
T
T
C
C
T
G
C
C
T
C
A
G
C
C
T
C
C
C
G
A
G
T
A
G
C
T
G
G
G
A
C
T
A
C
A
12700
G
A
C
A
C
C
C
G
C
C
A
C
C
A
C
A
C
C
T
G
G
C
T
A
A
T
T
T
T
T
T
G
T
A
T
T
T
T
T
A
G
T
A
G
A
G
A
C
G
G
12750 |
var(12749):[A:0.36]
G
G
T
T
T
C
A
C
C
G
T
G
T
T
A
G
C
C
A
G
G
A
T
G
G
T
C
T
C
C
A
T
C
T
C
C
T
G
A
C
C
T
T
G
T
G
A
T
C
A
12800 |
var(12777):[G:0.01]
|
var(12780):[T:0.08]
|
var(12800):[C:0.04]
G
C
C
C
G
C
C
T
T
G
G
C
C
T
C
C
C
A
A
A
G
T
G
C
T
G
G
G
A
T
T
A
C
A
G
G
T
G
T
G
A
G
C
C
A
C
T
G
T
G
12850 |
var(12809):[C:0.14]
|
var(12818):[G:0.04]
|
var(12824):[:0.23]
|
var(12837):[C:0.07]
|
var(12838):[A:0.04]
T
C
C
G
G
C
C
T
A
C
C
G
A
G
C
T
T
T
T
T
A
T
T
A
T
G
T
T
T
T
G
G
T
C
A
T
T
A
A
A
G
T
T
T
T
C
A
G
C
T
12900 |
REPEAT
C
T
A
A
A
A
T
T
T
A
T
A
T
T
C
T
C
C
C
C
T
T
T
T
T
T
G
C
T
G
A
G
A
C
T
T
T
C
T
A
T
T
T
T
T
C
A
T
T
T
12950
G
T
T
T
C
A
A
G
C
A
G
G
T
T
C
A
T
A
A
C
T
A
T
T
A
A
T
T
G
A
A
T
C
G
T
T
T
T
T
A
T
C
A
T
G
G
C
T
G
T
13000 |
var(12982):[C:0.03]
T
T
T
A
A
A
A
T
C
C
T
T
G
A
C
A
G
G
T
A
A
T
T
C
T
G
A
C
A
T
T
G
C
T
G
T
C
A
T
C
T
C
A
G
T
A
T
T
G
G
13050
C
A
T
C
T
A
T
T
G
A
T
T
G
T
C
T
T
A
T
T
T
C
A
T
T
C
A
G
T
T
T
C
T
G
A
T
T
C
T
T
A
A
T
G
T
A
A
T
G
G
13100
G
T
A
A
T
T
T
T
T
C
T
G
T
T
G
A
A
A
C
T
T
G
T
A
C
A
T
T
T
T
C
T
T
C
C
T
A
T
G
T
T
T
G
G
A
G
A
T
T
C
13150
T
G
T
A
T
C
C
T
C
T
T
T
A
A
G
C
C
T
T
C
T
G
T
T
T
T
A
A
C
T
G
A
A
C
T
T
T
C
C
T
G
A
C
A
C
T
G
C
T
C
13200
T
G
A
C
A
A
G
G
G
A
A
G
A
G
T
G
G
T
G
G
C
C
A
C
C
T
T
A
T
T
A
G
T
G
C
T
G
G
G
T
A
G
A
G
G
T
A
G
A
A
13250
G
T
T
C
A
G
C
C
T
C
T
C
G
A
C
T
C
A
G
C
C
C
T
T
A
T
T
G
A
C
A
C
C
T
A
A
G
G
T
C
A
G
A
G
G
C
T
C
C
T
13300
C
T
T
C
A
C
T
G
C
T
G
A
T
C
A
G
G
G
G
T
G
G
G
A
A
T
T
C
T
G
G
C
A
G
A
G
T
C
C
A
C
A
C
G
G
T
C
C
C
C
13350 |
var(13314):[A:0.01]
|
var(13315):[T:0.01]
|
var(13343):[T:0.16]
A
C
T
G
A
C
A
C
A
G
A
G
G
T
G
A
A
G
G
T
A
C
C
T
C
A
T
T
A
C
T
A
C
T
G
G
A
C
A
A
T
G
T
T
A
A
A
A
G
T
13400 |
var(13373):[T:0.15]
C
C
C
G
A
T
T
C
T
C
C
A
C
T
A
G
A
C
C
T
C
C
T
C
T
G
A
C
A
C
T
T
C
C
C
C
A
G
T
G
G
G
G
A
A
G
G
G
A
A
13450 |
var(13403):[T:0.18]
G
G
G
T
G
G
T
C
T
T
G
T
T
A
C
T
G
C
C
A
T
G
T
G
G
G
G
C
A
A
A
T
C
C
A
G
G
C
T
A
T
T
C
T
T
G
T
G
T
T
13500
C
T
C
C
T
G
A
C
A
C
C
A
T
G
G
G
A
G
T
G
G
A
G
G
C
G
C
T
C
A
T
T
A
T
C
A
G
C
T
G
G
C
A
G
G
T
A
G
G
A
13550 |
var(13525):[T:0.01]
C
A
G
C
C
C
T
G
G
C
T
T
C
C
T
G
T
T
G
G
G
C
C
T
T
C
T
C
T
G
A
C
A
T
T
A
C
C
C
C
G
G
T
G
G
G
G
G
T
G
13600
T
T
G
G
G
T
T
A
C
G
T
T
G
T
T
A
C
T
G
T
C
T
C
A
T
G
C
G
G
T
T
G
G
A
T
G
T
T
G
A
G
G
C
T
C
T
C
C
A
C
13650
T
T
G
G
C
C
T
T
A
G
C
T
G
C
T
G
T
G
G
G
T
G
G
G
G
T
T
G
G
A
G
C
C
A
C
A
G
G
G
T
T
T
T
T
T
C
T
G
T
G
13700 |
var(13651):[G:0.01]
G
T
G
G
T
T
G
G
C
T
G
G
A
A
C
A
G
A
G
T
G
G
T
T
G
C
T
G
A
C
T
A
A
A
A
G
T
T
T
T CTCCTATCCA
13750 |
var(13726):[T:0.07]
AGTACTAACC AGACCTGACC CT
G
CCTAACT TCCAAGATCA GACAAGTTTG
13800 |
var(13773):[A:0.01]
GGCATATTCA GGATGGCATG GCTGTAGAC
T
G
G
C
T
A
A
A
G
G
T
T
T
T
C
T
G
T
C
T
G
13850 |
REPEAT
T
C
C
C
T
T
G
C
T
G
C
C
C
C
T
T
G
C
T
T
A
G
T
T
C
T
T
T
G
G
C
T
A
G
A
A
A
G
A
G
C
A
G
G
C
T
T
T
A
G
13900 |
NOT SCANNED
T
T
G
G
A
G
A
T
T
T
T
T
T
T
T
T
A
T
C
T
G
T
G
G
C
T
C
T
T
G
A
T
G
G
T
T
T
G
A
G
G
T
T
G
C
C
A
C
C
T
13950
T
T
T
C
A
G
C
C
A
A
G
T
C
T
G
A
G
A
T
A
T
A
T
G
A
G
G
A
A
A
A
G
A
G
A
A
A
A
T
C
C
A
G
T
G
A
A
C
T
C
14000
A
C
T
A
T
C
G
T
G
T
G
T
T
T
C
A
T
C
T
G
A
T
C
C
C
G
A
G
G
T
T
T
C
C
T
G
C
T
G
G
T
C
T
G
C
C
T
C
C
T
14050
T
C
T
C
T
T
C
T
C
C
T
T
T
C
A
G
A
G
A
C
T
C
T
G
T
A
T
G
T
T
T
G
T
T
T
T
A
T
A
A
A
T
A
A
T
A
T
A
T
A
14100
G
G
A
T
G
T
T
T
T
T
G
T
T
G
T
A
C
T
T
A
G
A
A
G
G
A
A
G
A
T
T
A
A
G
A
A
A
A
A
A
G
T
A
T
G
T
C
C
A
C
14150
T
C
C
A
T
C
T
T
C
C
T
G
G
A
A
C
T
G
G
A
A
G
T
T
T
C
T
T
T
T
T
T
C
T
T
T
T
A
A
G
G
C
T
A
A
C
A
G
C
T
14200
G
T
A
A
C
C
C
A
T
T
A
C
A
C
T
A
A
A
T
C
C
T
T
C
C
T
C
T
G
A
C
T
A
T
C
C
C
A
A
T
C
T
C
T
C
A
T
A
A
A
14250
T
T
T
G
A
T
G
C
C
A
G
A
G
G
A
A
C
A
G
A
A
A
C
A
T
G
G
A
G
T
T
C
G
C
C
C
A
T
C
C
C
T
G
T
T
C
A
G
C
T
14300
G
G
A
G
A
T
G
A
A
C
T
C
A
C
A
T
C
A
G
G
G
A
G
C
A
G
T
T
T
G
T
G
T
T
G
C
A
G
C
C
A
G
A
G
A
A
A
C
T
G
14350
C
A
G
C
A
C
G
A
A
T
A
A
A
A
A
G
C
A
C
A
A
A
G
A
G
C
A
C
A
G
G
C
T
A
T
T
G
A
G
G
C
A
G
A
A
A
C
C
C
C
14400
T
G
G
T
T
T
C
C
T
G
T
G
T
T
A
G
C
C
T
A
T
C
C
C
T
T
G
T
T
C
T
G
T
C
T
A
T
T
A
A
T
C
T
T
A
T
T
A
G
T
14450
C
T
C
T
A
T
C
A
G
A
G
T
C
A
G
T
G
A
T
T
T
G
G
A
G
C
T
T
A
A
A
T
T
T
T
T
A
T
T
T
A
A
G
C
T
T
T
G
C
C
14500
C
A
C
A
G
A
T
T
G
A
G
G
T
A
A
G
T
A
A
T
T
C
A
A
A
G
A
T
A
A
T
A
G
A
T
G
G
C
T
A
A
T
A
T
T
T
T
T
A
T
14550
T
T
T
A
T
G
T
T
A
G
A
A
A
A
T
A
A
T
T
A
A
G
A
A
A
T
T
T
A
A
A
G
T
A
C
A
TTTT ACTTTTACAG
14600
279
G
C
A
T
T
G
A
A
G
A
A
A
A
A
T
T
T
A
G
G
C
C
T
T
T
T
T
A
T
T
T
A
A
G
T
C
A
A
T
T
A
G
A
A
G
A
A
A
G
T
14650 | Exon 6
G I E E K F R P F Y L S Q L E E S 296
G
T
A
G
A
A
G
A
G
G
A
C
G
T
G
A
A
G
A
G
T
T
T
A
A
A
G
GTA GGCAATATAG CAGATGCTCA
14700
V E E D V K S L K 305
AAATATTAAC ATAGCAAAAT ATATACTGTC AATCATGAAA ACCAAAACAA
14750
AGTGATTTGT TATTGAGATT TGAGGTAAGC TAGCTTGGTA AACATATAAA
14800
ACAAAATGAG CAATTGTCTG CACATATCAT CCTGTTGGCA TACTGGACCC
14850
ATTTCTCCTT CAAAACTCAT GAAATGAGAG AAAACATATA TAGCAATATG
14900
AAAACAAAAG CACAATGTCA CTGGCAAAGA TTGGAAAGTA CCATAAGTGG
14950
ATCAGCCATT TTGAGGAATT CTTGAAAGAT AGAAAGACCA CAGAATTATT
15000
CTGCTGAGAC ATATAACAGA CAAGGAATAC TAGCCCAAGA CATAATGCTG
15050
AGGAAGAAGT ACCGGAGGGG CAGTCTTGGG TCAGTGTGCA GAAGCAACAG
15100
CACAGTCACC TGGGATGTTG ACAGGGGAGT CATCTGAGAA CCTCATTTAT
15150
GCTATTTAGG AAAGTCGGCT TCTCTCCCTC CTTCCCCTGT ACTTAGCAAC
15200
AGATGGCAGC AGCATCTGCC CAAGACTGAA GCAAGGAGGT GGTTTCTGGG
15250
GTTAGAGGGG CATGACAAGG CCCAGTTAGG AACCAATCAA CTAAGAGGAA
15300
TGGAGACCAC CCCGCCCCCC TGCCAACTCT GGAATCAAGC TACTGCCATC
15350
CATCTTCCAG CAACCTACCC CATAATCATG AACAGGAGAC TACGACAAAT
15400
AAAACAGGCA GAGACTTTAA AATATAATTT AAAAAAGAG
A
T
T
A
G
A
A
T
C
A
G
15450 |
REPEAT
C
T
A
A
G
A
T
A
A
A
C
T
C
T
A
A
G
G
C
A
A
A
A
A
A
T
C
A
T
T
C
C
C
T
C
A
A
A
C
A
A
T
C
A
G
G
A
A
T
A
15500 |
var(15488):[:0.03]
T
T
T
C
A
T
A
A
T
G
A
T
A
A
A
A
G
G
C
C
C
A
A
T
T
C
A
T
C
T
G
G
A
A
A
G
T
A
T
A
A
C
C
G
C
T
T
T
A
A
15550
A
T
G
T
G
G
A
T
C
C
A
C
C
T
T
C
A
A
T
A
A
C
A
T
G
A
C
C
T
C
A
A
A
A
T
C
A
A
C
C
A
G
C
C
A
A
A
A
G
T
15600 |
var(15560):[T:0.17]
|
var(15598):[:0.17]
G
A
C
A
G
A
A
C
T
C
A
A
A
G
A
A
A
A
A
C
A
G
A
C
A
A
A
T
C
C
A
C
A
A
T
T
A
A
A
A
C
T
G
A
A
G
A
T
T
T
15650
T
A
A
T
A
C
A
C
A
T
C
T
C
T
C
T
T
C
A
A
T
T
G
A
T
A
G
A
A
C
G
A
G
C
A
A
A
C
A
A
A
A
A
T
C
A
G
T
A
A
15700
G
G
A
T
A
T
A
G
A
A
G
A
C
A
G
A
A
A
G
A
A
C
A
T
G
A
C
G
A
A
C
A
C
A
C
T
T
G
A
C
G
T
A
A
C
G
G
A
A
A
15750 |
NOT SCANNED
C
A
C
A
G
G
A
T
A
C
G
C
T
G
C
A
C
C
T
A
A
T
A
A
C
C
G
C
A
G
C
G
C
A
C
C
T
A
C
C
T
G
C
C
G
C
A
C
C
T
15800
A
G
T
A
A
C
C
G
C
A
G
A
G
C
G
C
C
T
A
C
C
T
G
C
C
G
C
A
C
C
T
A
G
T
A
A
C
C
G
C
A
G
C
G
C
A
C
C
T
A
15850
C
C
T
G
C
C
G
C
A
C
C
T
A
G
T
A
A
C
C
G
C
A
G
A
G
T
A
C
C
T
A
C
C
T
G
C
C
G
C
A
C
C
T
A
G
T
A
A
C
C
15900
G
C
A
G
C
G
C
G
C
C
T
A
C
C
T
G
C
C
G
C
A
C
C
T
A
G
T
A
A
C
C
G
C
A
G
C
G
C
G
C
C
T
A
C
C
T
G
C
C
G
15950
C
A
C
C
T
A
G
T
A
A
C
C
G
C
A
G
C
G
C
G
C
C
T
A
C
C
T
G
C
C
G
C
A
C
C
T
A
G
T
A
A
C
C
G
C
A
G
C
G
C
16000
G
C
C
T
A
C
C
T
G
C
C
G
C
A
C
C
T
A
G
T
A
A
C
C
G
C
A
G
C
G
C
G
C
C
T
A
C
C
T
G
C
C
G
C
A
C
C
T
A
G
16050
T
A
A
C
C
G
C
A
G
C
G
C
G
C
C
T
A
C
C
T
G
C
C
G
C
A
C
C
T
A
G
T
A
A
C
C
G
C
A
G
C
G
C
G
C
C
T
A
C
C
16100
T
G
C
C
G
C
A
C
C
T
A
G
T
A
A
C
C
G
C
A
G
A
G
C
G
C
C
T
A
C
C
T
G
C
C
G
C
A
C
C
T
A
G
T
A
A
C
C
G
C
16150
A
G
A
G
C
G
C
C
T
A
C
C
T
G
C
C
G
C
A
C
C
T
A
G
T
A
A
C
C
G
C
A
G
A
G
C
G
C
C
T
A
C
C
T
G
C
C
G
C
A
16200
C
C
T
A
G
T
A
A
C
C
G
C
A
G
A
G
C
G
C
C
T
A
C
C
T
G
C
C
G
C
A
C
C
T
A
G
T
A
A
C
C
G
C
A
G
C
G
C
G
C
16250
C
T
A
C
C
T
G
C
C
G
C
A
C
C
T
A
G
T
A
A
C
C
G
C
A
G
A
G
T
A
C
C
T
A
C
C
T
G
C
C
G
C
A
C
C
T
A
G
T
A
16300
A
C
C
G
C
A
G
C
G
C
G
C
C
T
A
C
C
T
G
C
C
G
C
A
C
C
T
A
G
T
A
A
C
C
G
C
A
G
C
G
C
G
C
C
T
A
C
C
T
G
16350
C
C
G
C
A
C
C
T
A
G
T
A
A
C
C
G
C
A
G
C
G
C
G
C
C
T
A
C
C
T
G
C
C
G
C
A
C
C
T
A
G
T
A
A
C
C
G
C
A
G
16400
C
G
C
G
C
C
T
A
C
C
T
G
C
C
G
C
A
C
C
T
A
G
T
A
A
C
C
G
C
A
G
C
G
C
G
C
C
T
A
C
C
T
G
C
C
G
C
A
C
C
16450
T
A
G
T
A
A
C
C
G
C
A
G
C
G
C
G
C
C
T
A
C
C
T
G
C
C
G
C
A
C
C
T
A
G
T
A
A
C
C
G
C
A
G
C
G
C
G
C
C
T
16500
A
C
C
T
G
C
C
G
C
A
C
C
T
A
G
T
A
A
C
C
G
C
A
G
C
G
C
G
C
C
T
A
C
C
T
G
C
C
G
C
A
C
C
T
A
G
T
A
A
C
16550
C
G
C
A
G
A
G
C
G
C
C
T
A
C
C
T
G
C
C
G
C
A
C
C
T
A
G
T
A
A
C
C
G
C
A
G
A
G
C
G
C
C
T
A
C
C
T
G
C
C
16600
G
C
A
C
C
T
A
G
T
A
A
C
C
G
C
A
G
A
G
C
G
C
C
T
A
C
C
T
G
C
C
G
C
A
C
C
T
A
G
T
A
A
C
C
G
C
A
G
A
G
16650
C
G
C
C
T
A
C
C
T
G
C
C
G
C
A
C
C
T
A
G
T
A
A
C
C
G
C
A
G
C
G
C
G
C
C
T
A
C
C
T
G
C
C
G
C
A
C
C
T
A
16700
G
T
A
A
C
C
G
C
A
G
C
G
C
G
C
C
T
A
C
C
T
G
C
C
G
C
A
C
C
T
A
G
T
A
A
C
C
G
C
A
G
C
G
C
G
C
C
T
A
C
16750
C
T
G
C
C
G
C
A
C
C
T
A
G
T
A
A
C
C
G
C
A
G
C
G
C
G
C
C
T
A
C
C
T
G
C
C
G
C
A
C
C
T
A
G
T
A
A
C
C
G
16800
C
A
G
C
G
C
G
C
C
T
A
C
C
T
G
C
C
G
C
A
C
C
T
A
G
T
A
A
C
C
G
C
A
G
C
G
C
G
C
C
T
A
C
C
T
G
C
C
G
C
16850
A
C
C
T
A
G
T
A
A
C
C
G
C
A
G
A
G
C
G
C
C
T
A
C
C
T
G
C
C
G
C
A
C
C
T
A
G
T
A
A
C
C
G
C
A
G
C
G
C
G
16900
C
C
T
A
C
C
T
G
C
C
G
C
A
C
C
T
A
G
T
A
A
C
C
G
C
A
G
C
G
C
G
C
C
T
A
C
C
T
G
C
C
G
C
A
C
C
T
A
G
T
16950
A
A
C
C
G
C
A
G
A
G
C
G
C
C
T
A
C
C
T
G
C
C
G
C
A
C
C
T
A
G
T
A
A
C
C
G
C
A
G
A
G
C
G
C
C
T
A
C
C
T
17000
G
C
C
G
C
A
C
C
T
A
G
T
A
A
C
C
G
C
A
G
A
G
C
G
C
C
T
A
C
C
T
G
C
C
G
C
A
C
C
T
A
G
T
A
A
C
C
G
C
A
17050
G
A
G
C
G
C
C
T
A
C
C
T
G
C
C
G
C
A
C
C
T
A
G
T
A
A
C
C
G
C
A
G
C
G
C
G
C
C
T
A
C
C
T
G
C
C
G
C
A
C
17100
C
T
A
G
T
A
A
C
C
G
C
A
G
C
G
C
G
C
C
T
A
C
C
T
G
C
C
G
C
A
C
C
T
A
G
T
A
A
C
C
G
C
A
G
C
G
C
G
C
C
17150
T
A
C
C
T
G
C
C
G
C
A
C
C
T
A
G
T
A
A
C
C
G
C
A
G
C
G
C
G
C
C
T
A
C
C
T
G
C
C
G
C
A
C
C
T
A
G
T
A
A
17200
C
C
G
C
A
G
C
G
C
G
C
C
T
A
C
C
T
G
C
C
G
C
A
C
C
T
A
G
T
A
A
C
C
G
C
A
G
A
G
C
G
C
C
T
A
C
C
T
G
C
17250
C
G
C
A
C
C
T
C
G
G
A
A
C
C
G
C
A
G
A
G
C
G
C
C
T
A
C
C
T
G
C
C
G
C
A
C
C
T
C
G
G
A
A
C
C
G
C
A
G
A
17300
G
C
G
C
C
T
A
C
C
T
G
C
C
G
C
A
C
C
T
C
G
G
A
A
C
C
G
C
A
G
A
G
C
G
C
C
T
A
C
C
T
G
C
C
G
C
A
C
C
T
17350
C
G
G
A
A
C
C
G
C
A
G
A
G
C
G
C
C
T
A
C
C
T
G
C
C
G
C
A
C
C
T
C
G
G
A
A
C
C
G
C
A
G
A
G
C
G
C
C
T
A
17400
C
C
T
G
C
C
G
C
A
C
C
T
C
G
G
A
A
C
C
G
C
A
G
A
G
C
G
C
C
T
A
C
C
T
G
C
C
G
C
A
C
C
T
C
G
G
A
A
C
C
17450
G
C
A
G
A
G
C
G
C
C
T
A
C
C
T
G
C
C
G
C
A
C
C
T
C
G
G
A
A
C
C
G
C
A
G
C
G
C
G
C
C
T
A
C
C
T
G
C
C
G
17500
C
A
C
C
T
C
G
G
A
A
C
C
G
C
A
G
C
G
C
G
C
C
T
A
C
C
T
G
C
C
G
C
A
C
C
T
C
G
G
A
A
C
C
G
C
A
G
C
G
C
17550
G
C
C
T
A
C
C
T
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C
C
G
C
A
C
C
T
C
G
G
A
A
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C
A
G
C
G
C
G
C
C
T
A
C
C
T
G
C
C
G
C
A
C
C
T
C
G
17600
G
A
A
C
C
G
C
A
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C
G
C
G
C
C
T
A
C
C
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C
C
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C
A
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A
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T
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A
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C
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C
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C
G
C
G
C
C
T
A
C
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17650
T
G
C
C
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C
A
C
C
T
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C
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C
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C
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C
C
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C
A
C
C
T
A
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T
A
A
C
C
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C
17700
A
G
A
G
C
G
C
C
T
A
C
C
T
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C
C
G
C
A
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A
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A
17750
C
C
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C
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C
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C
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A
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17800
C
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C
A
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17850
A
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17900
C
C
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C
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17950
C
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C
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18000
T
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C
C
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C
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C
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C
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C
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18050
A
C
C
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C
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C
A
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C
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C
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C
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G
C
A
C
C
T
A
G
T
A
A
C
18100
C
G
C
A
G
C
G
C
G
C
C
T
A
C
C
T
G
C
C
G
C
A
C
C
T
A
G
T
A
A
C
C
G
C
A
G
C
G
C
G
C
C
T
A
C
C
T
G
C
C
18150
G
C
A
C
C
T
A
G
T
A
A
C
C
G
C
A
G
C
G
C
G
C
C
T
A
C
C
T
G
C
C
G
C
A
C
C
T
A
G
T
A
A
C
C
G
C
A
G
C
G
18200
C
G
C
C
T
A
C
C
T
G
C
C
G
C
A
C
C
T
A
G
T
A
A
C
C
G
C
A
G
A
G
C
G
C
C
T
A
C
C
T
G
C
C
G
C
A
C
C
T
C
18250
G
G
A
A
C
C
G
C
A
G
A
G
C
G
C
C
T
A
C
C
T
G
C
C
G
C
A
C
C
T
A
G
G
A
A
C
C
G
C
A
G
A
G
C
G
C
C
T
A
C
18300
C
T
G
C
C
G
C
A
C
C
T
A
G
G
A
A
C
C
G
C
A
G
A
G
C
G
C
C
T
A
C
C
T
G
C
C
G
C
A
C
C
T
A
G
T
A
A
C
C
G
18350
C
A
G
A
G
C
G
C
C
T
A
C
C
T
G
C
C
G
C
A
C
C
T
A
G
G
A
A
C
C
G
C
A
G
A
G
C
G
C
C
T
A
C
C
T
G
C
C
G
C
18400
A
C
C
T
A
G
T
A
A
C
C
G
C
A
G
A
G
C
G
C
C
T
A
C
C
T
G
C
C
G
C
A
C
C
T
A
G
G
A
A
C
C
G
C
A
G
A
G
C
G
18450
C
C
T
A
C
C
T
G
C
C
G
C
A
C
C
T
A
G
T
A
A
C
C
G
C
A
G
A
G
C
G
C
C
T
A
C
C
T
G
C
C
G
C
A
C
C
T
A
G
T
18500
A
A
C
C
G
C
A
G
A
G
C
G
C
C
T
A
C
C
T
G
C
C
G
C
A
C
C
T
A
G
T
A
A
C
C
G
C
A
G
A
G
C
G
C
C
T
A
C
C
T
18550
G
C
C
G
C
A
C
C
T
A
G
T
A
A
C
C
G
C
A
G
A
G
C
G
C
C
T
A
C
C
T
G
C
C
G
C
A
C
C
T
A
G
T
A
A
C
C
G
C
A
18600
G
A
G
C
G
C
C
T
A
C
C
T
G
C
C
G
C
A
C
C
T
A
G
T
A
A
C
C
G
C
A
G
C
G
C
G
C
C
T
A
C
C
T
G
C
C
G
C
A
C
18650
C
T
A
G
T
A
A
C
C
G
C
A
G
C
G
C
G
C
C
T
A
C
C
T
G
C
C
G
C
A
C
C
T
A
G
T
A
A
C
C
G
C
A
G
C
G
C
G
C
C
18700
T
A
C
C
T
G
C
C
G
C
A
C
C
T
A
G
T
A
A
C
C
G
C
A
G
C
G
C
G
C
C
T
A
C
C
T
G
C
C
G
C
A
C
C
T
A
G
T
A
A
18750
C
C
G
C
A
G
C
G
C
G
C
C
T
A
C
C
T
G
C
C
G
C
A
C
C
T
A
G
T
A
A
C
C
G
C
A
G
C
G
C
G
C
C
T
A
C
C
T
G
C
18800
C
G
C
A
C
C
T
A
G
T
A
A
C
C
G
C
A
G
C
G
C
G
C
C
T
A
C
C
T
G
C
C
G
C
A
C
C
T
A
G
T
A
A
C
C
G
C
A
G
C
18850
G
C
G
C
C
T
A
C
C
T
G
C
C
G
C
A
C
C
T
A
G
T
A
A
C
C
G
C
A
G
C
G
C
G
C
C
T
A
C
C
T
G
C
C
G
C
A
C
C
T
18900
A
G
T
A
A
C
C
G
C
A
G
C
G
C
G
C
C
T
A
C
C
T
G
C
C
G
C
A
C
C
T
A
G
T
A
A
C
C
G
C
A
G
C
G
C
G
C
C
T
A
18950
C
C
T
G
C
C
G
C
A
C
C
T
A
G
T
A
A
C
C
G
C
A
G
C
G
C
G
C
C
T
A
C
C
T
G
C
C
G
C
A
C
C
T
A
G
T
A
A
C
T
19000
G
C
A
G
A
G
C
G
C
C
T
A
C
C
T
G
C
C
G
C
A
C
C
T
A
G
T
A
A
C
T
G
C
A
G
C
G
C
G
C
C
T
A
C
C
T
G
C
C
G
19050
C
A
C
C
T
A
G
T
A
A
C
T
G
C
A
G
C
G
C
G
C
C
T
A
C
C
T
G
C
C
G
C
A
C
C
T
A
G
T
A
A
C
T
G
C
A
G
C
G
C
19100
G
C
C
T
A
C
C
T
C
C
T
G
C
A
C
C
T
A
G
T
A
A
C
T
G
C
A
G
A
G
T
A
C
C
T
A
C
C
T
G
C
C
G
C
A
C
C
T
A
G
19150
T
A
A
C
T
G
C
A
G
A
G
T
A
C
C
T
A
C
C
T
G
C
C
G
C
A
C
C
T
A
G
T
A
A
C
T
G
T
A
G
C
G
T
A
C
C
T
A
C
C
19200
T
G
C
T
G
C
A
C
C
T
A
G
T
A
A
C
T
G
C
A
G
A
G
T
A
C
C
T
A
C
C
T
G
C
T
G
C
A
C
C
T
A
G
T
A
A
C
T
G
C
19250
A
G
T
G
C
A
C
C
T
A
C
C
T
T
T
A
A
A
G
G
C
T
T
T
T
C
A
A
G
A
A
C
A
T
A
C
A
G
A
G
C
A
T
T
T
T
C
A
A
A
19300 |
REPEAT
A
A
C
T
G
A
C
C
A
T
G
T
G
C
T
G
G
G
A
A
A
T
C
A
A
A
T
A
A
G
T
C
T
C
A
A
T
T
T
A
A
A
A
G
G
A
T
T
G
T
19350
A
A
T
C
A
T
A
A
A
A
A
T
G
T
C
C
T
C
T
G
A
G
T
A
T
A
T
T
T
C
A
A
T
T
A
T
G
T
T
C
A
A
A
A
T
T
A
A
T
T
19400
T
T
A
A
A
A
A
G
G
T
A
A
T
T
G
G
A
A
A
A
T
C
T
T
A
T
G
T
G
G
T
T
A
G
A
A
G
T
A
A
C
G
A
A
A
T
A
T
A
C
19450
T
T
T
T
A
A
A
T
A
T
C
C
C
T
T
G
G
A
T
C
A
A
A
A
A
A
A
A
T
A
A
A
T
C
A
C
A
A
T
G
G
T
A
T
T
T
A
G
A
A
19500
A
A
T
A
T
T
T
T
T
C
A
C
T
G
A
A
G
G
C
T
A
A
C
A
A
A
A
C
A
C
T
A
C
A
T
A
T
T
A
A
A
A
T
T
A
T
A
A
A
A
19550
T
G
C
A
C
T
T
T
G
C
A
A
A
G
G
A
G
T
A
C
T
T
A
A
T
A
T
A
A
C
C
T
T
A
A
A
T
A
A
A
T
A
A
A
T
A
T
T
T
C
19600
A
T
A
T
A
T
A
T
A
T
A
T
A
T
A
T
A
T
A
T
G
A
A
G
A
A
A
G
G
C
T
G
A
A
A
A
T
T
A
A
T
T
A
G
C
C
A
A
A
C
19650 |
REPEAT
A
T
T
A
T
C
T
G
A
A
G
A
A
G
A
T
A
G
C
A
A
A
T
A
A
A
C
C
T
A
G
A
G
A
A
A
A
A
A
G
A
A
G
T
A
A
A
T
A
A
19700
T
A
A
G
G
A
A
A
A
G
A
G
C
A
T
A
A
A
T
T
A
A
T
G
C
C
G
C
A
G
A
A
A
G
T
A
A
C
T
A
A
C
A
G
C
G
G
A
T
C
19750
A
A
A
A
A
A
T
C
C
A
A
A
T
A
T
T
G
G
T
T
A
T
T
C
G
A
A
A
G
G
C
T
A
A
T
A
C
A
A
T
A
G
A
C
T
A
A
T
T
A
19800
A
G
A
C
T
G
A
T
A
G
A
G
C
C
A
G
G
T
G
T
G
A
G
G
T
A
A
T
C
C
C
A
G
T
T
A
C
T
T
G
G
G
T
G
G
C
T
G
G
G
19850 |
REPEAT
G
T
G
A
G
A
G
G
A
T
C
G
T
T
T
G
A
G
G
C
C
A
G
G
A
G
T
T
T
G
A
G
A
C
C
A
G
C
C
T
A
G
G
C
C
A
C
A
C
A
19900
G
T
G
A
G
A
C
C
C
C
A
T
C
T
C
T
A
A
A
A
A
A
A
T
A
A
A
A
T
A
A
A
A
A
A
T
T
A
A
T
G
A
G
A
C
A
T
G
G
T
19950
G
G
C
A
T
G
T
G
C
C
A
G
T
A
G
T
C
C
C
A
T
G
A
A
G
G
C
T
G
A
G
A
T
G
G
G
A
G
G
A
C
T
G
C
T
T
G
A
G
C
20000
C
C
A
G
G
A
G
T
T
T
G
A
G
G
C
T
G
G
A
G
T
A
A
G
C
T
A
T
G
A
T
C
A
T
G
C
C
G
C
T
G
C
A
C
T
C
C
A
A
C
20050
C
T
G
G
G
C
A
A
C
A
G
A
G
T
G
A
G
A
C
C
C
T
A
C
T
T
C
T
G
A
G
A
A
A
A
A
A
A
A
G
A
A
A
A
A
A
A
A
G
A
20100 |
var(20070):[T:0.06]
|
REPEAT
C
T
G
A
C
A
A
A
A
A
A
G
G
A
G
A
C
A
A
G
A
T
T
G
A
A
A
T
C
C
A
T
G
A
A
T
A
A
G
G
A
G
G
A
A
T
C
A
C
T
20150
A
T
A
G
G
T
C
C
T
G
C
A
G
A
C
A
T
C
A
A
A
T
G
T
T
A
T
T
A
A
G
A
G
A
A
T
A
T
T
A
T
G
A
A
C
A
A
C
T
T
20200 |
var(20174):[G:0.17]
T
T
T
G
T
T
A
A
T
T
A
T
T
T
T
A
A
A
A
T
T
T
A
G
G
T
A
A
A
A
T
G
G
A
C
C
A
A
T
G
T
C
T
T
T
A
A
A
A
A
20250
G
T
T
C
A
A
T
T
T
A
G
C
A
A
A
G
C
T
A
A
C
T
C
A
A
A
T
A
G
A
G
A
T
A
G
A
A
A
C
T
T
A
G
A
A
T
A
T
T
C
20300
C
T
G
T
A
A
C
T
A
T
T
A
A
A
A
G
A
A
G
C
A
G
T
G
A
T
A
A
A
A
A
A
A
G
A
A
A
A
C
T
T
C
C
T
A
T
A
G
A
G
20350 |
var(20325):[G:0.01]
A
A
A
A
C
C
C
C
A
C
A
G
A
G
A
G
C
T
T
C
A
T
C
A
A
T
G
A
T
T
T
C
T
G
C
C
A
A
A
T
A
T
T
C
A
A
T
G
A
A
20400
G
A
A
A
T
T
A
T
G
T
C
A
A
T
C
T
T
A
T
A
C
A
G
T
T
T
T
C
T
C
T
A
G
A
T
A
A
T
A
G
A
G
A
A
G
A
G
A
G
A
20450 |
var(20406):[C:0.01]
A
C
T
C
T
T
C
C
A
G
A
T
T
C
A
C
T
T
T
G
T
G
T
A
A
G
C
A
T
A
A
C
C
T
T
G
A
T
T
C
C
C
A
A
A
A
C
T
G
G
20500
A
A
A
A
T
A
A
G
G
T
A
C
A
A
G
A
A
A
G
G
A
A
A
A
T
T
A
C
A
G
A
C
C
A
A
T
C
T
T
G
T
T
T
A
A
C
A
G
T
A
20550
T
A
G
A
T
G
C
A
A
A
A
G
T
T
C
T
A
A
A
T
A
A
A
A
T
A
C
T
A
T
A
A
A
C
A
A
A
C
T
C
A
A
T
T
C
A
T
C
A
A
20600
A
G
A
A
C
A
A
A
C
G
C
A
A
A
A
T
T
C
G
G
T
T
T
C
T
G
C
C
A
A
G
A
A
T
G
C
A
A
A
G
T
T
A
G
T
T
T
A
A
C
20650
T
T
T
A
T
G
A
A
A
A
T
C
T
G
T
C
A
T
T
A
T
A
A
T
T
T
A
T
T
A
C
A
T
T
G
T
C
T
T
C
T
T
A
A
A
T
G
A
G
A
20700 |
var(20682):[G:0.06]
A
A
A
A
G
A
T
A
T
A
T
C
T
T
T
T
C
A
A
T
A
G
A
T
G
C
A
G
A
T
A
A
A
T
C
T
G
T
T
G
A
T
A
A
A
A
T
G
T
A
20750
A
T
G
T
T
T
A
T
T
C
A
T
G
A
T
T
A
A
A
A
A
T
G
C
T
A
G
C
A
A
G
T
C
A
G
A
A
A
A
G
A
A
A
T
T
C
C
T
T
T
20800
T
C
T
G
A
T
A
A
T
A
A
G
G
T
A
T
C
T
T
G
A
A
A
C
G
A
A
C
A
G
A
A
G
T
T
T
T
G
T
A
C
T
T
A
T
T
T
T
A
A
20850 |
var(20824):[T:0.07]
C
A
A
A
A
T
G
T
T
A
A
C
A
G
C
C
T
T
T
T
T
T
T
T
T
T
T
T
T
T
T
T
G
A
G
G
C
A
A
G
G
T
C
T
T
A
C
T
C
T
20900 |
REPEAT
G
T
T
G
C
C
T
A
G
G
C
T
G
G
A
G
T
G
C
A
G
T
G
G
C
G
T
G
A
T
C
A
C
G
G
C
T
T
A
C
T
G
T
A
T
C
C
T
T
G
20950
A
C
C
T
C
C
C
A
G
G
C
C
G
A
A
G
C
A
A
T
C
C
T
C
T
C
A
C
C
T
C
A
G
C
C
C
C
C
T
G
A
G
G
G
A
C
C
A
C
A
21000 |
var(20989):[:0.03]
G
G
C
A
T
G
C
A
C
C
A
C
C
A
T
G
C
C
T
G
G
C
T
A
A
T
T
T
G
T
A
T
T
T
T
T
T
G
T
A
G
A
G
A
C
A
G
G
A
T
21050
T
T
T
G
C
C
A
T
G
T
T
G
C
C
C
A
G
G
C
T
G
G
T
C
T
C
A
A
A
C
T
C
A
T
G
A
G
C
T
C
A
A
G
C
C
A
T
C
T
G
21100 |
var(21057):[G:0.03]
C
C
C
T
C
T
T
C
A
G
C
T
T
C
C
C
A
A
A
G
T
G
C
T
G
G
A
A
T
T
A
C
A
A
G
G
C
A
T
G
A
G
C
C
A
C
T
G
T
G
21150
T
C
C
A
G
C
C
C
A
C
C
T
T
T
C
T
C
T
G
A
A
A
T
A
A
T
A
T
G
C
A
A
G
A
C
C
A
A
G
C
T
A
C
T
T
A
C
C
A
C
21200 |
REPEAT
|
var(21199):[G:0.01]
C
C
C
T
A
T
T
T
C
T
G
G
T
C
A
G
C
C
T
G
G
T
A
C
T
G
G
A
G
G
C
C
C
T
A
G
C
T
A
T
T
T
T
A
G
T
A
G
A
G
21250
C
A
A
G
A
A
A
A
A
G
A
A
A
G
A
A
G
A
G
A
T
A
T
A
G
G
A
T
T
G
G
A
A
A
A
G
A
A
G
A
A
A
C
A
A
A
A
C
T
G
21300
T
T
C
A
T
A
G
G
T
T
A
T
A
G
G
A
T
G
T
G
T
A
C
A
T
A
G
A
A
A
A
A
C
T
C
A
A
A
A
G
T
A
T
C
TTTTAA
21350
ATTAATAATA GTTTAGTT
A
T
A
A
A
A
A
T
C
A
A
T
A
T
A
T
A
A
A
A
A
T
A
A
A
T
C
T
T
A
C
A
21400 |
REPEAT
|
var(21370):[A:0.01]
A
A
A
G
G
T
A
T
G
T
A
G
T
A
A
C
T
C
T
A
A
A
A
G
T
A
T
A
A
C
C
T
T
A
A
T
T
G
A
G
A
G
A
C
A
T
A
A
G
A
21450 |
var(21436):[C:0.01]
C
C
A
A
A
G
T
A
A
G
T
G
A
A
G
A
A
A
T
A
T
A
C
C
A
T
T
T
A
C
T
T
T
G
T
G
A
T
T
C
G
G
A
A
G
T
C
A
C
C
21500
A
T
A
G
T
A
C
G
A
A
G
A
T
G
T
C
A
G
C
T
C
T
T
C
T
C
A
A
A
T
T
G
A
T
C
T
A
T
A
G
A
A
T
C
A
A
T
G
C
A
21550 |
var(21525):[C:0.20]
A
T
C
T
C
A
A
C
C
A
A
T
A
T
C
T
C
A
A
G
T
T
T
T
T
T
T
T
T
T
T
T
T
T
T
T
T
T
T
T
T
T
T
T
T
T
T
G
A
G
21600 |
REPEAT
|
var(21579):[G:0.03]
|
var(21584):[G:0.03]
|
var(21587):[C:0.03]
|
NOT SCANNED
A
C
A
G
A
G
T
C
T
C
G
C
T
C
T
G
T
C
T
C
C
C
A
G
G
C
T
G
G
A
G
T
G
C
A
G
T
G
G
C
A
T
G
A
T
C
T
C
G
G
21650
C
T
C
A
C
T
G
C
A
A
G
C
T
C
T
G
C
C
T
C
C
T
G
G
G
T
T
C
A
T
A
C
A
A
T
T
C
T
C
C
T
G
C
C
T
C
A
G
T
C
21700
T
C
C
T
G
A
G
T
A
G
C
T
G
G
G
A
C
T
A
C
A
G
G
C
G
C
C
C
A
C
C
A
C
C
A
C
A
C
C
C
A
G
C
G
A
A
T
T
T
T
21750
T
T
T
T
T
T
T
T
T
T
A
A
T
A
G
A
G
A
C
G
G
T
G
T
T
T
C
A
C
C
G
T
G
T
C
A
G
C
T
A
A
G
A
T
G
G
T
C
T
C
21800
G
A
T
C
T
C
C
C
G
A
C
C
T
C
G
T
G
A
T
C
T
G
C
C
C
G
T
C
T
C
A
G
C
C
T
C
C
C
A
G
A
G
T
G
C
T
G
G
G
A
21850 |
var(21827):[C:0.18]
T
T
A
C
A
G
G
T
G
T
G
A
G
G
C
A
C
C
G
T
G
C
C
C
A
G
C
C
AA GTA
T
T
T
T
G
T
T
T
T
G
T
T
T
T
G
T
T
21900 |
REPEAT
T
T
G
T
T
T
T
G
T
T
T
T
T
G
A
G
A
C
A
G
A
G
T
C
T
T
G
C
T
C
T
G
T
T
G
C
C
C
A
C
G
C
T
G
G
A
G
T
T
C
21950 |
var(21903):[:0.97]
|
var(21927):[T:0.02]
A
G
A
G
G
C
G
C
A
A
T
C
T
C
G
G
C
T
C
A
C
T
G
A
A
A
C
C
T
C
T
G
C
C
T
C
C
C
G
C
G
T
T
C
A
A
G
C
A
A
22000 |
var(21988):[A:0.07]
T
T
C
T
C
C
T
A
C
C
T
C
A
G
C
C
T
C
C
C
G
A
G
T
A
G
C
T
G
G
G
A
T
T
A
A
A
A
G
C
G
T
G
C
G
C
C
A
C
C
22050 |
var(22021):[A:0.03]
A
T
G
C
C
C
G
G
C
T
A
A
T
T
T
T
T
G
T
A
T
T
T
T
T
A
G
T
A
G
A
C
A
T
G
G
G
G
T
T
T
C
A
C
T
A
T
G
T
T
22100
G
G
C
C
A
G
G
C
T
G
G
T
C
T
C
A
A
A
C
T
C
C
T
G
A
C
C
T
C
A
A
A
T
G
G
T
C
C
G
C
C
T
G
C
C
T
T
G
G
C
22150
C
T
C
C
C
A
A
A
G
G
G
C
T
G
G
G
A
T
T
A
C
A
G
G
T
G
T
G
A
G
C
C
A
C
C
A
C
G
C
C
C
A
G
C
C
TATAT
22200 |
var(22191):[T:0.01]
|
var(22192):[G:0.20]
CTCAACCTTT TAGTTTTGTG TGTGTGTGGC AAGTGGGTGT GAGGA
G
T
G
G
A
22250 |
REPEAT
A
C
T
T
G
A
C
A
A
A
C
C
T
A
C
T
C
T
G
A
A
A
T
C
C
A
T
A
T
G
A
A
A
A
G
G
T
A
A
A
G
A
A
G
A
G
A
A
T
A
22300
A
G
A
T
C
A
G
C
C
A
G
G
A
T
G
C
C
C
T
T
G
A
A
G
A
A
G
G
A
C
A
A
G
A
C
T
A
G
T
A
G
T
G
A
A
G
G
G
T
T
22350
T
G
C
C
T
T
A
T
C
A
G
A
T
T
C
T
T
G
T
C
A
A
G
A
A
T
T
A
T
T
A
T
A
A
A
G
C
T
A
T
A
T
T
A
A
A
A
A
G
A
22400
C
A
G
T
G
G
T
A
T
T
G
G
T
G
T
A
G
G
T
T
G
G
A
C
A
G
A
T
A
C
T
G
T
T
G
G
A
A
T
G
G
A
G
T
T
G
A
A
A
A
22450
C
C
C
A
T
A
G
A
T
C
T
A
C
A
C
A
T
A
C
C
T
A
G
A
A
A
C
T
T
G
A
T
T
T
T
C
A
C
A
G
A
G
A
T
G
G
C
A
C
T
22500 |
REPEAT
|
var(22498):[C:0.03]
G
T
A
G
A
G
C
A
G
T
G
G
G
G
A
A
G
T
G
A
C
A
G
T
C
T
T
T
T
C
A
G
T
A
A
A
T
G
G
T
G
C
T
G
A
G
A
C
A
A
22550
C
T
G
G
G
T
A
T
C
C
A
C
A
T
G
G
T
A
C
A
G
A
A
A
T
G
A
A
A
T
T
G
G
G
C
T
T
C
T
A
C
C
T
T
A
C
A
C
C
A
22600 |
REPEAT
T
A
C
C
A
A
A
A
A
A
T
C
A
G
C
T
C
C
A
G
G
T
T
G
A
T
T
A
C
T
G
A
C
A
G
A
A
A
T
G
T
G
A
A
A
G
A
T
A
A
22650
A
A
T
T
A
T
A
A
A
G
C
T
A
T
T
G
G
A
A
A
A
T
A
T
A
G
G
A
G
A
A
T
T
T
G
T
C
C
A
T
A
T
C
C
T
C
A
G
G
G
22700 |
var(22652):[G:0.01]
T
A
G
G
G
G
A
T
C
C
T
C
A
A
C
A
G
T
A
T
A
C
A
A
A
A
G
C
A
T
T
A
G
C
T
G
T
A
G
T
G
G
T
A
A
G
A
A
C
T
22750
G
A
T
A
A
A
T
T
T
T
A
A
A
A
T
T
T
A
T
A
A
A
A
T
T
TTAAA TGAATGTTTA AAACGAATTT
22800
ATAAACGAAT TCATTGTAAA ATTCTATAAA TTATTTATAA ATAAATTTAT
22850
ACATTTATAA ATTTAGAAGA TTTTTAAATG AATGTATACA TTCAT
T
T
T
A
A
22900 |
REPEAT
A
A
C
T
T
T
T
A
T
T
C
A
T
C
A
A
A
A
T
A
A
A
C
C
A
T
T
A
A
G
A
G
A
A
T
G
G
A
G
G
C
A
G
G
G
C
A
T
G
G
22950 |
REPEAT
T
G
G
C
T
C
A
T
G
C
C
T
G
T
A
A
T
C
C
C
A
G
C
A
C
T
T
T
G
G
G
A
G
G
C
T
G
A
G
G
T
G
G
G
A
G
G
A
T
C
23000
G
C
T
T
G
A
G
G
C
C
A
G
G
A
G
T
T
T
G
A
G
A
C
T
A
G
C
C
T
G
G
G
C
A
A
C
A
T
A
G
T
G
A
G
A
C
C
T
C
C
23050
T
C
T
T
T
A
C
A
A
A
T
A
A
T
A
A
T
T
A
A
G
A
A
A
T
T
A
G
C
T
G
G
G
C
G
T
G
G
T
G
G
T
G
C
C
C
A
C
T
T
23100 |
var(23085):[A:0.01]
T
C
G
G
T
C
C
C
A
G
C
T
A
C
T
C
A
G
G
A
G
G
C
T
G
A
G
A
T
G
A
G
A
T
G
A
C
T
G
C
T
T
G
G
G
C
C
C
A
G
23150 |
var(23149):[G:0.27]
G
A
G
G
C
T
G
C
G
C
C
A
T
T
G
C
G
C
T
C
C
A
G
C
C
T
G
G
G
T
T
A
C
T
G
A
A
T
G
A
G
A
C
C
C
C
A
T
C
T
23200 |
var(23167):[A:0.03]
|
var(23184):[:0.15]
C
C
A
A
T
A
A
A
T
A
A
A
T
A
A
A
T
A
A
A
T
A
A
A
C
C
A
G
T
C
A
C
A
G
A
A
T
G
G
G
A
G
A
A
G
T
G
C
A
A
23250 |
REPEAT
C
A
C
A
C
A
C
A
T
A
A
C
T
G
A
C
A
A
A
G
G
A
C
T
T
G
A
A
T
A
C
A
T
A
A
A
A
T
C
T
A
G
A
G
A
A
A
T
T
G
23300
T
A
T
A
A
A
T
C
G
G
A
A
A
G
G
A
A
A
A
G
A
T
A
T
G
C
A
A
C
C
C
A
G
T
T
A
A
A
A
C
A
G
G
G
A
T
G
A
A
A
23350
T
A
G
C
T
G
A
A
T
G
G
G
C
A
C
T
T
C
A
C
C
A
A
A
G
A
G
A
A
T
A
A
A
T
A
C
A
C
C
A
A
A
A
A
A
G
T
G
C
A
23400
C
A
A
C
T
T
T
A
C
T
G
G
T
A
A
T
T
A
G
A
G
A
A
A
T
G
C
A
A
A
T
T
A
A
A
A
C
C
A
C
A
A
T
A
A
G
A
T
A
A
23450
T
A
T
T
A
T
G
T
G
T
C
T
A
A
A
C
A
T
T
G
G
C
A
A
A
T
A
T
GG CAAGGCTTTT CTAAACAACA
23500
TGAAATAAAT CCAAATAAAC AGTGAAATGT GTTTATGGAT GGAAAGACTT
23550
GACATACTAA AGCTGTCTAT TCTCCCCAAC ATGATTTATA AAAGGAGTGC
23600
AATCCTAATT AAAAGCACAA CCAAATTCTT TATGGAATTC AACAAGCTGA
23650
CTCTTAAGTT ACACAAAATG TACAAAGATA GCTAAGAAAA TTCTGAAGGA
23700
GGAGATCAGA ACAGTGTAGA CTA
C
AGCAAG GATAATCAAA TAGATTAATA
23750 |
var(23724):[T:0.03]
GAAAAGGTGA GTCT
T
T
G
C
A
G
G
T
T
G
G
G
T
T
T
T
C
C
A
G
A
A
G
C
A
G
C
C
A
C
T
G
A
G
T
T
23800 |
REPEAT
G
G
A
G
A
T
T
G
G
G
G
T
G
C
A
A
G
GAA GGAGTGGGAA GCAGGAATGA GCAGAGGAAG
23850
AAGTCAGAAG GCAACGAAGC CTGACAGCTC TGGCAGCCGG GAGCACTGAG
23900
CAAATGCCCC TCAGGCTTGT CCCACGTCAG ACTGAAATGG CCAAGGCTTT
23950
ATCCCCTCGC CTTTCTCAGT CACTGGCTCA GAAGGGGAGT ACCTGGGGCA
24000
AAGGAGTTCA CAGCTGCAGG CTGTTTGTTC ACTCAGCTCC TTGCAACAGG
24050
GCAGCAAATC CCTCCTTGAG GGGGAATCTG AGAGGCCCAT CACTGTGTCT
24100
ACCACAAAGT CCAAAATCAA TCCATGTATG TTTCTTAAGC CACACACAAA
24150
ATTCGCAAGG TATAAAGAAA AAGATTATTG TATATGACTT CATGAAAATG
24200
GAAAGGTAGT CAAAAAGGAG AAATTGTGTT TAGCAAAGGA TTAA
T
A
T
C
C
A
24250 |
REPEAT
G
G
A
T
A
T
T
T
A
A
T
A
G
A
G
T
G
C
C
T
A
C
A
A
A
T
A
A
A
A
A
A
C
A
A
A
A
A
T
A
G
G
C
C
G
G
G
T
G
C
24300 |
REPEAT
G
G
T
G
G
C
T
G
A
C
G
C
C
T
G
T
A
A
T
C
C
C
A
G
C
A
C
T
T
T
G
G
G
A
G
G
C
C
G
A
G
G
C
T
G
G
T
G
G
A
24350
T
C
A
C
G
A
G
A
T
C
A
G
G
A
G
A
T
C
G
A
G
A
C
C
A
T
C
C
T
G
G
C
T
A
A
C
A
T
G
G
T
G
A
A
A
C
C
C
C
A
24400
T
C
T
C
T
A
C
T
A
A
A
A
A
T
A
C
A
A
A
A
A
A
T
T
A
G
C
C
A
G
G
C
G
T
G
G
T
G
G
C
A
G
G
C
A
C
C
T
G
C
24450
A
G
T
C
C
C
A
G
C
T
A
C
T
T
G
G
G
A
G
G
C
T
G
A
G
G
C
A
G
G
A
G
A
A
T
G
G
T
G
T
G
A
A
C
C
C
A
G
G
A
24500
G
G
C
G
G
A
G
C
T
T
G
C
A
G
T
G
A
G
C
C
G
A
G
A
T
G
G
A
G
C
C
A
C
T
G
C
A
C
T
C
C
A
G
C
C
T
G
G
G
T
24550
G
A
C
A
A
A
G
T
G
A
G
A
C
T
C
C
G
T
C
T
C
A
A
A
A
A
A
A
C
A
A
A
C
A
A
A
A
A
A
A
C
C
A
A
A
A
T
A
A
A
24600
A
G
A
A
A
A
A
T
A
A
T
A
G
A
C
A
A
A
G
A
A
C
A
T
A
G
A
C
A
A
T
T
C
A
A
A
A
A
A
G
A
A
ACTGAACA
24650 |
REPEAT
ACATACTTCA GAAAAGATAT TTGGC
C
T
C
G
C
C
A
A
C
A
G
A
G
A
A
A
G
G
C
A
A
A
A
T
G
24700 |
REPEAT
|
var(24678):[T:0.20]
A
A
C
C
C
G
T
T
A
C
A
A
T
T
T
T
T
C
A
T
C
C
A
T
T
A
G
A
T
T
G
A
A
A
T
T
T
T
T
G
A
A
A
G
A
T
T
A
G
T
24750
G
A
T
A
C
A
G
T
G
T
G
T
T
G
G
T
G
A
A
A
A
T
G
C
A
G
A
A
T
A
A
C
A
A
G
C
A
G
T
C
T
T
C
T
G
C
A
G
T
G
24800
T
T
G
G
T
A
A
G
A
G
T
G
GCGAAGTT TATTAGAAGG TGAGGCACCC AACAAACTCC
24850
ACAAGCCCAT AAGTTTGGCT GCAGTTCTAC TCTCAGTAAT CTATACTGCT
24900
CACGTGCACT CAAAGATGTA GTTTCC
A
T
T
C
T
T
T
G
C
A
C
C
T
T
A
G
T
T
T
A
T
A
A
G
24950 |
REPEAT
A
G
T
G
A
A
A
A
A
T
T
A
G
A
A
A
C
A
A
C
T
C
A
A
A
T
G
T
C
C
A
T
A
A
G
T
A
A
C
T
G
C
C
C
T
A
A
A
T
T
25000
A
T
G
A
T
T
C
A
T
C
T
A
A
A
C
T
A
C
A
G
A
A
T
A
C
T
A
A
T
A
G
C
C
A
T
T
T
A
A
A
A
G
A
A
A
G
A
G
G
T
25050
G
G
A
A
A
C
T
A
A
C
A
T
G
T
A
A
T
G
A
T
A
T
A
G
A
A
A
G
A
T
C
T
T
C
A
A
G
A
T
T
A
G
C
T
G
T
T
A
G
T
25100
G
A
A
A
A
A
A
A
T
A
A
G
T
C
A
C
A
A
A
A
C
A
A
T
A
C
T
T
A
C
A
G
T
G
T
G
G
T
C
C
T
T
T
T
A
A
T
G
T
T
25150
A
A
A
G
A
TATAT ATATTTT
G
G
C
C
T
G
G
T
G
C
A
G
T
G
G
C
T
C
A
T
G
C
C
T
G
T
A
A
T
T
C
C
A
25200 |
REPEAT
G
C
A
C
T
A
T
G
G
G
A
G
G
C
G
G
A
G
T
T
G
T
A
C
A
G
A
T
C
A
C
T
T
G
A
G
G
T
G
A
G
G
A
G
T
T
G
G
A
G
25250 |
var(25237):[A:0.01]
A
C
C
A
G
C
T
G
G
C
C
A
A
C
A
T
G
G
T
A
A
A
A
C
C
C
C
G
T
C
T
C
T
A
C
T
A
A
T
A
A
T
A
C
A
A
A
A
A
A
25300
A
A
C
T
G
G
C
C
A
G
G
T
A
T
G
G
T
G
G
T
G
C
A
T
G
T
C
C
A
T
A
A
T
C
C
C
A
G
C
T
A
C
T
C
A
G
G
A
G
G
25350
C
T
G
A
G
G
C
A
T
G
A
G
A
A
T
T
G
C
T
T
G
A
A
C
C
C
G
G
G
A
G
G
T
G
G
A
G
G
T
T
G
C
A
G
T
G
A
G
C
C
25400
A
A
G
A
T
T
G
T
G
C
C
A
C
T
A
C
A
C
T
C
C
A
T
C
C
T
G
G
G
C
A
A
C
A
G
A
G
T
G
A
A
A
C
T
G
T
G
T
C
T
25450
C
A
A
A
TATATA TATATTTCTG GAATGTGTGT GCAAATTCCT AGAGAGAGAA
25500
TAAGAGTGAT ATGCATCACA CTCTGGATAA GGCTTACCTC TAGAGAATGG
25550
AAGAGTAGGT GCTGAAGGAA TGTTTGGATG TTATTCTATG TGATTCTGCA
25600
TTGTTTGAAT CTTTGGGGG
T
T
T
T
T
T
T
G
G
T
T
T
T
C
T
T
T
T
T
G
A
G
A
C
G
G
T
C
T
T
A
25650 |
REPEAT
C
T
C
T
G
T
C
A
C
C
C
A
G
G
C
T
G
G
A
G
T
G
C
A
G
T
G
A
C
A
C
A
A
T
C
T
G
G
G
C
T
C
A
C
T
A
C
A
A
C
25700
C
T
C
C
A
C
C
T
C
C
C
G
G
G
T
T
C
A
A
G
T
G
A
T
T
C
T
C
G
T
G
C
C
T
C
A
G
C
C
T
C
C
C
G
A
G
T
A
G
C
25750
T
G
G
G
A
T
T
A
C
A
G
G
C
G
T
G
T
A
C
C
A
C
C
A
C
A
C
C
C
A
G
C
T
A
A
T
T
T
T
T
T
T
G
T
A
C
T
T
T
T
25800 |
var(25753):[:0.17]
A
G
T
A
G
A
G
A
T
G
G
G
G
T
T
T
C
A
C
C
A
T
G
T
T
G
G
C
C
A
G
G
C
T
G
G
T
C
T
T
G
A
A
C
T
C
C
T
G
A
25850
C
C
T
C
A
A
G
C
G
A
T
C
T
G
C
T
C
G
C
C
T
C
G
G
C
C
T
C
C
T
A
G
A
G
T
G
C
T
G
G
G
A
T
T
A
C
A
G
G
C
25900
G
T
G
A
G
C
C
A
C
C
A
T
G
T
C
T
G
G
C
C
TGTTTGAATC TTTCAAAAGG ACTTTGTACT
25950
TAACATATTT GTGTAATAAA AATAACTATA AAAAGAAAAT CAATTTGATA
26000
AAATTAAAAT AACAAAAATA CTTTTCATAT TA
G
G
C
T
A
A
G
C
A
G
G
G
T
G
G
C
T
C
26050 |
REPEAT
G
T
G
C
C
T
G
T
A
A
T
C
T
C
A
G
C
A
C
T
T
T
G
G
G
A
G
G
C
T
G
A
G
G
T
G
G
G
T
G
G
A
T
T
T
C
T
T
G
A
26100
G
G
C
C
A
G
T
T
C
A
A
A
A
C
C
A
G
C
A
A
C
A
T
G
G
C
A
A
A
A
A
C
C
G
A
T
C
T
C
T
A
C
A
A
A
A
A
A
C
A
26150
C
A
A
A
A
A
T
T
A
G
C
C
A
A
G
C
G
T
G
G
T
G
G
C
G
C
A
T
G
C
C
T
G
T
T
G
T
C
C
C
A
G
C
T
A
C
A
C
A
G
26200
G
A
G
G
C
T
G
A
G
G
T
G
G
C
A
G
G
C
T
C
T
C
T
T
G
A
G
C
C
T
G
G
A
G
G
T
T
G
A
G
C
C
T
G
C
A
C
T
C
T
26250
A
G
C
C
T
G
G
A
G
G
A
C
A
C
A
G
T
G
A
G
A
C
T
C
T
G
T
C
T
C
A
A
G
A
A
A
A
A
A
A
A
C
A
A
C
A
A
A
A
A
26300
A
CCCTTTTCA TGTTAATTAA AAACAATAAA CATACA
G
C
T
G
G
G
T
G
A
G
G
T
G
G
26350 |
REPEAT
|
var(26349):[A:0.01]
C
T
C
A
T
G
C
C
T
G
T
A
A
T
C
C
C
A
G
C
T
C
T
T
T
G
G
G
A
G
G
A
C
A
A
G
C
T
G
G
G
A
G
G
A
T
T
G
C
T
26400
T
G
A
G
C
C
C
A
G
G
A
G
T
T
G
G
A
G
G
T
T
T
C
A
G
T
G
A
G
C
T
A
T
G
A
C
C
A
T
G
C
C
A
C
T
G
C
A
C
T
26450
C
C
T
G
C
C
T
G
G
G
C
G
A
C
A
G
A
G
G
C
A
G
A
T
T
T
G
A
T
C
T
C
T
A
A
A
A
A
T
A
A
A
C
A
T
G
C
A
A
A
26500 |
var(26452):[T:0.07]
|
var(26470):[G:0.16]
G
A
G
A
C
A
A
A
A
A
C
A
A
TATATAG AATGCTACAA AGTGTGAACA TAATTAATAC
26550
CCTCTGTCAT TCTCCCCTAG ATCATGCATG TATTCATTTA GCTAGTATTT
26600
TTGACCACTT ATTTATATAG CAGACAATC
T
GTTAACAGCA AAATACAAAT
26650 |
var(26630):[:0.84]
AAAACTAGGA
A
A
A
A
A
A
A
A
A
A
C
T
T
G
A
A
G
G
A
A
A
A
A
T
A
C
C
A
A
A
G
T
G
T
T
A
A
C
A
T
26700 |
REPEAT
T
T
T
A
T
C
T
T
T
G
G
G
T
G
T
A
G
G
G
C
A
A
A
A
C
T
A
T
G
G
A
T
A
G
G
T
T
T
T
A
AGAATATATA
26750
ATTTTCTATG TTTTCTATAA TGAGGATTAT TGCTCCTATA AGGAAAAAG
T
26800 |
REPEAT
T
T
T
T
T
A
C
T
G
T
G
G
C
A
A
A
A
T
A
T
A
C
T
T
A
A
C
A
T
A
A
A
A
T
T
C
T
C
T
A
T
T
T
T
A
A
C
C
A
T
26850
T
T
T
T
A
A
G
T
G
A
A
C
A
A
T
C
C
A
G
T
G
G
C
A
T
T
A
A
G
T
A
C
A
T
T
C
A
T
A
A
T
G
T
T
G
T
G
C
G
G
26900
C
C
A
T
T
A
C
C
A
C
T
A
T
C
T
A
T
A
T
C
T
A
G
A
A
C
T
T
T
T
T
T
A
T
C
A
T
C
C
C
A
A
A
C
T
G
A
A
A
C
26950
T
C
T
G
T
A
C
C
T
G
C
T
A
A
A
C
G
G
T
A
A
C
T
C
C
C
C
A
T
T
C
C
T
C
C
C
T
C
T
C
C
C
A
G
C
C
C
C
T
G
27000
G
T
A
G
C
T
T
C
T
A
T
T
C
T
G
T
T
T
T
C
T
G
T
C
T
C
T
G
A
A
T
T
C
T
A
G
G
T
A
G
C
T
C
C
T
A
G
C
A
A
27050
A
A
G
G
A
T
C
A
C
A
C
A
A
T
G
T
A
T
T
T
C
C
T
T
T
G
G
A
G
T
C
T
G
G
C
A
T
A
T
T
T
C
A
C
T
T
A
G
C
A
27100 |
var(27056):[C:0.06]
T
A
A
T
G
T
T
T
T
C
A
A
G
G
T
T
C
A
T
C
T
G
T
T
T
C
A
T
A
G
C
A
T
G
T
A
T
C
A
G
A
A
T
T
T
C
A
T
T
C
27150
C
C
T
T
T
T
A
T
G
G
C
T
G
A
A
T
A
A
C
A
T
T
C
C
A
T
C
A
T
A
T
G
G
A
T
A
T
A
C
A
G
G
T
T
G
A
A
C
A
T
27200 |
REPEAT
C
C
C
T
A
A
A
C
C
C
A
A
A
A
T
C
C
A
A
A
A
T
T
C
A
A
A
A
T
C
C
T
C
C
A
A
A
A
T
C
T
G
A
A
A
C
G
T
T
T
27250 |
var(27215):[C:0.07]
T
G
A
G
T
G
C
C
A
G
C
A
T
G
A
T
G
C
C
A
C
A
A
G
T
G
G
A
A
A
A
T
A
C
C
A
C
A
C
C
T
G
A
C
A
C
C
T
C
T
27300
G
C
T
T
T
C
T
G
A
T
A
G
T
T
C
A
G
T
A
T
C
C
T
C
A
A
A
C
T
T
T
G
T
T
T
C
A
T
G
C
A
C
A
A
A
A
T
T
A
T
27350
T
A
A
A
A
T
A
T
G
G
T
A
T
A
A
A
G
T
G
A
C
C
T
T
C
A
G
G
C
T
A
T
G
T
G
T
A
T
A
A
G
G
T
G
C
A
T
A
T
G
27400
A
A
A
C
A
C
A
A
A
T
A
A
A
C
T
T
C
A
T
G
T
T
T
A
G
A
C
T
T
A
G
G
T
C
C
T
C
T
C
C
C
C
A
C
G
A
T
C
T
G
27450
T
C
A
T
T
C
T
G
T
A
C
A
T
G
C
A
A
A
T
A
T
T
C
C
C
A
A
A
T
T
G
G
A
A
A
C
A
A
T
C
C
A
A
A
A
T
C
C
A
A
27500
A
A
C
A
C
T
T
C
T
A
A
T
C
C
C
A
A
G
C
A
T
T
T
T
G
G
A
T
A
A
G
G
G
A
T
A
C
T
A
C
A
C
C
T
G
C
A
C
C
A
27550 |
REPEAT
T
A
T
T
T
T
G
A
G
T
T
C
C
T
G
C
C
T
T
C
A
G
T
T
C
T
T
T
G
G
G
G
T
A
T
A
T
A
T
A
T
C
C
G
G
G
T
G
T
G
27600 |
REPEAT
G
A
A
T
T
G
C
T
A
G
A
T
C
A
T
A
T
G
G
T
A
A
T
T
C
T
A
T
G
T
A
T
A
A
C
T
T
T
T
T
G
T
T
T
T
T
C
T
G
A
27650 |
REPEAT
G
A
C
A
G
A
G
T
C
T
C
C
C
T
C
T
G
T
T
G
C
C
C
A
G
G
C
T
G
G
A
A
T
G
C
A
G
T
G
G
C
A
C
C
A
T
C
T
C
G
27700 |
var(27656):[:0.07]
G
C
T
C
A
C
T
G
C
A
A
C
C
T
C
C
G
C
C
T
C
C
C
G
G
G
T
T
C
A
A
G
C
G
A
T
T
C
T
C
C
T
G
C
C
T
C
A
C
C
27750
T
T
C
C
C
G
A
G
T
A
G
C
T
G
G
G
A
T
T
A
C
A
G
G
C
A
T
A
C
A
C
C
A
C
C
A
C
G
C
C
C
G
G
C
T
A
G
T
T
T
27800 |
var(27796):[G:0.06]
T
T
T
G
T
A
T
T
T
T
T
A
G
T
A
G
A
G
A
T
G
G
G
G
T
G
G
T
T
T
C
A
C
C
A
T
G
T
T
G
T
C
C
A
G
G
C
T
G
G
27850
T
C
T
C
A
A
A
C
T
C
C
T
A
A
C
C
T
C
A
G
G
T
G
A
T
C
T
G
A
G
G
T
C
C
C
A
A
A
G
T
G
C
T
G
G
G
A
T
T
A
27900
C
A
G
G
C
G
T
G
A
G
C
T
C
C
C
A
T
G
C
C
C
G
G
C
C
A
T
G
T
T
T
A
A
C
T
T
T
T
A
A
G
T
A
C
T
G
T
T
A
A
27950 |
REPEAT
A
A
T
T
G
T
T
T
T
A
C
A
T
G
G
T
A
G
C
T
A
C
A
C
C
A
T
T
T
T
A
T
A
T
T
C
C
C
C
A
C
C
A
G
C
A
A
T
G
C
28000
A
C
A
A
G
G
A
T
T
C
T
A
A
T
T
T
C
T
C
C
A
C
C
A
T
C
T
T
A
C
C
A
A
C
A
C
T
T
T
T
T
A
T
T
T
A
C
C
A
T
28050
T
T
T
T
A
T
A
T
T
A
T
A
G
T
C
A
C
T
C
T
A
A
G
G
A
G
T
G
T
G
A
A
A
G
T
G
T
A
C
C
T
C
A
T
G
G
T
G
G
T
28100
T
T
T
G
A
C
T
T
G
C
A
T
T
T
C
C
C
T
A
T
G
A
C
T
C
A
T
G
A
T
G
T
T
G
A
G
C
A
T
C
T
T
C
A
T
G
G
C
T
T
28150
A
T
T
G
G
C
C
A
T
T
T
G
T
A
T
A
T
C
T
T
C
T
A
T
G
G
A
G
A
A
A
C
T
G
C
T
A
T
T
C
A
A
G
T
T
C
T
T
T
G
28200
C
C
C
A
T
T
T
T
T
G
A
A
T
T
G
G
G
T
T
G
T
T
T
G
T
T
T
T
T
T
G
T
T
G
T
T
G
A
G
T
T
G
T
A
G
G
A
T
T
T
28250
T
T
T
T
T
T
T
T
T
A
T
G
T
T
C
T
G
G
A
T
T
T
C
A
T
C
C
G
T
T
T
T
C
A
G
A
T
A
T
A
T
A
T
T
G
T
T
T
G
C
28300
A
A
C
T
T
T
T
T
C
C
C
C
A
T
T
A
T
T
T
T
A
T
T
T
T
A
T
T
T
A
T
T
T
A
T
T
T
T
T
T
T
T
T
T
G
G
A
G
A
C
28350 |
REPEAT
A
G
A
A
T
C
T
T
G
C
T
C
T
G
T
C
G
C
C
A
C
C
C
A
G
A
C
T
G
G
A
G
T
G
C
A
G
T
G
G
C
A
G
A
A
T
G
T
T
G
28400
G
T
T
C
A
C
T
G
C
A
A
C
C
T
C
T
G
C
C
T
C
C
C
A
G
G
T
T
C
A
A
G
A
G
A
T
A
A
C
T
C
C
T
G
C
C
T
C
A
G
28450
C
C
T
C
C
C
G
A
G
T
A
G
C
T
A
G
G
A
C
T
A
C
A
G
G
C
A
C
A
C
A
C
C
A
T
C
A
T
G
C
C
T
G
G
T
T
A
G
T
T
28500
T
T
T
G
T
A
T
T
T
T
T
A
G
T
A
G
A
G
A
C
A
A
G
G
T
T
T
C
A
C
C
A
T
G
T
T
G
G
C
C
T
G
G
C
A
G
G
T
C
T
28550
C
G
A
A
C
T
C
C
T
G
A
C
C
T
C
A
T
G
G
G
A
T
C
C
A
C
C
T
G
C
C
T
T
G
G
C
C
T
C
C
C
A
A
A
G
T
A
T
T
T
28600 |
REPEAT
T
T
T
C
C
T
T
A
T
T
C
T
G
T
A
G
G
T
T
A
T
C
T
T
T
T
T
A
C
T
C
T
T
T
T
C
A
T
A
G
T
A
T
C
C
T
T
T
G
A
28650
T
G
C
A
C
A
G
A
A
G
C
T
T
T
T
A
A
T
T
C
T
G
A
T
G
T
A
T
T
A
T
T
T
T
T
A
C
T
C
T
T
T
A
C
T
T
T
T
G
T
28700
T
T
G
T
G
C
T
T
T
T
G
T
G
T
C
A
T
A
A
C
C
A
A
G
A
A
A
T
C
G
C
T
G
C
C
A
A
G
T
C
C
A
A
T
G
T
C
A
T
G
28750
A
A
G
C
T
T
T
T
T
C
C
C
T
G
T
G
T
T
T
T
C
T
T
C
T
A
A
G
A
A
T
T
T
T
T
G
T
G
G
C
A
C
T
A
G
C
C
C
T
T
28800
A
A
A
T
T
A
A
G
T
C
T
T
T
G
A
T
C
C
A
T
T
G
T
G
A
G
T
T
A
A
T
T
T
T
T
A
T
A
T
G
G
T
A
T
G
A
A
A
T
A
28850
A
G
G
G
T
C
C
A
A
C
T
T
C
A
T
T
A
T
T
T
C
A
T
A
T
G
T
G
T
A
T
A
T
T
C
A
G
T
T
T
T
C
C
C
C
C
A
T
C
G
28900 |
var(28899):[T:0.02]
A
A
T
G
C
T
C
T
T
G
G
C
A
A
C
C
T
T
G
T
C
A
A
A
A
A
T
C
A
A
T
T
G
G
C
C
A
T
T
T
A
T
A
G
G
A
G
G
G
T
28950 |
var(28931):[C:0.03]
T
T
A
T
T
C
C
T
A
G
G
C
T
T
T
C
C
A
T
T
C
T
G
C
C
C
C
A
C
T
G
G
C
A
T
A
T
G
T
G
C
C
T
G
T
C
T
T
T
A
29000
T
G
C
C
A
G
T
C
C
T
A
C
G
C
T
G
T
T
T
T
G
A
A
T
A
C
T
G
T
A
G
C
T
T
T
G
T
A
G
T
A
A
G
T
T
T
T
G
A
A
29050 |
var(29012):[T:0.02]
|
var(29013):[A:0.03]
A
T
C
A
G
G
A
A
G
T
G
T
G
A
G
T
C
C
T
A
C
A
A
C
C
T
T
G
T
T
C
T
T
T
T
T
A
A
A
G
A
T
C
A
T
T
T
T
G
G
29100
C
T
A
T
T
T
G
G
G
A
AAAACATTAA TTTTAAAAAA TTACTACTTG TAAGATCTGT
29150
GTGAAATTTC TACCTTCTGA AAATATGAAT TCTTCTCGTT AAAATTTTCT
29200
GGGACTCTAT TTCCTGCTGT TCACTAAAGT GTGTATTTAT GCTCTTAATT
29250
ATAG
A
A
A
G
A
G
T
A
T
T
C
A
A
A
C
G
A
A
A
A
T
G
C
A
G
T
T
G
T
G
A
A
G
A
G
A
A
T
G
C
A
G
T
C
T
C
29300 | Exon 7
K E Y S N E N A V V K R M Q S 320
T
T
C
A
A
C
T
T
G
A
T
T
G
T
G
T
G
G
C
A
G
T
A
C
C
T
T
C
A
A
G
C
C
G
G
T
C
A
A
A
T
T
C
A
G
GTAAA
29350
L Q L D C V A V P S S R S N S 335
TTACACTATG GTCAAAATCT ATTCATTTAT TTGTTTGGTT ACTCATTCAC
29400
TCCACTCTCT AAAAGACTAT TCAGGACCAT ATGGGAAACA GAAGAAACTA
29450
TAAAAGTGAA CACCTGCCTT ACAGGAATTT ATAATAATAT T
C
GAGAGTCA
29500 |
var(29492):[T:0.15]
AGTTACATGT ATTTGAAATA TGAAGTAACA GTGTGCTCAC CAGTCATAGA
29550
GTGTTCTGAA CAAAAGGCCT AATATATCTG AT
G
G
G
G
A
G
A
A
G
T
G
A
C
A
G
T
T
C
29600 |
REPEAT
A
G
A
A
G
A
A
G
G
A
A
G
G
G
G
A
C
A
T
A
T
G
T
G
A
G
A
G
C
A
A
A
G
T
C
C
C
T
G
A
G
G
A
G
C
T
C
G
G
A
29650
G
T
G
A
C
T
T
A
C
A
G
C
C
A
G
G
G
T
A
C
A
A
G
C
A
G
A
G
A
G
G
C
T
G
G
T
C
T
C
A
G
G
T
C
A
A
G
T
A
G
29700 |
var(29667):[A:0.19]
G
G
A
T
A
C
T
T
T
T
T
T
C
A
C
T
G
T
A
A
C
A
A
A
A
G
G
G
A
T
G
G
C
A
G
A
G
T
A
T
A
G
G
A
T
A
C
T
G
A
29750
A
G
C
C
G
C
T
T
A
G
C
T
A
C
C
T
G
A
T
C
T
G
T
G
G
C
T
A
A
T
T
A
C
T
T
A
A
C
C
T
C
T
T
C
T
A
A
A
C
T
29800 |
REPEAT
T
C
A
C
T
C
A
T
C
A
A
A
T
C
A
T
A
A
T
T
G
C
T
C
C
T
C
C
T
C
T
C
A
T
A
G
G
G
C
T
C
T
T
C
A
A
G
A
A
T
29850
G
A
A
A
G
A
A
T
T
C
A
T
G
G
G
A
C
A
T
G
C
T
T
A
G
G
A
C
A
G
A
G
C
TGCTGCA GATC
T
T
T
T
T
T
29900 |
REPEAT
T
T
T
T
G
G
A
G
A
C
A
G
A
G
T
C
T
G
T
C
A
C
C
C
C
G
G
C
T
G
G
A
G
T
G
C
A
G
T
A
G
T
G
T
G
A
T
C
T
T
29950 |
var(29916):[:0.01]
G
G
C
T
C
A
C
T
A
C
A
A
C
C
T
C
C
G
C
C
T
T
T
C
A
G
G
T
T
C
A
A
G
C
G
A
T
T
C
T
T
C
T
G
C
C
T
C
A
G
30000
C
C
T
C
C
C
A
A
G
C
A
G
C
A
G
G
G
A
T
T
A
C
A
G
G
C
A
T
G
C
A
C
C
A
C
C
A
T
G
C
C
C
G
G
C
T
A
A
T
T
30050
T
T
T
G
T
A
T
T
T
T
C
A
G
T
A
G
A
G
A
T
G
G
G
G
T
T
T
C
G
C
C
A
T
G
T
T
G
G
C
C
A
G
G
C
T
G
G
T
C
T
30100
C
G
A
A
C
T
C
C
T
G
A
C
C
T
C
A
G
G
T
G
A
T
C
C
G
T
C
C
G
C
C
T
C
A
G
C
C
T
C
C
C
A
A
C
G
T
G
C
T
A
30150
G
G
A
T
T
A
C
A
G
G
C
G
T
G
A
G
C
C
A
C
C
G
C
A
C
C
C
A
G
C
C
ACAGATCTT ATTTTCCACC
30200 |
var(30167):[G:0.18]
TGAATTGCTC CAAGGAGACA ACCACCTTCT CTGCTCCAAA CCAAGTCCCT
30250
TTTTTCCTTG ATCATCCCTG CAACAGCCGC TTTTCTCTTG CTTGCTATAA
30300
TTTTCCTAGT ACTCTCT
T
AC TGCCAGCGAG GAGCTCCTAT TATTATTTGT
30350 |
var(30318):[C:0.14]
AAAGCTTGTG GGAAGAGGAC CATCTCCTAA ATGCTTTGGA CTGGTCTCGT
30400
ACTTGTTTTC TGTGTGTTAC
T
TTGAGATAC AGATTCATGA CGGCGCTCAG
30450 |
var(30421):[C:0.02]
ATTTTATTTT ACTTTTTAAT GTTTCATGAC ACCCATTCTA ATGTTGATCA
30500
TTTCTTCTCA G
C
C
A
C
A
G
A
A
C
A
G
C
C
T
G
G
T
T
C
A
C
T
G
C
A
C
A
G
T
T
C
C
C
A
G
G
G
A
C
30550 | Exon 8
A T E Q P G S L H S S Q G 348
T
T
G
G
G
A
T
G
G
G
T
C
C
T
G
T
G
G
A
G
G
A
G
T
C
C
T
G
G
T
T
T
G
C
T
C
C
T
T
C
C
C
T
G
G
A
G
C
A
C
30600
L G M G P V E E S W F A P S L E H 365
C
C
A
C
A
A
G
A
A
G
A
G
A
A
T
G
A
G
C
C
C
A
G
C
C
T
G
C
A
G
A
G
T
A
A
A
C
T
C
C
A
A
G
A
C
G
A
A
G
C
30650
P Q E E N E P S L Q S K L Q D E A 382
C
A
A
C
T
A
C
C
A
T
C
T
T
T
A
T
G
G
C
A
G
C
C
G
C
A
T
G
G
A
C
A
G
G
C
A
G
A
C
G
A
A
A
C
A
G
C
A
G
C
30700
N Y H L Y G S R M D R Q T K Q Q 398
C
C
A
G
A
C
A
G
A
A
T
G
T
G
G
C
T
T
A
C
A
A
C
A
G
A
G
A
G
G
A
G
G
A
A
A
G
G
A
G
A
C
G
C
A
G
G
G
T
C
30750
P R Q N V A Y N R E E E R R R R V 415
T
C
C
C
A
T
G
A
C
C
C
T
T
T
T
G
C
A
C
A
G
C
A
A
A
G
A
C
C
T
T
A
C
G
A
G
A
A
T
T
T
T
C
A
G
A
A
T
A
C
30800
S H D P F A Q Q R P Y E N F Q N T 432
A
G
A
G
G
G
A
A
A
A
G
G
C
A
C
T
G
C
T
T
A
T
T
C
C
A
G
T
G
C
A
G
C
C
A
G
T
C
A
T
G
G
T
A
A
T
G
C
A
G
30850
E G K G T A Y S S A A S H G N A 448
T
G
C
A
C
C
A
G
C
C
C
T
C
A
G
G
G
C
T
C
A
C
C
A
G
C
C
A
A
C
C
T
C
A
A
G
T
A
C
T
G
T
A
T
C
A
G
A
A
C
30900
V H Q P S G L T S Q P Q V L Y Q N 465
A
A
T
G
G
A
T
T
A
T
A
T
A
G
C
T
C
A
C
A
T
G
G
C
T
T
T
G
G
A
A
C
A
A
G
A
C
C
A
C
T
G
G
A
T
C
C
A
G
G
30950
N G L Y S S H G F G T R P L D P G 482
A
A
C
A
G
C
A
G
G
T
C
C
C
A
G
A
G
T
T
T
G
G
T
A
C
A
G
G
C
C
A
A
T
T
C
C
A
A
G
T
C
A
T
A
T
G
C
C
T
A
31000
T A G P R V W Y R P I P S H M P 498
G
T
C
T
G
C
A
T
A
A
T
A
T
C
C
C
A
G
T
G
C
C
T
G
A
G
A
C
C
A
A
C
T
A
T
C
T
A
G
G
A
A
A
T
A
C
A
C
C
C
31050
S L H N I P V P E T N Y L G N T P 515
A
C
C
A
T
G
C
C
A
T
T
C
A
G
C
T
C
C
T
T
G
C
C
A
C
C
A
A
C
A
G
GTAAATGGG TCTTCGATAG
31100
T M P F S S L P P T 525
TCACAAGCTT GTCTTTTTTT ATTTTTCAGA AAATACAGCA ACCAAGCAGC
31150
TCTATTATAG ATTGTGGGTT ATAATGGGGA CAGAGGGCAT CATCAGCTGC
31200
CAGATGCAAA TTGCCCCTGT GGAATGGACC CTGCCAAACC ACTTGGTCTG
31250
GGAGTATTTC ATCTGGGGCT AGGATTCATC ACAGATGCCC GCAAGCATCG
31300
GGTTACAGGT CCTTGTGACT GGCAGGCATC TTTGACTCTA ACCTGGAGTG
31350
CATAGTAGTC CTATTTCACC CAATCTCTGA TAAATGGGAA GTTATCTGCT
31400
TATTTGCTTT TACCTTGCTT GCTACTTTTT GAAGGTAAGA AATCAGTCTT
31450
GGATATTTTT GTTTCTGACC TTATATAGCT CAAAGACTAC CA
T
TAGTGAT
31500 |
var(31493):[A:0.01]
GAAAAATTTT CTTTTAACTC CCATATCTCT ATCAGGTGAA GTAAAAGGTA
31550
GGTGATAGTA GTTACTGGCA GTCTAGAATG GAAGTGAGTT AATGTAATAT
31600
CCAGCATTTT TATCAAATAA TACTCACCAA C
A
TCACCTTA ACTACCTGAA
31650 |
var(31632):[G:0.01]
CAGCATCTAC CAATGATACC CACAGGTGTC CTGGAGATCT TGAAATCATC
31700
TCAGGTAGAG GAAGCTTTCA GAACCACAGA GCTTAGTTAC ATTTTCTTTC
31750
AAAAGGCCAA ATTCTCCAAA AA
C
G
T
C
C
T
A
T
G
C
A
A
A
C
A
T
C
C
T
C
G
A
T
T
T
C
T
T
31800 |
NOT SCANNED
C
C
A
T
A
G
G
T
T
T
T
A
T
G
A
T
A
A
G
A
T
C
T
G
T
A
G
A
A
T
G
C
A
A
A
A
T
A
T
T
G
G
A
T
T
A
G
A
C
A
31850
T
T
A
A
G
C
A
G
T
A
T
C
C
A
A
G
T
C
A
T
G
T
A
T
A
A
T
C
C
T
A
T
G
A
G
C
A
G
A
A
T
G
T
C
C
T
T
T
T
G
31900
T
T
T
C
C
T
T
C
A
T
G
T
T
G
G
G
G
A
T
A
A
A
A
T
T
T
T
T
T
A
T
T
A
G
T
A
T
T
G
C
C
A
T
A
T
C
A
T
T
T
31950
T
A
T
T
C
A
T
T
C
A
T
G
A
T
T
A
A
G
T
C
A
A
T
A
A
A
A
A
T
T
T
C
A
G
C
T
G
G
G
G
C
C
A
T
G
G
T
T
G
G
32000 |
REPEAT
C
C
A
G
G
T
G
T
G
G
T
G
G
C
T
T
A
T
G
C
C
T
G
T
A
A
T
C
T
C
A
G
C
A
C
T
T
T
G
G
G
A
G
G
C
T
G
A
G
G
32050
T
G
A
G
T
G
G
A
T
C
A
C
T
T
G
A
G
G
C
C
A
G
G
A
G
T
T
C
G
A
G
A
C
C
A
G
C
C
T
G
G
C
T
A
A
C
A
T
G
G
32100
T
A
A
A
A
C
C
C
T
G
T
C
T
C
T
A
C
T
A
A
A
T
A
A
T
A
C
A
A
A
A
A
T
T
A
G
C
C
A
G
G
C
G
T
G
G
T
G
G
C
32150
G
C
A
T
G
C
C
T
T
T
A
G
C
C
C
C
A
G
C
T
A
C
T
A
G
G
G
A
G
G
C
T
G
A
G
G
C
A
G
G
A
G
A
A
T
C
A
C
T
T
32200
G
A
A
C
C
C
T
G
G
A
G
A
C
A
G
A
C
G
T
T
G
C
A
G
T
G
A
G
C
T
G
A
G
A
T
C
A
T
G
C
C
A
C
T
G
C
A
C
T
C
32250
C
A
G
C
C
T
G
G
G
C
A
A
C
A
G
A
G
T
G
A
G
A
T
T
G
T
G
T
C
T
C
G
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
T
T
C
32300
C
A
C
T
G
G
C
T
G
G
G
C
A
C
A
G
T
G
G
C
T
C
A
C
G
C
C
T
G
T
A
A
T
T
C
C
A
G
C
A
C
T
T
T
G
G
G
A
G
G
32350 |
REPEAT
C
C
G
A
G
G
T
G
G
G
A
A
G
A
T
C
A
C
G
A
G
G
T
C
A
G
G
A
G
A
T
T
G
A
G
A
C
C
A
T
C
C
T
G
G
C
T
A
A
C
32400
A
C
G
G
T
G
A
A
A
C
C
C
C
G
T
C
T
C
T
A
C
T
A
A
A
A
A
T
A
C
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
G
C
32450
T
G
G
G
C
A
T
A
G
T
G
G
C
G
T
G
C
G
C
C
T
G
T
A
A
T
C
C
C
A
G
C
T
A
C
T
T
G
G
G
A
G
G
G
T
G
A
G
G
C
32500
A
G
G
A
G
A
A
T
C
A
C
T
T
G
A
A
C
C
C
G
G
G
A
G
G
C
A
G
A
G
G
T
T
G
C
A
G
T
A
A
G
C
C
G
A
G
A
T
T
G
32550
C
A
C
C
A
C
T
G
C
A
C
T
C
C
A
G
C
C
T
G
G
G
T
G
A
C
A
G
A
G
C
G
A
G
A
C
T
G
T
C
G
C
A
A
A
A
A
A
A
A
32600
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
TTC CAAAACTCTT
C
C
C
A
C
T
T
T
G
T
G
A
C
G
T
G
C
A
G
T
32650 |
REPEAT
T
C
T
C
C
A
G
G
C
A
C
T
G
G
A
G
C
T
A
T
A
A
C
T
G
A
A
C
A
A
A
C
A
G
C
C
T
G
A
G
T
C
C
C
T
T
C
C
C
T
32700
C
A
C
A
C
A
G
T
T
T
A
A
A
T
C
C
T
A
G
T
G
G
A
C
A
G
A
A
G
G
C
A
G
A
C
C
C
T
A
A
A
C
C
A
A
T
A
TTT
32750
AATGTGTCAT TTTTTATCTT TTTTCTACAT GAGCAACCCA AATACACCCG
32800
TTTAGTGCCA GAAATCTCTT TGTGTTTTCA CCTCG
T
TCTG GTTCCTGGTT
32850 |
var(32836):[C:0.11]
CTGCCAGTGA CAGATGTACA GGGATGCAGC TTCTTCAGGG TTCTGAGATG
32900
CTTTCAGTGG GAAAGGGGCG CTTGGATCTA CAATAGATAA TAGAATTTTC
32950
TGTGTTTCTG CTCCCAAAGA TGATCCTGCC AGGTACTAAG CTAGTAAATG
33000
AACACGCTGA GTTTCTCCTT GCAAATTTAA ATAAGTCTTC TGCTTGCTTT
33050
TATCATCAAA AAGTCCTAAC TCTATACCAA AAT
G
TGAGTT TTCTAATTTG
33100 |
var(33084):[A:0.07]
CCATACCATA GAAGAAGGGT GTGTATGCAG TAAGTACAAA AGGAAAATAA
33150
ATGTCTTCCT TTCAGTGAAA GAGCTCTTAG ACCCACTGCT TTTTATTCAC
33200
TGTGCTGCTT GAAGTGAGGT TAGAAAAG
G
A
A
A
G
C
T
C
A
C
T
G
G
G
C
T
A
A
G
A
G
T
33250 |
REPEAT
|
var(33250):[A:0.01]
C
A
G
G
A
G
A
C
C
C
A
G
G
T
C
T
A
G
T
C
C
T
G
C
T
T
G
T
G
C
C
G
G
T
C
A
C
T
A
T
A
T
G
G
G
T
G
A
C
T
33300
T
T
G
G
G
A
A
A
G
T
C
A
T
T
T
G
C
C
T
C
T
C
C
A
G
A
G
T
T
C
A
T
T
C
T
C
C
T
C
A
A
T
T
A
T
A
A
A
T
G
33350
A
A
A
A
T
G
T
T
A
C
A
A
C
T
G
A
A
A
A
T
T
T
A
T
A
T
A
T
T
A
T
C
A
G
C
T
C
T
A
G
T
A
T
G
T
T
T
C
T
A
33400 |
var(33371):[C:0.27]
G
T
A
T
T
GCATT CGTTTCTCCA CTTCGTAACT TTCATGGTTT TTCCAGTGGT
33450
CAGATTTGGG CAGAAAGCAC TGATTCAAGA ACACAGATTT CCAAGTAGAG
33500
AGGTGCAGGG TAAATAAACC TCCATGTAAG CCCGCGGTGA GCGCAGACTG
33550
TGAGTGACGA ACACGGTGTC AGTGTAAGCT GGAGGTGGTG GGCCAG
G
A
G
G
33600 |
REPEAT
A
T
T
A
A
A
C
A
G
G
G
T
A
A
G
G
C
A
G
C
T
T
A
C
C
A
C
T
G
T
G
C
C
T
G
G
C
G
A
T
G
C
G
C
A
G
A
G
T
A
33650
A
G
T
G
C
T
C
A
G
T
A
A
A
C
G
G
T
A
G
C
T
G
C
T
G
T
T
ATT AGCACTGTTA TTATCATTGT
33700
CA
G
CAAAGAA CACCTAGACA GCCTTGAGCA CTGGAAGGCA CCTCAGAGAC
33750 |
var(33703):[A:0.11]
TGTCACAGGG GTTCCTTGCT AGGATTCCAA GGACCCCAGT TTCAGCAGCT
33800
TCACGAACAC CCTGAATTGC ACACAGATGG CGTGTGTGTG CACATCCTAT
33850
ATTTCTTACA CCTTTCAGTA GAGAGGGTCC CTAGTTTCCT TGGCTTCCTC
33900
AGAGAAAATG TAACAAATGA GCAC
A
GTGCC TGGTCCAGAG GGTGGCCTAC
33950 |
var(33925):[G:0.07]
CTTAGGGCCA GGTGTGCTGA CGGAGGTACC TTGAGCTGAT ACTCATTTCC
34000
CTCCCTCCTC AGAACTGTCT TCTCAACCAC CTTCTCTCTC CTACAAAGAT
34050
ATGCCAAGTG CTCTTTAGGG ACAGTACCAA CACTTGACAA
A
T
T
C
A
G
C
T
C
A
34100 |
REPEAT
G
C
A
T
G
A
A
T
G
T
C
A
T
T
G
A
G
C
C
C
A
T
G
C
C
C
C
G
T
A
C
C
A
A
G
G
C
C
C
A
G
G
C
T
A
G
C
G
A
G
34150
T
G
T
A
A
G
G
A
G
T
A
C
A
A
A
A
A
C
A
A
G
T
G
G
G
T
G
T
G
G
T
C
G
C
T
G
C
C
C
T
T
G
G
G
A
C
T
C
A
C
34200 |
var(34159):[A:0.02]
A
T
T
C
T
A
G
T
G
G
A
G
A
A
G
T
C
A
A
A
C
A
G
A
C
C
C
A
G
C
T
C
A
G
A
T
A
CAG AGCGGCGCAG
34250 |
var(34208):[C:0.08]
GGCAGAGTGC TGAGTCTAGG ATTACAGTGC AGGCTCATGG AAGGAGGTGG
34300
AATTTGTGCT GGGCCTATGT CAGAAACTCA CAAGCAGGGA GAAGCACGTG
34350
GGGAGGTCAG CAGTCCAGGC AGAGGCAGGA GCATCATGTC AGCAGATCGG
34400
TGGGAAATCT GGTGGGACTG GAGTCTCTGG AGTGGAGACA GGGAGGAAAC
34450
AGTGAAAGGA AGATCAGAGA CAAGAGGGTA GGGCAGAGCT GTGGCTAGCT
34500
TCTGAATACT GAACCTGAGA GGTTTGAGTT TATCAG
G
TAA AGGAGGAGGA
34550 |
var(34537):[T:0.03]
CCCTTCACAG ATGCTGTTCA GAGTCGTGGG ATCCCGCTGG GAAGTGTGGC
34600
TGAGCTTTGC TGTGTTGTTC ATCCACTTCT GTTTTCTGAC TTGGTGTTAG
34650
CCACA
T
T
T
T
T
T
T
A
T
G
G
T
A
A
A
A
T
T
C
A
A
A
A
A
C
A
T
A
A
A
A
T
T
T
A
C
C
A
T
T
T
C
A
A
C
34700 |
REPEAT
C
A
T
T
T
T
T
A
C
A
G
T
G
G
C
A
T
T
A
T
C
T
A
A
C
A
T
T
C
A
C
A
G
T
G
T
T
A
T
G
C
A
A
C
C
A
T
C
A
C
34750 |
var(34731):[:0.02]
C
A
C
C
A
T
C
T
A
T
C
T
A
T
A
T
A
A
C
T
G
T
T
T
T
A
A
T
C
T
T
G
C
A
A
A
A
C
T
A
A
A
A
C
T
C
T
G
T
A
34800
T
C
C
A
T
T
A
A
A
C
A
C
C
A
A
C
T
C
C
C
C
A
G
C
T
C
C
C
C
T
C
C
C
A
G
C
C
C
C
G
G
A
C
A
A
C
C
A
C
C
34850 |
var(34816):[T:0.01]
A
T
T
C
T
A
C
T
C
T
C
T
G
T
T
T
C
T
G
T
G
A
C
T
C
T
G
A
C
C
A
G
T
C
T
A
G
G
T
A
C
C
T
C
A
T
G
T
G
A
34900 |
var(34891):[T:0.02]
G
T
G
G
A
A
C
C
A
T
G
C
A
G
C
A
T
T
T
T
T
C
T
T
T
G
T
G
G
C
T
G
G
C
T
T
C
A
T
T
C
A
C
T
T
A
G
G
A
A
34950 |
var(34909):[G:0.02]
A
T
G
T
C
C
T
C
A
A
G
C
T
T
C
A
T
G
C
A
T
G
T
T
G
T
A
G
C
A
T
G
T
G
A
T
G
T
G
A
T
T
C
C
C
T
T
C
C
T
35000
T
T
T
C
A
A
G
G
C
T
G
A
C
T
A
T
T
C
C
A
T
T
G
T
G
T
A
G
C
T
A
G
A
C
C
A
C
A
G
T
T
G
G
G
T
T
A
T
C
C
35050
A
C
T
C
A
T
C
T
G
C
T
C
A
T
G
G
G
T
G
C
C
T
G
G
C
T
T
A
C
T
T
C
C
A
C
C
T
T
T
T
A
G
C
T
A
T
T
G
T
G
35100
A
A
T
A
A
T
G
C
T
G
C
A
G
T
G
A
A
C
A
C
G
T
G
G
G
T
A
G
A
A
A
T
A
T
T
T
C
T
T
C
A
A
C
A
C
C
C
T
G
T
35150 |
var(35139):[C:0.04]
T
T
T
A
G
T
T
C
T
T
T
T
G
G
G
T
A
T
A
T
A
C
T
C
A
G
A
A
A
C
G
G
A
A
T
T
G
C
T
G
G
A
T
C
A
T
A
T
G
G
35200
T
A
A
T
T
C
T
A
T
C
T
T
T
A
A
T
T
T
T
T
T
T
G
A
A
G
A
A
T
C
A
C
G
A
T
T
T
T
T
T
T
T
T
T
T
T
T
T
T
T
35250 |
REPEAT
T
T
T
T
T
G
A
G
A
C
A
G
A
C
T
C
T
C
A
C
T
C
T
A
T
C
A
C
C
A
G
G
C
T
G
G
A
G
T
G
C
A
G
T
G
G
C
A
C
G
35300
A
T
C
T
T
G
G
C
T
C
A
C
T
C
T
G
C
A
A
G
C
T
C
C
G
C
C
T
C
C
T
G
G
G
T
T
C
A
A
G
T
G
A
T
T
C
T
C
C
T
35350
G
C
C
T
C
A
G
C
C
T
C
C
T
G
A
G
T
A
G
C
T
G
G
G
A
T
T
A
C
A
G
G
C
A
C
C
C
A
C
C
A
C
C
A
C
G
C
C
T
G
35400
G
C
T
A
A
T
T
T
T
T
G
T
A
T
T
T
T
T
A
G
T
A
G
A
G
A
A
G
G
G
G
T
T
T
C
A
C
C
A
T
G
T
T
G
G
C
C
A
G
G
35450 |
var(35446):[G:0.01]
C
T
G
G
T
C
T
T
G
A
A
C
T
C
C
T
G
A
C
C
T
C
A
G
G
T
G
A
T
C
A
C
C
T
G
C
A
T
C
A
G
C
C
T
C
C
C
A
A
A
35500
G
T
G
C
T
G
G
G
A
T
T
A
C
A
G
G
T
G
T
G
A
G
C
C
A
C
C
G
C
A
C
C
T
G
G
C
C
C
A
C
T
A
T
A
C
T
C
T
T
T
35550 |
REPEAT
A
T
A
G
G
A
G
C
A
G
C
T
G
C
A
C
C
A
T
T
T
C
A
C
A
T
T
C
C
C
A
C
C
A
G
C
A
G
T
G
C
A
C
A
A
G
G
G
C
T
35600
T
C
A
T
T
T
T
T
T
C
C
A
C
A
T
C
T
T
T
G
T
C
A
A
T
A
T
G
T
G
T
T
A
T
T
T
C
T
T
T
T
T
T
T
T
T
T
T
T
T
35650
A
A
T
C
A
T
A
G
G
C
A
T
C
C
T
A
A
T
G
G
G
T
A
T
G
A
G
G
T
G
G
T
TTAGCCAG ATTTGAAAGA
35700 |
var(35654):[T:0.05]
|
var(35655):[G:0.04]
AGAAAAGTTT AAAGGGTGGC ATAGGATAAT TAACTTAATG TTTGGCATAA
35750
AGCCCTGCTT TTTTGCCATG CTGTATTTTT TTCTCTTGCT TTTGATCTAG
35800
AATTACTTAC CTGTGTGTTT CTCTCTATGC AG
A
T
G
A
A
T
C
T
A
T
A
A
A
A
T
A
T
A
35850 | Exon 9
D E S I K Y 531
C
C
A
T
A
T
A
C
A
A
T
A
G
T
A
C
T
G
G
C
A
T
T
C
A
G
A
T
T
G
G
A
G
C
C
T
A
C
A
A
T
T
A
T
A
T
G
G
A
G
35900
T I Y N S T G I Q I G A Y N Y M E 548
A
T
T
G
G
T
G
G
G
A
C
G
A
G
T
T
C
A
T
C
A
C
T
A
C
T
A
G
A
C
A
G
C
A
C
A
A
A
T
A
C
G
A
A
C
T
T
C
A
A
35950
I G G T S S S L L D S T N T N F K 565
A
G
A
A
G
A
G
C
C
A
G
C
T
G
C
T
A
A
G
T
A
C
C
A
A
G
C
T
A
T
C
T
T
T
G
GTAAG ATACCCTGGA
36000
E E P A A K Y Q A I F 576
AGGACTCAAC GCCTAGCAAC CTTGAACTTT CTTACTTGTG AGAAGGACAT
36050
AGTGGAATCT TAAAATTTCT CTGATAATTC TTCTTGAAAG TTTTCTTATG
36100
TTACTTCTGC AAAATATCTT TGTAATTTCC ATA
T
A
A
T
T
C
C
T
T
T
G
T
C
A
T
T
T
36150 |
REPEAT
A
T
T
T
A
T
T
T
T
T
A
A
T
A
T
G
G
A
G
A
T
A
A
T
C
A
C
A
G
T
A
T
T
T
A
A
T
T
T
A
T
G
G
A
T
T
T
G
T
T
36200
G
T
G
A
A
A
A
T
T
A
A
A
T
G
A
G
T
T
G
A
T
A
T
G
T
A
T
A
A
A
A
A
G
C
T
T
A
G
A
A
C
A
C
T
G
C
C
T
G
G
36250 |
NOT SCANNED
C
A
C
A
T
A
G
T
A
A
G
T
T
C
T
A
T
A
A
A
A
A
G
T
G
T
T
A
A
A
C
T
T
T
C
A
T
C
A
T
C
A
T
C
A
T
C
A
T
C
36300
A
G
T
A
T
T
A
C
T
T
C
T
C
A
G
A
C
C
C
A
G
A
A
G
A
A
A
T
A
G
C
T
G
T
G
T
C
A
G
G
C
C
C
T
C
A
T
C
G
A
36350
A
G
G
A
G
A
T
C
C
T
G
T
A
A
A
A
G
A
T
A
G
A
A
G
A
C
T
G
T
G
C
C
C
T
C
C
A
C
A
G
C
A
C
T
T
C
T
G
T
A
36400
A
T
A
A
A
A
T
C
A
A
G
A
G
G
G
C
T
A
T
C
T
C
T
T
A
T
A
G
G
G
T
T
C
T
A
T
G
G
T
G
C
A
G
C
C
C
A
T
A
A
36450
T
G
C
T
A
A
T
C
C
C
A
A
A
G
T
A
C
A
G
T
C
T
G
G
A
A
A
A
A
G
T
C
A
T
G
A
G
G
C
C
A
A
A
A
C
G
A
C
T
T
36500
G
A
T
T
A
A
G
A
A
C
T
C
A
G
C
T
T
T
C
T
A
A