LPA Color FASTA
The longest form of insertion/deletion sites is shown in the FASTA sequence and contain a '-' as the alternate allele in the variation tag.
*Display courtesy of
GeneSNPs
AAAGATGTGG AGGGTTGGAA GCAAGAGGGG GGCCAACGCG CACGGGGAGG
50
AAGCATTTGG GCAGTGACTC CGCAGACCCA GGCTCAGGTT GAACTAGAC
A
100 |
REPEAT
A
C
C
T
C
C
T
T
A
C
A
C
C
T
C
A
G
T
T
T
C
C
T
T
A
A
C
T
G
T
A
G
A
G
C
A
G
G
A
G
T
G
A
T
G
G
A
A
C
T
150
G
C
C
T
G
T
T
T
C
A
T
A
G
G
A
C
T
G
T
T
G
T
G
A
G
G
A
T
G
A
A
G
T
G
A
G
A
T
A
C
A
C
C
A
C
A
T
T
A
T
200
A
A
G
C
T
T
G
T
G
C
C
T
G
G
A
A
A
G
G
A
T
A
A
T
G
C
T
T
A
G
T
A
A
A
T
G
A
T
G
A
C
T
A
T
T
C
T
T
T
T
250 |
REPEAT
T
T
A
T
T
G
C
A
A
T
A
A
A
A
T
G
T
A
C
A
C
A
G
C
G
T
A
A
G
A
G
T
T
A
C
T
A
T
T
T
T
A
A
C
C
A
T
T
T
T
300 |
var(275):[A:0.01]
T
G
C
A
G
G
G
T
A
C
C
A
C
C
A
A
G
T
G
G
C
A
T
T
T
A
G
T
A
C
A
T
T
C
A
C
A
G
T
G
G
T
G
T
G
C
A
A
C
C
350
A
T
C
A
T
C
A
T
A
T
T
T
C
C
A
G
A
A
T
A
T
T
T
T
C
C
T
C
A
T
C
C
C
C
A
A
A
G
G
A
A
A
C
C
T
C
A
T
G
C
400
T
C
A
T
T
A
A
T
C
A
G
T
A
G
C
T
C
T
C
C
A
T
T
AAA
A
TAT TAGTTATGAA GATCATAGCA
450 |
var(421):[T:0.10]
|
var(427):[G:0.10]
CTATACAAAA CTCATTATGT AATGTTGAGT GAAAAAATCA GGGTGTGAAA
500
TTTTGTGATA TGATGTAATT AGTGAAAGAA GCATACAAAA AGTCTGAAAA
550
TATAAAAACA ATAGCAATTG CATTTCTCAG ACTCTACATT TAAACATTAT
600
TCTTTATGGT TTTAAAAGCA AAGAAAAAGG TAAAGAAACA ACAACCAACC
650
GCAAAGCACC ATGACAAAGC TCAGATTGTT AAATCCAGGT TTTTGGAACA
700
TAGACTCTTA TATGACGTTT ACACTCTCCA GGGTTCAGAG AGTCTGGCAG
750
CATTGGGAGC TGCCTTGTGT TCTACAGCCT CACGGACAGA CAGGAGGTCC
800
ATCACCACTG CTCTGTTCTT CTGGAGTTTC CTTGTGAACA TGTTGTGGA
C
850 |
var(850):[T:0.04]
GTAGTTACCA TTTCTTTCAT CTTTTTAAAC AC
A
G
G
T
A
C
C
T
T
T
G
G
G
G
C
T
G
G
900 | Exon 1 |
UTR
C
T
T
T
C
T
C
A
A
G
G
A
A
G
C
C
C
A
G
C
T
C
C
C
T
G
T
G
A
T
T
G
A
G
A
A
T
G
A
A
G
T
G
T
G
C
A
A
T
C
950
G
C
T
A
T
G
A
GTT TCTGAATGGA AGAGTCAAAT CCACTGAGCT CTGTGCTGGG
1000
CATTTGGCTG GAGGCATTGA CAGTTGCAAG GTAAGAAAAG ATCAAGAGAC
1050
CAAAGTTAGT CTTGTGCTCT CCTGTCTCAG TCTCAGTCCC TTAGACTTGA
1100
GTCCCAAAGT AGCGAATTCA AGTAGGATTT AATCAATGGA AGACCCCAGT
1150
CTAAGTGTTG CTCAGAAACT CCCTAGATCT GTCCCAAATG TATATTCAGA
1200
TCATCCAAGG GGACTTCTTG GGGCTTGAGT TCCAGATCAG CAGCAAGGGA
1250
GCCATAAGTG CCATAACTAC CTCAGACCAC TCACCCTCCT GGGGTGTCCC
1300
GGTGGCCAGG GACTAAAGTG GTGATTTTTC TGGTAGGGAA GGAGGTAGAG
1350
GGTACAGGAC AGAGACTAAC T
G
CACACAAT ATCTGAGACT GGAGCTCAGA
1400 |
var(1372):[A:0.01]
TATTGCTGAT GATCAGAGTT GGCGTGTCTC CCCAATTGAT TTACAACTGG
1450
GGCTTGGATA CTGTTTTAAA CGGGAGGAGC CTCCTAACCA TCTTGACACA
1500
ACCACTGACG TGACTACACT AGAGATAGAC TCTTTCCACT TAATTCTACC
1550
ACTCTTGCTT TACTTCATGA GAACGAAAAT GTAAGATTGC ACCATGAATT
1600
CATTTGCGGA AAGATTGATA CTATGCTTTT ATTTTATTTT ATTTTATTTT
1650
ATTTTATTTT ATTTTATT
T
T
A
T
T
G
A
G
A
C
T
C
T
C
A
C
C
C
C
G
G
T
T
G
A
A
G
T
G
C
A
C
1700 |
NOT SCANNED
|
REPEAT
T
G
A
C
G
T
G
A
T
T
T
T
G
G
C
T
C
A
C
T
G
C
A
A
C
T
T
C
C
A
C
C
T
C
C
T
G
G
G
T
T
C
A
A
G
T
G
A
A
T
1750
A
C
T
C
C
A
G
C
C
T
C
C
C
T
A
G
T
A
G
C
T
G
G
G
A
T
T
A
C
A
G
G
T
G
C
C
C
A
C
C
A
C
C
A
C
G
C
C
T
G
1800
G
C
T
A
A
T
T
T
T
T
G
T
A
T
T
T
T
T
A
G
T
A
G
A
G
A
T
G
G
G
G
T
T
T
C
A
C
C
A
C
A
T
T
G
G
C
C
T
G
G
1850
C
T
G
G
T
C
T
C
A
A
A
C
T
C
C
T
G
A
C
C
T
T
G
T
G
A
T
C
C
A
C
C
T
G
T
C
T
T
G
G
C
C
T
C
C
C
A
A
A
G
1900
T
G
C
T
G
G
G
A
T
T
A
C
A
G
A
G
T
T
G
A
G
C
C
A
C
C
G
C
A
C
T
C
G
A
C
C
C
T
A
T
G
T
T
T
T
A
T
T
T
T
1950
T
A
A
A
A
A
T
A
T
T
T
A
T
T
T
A
T
T
T
A
T
T
T
A
A
G
C
C
A
C
A
A
C
T
A
C
T
A
G
A
A
T
A
G
G
A
A
G
G
A
2000
T
T
G
A
T
A
T
T
T
T
A
T
T
A
A
T
T
T
T
A
T
T
T
G
G
T
A
T
T
T
A
T
T
A
T
T
T
T
T
T
T
T
T
C
T
T
T
C
C
T
2050 |
REPEAT
G
A
G
A
C
A
T
T
C
T
T
G
C
T
C
T
G
T
C
A
C
C
C
A
G
G
C
T
G
G
A
G
T
G
C
A
G
T
G
G
C
A
C
A
T
T
C
T
T
G
2100
G
C
T
C
A
C
T
G
C
A
A
C
C
T
C
C
A
T
C
T
C
C
T
G
T
G
T
T
C
A
A
G
C
A
A
T
T
C
T
A
G
T
G
C
C
T
C
A
G
C
2150 |
var(2130):[G:0.49]
C
T
A
C
T
T
A
G
T
A
G
C
T
G
G
G
A
T
G
A
C
T
G
G
C
A
T
G
T
G
C
C
T
C
C
A
C
A
C
C
C
A
G
C
T
A
A
T
T
T
2200 |
var(2179):[C:0.03]
T
T
G
T
A
T
T
T
T
T
T
G
T
A
G
A
G
A
C
A
G
G
G
T
T
T
T
G
G
C
A
T
G
T
T
G
C
C
C
A
G
G
C
T
T
G
T
C
T
C
2250
A
A
A
C
T
C
C
T
G
G
C
C
T
C
A
G
G
T
G
A
T
C
C
A
T
C
T
G
C
C
G
T
G
G
C
C
T
C
C
C
A
A
A
A
T
G
C
T
G
G
2300
G
A
T
T
A
T
A
G
G
C
A
T
G
A
G
C
C
A
C
C
A
C
C
C
C
C
TCCT GGAAGGATTG ATATCTTATA
2350
ACATAATTTA TAATTACAGA AAACATGTGA GTTCACTAGG AATAAATAAA
2400
TTTTGAAGAT AATAAAAGAT TTTCACTTAT GTTGTCATTT CGGCACAGTT
2450
TGGTATAGGA TGTGGAGATG TTAACATTTA TACCTAGCTT GCTCGTAAAC
2500
TAAGACCTGA AAGGGTTGTG TCTATCAGCT GCACCCCTGG GTAGCGACAC
2550
AACCTCGGGA AGGCCTCAGC CCCCTCCTCG TACAGCACTG CCTGTTGGAA
2600
AGCTTGAGGG AGGCTATGGA TGTGCAGCAC TTGGCAGAGG GTCTGGTCAT
2650
GGAAGTTACC AGCAAATATG AGCTACTTTT ATGATTTTAT TTTATCCAAA
2700
AGAAAGAGAA TGAAAGAAGA GGGGAGGAAA CAAGACTAAT CAGGAAAGAT
2750
GAAGGTCTAG GGGTGAGGGA AGGAGTAAGG AGACATAAAG GCAATGTGGA
2800
GCAGCTGAG
G
GGGGAAATGG CTTTCACCAC TT
C
CCAGCAT CTATTGACAT
2850 |
var(2810):[A:0.01]
|
var(2833):[T:0.01]
TGCACTCTCA AATATTTTAT AAGACTCTAT ATTCAAGGTA ATGTTTGAAC
2900
CCTGCTGAGC CAGTGGCATG GGTCTCTGAG AGAATCATTA ACTTAATTTG
2950
ACTATCTGGT TTGTGGGTGC GTTTACTCTC ATGTAAGTCA ACAA
C
GTC
C
T
3000 |
var(2995):[T:0.10]
| Exon 2 |
UTR
G
G
G
A
T
T
G
G
G
A
C
A
C
A
C
T
T
T
C
T
G
G
G
C
A
C
T
G
C
T
G
G
C
C
A
G
T
C
C
C
A
A
A
A
T
G
G
A
A
C
3050 |
var(3023):[A:0.36]
M E 2
A
T
A
A
G
G
A
A
G
T
G
G
T
T
C
T
T
C
T
A
C
T
T
C
T
T
T
T
A
T
T
T
C
T
G
A
A
A
T
C
A
G
GTAAGACA
3100
H K E V V L L L L L F L K S 16
TAGTTTTTTT AAATTATAAG AATTATTTTT TCTCCCACAA TGTAGTAAAA
3150
ATACATATGC CATGGCTTT
A
TGTGCAATTC ATTTAATTTT TGATTCATGA
3200 |
var(3170):[T:0.38]
AATTCCCAGT TCAAAATCTT GTATATGATT GAAAAATTCT TAAAAAAATA
3250
AGTTTAATTT CCC
C
G
TGAAG ACTGTCACGG TGCTGGAATG AATGGGCAGA
3300 |
var(3264):[G:0.10]
|
var(3265):[:0.01]
AAAAATAATG GTTGATTTTT CTAATCTAAA AGAGTGTGCC TACATGATGG
3350
CCAGTCTGGC TGAAAAATAA ATAGCCATTG TAGCTAACTA TGCAAAGGAT
3400
GGCTAAGCTC TTC
G
CTTGGT TCTCAGTTTC ATTAATTTAT ATCATCTCTG
3450 |
var(3414):[T:0.03]
TTCAGGTGCC ATGCTCCCCT CACTAGCAAG TTGAAACAAT GAAATAACTC
3500
TTTGAATATG TTTGGTTCCT TGACCTGTTC ATGGAGTGGG ACTCAGCATT
3550
TCTCTCTTTG TTATGGCCTG AGTAAGGCTT TCCATCGGTA TACATTTGCT
3600
TCTTATCCCT GGAGAAATTA TACACATCCA TTTGCCAGAT GATATAC
G
CA
3650 |
var(3648):[A:0.42]
TATAATGATT CAACAAATAC TCAGGGTATT TGTTG
A
GTGG GTTAGGTCCC
3700 |
var(3686):[G:0.01]
CACATTTTTA TACATACATA CACACATACA CACCGTGTGT GATTGTGAAT
3750
GTAAGTGTGT GTC
C
T
T
T
A
C
A
A
A
T
A
C
T
A
G
C
T
T
A
T
T
T
A
G
C
T
C
A
T
G
G
T
A
T
A
G
G
3800 |
REPEAT
T
A
G
G
G
T
A
G
C
A
T
A
G
T
C
A
T
C
C
C
C
A
T
T
T
T
A
T
A
A
A
C
A
A
A
G
A
A
A
T
C
T
A
G
A
C
T
T
A
G
3850
G
A
A
A
A
T
C
A
T
G
T
T
A
T
T
T
G
T
C
T
C
G
T
G
A
C
C
A
A
A
T
T
C
C
C
A
A
A
T
C
A
A
G
G
A
A
A
T
A
A
3900
A
G
A
A
A
C
C
T
G
G
A
T
T
T
A
A
G
C
C
A GATTTCCAAG AAAAAATCTA GGGCTCTTCT
3950
CACTTTTTCA TCTTTGTTCC AACATTTGAA AAAATAAATC TAAACACATT
4000
CCAA
T
G
T
A
A
C
T
G
A
A
G
A
G
C
A
G
G
T
T
A
A
T
T
G
T
T
T
G
C
C
A
C
T
T
G
C
A
G
A
A
T
C
C
A
A
T
4050 |
REPEAT
T
A
A
G
A
A
G
A
G
A
G
A
A
G
T
C
T
G
G
T
A
T
A
A
A
G
A
A
A
G
T
G
A
T
T
T
G
C
T
T
C
C
A
A
A
G
C
T
A
G
4100
C
T
T
A
G
G
G
G
A
A
G
A
A
A
T
G
C
A
G
C
A
G
T
C
C
T
G
C
C
G
T
A
C
C
A
C
T
T
C
A
C
T
T
T
A
G
G
A
G
C
4150 |
var(4134):[T:0.10]
A
G
A
A
A
G
T
G
G
C
A
C
T
T
T
T
A
A
A
A
G
G
C
AACAGAG GAGGCGAGCA AGGATTCAGG
4200 |
var(4173):[G:0.01]
GGTCCATGCT AGCTTGGGCA CCTTATCCAC CAGGTAGTTG AGCAGTTGCC
4250
TGCTGGTGCC TTTGTGAGCA GGGTGTTGTC CCTTGAGGCA AATCTCTGGA
4300
GGGTGAGAGT TTTGTAGTGG GCATGCTTTG GTTTATAAAT CACCTGTGAA
4350
CTCAG
G
A
G
T
T
C
C
A
T
C
T
T
G
A
A
G
C
A
C
A
T
A
C
A
T
A
G
T
T
A
G
A
T
G
A
A
C
T
T
G
C
C
C
T
G
4400 |
REPEAT
|
NOT SCANNED
C
A
G
G
G
A
G
A
G
T
C
T
G
A
T
G
A
A
A
G
G
G
A
G
G
T
A
G
A
T
G
C
T
T
G
C
A
A
T
T
T
A
A
T
C
T
A
T
A
A
4450
A
T
T
A
C
C
A
G
A
T
A
A
A
A
T
T
T
T
A
C
A
A
G
T
T
G
A
C
T
T
T
A
A
A
G
T
C
A
A
A
C
A
C
A
T
T
T
G
A
A
4500
T
T
T
A
G
T
G
G
A
A
G
C
C
A
T
T
C
A
A
G
A
A
A
A
T
A
T
C
A
A
A
G
A
A
A
A
T
A
C
A
G
A
G
C
A
G
G
A
G
A
4550
A
G
A
T
T
A
A
G
C
A
A
A
G
A
G
T
T
T
T
T
T
G
G
G
G
A
A
A
T
T
G
G
T
G
T
C
T
A
T
G
T
C
T
G
T
G
T
G
T
G
4600
T
A
G
G
G
A
G
T
G
C
A
G
G
G
G
A
T
A
T
G
A
A
T
A
T
T
C
T
A
T
T
T
C
A
G
C
C
C
A
T
G
G
A
A
A
C
T
A
G
G
4650
A
T
G
T
A
G
A
T
C
A
C
T
G
T
G
A
A
C
T
T
A
T
T
C
A
G
C
A
G
G
C
T
A
C
A
C
C
C
A
A
A
G
G
C
T
A
G
A
A
C
4700
A
A
A
C
T
T
C
T
C
T
G
C
C
A
C
A
G
G
A
T
T
A
A
C
A
T
A
T
G
T
T
T
T
A
A
T
C
G
A
C
C
T
G
G
G
G
G
G
C
A
4750
C
A
T
T
C
T
C
T
G
A
T
A
A
G
C
T
C
T
T
T
T
G
G
A
A
A
G
C
C
A
G
G
C
T
T
T
C
T
G
T
G
G
A
C
G
T
G
T
T
A
4800
T
C
T
T
T
C
C
A
A
T
G
T
G
T
G
C
T
G
G
A
A
T
G
C
C
C
G
G
G
G
A
G
A
G
G
A
A
A
A
A
G
T
T
T
C
T
T
T
T
A
4850
C
A
G
C
C
A
T
G
C
T
C
A
G
T
G
A
G
A
A
G
C
G
G
A
G
A
A
A
C
A
T
C
T
T
C
T
A
T
T
C
A
C
A
A
A
T
T
G
C
T
4900
A
A
G
T
C
T
T
T
T
A
C
A
C
A
T
G
C
A
A
A
T
A
T
G
C
A
T
A
C
A
C
A
T
T
C
A
C
A
C
A
C
C
A
C
A
G
T
G
A
G
4950
G
A
A
G
A
A
A
T
T
C
T
C
A
C
A
C
C
A
T
T
A
A
T
A
A
A
A
T
A
C
A
T
T
T
A
C
T
T
C
A
G
T
A
G
C
A
A
T
A
T
5000
A
C
A
T
C
T
A
C
A
T
T
T
T
G
C
C
T
A
T
A
A
T
A
T
A
A
A
A
G
T
A
T
T
T
T
T
C
C
T
A
T
T
A
A
A
A
G
A
T
T
5050
T
G
T
T
T
A
A
T
G
T
T
T
C
T
T
C
A
C
C
A
A
C
A
A
A
T
A
A
A
C
C
C
T
A
T
T
A
A
A
T
C
C
C
C
A
T
T
G
C
C
5100
A
T
A
T
G
A
G
C
C
C
T
G
G
A
G
G
T
G
A
A
T
C
A
G
A
G
A
A
A
C
A
A
A
A
G
G
A
T
T
G
T
G
G
A
A
A
A
A
T
C
5150
A
T
C
A
G
G
T
T
A
A
A
A
A
A
A
G
A
A
A
A
A
T
T
G
A
T
T
C
T
G
T
T
T
T
G
G
G
A
T
A
T
T
T
C
C
T
A
G
C
A
5200
A
C
A
T
G
A
G
C
T
G
G
G
G
A
G
G
G
G
A
T
C
T
C
A
G
C
A
G
T
G
A
T
G
C
T
C
T
A
T
G
A
A
G
C
A
T
A
A
T
A
5250
A
A
A
T
G
A
C
A
C
A
G
T
T
A
C
A
G
G
T
A
A
C
T
T
A
G
T
T
A
A
A
G
G
G
G
G
A
A
A
T
A
A
A
T
G
G
A
A
G
T
5300
T
T
C
C
T
C
T
T
T
T
T
G
AATATCAA TTGTAGCCTG CTCTGCTACA TTTCAAAAAC
5350
ACTCTTCAAA ATGTTTAACT GAACTCACTG TAGGAAGCAC CTTATTAATT
5400
TATTGTGTGT TTTGAAGTCA CACTGTGAGC TATAGAATTT AC
T
CAAGCAC
5450 |
var(5443):[C:0.33]
AACTCTTCCT GGAAAAGAGA GTTCAAATGA GAAACAGTGC
A
GGGTGAAGA
5500 |
var(5491):[G:0.11]
CATGGATATG GGCCTAAAAT ATCTATTTCT CAATGATATT TTGATATATC
5550
TATCAAGTGC TTTTTAGTGG ATTAGGTTCA GAATGCATCA GCCA
G
TGCCT
5600 |
var(5595):[A:0.32]
GTTCAATAAT CCAGTTTTCC AGCATAGAGC ATATTAAATT GAGGAAGGAC
5650
AAAGTCACAG AGGTGGGGAG CAGGTGGACT GTGGCCAAGG ACTTTGCATG
5700
AAACAGTGAG CGTGCATCCT CCTCCTTGCC CTGCCCTCAT GGTCTGTGTA
5750
CTCTCAGGAG GTCAGGACAG GCCTTTCTGA GAATGAGAAT CTGTTCATCT
5800
G
C
C
T
T
T
C
T
A
C
T
G
G
A
T
A
C
T
T
G
T
C
A
T
C
G
G
C
A
T
A
C
A
A
A
C
A
C
A
T
G
T
T
C
T
C
T
G
C
A
5850 |
REPEAT
|
var(5829):[G:0.16]
G
T
G
T
G
T
C
A
T
C
T
T
T
C
A
G
A
A
C
C
T
C
C
C
C
T
G
A
C
C
C
T
G
T
A
T
T
C
C
C
T
A
G
A
A
G
T
C
T
C
5900
G
C
T
G
C
T
T
T
C
A
G
A
G
C
C
A
G
G
C
T
T
C
T
C
T
C
C
T
G
C
T
G
C
C
A
C
C
C
C
C
A
C
T
G
C
T
C
T
T
C
5950
T
A
G
T
C
A
C
T
C
T
T
T
A
A
C
C
C
A
C
T
C
C
A
T
C
T
G
C
A
T
G
T
G
G
C
C
C
C
C
A
C
C
A
C
A
C
C
C
C
T
6000
C
A
A
A
G
T
G
G
T
C
A
A
G
G
T
T
G
T
C
C
T
G
T
T
G
C
T
T
A
A
T
T
C
C
A
T
G
G
A
A
G
C
T
T
G
G
C
T
A
T
6050
C
T
T
C
A
T
T
T
T
A
T
T
A
G
C
C
T
CTT TTGGCCTCTC ACCCTGTGAA AATCACTACA
6100
TTTTGTGCCA GAGATGGAGC TGGCATCTCC AGGCTTGGAA GAGGGCTGCT
6150
GAAGCTCAGC CAGGTGTCCT AAGGAGCCTC AGGACAGGGG ATGCTCAGTA
6200
GCCTTGCAAT GGGAACACAG CTGAGCCCCA CTTGGCCACC CTTTGCCACA
6250
ACCAGGCAGA AAGCAGCTTT TGAACAGATT TGTTGCCTCA GATTTGATCT
6300
CAAAGAAAAA TCGTGGGCAG TATTGGTCCC AGGTTCTGCT TTTTTACAAT
6350
TTCCTCTGAA ATCTGGATGC CTATCAACAC CTTGGAAAAA CTGAATTCTC
6400
CCCAACTAAT AGTGGTGTGT CACTGTAGTA AGCCTAGTAC AAAAATG
A
CC
6450 |
var(6448):[G:0.44]
TTCTTTGTGG AGGAGCTTCA TATCCTCCAT TTTTTTTTTG CTTAATTTTT
6500
GCCCAAGATG AGAACATAAT TTAGTTCACT TTTTATTTAT TCCCAACATC
6550
ATCCATGCAC CAACATTTTT GTAACTAAAG GAGGGACCAT TCAGAAGATG
6600
CTTATCAACT GTCAAAGTGA CAGTGTTACA ACCAATGCAC ATATTGTAAG
6650
AAATCAAACA ATGGCCTCCA AGGTTCATTT CTACACAGGG ATTAGCAGAT
6700
CAACATCAAT CTTGGCAACA CAGTTGCCAC TGATGGTGTC TTATTTTTTT
6750
TTAT
C
ATGAC ATGGCAATCA AGAGCAAACA TGATTTATTC TTATTTAAGA
6800 |
var(6755):[T:0.01]
TTTTATG
G
T
T
A
G
A
C
T
A
G
G
C
A
G
A
T
A
G
C
T
A
G
A
T
A
T
G
A
G
C
A
G
G
A
G
G
T
G
G
A
A
G
C
6850 |
REPEAT
C
C
C
T
G
A
G
A
G
A
A
T
G
G
A
G
G
T
C
T
G
G
A
G
A
A
T
C
T
G
A
A
A
C
C
C
C
A
G
A
G
A
T
T
A
C
C
C
A
A
6900 |
var(6867):[T:0.01]
G
T
C
C
T
G
C
A
T
G
C
T
A
G
A
C
A
T
G
A
G
T
G
G
A
G
G
A
G
G
G
G
G
A
A
T
A
C
C
T
A
G
G
T
A
G
A
A
A
A
6950
G
A
A
T
G
C
C
C
C
C
T
A
A
G
A
T
G
C
C
C
A
G
C
A
G
T
C
G
C
T
C
A
C
T
G
T
G
C
A
G
T
T
A
A
C
T
T
T
T
C
7000 |
var(6960):[T:0.48]
A
G
A
A
T
G
C
T
G
C
T
A
G
A
T
A
C
A
T
G
C
T
G
A
T
A
G
G
G
A
G
G
G
A
A
G
A
G
G
G
C
A
A
A
G
G
A
G
A
A
7050
A
T
T
C
C
T
A
A
G
A
G
A
T
A
C
A
C
G
G
T
T
G
C
A
G
T
T
A
G
T
A
T
A
C
A
T
C
T
G
A
G
T
G
C
T
A
T
A
C
A
7100
A
C
C
T
T
C
T
T
T
G
G
G
T
G
G
T
G
G
C
A
A
G
A
A
G
C
A
A
T
G
C
A
G
C
C
A
T
T
A
C
G
T
A
G
A
A
T
T
C
A
7150
T
A
T
C
A
A
A
C
A
C
C
TGTATCACA GGTGTTAAAG AAACAAGAAA CATTGTACTT
7200
CTTGTATTCT TAATAATGAT TTGCAATATT GTCTTTAGTA TCACTGCAAA
7250
CCTCTATAAA TATGATTTTT AAAAAGTATT TCTTTAGGTT GGAATTACTT
7300
CTACGCATTG ACTTATCTTC CTGGGTTTCA TTAGCCGTAC CCGTTGTACT
7350
TTCTTCCTTA CCACTGTTTA TCTCAAACTC TTGAGATTAA AGTAT
G
G
G
C
T
7400 |
REPEAT
C
A
G
G
A
G
G
G
A
G
C
G
A
G
G
A
G
C
T
T
C
A
G
G
A
C
T
C
T
C
A
C
G
G
A
C
C
T
C
C
A
G
C
A
C
A
G
T
G
T
7450
A
G
C
T
G
C
C
T
T
A
T
G
G
A
A
A
A
G
T
G
G
C
C
A
C
A
C
T
G
T
T
T
T
C
T
G
C
A
C
T
G
G
T
C
C
C
T
G
C
C
7500 |
var(7498):[T:0.01]
C
C
T
A
C
T
A
T
T
C
C
T
C
A
C
T
G
G
G
C
A
G
A
G
C
A
C
A
G
C
C
A
C
C
C
T
G
G
C
C
C
T
G
C
C
T
G
A
A
C
7550 |
var(7527):[A:0.08]
A
T
T
T
T
A
G
T
C
A
G
T
G
T
T
G
G
C
T
C
T
G
T
G
C
T
T
C
T
C
T
G
G
G
G
A
G
G
A
A
A
T
C
C
A
A
G
A
G
A
7600
C
A
A
C
C
C
A
C
A
G
C
C
C
C
T
C
T
G
C
C
A
T
T
T
C
A
G
C
T
G
C
A
G
C
A
G
T
A
C
C
A
C
C
G
T
T
A
A
T
G
7650
C
C
C
T
T
G
G
G
C
T
T
G
A
G
A
A
A
G
A
A
G
G
G
A
C
C
T
G
G
C
C
A
C
T
T
C
C
C
T
G
A
C
A
C
C
T
C
C
A
G
7700
C
A
C
A
C
A
G
C
A
G
G
G
A
A
A
G
A
A
T
T
C
C
A
G
T
T
T
C
T
C
T
T
T
C
T
T
G
T
G
A
G
C
T
T
T
C
A
C
C
T
7750
G
C
T
A
C
T
C
T
T
C
A
C
C
A
G
G
C
A
A
G
G
C
T
C
C
T
G
G
C
T
T
G
G
G
C
C
C
A
C
A
G
T
G
C
A
G
G
C
A
C
7800
C
T
C
G
A
A
C
T
C
A
G
T
T
G
A
A
C
A
T
T
T
C
C
A
C
T
G
G
C
T
G
C
A
C
T
C
T
G
T
G
T
T
T
T
T
G
T
G
G
G
7850
G
T
G
A
A
G
C
T
C
C
C
A
G
A
G
G
T
G
A
C
T
G
A
A
A
G
T
C
C
T
T
C
T
G
C
C
A
C
T
A
A
C
A
C
T
G
C
A
G
T
7900
C
A
T
A
C
T
G
C
C
C
T
T
G
C
T
G
T
A
C
T
T
G
G
A
C
T
A
G
G
G
A
A
G
G
A
A
A
A
A
A
G
A
T
C
C
T
G
A
G
T
7950
G
C
T
T
T
A
C
T
C
A
C
A
C
C
C
C
A
G
T
G
T
G
C
C
C
C
A
G
C
C
A
C
C
C
T
A
T
G
G
A
A
A
A
G
A
G
G
C
C
A
8000
G
T
G
T
G
T
C
A
T
C
C
C
TGCAAGCA CCCTGAGGCC CCTGCCCCTG CTGCCCCCAA
8050
GCTGTAGA
G
C
C
A
G
A
A
T
A
T
A
A
A
G
C
T
G
G
C
A
G
A
A
A
A
A
T
G
T
A
A
A
A
A
G
G
C
T
A
G
A
C
8100 |
REPEAT
T
G
G
C
T
T
A
G
C
C
T
C
C
C
A
G
C
C
T
A
C
A
T
C
T
T
T
C
T
C
C
T
G
T
G
C
T
G
G
A
T
C
C
T
T
C
C
T
G
C
8150 |
NOT SCANNED
T
C
T
T
G
A
A
C
A
T
C
G
G
A
C
T
C
C
A
A
G
T
T
C
T
T
C
A
G
C
T
G
T
G
G
G
A
C
T
T
G
G
A
C
T
G
T
C
T
T
8200
C
C
T
T
G
C
T
C
C
T
C
A
G
A
T
T
G
C
A
G
G
T
G
G
C
C
T
A
T
T
A
T
G
G
G
A
C
C
T
T
G
T
A
A
T
C
T
T
G
T
8250
G
A
G
T
T
A
A
T
A
C
C
A
C
T
T
A
A
T
A
A
G
C
T
C
C
C
C
T
T
T
G
T
G
T
G
A
G
T
A
T
A
T
C
T
A
T
A
T
C
T
8300
A
T
A
G
A
T
A
G
A
T
A
T
A
G
G
T
A
T
A
C
T
C
A
C
T
A
T
A
T
A
T
ACACATATA TACATATACT
8350
CTCTCTCTCT CT
C
T
C
T
C
A
T
A
T
A
T
A
T
A
T
A
T
A
T
A
T
A
A
T
C
T
C
C
T
A
T
T
A
G
T
T
C
T
8400 |
REPEAT
G
T
C
C
C
T
C
T
A
G
A
G
A
A
C
C
C
C
G
A
C
T
A
A
T
A
C
A
G
A
T
T
T
T
C
A
T
A
C
C
A
G
A
A
G
T
G
G
T
T
8450 |
REPEAT
C
T
T
G
A
G
G
A
A
C
A
G
A
A
T
A
T
T
A
A
G
G
A
T
G
G
A
A
T
T
C
T
T
T
C
A
T
T
G
G
T
T
T
T
G
G
G
A
C
T
8500 |
NOT SCANNED
T
C
T
G
G
T
G
T
T
G
G
C
T
G
A
T
T
A
A
T
A
T
G
A
T
T
A
G
A
C
C
A
A
A
A
A
A
T
G
C
T
A
A
G
G
A
C
T
C
T
8550
A
C
T
T
C
T
A
A
T
A
G
T
A
T
G
G
A
G
A
A
C
A
C
T
G
A
T
A
G
T
A
C
T
T
G
G
C
C
T
G
A
A
T
T
G
T
T
T
A
G
8600
A
G
A
G
T
T
A
T
G
C
A
A
A
A
T
A
A
A
T
G
C
A
T
T
T
G
A
C
A
C
T
A
C
T
G
A
T
T
C
A
T
C
A
C
T
T
A
T
G
A
8650
G
A
G
G
C
A
A
G
G
A
G
T
T
T
A
G
T
G
A
C
T
C
T
A
T
A
C
A
T
A
A
T
A
C
C
T
T
T
G
A
C
T
A
T
A
T
G
T
G
G
8700
A
G
A
A
C
C
A
A
G
G
A
A
C
A
T
A
A
T
G
A
A
G
T
T
G
G
T
T
G
A
T
T
G
C
T
C
C
T
A
A
G
T
T
C
T
C
T
G
G
A
8750
G
A
A
A
G
A
G
A
T
G
A
A
A
G
A
A
A
A
T
G
A
T
G
A
T
C
T
C
A
G
G
G
G
A
T
C
T
G
T
C
T
C
C
C
A
C
C
T
T
C
8800
A
G
A
A
G
C
A
G
A
T
A
C
T
G
A
G
C
C
A
C
A
A
A
T
C
T
G
C
T
A
A
G
A
T
T
G
C
C
C
T
G
A
A
T
G
A
G
A
G
T
8850
T
T
T
A
A
C
T
C
C
T
G
T
A
G
A
G
A
A
A
G
A
G
T
T
G
A
A
A
T
T
G
T
G
A
A
A
A
A
A
C
A
G
A
G
A
C
A
A
G
C
8900 |
var(8870):[A:0.03]
|
var(8894):[:0.02]
T
G
T
T
A
T
C
A
T
G
C
G
A
G
T
A
G
C
T
G
A
T
C
T
G
C
A
A
C
A
A
G
A
G
G
T
G
C
A
T
G
C
A
C
A
G
C
C
T
T
8950
G
C
C
A
G
G
T
G
T
T
T
A
C
T
G
T
T
A
A
A
G
T
G
A
G
G
G
C
A
T
T
G
A
C
T
G
G
A
A
A
A
A
A
A
T
G
G
G
A
C
9000
C
C
T
G
G
A
A
C
T
T
G
G
A
G
T
G
G
G
G
A
T
G
T
G
T
G
G
G
A
G
A
A
C
C
C
T
G
A
T
G
A
A
G
C
T
G
A
G
G
A
9050
C
A
C
T
G
A
G
T
T
T
G
T
G
A
A
C
T
C
T
G
A
T
G
A
A
A
C
T
T
T
T
T
T
G
C
C
A
G
A
A
G
A
A
A
C
A
G
T
T
T
9100
C
C
C
C
A
T
C
C
C
C
A
G
T
A
G
T
G
G
T
A
A
C
A
T
C
C
C
C
T
C
C
C
T
G
A
C
C
C
G
T
G
C
T
G
C
C
A
T
T
A
9150 |
var(9101):[T:0.11]
|
NOT SCANNED
G
C
C
T
T
T
C
C
A
C
C
T
T
T
G
T
C
T
G
A
G
G
A
T
G
T
A
A
A
C
C
C
T
G
C
A
C
T
G
C
T
T
G
A
G
G
C
A
A
C
9200
A
G
T
G
A
T
G
G
C
C
T
T
C
C
C
T
G
A
G
G
C
A
G
C
T
G
C
C
A
G
G
C
A
A
G
A
T
A
A
T
G
T
T
G
A
T
T
C
T
C
9250
C
T
C
A
A
G
A
G
G
C
A
C
C
C
C
T
A
A
T
G
C
C
C
C
T
G
A
A
T
G
C
T
T
C
T
A
G
A
C
C
T
A
T
A
A
C
T
A
G
G
9300
C
T
A
A
A
T
T
C
C
T
T
G
C
G
G
G
C
C
C
C
A
G
A
G
G
T
G
A
G
G
T
T
C
A
G
A
G
T
G
T
G
A
C
C
C
A
T
G
A
G
9350
G
A
G
G
T
G
C
A
T
T
A
T
A
C
T
C
T
A
A
A
A
G
A
A
C
T
G
C
T
T
A
A
G
C
T
T
T
C
T
A
A
T
T
T
A
T
A
T
T
G
9400
G
C
A
G
A
A
A
T
C
T
G
G
A
G
A
A
C
A
G
G
C
A
T
G
G
G
A
A
T
G
G
A
T
A
T
T
A
A
G
G
G
T
A
A
G
G
G
A
T
A
9450
A
T
G
G
T
G
G
A
A
G
G
G
A
C
A
T
A
G
A
G
T
T
G
G
A
T
C
A
A
G
C
T
G
A
A
T
T
T
A
T
T
G
G
T
T
T
G
G
C
C
9500
C
T
A
C
T
A
A
G
T
A
G
G
G
A
T
T
C
T
G
C
A
T
T
T
A
A
T
G
T
T
G
C
A
G
C
T
C
G
G
G
G
A
C
T
T
A
G
A
A
A
9550 |
var(9537):[T:0.01]
A
G
G
T
T
C
T
G
A
T
A
G
G
G
C
C
G
G
G
A
G
C
A
G
T
G
G
C
T
C
A
C
G
C
C
T
G
T
A
A
T
C
C
C
A
G
C
A
C
C
9600 |
REPEAT
T
T
G
G
G
A
G
G
C
G
G
G
G
G
C
G
G
G
C
A
G
A
T
C
A
C
G
A
G
A
T
C
A
G
G
A
G
A
T
T
G
A
G
A
C
A
A
T
T
C
9650
T
G
G
C
T
A
A
A
A
T
G
G
T
G
A
A
A
C
C
C
C
A
T
C
T
C
T
G
C
T
A
A
A
A
A
T
A
C
A
A
A
A
A
T
T
A
G
C
T
G
9700
G
G
C
A
T
G
G
T
G
A
T
G
C
G
T
A
A
C
T
G
T
A
A
T
C
T
C
A
T
C
T
A
C
T
T
G
G
G
A
G
G
C
T
G
A
G
G
C
A
A
9750
G
A
G
A
A
C
T
G
C
T
T
G
A
A
C
C
T
G
T
G
A
G
G
C
A
G
A
G
A
T
T
G
C
A
G
T
G
A
G
C
C
A
A
G
A
T
C
G
C
C
9800
C
C
A
C
T
G
C
A
T
T
C
C
A
G
C
C
T
G
G
T
A
A
C
A
G
A
G
C
A
A
G
A
C
T
C
C
A
T
T
T
C
C
A
A
A
A
A
A
A
A
9850
A
A
A
A
A
A
A
A
A
A
G
T
T
A
T
A
A
T
A
G
T
T
T
A
T
T
T
G
C
T
T
G
G
T
T
A
G
C
T
G
A
A
A
T
A
T
G
G
A
T
9900 |
REPEAT
T
A
A
A
A
G
A
T
G
G
T
C
C
A
A
T
G
T
T
A
G
T
G
A
G
C
T
G
G
A
A
A
T
G
C
C
T
T
G
G
T
T
T
A
A
T
G
T
A
G
9950
A
G
G
A
A
G
T
G
A
T
C
C
A
A
A
G
G
C
T
T
A
G
G
G
A
G
A
T
T
A
G
G
A
T
G
G
T
G
G
A
G
T
G
G
A
T
T
A
G
T
10000
C
A
C
T
T
T
A
G
A
C
C
T
A
C
T
C
A
T
C
C
C
A
G
C
T
G
G
G
A
G
G
G
T
C
C
A
G
A
A
G
A
T
A
C
A
C
C
C
T
T
10050
G
G
C
C
G
A
C
G
C
T
T
T
G
T
G
A
A
A
T
A
G
A
T
T
T
G
T
G
A
G
A
G
C
A
G
C
A
C
C
T
G
T
A
T
T
T
T
T
G
A
10100 |
var(10057):[A:0.15]
A
G
A
G
C
C
C
G
T
A
A
T
T
G
C
T
C
T
T
C
T
C
T
G
T
A
T
G
T
C
A
G
A
T
C
T
A
A
C
A
G
T
A
G
G
A
A
C
C
A
10150
C
A
G
T
C
A
C
T
C
A
A
C
T
A
C
A
A
A
A
T
T
T
A
A
A
T
A
C
A
A
T
G
G
G
A
A
T
A
A
T
T
G
G
A
T
C
C
T
G
A
10200
G
G
T
G
G
C
A
G
G
G
G
C
C
A
A
G
T
G
T
T
G
G
C
A
C
T
G
A
A
C
C
A
T
C
A
A
A
G
G
C
A
A
G
G
T
G
G
G
C
A
10250
T
A
A
C
T
A
C
C
A
T
A
A
T
A
G
A
C
A
G
C
A
G
A
G
G
C
A
A
A
G
C
A
G
C
C
A
T
C
A
G
A
A
T
A
G
T
C
T
G
A
10300 |
var(10270):[A:0.50]
C
T
C
A
T
G
T
A
G
A
G
C
T
C
T
G
G
C
A
T
T
G
G
C
T
A
A
T
T
A
A
T
C
A
T
G
G
T
G
T
T
C
C
T
A
G
A
A
G
T
10350
G
A
A
A
T
T
G
A
T
G
G
G
A
A
A
C
C
T
A
C
T
G
T
A
T
T
C
C
T
A
C
T
T
G
A
T
T
T
A
T
A
T
A
A
A
C
A
A
A
A
10400 |
NOT SCANNED
A
A
C
T
G
C
C
A
G
G
T
A
G
A
A
T
G
G
A
C
T
A
A
A
G
A
C
T
A
A
T
C
T
G
A
A
T
T
A
T
A
A
A
A
A
C
A
G
A
G
10450
A
A
T
C
A
T
G
G
G
C
C
C
T
C
A
A
T
C
A
A
T
T
T
C
C
A
G
A
C
T
C
G
A
A
C
C
T
G
T
T
A
C
A
G
T
T
C
C
A
G
10500
A
A
C
C
C
A
C
T
G
A
A
T
G
A
A
G
G
G
G
A
G
G
C
T
G
G
A
T
C
C
C
C
T
T
G
A
G
G
A
A
G
G
A
C
A
C
C
A
C
T
10550
A
G
G
C
T
A
C
T
G
A
C
A
A
C
T
T
A
T
G
C
T
G
T
T
A
C
T
C
T
T
T
C
T
C
C
C
A
T
C
C
T
T
C
C
C
T
A
A
G
G
10600
A
G
A
C
C
T
C
T
G
G
C
C
T
T
T
T
A
C
C
A
G
G
G
T
A
A
C
T
G
T
G
T
G
T
A
C
T
G
G
A
G
A
A
A
G
G
G
A
A
G
10650
T
A
A
T
G
A
G
A
C
A
T
T
T
C
A
G
A
A
A
G
T
A
C
T
G
G
A
C
A
C
T
G
G
C
T
C
T
G
A
G
C
T
G
A
C
G
T
T
G
A
10700
T
T
C
C
A
G
G
G
T
A
C
C
C
A
A
A
A
C
G
T
T
A
T
T
G
T
G
G
T
T
C
C
C
C
A
G
T
T
A
A
A
G
T
A
G
G
G
G
C
T
10750
T
A
T
G
G
A
G
G
T
T
A
G
G
T
A
A
T
T
A
A
T
G
G
A
G
T
T
T
T
A
G
C
T
C
A
T
T
T
C
T
G
A
C
T
T
A
C
A
G
T
10800
G
G
T
T
C
C
A
G
T
G
G
G
T
C
C
C
T
G
G
A
C
T
T
A
T
C
C
T
C
T
G
G
T
C
A
T
T
T
T
C
C
C
A
G
T
G
C
C
A
A
10850
A
A
T
G
C
A
T
A
A
T
T
T
G
T
A
T
A
G
A
C
A
T
A
C
T
T
A
T
T
A
G
C
T
G
G
C
A
G
A
A
A
T
G
C
C
A
C
A
T
T
10900
G
G
C
T
C
C
C
T
G
A
C
T
G
G
T
A
G
G
A
T
G
A
G
G
G
C
T
A
T
T
A
T
G
G
T
G
G
G
A
A
A
G
G
C
C
A
A
A
C
A
10950
G
A
A
G
C
C
A
T
T
A
G
A
G
C
T
G
T
C
T
C
T
A
C
C
T
A
G
A
A
A
A
A
T
A
A
A
A
A
A
A
T
C
A
A
A
A
A
C
A
A
11000
T
A
T
C
C
C
A
T
C
C
C
T
G
G
A
G
G
G
A
C
T
G
A
A
G
T
G
A
T
T
A
G
T
G
T
C
A
C
C
A
T
C
A
A
G
G
A
C
T
T
11050
G
A
A
A
G
A
C
G
C
A
G
G
G
G
T
G
G
T
G
A
T
T
C
C
C
A
C
C
A
C
A
T
C
C
C
T
G
T
T
C
A
A
C
T
C
T
C
C
C
A
11100
T
T
T
G
A
C
C
T
G
T
G
C
A
G
A
G
G
A
C
A
G
A
T
G
G
A
T
C
T
T
G
G
A
A
A
A
T
G
A
T
G
G
T
G
G
A
T
T
A
T
11150
T
T
T
A
A
G
C
T
T
A
A
C
C
A
A
G
T
G
G
T
G
A
C
T
C
C
A
A
T
T
G
C
A
G
C
T
G
C
T
C
T
A
C
C
A
G
T
T
G
T
11200
G
G
T
T
T
T
G
T
T
G
C
T
T
G
A
G
C
A
A
A
T
T
A
A
C
A
C
A
T
C
T
C
C
T
G
G
T
G
C
C
T
G
G
T
A
T
G
C
A
G
11250
C
C
A
T
T
G
G
C
T
T
G
G
C
A
A
G
T
G
G
C
T
T
T
T
T
C
T
C
C
A
T
T
C
C
T
G
T
C
C
A
T
A
A
G
A
C
C
C
A
C
11300
C
A
G
A
A
G
C
A
A
T
T
T
G
C
C
T
T
C
A
G
C
T
G
A
C
A
A
G
G
C
C
A
G
C
A
T
T
A
T
A
C
C
T
T
T
A
C
C
A
C
11350
C
C
T
A
C
C
T
C
A
G
G
G
G
T
G
T
A
T
C
A
A
C
T
C
T
C
C
A
G
C
T
T
T
G
T
G
T
C
A
T
A
A
T
C
T
T
A
T
T
T
11400
G
G
A
G
A
G
A
C
C
T
T
G
C
T
C
G
C
T
T
T
T
C
A
C
T
T
C
C
A
C
G
A
G
A
T
A
T
A
A
C
A
C
T
G
G
T
C
C
A
T
11450
T
A
C
A
T
T
C
A
T
G
A
C
A
T
T
A
T
G
A
T
G
A
T
T
G
G
A
T
A
C
A
G
T
G
A
G
C
A
A
G
A
A
G
T
A
G
C
A
A
A
11500
C
A
C
A
C
T
G
A
A
C
T
T
A
T
T
G
G
T
G
A
G
A
C
A
T
T
T
G
T
A
T
G
C
C
A
G
A
G
G
A
T
G
G
G
A
A
A
T
A
A
11550
A
T
C
C
A
G
C
T
A
A
A
A
T
T
T
A
G
G
G
A
C
T
T
T
C
T
A
C
C
T
C
G
G
T
A
A
A
A
T
T
T
C
T
A
G
G
G
T
T
C
11600
C
A
G
T
G
G
C
A
T
G
A
G
A
C
C
T
A
T
G
G
A
G
A
T
A
T
T
C
C
T
T
C
T
A
A
G
G
T
G
A
A
G
C
A
T
A
A
C
T
T
11650
G
C
T
G
C
G
T
T
T
G
G
C
C
C
C
T
C
T
T
A
C
A
A
C
C
A
A
G
A
A
A
G
A
G
G
C
A
C
A
A
T
G
C
C
T
G
G
T
G
G
11700
G
C
C
T
A
T
T
T
G
G
A
T
T
T
T
G
G
A
G
G
C
A
A
C
A
C
A
T
T
C
C
T
C
G
T
T
T
G
G
G
T
G
T
G
T
T
A
C
T
C
11750
T
G
G
C
C
C
A
T
T
T
A
T
C
G
A
G
T
G
A
C
C
T
G
A
A
A
G
G
C
T
G
C
C
A
G
A
T
T
T
A
A
G
T
G
C
A
G
T
C
T
11800
A
G
A
A
C
A
A
A
A
G
A
A
G
G
C
T
C
T
G
A
A
A
C
A
G
G
T
C
C
A
G
G
C
T
G
C
T
G
T
G
A
A
A
G
C
T
G
C
T
C
11850
T
G
C
C
A
T
T
T
G
G
G
C
C
A
C
A
T
G
A
C
C
C
C
G
C
A
G
A
T
C
C
A
A
T
G
G
T
G
C
T
T
G
A
G
G
T
G
T
C
A
11900
G
T
G
G
C
A
G
A
T
A
G
G
G
A
T
G
C
T
G
T
T
T
G
G
A
G
C
C
T
T
T
G
G
C
A
G
G
C
C
C
C
C
A
T
A
G
G
T
G
A
11950
A
T
C
A
C
A
G
T
G
G
A
G
A
C
C
T
C
T
A
G
G
A
T
T
T
T
G
G
A
G
C
A
A
G
G
C
C
C
T
G
C
C
A
C
T
T
C
T
G
C
12000
A
G
A
T
A
A
C
T
A
C
T
C
T
C
C
T
T
T
T
G
A
G
A
G
A
C
A
G
C
T
A
T
T
G
G
T
C
T
G
T
T
A
T
T
G
G
G
C
T
T
12050
T
G
G
T
G
G
T
A
A
C
T
G
A
A
C
G
T
T
T
G
A
C
T
G
T
G
G
G
T
C
A
T
A
A
A
G
T
C
A
C
C
A
T
G
C
T
A
C
C
T
12100
G
A
A
C
C
T
G
C
C
T
A
T
C
A
T
G
A
A
C
T
G
G
T
T
G
C
T
T
T
C
T
G
A
C
C
C
A
T
C
T
A
G
C
C
A
T
G
A
A
G
12150
T
G
G
G
T
C
A
G
C
A
C
A
G
C
G
G
C
A
T
T
T
C
A
T
C
A
T
C
A
A
A
T
T
G
A
A
G
T
G
G
T
G
T
G
T
A
T
G
T
G
12200
A
T
C
G
G
G
C
T
T
G
A
G
C
A
G
G
T
C
C
T
G
A
A
G
G
C
A
C
A
A
G
T
A
A
G
T
T
A
C
A
T
A
A
G
G
A
A
G
T
G
12250
G
C
T
C
A
A
A
T
G
C
C
C
A
T
G
T
T
C
T
C
C
A
C
T
C
A
T
G
C
C
A
C
C
C
T
G
C
C
T
T
C
C
C
T
C
C
C
C
C
A
12300
G
C
C
T
G
C
A
C
C
A
A
T
G
G
C
C
T
C
A
T
G
G
G
G
A
G
T
T
C
C
C
T
A
T
G
A
T
C
A
G
T
T
G
A
C
A
G
A
G
G
12350
A
A
G
G
G
A
A
G
A
C
T
A
A
G
G
A
C
T
G
G
T
T
C
A
T
A
G
A
T
G
G
T
T
C
T
G
C
A
C
G
A
T
A
T
G
C
A
G
G
C
12400
A
C
C
A
C
C
C
G
A
A
A
G
T
G
G
A
C
A
G
C
T
G
C
A
G
C
A
C
T
A
T
A
T
C
C
A
C
T
T
T
C
T
A
AA
T
G
C
A
T
12450 |
REPEAT
G
T
G
T
A
C
A
C
T
T
G
T
G
C
T
A
A
G
A
A
A
A
T
A
T
C
T
T
T
A
T
T
T
T
A
T
T
T
C
C
T
T
T
A
T
T
T
T
T
C
12500
C
T
T
T
A
T
C
A
T
G
T
G
A
C
C
T
T
A
G
A
T
T
T
A
T
G
G
A
C
T
T
C
A
C
A
T
C
A
G
C
A
T
T
T
A
A
G
C
A
T
12550
T
T
A
A
G
T
G
T
T
G
T
T
C
A
T
A
T
C
A
G
C
A
T
T
T
A
A
A
T
A
T
T
G
T
T
A
A
C
C
T
T
A
T
G
T
A
A
T
A
A
12600 |
var(12566):[G:0.02]
C
T
T
T
T
G
G
T
T
T
G
G
G
G
A
T
T
G
G
T
G
C
G
T
T
T
C
T
G
G
T
T
G
T
A
T
G
A
G
G
A
T
A
G
T
T
G
T
A
T
12650
T
A
T
A
T
T
A
G
G
C
A
T
A
A
T
T
A
T
G
A
C
C
T
T
A
T
T
A
T
T
G
T
C
T
T
T
A
T
T
T
G
A
A
G
A
T
T
A
T
G
12700
T
A
T
G
A
T
T
T
C
A
G
G
A
T
G
T
G
T
G
T
A
T
G
G
G
T
T
C
A
A
G
T
T
G
A
C
A
A
G
G
A
G
T
T
G
G
A
C
T
T
12750 |
var(12742):[C:0.11]
|
REPEAT
G
T
G
A
T
G
G
T
T
A
A
T
A
C
T
G
T
C
A
A
C
T
T
G
A
T
T
G
G
A
T
T
G
A
A
A
G
A
T
G
C
A
A
A
G
T
A
T
T
A
12800
A
T
C
T
C
G
G
T
T
A
T
G
T
C
T
G
T
G
A
G
G
G
T
G
T
G
G
C
A
A
A
A
G
G
A
G
A
T
T
A
A
C
A
T
T
T
G
A
G
T
12850
C
A
G
T
G
G
G
C
T
G
G
G
A
A
G
G
C
A
G
A
C
C
C
A
C
C
C
T
T
A
A
T
C
T
G
G
G
T
A
C
A
C
A
C
C
A
T
C
T
A
12900
A
T
C
A
A
G
T
T
C
C
A
G
T
G
T
G
G
C
C
A
G
A
T
T
G
T
A
A
A
G
C
A
G
G
G
A
G
A
A
A
A
A
T
G
T
G
A
A
A
A
12950
G
A
C
T
A
G
A
C
T
G
A
A
T
T
A
G
C
T
T
C
C
C
A
G
C
C
T
A
C
A
T
C
T
T
T
C
T
C
C
T
G
T
G
C
C
A
A
A
T
G
13000
C
T
T
C
C
T
G
C
T
C
T
T
G
A
A
C
A
T
C
G
G
A
C
T
C
C
A
A
G
T
T
C
T
T
C
A
G
C
G
T
T
G
G
G
A
G
T
T
G
G
13050
A
C
T
G
G
C
T
T
T
C
T
T
G
C
T
C
C
T
C
A
G
C
T
T
G
C
A
G
A
G
G
G
C
C
T
G
T
T
G
T
G
G
A
A
C
C
T
T
G
T
13100 |
NOT SCANNED
G
A
T
C
C
G
C
T
G
A
G
T
T
A
A
T
A
C
T
A
C
T
T
A
A
T
A
A
G
A
T
C
C
C
C
T
T
T
A
T
A
T
A
C
A
T
A
T
A
A
13150
T
A
T
A
T
T
A
T
A
T
T
A
T
A
T
A
T
A
A
T
A
T
A
T
A
T
A
A
T
A
T
A
T
A
T
T
A
T
A
T
A
T
A
A
T
A
T
A
T
A
13200
T
A
A
T
A
T
A
T
T
A
T
A
T
A
T
T
A
T
A
T
A
T
A
A
T
A
T
A
T
A
T
T
A
T
A
T
A
T
T
A
T
A
T
A
T
A
A
T
A
T
13250
A
T
A
T
T
A
T
A
T
A
T
A
A
T
A
T
A
T
A
T
T
A
T
A
T
A
T
T
A
T
A
T
A
T
T
A
T
A
T
A
T
A
A
T
A
T
A
T
A
T
13300
T
A
T
A
T
A
T
A
A
T
A
T
A
T
A
T
A
A
A
A
T
A
T
A
T
A
T
A
T
A
T
C
C
T
A
T
T
A
G
T
T
C
T
G
T
C
C
C
T
C
13350 |
REPEAT
T
A
G
A
G
A
A
C
C
C
T
G
A
C
T
A
A
T
A
C
A
A
T
T
T
A
T
G
T
C
A
T
T
A
A
T
C
T
C
A
T
T
T
A
T
T
G
A
T
T
13400 |
REPEAT
T
G
T
A
T
A
C
A
T
T
G
A
A
C
C
A
A
C
C
T
T
A
T
A
T
C
C
C
A
G
G
A
A
T
A
A
A
A
C
C
T
A
C
T
T
G
A
T
T
G
13450
T
G
G
T
G
G
A
T
T
A
G
C
T
T
T
T
T
G
A
T
G
T
A
C
T
C
T
T
G
G
A
T
T
C
A
A
T
T
G
C
T
G
G
T
A
T
T
T
T
A
13500
T
T
G
A
G
A
A
T
T
T
T
T
G
C
A
T
C
T
G
T
G
T
T
C
A
T
C
A
A
G
G
A
T
A
T
T
G
G
C
T
T
G
A
A
G
T
T
T
T
C
13550
T
T
T
T
T
T
T
G
T
T
G
T
T
C
C
A
T
A
T
C
A
G
A
A
T
G
A
T
G
A
C
G
A
C
C
T
C
A
T
A
G
A
A
T
G
A
G
T
T
A
13600
G
T
C
T
G
T
C
C
T
C
T
T
T
T
A
T
C
T
T
T
T
G
G
A
A
T
T
G
T
T
T
C
A
G
G
A
G
G
C
T
T
G
A
T
A
T
C
A
G
C
13650
T
C
T
T
C
T
T
T
A
T
A
T
G
A
C
T
G
G
T
A
T
A
C
T
T
T
G
G
C
T
A
G
G
A
A
T
C
T
C
T
C
T
G
G
T
C
C
A
G
G
13700
G
G
T
T
T
T
T
C
T
G
G
T
G
T
A
G
G
T
T
T
T
T
A
A
T
T
A
C
T
G
A
T
T
C
A
A
C
T
T
C
A
G
A
A
C
T
C
A
T
T
13750
A
C
T
C
A
T
T
A
T
T
G
A
G
T
T
C
T
A
A
A
A
C
T
C
A
C
T
T
T
C
A
T
G
T
A
C
T
C
T
T
C
A
A
A
A
G
A
C
T
G
13800 |
REPEAT
T
C
T
T
C
T
T
C
T
G
T
T
G
T
T
G
A
G
C
G
G
G
G
T
G
T
T
C
T
C
T
C
A
A
G
G
T
C
G
T
T
T
A
G
G
T
G
A
A
G
13850
G
T
G
G
T
T
G
C
T
G
G
T
G
T
T
C
T
T
C
T
G
T
A
T
C
C
T
T
A
C
T
G
C
T
T
G
T
C
T
T
T
C
T
C
T
T
T
T
T
T
13900
T
A
T
T
G
A
C
T
A
C
T
G
A
G
G
A
T
T
A
A
T
G
G
T
G
A
T
G
T
G
T
C
C
A
A
C
T
T
T
A
A
C
T
C
T
A
G
A
T
T
13950
A
G
T
C
T
A
T
T
T
C
T
C
T
T
T
T
A
G
A
T
T
G
T
A
A
C
T
C
T
G
T
T
T
T
A
T
A
T
A
T
T
T
T
G
A
A
G
C
T
C
14000
T
G
T
T
G
T
T
A
G
G
C
A
T
G
T
G
T
A
T
T
T
G
G
A
T
T
G
T
T
A
G
G
T
C
T
T
C
T
T
G
A
T
G
A
T
G
A
C
C
T
14050
T
T
A
T
C
A
T
T
A
T
G
T
A
A
T
G
T
T
T
C
T
T
C
T
T
A
T
C
T
C
T
G
G
A
A
G
T
A
T
T
C
G
T
T
G
T
T
C
T
G
14100
A
A
G
T
C
T
A
T
T
T
G
T
G
C
T
G
A
T
A
T
G
A
A
T
A
C
A
G
C
C
T
T
C
A
C
A
G
C
T
C
T
A
T
T
T
T
C
A
C
T
14150
A
G
T
A
T
T
T
G
T
A
T
A
T
C
T
T
T
T
T
C
T
C
A
G
C
T
T
T
T
A
A
A
T
T
G
A
G
A
T
G
T
T
C
A
G
A
C
C
A
T
14200
T
T
G
C
A
T
T
A
A
A
G
T
A
G
T
T
G
T
T
A
A
T
A
G
G
A
T
T
A
A
A
T
T
T
A
A
A
T
C
T
A
C
C
A
T
T
A
A
G
T
14250
T
G
G
T
T
A
T
T
T
C
T
C
T
T
T
G
T
C
C
C
A
T
T
T
A
A
A
C
T
T
T
G
T
T
C
C
T
T
T
T
T
T
C
A
T
A
T
T
T
T
14300
T
C
T
G
C
C
T
T
C
A
T
T
T
A
T
A
T
T
G
A
G
T
T
T
A
T
C
T
C
C
A
C
G
A
C
T
T
A
C
T
T
A
T
T
A
A
A
T
T
A
14350
A
T
T
T
T
T
A
A
T
G
G
T
T
T
T
A
G
T
A
T
T
T
T
C
C
A
C
A
A
T
G
T
T
T
A
T
A
A
T
A
T
A
T
A
C
T
T
T
G
A
14400
T
T
T
T
T
T
C
A
C
A
T
T
C
C
A
C
C
T
T
C
A
A
A
T
G
A
C
A
G
A
A
T
T
A
T
A
C
T
G
G
A
T
A
T
A
T
A
G
A
A
14450
A
T
C
T
T
A
C
A
T
C
A
T
T
G
C
A
C
T
T
C
T
C
C
T
T
C
C
T
C
C
C
T
C
T
C
A
A
A
A
T
G
T
T
G
T
G
C
T
A
T
14500
T
G
C
T
C
T
T
T
G
T
A
A
T
A
G
A
G
G
C
T
T
A
C
T
T
C
T
A
T
T
A
T
G
T
T
A
T
A
G
C
T
C
T
C
A
T
A
A
T
A
14550
C
A
T
T
G
A
C
A
C
T
A
T
T
T
T
T
A
C
C
C
T
G
A
A
T
A
A
T
C
A
G
T
T
G
T
T
T
T
T
T
A
A
A
G
T
G
A
T
T
A
14600
T
G
A
C
T
A
C
A
A
A
T
A
T
T
T
T
G
A
A
T
A
A
T
T
T
C
T
T
T
A
T
T
T
T
A
C
C
A
T
T
T
C
T
G
G
T
G
C
T
C
14650
C
T
T
A
T
C
T
T
T
T
A
C
A
G
T
A
G
A
T
C
C
C
A
A
T
T
T
C
C
A
T
C
T
G
G
A
G
T
C
A
C
A
T
T
C
T
T
T
C
T
14700
G
T
G
A
A
A
A
A
C
A
A
C
C
T
T
T
A
G
C
A
T
T
T
C
T
T
A
T
A
G
C
A
C
G
G
G
A
C
T
G
C
T
G
T
T
G
C
T
G
T
14750
T
G
T
C
T
T
T
C
A
G
C
T
T
T
T
C
T
T
T
G
T
C
T
G
A
A
G
A
A
G
T
C
T
T
T
A
T
T
T
T
G
C
C
T
T
C
A
G
T
T
14800
T
T
T
A
A
A
A
G
T
G
A
T
T
T
T
G
C
T
G
A
G
T
A
T
A
G
A
T
A
C
T
G
G
G
T
T
G
A
G
A
G
T
T
T
C
A
T
T
C
C
14850
T
T
G
T
A
T
C
A
T
T
T
T
A
A
C
A
A
T
G
A
T
G
T
T
C
C
A
T
T
A
T
A
T
T
C
C
G
T
T
T
T
G
A
A
T
A
G
T
T
T
14900
C
T
G
A
C
T
A
G
A
A
A
T
C
T
G
A
T
C
T
T
T
G
T
T
T
C
T
T
T
G
T
A
T
T
C
A
A
T
A
G
T
T
C
C
T
T
T
T
T
C
14950
T
C
T
G
A
C
T
G
C
C
T
T
T
A
A
G
A
T
A
T
T
C
T
C
A
T
C
T
T
T
G
T
T
T
T
T
C
A
A
C
A
G
T
T
T
G
A
C
T
A
15000
T
A
A
T
T
T
G
T
T
T
A
T
T
A
T
T
A
A
C
T
T
T
T
T
G
T
A
T
T
T
A
T
T
C
T
G
C
T
T
G
A
G
G
T
T
T
C
C
T
G
15050
A
G
C
T
C
C
T
T
G
G
A
T
T
T
G
C
A
G
A
T
T
G
T
T
G
A
T
T
T
T
T
A
T
T
G
T
T
T
T
T
G
T
A
A
A
A
T
T
C
A
15100
T
A
G
C
C
A
T
T
A
T
C
T
A
T
T
C
T
A
C
T
G
T
T
T
T
G
T
T
T
T
T
T
T
T
T
T
C
A
C
T
T
C
T
C
T
C
T
C
T
C
15150
T
G
T
A
T
T
C
T
T
C
T
T
T
T
T
G
G
A
C
T
G
T
A
A
G
T
A
T
T
C
A
A
A
T
G
T
T
A
G
A
T
C
A
T
T
C
A
T
A
T
15200
T
G
C
T
T
C
A
T
A
A
A
C
C
T
T
A
T
A
T
G
C
T
T
C
T
T
C
T
G
C
T
T
T
T
T
T
T
T
T
T
T
T
G
T
C
A
G
G
A
A
15250
C
T
C
T
T
T
T
T
T
T
G
T
A
T
C
T
G
T
G
T
T
G
G
T
T
T
G
G
A
T
A
A
G
T
T
C
T
A
G
T
A
G
A
C
T
A
T
G
T
T
15300
C
A
A
G
T
T
T
A
T
G
G
A
T
T
A
T
T
T
T
G
T
T
A
G
T
T
G
T
G
T
C
T
A
A
T
T
G
A
C
T
C
C
T
C
A
G
T
G
C
A
15350
T
T
C
A
G
A
G
A
A
T
T
C
T
T
C
A
T
C
T
C
T
G
A
T
A
T
T
A
T
A
A
A
T
C
T
C
T
T
C
C
T
A
G
C
A
T
T
T
T
C
15400
A
T
G
T
T
A
C
T
C
T
T
T
T
C
T
A
T
A
G
T
T
T
C
C
A
T
C
T
C
T
T
T
G
C
T
G
A
A
A
T
T
C
T
C
C
C
C
C
T
A
15450
T
C
C
A
T
G
G
A
T
A
T
T
G
T
C
C
A
C
C
T
T
T
A
C
C
A
C
A
A
G
A
T
T
C
T
T
T
A
A
C
A
T
A
T
T
A
A
C
A
T
15500
A
G
G
T
A
T
C
A
T
A
C
A
A
A
C
C
C
A
A
A
C
T
G
A
T
A
G
T
T
T
C
C
A
G
A
T
G
G
T
G
T
C
T
T
T
T
C
T
G
A
15550
G
T
C
T
G
T
C
T
G
T
C
T
T
G
A
T
T
G
C
T
T
T
A
T
T
A
T
T
T
A
A
C
A
G
T
G
A
C
T
T
A
T
C
T
T
C
C
C
T
C
15600
T
T
C
A
G
C
T
T
T
T
G
G
T
G
T
G
T
C
T
T
G
T
A
A
T
T
G
T
T
T
A
A
T
C
A
A
A
C
A
C
T
G
G
G
T
A
T
C
A
T
15650
A
A
A
T
G
G
A
G
G
A
A
C
A
G
T
A
G
A
G
A
T
T
G
C
A
G
T
A
A
A
T
A
T
T
A
T
T
T
A
T
G
C
T
T
T
G
A
A
A
T
15700
G
G
G
C
A
C
C
C
A
T
C
T
T
C
T
G
T
T
G
A
A
A
A
T
A
T
G
T
T
T
T
G
T
G
G
T
C
A
A
T
T
G
A
G
T
C
A
A
C
C
15750
T
A
G
T
A
A
C
T
G
G
T
T
G
A
A
C
T
G
A
A
T
T
T
G
G
C
A
T
T
T
G
T
G
C
T
T
G
T
T
G
C
T
T
T
T
A
T
C
T
T
15800
A
A
A
T
G
C
A
C
C
A
C
A
G
G
T
T
T
A
A
A
T
T
C
C
T
C
C
A
G
T
G
A
T
G
G
G
T
T
G
C
T
G
C
T
A
T
C
T
T
T
15850 |
var(15845):[G:0.01]
T
G
C
T
T
A
G
A
G
T
G
G
G
G
C
C
T
G
G
G
G
T
G
T
G
G
A
A
G
A
A
T
T
T
T
C
T
C
A
G
T
G
T
T
C
C
T
A
T
C
15900
T
A
T
T
A
T
T
A
G
A
T
T
T
T
A
G
C
A
G
T
C
A
C
T
G
C
A
T
G
C
C
T
G
C
A
C
T
A
C
A
G
A
G
G
G
G
A
T
A
T
15950
C
T
T
C
A
T
A
C
A
T
A
T
A
A
T
C
T
A
A
C
C
C
C
A
T
T
G
A
A
A
C
T
G
C
T
G
T
T
T
C
T
T
C
T
T
A
A
T
G
A
16000 |
var(15960):[C:0.49]
A
T
G
C
T
C
A
A
T
C
T
T
T
G
G
T
G
G
A
A
A
T
A
A
A
C
A
A
A
T
G
C
T
G
T
A
T
C
T
C
C
T
G
G
A
G
C
C
A
C
16050
T
T
C
A
G
T
C
T
T
A
G
T
C
A
G
G
T
T
C
T
G
C
A
G
G
G
C
T
T
T
G
A
A
G
G
G
A
A
T
G
C
A
T
T
C
T
C
A
G
T
16100
A
T
T
C
T
T
G
T
G
C
C
T
T
A
T
T
T
G
G
A
T
G
G
A
A
C
T
T
G
A
A
C
C
T
G
T
G
G
T
G
G
G
T
T
T
G
G
A
G
A
16150
G
A
A
A
G
A
G
T
A
G
C
A
G
A
C
G
T
C
T
G
C
T
A
T
G
T
T
G
C
A
A
T
G
C
A
G
G
A
T
G
C
T
G
G
G
C
A
C
A
A
16200 |
var(16165):[T:0.01]
G
A
A
A
A
T
T
T
C
C
A
G
T
C
T
C
T
C
C
T
C
C
A
A
G
G
A
A
A
T
A
A
G
A
T
T
T
GAT CATCTACCTA
16250
TCCCTGAGAA GTGAAGGGCT TTGCCTGCGG TGCTAGATGC AAAACCATTT
16300
TTCTCCCC
C
C ATTG
C
C
C
A
G
A
A
A
C
T
T
A
A
G
G
C
T
T
T
G
G
C
T
T
T
T
C
T
G
A
G
C
A
G
T
G
16350 |
var(16309):[T:0.04]
|
REPEAT
G
T
C
T
A
G
G
G
A
A
T
T
G
T
G
C
A
A
G
G
T
T
T
T
C
A
T
A
T
T
T
G
A
C
C
C
T
G
A
C
A
G
C
C
C
A
T
C
A
C
16400
C
A
C
C
T
A
C
A
G
C
T
T
G
C
A
G
T
G
C
C
A
A
A
T
G
T
A
T
C
T
C
C
C
T
C
T
G
A
T
C
T
C
T
C
C
T
G
T
C
C
16450
T
G
T
G
G
T
C
C
T
C
A
T
G
A
A
C
A
T
T
A
A
G
A
A
G
A
G
A
T
T
T
C
T
A
A
A
A
A
A
G
A
G
C
T
T
G
C
A
C
A
16500
T
G
A
G
CATAGT TTCTGGTGAG AAGAATTCTG ATATGTTAAC TTCCTCTAAA
16550
CTTTTAAATA AAATATTTCT AAGAATTAAA TAAAGTTCTA GAATGATATG
16600
AATCTATTCC TTTGGTTTTT TGCACGTCTG TCTGCCTGCT AATCAAGAGA
16650
AGAGAATGGT CGTAATTCTC AGAGACTTTT TCCTGTTTGT GTCATAAATG
16700
ACTTCACATT TTTTTCTGTT CTAAGAACTA TTCAGCTTGA TTTCTTCTGT
16750
TTTAATTTTA G
C
A
G
C
A
C
C
T
G
A
G
C
A
A
A
G
C
C
A
T
G
T
G
G
T
C
C
A
G
G
A
T
T
G
C
T
A
C
C
16800 | Exon 3
A A P E Q S H V V Q D C Y 29
A
T
G
G
T
G
A
T
G
G
A
C
A
G
A
G
T
T
A
T
C
G
A
G
G
C
A
C
G
T
A
C
T
C
C
A
C
C
A
C
T
G
T
C
A
C
A
G
G
A
16850
H G D G Q S Y R G T Y S T T V T G 46
A
G
G
A
C
C
T
G
C
C
A
A
G
C
T
T
G
G
T
C
A
T
C
T
A
T
G
A
C
A
C
C
A
C
A
T
C
A
A
C
A
T
A
A
T
A
G
G
A
C
16900
R T C Q A W S S M T P H Q H N R T 63
C
A
C
A
G
A
A
A
A
C
T
A
C
C
C
A
A
A
T
G
C
GTATGTCAT TAAT
C
TTACA GTAAGCAAAA
16950 |
var(16935):[T:0.01]
T E N Y P N A 70
CAAGGTCCAA GTAAAATTTG TCTTAGAAAA GGTGTGCGTC AAGCTAACTT
17000
CTTATGATTA AATTTTTCTC ACACATAGAA TGCATGGCAA AATGTCTGAG
17050
AAACATTACT TTGAGCAAAG AGTATGAT
T
G AAGAGAAATG TTAAGCTGGC
17100 |
var(17079):[A:0.47]
TCTCTTTCCT GAGAGTTTGA TAAAATCAGG AGAATATCTG GCGGTGGTGA
17150
GGCCACAATA ATGGAAAATC AGAATGTTTA GACAGAGTCA GCTTCAACAA
17200
CACTCACTAA AGGTCAATGT GATCTTTACC CCTTGAAATT CTATAATTCT
17250
AATCTCCAAT TCCTGAAGTG AAGGTTGTGT TGGCCTTTTC TGTCTTGGC
T
17300 |
NOT SCANNED
C
A
C
A
A
G
T
A
A
A
T
G
A
T
A
T
G
T
G
C
A
T
A
T
C
T
A
T
G
G
A
A
A
G
G
C
G
A
A
T
C
T
A
T
C
T
T
T
T
T
17350
C
T
A
T
A
T
C
T
A
T
G
T
C
T
A
T
T
C
C
A
A
C
G
G
G
T
A
G
A
A
A
C
A
C
C
C
T
G
G
G
T
C
C
T
G
A
G
C
A
C
17400
C
A
G
T
G
G
T
C
T
G
A
A
G
G
A
A
T
A
C
G
G
G
T
T
G
C
C
A
G
G
A
A
G
A
G
A
G
A
AG CAAAGGCAGG
17450
AAGGCAGATG AAAGTAAGAA ATGAGACAGA TGCTAAACAA TAAAAAGTGC
17500
GGGAAGATAG ACAGAAGCTG GGGTCTGACC ACACCATGGC CAGTCTTTCA
17550
CACATAAGTG ACT
A
C
C
A
A
A
G
A
C
A
A
G
A
A
A
A
A
A
T
G
A
T
T
T
C
C
G
C
T
T
G
T
T
G
G
A
C
17600 |
REPEAT
A
A
T
A
G
A
T
G
G
T
A
G
A
G
G
A
C
C
A
A
G
G
G
A
A
T
T
G
C
G
A
G
A
G
A
G
A
G
A
A
C
A
A
T
G
A
G
A
T
C
17650 |
var(17638):[T:0.02]
A
A
C
T
C
A
A
C
A
G
A
T
G
C
A
C
T
G
G
T
T
T
T
C
T
T
C
C
T
G
G
A
G
A
C
C
C
T
T
C
C
T
G
C
A
C
T
G
A
A
17700
G
G
G
C
A
G
G
A
G
A
T
G
G
A
G
C
C
C
A
A
A
A
A
A
A
A
C
T
G
T
A
G
C
C
A
T
C
T
T
G
C
T
G
A
A
C
A
G
A
G
17750
G
A
G
G
G
A
C
A
T
T
G
G
A
G
T
T
T
G
G
G
A
T
T
A
T
T
C
A
G
G
T
G
G
C
T
A
G
G
A
T
T
T
T
C
T
A
G
G
C
C
17800 |
var(17762):[A:0.10]
T
G
C
T
A
A
C
A
A
T
G
A
G
A
A
C
A
G
A
T
T
T
G
T
G
G
A
G
G
A
A
A
G
G
A
G
T
T
C
T
A
G
A
A
A
T
A
T
G
C
17850 |
var(17836):[A:0.10]
A
T
A
G
A
A
A
T
C
T
C
C
T
C
G
A
G
T
C
A
T
T
G
G
C
T
A
A
A
C
A
T
G
A
A
G
C
T
G
C
A
T
G
T
A
C
A
C
A
G
17900
A
A
A
A
T
A
G
A
T
C
C
A
C
A
A
G
A
A
A
G
T
A
G
G
G
C
A
A
A
G
A
A
C
A
T
C
T
A
C
G
G
A
A
G
A
G
C
A
G
C
17950
A
A
C
T
A
C
A
A
T
G
G
A
A
C
A
G
T
G
AG CTCAATAAAC ATGACAGAGC TCAAATAGCA
18000
CTAAGGGATA TTGGAGTTTG GACCACACAG AGGAGAGAGA CTTCACTGAA
18050
CATCTTGGGC ATTCAGTAGA GACCCAGGAA AAGCCATACT TTAGGAGTAG
18100
AATTAGTATA TTCTTAGAAT AAAGGCAGCT CCACACAAAC AATAGCAAAA
18150
CTGAAAAGGA AGTCTCCAAG CATCAGAATG ATGTCCAAGT CAATGAACTG
18200
CCTCTGAGAG GAAAACTCAA CCATCTTTAG AGGTAAACAT CAAAGTCAAG
18250
TGGCTCAGCT ATGCAGTATC CA
C
AGTGTGA GGCCTAAATA TAAAACTTGA
18300 |
var(18273):[T:0.03]
CTACACATAG AAACCTTT
T
A
G
T
G
T
G
A
C
C
C
A
C
A
A
G
C
A
G
G
A
G
G
A
A
A
A
T
C
A
G
T
18350 |
REPEAT
|
var(18339):[G:0.49]
|
var(18350):[T:0.50]
C
A
A
T
A
C
A
A
A
C
A
G
A
C
C
C
A
G
A
A
G
A
G
A
C
A
G
A
A
A
T
G
A
T
T
A
G
A
A
T
GGCATAAAAA
18400 |
var(18390):[G:0.10]
TTTGACATAT CACTATATAA TAATTGAGTT CTAGGATTTA AGAAAACATG
18450
AATATAGAAT GCAACAGACA CCTTATCCAG AGACAGTAAG AGTATAAAGA
18500
GCCAAATCGA AGAACTACTA AGAGATATGT CTTAAATGAA AAAATTACTA
18550
GATGGCCTCC CCATCTAGTT AGACATTTCA GAAGAAAATA CCAAATGAAA
18600
AATAATTGCA TAGAACCTAC AGAACCAGAT ACACACA
T
AC AAAACACACG
18650 |
var(18638):[A:0.11]
CATGCATACA CACACACTCA AACATGTATA AGCTTACAAA CACACACACA
18700
CATCCACAAA TGCTGAAAAA TGAAATCAAC CGAGCCACAC AGACATAAAG
18750
GAAAACATAA AAAG
A
TTTCC TACATGTGGG AAGCAAGTCA CA
G
A
A
A
G
G
G
G
18800 |
var(18765):[T:0.11]
|
REPEAT
G
A
A
G
G
A
G
A
T
T
G
G
A
A
C
A
G
A
A
A
T
A
T
A
T
A
C
T
G
A
A
A
G
C
A
A
G
G
A
T
G
G
C
T
G
A
A
A
A
T
18850
T
T
T
C
C
A
A
A
T
A
T
A
A
A
G
A
A
G
A
T
T
A
A
A
A
A
A
T
C
A
C
G
G
A
C
T
C
A
A
G
A
A
G
C
T
C
A
A
T
G
18900
G
A
T
C
A
G
A
A
A
A
A
T
A
A
T
T
T
C
T
A
A
A
A
T
G
A
C
A
A
T
T
A
T
A
G
G
A
T
G
C
C
A
C
T
G
G
G
T
A
C
18950
A
T
A
G
C
A
G
T
T
C
A
A
C
T
G
T
C
A
G
A
G
G
G
C
A
A
A
G
A
C
A
T
A
A
T
A
C
A
C
A
G
A
A
A
A
A
T
C
T
C
19000
G
T
A
A
G
G
A
A
C
G
G
G
A
A
A
A
A
C
A
A
A
A
A
G
C
T
G
T
G
T
C
T
T
G
C
T
A
G
A
G
G
A
A
C
A
G
T
G
A
T
19050 |
var(19001):[A:0.06]
|
NOT SCANNED
A
C
A
A
G
T
G
A
C
T
A
A
T
G
T
G
T
T
C
C
C
A
T
C
A
G
A
A
A
C
A
C
T
G
C
A
A
C
C
T
G
G
A
C
A
C
A
A
A
A
19100
G
A
A
T
A
A
C
A
T
T
A
A
A
G
T
A
A
T
A
A
A
C
G
T
A
A
G
A
A
A
G
A
A
G
A
G
C
T
C
A
A
C
T
G
A
G
A
A
G
G
19150
C
T
A
C
A
T
C
C
A
G
C
A
A
T
A
A
A
A
T
G
C
C
T
T
G
A
A
G
T
T
C
A
T
C
C
A
T
G
T
T
G
G
A
G
G
A
A
T
G
C
19200
A
C
A
T
T
G
T
G
C
A
C
T
C
C
C
C
T
A
A
A
C
A
A
A
G
A
A
A
C
C
G
G
A
A
A
C
T
G
T
A
A
G
A
C
T
T
T
G
G
A
19250
A
T
C
A
G
C
A
G
G
C
T
T
A
T
G
T
A
A
C
A
A
A
A
G
A
G
G
T
G
A
C
C
C
T
A
A
G
G
A
A
T
T
A
A
G
G
A
G
A
A
19300
G
A
A
G
A
A
T
A
G
A
A
C
A
A
G
A
A
G
G
G
A
A
C
T
T
T
C
T
G
C
A
G
C
C
T
A
T
A
T
A
A
T
G
A
A
G
A
A
C
C
19350
T
A
G
C
A
A
T
T
G
G
C
A
A
A
T
G
T
A
G
A
T
G
A
A
A
A
T
G
C
T
A
C
A
T
G
T
T
T
T
C
T
T
G
A
T
C
A
A
A
C
19400
G
T
T
T
A
T
A
T
C
T
T
T
T
T
A
A
A
T
G
A
G
A
G
T
T
G
A
C
G
A
G
T
T
G
A
A
G
C
A
A
A
A
T
G
A
T
A
C
C
A
19450
A
T
A
T
A
T
T
T
A
A
C
T
T
T
A
C
C
A
T
A
T
G
T
A
G
A
A
G
T
A
A
A
A
A
T
T
T
G
A
A
C
A
T
G
T
A
G
C
A
T
19500
A
A
A
T
C
A
T
G
T
A
G
G
G
A
T
T
A
A
T
T
G
G
A
A
G
T
G
T
A
C
C
A
C
T
G
T
A
A
G
T
T
T
C
T
T
A
C
C
T
C
19550
A
T
G
C
A
C
G
A
T
A
G
T
A
T
G
T
A
A
T
A
C
T
A
A
T
A
A
A
A
G
G
T
T
A
A
T
G
T
G
T
G
G
G
T
T
C
A
A
A
G
19600
G
G
A
T
A
T
T
G
C
A
A
A
T
C
C
T
A
G
A
G
C
A
A
T
C
A
C
A
A
A
G
T
T
T
T
T
A
A
C
T
C
T
G
A
G
G
T
T
T
G
19650
T
T
G
T
A
T
A
A
T
A
A
C
A
A
T
A
T
T
T
T
A
T
G
T
A
T
T
C
A
A
A
A
G
A
G
G
G
A
A
G
C
C
A
A
G
G
A
A
G
A
19700
A
A
A
A
A
A
A
G
T
C
T
T
T
A
A
A
G
A
G
C
T
C
T
G
G
C
T
C
T
T
A
G
T
A
C
A
T
C
C
A
G
T
T
G
C
T
C
A
T
T
19750
G
A
A
T
G
A
G
C
T
T
C
C
T
G
G
A
A
T
G
G
A
G
G
G
T
C
T
G
G
G
A
C
T
G
A
G
A
C
T
A
G
G
C
C
A
C
A
T
G
T
19800
G
T
A
G
A
G
C
C
A
C
T
A
G
A
G
A
C
A
C
A
A
T
G
T
T
G
G
A
T
C
C
C
C
A
T
G
G
C
C
C
A
T
A
A
T
A
C
A
T
T
19850
T
C
C
C
A
T
T
T
T
C
T
C
A
G
G
C
A
G
C
C
A
C
A
G
G
T
C
A
T
G
A
A
T
G
T
G
A
G
G
A
T
A
C
T
G
A
G
A
G
G
19900
T
T
G
G
A
G
C
A
A
C
G
T
T
C
T
T
G
G
G
A
G
G
C
A
T
A
A
G
G
A
A
G
A
G
C
G
A
A
T
G
C
T
T
C
A
A
G
A
T
C
19950
C
C
C
G
C
A
G
C
C
C
A
A
A
C
T
C
C
T
C
A
G
C
T
G
C
T
T
T
G
C
C
T
C
C
T
A
A
T
T
C
A
T
T
G
T
T
T
T
T
T
20000
G
C
T
C
C
T
C
C
A
T
A
G
C
T
G
T
C
C
G
A
C
C
T
C
T
T
C
A
G
A
T
C
T
C
T
T
A
G
T
C
T
T
C
C
T
G
C
C
A
T
20050
C
T
T
C
C
T
T
T
A
T
G
C
C
A
T
G
G
G
A
C
C
C
A
C
T
G
T
T
C
T
T
T
C
A
A
C
T
C
A
T
C
C
C
C
C
A
G
T
T
C
20100
T
G
G
A
G
T
G
G
C
T
G
T
G
G
A
C
A
G
C
A
G
A
G
G
A
T
A
G
A
C
T
G
A
G
A
G
C
A
G
G
A
G
A
G
A
A
G
G
T
C
20150
C
T
G
C
C
C
A
G
G
A
A
C
C
C
A
T
T
C
T
A
G
A
G
A
T
A
C
T
G
C
A
T
T
C
T
G
C
C
T
G
G
G
A
G
C
A
A
G
T
T
20200
T
T
C
C
A
G
G
G
C
A
G
C
T
T
T
G
A
G
A
A
G
T
C
T
T
G
C
A
G
A
A
A
C
A
A
A
C
C
T
A
C
T
T
G
A
C
C
G
A
C
20250
A
T
G
A
T
A
T
G
G
G
A
A
T
G
A
C
A
G
A
C
A
G
T
A
A
T
A
C
T
A
T
T
T
G
C
A
C
A
A
T
G
C
T
T
T
T
C
C
A
T
20300
G
G
G
A
A
A
G
G
T
A
G
A
G
C
C
T
T
T
T
C
A
C
T
A
G
G
T
T
T
T
G
A
G
T
A
C
A
T
G
G
A
G
T
G
T
G
A
G
A
G
20350
T
T
G
A
C
C
T
G
G
A
A
A
G
G
T
T
A
T
C
C
T
C
C
T
T
G
A
T
G
C
C
A
T
G
T
T
T
T
C
T
C
T
G
A
A
G
A
A
C
T
20400
A
C
A
T
G
T
T
C
G
T
T
G
C
A
A
C
T
C
C
C
A
C
A
T
T
A
G
A
A
T
A
T
G
A
A
G
T
C
C
T
A
C
C
G
A
G
A
G
A
G
20450
A
T
A
C
G
G
A
G
A
C
T
A
G
A
C
A
G
A
T
A
C
A
G
A
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G
C
A
T
T
T
G
C
A
T
G
T
G
A
A
T
A
C
A
C
A
A
T
C
C
20500
C
A
C
A
A
T
A
C
A
G
A
C
G
T
C
A
A
A
A
C
C
C
A
T
A
C
C
A
G
T
T
A
T
T
C
C
A
G
A
G
A
G
A
T
G
G
A
T
T
G
20550
G
G
C
A
G
A
A
G
G
C
A
G
A
A
G
G
A
G
A
A
T
A
C
T
C
T
G
A
T
C
G
T
T
T
T
T
C
G
G
C
C
A
C
G
T
G
T
G
T
G
20600
T
G
T
T
A
T
C
T
C
A
G
T
G
T
T
T
C
T
A
A
G
A
A
G
C
G
T
T
T
G
C
T
A
C
T
T
T
A
G
A
T
T
T
T
T
T
A
T
T
T
20650
A
A
A
A
A
A
A
A
T
A
G
T
A
A
T
A
A
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C
T
A
T
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A
A
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T
A
T
G
A
G
A
G
A
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G
T
G
C
A
G
A
G
A
G
G
A
T
T
20700
A
G
T
G
A
T
C
G
A
G
A
G
C
C
A
T
T
T
T
T
G
C
T
G
G
T
G
G
C
A
A
T
C
A
T
A
T
G
G
T
A
C
T
T
T
T
A
A
T
G
20750
G
G
A
A
T
A
T
T
A
G
A
A
A
G
G
C
A
C
C
G
G
T
A
A
T
G
A
C
C
T
T
G
T
T
G
C
A
G
C
A
C
A
A
A
G
G
A
G
A
G
20800
A
G
T
G
T
G
G
G
G
T
G
C
C
C
C
T
G
C
A
T
G
T
T
G
T
C
C
C
A
C
C
T
C
T
T
G
T
G
A
C
G
T
G
T
A
T
C
G
T
T
20850
T
T
G
G
A
A
T
T
T
C
C
A
G
T
G
G
C
T
T
G
A
T
C
A
T
G
A
A
C
T
A
C
T
G
C
A
G
G
A
A
T
C
C
A
G
A
T
G
C
T
20900 | Exon 4
G L I M N Y C R N P D A 82
G
T
G
G
C
A
G
C
T
C
C
T
T
A
T
T
G
T
T
A
T
A
C
G
A
G
G
G
A
T
C
C
C
G
G
T
G
T
C
A
G
G
T
G
G
G
A
G
T
A
20950
V A A P Y C Y T R D P G V R W E Y 99
C
T
G
C
A
A
C
C
T
G
A
C
G
C
A
A
T
G
C
T
C
A
G
A
C
G
C
A
G
A
A
G
G
G
A
C
T
G
C
C
G
T
C
G
C
G
C
C
T
C
21000
C N L T Q C S D A E G T A V A P 115
C
G
A
C
T
G
T
T
A
C
C
C
C
G
G
T
T
C
C
A
A
G
C
C
T
A
G
A
G
G
C
T
C
C
T
T
C
C
G
A
A
C
A
A
G
G
T
A
A
G
21050
P T V T P V P S L E A P S E Q 130
G
A
G
T
C
T
G
T
G
G
C
C
A
G
A
C
A
T
C
T
A
C
A
C
G
C
T
T
C
G
A
T
G
C
T
G
G
G
A
T
G
A
A
A
A
G
C
C
A
T
21100
G
G
A
A
A
T
T
C
C
C
A
C
T
G
A
T
G
C
A
G
C
C
G
C
C
T
T
C
A
A
T
G
G
T
A
A
A
C
G
G
A
T
G
C
T
C
G
A
G
T
21150
G
T
T
G
C
C
T
G
A
G
T
T
C
T
A
C
C
A
T
G
T
A
G
G
A
G
G
A
A
G
C
C
T
C
C
G
T
G
C
A
C
T
C
T
C
T
G
G
G
G
21200
G
A
G
C
C
A
G
C
G
G
A
G
T
G
A
T
T
T
C
T
G
G
T
G
C
A
A
C
G
T
G
G
T
T
G
G
G
C
T
T
T
G
T
C
T
T
T
A
G
G
21250
A
T
G
G
G
C
A
C
A
A
A
C
C
C
T
C
C
A
G
G
G
G
G
A
T
C
G
A
C
T
T
C
A
A
A
A
T
T
C
A
C
C
T
T
G
T
T
G
T
A
21300
A
A
A
C
G
G
G
C
T
A
C
C
T
C
A
G
T
G
T
C
C
C
A
G
C
C
A
A
A
A
T
T
T
T
T
A
T
T
G
T
A
A
C
A
T
G
C
T
G
T
21350
C
A
G
G
T
G
T
G
T
C
A
C
T
C
T
T
T
C
C
A
A
G
C
C
A
G
T
A
A
G
C
T
T
T
T
C
C
G
G
G
G
A
T
T
T
C
T
T
C
A
21400
A
G
T
A
G
C
C
A
G
C
A
T
T
C
A
G
A
G
C
A
A
T
C
T
T
C
A
G
C
A
T
T
G
C
A
G
A
T
T
C
T
G
A
G
A
A
A
T
G
T
21450
G
G
C
T
C
T
G
G
A
G
C
C
T
G
T
C
A
C
C
C
T
C
G
A
G
A
A
A
C
C
T
A
A
G
A
G
G
G
C
T
G
C
A
T
T
G
A
T
T
C
21500
C
A
T
G
T
G
G
C
C
C
T
G
G
G
T
C
T
A
T
G
G
A
G
C
A
G
T
A
C
A
T
G
A
G
C
T
C
C
C
A
G
T
G
C
T
C
T
A
A
G
21550
G
C
T
C
T
T
C
A
G
C
C
C
T
A
G
G
C
T
T
T
G
A
A
G
G
G
A
G
T
G
A
T
T
T
C
T
C
A
G
T
A
T
T
C
T
T
A
A
A
C
21600
C
T
C
T
T
T
C
T
G
A
T
G
A
C
A
C
T
T
G
T
A
C
C
T
G
T
G
A
G
G
G
G
T
C
T
A
G
A
G
A
G
A
A
A
G
A
G
T
A
G
21650
T
A
G
A
C
T
C
C
T
A
C
T
T
T
A
C
T
A
C
A
A
T
T
C
A
G
G
A
T
G
C
A
G
G
G
C
A
T
G
A
G
A
G
G
A
T
T
C
C
C
21700
T
C
T
C
T
C
C
T
C
C
A
A
G
G
G
A
A
G
A
A
G
C
T
T
T
T
G
G
C
G
T
G
C
A
C
A
C
A
T
C
C
C
T
G
A
G
A
A
G
C
21750
A
A
A
G
T
G
T
C
T
T
T
G
T
C
T
T
C
A
G
T
C
A
G
A
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A
C
A
T
A
G
G
A
C
C
G
T
T
T
T
C
T
G
C
C
C
C
A
T
G
21800
G
C
C
C
G
G
A
A
G
C
C
A
A
A
G
G
C
C
T
T
G
G
C
T
T
T
C
A
T
G
A
T
C
A
A
C
G
G
T
C
T
A
G
G
G
A
A
A
C
A
21850
T
G
C
A
A
A
A
T
T
T
C
C
A
T
G
T
C
T
G
T
C
C
C
A
A
A
C
T
C
T
G
C
C
C
C
C
G
A
C
A
G
C
C
A
A
T
T
A
C
C
21900
A
C
C
T
G
C
A
G
C
C
C
G
C
A
T
T
G
C
C
A
A
A
T
G
C
G
G
T
G
C
C
G
T
T
T
G
C
A
T
G
A
A
G
A
T
T
C
A
G
T
21950
A
G
A
G
T
T
T
C
C
T
A
G
A
A
A
G
G
T
G
C
T
A
C
C
T
C
G
T
G
A
G
C
T
C
A
C
T
T
T
C
C
A
A
T
G
A
G
G
A
A
22000
T
C
T
G
A
T
C
T
G
T
T
G
T
G
T
T
T
C
T
C
T
A
A
G
G
T
G
T
C
A
G
G
T
G
A
A
A
T
A
T
T
T
C
C
A
A
G
A
A
C
22050
T
T
A
C
T
A
C
A
G
T
T
C
T
A
G
A
A
T
G
G
G
A
G
G
A
A
T
C
T
G
T
T
G
C
T
T
T
G
G
T
G
T
T
T
G
T
T
T
G
T
22100
T
G
G
T
C
G
G
T
T
T
T
C
T
C
A
C
A
T
C
C
A
T
C
T
G
C
C
T
A
T
G
G
A
T
A
A
G
G
A
A
A
A
G
A
G
A
A
C
G
G
22150
T
C
G
T
A
A
T
T
C
T
C
A
T
A
G
A
C
T
C
C
T
T
T
C
T
G
G
T
T
G
T
G
T
C
A
C
A
A
A
T
G
G
C
T
T
C
A
C
A
T
22200
G
T
T
T
C
T
C
T
A
T
G
C
T
C
A
G
A
G
A
T
A
C
T
C
A
G
C
T
T
G
A
T
T
T
C
C
C
G
T
G
T
T
T
T
C
A
T
T
T
C
22250
A
G
C
A
C
C
G
A
C
T
G
A
G
C
A
A
A
G
G
C
C
T
G
G
G
G
T
G
C
A
G
G
A
G
T
G
C
T
A
C
C
A
T
G
G
T
A
A
T
G
22300 | Exon 5
A P T E Q R P G V Q E C Y H G N 146
G
A
C
A
G
A
G
T
T
A
T
C
G
A
G
G
C
A
C
A
T
A
C
T
C
C
A
C
C
A
C
T
G
T
C
A
C
A
G
G
A
A
G
A
A
C
C
T
G
C
22350
G Q S Y R G T Y S T T V T G R T C 163
C
A
A
G
C
T
T
G
G
T
C
A
T
C
T
A
T
G
A
C
A
C
C
A
C
A
C
T
C
G
C
A
T
A
G
T
C
G
G
A
C
C
C
C
A
G
A
A
T
A
22400
Q A W S S M T P H S H S R T P E Y 180
C
T
A
C
C
C
A
A
A
T
G
C
G
T
A
T
G
T
C
T
T
T
G
T
T
C
T
T
T
A
C
C
A
T
A
A
G
A
G
A
A
G
A
A
A
G
G
G
C
C
22450
Y P N A 184
A
A
G
T
G
A
A
G
T
T
T
C
T
G
T
T
A
C
A
A
G
A
G
A
T
G
T
G
T
C
T
C
A
A
G
C
T
G
A
G
T
T
C
T
C
C
G
A
A
C
22500
T
C
A
A
C
T
T
G
T
G
A
C
A
G
A
T
G
C
A
G
A
T
G
G
C
G
T
A
G
C
A
A
A
A
T
G
T
C
T
C
A
G
G
A
T
G
A
T
T
G
22550
C
C
T
T
G
G
A
G
C
T
A
A
G
G
G
T
C
T
G
A
G
A
G
A
A
G
G
G
A
A
A
T
G
T
T
A
A
G
C
T
C
C
C
T
C
T
C
C
T
T
22600
C
C
T
C
C
T
A
G
T
T
C
T
A
T
T
G
A
G
C
A
G
A
A
G
G
G
A
A
A
T
C
T
G
G
A
G
G
T
G
A
G
G
A
G
A
T
C
A
C
A
22650
T
T
A
T
G
A
A
G
A
A
A
G
T
C
A
G
A
A
T
G
A
C
A
A
A
G
G
A
C
C
A
G
A
C
A
C
T
T
A
G
A
T
T
A
C
C
C
T
T
C
22700
C
A
C
A
A
C
A
C
C
A
A
C
T
A
A
A
C
G
T
C
A
A
T
G
G
A
G
A
C
T
T
T
C
C
A
G
T
T
G
G
A
A
T
T
C
C
G
T
T
A
22750
T
T
C
T
G
G
C
T
T
C
C
A
C
T
T
C
C
T
G
A
A
G
G
G
A
A
G
G
T
T
G
C
G
T
T
T
G
C
C
T
T
T
T
C
T
C
T
C
T
G
22800
G
G
T
T
C
A
A
G
A
G
G
A
A
A
G
A
A
T
A
G
G
T
G
C
T
T
A
T
T
T
A
T
G
G
A
C
A
G
G
T
G
A
A
T
T
G
A
T
C
T
22850
G
T
T
T
C
T
A
T
A
T
C
T
A
C
G
T
A
T
A
T
T
C
C
G
A
T
T
G
T
C
A
G
A
A
A
A
A
C
A
C
T
C
G
T
T
C
C
T
A
A
22900
G
T
A
C
C
A
G
T
G
G
C
C
T
G
A
A
G
G
G
A
T
A
C
A
G
G
T
T
C
C
C
A
G
C
A
A
G
A
G
A
A
G
A
T
C
C
A
A
G
G
22950
A
A
G
G
A
A
G
G
C
A
G
A
T
G
A
G
A
G
T
C
A
G
C
A
C
A
G
A
G
A
G
G
G
A
T
G
C
T
G
A
A
A
A
G
T
A
A
A
A
G
23000
G
G
A
T
G
G
G
T
G
G
A
T
G
G
A
G
A
G
A
A
G
C
C
C
G
G
G
T
C
T
G
A
C
C
A
C
C
C
A
A
T
G
G
C
C
A
A
T
A
T
23050
T
T
T
G
G
C
C
A
C
A
A
G
C
G
A
C
T
A
C
C
A
G
A
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A
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A
T
G
G
A
A
A
A
A
T
G
G
T
T
T
C
T
A
C
A
T
G
T
G
23100 |
REPEAT
G
G
A
C
A
A
C
A
G
A
T
G
G
T
A
G
A
G
G
A
C
C
T
A
G
A
G
A
A
T
T
G
A
G
A
G
A
G
G
G
G
C
A
A
T
G
A
T
G
G
23150
G
C
T
C
C
A
C
T
C
C
G
C
A
G
A
T
G
C
C
T
T
G
G
C
T
T
T
C
T
T
C
C
T
G
G
A
T
A
C
C
C
T
T
C
C
T
G
C
A
C
23200
T
G
A
A
T
A
G
C
A
A
G
G
A
G
A
T
G
G
A
G
C
C
C
A
A
G
C
A
G
A
C
T
G
T
A
G
C
C
A
T
C
T
T
G
C
T
G
A
A
T
23250
G
G
A
G
G
A
G
A
G
G
G
A
T
T
G
G
A
G
T
T
T
G
G
G
A
T
G
A
C
T
G
T
G
G
T
A
G
C
T
G
A
A
A
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T
T
T
T
C
T
23300
A
G
G
T
C
T
G
C
T
A
G
A
A
A
T
A
A
G
A
A
C
T
G
G
T
T
T
G
T
G
T
G
G
A
G
G
A
A
A
A
G
A
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C
T
C
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A
C
A
23350
A
A
T
A
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G
C
A
T
A
G
A
A
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T
C
T
C
C
T
C
C
A
G
T
C
G
T
T
G
G
C
C
T
G
A
C
A
T
G
A
C
G
C
T
G
C
C
T
G
23400
T
G
C
A
C
A
G
G
A
A
A
T
G
G
T
T
C
C
A
C
G
A
G
A
A
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G
T
G
G
C
A
A
A
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A
A
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A
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T
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A
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T
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A
G
23450
A
A
A
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A
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C
A
A
G
T
A
C
A
A
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A
G
C
A
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A
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C
T
C
A
A
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A
A
A
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A
A
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A
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A
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A
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A
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A
23500
C
A
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A
G
C
A
C
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C
T
G
G
G
A
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A
C
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G
A
G
T
T
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T
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C
C
A
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C
T
A
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A
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C
A
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A
G
A
G
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C
C
T
23550
C
A
C
G
G
A
G
C
A
C
A
T
T
G
C
C
A
A
T
T
C
A
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T
G
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A
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A
C
C
C
C
A
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A
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A
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23600
A
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A
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23650
T
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A
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A
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C
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G
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A
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G
G
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C
A
A
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A
A
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23700
G
A
A
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T
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C
C
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G
T
G
A
G
A
G
G
A
A
A
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C
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A
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C
T
C
T
T
T
A
G
A
A
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T
A
A
A
C
A
A
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A
A
A
23750
G
T
C
G
A
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C
C
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C
A
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C
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A
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C
G
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A
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C
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C
A
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A
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T
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A
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C
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A
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T
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A
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23800
A
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C
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A
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A
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A
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G
T
A
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A
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A
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23850
A
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A
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A
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A
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C
23900
G
T
G
A
A
A
A
T
T
T
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A
C
A
T
A
T
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A
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T
A
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A
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A
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A
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T
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A
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23950
A
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C
A
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A
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A
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A
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A
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A
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24000
A
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A
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24050
A
A
A
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A
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T
A
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G
C
C
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G
C
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A
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A
A
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T
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A
G
A
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G
T
T
T
C
A
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A
G
G
A
A
A
24100
A
C
A
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T
A
C
C
C
A
A
C
A
C
A
C
A
A
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T
C
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A
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A
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A
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A
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A
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A
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A
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C
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A
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A
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24150
C
A
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A
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A
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A
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A
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A
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A
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A
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A
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A
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A
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A
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A
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A
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A
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24200
A
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G
C
A
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A
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A
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A
A
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T
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A
A
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A
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A
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A
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C
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C
A
C
C
C
C
T
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A
A
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24250
A
A
A
C
A
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T
G
A
A
A
T
A
T
A
A
A
A
T
T
A
A
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C
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A
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C
C
T
C
A
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A
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A
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A
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T
A
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A
A
A
A
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A
24300
T
G
A
A
A
A
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A
T
T
T
C
C
T
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C
A
T
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G
G
A
A
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A
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C
A
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A
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A
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A
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24350
G
T
T
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A
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G
A
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G
G
C
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A
T
A
A
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T
T
T
C
A
24400 |
REPEAT
A
T
T
A
C
G
A
A
G
A
A
C
A
T
T
A
A
A
A
A
A
A
A
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C
A
C
A
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A
A
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C
G
T
G
A
A
A
C
T
C
A
A
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G
G
A
T
C
24450
A
T
A
T
A
G
G
G
A
A
T
T
T
C
G
G
A
A
A
A
A
A
A
A
C
C
C
A
A
C
C
T
G
T
A
T
G
A
T
G
T
A
C
T
T
T
T
G
T
A
24500
C
A
T
C
A
C
A
G
T
T
C
G
A
A
G
G
T
A
A
C
A
A
G
G
C
A
A
A
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A
T
G
T
A
A
T
A
A
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A
A
G
A
A
A
C
C
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G
T
24550
C
A
C
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A
G
A
A
A
C
T
G
G
A
G
G
A
A
A
A
A
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A
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C
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G
T
G
T
C
T
T
C
C
T
A
C
A
A
G
T
A
C
A
C
T
G
A
T
24600
A
C
A
A
A
T
T
G
C
C
A
A
T
G
T
G
T
T
C
A
C
C
T
C
A
G
A
A
A
C
A
C
T
G
G
A
A
G
C
C
A
G
A
T
A
C
C
A
G
G
24650
G
A
A
T
A
T
T
G
T
T
A
A
A
A
T
G
A
T
A
A
T
C
A
G
G
A
A
C
A
A
A
A
A
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A
G
A
T
C
A
A
C
C
G
G
G
A
A
T
G
24700
C
T
G
A
A
T
C
C
A
G
C
A
A
T
A
A
A
A
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C
C
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T
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A
A
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G
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A
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A
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C
24750
A
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A
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C
A
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C
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A
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A
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G
A
A
A
C
T
G
T
A
A
G
A
A
T
T
G
G
A
A
24800 |
REPEAT
A
T
C
A
G
C
A
G
G
C
T
T
A
T
G
T
A
A
C
A
A
G
A
G
A
G
G
T
G
A
C
C
C
G
A
A
G
G
A
A
T
T
A
G
G
T
A
G
A
A
24850
G
A
A
G
A
A
T
T
G
A
A
C
A
A
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A
A
A
G
G
A
A
C
T
T
T
C
T
G
C
A
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C
C
C
A
C
G
T
A
A
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A
A
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A
A
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C
24900
C
A
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C
A
A
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G
C
A
A
A
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T
A
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A
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A
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A
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C
A
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A
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24950
A
A
A
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A
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A
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T
A
A
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A
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A
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A
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A
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T
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A
A
A
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A
A
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A
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A
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25000
A
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C
A
A
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A
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A
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T
T
A
A
C
T
T
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A
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C
A
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A
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A
G
G
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A
A
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A
A
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T
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A
A
A
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G
T
A
25050
G
C
A
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A
A
A
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A
C
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A
A
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G
G
A
T
T
A
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A
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C
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T
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A
A
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25100
A
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C
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A
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C
A
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A
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25150
C
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A
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A
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C
A
A
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C
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A
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G
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T
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A
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A
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25200
G
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G
T
A
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A
A
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A
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A
A
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A
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C
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A
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T
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A
A
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A
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A
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C
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25250
G
A
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25300
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A
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A
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A
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A
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25350
A
A
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A
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C
T
C
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A
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A
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A
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A
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G
G
A
A
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C
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A
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G
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C
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A
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A
A
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A
25400
C
A
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C
C
C
A
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T
C
A
G
G
C
A
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A
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A
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25450
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A
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G
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25500
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25550
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C
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A
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A
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A
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T
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C
A
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25600
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C
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C
T
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25650
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C
25700
A
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A
A
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A
C
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A
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25750
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25800
C
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A
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25850
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A
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25900
G
A
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25950
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C
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A
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26000
A
C
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A
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A
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A
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26050
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A
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A
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C
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26100
C
A
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A
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A
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A
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G
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C
C
A
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26150
T
T
A
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C
T
C
A
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T
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T
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T
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A
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A
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26200
A
A
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26250
G
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26300
A
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A
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A
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A
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26350
G
T
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G
G
G
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C
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C
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26400
G
A
A
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C
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G
26450 | Exon 6
G L I M N Y C R N P D A V 197
G
C
A
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C
C
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A
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A
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A
C
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A
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A
T
C
C
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C
A
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G
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A
G
T
A
C
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G
26500
A A P Y C Y T R D P G V R W E Y C 214
C
A
A
C
C
T
G
A
C
G
C
A
A
T
G
C
T
C
A
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A
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A
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A
A
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A
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T
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C
G
C
C
T
C
C
G
A
26550
N L T Q C S D A E G T A V A P P 230
C
T
G
T
T
A
C
C
C
C
G
G
T
T
C
C
A
A
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C
C
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A
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T
C
C
T
T
C
C
G
A
A
C
A
A
G
G
T
A
A
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G
A
G
26600
T V T P V P S L E A P S E Q 244
T
C
T
G
T
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C
C
A
G
A
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A
T
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A
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26650
A
A
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A
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G
A
G
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26700
G
C
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T
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A
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T
A
C
C
A
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A
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C
C
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T
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A
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T
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G
G
G
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A
G
26750
C
C
A
G
C
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G
A
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T
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A
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T
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G
T
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A
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T
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A
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G
A
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26800
G
G
C
A
C
A
A
A
C
C
C
T
C
C
A
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G
G
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C
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A
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T
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A
A
A
A
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A
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T
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T
T
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A
A
A
A
26850
C
G
G
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C
T
A
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C
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A
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T
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C
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A
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C
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A
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T
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A
T
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T
A
A
C
A
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C
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A
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26900
G
T
G
T
G
T
C
A
C
T
C
T
T
T
C
C
A
A
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C
C
A
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A
A
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C
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G
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A
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T
T
C
A
A
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26950
A
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C
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C
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A
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A
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A
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A
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C
27000
T
C
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G
A
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A
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C
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A
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A
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A
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C
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A
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A
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A
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27050
G
T
G
G
C
C
C
T
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G
G
T
C
T
A
T
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G
A
G
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A
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A
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A
T
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A
G
C
T
C
C
C
A
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T
G
C
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C
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A
A
G
G
C
T
27100
C
T
T
C
A
G
C
C
C
T
A
G
G
C
T
T
T
G
A
A
G
G
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T
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A
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A
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A
A
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27150
T
T
T
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T
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A
T
G
A
C
A
C
T
T
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T
A
C
C
T
G
T
G
A
G
G
G
G
T
C
T
A
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A
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A
G