IL22RA2 Color FASTA
The longest form of insertion/deletion sites is shown in the FASTA sequence and contain a '-' as the alternate allele in the variation tag.
*Display courtesy of
GeneSNPs
TTCCCGTTCC TTTAGCTTAA TTCTTGTAAA TTCATGGCAG TTGCTAAAAT
50
CACATTCCTT TTTT
T
T
G
A
T
T
C
A
C
T
A
G
A
C
A
T
G
T
G
A
T
A
A
G
G
G
C
T
T
A
C
T
G
T
G
T
100 |
REPEAT
C
C
C
C
A
G
C
C
T
T
G
T
C
C
T
A
A
G
T
G
C
T
A
G
A
G
T
T
A
A
A
G
C
A
G
T
G
A
A
C
A
A
A
A
C
A
C
A
T
A
150
A
C
A
T
C
C
C
T
G
A
C
C
T
C
G
T
G
G
A
G
C
T
T
A
T
A
T
C
C
T
A
G
T
T
G
G
G
G
A
G
A
T
A
G
A
C
A
A
C
A
200
A
G
A
A
T
A
A
A
A
T
G
A
A
A
C
A
T
A
G
C
C
T
G
C
C
A
A
A
T
G
A
T
G
A
T
A
A
A
T
G
T
T
T
T
G
G
A
A
A
A
250
C
A
A
A
C
A
G
A
T
A
A
A
G
G
T
G
C
C
A
G
G
G
A
C
A
G
C
T
G
T
T
G
G
G
G
A
C
T
G
C
T
A
T
T
T
T
G
G
G
T
300
G
T
C
A
T
A
G
A
A
T
T
C
A
C
T
G
A
T
A
A
G
A
T
A
A
T
A
T
T
T
G
A
G
C
A
G
A
G
A
C
A
T
G
A
A
G
G
A
G
G
350
T
G
A
G
G
G
A
G
T
G
A
G
C
C
T
G
G
A
C
A
T
C
T
C
A
G
G
A
A
G
A
G
C
A
T
T
G
G
A
G
C
A
G
A
G
G
G
A
A
C
400
C
T
T
G
C
T
A
A
T
G
T
A
G
G
G
A
T
G
T
G
C
C
T
G
A
T
A
T
G
T
T
T
G
A
G
A
A
A
C
A
G
C
A
A
A
A
A
G
A
C
450
C
A
C
C
C
A
G
G
A
G
G
G
A
G
C
A
C
C
A
T
G
G
G
T
T
G
G
G
A
G
G
A
G
A
G
C
A
G
T
A
G
G
A
A
A
T
A
A
A
T
500
T
T
A
G
A
G
G
T
A
A
C
A
G
G
A
C
C
T
G
G
T
T
A
T
A
T
A
G
G
G
C
T
T
A
G
T
A
A
G
G
G
A
C
T
G
G
A
A
A
A
550
A
T
G
T
T
G
A
C
T
T
T
C
A
A
T
C
T
G
A
G
T
G
A
G
A
T
G
G
G
A
A
G
G
C
A
T
C
A
C
A
G
G
G
T
T
C
T
G
A
A
600
T
A
A
A
A
T
G
T
T
C
T
A
T
T
C
T
G
A
C
A
T
T
T
A
A
T
A
G
G
A
A
C
A
C
T
C
C
A
C
C
T
G
A
T
G
C
A
G
A
G
650
A
A
C
A
G
T
G
A
C
A
G
A
G
G
C
A
G
G
C
A
G
A
C
C
A
G
T
A
A
G
G
A
G
G
C
T
G
T
G
G
C
C
A
C
A
G
T
C
C
A
700
C
A
C
A
A
G
A
G
A
T
G
A
T
G
A
T
A
G
C
A
G
G
T
T
A
C
C
A
A
A
T
G
G
G
T
A
C
A
G
T
G
G
A
G
G
A
G
G
T
G
750
A
A
A
A
C
C
A
G
T
T
G
G
A
T
T
C
T
G
G
T
T
A
T
G
C
C
A
T
G
A
A
G
A
T
A
TTTTC AGGATCAAAC
800 |
var(766):[T:0.10]
AATACATACA AACATACTGG TGCATGGGCA TAATGATTGA TGATATCTGG
850
TAGGGGTTTC AAGGTGACCT T
G
G
G
T
G
A
A
G
A
A
T
A
A
T
C
A
A
A
G
C
T
A
C
A
T
A
T
T
G
900 |
REPEAT
G
G
T
A
C
A
A
T
G
T
A
C
A
T
T
A
C
T
C
G
G
G
T
A
A
G
A
G
A
T
G
C
A
A
T
A
A
T
A
T
C
T
C
A
G
A
C
T
T
C
950 |
var(938):[A:0.01]
A
C
C
A
C
T
G
T
G
C
A
A
T
C
C
A
T
C
C
A
G
G
T
A
A
C
C
A
A
A
A
A
C
C
A
C
T
T
G
C
A
C
T
A
T
T
G
C
A
C
1000
A
G
C
T
A
C
T
G
A
A
A
T
A
A
A
A
A
A
A
A TA
A
ATATTTT TTAAATGTTA CCACTCCTTT
1050 |
var(1023):[C:0.48]
ATGTTTTGGT TT
T
CAGAAAT AAATTTTAAA AAATTTTTTA AAGAATAATC
1100 |
var(1063):[C:0.07]
AAAGCAAAAT CAATAGCATC TTTTATCCAG AAAAATAAGA GTGAAGAGCA
1150
GGAAAGGTTA ACCTCATTAA GCCCTATGTC CTATGAGTGG AGATTTTAAA
1200
TAATATATTA GTGATCACAG TCCAAAAACT CAGATTAGTC ATTGTGCTTA
1250
TCACCTGTGT TTGAATAACA ATGTTTCTTT TTCTTTTCTG AATTCAAGTT
1300
CACAAACCAT TTTGAATTTT TGCATGCCAA TTA
T
TTCCAG AATGCCGAAC
1350 |
var(1334):[G:0.09]
TGCTTAAAGG ACATGAATAT TACTCGGTGG AGCTATTAAT GTCCCAGCAA
1400
ATAAGAAAGA ACAAGTTGTT TCCCTGTTGT TGGCTCTACA GCTCTATAGT
1450
TTTCCAGAGA GGGAGAAGGG TGGTGTTCAG ATTATCATTC ATGATGAAAC
1500
TTTTAAAAGA TGCTCAGCTG CCCACCAAAT CATAGGATGA AGGAAAGGGC
1550
CTAGCAGAAA CACAGTTGCT CTGACTTCCC TTCAATGGAC AGCACCAAAG
1600
TCATACTGAA CACCAGTTTT TAAACACTTC TCTGAAAAAC AATAAGAAAC
1650
ACTTAG
C
CCT TTGCTACCAA GACCTGGTTG AAGAAAATG
C
T
G
T
T
G
G
T
T
C
C
1700 |
var(1657):[T:0.01]
|
REPEAT
C
T
G
A
G
G
G
C
T
G
G
C
T
C
T
G
T
A
G
T
C
T
T
G
T
T
C
A
T
T
T
C
T
G
C
A
T
C
C
C
C
G
A
T
G
T
C
T
A
A
1750
C
A
C
A
G
T
G
C
C
T
G
G
C
A
T
A
T
A
A
C
A
G
T
T
G
C
T
C
A
A
T
A
A
A
C
A
T
T
T
G
T
T
T
G
A
C
T
G
A
A
1800 |
var(1761):[A:0.01]
|
var(1769):[C:0.10]
T
A
A
A
C
GATTC GAGAAGCCAA TGGACAAATG TTCTTTGACA TCATTCTATC
1850 |
var(1805):[T:0.01]
CCTTTATGGA ATGTCTATTA CAAGCAAAGA ATAACACAAG AGGAGTTTCA
1900
TAATACTCCT
C
A
G
G
C
C
C
T
G
A
G
G
C
T
A
A
C
C
A
G
A
T
C
T
G
A
T
T
T
C
A
G
C
C
C
T
C
A
C
T
1950 |
REPEAT
| Exon 1 |
UTR
T
T
A
C
C
A
C
T
A
C
T
C
G
C
T
A
T
A
G
A
G
C
C
C
T
G
G
T
C
A
A
G
T
T
C
T
C
T
C
C
A
C
C
T
C
T
C
T
A
T
2000
C
T
A
T
G
T
C
T
C
A
G
T
T
T
C
T
T
C
A
T
C
T
G
T
A
A
C
A
T
C
A
A
A
T
G
A
A
T
A
A
T
A
A
T
A
C
C
A
A
T
2050
C
T
C
C
T
A
G
A
C
T
T
C
A
T
A
A
G
A
G
G
A
T
T
A
A
C
A
A
A
G
A
C
A
A
A
A
T
A
T
G
G
G
A
A
A
A
A
C
A
T
2100
A
A
C
A
T
G
G
T
G
T
C
C
C
A
T
A
A
T
T
A
T
T
A
G
A
T
C
T
T
A
T
T
A
T
T
G
A
C
A
C
T
A
A
A
A
T
G
G
C
A
2150 |
var(2108):[C:0.44]
T
T
A
A
A
A
T
T
A
C
C
A
A
A
A
G
G
A
A
G
A
C
A
G
C
A
T
C
T
G
GTAAGTAAAC
T
T
T
A
T
T
T
A
T
T
2200 |
REPEAT
T
A
T
T
T
A
T
T
T
A
T
T
T
T
T
T
T
G
A
G
A
T
G
G
A
C
T
C
T
C
G
C
T
T
T
A
T
C
G
C
T
G
C
C
C
A
G
A
C
T
2250
G
G
A
G
C
G
C
A
G
T
G
G
C
G
C
G
A
T
C
T
C
G
G
C
T
C
A
C
T
G
C
A
A
A
C
C
T
C
A
C
C
T
C
C
T
T
G
A
C
T
2300
C
A
A
G
C
A
A
T
T
C
T
C
C
T
G
C
C
T
C
A
G
C
C
C
C
A
C
T
G
A
G
T
A
G
C
T
G
G
G
A
T
T
A
C
A
G
G
C
A
C
2350
A
C
A
C
C
G
T
C
A
C
G
C
C
T
G
G
C
T
A
A
T
T
T
T
T
G
T
A
T
T
T
T
T
A
G
T
A
C
A
G
A
C
G
G
G
G
T
T
G
C
2400 |
var(2356):[A:0.01]
A
C
C
A
T
G
T
T
G
G
C
C
A
G
G
C
T
G
G
T
C
T
G
G
A
A
C
T
C
C
A
C
A
C
C
T
C
A
A
A
T
G
A
T
C
C
A
C
C
C
2450
A
C
C
T
C
C
G
C
C
T
C
C
C
A
A
A
G
T
G
C
T
G
A
G
A
T
T
A
C
A
G
G
T
G
T
G
A
G
C
C
A
C
C
G
T
G
T
C
T
G
2500 |
var(2461):[T:0.45]
G
C
C
ACATCTT GTAGATAAAC TTTAAAAATC TTTTTTCTTT GTTATGAACA
2550
ATTTTAAGTA CATACAAAAG TAGAGTATAA TAAACCTGAC ACCCAATTTC
2600
AACAGTTATC AGCTCATGGA TGGTAACCCC
C
TTTCCCAGG CCTT
T
G
T
A
T
T
2650 |
var(2631):[T:0.01]
|
REPEAT
A
T
T
T
T
G
A
A
G
C
A
A
A
T
C
C
C
A
G
A
C
A
T
G
A
C
A
C
C
A
T
T
T
C
A
T
C
T
G
T
A
G
T
A
C
T
A
T
A
A
2700
T
A
G
G
T
A
G
C
T
C
T
A
A
A
A
A
A
A
A
A
T
A
A
A
A
A
T
A
A
T
A
A
C
C
A
A
A
A
T
T
C
C
A
C
A
T
C
A
C
A
2750 |
var(2707):[C:0.01]
C
C
T
A
A
A
A
A
C
A
A
T
G
A
A
A
A
A
T
G
A
T
T
C
C
T
T
A
A
T
TAGATAAATG GTTGGTCTGC
2800
TGGAAGCCAC AAGAAGAAAG GAAGAAGAGA ATCAAATCTG TTCAAGACAG
2850
GGGCTTAAGC AAGTTCTCTC CAGAGTCAAC ACGATGATGG AAATACCCGT
2900
TGTCACCGTC AAGGTGGACT CTCCCTGCTG CGGAGTGGGG CCGAGGTCGG
2950
GGGAGGGCAG GGAATGAAGC CAGCATTTCA TGCCTGAAAG GAGGCAGAGC
3000
GGAGATCCCC TAGTGACTAA AACTTTCTTA CTTCCCAAAC AAAACAGCAT
3050
TTCATTTGAA ACAATTCTGT ACAAATTCTT CTGCTTCCAG ATTGATGGGA
3100
AATTAGAATT TAATTTTATC TTTTCATCTA CCTTGAGGCC TTGTTGACAG
3150
TGTTGGCTTT TATGCAGGTT CTATTACACA ACTAGAGCTA ATTGAACAGT
3200
GACAGAACTG GTCTGGTTTG TGAAATTTAA TAGAGCACCA AAGCTCACGT
3250
TTTGGGGAGA ATTCAGTTCT TAAATATGTT TTGCTTATCC CACTCCGCCT
3300
AATTTCCCCT CATTTGTTTG ACAAAGTCAG CAACCCAGTG GAAACCTCAA
3350
TTTCGTTCTC TGCTGCTCTC ATCATAAAAC CTCGAATTTA AATATTTTCC
3400
TTTTATTCTT AGCTGGAACT TGGAGCAATT TGGTGGCTTC AAAATGAGAT
3450
CTATTGGTAT TGAAGCCATT GAACATCAAT AGTGCAAACC CACATTATCA
3500
TCCCCCATTT AAATACCAAA GTAAATGTGA AGTGGTAAAC ATTAGCAGGG
3550
AAGTGAATAA CAATGCTGAG AAGGTTGCAA GCTAAGGAGC ATGAAGAGGT
3600
GAAAAGGGAA CATAAAACGT GCTGCATGTT TCTTCTTTCA AAGCAGAAGC
3650
TACCTTATAA GCACCAAAAA CTTCAGCTGG AGGAGATACA AGCCTGGATT
3700
CAGAAGACTG CCGTAGAACA GAGGCACTGG GAAACCTGAT GTTATCCACA
3750
CAAACCTTTC CACATAGGGC TGGCCTCAGA AAGCATGCAG CGCAACTGCC
3800
CTCCAATAAC TGAAATTTGT TAAATGAAAA TTGATAGTGG CCTGGTCCAC
3850
TGGGATCTGG TTTCTGAGGA AATTTCTGAT AAGCTCTCTT CTAAGACCCT
3900
TTGCTCAGGA ATAAGGTTTT CCCTG
C
GTGG CCCCAGCTCC ACCCAAGGCC
3950 |
var(3926):[T:0.23]
TCACAGTCTC AGGCACCCGA GTGTCTAGAA ATGTTCACAG GTGCTGGGTC
4000
ATGGGGTTGG GATGGAGGGT CTACACTTGA GAACAACTCC TCTGCTCCTG
4050
TCTGTATGCA GAAGGCCATT CTTCCCTTTC TCTTTGAAGA CTCTGCCTCC
4100
TCCACATCAG CAGCACCCAA CCCTCTCCTT TTAGCACTTT CATTTTACCT
4150
GCTTCCCCTC CTACATTCTA GTCTTGGTTA ATGGTTGTGA TGGAGGGTGG
4200
GAGGCAAAGT GGCTTTGCAA GCCGGCTTCT GAAACTTTTC ATCTCCCATT
4250
TAAGAAGGAG AAGAAAAAGA CAGAGAAGGT TAGATGAATA GAAGTTGTAA
4300
CCCTGCTGTA GCTCCTTATT
C
TCTA
C
T
T
T
T
C
C
C
T
T
G
A
G
A
A
G
C
A
A
G
C
T
T
A
A
4350 |
var(4321):[G:0.10]
|
REPEAT
G
G
A
A
G
G
C
A
G
G
G
G
C
A
A
T
G
T
C
T
C
T
C
T
T
A
T
C
T
G
C
T
G
C
T
G
C
A
T
C
C
T
T
G
C
T
G
C
T
G
4400
A
G
A
C
T
A
A
T
T
C
C
T
A
G
T
T
T
A
T
G
G
T
A
G
G
A
C
A
G
C
A
A
A
T
A
T
T
T
G
T
G
A
A
A
T
G
TTAT
4450
TGGATAGCTG CATGGATGGA TACTGCTTAG CAGCCATCAT TATTCCTTAC
4500
TAAAGGAGCT ATTCTACCAA GAACTTGAAA GAGACTATAC AAGAGAAAAT
4550
AGAAACCAGT ATACATTTCC CCTTTTGATC TAAAGAGCCT CTCTTTTTAA
4600
CAACAACAAA AAAACCTTTA TGACT
T
G
C
G
G
A
G
G
C
T
G
A
A
G
C
A
A
C
T
T
C
A
T
T
T
4650 |
REPEAT
|
var(4629):[A:0.08]
T
T
A
G
A
T
G
C
T
A
A
T
C
T
G
C
C
A
T
G
T
T
G
A
C
T
T
C
T
G
A
T
T
A
A
T
C
C
T
T
T
T
T
C
A
G
G
A
A
G
4700
G
C
T
T
C
T
A
A
G
A
T
T
T
C
T
A
G
T
T
T
A
T
C
G
A
T
T
G
T
T
C
C
T
T
G
T
A
T
G
A
G
A
A
C
A
C
A
T
A
C
4750
T
T
G
T
C
A
T
A
A
G
T
C
C
T
G
C
C
T
G
T
A
C
G
T
C
A
A
A
A
C
C
A
C
C
T
T
G
A
T
G
T
T
A
T
G
A
T
A
C
T
4800
T
C
A
A
T
T
G
T
C
A
T
A
T
A
C
A
T
C
C
C
T
T
C
T
G
A
A
T
C
A
C
G
C
A
G
G
C
C
C
T
T
T
C
C
C
G
G
T
G
G
4850
T
A
T
G
T
A
A
G
C
C
C
T
G
G
G
T
C
T
G
T
T
G
C
G
G
G
A
T
G
A
T
C
A
A
A
G
A
C
T
G
A
A
G
A
G
A
C
C
G
A
4900 |
REPEAT
A
A
G
T
T
C
A
G
G
A
A
A
G
T
T
T
A
T
T
A
A
A
T
T
A
A
G
G
T
G
A
T
C
A
C
C
G
G
C
T
C
A
G
C
T
A
G
T
C
T
4950
G
A
G
C
C
C
C
A
A
A
C
A
A
A
G
G
G
C
T
T
T
T
C
C
T
A
C
T
T
T
T
A
A
A
T
A
T
C
T
T
A
A
G
G
T
G
G
G
A
A
5000
C
T
A
C
G
T
G
A
G
G
C
G
G
G
A
A
T
C
G
A
G
T
T
A
C
A
G
A
A
G
C
A
A
G
A
A
A
C
A
A
A
G
G
C
A
G
T
A
T
T
5050
A
C
A
A
C
G
T
T
T
G
T
T
A
C
A
T
T
T
T
G
A
G
A
A
A
G
A
C
A
T
G
T
C
T
T
G
C
A
G
C
C
T
A
A
A
C
T
T
A
T
5100
C
A
G
T
C
T
T
G
T
G
A
C
C
C
T
G
C
A
G
T
C
A
T
G
C
A
G
G
A
A
C
T
C
A
C
T
G
G
G
C
C
T
G
T
A
A
T
A
A
A
5150
C
T
T
T
G
A
G
G
A
A
T
G
T
G
G
A
G
T
T
G
G
G
G
A
G
T
A
T
A
G
A
T
A
A
G
G
T
C
C
A
C
T
G
T
C
C
A
C
A
G
5200
A
G
A
G
A
A
G
A
C
A
G
G
C
T
G
T
T
A
A
T
A
T
T
C
C
C
T
T
T
T
A
A
C
G
T
G
A
A
T
G
T
A
A
G
G
C
A
G
G
G
5250
G
TCACATTTT GCAGGAACTT TAAAAGGATT TTAAAATTTG TATTACTACT
5300
ACTCTTAGGT TATAGTTGAT TTCATTAATT CCTTCTTCA
T
T
T
C
C
C
C
C
T
T
T
5350 |
REPEAT
T
G
G
T
G
C
T
C
G
A
C
A
C
A
A
A
T
G
T
A
G
A
T
T
A
A
T
A
A
A
G
A
G
C
A
C
C
A
C
A
G
T
T
A
G
C
T
A
T
T
5400
T
C
T
T
C
T
T
G
A
G
T
G
G
G
T
A
C
A
T
A
C
T
C
A
T
C
T
T
G
G
G
A
T
A
C
C
A
G
T
T
G
G
T
A
C
T
T
T
T
G
5450
C
A
G
A
G
C
C
T
T
T
A
T
T
C
G
G
A
T
G
G
T
G
G
T
A
T
G
T
C
T
G
T
C
T
A
C
C
A
T
T
G
A
G
T
C
T
A
T
G
G
5500
T
G
G
A
T
T
G
G
A
T
G
C
T
T
C
C
G
A
T
T
A
G
A
A
A
T
G
G
C
A
A
G
A
G
A
C
A
G
G
G
A
A
G
C
A
G
T
A
G
G
5550 |
var(5519):[A:0.21]
C
A
T
C
C
A
C
C
T
T
T
T
A
T
G
G
C
C
A
C
A
A
A
G
C
C
T
A
G
T
A
T
T
A
C
A
G
T
T
T
T
A
A
A
G
C
C
T
C
C
5600
A
A
A
C
C
A
T
G
A
A
A
A
C
C
G
T
C
C
T
C
C
A
A
A
G
A
G
T
G
A
A
C
T
C
G
G
G
T
T
C
C
A
A
C
C
A
G
A
C
C
5650
A
T
G
T
C
T
G
A
A
C
C
A
G
A
A
C
A
T
G
A
G
C
T
A
A
C
T
T
C
C
G
C
A
T
C
C
T
G
G
C
A
G
T
G
A
T
T
T
C
C
5700
A
T
G
A
C
A
G
C
T
T
T
T
C
C
A
T
T
G
T
C
A
T
C
A
A
T
T
T
G
T
A
A
G
C
A
G
C
A
A
T
T
T
G
T
T
A
A
A
T
T
5750
A
A
G
T
T
T
T
C
C
A
C
A
A
A
C
C
C
C
C
T
T
C
T
G
A
A
G
C
T
A
A
A
A
C
A
T
A
A
T
T
C
A
G
T
A
C
T
A
A
C
5800
C
T
G
T
T
C
T
G
A
T
A
A
A
T
G
G
C
A
T
C
T
C
T
C
A
T
C
T
G
G
G
T
T
G
C
C
T
G
T
A
T
G
G
C
T
A
G
C
A
A
5850
G
T
C
T
A
A
G
G
C
T
C
A
G
G
C
T
G
T
T
T
C
A
T
T
G
A
C
T
A
T
A
A
T
T
T
C
C
A
G
A
A
C
T
G
C
T
T
G
C
A
5900
A
C
C
T
T
A
T
G
A
T
G
T
G
G
T
T
T
A
A
C
A
T
A
T
A
A
A
T
A
G
G
A
G
T
A
C
A
G
T
A
T
C
C
C
C
A
T
G
A
C
5950
C
C
A
T
C
T
T
G
T
G
C
C
C
A
G
G
G
G
G
C
C
A
T
T
C
A
T
T
A
T
C
T
T
T
C
C
A
G
C
C
C
C
C
T
A
T
T
T
C
A
6000
A
T
G
T
C
C
T
T
T
T
T
A
A
T
G
T
T
A
G
T
A
T
T
T
A
T
T
T
T
T
T
C
C
T
C
A
G
T
A
C
T
T
A
T
T
T
T
T
G
T
6050
A
A
A
C
A
C
A
T
T
T
C
T
T
T
T
G
A
C
T
C
T
T
T
T
T
C
T
G
C
C
T
T
C
A
T
C
A
T
A
G
A
C
C
A
G
A
T
A
G
C
6100
T
T
A
G
A
T
C
T
T
C
C
C
C
T
T
G
C
T
G
C
A
G
G
G
G
G
A
G
T
A
G
C
A
A
A
A
A
G
A
A
T
G
G
C
C
T
T
A
T
T
6150
G
T
T
C
C
T
A
A
T
A
T
A
C
A
T
G
C
C
C
C
T
G
T
C
C
A
T
T
T
A
T
C
G
G
T
T
A
G
T
A
A
T
T
G
A
T
A
A
G
C
6200
C
T
T
T
G
T
T
C
C
A
C
A
G
A
T
C
C
T
A
T
A
T
A
A
T
C
C
T
G
C
A
G
G
T
G
C
T
C
T
C
C
A
A
A
C
A
G
T
T
G
6250
G
A
G
C
T
T
C
T
A
A
T
T
G
G
T
A
C
C
A
T
G
A
T
T
G
A
T
T
T
A
G
T
G
T
T
G
G
G
A
A
C
T
G
C
A
A
A
A
A
G
6300
G
G
A
T
T
A
A
A
G
T
G
A
C
A
C
A
G
A
G
G
A
A
T
C
A
T
C
T
A
T
A
A
A
G
C
T
T
C
T
C
C
A
T
T
G
T
G
T
T
C
6350 |
var(6325):[G:0.09]
T
G
T
T
C
T
C
A
G
A
T
T
C
T
T
C
A
A
A
A
T
A
T
T
G
T
T
G
A
C
C
T
A
G
G
C
A
A
G
T
T
G
T
T
T
C
C
C
C
T
6400 |
var(6370):[C:0.09]
A
T
C
T
G
G
T
T
C
T
G
A
A
A
G
G
A
C
T
T
G
C
C
C
C
A
A
C
A
G
G
C
A
A
T
A
C
A
G
T
A
T
T
T
T
C
C
A
A
T
6450
G
A
T
G
G
G
G
T
T
C
C
T
T
A
A
T
A
G
C
C
A
A
A
C
A
C
T
T
G
G
A
T
T
T
G
C
A
T
T
G
A
A
T
T
T
T
G
T
A
A
6500
C
A
A
A
T
T
C
A
G
G
C
A
A
G
G
T
A
A
A
A
T
T
G
T
C
T
T
G
C
A
G
C
A
T
C
A
A
T
T
C
T
C
T
G
G
C
T
T
C
C
6550
C
A
G
G
G
C
C
A
T
T
G
A
T
C
T
C
T
C
A
T
A
T
T
A
G
C
A
C
C
T
C
C
A
C
A
T
A
C
A
T
A
A
C
A
G
G
A
A
G
T
6600
A
A
C
T
C
C
T
A
A
A
T
T
G
T
T
A
G
C
A
A
T
A
C
T
T
T
T
G
G
C
T
A
G
C
T
G
G
A
C
A
A
A
C
A
G
A
T
T
T
T
6650
C
A
G
T
T
G
A
T
A
T
A
G
G
A
G
G
A
A
T
T
T
G
A
A
T
T
T
T
T
G
A
T
A
C
T
T
C
A
G
A
A
T
T
A
A
A
G
T
G
T
6700
T
C
A
T
T
G
A
A
A
G
A
T
T
T
A
T
A
A
A
A
C
C
T
G
A
A
C
T
G
T
T
G
T
A
T
T
G
G
G
C
T
A
A
G
T
T
G
A
A
C
6750
T
T
G
A
G
T
C
C
T
T
T
G
G
G
T
T
T
T
C
T
T
T
G
T
G
A
T
G
A
C
C
A
G
A
G
G
A
A
T
A
C
C
A
A
G
T
C
C
T
A
6800
G
G
A
G
A
G
C
T
C
C
T
G
C
C
T
G
A
T
C
A
A
A
G
G
T
T
A
G
T
A
A
T
C
C
T
T
T
A
T
G
C
C
C
T
T
T
A
G
T
C
6850
C
A
G
A
A
A
G
T
C
A
T
A
T
T
T
G
G
C
T
T
T
A
G
T
A
T
T
G
T
C
A
G
A
T
T
G
A
G
T
G
G
G
T
A
G
C
A
T
G
T
6900
T
C
C
A
G
T
T
G
T
G
T
A
C
C
C
T
A
T
C
T
T
C
T
C
C
T
C
T
T
G
G
C
T
G
G
C
A
A
A
C
A
G
A
G
C
A
G
C
C
C
6950 |
var(6936):[:0.10]
|
var(6940):[G:0.04]
T
T
C
C
A
G
T
G
T
A
T
A
G
G
T
G
C
T
G
A
T
T
A
A
A
T
T
C
A
T
G
T
G
T
G
G
T
C
C
A
C
T
G
A
T
T
A
T
C
A
7000
C
A
A
T
C
A
G
G
G
C
A
C
T
C
T
T
T
T
T
C
G
G
A
C
T
C
T
C
C
T
A
T
T
A
T
G
G
C
C
T
T
G
G
T
G
G
C
T
C
T
7050
G
C
T
G
C
T
G
A
C
T
C
T
T
T
C
T
T
G
T
C
C
T
A
G
A
T
T
T
T
T
A
C
A
G
A
T
G
G
T
C
C
A
A
A
T
A
T
T
A
T
7100
T
T
A
A
T
T
T
A
C
T
G
A
G
A
T
G
T
G
C
A
G
C
T
T
G
G
C
A
G
G
C
A
T
C
A
A
A
A
T
A
T
A
T
G
G
A
G
A
C
G
7150 |
var(7104):[G:0.45]
|
var(7150):[A:0.03]
G
G
C
C
C
T
T
T
A
T
G
C
G
C
G
T
A
A
G
T
G
A
A
T
A
C
T
T
G
C
G
T
T
T
T
G
T
T
T
A
C
A
A
G
T
T
T
A
C
T
7200 |
var(7163):[A:0.01]
G
A
C
C
C
C
A
G
T
T
T
C
T
G
T
G
G
G
G
T
T
T
G
T
A
T
A
T
G
A
T
G
G
C
A
T
T
A
G
G
G
G
T
T
C
A
C
C
A
A
7250
A
T
T
T
G
G
A
C
T
T
C
A
A
A
T
A
A
G
A
A
G
T
C
A
T
A
G
G
G
C
A
A
G
A
A
C
T
C
T
G
G
G
T
C
A
T
A
A
C
A
7300
T
A
T
T
T
G
G
G
G
C
T
G
C
C
C
G
T
T
T
C
C
A
G
G
A
T
C
A
C
A
G
A
C
T
G
A
G
T
A
A
T
T
A
G
T
C
T
G
G
T
7350
T
A
T
A
A
A
C
A
A
C
A
A
G
T
T
C
C
T
G
T
A
T
G
A
G
T
C
C
C
T
G
T
A
C
A
C
T
C
A
T
A
G
T
A
G
G
T
C
T
G
7400
G
T
A
T
A
A
C
A
G
A
G
T
T
T
T
A
G
T
C
A
C
A
C
C
T
T
T
T
C
C
A
G
A
C
C
A
G
G
C
T
T
C
T
A
T
C
A
T
A
C
7450
A
G
T
G
A
T
G
A
C
A
G
T
C
A
T
C
C
T
G
G
T
C
C
C
C
T
T
T
T
A
T
A
A
C
C
A
T
A
G
G
T
G
A
A
A
G
T
G
T
C
7500
A
G
T
G
G
C
T
T
C
A
G
T
A
T
T
A
C
T
A
A
T
A
T
G
A
T
T
A
A
A
C
T
T
A
T
A
C
T
A
T
G
C
A
T
G
G
G
C
A
C
7550
C
T
T
T
C
T
G
G
G
C
A
A
C
A
A
G
C
T
T
G
G
C
A
G
C
A
T
T
T
G
C
A
A
A
G
A
T
A
A
C
A
T
G
A
C
A
G
C
A
A
7600
A
A
T
A
A
T
T
A
C
T
A
C
A
A
G
T
A
A
G
A
G
T
A
T
A
A
C
T
A
T
G
T
T
T
G
T
A
A
A
T
T
T
A
G
T
C
T
A
C
A
7650
T
T
T
A
C
T
T
A
T
G
T
A
T
C
A
T
T
G
A
C
T
T
C
C
T
C
A
G
G
C
T
T
C
A
G
C
C
A
T
G
C
A
T
A
G
A
C
T
A
G
7700
T
C
A
G
C
T
T
C
C
A
T
T
T
G
T
G
T
G
A
C
T
A
G
A
A
C
A
G
G
G
C
T
C
G
A
T
G
T
T
T
C
C
T
C
A
A
G
C
T
T
7750
C
A
G
C
C
G
T
G
C
G
T
G
G
A
C
C
A
A
C
C
A
G
C
C
T
C
T
G
G
T
G
T
G
G
T
T
G
A
A
G
C
A
G
G
G
C
A
G
T
T
7800
G
T
C
C
T
T
G
T
C
A
G
C
A
G
T
G
G
C
T
T
G
G
T
T
T
C
A
C
C
A
C
A
G
G
A
T
C
A
G
C
C
A
T
G
T
T
G
A
G
T
7850
G
G
T
C
T
G
G
G
T
T
T
T
G
T
T
G
A
C
T
T
G
T
C
C
A
C
T
G
G
T
C
C
T
G
G
G
T
G
G
T
G
G
C
T
G
C
T
T
C
T
7900
G
G
T
T
T
C
A
G
C
C
G
G
C
T
A
T
G
A
T
G
A
A
C
C
C
A
A
G
G
T
A
T
G
A
T
A
C
C
T
G
C
A
A
C
T
T
T
A
A
C
7950
A
G
C
A
G
T
G
G
G
A
G
T
A
G
A
C
A
A
G
A
T
C
A
C
A
A
T
A
T
G
G
G
G
A
C
T
A
T
C
C
C
A
T
A
A
A
G
G
C
C
8000
C
T
A
A
A
G
T
G
G
T
T
G
G
G
T
T
C
C
A
T
T
G
T
T
T
G
A
C
C
C
A
G
A
C
A
G
A
G
T
C
T
C
C
A
G
G
T
T
A
G
8050
A
A
G
G
G
T
T
G
T
A
C
T
G
C
A
T
C
T
G
T
G
A
G
G
C
T
A
A
C
A
G
G
T
A
T
T
C
T
T
T
C
T
C
T
T
A
C
C
C
A
8100
T
C
C
T
T
G
C
A
T
T
T
C
C
T
G
C
G
A
G
A
C
C
T
C
A
C
C
T
A
A
G
G
C
T
T
G
C
A
T
T
T
G
C
C
T
T
C
T
T
A
8150 |
var(8122):[G:0.18]
A
G
G
T
T
A
A
T
T
C
C
C
C
A
A
T
T
T
T
T
T
A
A
A
T
C
C
C
C
G
T
T
T
A
T
C
T
G
A
G
T
T
A
T
G
A
T
C
A
G
8200 |
var(8164):[G:0.01]
G
G
T
G
T
C
G
G
C
C
A
A
A
C
A
C
T
A
T
C
T
T
A
T
A
G
G
G
T
G
A
A
T
A
C
C
C
A
G
T
T
A
A
T
T
T
A
G
T
A
8250
G
G
G
G
T
G
C
A
C
C
T
G
A
C
T
C
A
G
A
G
A
A
G
G
A
C
C
A
T
G
G
G
C
A
G
C
A
C
C
T
G
A
T
C
C
C
A
T
C
T
8300
T
A
G
A
T
G
A
G
T
T
T
C
A
T
G
G
C
A
A
A
A
C
T
T
T
T
T
T
A
A
C
G
G
C
T
G
T
T
T
G
A
G
T
G
T
C
C
G
G
T
8350
T
T
A
T
T
C
T
T
T
C
A
A
C
T
T
T
C
C
A
G
A
A
C
T
C
T
A
T
G
G
G
T
G
A
T
A
A
G
C
T
G
T
A
T
G
C
A
G
T
T
8400
T
T
C
A
T
T
T
G
A
T
T
T
T
T
A
A
C
C
T
C
T
G
T
G
T
T
A
G
C
T
G
T
T
G
T
A
C
T
A
T
T
T
C
T
G
C
C
A
C
A
8450
A
A
T
G
C
T
G
G
G
C
C
A
T
T
G
T
C
T
G
A
T
C
C
T
A
A
A
G
T
T
A
G
A
G
G
C
A
G
T
C
G
A
A
A
T
C
T
A
G
G
8500
A
A
T
A
A
T
G
T
C
C
T
T
T
A
G
T
A
A
G
A
T
T
C
T
G
G
T
T
A
C
T
T
C
C
C
G
A
G
C
T
T
T
C
T
T
T
G
T
C
C
8550 |
var(8526):[A:0.10]
T
G
G
T
G
G
G
A
A
A
T
G
C
C
T
C
A
A
C
C
C
A
C
C
C
T
G
A
G
A
A
A
G
T
G
C
A
G
A
C
A
A
A
C
A
C
T
A
G
C
8600
A
T
G
C
A
C
C
G
G
T
A
G
C
C
T
C
C
G
G
T
T
C
G
A
G
G
C
A
G
C
T
C
A
G
T
A
A
A
G
C
C
C
A
C
A
T
G
C
A
G
8650
G
T
T
T
T
C
A
C
A
G
G
G
T
G
T
A
G
C
T
C
C
A
G
T
T
T
C
T
T
G
A
A
T
C
C
C
T
G
G
G
G
G
C
C
A
T
G
T
T
G
8700
G
C
C
C
C
T
G
C
T
G
T
G
G
A
T
T
G
T
T
T
G
G
G
G
C
A
C
A
A
G
T
T
A
A
A
C
A
T
T
A
C
T
C
A
T
A
A
A
T
G
8750
G
C
T
C
G
A
G
T
G
A
T
G
G
C
A
G
T
T
A
G
G
C
T
C
A
G
C
A
A
T
A
G
A
A
A
T
G
C
C
A
T
C
C
T
A
C
A
A
G
A
8800
G
T
C
T
C
T
A
A
T
G
C
A
G
T
T
T
T
T
C
C
C
A
T
A
T
G
T
G
T
T
C
C
T
T
G
A
T
G
A
A
A
C
T
G
T
T
T
T
A
T
8850
G
A
A
C
C
A
G
G
G
G
C
T
A
T
T
G
C
T
T
C
T
G
G
G
A
T
A
G
C
T
G
G
C
G
A
G
C
C
T
C
C
C
A
T
T
T
G
A
G
A
8900
A
C
T
T
C
C
A
C
C
A
A
C
T
T
C
C
T
T
T
C
T
G
G
T
A
A
C
T
T
C
C
A
C
T
T
T
C
C
T
G
C
T
C
A
A
A
C
C
A
A
8950
G
C
C
T
T
T
T
C
A
T
T
A
G
A
G
G
A
G
T
A
G
T
T
A
G
G
G
G
G
T
T
C
T
G
T
A
A
G
A
G
G
A
A
G
C
T
C
C
A
A
9000
T
A
A
G
G
G
C
A
T
G
G
T
A
A
G
G
G
T
T
T
C
C
T
C
T
T
C
C
T
T
C
T
T
A
G
T
T
A
T
C
G
C
T
G
T
C
A
T
T
G
9050 |
var(9040):[T:0.02]
C
A
G
C
T
C
T
T
T
T
G
G
C
T
T
C
T
C
T
T
T
C
T
G
C
C
T
T
T
C
T
G
T
T
T
T
C
T
C
T
G
G
C
C
T
T
G
T
C
A
9100
T
G
T
C
C
T
C
C
T
G
T
T
T
G
A
T
G
C
C
C
T
T
T
G
C
A
A
T
G
G
A
T
G
A
C
T
G
C
T
A
C
T
T
C
T
T
T
T
G
G
9150
A
G
C
C
C
A
T
A
C
A
G
C
T
T
C
T
A
A
G
A
G
C
T
G
C
T
C
T
A
T
T
T
C
C
T
T
T
T
T
A
T
T
T
T
T
G
A
T
T
T
9200
C
C
T
T
T
C
C
T
T
C
A
G
T
A
G
T
T
A
A
C
A
A
T
C
C
T
C
T
T
T
C
C
T
T
A
T
A
T
A
T
G
G
C
T
C
C
A
T
G
G
9250
G
C
A
T
G
C
A
A
A
G
T
G
G
C
A
A
A
G
G
C
A
T
A
C
C
T
T
G
A
G
T
C
A
G
T
A
T
A
G
A
T
G
T
T
T
A
C
C
G
A
9300
C
T
T
T
C
T
T
T
G
G
C
C
A
A
A
A
G
C
A
A
C
A
C
C
C
T
A
G
T
G
A
C
A
G
C
T
A
T
T
A
T
C
T
C
A
G
C
T
C
T
9350
T
T
G
G
G
C
T
A
A
A
G
T
T
C
C
G
G
C
C
G
G
C
A
G
A
G
G
G
C
A
G
G
T
T
T
C
A
G
C
T
G
C
T
G
A
A
T
T
C
A
9400
G
T
G
T
T
A
C
C
A
C
T
G
C
A
T
A
T
C
C
A
G
C
C
C
A
A
C
T
G
A
T
A
A
A
C
C
T
T
T
A
G
A
T
A
T
G
A
A
G
C
9450
T
G
C
T
T
C
C
A
T
C
A
G
C
A
A
A
G
T
A
T
T
T
A
A
C
A
T
G
T
G
G
G
T
C
T
T
T
T
A
A
G
G
G
C
T
A
G
T
C
C
9500
T
T
T
A
A
G
T
C
T
T
T
T
C
A
G
C
T
T
G
A
G
A
A
A
A
C
T
T
C
A
T
C
C
A
C
A
G
T
T
T
C
C
A
C
A
C
A
A
C
A
9550
G
T
G
A
T
A
C
C
C
T
G
G
G
C
C
A
C
A
C
A
A
T
G
G
G
G
G
C
T
T
T
C
C
A
T
G
C
T
C
C
G
C
C
C
A
T
T
C
T
A
9600
T
C
A
G
C
A
G
C
A
G
T
G
T
G
G
C
C
G
G
A
T
T
T
A
G
A
G
T
A
T
T
C
A
T
A
G
T
C
T
C
C
A
A
G
G
T
T
A
G
G
9650
T
A
G
G
G
G
A
T
T
T
C
A
C
A
C
A
A
A
A
G
C
C
C
T
T
G
A
T
A
T
C
T
T
A
A
C
A
T
T
C
T
A
G
G
G
T
T
A
G
A
9700
A
A
G
C
C
A
G
C
A
A
T
G
T
C
C
C
C
T
C
T
G
C
T
C
C
A
T
C
A
G
A
G
T
G
A
C
A
A
C
C
G
T
G
T
G
G
G
G
C
A
9750 |
var(9731):[G:0.10]
|
var(9748):[A:0.09]
C
C
C
A
A
A
T
T
A
T
T
A
C
C
A
T
T
C
C
T
C
T
G
T
T
G
T
T
G
G
G
A
C
A
G
T
A
A
G
G
G
T
C
T
T
T
A
T
C
A
9800 |
REPEAT
T
G
G
C
T
T
T
T
C
T
T
T
G
A
C
C
T
A
G
A
T
T
T
A
G
A
G
T
C
A
T
G
T
G
C
C
C
T
T
C
T
G
G
T
A
T
A
A
A
G
9850
G
A
G
A
T
T
T
G
T
G
C
T
T
G
C
A
A
T
T
T
C
T
G
G
A
G
G
A
A
A
T
C
T
C
T
T
C
C
T
A
A
C
A
A
G
G
G
C
A
C
9900
C
G
G
A
A
A
A
T
T
T
G
G
C
A
T
T
C
A
T
T
C
T
T
C
T
A
G
T
G
T
C
C
C
A
T
C
T
G
C
T
T
G
C
A
T
C
T
C
A
C
9950 |
REPEAT
A
C
A
T
T
G
A
T
C
T
C
C
C
T
T
A
A
G
C
C
T
A
A
G
T
T
G
G
C
C
C
T
C
T
T
G
T
C
C
T
G
G
C
T
T
A
G
C
T
T
10000
C
C
T
G
G
T
T
T
T
A
C
C
T
A
G
T
T
T
G
T
C
C
T
C
T
A
T
C
A
T
G
A
C
C
G
C
A
A
C
C
A
C
G
A
C
C
A
C
A
T
10050
C
C
T
C
T
C
A
C
A
A
A
A
C
C
A
G
T
T
T
C
T
C
T
T
C
C
A
A
C
T
A
A
G
G
C
C
A
C
C
G
C
C
A
G
C
A
A
G
T
C
10100
T
G
C
C
T
T
T
T
C
C
T
T
A
G
C
T
C
T
G
C
A
T
C
T
A
G
C
T
T
T
T
C
T
C
T
T
G
G
C
C
T
C
C
T
C
C
T
T
C
T
10150 |
var(10113):[T:0.03]
G
A
T
T
T
A
C
A
A
A
C
A
C
C
T
T
A
G
T
A
G
C
C
A
C
C
T
G
G
A
T
A
A
G
C
T
G
G
G
T
A
A
T
A
T
T
C
A
C
A
10200
C
C
T
T
C
A
A
A
C
C
C
T
T
C
T
A
A
C
T
T
C
C
G
A
T
G
T
C
T
T
C
T
T
G
C
A
C
C
T
G
G
C
T
T
A
C
A
A
A
T
10250
G
C
C
A
C
A
T
T
A
A
C
C
A
T
A
C
A
C
T
G
A
T
T
A
C
C
C
G
C
A
G
C
C
T
C
T
G
G
G
T
C
A
A
G
T
G
G
C
A
T
10300
G
T
A
A
A
G
C
T
G
G
T
A
A
G
C
C
T
C
G
C
A
C
A
G
C
C
T
C
T
C
A
T
A
A
A
A
T
T
C
A
C
C
G
G
G
A
C
T
T
T
10350
T
A
T
C
T
G
G
C
T
T
C
T
G
G
C
G
A
A
C
C
T
C
T
G
A
G
A
C
C
T
T
T
C
C
G
A
T
A
T
T
G
G
T
G
G
C
C
T
T
T
10400
T
T
C
T
C
T
C
C
A
G
C
G
T
T
T
A
T
T
C
C
A
T
T
T
A
G
G
A
G
T
G
C
C
T
C
T
C
A
A
T
A
C
T
G
C
T
G
C
A
A
10450
A
C
T
T
G
T
A
G
C
C
C
T
T
G
A
G
C
C
T
G
G
T
T
A
G
G
G
T
C
C
C
A
G
C
C
T
G
G
G
T
C
A
G
C
C
T
C
T
A
T
10500
C
A
G
G
A
G
T
G
C
T
T
G
T
T
G
T
G
T
A
T
A
C
T
G
C
C
T
G
A
T
A
T
C
T
C
C
T
G
T
G
C
T
T
G
A
A
G
A
T
G
10550
C
A
T
T
T
T
T
C
T
C
C
A
G
C
C
A
C
T
G
G
A
G
A
G
C
A
G
C
T
T
G
T
A
T
A
A
C
T
C
T
A
C
G
G
T
G
C
T
C
T
10600 |
var(10593):[A:0.03]
T
C
C
A
T
A
T
T
A
A
A
T
A
A
T
G
A
C
A
G
A
A
A
A
A
A
A
T
G
T
T
T
A
C
A
A
T
C
A
A
C
C
C
A
G
G
T
A
G
G
10650 |
var(10621):[:0.09]
A
T
T
G
T
G
A
G
T
T
A
G
G
A
A
A
A
T
G
G
A
C
T
G
C
A
T
T
A
G
A
T
C
T
A
T
A
A
G
A
G
C
C
T
G
A
G
G
C
T
10700 |
var(10666):[G:0.01]
T
C
T
C
T
C
T
A
T
A
G
G
A
G
G
G
A
G
T
A
T
G
T
T
G
T
C
T
C
C
A
A
T
T
T
A
A
G
A
G
A
T
C
A
G
T
A
G
T
A
10750 |
var(10718):[A:0.01]
G
A
G
A
A
G
G
G
C
T
G
A
T
A
A
A
A
G
A
A
G
A
G
C
T
G
T
T
C
T
C
C
C
C
C
T
T
G
G
A
C
T
T
C
A
T
T
C
T
G
10800
T
G
C
A
T
T
C
A
A
A
T
A
A
A
T
T
T
G
T
C
C
C
C
A
T
G
T
T
T
C
T
C
A
G
A
G
T
G
G
C
A
T
C
T
G
C
A
T
T
G
10850
C
T
T
G
G
G
C
A
C
G
G
A
C
C
G
A
C
C
T
A
A
G
G
C
G
G
C
C
G
A
C
C
T
C
A
T
C
A
C
C
C
T
G
G
A
G
T
T
C
C
10900 |
var(10861):[A:0.02]
|
var(10875):[A:0.19]
|
var(10879):[A:0.01]
T
C
C
C
T
T
G
G
C
T
T
T
T
C
A
G
T
C
A
A
G
G
G
C
T
C
T
G
G
C
T
C
C
T
C
T
C
T
G
C
G
T
G
G
T
G
T
T
G
C
10950
C
T
G
A
G
G
G
G
T
G
C
T
T
C
C
T
T
C
T
G
A
G
T
C
T
G
A
G
T
C
T
C
C
G
G
A
G
G
C
A
G
C
C
G
G
G
G
C
A
G
11000
C
C
T
T
C
T
G
T
C
T
A
A
G
C
T
T
T
G
C
C
A
G
A
G
G
T
G
G
A
T
A
A
A
T
T
G
G
T
G
C
A
T
A
G
T
G
G
G
G
T
11050
G
G
A
A
T
T
T
C
T
A
A
C
T
C
T
T
C
A
G
G
C
G
G
G
G
C
C
T
G
T
A
G
G
A
C
A
G
G
T
T
T
T
T
A
C
T
G
C
T
T
11100 |
var(11071):[T:0.10]
T
T
C
C
T
G
T
G
A
C
T
T
T
T
C
T
T
T
T
T
C
T
G
A
T
G
C
C
T
T
G
C
A
G
T
T
T
C
T
T
T
C
T
A
T
T
G
T
T
C
11150
C
T
G
G
T
T
T
T
G
T
C
T
T
G
G
C
C
G
T
T
A
G
A
G
T
C
T
T
A
C
A
G
T
A
G
A
T
C
T
C
A
A
A
G
T
A
G
G
C
C
11200
T
G
C
A
G
C
C
A
C
T
T
A
G
G
G
A
G
G
G
T
C
T
G
A
A
T
T
A
T
A
C
T
T
A
G
C
C
A
G
G
A
G
T
C
A
A
T
A
T
A
11250
C
G
G
A
A
A
C
T
G
A
T
C
C
A
G
G
T
G
C
C
C
G
G
G
C
T
G
T
T
C
T
C
C
A
A
G
C
C
T
G
G
T
G
A
C
C
A
C
C
C
11300 |
var(11271):[T:0.02]
|
var(11272):[A:0.02]
G
A
A
A
C
A
C
T
C
G
G
C
C
A
A
T
T
A
T
C
T
C
C
C
T
G
T
C
T
A
T
T
G
T
C
C
C
C
T
T
G
G
C
T
G
G
C
C
A
C
11350
C
C
T
A
C
A
T
T
A
A
A
A
G
A
T
G
G
C
T
A
T
T
T
T
A
T
C
T
C
A
A
A
A
A
A
G
T
T
C
T
C
A
G
T
T
T
C
T
G
T
11400
G
A
A
G
T
T
A
G
C
T
T
A
A
C
C
C
C
A
T
A
G
T
C
A
C
C
A
T
T
A
A
A
A
C
T
T
T
T
T
T
T
A
A
A
G
T
T
T
T
T
11450
C
A
G
C
A
C
G
C
A
C
T
C
C
A
G
T
G
G
A
A
T
A
G
G
C
T
T
T
G
A
C
G
C
T
T
T
T
C
C
T
C
C
T
G
T
T
T
C
C
T
11500
C
C
C
T
T
G
T
G
A
T
G
C
A
C
T
T
T
C
A
C
T
C
T
C
A
C
T
T
T
C
A
C
T
C
T
T
G
G
A
T
C
C
A
C
C
A
G
A
C
T
11550 |
var(11510):[C:0.10]
G
G
G
T
C
C
T
A
T
T
A
C
A
G
G
A
G
G
T
T
C
G
G
A
C
A
C
T
G
C
T
T
A
G
C
C
A
G
G
A
G
C
A
T
G
C
C
T
T
A
11600
A
T
T
C
C
T
G
T
C
A
C
A
G
C
T
A
G
C
T
G
C
A
G
C
T
G
T
G
G
A
G
C
T
G
G
T
C
C
T
C
T
G
G
G
C
C
G
T
A
T
11650
G
C
A
G
T
G
T
C
C
T
A
G
G
T
C
T
G
G
T
T
T
T
T
C
C
C
A
C
A
C
T
C
G
C
C
T
G
G
G
A
G
C
A
C
A
C
A
G
T
C
11700
C
A
C
G
C
T
A
A
G
A
G
A
T
C
T
G
T
G
C
C
T
C
C
C
C
A
C
A
T
C
A
A
C
C
C
C
G
C
C
T
T
G
G
T
C
T
C
T
C
C
11750 |
var(11736):[T:0.01]
C
G
A
G
A
C
C
A
T
C
T
C
T
T
T
T
A
C
A
C
A
C
T
T
T
C
A
C
A
C
A
C
C
T
C
C
C
C
C
A
T
C
C
C
C
A
A
A
A
T
11800 |
var(11751):[T:0.17]
G
G
T
T
T
T
C
C
T
T
T
C
T
G
A
C
C
G
A
C
T
C
A
T
G
A
G
C
C
C
C
A
C
T
T
A
C
G
T
C
T
G
G
T
G
T
C
A
A
T
11850 |
var(11837):[T:0.17]
T
A
G
G
G
T
G
T
G
A
G
T
T
T
C
A
T
C
T
G
A
A
T
C
A
A
T
G
G
G
C
C
T
C
T
C
C
C
A
T
T
G
T
C
C
C
A
A
C
C
11900
C
C
C
T
C
G
G
G
T
C
A
G
A
C
T
A
G
T
T
G
T
C
A
T
G
C
C
C
T
T
G
G
A
G
G
T
G
A
C
C
A
G
G
C
T
C
C
C
C
T
11950
T
C
C
A
T
C
C
T
T
A
T
G
G
G
A
C
G
G
G
T
C
T
T
G
C
C
T
T
A
G
G
G
C
C
C
A
A
A
C
C
T
T
A
C
T
G
C
A
G
T
12000
T
C
A
T
A
T
G
T
C
T
A
T
G
C
A
C
T
G
T
T
C
T
T
G
T
G
A
C
T
G
T
C
C
T
G
C
A
A
C
C
C
T
T
T
C
C
A
C
T
G
12050 |
var(12022):[C:0.10]
G
T
T
C
C
A
T
T
T
G
C
A
C
T
G
T
T
G
G
A
G
G
A
A
G
G
C
T
C
C
A
G
A
A
C
G
T
G
G
A
A
G
G
G
C
T
G
T
T
C
12100
T
C
C
T
T
C
T
G
G
G
C
T
A
A
A
A
C
T
C
T
C
C
C
G
G
T
G
G
C
A
C
C
A
A
G
G
A
C
C
C
C
A
G
A
T
T
T
C
C
C
12150 |
var(12138):[T:0.10]
A
T
G
T
C
C
T
G
G
G
G
C
T
C
T
A
A
C
C
C
A
C
A
G
G
C
A
A
A
G
G
A
G
A
C
G
A
A
A
A
T
C
T
G
C
C
A
T
C
T
12200
C
C
A
A
T
C
C
C
A
G
A
C
T
G
G
T
C
C
C
C
G
G
A
A
A
T
G
T
T
G
T
G
G
G
A
C
A
A
C
C
A
A
A
G
A
T
T
G
G
A
12250 |
var(12216):[C:0.10]
|
REPEAT
G
A
G
A
C
C
G
A
A
A
A
A
G
G
T
T
C
A
G
G
A
G
A
G
T
T
T
A
C
T
A
A
A
T
T
A
A
G
G
T
G
A
T
C
A
G
T
A
G
C
12300
A
C
A
T
A
T
G
T
C
C
A
G
A
A
A
G
T
C
T
G
A
G
C
C
C
T
G
A
G
C
A
A
A
G
G
G
C
T
T
T
T
C
C
T
A
C
G
T
T
T
12350 |
var(12347):[A:0.01]
A
A
A
C
A
T
C
T
T
A
A
G
G
T
G
G
G
A
A
C
T
A
C
A
T
G
A
G
G
C
A
G
G
A
A
G
C
G
A
G
A
T
A
C
A
G
A
A
G
C
12400
A
A
G
A
A
A
C
A
A
A
G
G
C
A
G
C
A
T
T
A
C
A
A
C
A
T
T
T
G
T
T
A
T
A
T
T
T
T
G
A
G
A
A
A
G
A
C
A
T
G
12450
T
C
T
T
G
C
A
A
C
C
T
A
A
A
C
T
T
A
T
C
A
G
T
C
T
T
G
T
G
A
C
C
C
T
G
C
A
G
T
C
A
T
G
C
A
G
G
A
A
C
12500 |
var(12473):[C:0.02]
T
C
A
C
T
G
G
G
C
C
T
G
T
A
A
T
A
A
A
C
T
C
T
G
A
G
G
A
A
T
G
T
G
G
A
T
T
T
G
G
G
A
A
G
T
A
T
A
G
A
12550
T
A
A
G
G
T
C
C
A
C
T
G
T
C
C
A
C
A
G
A
G
A
G
A
A
G
A
C
A
G
G
C
T
G
T
T
A
A
T
A
T
T
C
C
C
T
T
T
T
A
12600
A
C
T
T
G
A
G
T
G
T
A
A
G
G
T
G
G
G
G
G
G
TCACACTTT GCAGCAACTT TAAGAGGATT
12650
TTAAAATTTC TATTACTACT ACTACTATTA GGTTATAGTT GATTTCCTTA
12700
ATTCCTTCTT CA
G
G
T
C
T
A
C
A
G
G
G
T
A
A
T
G
G
C
A
T
G
A
G
G
G
T
C
C
A
C
C
A
T
C
T
T
G
T
12750 |
REPEAT
C
T
T
G
C
C
A
C
T
G
T
C
C
A
G
G
A
C
A
C
A
C
A
C
A
T
G
G
C
T
C
T
G
T
T
C
A
T
A
A
G
T
C
C
C
T
A
C
G
A
12800
A
A
T
G
T
T
T
C
T
T
T
C
T
G
A
G
A
A
A
C
T
G
G
A
T
A
T
G
T
C
A
G
C
C
T
T
T
T
T
C
T
T
T
G
A
C
C
T
C
T
12850
C
A
G
C
T
T
C
C
T
T
G
G
A
C
T
T
T
A
A
G
G
G
T
A
G
G
T
T
T
G
C
A
C
A
G
A
C
C
T
G
T
T
C
A
C
T
A
T
G
G
12900 |
var(12891):[C:0.08]
A
A
C
A
TGACTT TTTTGTTCTT TCATGTATAA TTTTAGTATC TC
T
AAACAC
G
12950 |
var(12943):[C:0.01]
|
var(12950):[A:0.08]
TGTAGTAAAA AAAAATGGTA AGAAGAATGA TATAATGAAT CATAGACAGA
13000
GAACAGATGA CCTGCTTCAA TCAGATTTCA AAGACAATGT GAAAAAGATC
13050
TAATGTAGCT CAAAAGGAGT GTCTTCCCCA TTCATCTTTT TAAGGAATCA
13100
TGTGGTTTGA CAGGCTCAAA ATCTTTCTCC AGCTCACTGG AAACTGGGTG
13150
TGAAAATGGA AGAGGAAGAG GCATTAGCTA AATGGAGCCC AGGACCACTA
13200
TGGAGTGGGA AAGGCTGAAG AGTACGGCAG GGAGCCCCGT GGAGAGCCAG
13250
ATGCAGTGGA AGGGTATGGG GCATAGCAGG GAGATTAATT GGGGACCTAC
13300
CAAAAAGAGA GGAAAAGAGT GAATCAACGA TAGACCCCTC TTGCTTTGAA
13350
CCACTGCCAG GGGCCCCGAT AGCTGCAAAT GCCAAGCACA TTACTCAAAA
13400
TCACCCTGGC AGCCAAGTCC TAGTCCTTGG CAGCCTCTCC GCCTCCTGGG
13450
GCCAGATTCC CTTAAGGCCC C
A
CTAGTTGT TTCATTCACT CACCTGCTTG
13500 |
var(13472):[G:0.19]
CCACTTGCAC AATCCCTGCA CTGCCCTGCC CTTCAGATCT GCCCATCCTC
13550
AGTGTTTTAC CTTTCTGCAG CTAATGAAGC CCCAACAAAA AACGAGCTTC
13600
CCAATAAAAC GAGCTTCCAC ATAAAAGTGA CAGCAAATGT TTTTTGAAGT
13650
GATTTTTATA CTTTCATATT TTTCCTAAAA TAAAATAATA TAATGTAGTA
13700
TCAAAATAAA ATTGTAGTTG CTTCAAGGAA CCATCTGCCT TAAACCC
G
GG
13750 |
var(13748):[A:0.17]
AGTGATTGTC TGTTTGTGGA TTTTACAG
T
T
T
C
C
T
C
T
T
T
G
G
T
C
C
T
G
A
G
C
T
G
13800 | Exon 2 |
UTR
G
T
T
A
A
A
A
G
G
A
A
C
A
C
T
G
G
T
T
G
C
C
T
G
A
A
C
A
G
T
C
A
C
A
C
T
T
G
C
A
A
C
C
A
T
G
A
T
G
C
13850
M M 2
C
T
A
A
A
C
A
T
T
G
C
T
T
T
C
T
A
G
G
C
T
T
C
C
T
C
A
T
C
A
G
T
T
T
C
T
T
C
C
T
T
A
C
T
G
G
T
G
T
A
13900 |
var(13890):[C:0.02]
P K H C F L G F L I S F F L T G V 19
G
C
A
G
GTAAGT GCTTTGTTTC TTTTTAATTG CTCA
T
AGCTT TGTCATCTGA
13950 |
var(13935):[C:0.02]
A 20
GTCCAATCAA GGATCTGTTG GAAATGGCAC TGGTGCTTTT TTGAACTTTA
14000
TAAAGGCTGC AGCTTTTGAT GTCACTAAAT GAT
C
A
G
A
G
C
A
G
G
C
A
T
G
G
G
G
T
14050 |
NOT SCANNED
T
A
G
T
G
T
C
T
A
T
C
T
G
C
A
G
C
T
T
G
A
A
T
G
A
C
C
C
C
A
C
A
T
G
T
A
C
T
T
A
A
T
G
A
G
T
T
C
C
C
14100
A
C
T
A
A
A
G
A
A
A
A
G
G
C
T
C
T
C
T
A
G
A
G
G
G
T
G
C
A
G
A
G
A
C
T
T
C
A
T
A
C
A
G
A
A
C
A
A
A
T
14150
G
T
A
C
A
T
C
C
A
T
T
T
C
T
C
T
CTCT CTCTCTCCTT CCCTCCCTCC CTCTTTCTTT
14200
CTCTCCCTCT CTCTTTCTCT CTGGCTCTCA CTCACCTTAG AATGTCTTTT
14250
ACCTTGAAGG A
A
C
A
C
T
A
A
A
T
C
A
T
G
G
T
G
G
T
T
A
C
C
A
G
C
A
C
A
G
G
C
T
C
C
T
A
A
G
C
14300 |
REPEAT
C
A
A
G
C
T
A
T
C
A
T
G
G
T
C
T
G
G
A
T
T
T
C
A
G
A
T
C
T
G
C
C
A
T
T
T
A
C
C
A
T
C
T
A
G
G
A
A
A
A
14350
C
T
T
G
G
G
A
A
A
T
T
T
A
C
T
T
A
A
C
A
C
C
C
T
C
A
A
T
T
T
C
C
T
C
A
T
T
A
G
T
A
G
A
A
T
G
G
G
G
A
14400
T
T
C
T
A
G
G
T
C
A
C
T
G
T
G
A
A
G
A
T
T
A
A
A
T
C
A
A
T
T
A
A
T
A
T
A
T
G
C
C
A
A
A
T
G
C
T
T
A
G
14450
A
G
A
A
G
T
G
C
C
T
G
G
C
A
C
A
GGAT AGGGACCACA AACAACAGGT GAGAATTTGC
14500
TTCTGGTATT CGTGGAGGAA ACTGCAGGAG TGTAGAGCAT CTTATCAGCA
14550
CCACATACTT CTGAGCAAGC CTGTAAGAAT GCAAGTTAAC AAATGGGTAC
14600
CTCTCAGTGT AAGT
G
ATTTA AGTAACTTGC CAAGATGGTG CAGTTGTCCA
14650 |
var(14615):[A:0.01]
GTGACTAATA CATAAAAGCA ATTCAAGCCT TCATCTTCCA GAAGTGTTTG
14700
GATTTGAGAA GACTCTGGTA CTTGGTAACA GCAAGGGCAC ATTTAGCAAA
14750
ATACGGCAGG AATTCAAATG CTACCAAAAT GT
T
C
C
T
G
G
C
T
C
T
G
C
A
T
C
T
T
A
14800 |
REPEAT
C
C
A
A
A
C
C
T
G
T
A
A
C
C
T
C
G
A
G
T
A
A
G
A
G
A
T
G
C
A
A
C
T
T
T
C
T
A
A
A
G
C
C
T
C
A
G
C
T
T
14850 |
var(14836):[T:0.10]
C
C
T
C
A
T
C
T
G
T
A
G
A
A
T
G
C
G
A
T
A
A
T
A
A
A
A
A
T
A
T
T
T
A
C
C
T
T
A
C
T
T
G
G
T
G
G
C
T
G
14900
T
G
G
G
A
A
T
T
A
A
G
T
A
A
G
T
T
G
T
A
A
A
G
C
T
T
T
G
A
A
C
A
T
A
G
T
G
C
C
T
A
A
C
A
T
A
A
G
T
T
14950
A
A
T
G
T
T
C
A
T
A
T
A
T
G
T
T
CAAT GTTTGATGAA TGCCGGCCAG AAGGAGGAGG
15000
AGGAGGGAAG AAGGAAGAAG ATAAAGTATA GCCTCAGCTT CTAATTGGTC
15050
TGCCTCTTTC ATTAGCTCCT CTCTCCCATG GCTTTGCTCT TGGTTTTCTG
15100
TTGGA
G
G
G
T
A
A
T
G
G
C
A
G
G
C
T
C
T
G
C
A
C
T
C
A
G
A
C
T
G
T
C
T
G
G
G
T
A
C
A
A
A
A
T
C
A
15150 |
REPEAT
G
C
T
T
C
A
C
C
A
T
T
G
G
C
T
G
C
C
T
G
G
C
A
A
T
C
T
C
C
T
T
C
A
G
G
T
G
T
C
C
A
A
G
G
C
T
T
C
G
T
15200
T
T
T
T
T
C
A
G
T
C
T
G
T
A
A
G
A
G
G
A
A
G
A
C
C
A
T
A
A
T
G
C
A
C
A
G
T
A
C
C
T
T
C
C
T
C
A
C
A
G
15250
A
A
G
A
G
C
T
G
G
G
C
A
A
A
T
T
A
A
A
T
G
A
G
T
G
A
A
T
G
C
A
G
A
T
A
A
A
A
G
T
C
C
C
T
C
A
G
T
G
C
15300
C
T
G
G
T
G
C
A
GT GTTATTACTG TTGGTGGTGG TAGCACTGAT GTTACAAAAA
15350
TGAGAGAAGA AATCCATAGA CAGAGAGATT AAGGGCATTA AGCCATCTAT
15400
CTTCATGTTA GCAAATCAAT TCTAGGCAGG CCTTCAGGAA ATTGTGCCTG
15450
TCATCTCCTG AAAACTTCTG GAATGTTTAT GTTCTAAAGA TGACTGATCA
15500
GGCAGTGATT TTTGTGAGCA AAATCA
A
CTG TGGCTGTAGA CTCTTTCCAA
15550 |
var(15527):[G:0.03]
GAACACAACA CCATTTGATG CACTGATGGT GGTCCAAACA ATAAAAGTGA
15600
AAACAAATTA AAAAACAAAT AACAGTATTC ACACTATTTG GTTGGTAAGA
15650
AGAAAGGCCT GAGGAAACAG TCTTGTTCAT TTGAAAATAA CAAGTCTTGA
15700
AAGTTCAGAG CTGAGACCAT GGGCTTGGAA GTGTTTTTTT AACCATCTCA
15750
ATAACGTGAT
A
C
A
T
T
T
G
A
G
C
A
A
A
G
A
C
T
T
G
A
A
G
G
A
G
G
T
G
G
A
G
A
A
A
T
G
A
G
C
C
15800 |
REPEAT
A
T
G
T
G
A
A
A
T
C
C
A
G
G
G
G
A
A
G
A
G
C
A
G
A
C
C
A
G
G
A
A
A
A
G
G
G
A
A
G
G
G
C
C
A
G
T
G
C
A
15850
G
A
G
G
C
C
C
T
A
A
G
G
C
A
G
A
G
T
C
A
C
T
G
G
A
G
T
C
A
T
G
G
T
G
G
A
G
C
A
A
G
T
G
A
A
G
G
A
G
T
15900
C
A
A
C
A
C
T
G
C
A
A
A
C
A
C
A
G
G
G
G
T
C
G
G
G
G
T
G
A
C
A
G
A
A
G
A
T
G
A
G
G
T
C
A
G
G
G
A
G
A
15950
A
A
A
C
A
G
A
A
G
A
TATGCTTCCT
G
G
C
C
G
G
G
T
G
C
A
G
T
G
G
C
T
C
A
C
G
C
C
T
G
T
A
A
T
C
16000 |
var(15956):[A:0.10]
|
REPEAT
|
var(15981):[G:0.12]
C
C
A
G
C
A
C
T
T
T
G
G
G
A
G
G
C
C
G
A
G
G
T
G
G
G
C
G
G
A
T
C
A
C
T
T
G
A
G
G
T
C
A
G
G
A
G
T
T
C
16050 |
var(16026):[A:0.18]
G
A
G
A
C
C
A
G
C
C
T
G
C
C
C
A
A
C
A
T
G
G
C
A
A
A
A
C
C
C
C
A
T
C
T
C
T
A
C
T
A
A
A
A
A
T
A
C
A
A
16100
A
A
A
A
A
T
T
A
G
C
C
A
G
G
C
A
T
G
G
T
G
G
C
G
G
G
C
A
C
C
T
G
T
A
A
T
C
C
C
A
G
C
T
A
C
T
C
A
G
G
16150
A
G
G
C
T
G
A
G
G
C
A
G
G
A
G
A
A
T
C
G
C
T
T
G
A
A
T
C
C
G
G
G
A
G
G
C
A
G
A
G
G
T
T
G
C
A
G
T
G
A
16200
G
C
T
G
A
G
A
T
C
A
C
G
C
C
A
C
T
G
C
A
C
T
C
C
A
G
C
C
A
G
G
G
C
G
A
C
A
A
G
A
G
T
G
A
A
A
C
T
C
C
16250
A
T
C
C
A
A
A
A
A
A
A
A
A
A
GATATG CTTCCTGACT CCTCCTTCTG CCCAACTTCT
16300
TATCCCTTAT AAAAAACCTT GAACCCTAAG TAAAATTTTG CCAAAATTCT
16350
CTTGCCTCCA TGCAACTAAA GGCAAG
C
AAG GTTGTACCAC CTATGTTGCC
16400 |
var(16377):[A:0.01]
TGATTTGAGG AAGAAAGCAC AAGTCATGCC AGTGCAAAAT TATCCCATGC
16450
CATGCCATGA TTAGTCTCAG AAACACTACC CCCCAGCAGG GTCTTGGGCA
16500
GTTTTCCTCA TTAGCATGAC CATTTCATCT GAGGGATTAT GCTTGGATAC
16550
TTGGAGCCAG GATGCAGGCA GGTAAATACA GCCATTCAGG AGTGGGACAG
16600
CAAAGGCAGA CCTACCTGGA AGCAGGACCC AGAGATTGAG CAAGAACCTG
16650
CGAAAGGAGG GACTGAGTGC TGGGCTGAGG TCCTGGAGCC CAGAAGTGGT
16700
CACTAGCAAA TTTTGCTTGA GTAGTACCAA TATAGTGATT CCTAAGAAGA
16750
TGGTTGGTGG TCTTAGTGTG GGTCTTTCAT CTCAGTCATT ATATTCCATC
16800
ACTATTTGGG AA
C
AAAATAA GAGCAATATT TTTTTTA
A
TG CAATTTACTT
16850 |
var(16813):[T:0.04]
|
var(16838):[C:0.10]
CCCCCACAGC CTGGGAAATA GGGTGGGAAG GTATCACGTA CATGTTTATG
16900
ATCTGGAACT CATTA
T
T
C
T
G
A
G
A
C
T
T
T
A
G
C
G
T
G
C
A
T
C
A
A
A
A
T
C
A
T
T
G
C
A
T
16950 |
REPEAT
T
G
A
A
G
A
T
T
C
A
A
A
A
T
G
T
T
G
A
T
T
T
C
T
G
G
G
C
T
C
C
A
C
C
T
C
T
A
CT ATCTGCACTT
17000
AGAGCAACTA CTTTAGGGAA TCCTGATGCA GGTATTCCAC TGAAAACTAC
17050
TGCTGGGAAC AGCAGTGCTC CAAGCAACGT TCAATGTTCT TCCTTCTCTT
17100
A
TTATCTTAG
G
A
A
C
T
C
A
G
T
C
A
A
C
G
C
A
T
G
A
G
T
C
T
C
T
G
A
A
G
C
C
T
C
A
G
A
G
G
G
T
17150 |
var(17101):[G:0.04]
| Exon 3
G T Q S T H E S L K P Q R V 34
A
C
A
A
T
T
T
C
A
G
T
C
C
C
G
A
A
A
T
T
T
T
C
A
C
A
A
C
A
T
T
T
T
G
C
A
A
T
G
G
C
A
G
C
C
T
G
G
G
A
17200
Q F Q S R N F H N I L Q W Q P G 50
G
G
G
C
A
C
T
T
A
C
T
G
G
C
A
A
C
A
G
C
A
G
T
G
T
C
T
A
T
T
T
T
G
T
G
C
A
G
T
A
C
A
A
A
A
T
GTAA
17250
R A L T G N S S V Y F V Q Y K I 66
GTAAATTGAG CCTCCTTCAG CTGATAGAGA TGGCACTGGG ATAACATGTT
17300
CTAGAATGCA ATGGAGTGTT AGGATCCGAG CTTTTTTTCA GTTTCAGAGG
17350
GGTTGAGAAG AAGCCAAGGT CAGGATAACA GTGACTTGTC TCCCCTGAAG
17400
GCTGCCTGGG GACTCAAAAT GCATGATGGT ATGCAGTGCA CTGGGCAGAT
17450
ACTTCAGCCC TAGACCTGCA CCAAGACCTC ACAGGCTCAG CCTTTGCCTC
17500
CATGGAGGA
G
C
C
T
G
G
C
A
C
A
T
G
G
T
G
G
G
T
T
C
T
C
A
A
T
A
T
A
G
A
T
T
T
G
T
C
A
G
G
C
G
17550 |
REPEAT
A
A
T
G
TTGGAA GCAACTTATT AGCACATAGC GAGTACTCAG TGAGTGAAAC
17600
TATCGGTAGT TGAAAAAGAA GTTGTGGCAA ACATGGTGGT GAGTGTGTAA
17650
AATAAGGTTT TAATTTAAAA GTCACTTTCA GAGTGGATTT ACTATTTAGA
17700
AAATTCCTTT CAAAAACTAA TGACTCTCGT AAGCATGAAC ACAAACTGGA
17750
ACACGCTGCT GCATGTTCCT CTCGTGTGAT CCTCAGGCTA CTCCTGCTGG
17800
ATCATTGCCA AAACTCAGAT ATAATCTACT CCTTTCCTGG CTCAAGGCTT
17850
GGAAACAAAC ACTCTTGACT TGAAAATGTC AGGTTTTTCC ACTCATATAT
17900
TTCTG
G
GGGG GTGAGGGGGG TTGAGGCTCA ATCCTGTCTC CTGACAGTGA
17950 |
var(17906):[A:0.07]
GACAGGAGAT ATTACAGTTT AGCTTTCATG GTTTTTCAAT AGAAATTCAG
18000
GAAATCAAAT GCAGCTATGG CCAAAGTAGC AATTTTTATC CCATAAATTC
18050
ATCCATGTCT CTCCAGCATG GGGTAGGTCC TA
G
GTCAGAT TTTCCTGCTA
18100 |
var(18083):[A:0.02]
ATTAATTTCG GAAGGAATAT CCCCAGAAGC ATCT
C
C
A
T
C
T
T
TAACC
G
CTA
18150 |
var(18135):[:0.07]
|
var(18147):[A:0.06]
CGACTTCTCT CTACATATTT TATGTAGCGA TTGTAAAATG TACAAATCTT
18200
TACAATGAAG GTTTCTCCAT TACAAAAGTA GATTTGTGCA TTGCT
G
GAGA
18250 |
var(18246):[A:0.13]
TACTTTCAGC ATGCAGAAAG TAAAGATTGG TACTCTTTTT ATGCTTCCCC
18300
TGGAG
T
AGTA TAAATAGGTC AAAAGTGGAC CTATTTGTGG TCCAAAGTAC
18350 |
var(18306):[C:0.12]
TAAGAAGATT
A
G
A
A
A
C
T
G
T
T
T
T
A
C
C
A
T
G
A
A
T
C
T
A
A
T
G
A
A
G
A
T
T
A
A
A
C
T
T
C
18400 |
REPEAT
A
G
G
A
C
C
C
C
AA TGCAAGG
A
T
T
T
T
A
T
A
T
T
T
A
T
A
A
A
T
C
T
T
T
T
C
C
T
A
A
A
G
A
G
G
A
18450 |
REPEAT
C
T
C
C
C
A
A
G
C
T
G
C
T
A
T
G
G
T
T
T
G
A
G
T
T
T
G
T
C
T
C
C
A
C
C
A
A
A
A
T
T
C
A
T
G
T
T
G
A
A
18500 |
REPEAT
A
T
T
T
G
A
T
C
C
T
T
A
G
T
G
T
G
G
T
G
G
T
G
T
T
G
G
A
A
G
T
A
G
G
G
C
C
T
C
G
T
A
G
G
A
G
G
T
G
T
18550 |
var(18520):[A:0.01]
|
var(18540):[A:0.01]
T
T
G
G
G
T
C
A
T
G
G
G
G
A
T
G
G
A
G
C
A
C
T
C
A
T
G
A
A
T
G
G
C
T
T
G
G
T
A
C
C
A
T
T
A
T
T
G
C
T
18600
G
C
A
G
T
T
G
A
G
T
G
A
G
T
T
C
T
C
A
C
T
C
T
T
G
C
A
A
G
A
C
T
G
A
A
T
T
T
G
T
C
A
T
G
G
A
A
A
T
G
18650
T
T
T
C
T
A
T
G
A
G
A
G
T
G
G
T
T
G
T
T
G
T
A
A
A
G
C
C
A
G
G
A
T
G
C
C
C
C
T
T
G
A
G
T
T
T
G
G
C
C
18700
T
C
T
T
C
A
C
A
C
G
A
T
C
T
G
T
T
T
T
C
C
C
C
A
T
T
G
A
C
C
T
T
C
T
C
T
A
G
C
A
T
G
T
T
C
T
C
A
T
G
18750 | Exon 4
M F S C 70
C
A
G
C
A
T
G
A
A
A
A
G
C
T
C
T
C
A
C
C
A
G
A
A
G
C
C
A
A
G
T
G
G
A
T
G
C
T
G
G
C
A
G
C
A
C
A
T
T
T
18800
S M K S S H Q K P S G C W Q H I 86
C
T
T
G
T
A
A
C
T
T
C
C
C
A
G
G
C
T
G
C
A
G
A
A
C
A
T
T
G
G
C
T
A
A
G
T
A
C
A
C
C
T
C
T
T
T
T
C
C
T
18850
S C N F P G C R T L A K 98
T
A
T
C
A
A
T
T
A
C
C
T
A
G
C
C
T
C
A
G
G
T
G
T
T
C
T
G
T
T
A
T
A
G
A
A
A
C
A
T
T
A
A
A
T
G
G
A
C
C
18900
A
A
G
A
T
T
A
T
A
T
A
A
A
T
T
T
C
A
G
A
C
C
C
C
A
G
A
A
T
A
C
C
T
G
A
A
T
C
C
A
T
T
C
C
T
G
TCTC
18950 |
REPEAT
|
var(18907):[G:0.36]
TAAGGGATTT TCAACAGCAC AAGACAAATT TATAATTTTG AAAACTTTCA
19000
CTTTGGTGTA TCCAGTTCAT GGGCTATAAT ACTGTTATAT CCCTTGCGTT
19050
TAGAATAGGA TAAACAATGA GATATTATTT TAAAAGAGAA GTCTGTCATT
19100
ACAGCTAAGT TCAAGACTTA TTATAAATAA ATAATAATTT TAAAACATCA
19150
AATTATACTC AATATATGTT GTGGTTCTGC TTTAATTGTG ATGGAATGAA
19200
ACTGCTGTCA CCATGTAGAT TACCGAGTAT AGATAC
C
GTC TATCTTCCTT
19250 |
var(19237):[T:0.03]
ATTATGTGTC TAGAAAGCTA GATTTCAAGT CTTTCAATAA ATATTTTGGG
19300
AAACCTTTCT CCCCAGACTC CAATTCCTTC TCTTTTCCCC ACCATCACTT
19350
TGTTACATTG GTCTGATTTA TGGCAGGTAA GGAAACAAAG CGTGAATCTT
19400
CCCTTTGACT ATTACACCAT CCTGTGGCCT CAGGCTGAGT CAACCACTCT
19450
GCCTCTTGCC TCACTACCTT TTTTCATGGG ATTCCCTCCC CCTCTCCCAA
19500
CCCCTAATTA CAGGGCTCCA TATATAGTCC TCAATAAAAG TTCCCGTCAA
19550
TTTTCAATAA AGAGATTAAT CATGTATGTT GGGTAGGCAA CACCTGAGAT
19600
GAAAAGTGGT AGCAACTTCT CAGAAGCAGC CACATTACTC AACAGCAAGC
19650
TGATGAGAAG TGGAGAAAAA CCACAAACAG CCAAAACCAC AGAGCATTAA
19700
GGATGTGGAG AGTGAGTATT CAAAAATGGA AGTCAGTCCA CACACCAGAA
19750
AGAACATTTT GCCAAGTATT AAAAAAAAGG TTAAAACCCT TATGTTAGTG
19800
ATACAGAAAG CGTCAGGGAT GTTTATCTTC CAGCAAGACA GCACTTTAG
G
19850 |
NOT SCANNED
T
A
A
T
G
C
T
G
T
G
G
T
T
T
C
T
A
T
G
T
G
T
C
C
C
C
C
A
A
A
A
G
T
T
C
A
T
G
T
G
T
T
G
G
A
A
A
C
C
T
19900 |
REPEAT
G
A
T
C
C
C
C
A
G
T
G
C
A
G
C
A
A
T
G
T
T
G
A
G
A
G
G
T
G
G
G
A
C
T
T
T
G
G
G
G
A
G
A
T
G
A
T
T
G
G
19950
G
T
C
A
T
G
A
G
G
A
T
T
C
T
G
C
C
C
C
C
A
T
G
A
A
T
G
G
A
T
T
C
A
T
C
C
A
T
T
G
A
T
G
G
A
T
T
A
A
C
20000
G
A
A
T
T
A
A
T
G
T
G
T
T
A
T
T
G
A
G
G
A
A
G
T
G
G
G
C
T
A
G
T
T
A
T
C
A
A
A
A
A
A
G
T
T
G
G
T
C
T
20050
G
T
T
T
TATATA TATTTTATAT TTTATATATA TATGTATATA TATGTATAT
G
20100 |
REPEAT
C
C
A
T
C
T
C
T
C
T
T
G
A
A
T
C
C
C
T
G
T
G
A
A
G
T
C
C
T
C
T
G
T
C
A
C
C
T
T
A
A
G
T
C
T
C
T
G
C
A
20150 |
var(20120):[A:0.05]
G
A
G
A
G
T
C
C
C
C
A
C
C
A
G
C
A
A
G
A
A
G
G
C
C
C
T
C
A
C
C
A
G
A
T
G
T
G
G
C
T
C
T
T
A
T
G
G
C
T
20200 |
var(20192):[T:0.11]
C
T
T
A
G
A
C
A
T
T
A
G
A
C
T
T
C
C
T
A
G
C
C
T
C
C
A
A
A
A
C
T
G
T
A
A
G
A
A
A
T
A
A
A
T
T
C
C
T
T
20250 |
var(20204):[G:0.01]
T
T
C
T
T
T
A
T
A
A
A
T
T
A
C
C
C
A
G
T
C
T
C
G
G
G
T
A
T
T
C
A
G
T
T
A
T
A
G
C
A
A
C
A
G
A
A
A
A
T
20300
G
G
A
C
T
G
A
A
A
C
A
GTTAATAAG AAGGAATTTT TTTAAAGATT CTGAAGAGGA
20350
GCCATAAGCT ATCATGGTGG TATTGCTACT AGAATCAGGT ATAAAAAATT
20400
ATTAGTCTGA AAATACTGAA GACTCCTTGA GTGGAGAAAA GAAACTCAGA
20450
TCTTTGCCTT TTCCCTGCTA CAG
A
T
A
T
G
G
A
C
A
G
A
G
A
C
A
A
T
G
G
A
A
A
A
A
T
A
A
20500 | Exon 5
Y G Q R Q W K N K 107
A
G
A
A
G
A
C
T
G
T
T
G
G
G
G
T
A
C
T
C
A
A
G
A
A
C
T
C
T
C
T
T
G
T
G
A
C
C
T
T
A
C
C
A
G
T
G
A
A
A
20550
E D C W G T Q E L S C D L T S E 123
C
C
T
C
A
G
A
C
A
T
A
C
A
G
G
A
A
C
C
T
T
A
T
T
A
C
G
G
G
A
G
G
G
T
G
A
G
G
G
C
G
G
C
C
T
C
G
G
C
T
20600
T S D I Q E P Y Y G R V R A A S A 140
G
G
G
A
G
C
T
A
C
T
C
A
G
A
A
T
G
G
A
G
C
A
T
G
A
C
G
C
C
G
C
G
G
T
T
C
A
C
T
C
C
C
T
G
G
T
G
G
G
A
20650
G S Y S E W S M T P R F T P W W E 157
A
A
GTGAGTTC C
A
TGGAGTTT CTTTGCCCTT GTTCTTCCTG CTTTTGGACA
20700 |
var(20662):[G:0.01]
157
GCCCTCCCGG AGCACGGCTA GTGACTAG
G
C
C
T
T
G
T
G
C
T
T
T
G
C
T
G
A
G
G
T
C
T
20750 |
REPEAT
C
T
A
C
A
T
C
A
T
T
A
T
C
T
C
T
T
T
T
G
G
T
C
T
A
A
T
T
G
T
C
A
G
A
A
C
A
A
C
T
C
T
A
G
G
A
G
A
T
A
20800
G
C
T
T
T
T
A
T
T
A
T
C
C
T
A
A
T
T
T
T
C
T
A
G
T
C
C
A
G
A
A
C
A
T
C
A
A
G
A
T
G
T
A
G
A
G
G
C
T
T
20850
T
A
G
T
C
A
T
T
G
C
T
C
C
A
A
T
C
T
C
G
C
G
A
T
C
T
G
T
A
T
T
A
T
C
C
A
A
G
T
C
A
G
G
G
T
T
C
A
A
A
20900
T
T
T
G
C
T
A
T
A
T
C
T
G
A
C
T
G
C
A
G
A
G
C
C
T
C
C
A
C
T
C
CATCAATTT GTCACCTTGT
20950
GTGTGTGTGT GTGTGTGTGT GTTTGTGTGT G
A
C
A
G
G
G
T
C
T
C
G
C
T
T
T
G
T
C
A
21000 |
REPEAT
C
C
C
A
G
G
C
T
G
G
A
G
T
G
C
A
G
T
G
G
C
A
C
G
A
T
C
T
T
G
G
C
T
C
A
C
T
G
C
A
A
C
C
T
C
T
G
C
A
T
21050
C
C
C
G
G
G
T
T
C
A
A
G
C
G
A
T
T
C
T
C
C
G
G
C
C
T
C
T
G
C
C
T
C
C
C
G
A
G
T
A
G
C
T
A
G
G
A
T
T
A
21100
C
A
A
G
T
G
T
G
T
G
C
C
A
C
C
A
C
C
C
T
T
G
G
C
T
A
A
T
T
T
T
T
G
T
A
T
T
T
T
T
A
G
T
A
G
A
G
A
C
G
21150 |
var(21150):[T:0.17]
G
G
G
T
T
T
C
A
T
C
A
T
A
T
T
G
G
C
C
A
G
G
C
T
G
G
T
T
T
C
A
A
A
C
T
C
C
T
G
A
C
C
T
C
A
G
G
T
G
A
21200
T
C
T
G
C
C
C
C
C
T
T
T
G
G
C
C
T
C
C
C
A
A
A
G
T
G
C
T
G
G
G
A
T
T
A
T
G
G
G
T
G
T
G
A
G
C
C
A
C
C
21250
A
T
G
C
C
C
A
G
C
C
CCTAAAAAAG TATTTTTAGA CAGCAGAATT TGTCATAGTG
21300
CCTAGTCCTT CCCCAAACAC GAGGGTTAAG TTCATGAAAA TACTGATTAC
21350
AGGAATTTTC TGTTGAGGAA ATTAAGACTT TTAGTCACCT CCCCAAAAAG
21400
GCAGACCAAA AGTGCTTTCT CAGTATCCAT CCTGAAGGAT ATTTATTCCT
21450
TTTTTAGTTT AGTCACAACC ATAGAATAAT ATAATCTAAG ACATAGGTGT
21500
TAAAATTAAC CATTACCAAC AGACATTGGA TAAAATAGTA GAGAGAGAGA
21550
GAGAAGGGGT TTA
A
T
G
T
A
T
A
G
A
T
A
T
A
A
A
G
A
T
G
T
G
C
A
T
A
A
A
T
A
G
A
A
C
A
A
G
A
21600 |
REPEAT
A
A
A
A
A
A
A
A
A
G
A
T
A
T
T
T
A
C
C
A
C
A
G
T
C
C
T
C
A
T
A
A
T
T
G
C
A
A
C
A
A
G
T
C
A
A
C
T
A
G
21650
T
C
A
T
G
A
A
G
C
T
G
T
A
G
T
T
A
A
T
A
T
T
T
A
T
G
A
C
T
T
C
T
T
C
C
T
T
C
A
T
T
A
T
A
A
A
C
T
C
A
21700 |
var(21700):[C:0.08]
A
C
A
T
T
C
A
C
T
T
T
C
T
T
T
C
C
A
G
C
C
A
G
C
A
C
T
T
C
A
G
C
T
CTTTATC CACGAGGAGT
21750
TTGAGTCCTT TTGGTGTTTC CTGTCTCCGC TTGACCTAAC CTTACATTAA
21800
TTTTTATCAC TGAATAGAGA AGCTCTAAGA GGCACACCAG AGGATACCAA
21850
GAATTCTTCC ACCTGACCCC ATTGTATTTA TAACTATATT A
T
GCCTTGAA
21900 |
var(21892):[C:0.21]
AATCAGAATG AATCACCCTA GACAATATAA GAACCTCATT TTCTTTTTGT
21950
TAGTTAAATG GCATGAGGCG CTCCAAATGG TCAGGAGAGA GCCTCGACTT
22000
CCAATTTTTG GAAACCATTT TTGTTA
T
A
A
A
C
C
A
G
A
A
G
A
A
T
T
C
A
A
G
G
C
C
A
A
22050 |
REPEAT
G
C
A
T
A
T
G
G
G
A
A
A
C
A
A
A
A
A
C
A
T
G
T
C
A
T
A
A
G
T
T
G
T
T
C
A
C
T
A
T
G
G
G
T
A
A
C
A
G
T
22100
C
A
G
A
G
T
T
G
C
C
C
C
T
C
C
C
A
C
T
T
C
T
A
C
T
T
C
T
T
G
T
A
T
C
C
T
A
G
A
C
C
A
G
T
G
A
A
T
T
C
22150
T
G
T
C
T
G
T
G
G
A
A
G
A
A
A
T
A
G
C
A
C
C
A
T
A
T
A
T
T
G
G
C
C
C
T
A
G
G
C
T
T
A
G
T
G
A
A
G
C
A
22200
T
T
T
A
C
C
A
A
T
T
G
G
A
G
C
A
T
T
T
A
C
C
A
A
T
T
C
A
T
A
T
G
C
C
A
A
T
T
C
A
C
A
A
G
A
C
G
T
C
T
22250
C
T
C
A
A
A
C
T
G
A
G
T
T
T
T
C
A
A
T
T
A
T
C
C
A
T
T
T
C
A
C
C
T
T
C
C
T
A
T
A
A
A
G
T
C
A
T
G
G
A
22300
T
T
T
C
T
G
A
G
C
G
A
C
A
A
A
T
A
T
A
T
G
A
T
A
T
A
T
A
T
T
T
G
T
C
C
T
A
T
G
G
G
T
C
T
T
G
A
G
A
C
22350
C
T
T
G
C
T
T
C
A
C
T
C
C
T
T
T
C
A
C
A
T
T
A
A
C
T
T
A
A
G
T
T
C
T
T
T
G
T
C
A
T
A
A
G
C
A
A
T
G
T
22400
A
T
T
G
T
G
G
A
G
T
A
C
T
A
T
G
C
T
C
A
T
G
A
A
C
A
A
G
G
C
A
T
T
G
A
C
T
A
C
A
T
C
T
A
T
G
G
G
T
G
22450
TATGTGTGGT CCCAGGAGTG GTTAGGGGTC TGCTAATAAA AGCATTGAAG
22500
CAGTAAATAA AAATCTATAA ACAAAATCTG TAACCAGAAT CTATATCCAG
22550
CAGTAAAGAA AATCTATAAC CAATGTCTCT TGCCCCCTCC CTTTTGGAAG
22600
GGAACAAAAA TAAACCTACC TGCAACGAGA TGGAAGATGA GAGCCCCTGG
22650
AATA
T
GGCAC TATACTAGGG GTTCAACATT GATCTTCCTT ACTGGAAAGT
22700 |
var(22655):[C:0.07]
TGGACACTCT GCAGGTCAGA CCAACTTTGG TAAGAGGAGA TCCATATTGT
22750
TAAGTCTATA TATAGCCTCC ATCATGCAAC TATTTTGTTC AAGAGCCCAT
22800
AGAGCAACTA CAGGACACTG GGGAAATAGA TGGTCACTGC ATCCACTTAG
22850
ATT
T
T
T
T
T
A
A
A
C
A
G
C
C
T
T
A
T
T
G
A
G
A
T
A
T
A
A
T
T
C
A
C
A
C
A
G
C
C
T
A
T
A
C
T
T
T
A
22900 |
REPEAT
A
G
C
A
T
A
T
A
G
C
A
T
A
C
A
G
T
T
T
A
A
T
G
G
T
T
T
T
T
A
C
T
A
T
A
T
T
C
A
C
A
A
A
T
A
T
G
T
A
C
22950
A
A
C
C
A
T
C
A
C
T
C
A
C
A
G
T
C
A
A
T
T
T
T
A
G
A
A
C
A
T
T
T
T
T
A
T
C
A
C
C
T
C
A
A
A
A
A
G
C
A
23000
A
C
T
C
C
A
T
A
C
C
C
T
T
T
G
G
C
T
A
T
C
A
C
C
T
T
C
C
A
G
T
C
T
C
A
C
C
A
T
T
C
C
C
T
T
A
G
C
C
C
23050 |
var(23048):[T:0.02]
T
C
A
G
C
C
C
C
G
G
C
A
A
C
T
A
C
T
A
A
T
C
T
T
T
C
T
G
T
C
T
C
T
A
T
A
G
A
G
T
T
C
C
C
T
G
T
T
C
T
23100 |
var(23058):[T:0.42]
A
G
A
T
A
G
A
C
T
C
A
T
A
T
A
A
T
A
C
A
T
G
A
T
T
T
T
T
T
T
G
A
C
T
G
G
C
T
T
C
T
T
T
C
A
C
T
T
A
A
23150 |
var(23110):[A:0.37]
C
G
T
G
T
T
T
T
C
A
A
A
G
T
T
C
A
T
T
C
A
G
A
T
T
G
T
A
G
T
A
T
G
T
A
T
C
A
G
T
A
C
T
T
C
A
T
T
C
T
23200
T
T
T
T
T
G
T
G
A
C
C
A
A
A
T
A
A
T
A
C
A
T
T
A
T
A
T
G
G
A
T
A
T
A
C
C
A
C
A
T
A
T
T
A
T
T
T
A
T
C
23250
C
T
T
T
C
T
T
C
A
G
T
T
G
A
T
A
G
A
C
A
T
T
T
G
G
G
T
A
G
T
T
T
C
C
A
C
T
T
T
T
T
G
G
C
T
A
T
T
A
T
23300 |
var(23275):[A:0.40]
G
A
A
T
A
A
T
G
C
T
A
C
T
A
T
A
A
A
C
A
G
T
C
A
T
G
T
A
A
A
A
A
T
T
T
T
T
G
A
G
T
G
T
G
A
G
T
T
T
T
23350
T
T
T
G
T
T
T
T
T
T
T
T
T
C
T
T
G
T
T
T
G
T
T
T
T
T
T
T
G
A
G
A
G
A
C
A
G
G
A
T
C
C
T
G
C
T
C
T
G
T
23400 |
REPEAT
C
A
C
C
T
G
G
G
C
T
G
G
A
G
C
G
C
A
G
T
G
G
C
A
C
A
A
A
C
A
T
A
G
C
T
C
A
C
T
T
C
A
G
T
C
T
T
G
A
A
23450 |
var(23415):[T:0.02]
C
C
C
C
T
G
G
G
C
T
C
C
A
G
C
A
A
T
C
C
T
T
C
C
A
C
C
T
C
A
G
C
C
T
C
C
C
A
A
G
T
A
C
C
A
A
G
G
A
C
23500 |
var(23483):[T:0.01]
|
var(23493):[G:0.03]
T
A
T
C
A
G
G
C
A
T
A
C
G
C
C
A
C
C
A
C
A
C
ATAGC
T
G
G
G
C
A
T
A
C
C
T
T
T
A
T
A
T
T
T
C
T
C
T
23550 |
REPEAT
T
C
A
A
T
A
T
A
T
A
C
A
T
A
G
G
A
G
T
G
G
A
A
T
T
G
C
T
G
G
G
T
C
T
C
A
T
A
G
T
A
A
C
T
C
T
A
T
A
T
23600
T
T
A
A
T
C
A
T
T
T
G
A
G
G
A
A
A
T
G
C
C
A
G
A
C
T
A
C
T
T
T
C
A
A
A
G
C
A
T
C
T
G
C
A
C
T
A
T
T
T
23650
T
A
C
A
T
T
C
C
C
A
T
C
A
G
C
A
A
T
A
T
A
T
G
A
G
A
G
T
T
T
T
G
A
T
T
T
T
T
C
C
A
C
A
T
T
T
T
T
A
C
23700 |
var(23656):[C:0.01]
C
A
A
T
C
T
T
T
T
T
T
G
A
C
T
A
T
A
G
C
C
A
T
C
C
T
A
A
T
A
G
G
T
A
T
A
A
A
A
T
G
G
T
A
A
C
T
C
A
T
23750 |
var(23743):[C:0.02]
G
T
G
G
T
T
T
T
T
A
T
T
T
G
C
A
T
T
T
A
C
C
T
G
C
T
A
A
T
T
A
A
T
G
A
T
G
T
T
G
A
G
C
T
T
C
T
G
T
T
23800
T
T
A
T
G
C
T
T
A
T
T
G
G
C
T
A
T
T
T
T
G
T
A
C
C
T
T
C
C
T
T
G
G
A
G
A
A
T
T
G
T
C
C
A
T
T
G
A
G
A
23850
T
C
C
T
T
T
G
C
C
C
A
T
T
T
A
A
A
A
A
A
T
T
T
A
A
T
C
A
A
A
T
C
T
T
T
T
T
A
T
T
T
T
T
G
A
G
T
T
G
T
23900
A
A
G
G
G
T
T
C
T
T
T
A
T
A
T
A
T
T
C
T
G
C
A
T
A
C
C
A
A
T
G
C
C
T
T
A
T
C
A
G
A
T
A
T
A
T
G
A
T
C
23950 |
var(23904):[T:0.02]
C
T
C
A
G
C
T
A
G
C
T
C
C
T
C
C
C
A
T
T
C
T
G
T
G
A
G
T
T
G
T
C
T
T
T
T
T
A
C
T
T
T
C
T
T
G
A
T
G
G
24000
T
A
T
C
A
C
T
T
G
A
C
A
C
C
A
A
G
T
T
T
T
A
A
A
C
T
T
G
G
A
T
G
A
A
A
T
C
C
A
A
T
T
T
A
T
T
T
C
T
T
24050
C
T
T
T
T
G
T
T
G
C
T
T
G
T
G
C
T
T
T
T
G
G
T
G
T
C
A
T
A
T
C
T
A
A
G
A
A
T
C
C
T
T
T
G
C
C
A
A
A
T
24100 |
var(24068):[A:0.02]
C
C
A
A
A
A
T
C
A
T
G
A
A
G
A
T
T
T
A
C
C
C
T
A
T
G
T
T
T
T
C
T
C
C
T
A
A
G
A
G
T
T
T
T
A
T
A
G
T
T
24150 |
var(24103):[G:0.01]
T
T
A
T
C
T
C
T
C
A
C
A
G
T
T
A
A
G
T
C
T
G
A
T
T
C
A
T
T
T
T
G
A
G
T
T
A
A
T
T
T
T
T
G
T
A
T
G
T
G
24200
G
T
G
T
G
A
G
G
T
A
A
G
G
G
T
C
C
A
A
T
A
T
T
A
T
T
C
T
T
T
G
A
C
A
T
A
T
G
A
C
T
A
T
C
C
A
G
C
T
G
24250
T
C
C
C
A
G
C
A
C
C
A
T
T
T
G
T
T
G
A
A
A
A
T
T
A
T
C
C
C
A
T
T
G
A
G
A
G
T
T
C
T
T
G
G
C
A
C
A
C
T
24300
T
G
T
T
G
A
A
A
A
T
C
A
A
T
A
G
A
C
C
A
T
A
G
A
C
G
T
G
T
A
G
T
T
T
A
T
T
T
C
C
A
G
A
C
T
C
T
C
A
A
24350 |
var(24330):[G:0.02]
|
var(24346):[T:0.02]
T
T
C
T
A
T
T
C
T
A
T
T
G
A
G
C
T
A
T
A
C
A
T
T
C
A
T
C
A
T
T
G
T
G
C
C
C
A
T
A
C
C
A
C
A
C
T
A
T
T
24400
T
T
G
A
T
T
A
T
T
G
T
T
G
C
T
T
T
G
T
A
G
T
A
A
G
C
T
T
T
G
A
A
A
T
T
G
G
G
A
A
G
G
G
T
G
A
G
C
C
C
24450
T
C
C
T
C
T
T
T
A
T
T
C
A
T
C
T
T
T
T
T
C
A
A
G
A
T
T
G
T
T
T
T
G
A
C
T
A
T
T
A
T
G
G
G
T
T
C
C
T
T
24500
G
C
A
A
T
T
C
TCT AACCA
C
CCAG ATTTTTTAAG ACCACTTTTC AGTATGAGCC
24550 |
var(24516):[T:0.02]
TTTTGCTTTG CATTCATATG GCCACAGAAA TATTCACATT CTGTATCTTA
24600
GTACTTAGGG ATCCATCCAT ACACCTCTTC TAACTGGTGC AAGGTCCAGT
24650
GAGATCCAAA TTAATTAGAT ACTGTCCAAA ATGCTAGATG CATTTTCCCC
24700
CAACTCTCTA ATTAGCAGGA GGGTGGAATA GAGTTGAGCA AACTAATTCA
24750
TGGTAACTCT TGGTTGTCTC TTGGATACAT TGAAATTCAA AGCCAATATA
24800
CTCAACAAGC AATTCTCTAG TAGAGGAAAA GGAGATTTCA TGACTAAACT
24850
GATGAACACC AGTGAAGGGA ATTCACAGAT CAGTGTGATT ATTATATTCA
24900
AGCCTAGAAA TAGGGTCACA TTCAAATTTA CTTATCAAAC AAAGTTTCCT
24950
TCAGTCTAAG CCATTAGGCC AGTCAGGTAA GAATAGCCAA AGACATTGAC
25000
TGACACAGCT TTAGCTCAAT TCT
A
T
T
T
A
A
A
T
T
G
G
G
A
T
A
G
T
G
T
T
G
A
G
T
T
A
A
25050 |
NOT SCANNED
G
A
A
G
G
G
T
T
T
G
T
G
T
G
T
T
T
T
C
T
G
T
A
T
G
A
C
C
T
T
T
C
T
C
C
C
T
A
A
A
A
A
A
A
A
A
A
A
A
A
25100
A
A
A
A
A
A
A
A
A
A
A
A
T
C
A
G
A
A
A
A
G
A
A
A
A
G
A
A
A
A
G
A
A
A
A
A
A
G
C
T
T
T
A
G
A
C
C
A
G
G
25150
T
C
C
T
T
T
A
AAA AGCCATTTTA TTTCGGGGCC TCTTAGTAGA AGAATAAGAA
25200
ACCCAGTCTA TAGCTACTAC TCTTGTTGAT GCAATAGTGA GAAGAATCAC
25250
CCACTCAGCT GCCTCCTCAC CCCCAGGCTT GCGCTCTCCC ACCACAGCTC
25300
CTAAGAACTT CTGAAGAACA TATTTCAAAA AAGCACGTTT CTAGTTCCTC
25350
AAGACAGCAT GTTTGTGGCA TCTGTGATAT AGACTAATGA GCCAGCTGCA
25400
TG
C
ATTG
C
CT CCTCTGACAC CTGTTTTTGA GCAGCAGGAT GTTATCTTAG
25450 |
var(25403):[T:0.20]
|
var(25408):[G:0.02]
ATTAAGAAGT TCTGATTTAT GGTGTCTATC TAGAGACAAA GCAAGATTTT
25500
AAAAATAAAA TAAAACAAAG TAAACTTTCT TCAGTTAAAA GCAGC
G
TTTG
25550 |
var(25546):[A:0.03]
ATACTTAGCG AGATTTCAGT ATTATTTGAC CCTAGAATTA CTTGGATTAA
25600
AAATAGATGT GAAG
G
C
C
A
G
G
T
G
T
G
T
T
G
G
C
T
C
C
A
T
G
C
C
T
G
T
A
A
T
C
C
C
A
G
C
A
25650 |
REPEAT
|
var(25619):[A:0.03]
C
T
T
T
G
G
G
A
G
G
C
C
G
A
G
G
T
A
G
G
A
G
G
A
T
C
A
C
T
T
G
A
G
G
C
A
A
A
G
A
A
T
A
G
A
G
C
A
T
T
25700 |
REPEAT
T
C
A
A
G
C
A
A
G
G
G
A
C
C
A
G
C
A
T
T
T
G
C
A
A
A
G
G
C
C
C
T
C
T
G
G
C
A
T
A
G
C
A
A
A
C
T
C
A
A
25750
G
G
G
A
C
T
G
A
A
A
G
A
T
A
A
C
C
A
A
T
A
T
A
T
T
G
A
A
G
A
A
G
A
G
C
A
T
G
C
A
G
G
A
A
G
G
A
G
T
C
25800
C
A
T
A
A
T
G
A
G
A
T
G
G
G
A
C
T
G
G
A
A
A
G
G
T
A
G
G
C
A
G
G
T
A
C
A
A
G
A
A
T
T
T
T
T
T
A
A
G
G
25850
A
G
T
T
G
T
G
A
C
T
T
C
C
T
C
C
A
G
A
A
A
A
A
C
A
T
A
A
T
T
T
T
A
T
T
C
A
G
G
A
G
C
C
A
T
A
T
G
A
T
25900 |
var(25886):[T:0.38]
C
A
G
A
C
T
T
G
T
G
T
A
T
A
G
A
A
A
A
G
A
T
C
A
T
T
T
T
G
A
C
T
A
T
A
T
T
T
T
G
G
G
G
A
A
C
A
G
G
T
25950
T
G
G
A
T
G
C
A
G
A
T
A
A
G
T
G
A
A
G
T
A
G
C
A
G
G
T
T
A
C
T
A
A
T
A
A
T
A
G
T
C
T
A
C
A
G
G
A
G
A
26000 |
var(25974):[G:0.21]
C
C
G
A
A
T
T
T
G
G
C
T
T
A
T
G
A
A
A
A
G
G
A
C
T
A
G
A
G
A
A
A
A
T
T
T
A
T
T
C
C
T
G
G
A
G
G
G
A
C
26050
A
T
T
T
A
G
T
A
A
G
C
A
A
C
A
T
T
G
G
C
A
G
G
A
C
C
A
G
G
T
G
A
T
A
G
A
T
C
G
G
A
T
A
T
A
A
T
G
G
T
26100
G
A
A
G
A
G
G
A
C
A
T
G
T
C
A
A
A
G
A
T
G
A
C
C
T
C
T
A
A
G
T
T
T
C
T
T
G
C
A
T
G
C
A
T
A
A
T
T
A
G
26150
A
T
G
A
A
T
T
G
C
T
G
A
G
A
T
C
T
T
T
T
T
G
A
T
G
G
G
G
T
T
T
G
A
T
G
A
A
A
A
A
G
A
C
C
A
G
T
T
T
G
26200
G
T
G
G
G
A
T
G
C
A
A
G
G
T
A
A
T
A
G
A
G
A
T
T
A
T
G
A
G
T
T
T
G
G
T
T
T
T
G
A
A
T
A
T
G
T
T
A
A
G
26250
C
T
T
A
A
T
A
T
G
C
T
T
T
T
A
A
G
A
G
A
T
C
C
A
G
G
G
G
A
C
A
T
A
T
C
T
C
T
T
C
A
G
A
T
C
C
A
A
G
A
26300
C
T
C
A
A
A
G
T
A
A
A
G
T
C
T
T
T
A
T
T
A
G
A
G
A
C
A
A
A
A
A
T
T
T
G
T
G
A
G
T
C
A
T
T
T
C
A
T
G
C
26350
A
T
A
C
A
G
T
A
C
A
G
T
G
G
A
C
A
T
T
G
A
T
A
G
G
A
T
T
G
C
C
T
A
G
G
G
A
G
A
G
A
G
T
A
G
T
G
A
G
T
26400
G
A
G
A
G
G
C
A
G
T
T
T
T
G
A
G
T
A
A
G
A
C
C
A
G
A
T
A
T
T
G
A
G
G
G
A
C
T
T
T
C
A
C
C
C
A
A
A
G
A
26450
T
G
C
C
T
G
A
G
T
A
A
G
A
A
A
A
A
T
C
T
T
A
A
A
A
G
G
A
G
A
C
T
G
A
G
A
A
G
G
A
A
T
A
G
C
C
A
A
A
G
26500
A
G
G
T
A
G
G
A
G
G
A
A
A
T
C
T
G
T
G
G
G
C
T
G
A
T
A
T
G
T
T
C
A
T
G
A
A
T
A
G
T
G
C
G
G
G
A
A
G
G
26550 |
var(26544):[A:0.17]
T
A
A
T
A
T
T
T
C
A
A
G
G
A
G
A
G
A
G
C
T
G
T
T
A
A
A
G
A
G
T
A
A
A
G
T
G
C
T
A
T
G
A
G
G
T
C
A
A
A
26600
T
A
A
TCTTGAC TTGGTCTTGT AACACAATCA CAATCCAGTG AATGGGTCAA
26650
GAAACTTGCA ACTGATTGCA AAACTGATTT TGCAATCAAT TGCAAAATCT
26700
AGCATCACAG ATCATAAGCC AGGAGCCCTG TGATGTCCGC AGCTGACTCA
26750
CTGATAGGAC AATGCCTGAA ATATGTGCCT CACTACAAAA GGGACATGTT
26800
TATTTAAAGT TAACTATCCC ATTATTCCAA TATAGTTGGA AAGTGCTTTA
26850
AAAACT
T
A
T
G
G
T
T
C
C
A
A
A
T
T
A
A
A
T
A
G
C
C
T
G
G
G
A
G
T
A
G
G
A
A
A
C
T
C
T
C
T
T
C
T
26900 |
REPEAT
T
C
T
A
A
A
A
C
A
C
T
T
A
G
A
A
A
T
T
C
T
G
G
A
T
A
A
A
A
C
A
C
A
T
T
C
T
C
C
A
A
A
C
T
C
C
A
C
A
G
26950
A
G
G
G
G
C
A
A
A
A
A
T
A
A
A
A
A
T
A
A
A
G
G
G
A
A
T
C
C
T
T
G
G
G
G
G
C
C
A
A
A
A
C
A
A
A
G
T
A
A
27000
A
C
G
G
A
A
A
T
C
A
A
A
G
G
G
G
A
A
C
C
A
G
A
A
G
A
C
C
A
A
C
A
C
A
G
T
G
A
C
T
G
C
C
C
C
A
G
C
T
G
27050
C
C
C
T
G
A
A
G
G
C
A
T
T
T
G
C
T
G
G
A
T
G
T
G
G
T
A
A
C
T
A
G
A
C
C
C
T
A
A
G
T
G
G
T
A
A
C
A
G
C
27100
C
A
C
T
C
C
C
A
G
G
A
C
A
A
A
A
G
A
C
A
A
G
G
T
T
T
T
A
G
G
C
C
A
G
C
A
C
A
A
G
G
C
A
G
G
G
A
G
T
T
27150
A
G
A
A
C
T
A
A
T
A
C
C
C
C
T
A
C
A
A
A
A
G
T
C
T
T
A
G
A
A
C
C
T
C
C
A
A
G
G
G
C
T
A
C
A
C
T
G
T
C
27200
A
A
T
A
A
A
A
A
G
T
C
A
G
A
C
T
A
G
C
C
T
G
G
A
T
G
T
G
G
T
G
G
C
A
T
G
C
A
C
C
T
G
T
A
A
T
C
T
C
A
27250 |
REPEAT
G
C
T
A
C
T
C
A
G
G
A
A
G
C
T
G
A
A
G
G
A
G
A
A
T
C
A
C
T
T
G
A
G
T
A
C
A
G
G
A
G
T
T
T
G
A
G
C
C
C
27300
A
G
C
C
T
G
G
G
C
A
A
C
A
T
A
A
T
G
A
G
A
T
C
C
T
G
T
C
T
C
A
A
A
A
A
A
A
A
A
C CCAAAACCAA
27350
CCAACCAAAC AAACAAA
C
A
A
A
A
GTCAGATT AAGAAAAGCC CTTCCAATAA
27400 |
var(27368):[:0.02]
ACAGAGGAAA GTAATTTGTA TGTTTCCATC TTTATTCTGC TAAGAATCTA
27450
ACACTCCCTA CATTTATAAA GGTTCGAGAT TCAAATACAT ATGCAA
T
T
T
T
27500 |
REPEAT
C
T
T
T
T
T
T
A
T
T
T
T
T
G
T
T
T
T
T
T
G
A
C
A
T
G
G
G
T
T
T
C
A
C
T
A
T
G
C
C
A
C
A
C
A
A
G
C
T
A
27550
T
A
G
T
G
C
A
G
T
G
G
C
A
T
G
A
T
C
A
T
A
G
C
T
C
A
C
T
G
C
A
G
C
C
T
C
G
G
C
C
T
C
C
C
T
G
G
G
C
T
27600
C
A
G
G
T
G
A
T
C
C
T
C
C
C
A
C
C
ATG CTGATTTGTC ATTATACATA ATGCGTCTGT
27650 |
var(27612):[G:0.06]
ATATAATACA TTCCTTT
G
AT GATTTGTCAA ATTTTTATGT TTTTTCTTCA
27700 |
var(27668):[A:0.02]
G
C
A
A
A
A
A
T
A
G
A
T
C
C
T
C
C
A
G
T
C
A
T
G
A
A
T
A
T
A
A
C
C
C
A
A
G
T
C
A
A
T
G
G
C
T
C
T
T
T
27750 | Exon 6
T K I D P P V M N I T Q V N G S L 174
G
T
T
G
G
T
A
A
T
T
C
T
C
C
A
T
G
C
T
C
C
A
A
A
T
T
T
A
C
C
A
T
A
T
A
G
A
T
A
C
C
A
A
A
A
G
G
A
A
A
27800 |
var(27797):[A:0.01]
L V I L H A P N L P Y R Y Q K E 190
A
A
A
A
T
G
T
A
T
C
T
A
T
A
G
A
A
G
A
T
T
A
C
T
A
T
G
A
A
C
T
A
C
T
A
T
A
C
C
G
A
G
T
T
T
T
T
A
T
A
27850
K N V S I E D Y Y E L L Y R V F I 207
A
T
T
A
A
C
A
A
T
T
C
A
C
T
A
G
A
A
A
A
G
GTAAGTTCA GATGAATAGA TATATTTAGA
27900
I N N S L E K 214
GTTTTTTTCT TTTGTTTATT TAACCAATAT TGTGGTCATA TGAGATGTCC
27950
TCTTCTGCTA CTCTGCCTCC TCTTACTTTT CCTTATCTTT AATTTCTTCT
28000
TACTCTCAGC CATCATTGAT CAACGGTTGG TGGTGGCATC ACCATCAGAA
28050
TGTGTGTGTG CCCTTTCCAT CCTC
C
GGTTT GTCTCTACAG TCTTCCCTGC
28100 |
var(28075):[T:0.09]
ATATCTAAAG ATTGGTATTA ACCGTATTTA ATTGCATGTG ACTGCCACAA
28150
ATATTCATTT TTACGGGCTT TGCACACCTT ATTTATTTAT TTATTTATTT
28200
ATTTATTTAT TTATTTATTA TGTA
T
T
T
T
A
T
T
T
T
T
A
G
A
C
C
A
G
G
T
G
T
C
A
C
T
C
28250 |
REPEAT
T
G
T
C
A
C
C
C
A
G
G
C
T
G
G
A
G
T
A
C
A
G
T
G
G
T
G
A
T
C
A
T
A
G
C
T
C
A
C
T
G
T
A
G
C
C
T
C
T
A
28300
A
C
T
T
C
T
G
G
G
C
T
T
A
A
G
T
G
G
T
C
C
T
C
C
T
T
C
T
T
C
A
G
C
C
T
C
C
T
G
A
G
T
A
G
C
T
G
G
G
A
28350
C
T
A
G
A
A
G
C
A
T
G
C
C
C
A
T
C
A
C
A
T
C
C
A
G
C
T
T
T
T
T
T
T
T
T
T
T
T
T
T
T
T
T
T
T
T
T
T
T
T
28400
T
T
T
T
T
T
G
T
A
G
A
G
G
C
A
A
G
G
T
C
T
C
A
C
T
A
T
G
T
T
G
C
C
C
A
G
G
C
T
G
G
T
C
T
C
A
A
A
C
T
28450 |
NOT SCANNED
C
C
T
G
G
C
C
T
C
A
A
C
C
A
A
T
C
C
T
C
C
A
G
C
C
T
T
G
G
C
C
T
C
C
C
A
A
A
G
T
G
C
T
G
G
G
A
T
T
G
28500
C
A
G
G
C
A
T
A
A
G
C
C
A
C
C
T
C
C
C
C
G
G
C
C
T
C
A
C
A
C
C
T
T
A
T
T
T
T
A
A
A
A
T
A
G
C
T
T
T
T
28550
G
A
A
T
C
A
C
A
T
G
A
T
T
A
T
T
T
T
T
G
T
G
C
C
A
G
T
T
T
T
G
C
T
G
C
G
A
T
T
T
T
T
T
T
T
T
T
G
A
G
28600 |
REPEAT
A
C
A
G
G
G
T
C
T
G
A
C
T
C
T
G
T
C
A
C
C
C
A
G
G
C
T
G
G
G
G
T
G
C
A
G
C
A
G
T
G
C
A
A
T
C
A
C
A
G
28650 |
var(28630):[A:0.21]
C
T
C
A
C
G
G
C
A
G
C
C
T
C
A
A
C
A
T
C
C
T
G
G
G
C
T
C
A
A
A
T
G
A
T
C
C
T
C
C
C
A
C
C
T
C
A
G
C
C
28700 |
var(28655):[T:0.02]
T
C
C
C
A
A
G
T
A
G
C
T
G
G
G
A
C
T
A
C
A
G
G
T
G
C
A
T
G
C
C
A
C
C
A
T
G
C
C
C
A
G
C
T
A
T
G
T
T
T
28750
T
T
T
T
G
T
A
C
T
T
T
T
A
G
T
A
G
G
G
A
C
A
G
G
C
T
C
T
G
G
C
C
A
T
G
T
T
G
C
C
C
G
G
G
C
T
G
G
T
C
28800
T
T
A
A
A
C
T
C
C
T
G
G
G
A
T
C
A
A
C
T
G
A
T
C
T
G
C
C
T
G
C
C
T
T
G
G
C
C
T
C
C
C
A
A
A
C
T
G
C
T
28850 |
NOT SCANNED
G
G
C
A
T
T
A
C
A
A
A
C
A
T
G
A
G
C
C
A
C
C
A
G
G
C
C
T
G
G
C
C
T
T
G
C
A
G
T
G
G
T
A
T
T
C
T
A
A
T
28900
C
C
A
C
C
A
T
C
G
G
T
G
C
T
T
C
T
G
T
C
T
G
G
A
T
T
T
G
G
T
G
G
A
T
A
A
T
T
GA ATTTGTTCCT
28950
TTTTTGGTGC CATCTAAGAT GAGGGGTTTT TGTCGTAAGG AGCAGAAACC
29000
ACAGTTTAAC TTGTTTAGAA ACAAAAGAGG AGGGGAGGGA TAATTAGGAG
29050
ATAGGCAAGC AATCTCAGGG ACAGAGGCAG GACGTAGAGT GCCGGCAGCC
29100
TTAGTGGTGA CTGGGAAGGG AAACGGAAGT GAGTTCTAAG GGATCCTGCT
29150
CTGTCTCTCA GACTTTCTGT CTCTATGTGG CCACAGTTTC ATGCCTGCAG
29200
TTATCTCTGC TCATCTCGCT GCACATCATT CTCACTGCAC ACTTCAAATT
29250
CTTAAAAAGA A
G
G
C
C
A
G
G
T
G
G
G
G
T
G
G
T
T
C
A
T
G
C
C
T
G
T
A
A
T
C
C
C
A
G
C
A
C
T
T
29300 |
REPEAT
T
G
G
G
A
G
G
C
T
G
A
G
G
C
A
G
G
C
A
A
A
T
C
A
T
T
T
G
A
G
G
T
C
A
G
G
A
G
T
T
C
A
A
G
A
C
C
T
G
C
29350
C
T
G
G
T
C
A
A
C
A
T
G
G
T
G
A
A
A
C
T
C
C
A
T
C
T
C
T
A
C
T
G
A
A
A
A
T
A
C
A
A
A
A
A
T
T
A
G
C
C
29400
A
G
G
C
G
T
G
G
T
G
G
T
A
T
G
C
G
T
C
T
G
C
A
A
T
C
C
C
A
G
C
T
A
C
T
C
A
G
G
A
G
G
C
T
G
A
G
G
C
A
29450
C
G
A
G
A
A
T
C
T
C
T
T
G
A
A
C
C
T
G
A
G
A
G
G
C
A
G
A
G
G
T
T
G
C
A
G
T
G
A
G
C
C
G
A
G
A
T
G
G
T
29500
G
A
C
A
C
T
G
C
A
C
T
C
C
A
G
G
C
T
G
G
A
T
G
A
T
G
G
A
G
T
G
A
A
A
C
T
G
T
A
T
C
T
C
A
A
A
A
A
A
C
29550
A
A
A
C
A
A
A
A
TT CTTAAAAACA AGACTCTGAC CATGGGGTCA ACCAGCCAAC
29600
AGCCCTCAAG GAGAAGTCAA GTTGCACCTA CACAGCCACT TGCCTTGTCC
29650
CTTTACCAGG CTATGGCCTA GGACTCTAGA AAAGAAGGAT GTGTCTGGGA
29700
AGAAACCCCA CAACCCATCT ACTGCTGTGA CCATGTACAA CTTGTTAATT
29750
TAAACAAAAA TGCAGCTGTG ACTTAATGGC AGCCATTTAC CAACTGATTA
29800
TTTTCTCTCT CGTGTGTAG
G
A
G
C
A
A
A
A
G
G
T
T
T
A
T
G
A
A
G
G
G
G
C
T
C
A
C
A
G
A
G
29850 | Exon 7
E Q K V Y E G A H R 224
C
G
G
T
T
G
A
A
A
T
T
G
A
A
G
C
T
C
T
A
A
C
A
C
C
A
C
A
C
T
C
C
A
G
C
T
A
C
T
G
T
G
T
A
G
T
G
G
C
T
29900
A V E I E A L T P H S S Y C V V A 241
G
A
A
A
T
A
T
A
T
C
A
G
C
C
C
A
T
G
T
T
A
G
A
C
A
G
A
A
G
A
A
G
T
C
A
G
A
G
A
A
G
T
G
A
A
G
A
G
A
G
29950
E I Y Q P M L D R R S Q R S E E R 258
A
T
G
T
G
T
G
G
A
A
A
T
T
C
C
A
T
G
A
C
T
T
G
T
G
G
A
A
T
T
T
G
G
C
A
T
T
C
A
G
C
A
A
T
G
T
G
G
A
A
30000 |
UTR
C V E I P 263
A
T
T
C
T
A
A
A
G
C
T
C
C
C
T
G
A
G
A
A
C
A
G
G
A
T
G
A
C
T
C
G
T
G
T
T
T
G
A
A
G
G
A
T
C
T
T
A
T
T
30050
T
A
A
A
A
T
T
G
T
T
T
T
T
G
T
A
T
T
T
T
C
T
T
A
A
A
G
C
A
A
T
A
T
T
C
A
C
T
G
T
T
A
C
A
C
C
T
T
G
G
30100
G
G
A
C
T
T
C
T
T
T
G
T
T
T
A
T
C
C
A
T
T
C
T
T
T
T
A
T
C
C
T
T
T
A
T
A
T
T
T
C
A
T
T
T
G
T
A
A
A
C
30150 |
var(30116):[C:0.16]
T
A
T
A
T
T
T
G
A
A
C
G
A
C
A
T
T
C
C
C
C
C
C
G
A
A
A
A
A
T
T
G
A
A
A
T
G
T
A
A
A
G
A
T
G
A
G
G
C
A
30200
G
A
G
A
A
T
A
A
A
G
T
G
T
T
C
T
A
T
G
A
A
A
T
T
C
A
G
A
A
C
T
T
T
A
T
T
T
C
T
G
A
A
T
G
T
A
A
C
A
T
30250
C
C
C
T
A
A
T
A
A
C
A
A
C
C
T
T
C
A
T
T
C
T
T
C
T
A
A
T
A
C
A
G
C
A
A
A
A
T
A
A
A
A
A
T
T
T
A
A
C
A
30300
A
C
C
A
A
G
G
A
A
T
A
G
T
A
T
T
T
A
A
G
A
A
A
A
T
G
T
T
G
A
A
A
T
A
A
T
T
T
T
T
T
T
A
A
A
A
T
A
G
C
30350
A
T
T
A
C
A
G
A
C
T
G
A
G
G
C
G
G
T
C
C
T
G
A
A
G
C
A
A
T
G
G
T
T
T
T
T
C
A
C
T
C
T
C
T
T
A
T
T
G
A
30400 |
var(30366):[A:0.01]
G
C
C
A
A
T
T
A
A
A
T
T
G
A
C
A
T
T
G
C
T
T
T
G
A
C
A
A
T
T
T
A
A
A
A
C
T
T
C
T
A
T
A
A
A
G
G
T
G
A
30450
A
T
A
T
T
T
T
T
C
A
T
A
C
A
T
T
T
C
T
A
T
T
T
T
A
T
A
T
G
A
A
T
A
T
A
C
T
T
T
T
T
A
T
A
T
A
T
T
T
A
30500
T
T
A
T
T
A
T
T
A
A
A
T
A
T
T
T
C
T
A
C
T
T
A
A
T
G
A
A
T
C
A
A
A
A
T
T
T
T
G
T
T
T
T
A
A
A
G
T
C
T
30550 |
var(30533):[C:0.02]
A
C
T
T
T
A
T
G
T
A
A
A
T
A
A
G
A
A
C
A
G
G
T
T
T
T
G
G
G
G
A
A
A
A
A
A
A
T
C
T
T
A
T
G
A
T
T
T
C
T
30600
G
G
A
T
T
G
A
T
A
T
C
T
G
A
A
T
T
A
A
A
A
C
T
A
T
C
A
A
C
A
A
C
A
A
G
G
A
A
G
T
C
T
A
C
T
C
T
G
T
A
30650 |
var(30643):[G:0.10]
C
A
A
T
T
G
T
C
C
C
T
C
A
T
T
T
A
A
A
A
G
A
T
A
T
A
T
T
A
A
G
C
T
T
T
T
C
T
T
T
T
C
T
G
T
T
T
G
T
T
30700
T
T
T
G
T
T
T
T
G
T
T
T
A
G
T
T
T
T
T
A
A
T
C
C
T
G
T
C
T
T
A
G
A
A
G
A
A
C
T
T
A
T
C
T
T
T
A
T
T
C
30750
T
C
A
A
A
A
T
T
A
A
A
T
G
T
A
A
T
T
T
T
T
T
T
A
G
T
G
A
C
A
A
A
G
A
A
G
A
A
A
G
G
A
A
A
C
C
T
C
A
T
30800
T
A
C
T
C
A
A
T
C
C
T
T
C
T
G
G
C
C
A
A
G
A
G
T
G
T
C
T
T
G
C
T
T
G
T
G
G
C
G
C
C
T
T
C
C
T
C
A
T
C
30850
T
C
T
A
T
A
T
A
G
G
A
G
G
A
T
C
C
C
A
T
G
A
A
T
G
A
T
G
G
T
T
T
A
T
T
G
G
G
A
A
C
T
G
C
T
G
G
G
G
T
30900
C
G
A
C
C
C
C
A
T
A
C
A
G
A
G
A
A
C
T
C
A
G
C
T
T
G
A
A
G
C
T
G
G
A
A
G
C
A
C
A
C
A
G
T
G
G
G
T
A
G
30950
C
A
G
G
A
G
A
A
G
G
A
C
C
G
G
T
G
T
T
G
G
T
A
G
G
T
G
C
C
T
A
C
A
G
A
G
A
C
T
A
T
A
G
A
G
C
T
A
G
A
31000
C
A
A
A
G
C
C
C
T
C
C
A
A
A
C
T
G
G
C
C
C
C
T
C
C
T
G
C
T
C
A
C
T
G
C
C
T
C
T
C
C
T
G
A
G
T
A
G
A
A
31050
A
T
C
T
G
G
T
G
A
C
C
T
A
A
G
G
C
T
C
A
G
T
G
T
G
G
T
C
A
A
C
A
G
A
A
A
G
C
T
G
C
C
T
T
C
T
T
C
A
C
31100 |
var(31074):[C:0.16]
T
T
G
A
G
G
C
T
A
A
G
T
C
T
T
C
A
T
A
T
A
T
G
T
T
T
A
A
G
G
T
T
G
T
C
T
T
T
C
T
A
G
T
G
A
G
G
A
G
A
31150
T
A
C
A
T
A
T
C
A
G
A
G
A
A
C
A
T
T
T
G
T
A
C
A
A
T
T
C
C
C
C
A
T
G
A
A
A
A
T
T
G
C
T
C
C
A
A
A
G
T
31200
T
G
A
T
A
A
C
A
A
T
A
T
A
G
T
C
G
G
T
G
C
T
T
C
T
A
G
T
T
A
T
A
T
G
C
A
A
G
T
A
C
T
C
A
G
T
G
A
T
A
31250
A
A
T
G
G
A
T
T
A
A
A
A
A
A
T
A
T
T
C
A
G
A
A
A
T
G
T
A
T
T
G
G
G
G
G
G
T
G
G
A
G
G
A
G
A
A
T
A
A
G
31300
A
G
G
C
A
G
A
G
C
A
A
G
A
G
C
T
A
G
A
G
A
A
T
T
G
G
T
T
T
C
C
T
T
G
C
T
T
C
C
C
T
G
T
A
T
G
C
T
C
A
31350
G
A
A
A
A
C
A
T
T
G
A
T
T
T
G
A
G
C
A
T
A
G
A
C
G
C
A
G
A
G
A
C
T
G
A
A
A
A
A
A
A
A
A
T
T
T
A
C
T
T
31400
T
G
A
T
C
T
C
T
G
T
T
T
T
T
G
A
A
T
T
C
T
T
A
T
T
A
T
T
T
A
T
A
T
T
T
T
G
C
T
T
A
C
T
A
C
C
T
T
T
T
31450
T
T
G
C
C
T
T
T
T
G
T
C
C
T
T
T
T
G
T
G
G
A
G
A
G
G
G
C
G
A
T
G
A
A
T
T
A
A
G
A
G
T
A
G
T
G
G
G
G
T
31500
G
G
G
T
G
G
C
G
A
G
T
A
A
G
T
A
A
A
A
T
T
T
C
A
A
A
T
A
G
C
A
T
T
T
T
A
G
T
G
A
A
T
G
C
A
A
T
T
C
A
31550
G
T
A
G
T
C
C
T
G
A
A
G
C
C
T
G
A
C
T
T
A
A
T
A
A
A
A
C
A
A
A
A
T
T
C
A
T
T
T
A
T
G
G
T
T
G
T
T
T
C
31600 |
var(31595):[C:0.01]
A
T
G
A
A
A
G
T
T
A
T
T
A
G
A
T
A
G
G
A
T
C
A
A
G
T
T
T
T
G
T
T
T
G
T
A
T
A
T
T
G
T
T
T
G
C
C
T
T
G
31650 |
var(31646):[T:0.05]
C
T
C
T
G
G
T
T
T
T
G
C
T
T
T
T
G
T
G
C
T
T
A
G
G
C
A
A
G
T
G
C
A
A
A
A
T
A
C
T
C
T
A
T
G
G
A
A
A
T
31700 |
var(31656):[T:0.09]
C
A
T
A
A
T
T
G
T
C
A
T
C
T
T
C
T
T
C
A
T
G
G
T
G
T
T
A
G
G
G
A
T
A
T
A
T
T
G
T
C
A
C
A
T
G
A
T
T
T
31750
C
A
A
T
A
A
A
T
C
C
T
T
T
T
T
T
T
G
C
T
T
T
A
CATTTTG GAATATTTGT TATTTGAGCT
31800
TTTAAAAGAA GAA
T
ACAATG TTTAAGTCTG CCAGATGAAA TTCCAGTTAA
31850 |
var(31814):[C:0.09]
ACATCTTAGG CCCACACGAA GTTCCAGCCA GGAAGGAGCA AA
C
AGTTTTG
31900 |
var(31893):[G:0.20]
AGCCCGACTG AGCTTGCCCT GTGATCAAAT
G
C
A
A
T
C
C
C
A
G
T
C
T
T
A
C
A
G
C
T
31950 |
REPEAT
G
C
T
C
A
G
G
C
C
A
A
A
A
G
C
G
T
T
G
A
G
G
T
T
A
T
C
T
T
T
G
T
C
T
C
C
C
C
G
C
T
T
T
C
T
T
T
C
A
C
32000 |
var(31965):[T:0.01]
|
var(31988):[T:0.02]
A
T
C
A
T
A
T
A
T
A
T
T
C
A
A
T
G
C
A
C
C
A
A
T
A
A
A
T
T
C
T
A
T
T
G
A
T
C
T
A
C
C
T
C
C
A
A
A
A
T
32050
A
C
A
A
C
A
C
T
T
C
T
C
A
G
A
A
C
T
A
C
C
T
A
T
T
C
C
A
G
G
C
C
A
C
C
A
T
C
A
T
T
T
C
T
C
C
T
C
T
G
32100
G
A
T
G
G
T
C
A
C
T
A
T
G
G
T
T
A
C
C
T
C
A
T
T
G
G
T
G
T
C
C
C
C
G
C
T
C
T
G
C
T
T
G
C
C
T
C
C
C
T
32150
C
C
A
G
T
T
T
T
G
T
C
T
T
A
A
C
A
A
G
G
T
G
G
C
C
A
G
C
A
T
G
A
G
C
C
T
T
G
G
A
A
C
A
T
A
A
A
T
C
A
32200
G
A
T
C
A
T
G
T
C
A
C
T
T
T
C
C
T
G
C
T
C
T
A
A
A
A
C
C
G
C
C
A
A
T
A
G
C
T
T
C
C
C
A
T
C
T
C
A
T
A
32250
A
G
G
G
T
A
A
A
A
A
C
C
A
A
A
G
T
C
T
T
T
A
T
A
A
T
G
G
C
C
T
C
C
A
A
G
G
C
G
C
T
G
T
A
T
G
A
T
C
T
32300
G
T
T
T
C
C
T
T
T
C
C
T
C
A
T
A
A
T
C
T
C
C
C
A
G
G
C
C
T
C
A
C
T
C
C
C
T
A
A
T
T
C
T
C
A
C
C
T
T
C
32350 |
var(32346):[G:0.01]
C
T
C
A
C
T
C
T
T
C
T
C
C
A
G
C
A
C
A
C
A
G
A
C
C
C
C
T
T
G
C
T
T
G
C
C
C
T
C
A
A
A
T
A
C
A
A
A
T
G
32400
C
C
C
T
A
G
G
C
T
T
C
T
G
G
G
C
C
T
T
T
G
C
A
C
C
T
G
T
T
A
T
T
T
G
C
T
G
G
A
A
G
G
C
T
G
T
A
C
C
C
32450
C
C
A
G
G
T
T
T
C
C
A
T
A
G
A
T
T
C
A
C
T
T
C
C
T
C
A
C
C
T
C
T
G
T
C
A
G
A
T
C
T
T
T
G
C
T
G
G
A
A
32500
G
A
C
T
G
C
C
T
T
A
T
C
A
G
T
G
A
G
G
C
T
A
A
C
T
T
C
A
C
T
A
T
T
C
C
A
T
T
T
A
A
A
A
T
T
G
C
A
A
C
32550 |
var(32512):[T:0.15]
|
var(32520):[:0.01]
C
T
A
C
C
C
T
C
T
G
C
A
A
T
G
A
T
C
T
A
T
A
C
C
A
C
T
C
A
G
T
T
T
C
C
T
T
C
C
C
A
G
C
A
C
T
T
A
A
A
32600
T
C
A
C
C
T
G
A
C
A
T
G
C
T
G
T
A
G
T
T
A
C
T
T
G
T
T
G
A
C
C
T
T
G
T
T
T
A
T
T
G
T
T
T
A
T
C
T
T
C
32650
C
T
C
C
T
C
T
T
C
C
A
C
T
A
G
A
A
T
G
T
A
A
A
G
G
C
A
G
G
T
T
T
C
T
G
G
T
T
C
T
T
T
T
T
C
C
A
C
A
G
32700
C
C
A
T
A
T
C
T
T
C
A
T
T
A
T
C
T
A
T
A
A
C
A
G
A
A
C
T
T
G
G
T
A
C
C
T
A
G
C
C
G
A
C
A
A
T
T
A
G
T
32750
A
T
T
T
G
T
T
G
G
A
T
A
A
A
T
T
A
A
T
G AAGCAAGAGT AGAAGCACTG AGAGCATGAG
32800
GGGGTGGGTC AGGAGATCAG GAGTGAGGCT TTTCTGGTAA TTTCTTACAA
32850
CTTGCTGCCT CATCTT