IL12RB2 Color FASTA
The longest form of insertion/deletion sites is shown in the FASTA sequence and contain a '-' as the alternate allele in the variation tag.
*Display courtesy of
GeneSNPs
TTGAGAAACA TCCCCAACAT ATGTTTGGTT GTTTTTTTAT TTCCTTGAAA
50
AACATATGTA T
G
C
C
G
G
G
C
G
C
G
G
T
G
G
C
T
C
A
C
G
C
C
T
G
T
A
A
T
C
C
C
A
G
C
A
C
T
T
T
100 |
REPEAT
G
G
G
A
G
G
C
T
G
A
G
G
T
G
G
G
C
A
G
A
T
C
A
C
G
A
G
G
T
C
A
G
G
A
G
T
T
T
G
A
G
A
C
C
A
G
C
C
T
G
150 |
var(135):[A:0.13]
|
var(138):[C:0.39]
G
C
C
A
A
T
A
T
G
G
T
G
A
A
A
C
C
C
C
A
T
C
T
C
T
A
C
T
A
T
A
A
A
T
A
C
A
A
A
A
A
T
T
A
G
C
C
G
G
G
200 |
var(197):[A:0.12]
C
A
T
G
G
T
G
G
C
G
C
G
T
G
C
C
T
G
T
A
G
T
C
C
C
A
G
C
T
A
C
T
C
A
G
G
A
G
G
C
T
G
A
G
G
C
A
G
G
A
250
G
A
A
T
C
A
C
T
T
G
A
A
C
C
C
G
G
G
A
G
G
T
G
G
A
G
G
T
T
G
C
A
G
T
G
A
G
C
T
G
A
A
A
T
T
G
T
G
C
C
300
A
C
T
G
T
A
C
T
C
T
A
G
C
C
G
G
G
G
C
A
A
C
A
G
A
G
T
G
A
G
A
C
G
C
T
G
T
T
T
C
A
A
A
A
A
A
A
A
A
A
350 |
var(315):[A:0.01]
|
var(332):[T:0.01]
A
A
A
C
A
G
A
A
A
A
A
CATATGTAT ATTTATATGT GTGTATATAC ACACACACAC
400
ACACACATAT GCACACACAA ATATATAAAT TAAATTTTTA AATGAGATAG
450
AG
T
AAAATGC ATTTTTGAAA TTATTGATTT ATTAACAAAA CTAAAAGCCT
500 |
var(453):[C:0.01]
TCCTTCTCAC TAAAAAGTGT TGAAAA
A
T
C
C
A
T
G
A
A
T
T
A
T
G
C
A
A
G
A
T
T
G
T
T
550 |
REPEAT
A
T
A
A
C
A
T
T
T
G
G
C
T
A
T
C
A
T
A
A
T
C
T
T
A
T
T
C
T
T
G
A
T
A
T
C
A
A
T
C
A
G
T
T
T
T
T
A
A
A
600
G
T
A
A
T
G
A
G
A
A
G
C
T
G
C
T
G
C
A
T
T
T
T
T
A
T
A
T
T
T
T
T
T
A
A
C
A
A
A
T
G
G
A
T
T
T
A
A
A
A
650
T
C
C
A
C
T
G
A
A
C
T
G
C
T
C
A
A
T
T
A
A
A
A
G
A
T
T
G
A
A
A
C
A
A
A
A
T
A
G
C
A
A
A
T
T
G
T
T
T
C
700
C
G
A
G
T
T
T
T
T
A
A
A
AGCATTTT CTGTGATGAC AATCATAAAA TCTTCAGTAA
750
GAAAAACACA CAATAATGGG AACACTTCGA AATATTTGTT TTCAAATCGT
800
CTCTTCATAA CAACGTA
T
C
A
C
T
T
G
G
T
G
T
G
A
A
A
A
T
T
A
C
C
T
T
G
A
A
G
A
A
A
C
A
A
850 |
REPEAT
C
A
A
A
T
A
A
A
C
C
T
C
T
G
G
G
G
T
T
T
T
T
T
G
T
T
C
T
T
C
A
A
A
A
A
G
A
T
C
T
A
T
T
A
G
A
T
A
A
C
900
A
T
G
T
A
C
T
G
A
G
A
G
C
C
A
T
A
T
A
T
C
A
A
T
A
C
A
G
A
A
A
A
G
A
T
C
A
G
C
A
A
A
T
T
T
A
G
G
A
T
950
A
T
T
T
G
G
G
G
T
T
T
T
T
T
T
T
G
T
A
A
A
A
A
T
A
A
A
G
A
A
A
A
T
A
A
C
T
C
A
C
T
T
T
A
A
G
A
C
A
A
1000 |
var(966):[:0.88]
|
var(972):[G:0.27]
|
var(974):[C:0.12]
|
var(984):[G:0.27]
C
T
T
T
T
A
A
A
A
T
C
T
T
T
G
T
T
A
C
A
A
A
T
G
A
T
T
T
C
T
A
C
A
A
T
T
A
T
G
T
A
T
C
A
T
C
T
C
A
T
1050
T
A
C
A
A
A
G
T
A
A
T
A
T
T
A
A
G
A
T
T
C
T
A
G
A
T
T
C
T
A
C
G
A
T
T
T
A
A
A
A
G
A
T
T
T
T
A
G
T
A
1100 |
var(1084):[C:0.07]
A
A
A
T
T
A
T
T
C
A
T
G
T
A
G
A
T
A
A
A TTACTAAAGC ATGTAAACTA CAGTATGTCA
1150
CAATCCCATA AAGACAATCT A
C
T
G
T
A
C
A
T
T
G
T
T
G
A
T
T
C
C
A
A
G
A
T
G
T
A
C
A
T
1200 |
REPEAT
T
T
T
T
C
A
T
A
T
T
T
A
A
C
A
T
C
T
C
A
A
A
C
A
T
T
G
A
G
A
GCGGTTTTAA GGTAATGCCC
1250
AGAAGCGTGG TATGCAGTTG TCCACTTCTG CGGGCTCAGC AAACCTGTAC
1300
TGGGCTCAGT GGACTAGAAG AAAACTCCAG AGACAACGGG GTGGGGGAGG
1350
GGGGGGGACT TAAAAAAAAA TTCGATAGAT AATAT
A
C
A
T
A
T
G
T
T
T
A
A
A
A
T
1400 |
REPEAT
C
T
A
A
A
T
T
T
T
A
T
T
T
A
G
A
G
A
T
A
T
C
T
A
A
A
T
A
A
A
A
T
C
T
C
T
A
A
A
C
T
A
A
A
T
A
A
A
A
T
1450
T
T
T
A
G
T
T
T
A
A
A
A
G
A
T
T
C
T
A
A
A
T
G
T
T
G
A
G
A
A
A
G
C
A
T
T
G
T
T
A
T
T
G
T
T
T
A
C
C
T
1500
G
G
C
A
G
T
T
C
T
T
T
T
T
A
T
T
T
C
T
T
A
C
T
A
G
C
G
C
A
T
A
A
A
T
A
A
T
G
G
T
A
T
A
T
C
T
T
A
T
A
1550 |
var(1511):[:0.03]
|
var(1543):[G:0.26]
A
T
T
A
A
G
G
A
A
G
T
C
T
T
A
G
A
T
T
T
A
A
A
G
A
A
A
T
CT AAGCTGA
C
G
G
G
T
G
C
A
G
A
G
G
C
1600 |
REPEAT
T
C
A
G
G
C
C
T
G
T
A
T
T
C
C
C
T
G
C
A
C
T
T
T
G
G
G
A
A
G
C
C
A
A
G
G
C
G
G
G
A
G
G
A
T
T
G
C
T
T
1650
G
A
G
G
C
C
A
G
A
A
G
T
T
T
G
A
G
A
C
C
A
G
C
C
T
G
G
G
T
A
A
C
A
G
A
G
T
G
A
G
A
G
T
C
T
G
T
C
T
T
1700 |
NOT SCANNED
T
A
C
A
G
G
T
T
T
A
A
A
T
A
C
A
G
T
T
T
T
T
T
T
C
T
A
A
G
T
A
A
T
A
T
T
G
T
C
A
T
A
A
A
T
A
T
T
A
T
1750
G
T
C
A
T
G
A
A
T
A
T
T
A
T
G
C
A
G
A
G
C
T
G
C
C
G
A
C
C
C
C
T
C
T
G
T
A
C
T
C
T
G
G
G
C
A
G
T
T
T
1800
T
C
C
C
T
C
T
T
G
C
C
T
G
A
G
A
A
C
A
C
C
A
C
T
T
A
T
A
A
C
A
C
G
G
G
A
C
C
T
A
T
A
C
G
G
G
A
G
T
G
1850
G
T
G
A
C
A
C
G
C
C
A
T
C
T
G
T
T
C
A
A
G
T
T
T
A
A
C
T
T
T
T
T
T
C
T
C
A
T
T
T
T
T
T
A
G
A
C
A
G
C
1900
A
A
A
T
A
C
A
A
A
T
G
G
A
A
G
T
T
C
C
A
G
T
A
T
G
T
T
C
T
G
C
C
C
G
C
A
C
T
C
C
A
G
T
G
G
G
C
G
G
T
1950
C
T
T
G
T
G
C
A
C
A
G
C
C
C
A
C
T
T
G
G
G
A
G
G
C
C
T
C
G
G
C
G
C
T
C
A
G
G
T
G
T
G
G
T
A
A
G
A
G
C
2000
T
G
G
GCGG
T
G
C
A
G
A
G
C
A
C
A
G
A
G
A
A
A
G
G
A
C
A
T
C
T
G
C
G
A
G
G
A
A
A
G
T
T
C
C
C
T
G
A
2050 | Exon 1 |
UTR
T
G
G
C
T
G
T
C
A
A
C
A
A
A
G
T
G
C
C
A
C
G
T
C
T
C
T
A
T
G
G
C
T
G
T
G
A
A
C
G
C
T
G
A
G
C
A
C
A
C
2100
G
A
T
T
T
T
A
T
C
G
C
G
C
C
T
A
T
C
A
T
A
T
C
T
T
G
G
T
G
C
A
T
A
A
A
C
G
C
A
C
C
T
C
A
C
C
T
C
G
G
2150
T
C
A
A
C
C
C
T
T
G
C
T
C
C
G
T
C
T
T
A
T
G
A
G
A
C
A
G
G
C
T
T
T
A
T
T
A
T
C
C
G
C
A
T
T
T
T
A
T
A
2200 |
REPEAT
T
G
A
G
G
G
G
A
A
A
C
T
G
A
C
G
G
T
G
G
A
G
A
G
A
G
A
A
T
T
A
T
C
T
T
G
C
T
C
A
A
G
G
C
G
A
C
A
C
A
2250
G
C
A
G
A
G
C
C
C
A
C
A
G
G
T
G
G
C
A
G
A
A
T
C
C
C
A
C
C
C
G
A
G
C
C
C
G
C
T
T
C
G
A
C
C
C
G
C
G
G
2300 |
var(2292):[A:0.02]
G
G
T
G
G
A
A
A
C
C
A
C
G
G
G
C
G
C
C
C
G
C
C
C
G
G
C
T
G
C
G
C
T
T
C
C
A
G
A
G
C
T
G
A
A
C
T
G
A
G
2350 |
var(2312):[T:0.12]
A
A
G
C
G
A
G
T
C
C
T
C
T
C
C
G
C
C
C
T
G
C
G
G
C
C
A
C
C
G
C
C
C
A
G
C
C
C
C
G
A
C
C
C
C
C
G
C
C
C
2400
C
G
G
C
C
C
G
A
T
C
C
T
C
A
C
T
C
G
C
C
G
C
C
A
G
C
T
C
C
C
C
G
C
G
C
C
C
A
C
C
C
C
G
G
A
G
T
T
G
G
2450 |
var(2449):[T:0.06]
T
G
G
C
G
C
A
G
A
G
G
C
G
G
G
A
G
G
C
G
G
A
G
G
C
G
G
G
A
G
G
G
C
G
G
G
C
G
C
T
G
G
C
A
C
C
G
G
G
A
2500 |
NOT SCANNED
A
C
G
C
C
C
G
A
G
C
G
C
C
G
G
C
A
G
A
G
A
G
C
G
C
G
G
A
G
A
G
C
G
C
G
A
C
A
C
G
T
G
C
G
G
C
C
C
A
G
2550
A
G
C
A
C
C
G
G
G
G
C
C
A
C
C
C
G
G
T
C
C
C
C
G
C
A
G
G
C
C
C
G
G
G
A
C
C
G
C
G
C
C
C
G
C
T
G
G
C
A
2600
G
G
C
G
A
C
A
C
G
T
G
G
T
G
A
G
T
G
A
C
C
A
G
T
G
A
C
T
C
G
G
G
G
T
C
G
G
G
G
A
C
A
G
A
G
A
G
A
G
C
2650
C
C
C
A
G
G
A
T
C
C
C
G
G
A
C
C
A
G
C
G
G
G
G
T
G
T
C
T
G
C
G
T
G
C
C
C
G
G
G
A
T
T
C
C
G
T
G
T
C
T
2700
C
G
C
G
T
C
T
C
C
C
G
A
G
G
G
G
G
C
T
T
C
G
G
C
G
A
C
G
G
C
T
T
C
T
C
T
C
T
T
T
A
T
A
T
A
T
A
T
A
T
2750
A
T
G
T
A
T
A
T
A
T
A
T
A
T
T
T
T
T
A
A
A
G
T
C
T
T
C
C
A
A
T
A
C
G
A
T
C
C
G
A
A
A
T
G
G
C
T
T
C
T
2800
C
T
T
C
A
T
C
A
C
A GTCCTAACGC CCTGGGCACA GATGTTCACT TGGAGGTACT
2850
GGGTGGTGGT TTGGCTGGAT GGAGGGGAGG GAGCGCGCGG ACTGAGCCTC
2900
CAAGGTACTC TCTGGGCCGG GGCACAGAGT GGTGGGCTCA AACGGAAGGG
2950
AGGGGACGGC GACTGGAAAA GGGCAGAGGG CACCCCTGAG GGTCCAGCCT
3000
TGGTTCAGGC CCACAGACGT GGCTCCCGTT GCTTGAAAAT GTATCAAATG
3050
TGAGTAAGAT ATTGGGGGGG GCCTTCCGTA GTCCCGGATG AGGGTGAACT
3100
AACCTTGTCT CAGCAGTCTT TCCTGTGGCC TCTGGA
C
T
G
A
C
C
C
C
G
A
G
T
C
C
3150 |
REPEAT
C
T
G
C
C
T
G
G
C
C
A
G
T
T
A
C
T
A
G
C
A
A
G
A
T
G
C
T
C
T
G
G
T
G
C
A
A
G
C
A
A
A
T
T
G
G
C
C
A
G
3200
C
C
T
C
A
G
T
T
T
T
C
T
C
T
T
C
T
G
T
G
A
A
A
T
G
CCCCT TCCTTTGTGA ACTATGAGGC
3250
CCT
C
CTCATC TCCCTAGGAC ACACTAAATA TCAGTGTCAG CATTGTACGG
3300 |
var(3254):[T:0.28]
GATTATGTAT CTGTACCATT AGATCCAGGT CTTACAAATA GTAACCTAAA
3350
AGCATACAAA TAGACCTTGT CTAAGAACAG GGT
C
C
C
G
G
C
A
C
G
G
T
G
G
C
T
C
A
3400 |
REPEAT
|
var(3390):[G:0.01]
C
G
C
C
T
G
T
A
A
T
C
C
C
A
G
C
A
T
T
T
T
G
G
G
A
G
G
C
C
A
A
G
G
T
G
G
G
C
A
G
A
T
C
A
C
T
T
G
A
G
3450 |
var(3420):[C:0.08]
G
T
C
A
G
G
A
G
T
T
C
A
A
G
A
C
C
A
G
C
C
T
G
G
C
C
A
A
C
A
T
G
G
T
G
A
A
A
C
C
C
T
G
T
C
T
C
T
A
T
3500
T
A
A
A
A
A
T
A
C
G
A
A
A
A
T
T
A
G
C
T
G
G
G
C
A
T
G
A
T
G
A
C
G
C
A
C
A
C
C
T
G
T
A
A
T
C
C
C
A
G
3550
C
T
A
C
T
C
G
G
G
A
G
A
C
T
G
A
G
G
C
A
G
G
A
G
A
A
T
T
G
C
T
T
G
A
A
C
C
C
G
G
G
A
G
A
C
A
G
A
G
G
3600 |
var(3556):[T:0.15]
T
T
A
C
A
G
T
G
A
G
C
C
A
A
G
A
T
G
G
G
G
C
C
A
C
T
G
C
A
C
T
C
C
A
A
C
C
T
G
G
G
C
A
A
C
A
G
A
G
C
3650 |
var(3624):[G:0.38]
|
var(3650):[T:0.03]
G
A
G
A
C
T
C
T
G
T
C
T
T
A
A
A
A
A
T
A
A
A
T
A
C
A
T
A
C
A
T
A
C
A
T
A
T
A
C
A
T
A
T
A
T
A
T
A
T
A
3700 |
REPEAT
T
A
T
A
C
A
C
A
C
A
C
A
C
A
C
A
T
A
C
A
C
A
T
A
T
A
T
A
T
A
TAAAGAATAA AGCTAAATTA
3750
GTCCTTTTTT CCCCATTTTT AAAACTCTAG ATAATTGTTA TAATCTGCTA
3800
TGTGTGTGCT CTGTGTAGAT G
A
A
C
A
T
C
T
T
T
G
T
T
G
A
G
C
A
C
C
T
A
C
T
A
T
G
T
A
T
3850 |
REPEAT
T
T
G
G
T
T
T
T
T
G
G
A
T
A
T
A
T
A
T
T
A
T
C
T
A
A
T
T
C
C
T
T
A
A
A
A
A
C
A
T
G
G
T
G
A
A
A
T
T
G
3900
T
T
A
T
T
A
G
T
A
T
T
C
C
C
A
T
T
T
T
A
C
A
G
A
T
G
T
G
G
A
A
A
C
T
TACATG TTTCACACAG
3950
TTAGAGAGTT ACAGGTTTCT GGCTCAAAAC TGTGTTCCTT CTGTTTCCAC
4000
CTCTCTGGCT C
A
GAACCTTA TAACCACCTC CACTTGAACA AACAAACGTT
4050 |
var(4012):[T:0.03]
GGATTCTCAT TTTCCATTAA TAGGAATGGT ACAGTGCCCT ATTTCTCTGT
4100
CCAACACATA ACTAAAAGGA CCTTAGTGGC TAAGAGCTAA CACTTTCCTT
4150
CCCT
A
T
T
T
T
A
A
T
G
T
G
A
A
A
T
C
C
T
C
A
A
T
A
C
A
T
T
A
C
A
C
T
A
T
C
T
G
T
T
A
G
G
C
A
C
A
4200 |
NOT SCANNED
A
C
A
G
C
C
T
C
C
A
G
A
A
A
A
G
T
T
T
G
C
A
A
T
A
T
G
C
T
C
T
T
T
T
C
C
A
T
A
T
G
T
C
A
T
G
C
C
T
C
4250
T
T
G
A
A
T
G
T
C
A
T
G
T
T
C
A
T
T
A
C
A
T
A
G
G
C
T
G
A
T
A
A
A
T
T
C
C
C
A
A
A
C
T
T
T
G
A
C
A
A
4300
A
C
G
G
A
A
T
C
T
T
T
T
C
T
G
T
A
T
T
A
G
A
A
T
G
A
G
T
T
T
T
A
G
T
G
T
G
A
A
A
A
A
A
A
A
T
T
C
G
A
4350
A
A
G
C
A
C
A
C
A
T
G
T
A
A
T
T
T
T
T
A
A
G
G
T
A
G
A
A
G
A
A
T
C
C
G
C
C
A
A
G
T
A
C
A
G
T
A
G
G
T
4400
A
T
T
G
G
G
C
A
T
C
A
T
T
T
C
T
C
A
G
T
T
G
T
G
G
A
C
T
T
A
T
T
T
T
T
G
T
A
T
T
G
C
T
G
C
A
C
C
T
G
4450
C
T
T
T
G
T
T
C
T
C
T
A
C
C
A
A
A
T
T
A
T
T
T
G
T
C
A
T
C
T
T
T
G
T
A
A
T
T
A
C
G
C
T
C
A
C
A
G
C
A
4500
C
T
G
C
T
G
T
C
A
A
C
T
C
C
T
A
C
A
A
A
T
A
A
A
T
T
T
G
T
G
C
A
G
A
A
T
G
G
C
G
G
G
A
C
A
C
G
G
T
G
4550 |
REPEAT
T
C
T
C
A
T
A
C
C
T
G
T
A
A
T
C
C
C
A
G
C
A
C
T
T
T
G
G
G
A
G
G
C
C
G
A
G
G
T
G
G
G
G
G
G
A
T
C
A
C
4600
C
T
G
A
G
G
T
C
A
G
G
A
G
T
T
T
G
A
G
A
C
T
A
G
C
C
T
G
A
C
C
A
A
C
A
T
G
G
C
G
A
A
A
C
C
C
T
G
T
C
4650
T
C
T
A
C
T
G
A
A
A
A
C
A
C
A
A
A
A
A
T
T
A
G
C
G
G
G
G
C
A
T
G
G
T
G
G
C
A
C
A
C
A
C
C
A
T
G
T
G
G
4700
C
A
T
G
G
T
A
A
T
C
C
C
A
G
C
T
A
C
T
C
G
G
G
A
G
G
T
T
G
A
G
A
C
A
G
G
A
G
A
A
T
C
G
A
T
T
G
A
A
C
4750
C
C
G
G
G
A
G
G
C
A
G
A
G
G
T
T
G
C
A
G
T
G
A
G
C
A
G
A
G
A
T
C
A
C
G
C
C
A
C
T
G
C
A
C
T
C
C
A
G
C
4800
C
T
G
G
G
C
G
A
C
A
A
G
A
A
T
G
A
A
A
C
T
T
C
A
T
C
T
C
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
4850
A
A
A
G
C
C
A
A
A
T
C
C
C
A
A
A
G
G
A
A
G
T
C
T
T
A
T
A
C
A
A
T
T
T
C
C
T
T
T
G
C
C
C
T
T
G
G
A
A
G
4900
T
T
T
C
T
A
G
T
G
T
T
C
T
T
C
G
C
T
A
G
T
G
T
A
A
C
A
G
T
G
G
T
T
T
G
T
T
T
T
T
G
T
T
T
T
T
G
T
T
T
4950
T
C
C
A
A
A
T
A
A
G
T
A
T
T
G
A
A
C
A
T
G
T
A
C
A
T
T
A
T
G
G
T
C
A
G
T
G
C
A
T
T
T
G
C
T
G
G
A
C
T
5000
T
A
G
A
C
T
T
A
G
T
G
A
A
T
A
T
A
A
A
G
A
A
A
T
G
T
A
A
G
G
C
C
C
A
G
T
T
C
A
T
G
A
C
C
T
A
C
G
A
A
5050
G
T
C
A
A
A
A
T
T
G
T
T
T
G
G
G
A
A
A
A
T
T
T
T
G
A
G
A
A
T
A
C
T
T
A
A
T
A
T
G
T
C
T
T
A
A
A
T
G
A
5100
T
A
G
G
T
G
G
C
A
T
G
A
A
G
T
T
A
G
G
A
G
G
T
A
T
G
G
A
A
T
C
T
A
G
T
T
T
T
A
A
T
C
A
A
A
T
C
A
G
T
5150
C
T
T
T
C
A
G
T
G
T
T
A
A
A
T
C
A
G
A
T
G
A
A
T
G
G
G
C
A
A
A
G
A
G
A
G
G
A
G
T
C
A
A
A
A
G
C
A
A
G
5200
G
C
C
A
T
C
T
A
A
C
T
T
A
A
T
T
C
T
C
G
T
A
G
T
G
T
C
A
C
T
G
A
A
A
A
G
A
A
G
T
A
A
T
A
C
T
G
C
C
T
5250
T
T
T
T
T
C
T
T
A
T
A
A
T
A
A
T
A
G
C
A
G
G
T
A
A
C
A
T
T
G
A
T
T
G
A
G
C
T
C
T
T
G
C
T
A
T
A
T
A
C
5300 |
REPEAT
C
A
G
G
T
A
C
T
C
T
G
C
T
A
A
C
A
G
C
T
T
G
T
C
A
T
T
T
A
A
C
C
C
T
C
C
C
A
A
C
A
A
T
C
C
T
G
T
G
A
5350
G
A
T
A
G
G
T
G
C
T
G
G
T
T
T
T
T
T
G
T
T
T
G
T
T
T
G
T
T
T
T
T
T
G
T
T
T
T
T
G
A
G
A
C
G
G
A
G
T
C
5400 |
REPEAT
T
T
G
C
T
G
T
C
G
C
C
A
G
G
C
T
G
G
A
G
T
G
C
A
G
T
G
G
T
G
C
G
A
T
C
T
T
G
G
C
T
C
A
C
T
G
C
A
A
C
5450
C
T
C
T
G
C
C
T
C
C
C
G
G
G
T
T
C
A
G
G
T
G
A
T
T
C
T
C
C
T
G
C
C
T
C
A
G
C
C
T
C
C
C
A
A
A
T
A
G
C
5500
T
G
G
G
A
T
T
A
C
A
G
G
C
G
C
A
C
A
C
C
A
G
T
A
T
G
C
C
C
A
G
C
T
A
A
T
T
T
T
T
G
T
A
T
T
T
T
T
A
G
5550
T
A
C
A
G
A
C
G
G
A
G
T
T
T
C
A
C
C
A
T
G
T
T
G
G
T
T
A
G
G
A
T
G
G
T
C
T
C
G
A
T
C
T
C
T
T
G
A
C
C
5600
T
C
G
T
G
A
T
C
T
G
C
C
C
G
C
C
T
C
A
G
C
C
T
C
C
C
A
A
A
G
T
G
C
T
A
G
G
A
T
T
A
C
A
G
G
T
G
T
G
A
5650
G
T
C
A
C
C
A
C
G
T
C
C
G
T
C
C
A
G
T
A
G
G
T
G
C
T
G
T
T
T
G
T
A
T
T
C
C
C
T
T
T
T
T
A
C
A
G
A
T
G
5700 |
REPEAT
A
A
G
G
A
A
C
T
T
A
G
G
C
T
G
A
G
T
G
G
T
C
A
A
G
T
G
A
T
T
T
G
T
C
A
C
A
G
G
C
C
A
T
A
T
A
G
C
T
G
5750
G
A
A
T
T
A
T
C
C
G
A
G
C
C
A
A
G
A
C
T
T
A
G
G
T
G
T
C
C
T
G
G
G
C
G
G
A
T
C
C
A
C
T
G
C
T
C
T
T
T
5800
T
C
A
T
T
A
C
T
A
C
T
A
C
A
G
T
T
G
C
T
C
A
G
G
A
G
G
C
T
C
T
T
C
T
G
G
G
A
G
C
T
T
G
G
A
C
T
G
A
G
5850
G
T
G
A
T
G
A
G
C
G
T
A
A
A
C
A
T
G
G
T
T
C
A
A
T
G
C
C
T
C
T
T
G
G
A
G
G
T
A
G
T
A
G
C
T
T
T
G
T
G
5900
G
G
T
T
T
A
A
C
A
T
G
G
G
A
G
C
C
C
T
G
A
G
G
C
A
T
G
C
T
G
A
G
A
A
T
A
A
A
T
G
A
G
A
G
G
G
G
T
A
A
5950
G
C
C
T
G
T
T
C
C
T
G
C
A
G
A
A
T
T
T
A
A
A
C
C
G
A
T
A
G
A
A
G
A
G
G
G
A
A
A
G
C
A
G
T
T
A
G
A
C
T
6000
A
A
C
A
G
A
G
C
A
T
C
A
A
G
C
T
T
G
G
A
T
T
T
T
T
A
T
T
T
C
T
C
A
G
G
T
G
C
T
C
A
T
G
G
A
G
A
A
G
G
6050
G
A
A
G
C
A
T
A
G
A
A
T
G
T
A
A
T
T
C
G
A
A
T
C
C
A
A
T
T
C
T
G
G
A
T
T
T
A
T
G
T
G
T
G
G
T
T
T
T
T
6100
C
T
G
G
G
T
T
A
T
C
T
T
G
G
T
C
A
A
C
T
T
A
C
A
G
A
T
T
T
T
T
C
T
A
T
C
T
G
T
A
G
A
A
T
A
G
G
A
T
A
6150
C
T
A
A
T
C
A
T
T
A
C
T
T
T
A
T
G
T
A
T
T
T
G
A
C
C
A
A
A
T
A
T
T
A
A
C
A
A
C
T
A
A
A
T
T
A
T
A
T
G
6200
C
T
T
T
G
C
A
C
A
G
T
G
A
T
A
A
A
C
T
A
C
T
A
A
G
T
A
A
A
T
G
C
C
T
A
C
A
A
A
A
G
A
T
T
G
T
T
A
A
A
6250
A
T
T
A
G
A
A
T
C
T
T
A
A
T
T
A
A
C
C
T
C
T
A
T
T
T
T
G
C
A
A
T
G
A
T
A
T
G
C
A
G
G
A
A
A
A
G
C
A
A
6300
C
A
C
A
T
T
A
A
G
T
A
A
A
A
T
A
T
C
A
G
G
A
G
A
T
A
C
T
G
A
G
A
T
G
G
A
G
G
G
T
T
G
T
T
A
G
T
G
T
A
6350
G
A
G
A
C
T
T
C
A
G
C
T
G
A
A
T
T
C
T
T
A
A
T
T
T
A
T
A
T
G
A
G
A
A
A
C
C
T
G
G
G
G
A
A
A
C
A
T
T
G
6400
T
G
G
C
A
T
G
G
T
G
A
T
C
A
C
T
A
C
C
C
T
T
A
G
T
T
T
T
T
T
A
A
T
T
C
C
C
C
T
C
C
C
A
A
G
T
G
T
G
C
6450
C
T
C
C
A
A
T
T
A
T
C
T
T
A
A
G
A
T
A
A
T
T
G
T
G
A
A
A
T
T
C
T
T
A
G
A
A
A
A
T
T
C
T
C
A
A
A
A
C
A
6500
A
T
G
C
A
A
T
T
A
T
C
T
T
A
A
T
A
T
G
T
T
A
A
T
G
C
C
T
T
G
T
A
G
T
A
C
T
T
T
A
T
G
A
A
A
A
T
A
C
T
6550
C
A
G
T
G
G
T
T
G
C
T
T
A
C
A
A
G
G
T
G
A
A
G
C
A
A
A
A
C
T
T
G
G
C
C
A
G
G
A
C
T
T
T
G
C
A
A
T
A
C
6600
C
C
A
A
G
A
T
C
C
A
A
A
G
A
T
A
A
A
C
C
T
C
C
T
G
C
C
A
T
T
G
T
C
C
A
C
A
A
A
C
A
G
A
G
A
C
T
T
C
C
6650
A
G
A
T
T
G
A
G
G
A
T
G
T
C
A
A
A
G
A
A
A
A
A
A
C
C
T
T
T
C
C
A
A
T
A
C
A
C
T
A
A
G
G
A
A
G
A
A
A
A
6700
G
T
T
A
G
T
G
A
A
A
G
A
G
G
T
T
T
A
G
T
T
T
T
C
T
C
A
A
T
A
A
A
G
G
T
C
A
A
T
T
G
C
T
A
T
T
T
T
T
A
6750
A
A
A
T
A
A
G
G
A
A
A
G
G
A
G
G
C
T
T
T
G
A
A
G
T
A
T
G
A
A
G
T
T
A
C
C
T
G
C
C
A
T
G
G
T
G
A
C
A
G
6800
A
G
G
C
A
G
A
A
A
T
G
G
A
G
G
A
A
C
C
A
A
G
G
A
T
G
G
T
G
C
C
C
G
G
G
G
C
C
T
C
T
T
T
C
C
A
G
C
A
C
6850
A
T
C
A
T
C
C
T
T
C
C
C
A
A
T
A
G
A
A
G
A
C
A
G
C
T
T
A
T
T
T
T
A
T
C
G
A
T
A
G
G
C
C
T
A
G
C
A
G
G
6900
A
T
A
C
A
G
A
G
A
G
T
G
A
A
T
C
A
G
A
G
A
A
G
G
C
T
G
G
A
G
T
T
T
C
C
G
A
A
G
C
T
T
T
A
T
T
G
A
A
C
6950
A
C
T
T
G
C
C
A
T
G
A
A
A
G
T
T
T
T
A
G
G
C
T
T
A
T
G
G
G
A
G
C
T
A
T
T
C
A
A
A
G
A
A
A
G
A
A
A
A
G
7000
A
G
G
T
C
A
T
G
T
A
G
T
T
T
A
T
T
T
G
A
A
A
G
T
G
T
C
T
T
G
T
T
T
C
T
C
C
A
A
G
A
C
T
C
C
A
T
T
C
G
7050
T
A
T
C
T
T
G
T
T
T
C
T
T
T
C
T
T
T
C
T
T
T
T
T
A
C
T
G
T
T
A
T
A
T
T
G
G
A
G
A
A
A
T
G
C
T
T
G
T
T
7100
C
A
A
T
C
T
A
T
A
G
G
A
T
A
A
A
A
T
A
G
T
T
C
T
C
A
G
T
A
C
A
G
A
T
G
A
T
T
G
A
G
G
G
G
T
T
G
G
G
G
7150
T
G
G
G
A
T
A
A
A
T
T
C
A
T
T
T
C
A
A
C
T
C
T
G
A
T
T
T
G
T
T
T
A
C
G
C
A
C
A
A
C
A
T
T
T
C
A
G
G
A
7200
G
T
C
T
A
T
T
A
T
G
T
C
A
A
A
T
G
G
G
A
T
G
T
A
T
C
T
A
A
A
A
T
G
G
A
A
A
T
A
A
A
G
A
C
A
A
A
C
A
G
7250
A
A
T
T
G
A
C
A
G
A
A
A
C
A
A
C
A
T
T
C
C
A
G
A
A
A
A
A
A
T
A
G
G
A
A
A
A
G
A
A
G
A
G
A
G
A
A
A
A
G
7300
A
A
T
A
A
A
G
G
A
A
G
T
T
A
A
G
A
A
A
A
A
A
A
A
A
A
A
G
C
C
A
T
A
A
A
G
A
G
G
G
A
A
A
G
G
A
G
A
A
A
7350
A
C
A
C
A
T
T
G
A
A
T
T
T
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
G
G
A
A
C
A
A
A
A
A
T
T
C
G
G
A
A
G
T
C
T
C
7400
C
T
G
A
A
T
T
T
G
A
G
C
A
A
G
A
A
A
A
G
A
A
A
G
T
T
C
C
T
G
T
A
C
T
T
G
G
G
T
G
A
A
A
T
T
A
A
A
G
A
7450
G
G
A
A
C
C
A
T
A
G
G
A
C
A
G
C
A
A
A
T
G
C
T
T
A
C
C
A
A
T
G
A
A
A
T
T
A
G
A
G
A
A
A
A
T
T
C
C
A
G
7500
G
C
A
G
C
C
T
C
G
T
C
A
G
C
T
G
C
A
C
A
A
A
A
A
G
G
A
A
A
A
C
A
A
G
T
G
T
G
T
G
T
G
T
T
A
A
A
T
T
T
7550
G
G
C
T
C
A
T
G
T
A
A
A
C
A
G
T
G
C
T
T
G
G
A
C
T
A
T
T
G
A
A
T
A
G
A
A
A
G
A
A
G
A
A
A
A
A
G
T
A
G
7600
A
A
A
A
G
G
T
T
A
T
G
C
A
T
T
T
T
A
C
T
T
T
C
C
T
T
C
C
C
C
T
T
C
A
A
G
C
C
A
T
T
T
A
C
C
A
T
G
A
C
7650
A
T
T
A
T
G
A
A
T
G
G
G
G
C
C
G
G
T
T
T
G
A
T
G
A
T
G
G
G
G
C
C
T
G
A
T
A
G
A
C
G
G
G
C
T
T
T
T
G
C
7700
C
C
A
T
G
T
A
A
T
G
G
C
T
T
G
T
T
A
C
A
T
TCTTTCACC AAATGGTAGA CTTGGAATGA
7750
AAAACAGTTC ATT
T
TCATGA CCATAACTCA GGAAATTTCA TGAAGAAGAG
7800 |
var(7764):[G:0.05]
AAGGTTAGCT AATTGGTAAC TTGATTTGAT TATCCTTTTC CATCACCATA
7850
GTGGAATAGC ATC
C
A
T
A
G
T
A
G
T
G
G
A
A
T
AG
C
ATACGGTTAC ATATTGTAT
G
7900 |
var(7864):[:0.86]
|
var(7880):[:0.86]
|
var(7900):[A:0.04]
TGCGCTGAGT TTTGTTGTTT CATCCTCTTT TGAGGGAGGT GGGCCTCAGA
7950
AGTAATGAGT CAACCTTCTG AAGAGTAAAG CATTAGGCAT TATAAATGCT
8000
TTACTAGATA GATATCATAA AGATTGT
A
T
G
T
A
A
G
G
T
G
C
C
T
A
G
C
A
T
C
A
T
G
C
8050 |
REPEAT
|
var(8030):[A:0.01]
|
var(8047):[G:0.04]
C
T
G
A
A
A
C
A
T
A
G
T
A
A
G
A
G
A
T
C
A
A
A
A
A
A
T
TGC AGCATTAGTA TTAGTATAGT
8100
GTTAAGATTA GCATTATTTT TAGTATTATG CTGCTACTGT TGCTATTGAT
8150
TACAAGCAGC CTCACATCTA GAAGTGATGT T
G
G
A
T
T
A
G
A
A
A
T
C
A
G
G
A
G
A
C
8200 |
REPEAT
T
G
G
C
C
G
G
G
C
A
C
G
G
T
G
G
C
T
C
A
T
G
C
C
T
G
T
A
A
T
C
T
C
A
G
C
A
C
T
G
T
G
G
G
A
G
G
C
C
G
8250 |
REPEAT
|
var(8249):[T:0.01]
A
G
G
C
A
G
G
C
A
G
A
T
C
A
C
C
T
G
A
G
G
T
C
A
G
T
T
C
A
A
G
A
C
C
A
G
C
C
T
G
G
C
C
A
A
C
A
T
G
G
8300
T
A
A
A
A
C
C
C
C
A
T
C
T
C
T
A
C
T
A
A
A
A
A
T
A
C
A
A
A
A
A
T
T
A
G
C
T
A
G
C
C
A
G
G
T
G
T
G
G
T
8350
G
G
C
G
C
A
T
G
C
T
T
A
T
A
G
T
C
C
C
A
G
C
T
G
C
T
C
A
G
G
A
G
G
T
T
G
A
G
G
C
A
A
G
A
G
A
A
T
C
G
8400
C
T
T
G
A
A
C
C
C
A
G
G
A
G
G
T
G
G
A
G
G
T
T
G
C
A
G
T
G
A
T
C
C
A
A
G
A
T
G
G
T
G
C
C
A
T
T
G
C
A
8450
C
T
C
C
A
G
C
C
T
G
G
G
T
G
A
C
A
G
A
A
C
G
A
G
A
C
T
G
C
A
T
C
AGAGAGAA AGAGAGAGAG
8500 |
var(8462):[A:0.01]
AGAGAGA
C
T
G
A
G
G
T
T
C
T
G
A
T
C
T
G
G
A
T
T
T
T
G
C
T
A
T
T
A
A
T
G
T
G
A
A
C
T
T
G
A
G
C
8550 |
REPEAT
|
var(8530):[T:0.01]
|
var(8540):[:0.04]
A
A
G
T
C
C
C
C
T
C
T
T
T
T
T
T
T
C
T
A
G
G
T
C
A
C
G
G
T
G
A
T
C
C
A
T
T
T
G
T
A
A
A
G
T
C
G
G
G
A
8600
A
T
A
A
A
T
G
A
C
C
T
C
T
G
A
A
G
T
GT TGTCTGTATA TTGATCTGCT ACCAGTAAAA
8650
C
A
TATCTCTG TAAGTAGCTT TGCAGGCAGA AGGGAAGAAT TTTGTTCTTT
8700 |
var(8652):[G:0.38]
GCCTCATTTA GTCACCTGAT CATTAA
C
GAC ATTCATTTAT ATGACAACCA
8750 |
var(8727):[T:0.13]
GCCTTGAGGC ACACTTGAAA CAATCATTTG GTTGTCTGTG GTAGCCCAGA
8800
CTGAAATGTC AGCTGTTGGA GGGGAAGGGA GCAGCAGGGC ACAGTAGTTA
8850
CTAGTAACTC GTGT
A
GCTCC TTCCTCCCCT GACTTTTTAA
G
TTCTTTGAT
8900 |
var(8865):[G:0.06]
|
var(8891):[A:0.01]
GGTCTTAGGA ATTAAGATTT TTTTTACCTG GCCTAACAAA ACATACAACT
8950
CTAGTACACT GAAAATCATA TGTGATTTAG CAAAGAAATA CAAACGAGGG
9000
AATCAGCAGG GGA
A
A
T
A
G
G
A
A
C
C
A
G
C
C
T
C
A
G
T
G
G
G
G
T
T
C
T
T
A
C
T
T
T
G
T
G
C
9050 |
REPEAT
T
A
A
G
T
A
T
T
C
T
C
A
T
G
A
A
T
C
C
A
T
G
A
C
A
C
C
A
T
G
G
A
C
T
G
T
T
C
A
C
A
A
T
A
A
C
T
T
T
G
9100
C
C
T
T
A
A
T
C
G
T
C
A
C
C
G
T
A
A
C
T
T
T
G
T
C
G
A
G
C
T
A
G
G
T
A
T
T
A
C
T
A
T
A
C
C
T
A
C
T
G
9150
T
A
A
G
G
C
A
T
G
A
G
G
A
A
A
TGGTG CTCTCACAGT CAATAGCATA TAGCAGAACT
9200
GAGATTCATT CACCTTTTTC TTTTCCTTAA TACCACTATT TCCCTTGACC
9250
TTAATACAGT GCTACAGAAG AAAAATAATT TGGAAGTAGA AAGTTTTTCT
9300
GCCAACATGA GATTATCACC TGCGAAAGGA AACTTAAGAG TTTCTTTTTT
9350
CCTAGCCTAG CACAATACAA TTTTGAAGTA GCTTCATGCT TTGTGCTTCT
9400
CTCTAGAGCA ATGGGGAAAG AGGCTGGTCA GGGAGTAATT GTTGTCTCTG
9450
TCTTCCTACC GGTCGGTGTA TTTCTGGCTT GTTCCCGCCC ACCCCACCCC
9500
CATCCCCGAT CTGAGACGTT GTTTTCACCA TCTGGAAACT GTCACAACTT
9550
GAGTGATGAG TCAATGACAT AGCACACTCT TTGATTTTCT GATTCAAGAC
9600
AGAGTTGTTG TTTTAATATT TACCCTCTAG GCAGGGTATG TGAAGGATGT
9650
TTACAGTTAC AGTAGGTTTC ATTTTATTGG AAGATACCTC ATTTACTTGA
9700
AGGTCTTTGG GGATTCTGAA CTTCTCATAA AAGGAGAAGC TATTTTTACC
9750
TGGTAGTCAG AGAAAATGAG CAAGTTTGTG TTTGGATCAA TGTACCATTA
9800
TATAAACTCA AATTTATCTT CCATTTTACC TATTTCATAT AAATATGTAT
9850
GTTTATATAA TATACACATA TATTTTAAC
C
TATTTAATAA TAGGACATAA
9900 |
var(9880):[T:0.01]
TATATATGAA AACATATTTC ATATATATCC ATTTTTTTAA ATCCTTATAA
9950
TTATCATATG AGTATTTTAC TATTTGGAGA ATGTTATAGC TTCATAAATT
10000
TTGATCCATG TTGAAAATTT CTACAAAGGG GCGCCATAGA TATCTTTTGC
10050
AGTTAGGAAG CAGAAACCTA CTTAATCCCT ATGTAGCCAT TC
A
TTCAGTT
10100 |
var(10093):[G:0.18]
ATCTTCCAGT TCAATCCATA ATTTTATCTA TGCCAGAATA TTCCAAATTT
10150
TAATGCAGCA GCTAACATAG CTAC
T
A
T
A
G
G
G
G
T
A
G
A
A
A
A
A
C
T
C
C
G
C
T
C
C
A
10200 |
REPEAT
T
C
C
T
C
C
T
A
G
G
G
T
C
T
T
G
G
T
T
G
A
G
T
C
T
G
A
G
G
A
T
T
A
A
A
T
T
G
A
C
A
T
T
A
G
A
T
T
A
A
10250
C
A
G
G
A
A
A
A
A
A
A
T
A
A
T
A
C
A
A
A
T
T
T
A
C
T
C
A
A
C
A
A
A
T
A
T
T
A
T
G
G
G
A
C
A
T
G
G
G
A
10300 |
var(10261):[:0.01]
G
A
C
A
T
G
A
A
A
A
A
A
T
G
A
A
G
A
C
C
C
A
A
A
G
A
A
G
T
A
G
A
G
T
C
A
G
T
T
A
C
T
T
A
A
A
T
A
T
T
10350
G
G
A
T
T
G
A
G
C
A
A
A
G
A
A
T
A
G
T
A
A
C
C
T
A
T
A
A
A
A
A
T
G
T
G
A
C
T
A
A
A
T
T
A
T
G
T
G
G
G
10400
G
A
T
G
C
C
A
A
A
G
T
C
T
G
T
A
C
A
A
A
A
T
T
C
T
C
T
T
G
G
T
C
T
C
A
A
T
T
T
C
T
C
A
T
C
C
T
T
G
A
10450
A
G
A
T
A
A
A
G
A
T
G
T
T
G
T
T
G
A
C
T
T
T
C
T
A
G
T
A
C
A
G
G
G
A
G
T
G
T
C
T
T
T
C
A
T
A
T
G
G
G
10500
A
G
T
T
T
C
A
C
C
T
T
C
T
G
A
T
T
T
T
A
A
G
A
A
A
C
A
G
C
A
G
G
G
A
A
G
T
C
A
A
A
G
T
G
A
T
C
T
T
C
10550 |
var(10507):[G:0.12]
T
T
G
C
C
C
C
T
G
C
T
G
T
T
T
T
T
C
A
A
G
T
G
C
C
T
T
T
A
A
C
T
C
A
A
A
T
A
G
T
C
A
A
T
A
T
G
T
C
A
10600
G
A
A
G
A
G
T
A
T
A
T
T
T
T
AACACC TTTACTAATA TAACAAAAAA TCCAACCACA
10650 |
var(10614):[:0.23]
ATGT
A
GTAGA ATAAGATTTA ATGTAAGTAG TTTTAATGTA GTTGCATTAA
10700 |
var(10655):[G:0.02]
ACTAAACTAG AAGTAAAATA GATGAACATA CACACACAAT TTAAGTTTTA
10750
TCCAGGACAG CACATGCCTA CTATGTGCCA CAAATTGTG
G
C
C
T
C
T
G
C
C
C
C
10800 |
REPEAT
T
G
A
G
G
A
G
C
T
T
G
C
A
A
G
G
T
A
A
T
G
G
A
G
G
A
G
A
T
A
G
A
C
A
G
G
T
A
T
C
T
A
A
A
T
A
A
A
T
T
10850 |
var(10816):[C:0.01]
A
G
T
T
C
T
C
T
T
T
A
A
T
T
A
T
G
G
T
A
C
G
T
G
C
T
A
A
G
A
T
A
G
G
A
A
G
A
T
G CCAGGGTGCT
10900
CTGAGGATAC TGGCAGGAGG GTTCACTCTG ACCTGAAGAC ATAAGTAAGG
10950
CTTC
C
T
G
A
A
A
T
C
T
G
A
A
C
A
C
T
T
C
T
T
T
C
C
A
T
T
G
C
C
A
C
T
A
C
A
A
C
A
C
C
T
G
A
G
G
A
11000 |
NOT SCANNED
|
REPEAT
C
C
A
C
G
T
C
A
T
C
A
T
C
A
T
T
T
T
A
C
C
T
G
T
G
C
C
T
C
T
G
C
A
G
T
C
A
T
T
T
C
C
T
A
A
C
T
G
G
T
11050
C
T
G
C
C
T
G
C
A
T
C
C
A
C
C
C
T
A
G
T
C
C
C
C
A
G
A
G
T
A
G
T
G
T
G
T
G
T
G
T
G
T
G
T
G
T
G
T
G
T
11100
G
T
G
T
G
T
G
T
G
T
G
T
T
A
A
T
G
T
C
A
C
T
C
G
T
A
G
C
T
C
G
T
T
A
C
A
C
C
C
T
C
A
A
T
T
A
A
A
A
C
11150 |
REPEAT
T
C
A
A
T
T
A
A
A
A
T
A
A
G
T
A
A
A
A
T
T
C
C
T
A
A
T
T
A
A
A
C
A
C
C
A
G
T
G
G
T
T
T
C
C
C
A
T
A
C
11200
A
T
T
T
G
A
G
A
G
T
A
A
A
A
T
C
T
A
G
G
C
T
C
C
C
T
T
T
T
T
T
C
G
C
A
A
A
C
A
A
G
T
C
C
A
T
A
G
T
A
11250
A
A
T
C
T
G
G
C
T
C
C
T
G
A
T
G
T
C
T
T
C
T
C
T
A
A
T
T
T
C
A
T
C
A
C
A
T
A
C
C
A
T
T
C
T
C
C
C
T
G
11300
C
A
G
T
C
A
C
T
T
T
C
T
C
C
A
A
C
A
G
C
C
C
T
G
A
C
C
T
T
A
T
T
T
C
T
G
T
A
C
C
T
C
T
C
C
C
T
T
G
G
11350
C
A
A
G
C
T
C
G
T
T
C
C
T
C
T
G
C
C
T
C
C
A
G
G
C
T
G
T
G
C
A
T
T
C
A
C
C
A
T
T
C
C
T
C
T
G
T
G
A
G
11400
G
A
A
A
A
G
T
G
T
T
C
C
C
A
C
A
A
C
T
T
C
A
G
T
T
G
G
C
C
A
G
C
A
C
C
A
A
T
T
T
T
A
G
C
C
C
A
A
G
C
11450
T
T
C
G
C
C
T
C
C
T
G
C
A
A
A
C
G
C
C
T
T
T
G
T
T
G
A
C
A
A
G
T
T
T
C
T
A
T
C
C
T
C
C
C
C
A
G
G
G
T
11500
C
C
C
T
C
C
T
C
T
T
T
T
A
T
G
T
C
C
T
T
C
T
T
T
T
A
T
T
A
T
T
A
C
C
T
G
A
A
C
T
C
A
C
C
A
G
T
T
T
G
11550
T
T
G
C
T
T
A
T
A
T
T
T
T
T
G
T
T
T
T
T
T
G
C
C
T
G
T
C
T
A
C
T
C
C
A
G
G
A
T
G
T
T
G
T
T
T
C
C
A
T
11600
G
A
G
A
G
C
T
A
A
A
A
T
C
C
C
T
T
C
T
G
T
C
T
T
G
T
T
C
T
T
T
A
C
C
G
T
A
T
C
C
C
A
A
G
G
A
C
T
T
G
11650
G
C
A
C
T
T
A
G
C
A
G
C
T
G
C
T
T
A
A
T
A
C
A
T
A
T
T
T
A
T
T
G
A
A
T
G
A
A
T
A
A
C
T
G
A
A
T
G
A
A
11700
A
G
G
T
G
T
C
T
G
A
A
C
T
G
A
G
T
T
T
A
G
A
T
G
G
A
T
G
A
A
T
A
A
G
A
C
T
C
A
C
C
C
A
G
T
C
T
A
A
A
11750 |
REPEAT
A
A
T
A
G
T
G
G
G
A
A
A
G
T
A
A
A
G
A
G
A
A
T
A
G
C
A
T
G
A
A
G
G
G
A
A
G
A
C
A
C
A
G
A
G
G
C
A
T
G
11800
A
A
T
A
G
G
C
A
T
G
G
G
A
C
G
G
G
C
A
G
G
A
G
T
A
T
A
A
G
C
A
G
C
T
C
A
G
T
G
T
C
A
T
T
A
G
A
T
G
G
11850
T
A
G
T
G
T
C
A
G
C
A
G
A
G
A
G
T
G
G
T
G
G
A
T
G
T
G
G
C
T
G
G
T
G
A
T
A
A
A
G
A
C
A
G
A
A
A
T
T
A
11900
G
C
T
C
A
C
A
G
A
G
G
C
C
A
T
T
G
T
A
T
T
C
C
A
T
G
A
C
C
T
T
G
G
A
C
T
T
T
T
T
G
G
T
T
T
A
G
A
G
A
11950
C
A
G
G
G
A
G
A
C
C
T
G
C
A
G
A
T
T
T
T
G
G
C
T
T
A
A
A
T
C
T
G
T
G
C
T
T
C
T
C
A
A
A
C
A
T
T
T
T
A
12000
A
C
A
G
T
G
A
C
T
C
A
C
A
A
G
A
A
A
C
A
C
A
T
T
T
T
A
T
G
T
A
T
C
T
G
A
A
C
T
G
A
G
A
T
C
C
A
T
C
C
12050
C
C
A
G
C
T
T
T
T
A
G
A
A
G
C
T
G
T
C
A
C
A
T
T
C
A
T
T
G
G
C
T
C
G
T
G
G
C
T
C
C
T
T
C
C
A
C
C
A
C
12100 |
REPEAT
T
T
C
A
G
A
G
C
C
A
G
C
A
G
C
A
G
C
A
G
A
G
C
G
A
G
T
C
C
T
T
G
G
T
A
C
C
T
C
A
T
A
T
C
T
C
T
C
T
G
12150
A
C
C
C
A
C
T
C
T
C
C
T
G
C
C
T
T
T
C
T
T
G
T
A
C
A
C
T
T
T
T
A
A
G
G
G
C
T
C
C
T
G
T
G
A
C
T
A
T
A
12200
T
T
G
G
G
C
C
C
A
C
T
T
G
G
T
T
A
A
T
C
C
A
G
A
A
T
A
A
T
C
T
T
C
C
C
A
T
C
T
C
A
A
G
G
T
C
C
T
T
A
12250
A
C
T
T
T
A
A
T
C
A
C
G
T
C
T
C
C
A
A
A
G
T
G
T
C
T
T
T
G
C
C
A
T
G
T
A
G
G
G
T
A
A
C
C
T
G
T
T
C
A
12300
C
A
G
A
T
T
C
T
G
G
G
A
A
T
T
A
G
G
G
C
A
T
G
G
A
C
A
T
C
T
T
T
G
G
T
G
G
G
C
C
A
T
T
T
T
C
C
T
G
T
12350
C
T
A
C
C
A
C
A
G
G
G
A
T
G
T
T
T
A
T
A
G
G
G
A
G
T
T
T
T
C
T
A
A
A
G
A
T
C
A
T
A
T
T
C
C
T
T
T
C
C
12400
C
T
C
C
T
T
C
G
C
A
T
C
T
T
T
C
T
T
T
C
A
A
T
A
G
A
C
A
T
T
T
G
T
T
G
A
G
T
A
C
T
T
A
C
T
G
T
T
T
C
12450 |
REPEAT
C
C
A
G
T
G
T
T
A
A
G
T
G
C
T
G
G
T
A
T
T
C
A
A
C
A
G
T
G
A
G
C
A
A
G
G
T
A
G
T
C
A
A
T
G
T
T
C
C
T
12500
G
C
T
C
T
T
A
T
G
G
G
G
C
T
T
A
T
A
T
T
C
T
A
G
T
A
T
A
G
A
A
G
A
C
A
G
A
T
G
A
C
A
A
A
C
A
A
G
T
A
12550
A
T
T
A
A
G
T
A
A
A
G
G
A
A
T
A
A
G
G
C
A
G
T
T
A
C
A
G
A
T
T
G
T
G
C
C
A
T
G
A
A
G
A
C
A
G
T
A
A
T
12600
A
A
G
G
T
G
A
T
G
A
G
T
A
A
A
A
A
A
T
C
A
A
C
T
G
G
G
G
A
A
G
A
C
C
A
C
A
T
T
G
G
T
C
A
G
G
G
A
G
G
12650
G
C
G
T
C
G
G
A
G
G
G
A
T
A
G
A
G
A
C
A
G
T
G
G
T
C
A
G
G
G
A
G
G
G
G
C
T
G
T
C
T
G
G
G
G
A
A
G
T
A
12700
A
C
A
C
A
T
G
A
A
C
T
G
A
A
A
T
C
T
A
A
A
G
G
G
T
G
T
A
A
A
T
A
T
G
T
C
A
G
C
C
A
C
A
C
G
A
A
G
A
C
12750
G
C
A
A
G
G
G
A
A
G
A
G
G
A
T
T
C
T
A
G
C
A
G
A
G
G
A
C
A
T
G
G
A
A
A
A
T
G
C
A
A
A
G
T
C
C
T
C
T
A
12800
G
G
C
A
G
C
A
A
A
G
G
G
C
A
T
T
G
T
T
C
A
A
G
G
A
A
C
A
G
T
C
T
G
A
A
G
G
C
C
A
G
T
G
T
G
A
A
T
G
G
12850
A
G
C
A
G
A
G
T
G
A
A
C
C
A
G
G
C
A
A
A
A
A
T
G
T
A
A
G
C
G
A
T
G
A
T
G
G
C
A
A
G
A
T
G
G
G
A
A
G
A
12900
A
G
T
G
A
G
G
C
C
A
T
G
C
A
G
T
G
G
C
T
G
A
G
A
G
A
T
T
G
T
G
T
G
T
G
G
T
A
T
G
G
G
C
T
G
T
G
G
A
T
12950
A
T
T
T
T
T
C
T
A
A
C
A
G
C
A
G
T
A
G
G
G
A
C
C
C
G
T
T
G
A
A
G
G
G
T
T
T
C
C
A
A
T
A
G
T
G
G
T
G
G
13000
T
G
T
G
C
A
G
G
G
G
G
T
A
A
C
A
T
G
A
T
C
T
G
A
T
T
T
A
T
G
T
T
T
T
T
C
A
A
A
G
A
T
A
G
T
T
G
G
C
T
13050
C
T
G
T
G
A
A
A
A
T
G
G
C
T
T
A
G
A
A
A
G
G
G
C
A
A
G
G
A
T
G
G
T
T
T
G
G
A
A
A
G
A
C
A
T
G
T
T
G
A
13100
C
G
G
C
T
A
G
A
A
T
A
G
A
C
T
A
G
G
G
G
A
G
A
G
A
T
G
A
C
A
G
T
G
G
T
T
T
G
G
A
C
T
A
G
G
G
T
G
A
G
13150
G
G
G
A
C
A
G
T
T
G
G
A
A
T
G
G
A
G
A
G
A
A
G
T
G
C
A
T
T
G
A
T
C
T
G
T
A
A
C
A
T
A
T
T
T
T
G
G
A
G
13200
G
T
A
A
A
G
T
T
G
A
T
G
G
G
A
C
T
A
G
A
G
A
T
G
G
T
T
T
A
G
C
T
G
T
A
G
G
A
G
A
T
G
A
G
A
A
A
A
A
G
13250
G
T
T
A
G
A
A
T
C
A
A
A
G
A
T
G
A
C
T
T
C
T
A
G
G
T
G
T
T
T
T
T
A
G
C
C
A
C
C
T
G
G
G
G
T
A
A
G
A
A
13300
T
A
T
C
A
T
T
C
G
C
T
G
A
G
A
T
A
G
A
A
A
A
G
G
C
T
G
A
A
G
G
A
A
G
A
A
T
G
A
A
T
T
T
G
G
A
G
A
A
A
13350
G
G
G
T
G
C
C
A
A
G
A
A
T
T
T
A
A
A
C
T
G
A
A
C
A
C
C
T
T
A
A
T
A
T
T
G
A
G
A
A
T
C
T
G
T
T
A
G
A
C
13400
A
T
C
T
A
A
G
A
G
G
T
A
A
T
G
C
C
A
A
G
G
A
G
A
C
A
G
A
T
G
G
A
T
G
A
G
A
C
T
G
G
A
G
C
T
C
A
G
G
G
13450
G
G
A
T
G
T
G
T
G
A
G
T
T
G
A
T
C
T
A
C
T
C
T
G
A
A
A
T
C
T
T
T
A
G
C
T
A
G
C
A
G
A
T
G
A
C
A
T
C
T
13500
A
G
A
G
C
T
A
G
G
G
G
A
C
C
A
G
G
T
G
A
A
A
T
C
C
C
C
T
A
C
A
G
A
G
A
A
A
G
T
A
G
A
A
A
T
G
G
A
A
A
13550
A
A
A
A
A
A
A
A
A
T
A
C
C
T
T
G
A
G
T
G
A
G
C
T
A
A
G
G
T
C
C
T
C
C
A
A
G
A
G
T
T
A
A
A
A
A
T
C
A
A
13600
G
A
G
G
A
A
A
A
C
A
A
A
G
A
G
T
A
G
C
C
A
G
C
A
A
A
G
A
C
T
T
A
T
G
C
T
A
A
C
A
T
T
A
T
T
T
A
G
G
G
13650
T
T
T
T
C
C
T
G
A
A
T
G
A
T
G
G
C
T
A
G
G
C
T
A
G
A
G
G
T
A
G
A
G
G
A
A
A
C
A
A
A
G
G
G
C
G
C
T
T
T
13700
C
C
T
A
G
A
A
C
C
C
C
A
C
A
G
G
G
A
C
A
G
G
A
G
T
G
C
T
T
T
G
T
C
T
C
T
A
G
C
A
C
T
T
A
G
T
G
T
G
C
13750 |
REPEAT
C
T
A
G
C
A
C
A
T
G
A
A
A
G
G
C
A
G
C
C
A
T
C
C
A
T
A
T
T
G
A
A
T
G
A
A
T
A
A
G
T
G
A
A
A
T
T
T
T
C
13800
T
G
A
A
G
C
T
C
T
T
C
A
A
T
A
T
T
T
T
C
T
G
G
C
A
T
A
T
G
T
C
T
A
G
G
T
A
T
G
G
G
G
T
T
A
A
G
A
G
G
13850
T
A
A
A
C
T
T
T
T
G
C
T
T
T
G
C
A
C
T
G
A
C
T
A
C
T
T
T
T
T
A
G
T
G
G
C
C
T
G
A
C
A
T
C
A
C
A
G
A
A
13900
C
T
T
C
C
C
A
G
C
C
T
A
C
T
T
T
A
T
G
A
A
T
T
T
T
T
G
G
C
C
T
A
T
C
T
T
T
A
A
T
A
G
A
ATTTAAA
13950
GAATTTGTTA CTGACCAGTA GAGCCATTCC TTGGGTTTGA ATTTGAAACA
14000
GATCAGAAAT TGCCAGCTTA TGTTTTCTGA CCTATTCAAG ATAAAATCAT
14050
TCTGTAAAAT AAGTAATTAA AAAACAAATA AGTAAACAAG CTTCTCTACA
14100
AAACCCAAAC AACCCTTGGA ATTCCTTTTT TACTGCCAAA GAGATCAATC
14150
TTTTACTAAG TTCCAGATGG GTTATGAGCC ATTTTTCGAT CTACTGATTC
14200
CAGAATCACT TGACTGGATC AGAAACTCTC ACTGGTCAAA CTACTCTGTA
14250
TGGTATGATG ATGAAGCCTT GTTTAGAAGG AAAAGAAAAA GAAAAGTGTT
14300
GTGTGGG
A
C
T
A
A
G
T
C
T
C
A
G
A
C
A
G
G
T
T
A
A
G
C
A
A
C
T
T
G
C
A
C
A
T
G
G
T
C
T
C
A
AG
14350 |
REPEAT
TATTTAAACC CAGTTCTAAA GGACCCCAAA GCCTAT
T
G
C
T
G
T
G
G
T
C
T
G
A
A
14400 |
REPEAT
T
G
T
T
T
A
T
G
T
C
C
C
C
C
T
C
A
A
A
T
T
T
A
T
A
T
G
T
T
A
A
A
A
T
C
C
T
A
A
C
T
C
T
C
A
A
G
G
T
G
14450
A
T
G
A
T
A
T
T
A
G
G
A
G
A
T
G
G
G
G
T
C
T
T
T
G
G
G
A
G
G
T
G
A
T
T
G
G
G
T
C
A
T
G
A
A
G
G
T
A
G
14500
A
A
T
T
T
T
T
A
C
G
A
A
T
G
G
A
A
C
T
A
G
T
G
A
C
C
T
T
A
T
A
A
A
A
G
A
G
A
T
C
C
C
A
G
A
G
A
G
C
T
14550
C
C
G
T
T
G
T
C
C
C
T
T
C
C
A
C
C
A
T
G
T
G
A
G
G
T
C
G
C
A
G
C
A
A
G
A
A
G
G
C
C
C
C
A
T
C
T
A
T
G
14600
A
A
C
C
G
T
C
T
A
T
G
A
A
G
T
G
G
A
C
C
C
T
C
A
C
C
A
G
A
C
C
C
T
G
A
A
T
C
T
G
C
T
G
A
C
C
T
C
T
T
14650 |
var(14643):[A:0.03]
G
A
T
C
T
T
G
A
A
C
T
T
G
C
C
A
G
T
C
C
C
C
A
G
A
A
C
T
G
T
G
A
G
A
A
A
C
A
A
A
T
T
T
C
T
G
A
T
G
T
14700
T
T
A
T
T
A
C
C
T
A
C
C
C
A
G
G
T
C
A
T
G
G
T
A
T
T
T
T
G
T
T
A
C
A
G
C
A
G
C
C
C
A
A
A
T
G
A
A
C
T
14750
A
A
G
A
C
A
TCCA AATTCCTTCT CTAATCCTTT GCTGACCCCA AGAAGTCTCA
14800
CTGAGATGGG ATTTGGAAGG TGGCTAAGAT ATTCGATTTA CTAGTTTTAA
14850
AGGTACATGT CATTTTTTAA AATAACAAGA TCTCAACAAG GTGGAGAAAA
14900
ATAAAGCGGC ACTTGAAGCT CTTCTGAGCT ATTTTGGCTC TGGTATTTTC
14950
TGAACATATT TAACATGAAT GAATTTGTCT TCTTTTGCAA G
G
A
A
G
A
A
T
A
C
15000 | Exon 2 |
UTR
G
G
A
G
T
T
C
T
A
T
A
C
C
A
G
A
G
T
T
G
A
T
T
G
T
T
G
A
T
G
G
C
A
C
A
T
A
C
T
T
T
T
A
G
A
G
G
A
T
G
15050
M A H T F R G C 8
C
T
C
A
T
T
G
G
C
A
T
T
T
A
T
G
T
T
T
A
T
A
A
T
C
A
C
G
T
G
G
C
T
G
T
T
G
A
T
T
A
A
A
G
C
A
A
A
A
A
15100 |
var(15064):[G:0.02]
S L A F M F I I T W L L I K A K 24
T
A
G
GTAAGAT ATTTCTGTAA GTTACTCTGT GGAAGAATTT GTGGTTTAAA
15150
I 25
TTCTCAGTTA CAGATGAAGT ATGTATTTGT GGTAAATGTT CTGGTAGTTG
15200
GTCTTTTGTA GTCAATCTCT GTCATTTAAG TGGATAAGT
C
TGGTTCTGTC
15250 |
var(15240):[G:0.01]
TATAACTAAT AGTTATTTTA TTTAATTTGC ACTAATGATT AATATAAGGG
15300
TCCAATTATT TTATTTCTTC CTAAGAAAGT GGCTTGGTAA CCCAGCTAGG
15350
CATCACAAAT ACATGTTTTA CATTTCAGCA CATTTTTCTT TTTTTTC
T
T
T
15400 |
REPEAT
T
C
T
T
T
T
T
T
T
T
A
T
T
A
T
A
C
T
T
T
A
A
G
T
T
C
T
G
G
G
A
T
A
C
A
T
G
T
G
C
A
G
A
A
T
G
T
G
C
A
15450
G
G
T
T
C
G
T
T
A
C
A
T
A
G
G
T
A
T
A
C
A
T
T
G
T
G
C
C
A
T
G
G
T
G
G
T
T
T
G
C
T
G
C
A
C
C
C
A
T
C
15500
A
A
C
C
C
G
T
C
A
A
C
T
A
C
A
T
T
A
G
G
T
A
T
T
T
C
T
C
C
T
A
A
T
G
C
T
A
T
C
C
C
T
C
C
C
C
C
A
G
C
15550
C
C
C
C
A
C
C
C
C
A
T
G
A
C
A
G
G
C
C
C
T
G
G
T
T
C
G
T
G
A
T
G
C
C
C
A
C
C
C
C
C
A
C
C
C
C
C
G
T
G
15600
T
C
C
A
T
G
T
G
T
T
C
T
C
A
T
T
G
T
T
C
A
A
C
T
C
C
C
A
C
T
T
A
A
G
A
G
T
G
A
G
A
A
C
A
T
C
C
G
C
T
15650
G
T
T
T
G
G
T
T
T
T
C
T
G
T
T
C
T
T
G
T
G
T
T
G
G
T
T
T
G
T
T
C
A
G
CACG
T
T TTT
T
CTTCCT
15700 |
var(15689):[G:0.02]
|
var(15694):[:0.99]
GCCTCCCGCC GTCCACAAGT TTGG
T
T
T
G
T
T
T
T
T
T
T
T
T
T
C
T
G
A
G
A
C
A
G
G
G
T
15750 |
REPEAT
C
T
G
G
C
T
C
T
G
T
T
G
C
C
C
A
G
G
C
T
G
G
A
G
T
G
T
A
G
T
A
G
C
A
C
A
A
T
GT TTGCAATACT
15800
TTTTTAATAC TCTTTTAAAA CTGTCTTTTT TTTCTTGGTA CAAGTATTTA
15850
AGTAAAAATT ATAAATCATA AATGGTGA
C
G GAAACAAATG TGTTTTTTTC
15900 |
var(15879):[T:0.13]
TGGGAAGGCT TTAGTAGTCT GGTAAATAAT TTGCATATAA GAGAGGCTGG
15950
TTTTTCCC
G
G AACTGTGTTC CTGAATGTTC TTCCAATCCT GCTTTCTAAC
16000 |
var(15959):[A:0.02]
CACTTTCCTG GTTATAGTTC TGATTATAGT ATTACTGTTA TGAGACGGAT
16050
GCATATTTTC ATTCAAATAC AGTTAGACTT CAATATGTTT ACCTTCTGTT
16100
TTCATTGTAC ATCACCATTA TAACCAGAGA CATGTAGGTT AATTATATTT
16150
GCATGATCTG ATGGAGTTAA TTTTACCCTG TTTTGGGGAA TTACATAAAC
16200
TCTTCATTTT GAAATGGGTT TATTATCACC AACTAAATAT TGCATCTGTA
16250
TCTTATTGCA G
A
T
G
C
G
T
G
C
A
A
G
A
G
A
G
G
C
G
A
T
G
T
G
A
C
T
G
T
G
A
A
G
C
C
T
T
C
C
C
16300 | Exon 3 |
var(16263):[C:0.11]
|
var(16299):[G:0.01]
D A C K R G D V T V K P S 38
A
T
G
T
A
A
T
T
T
T
A
C
T
T
G
G
A
T
C
C
A
C
T
G
T
C
A
A
T
A
T
T
A
C
A
T
G
C
T
C
T
T
T
G
A
A
G
C
C
C
16350
H V I L L G S T V N I T C S L K P 55
A
G
A
C
A
A
G
G
C
T
G
C
T
T
T
C
A
C
T
A
T
T
C
C
A
G
A
C
G
T
A
A
C
A
A
G
T
T
A
A
T
C
C
T
G
T
A
C
A
A
16400
R Q G C F H Y S R R N K L I L Y K 72
G
T
T
T
G
A
C
A
G
A
A
G
A
A
T
C
A
A
T
T
T
T
C
A
C
C
A
T
G
G
C
C
A
C
T
C
C
C
T
C
A
A
T
T
C
T
C
A
A
G
16450
F D R R I N F H H G H S L N S Q 88
T
C
A
C
A
G
G
T
C
T
T
C
C
C
C
T
T
G
G
T
A
C
A
A
C
C
T
T
G
T
T
T
G
T
C
T
G
C
A
A
A
C
T
G
G
C
C
T
G
T
16500
V T G L P L G T T L F V C K L A C 105
A
T
C
A
A
T
A
G
T
G
A
T
G
A
A
A
T
T
C
A
A
A
T
A
T
G
T
G
G
A
G
C
A
G
A
G
A
T
C
T
T
C
G
T
T
G
G
T
G
G
16550
I N S D E I Q I C G A E I F V G 121
TGAGCATTCC ATTTTGAATT TTTAAAACTT GGTGATCTTT TGGTATTTTT
16600
GATCTTTTGG TATTTGGTGT TAAACAGAAA CCCAAATACA GGTTAATGTT
16650
CTTTCTTTTC CCACCAC
A
T
T
GAAGTATTTT ATCTTGATAC C
G
ACCTGAGA
16700 |
var(16668):[T:0.15]
|
var(16670):[C:0.11]
|
var(16692):[A:0.12]
GCTTCAATGT GAGTTCAGAA ACTGGAATCT TATTTGGCAA GTCTCTCTCT
16750
CTCTCTCTCT CGCCATTAAA ACCATTTATC TGTTGTCCTT AACTCCAGTG
16800
GCAGAAAAAA TGGATCTCTG CAGGTGGGTC TTTATGCTTT TTTGACTTAG
16850
GAGAATATGT TTAAAGCTAC AGCCTCCTAA AAAGAAAGAA GAGATGTCTT
16900
TTTAGACTTA TGCAGCCCAG GATGACTACA CAGAGTTGAA CAGCACCTCT
16950
C
G
TCCTATCT AACTTAATGC CTCCCAAAAT AGTTCTTCCA TCCATGCTCA
17000 |
var(16952):[A:0.01]
CCCGGACCAC TGGTTCTCAT ACTTAACAGA AGGTAAAAGA AAACATTGAT
17050
CATACTTACT ATCTTTTCCT CAGTTCTCTA GGAAACTGAC TCCAGCAAAA
17100
AAAAAAAAAA AAAAAAAAAA TCTGCTAACA ATTCATGGGA AGGGGGCATG
17150
GGGCAGAGGA GTTACACAGC CCCAGGGAGG CAAGAGGGAA GGAGTGAGCC
17200
AGGAAAGGGA CAAAAGCAAA TGCCAGGTGG TAACATCACT GGACTGGCCA
17250
CAGCTTCAAC AGAAAATGCA GCTGGTTGTT TATACACTTA GGGACATTCC
17300
CAGAAAGAGC ATATAGAAAT CTCATGACGA GAGAAAGAAA GAAGAACTTA
17350
ACTATCTCCC ACTGGCCAAA GTCCACCTGA CGGGGGCTCA GTTTCCCACA
17400
CTGCTGACTT GCATTGCTGG TCCCTTCAGG CAGCTGCT
G
G
G
G
G
A
T
T
A
G
A
A
17450 |
NOT SCANNED
C
T
A
A
A
G
T
G
T
C
A
G
A
G
T
T
G
A
C
A
T
C
T
G
C
A
G
C
A
T
G
A
G
C
C
A
C
A
G
T
G
C
A
C
A
G
G
A
T
G
17500
A
A
C
C
A
G
C
A
G
C
C
A
G
C
A
G
C
A
C
A
C
C
T
A
C
C
T
G
C
A
G
T
T
C
G
C
A
A
C
C
T
G
T
G
G
C
C
C
A
T
17550
A
G
C
C
T
T
G
C
A
G
G
T
C
C
A
A
C
C
A
G
G
C
A
A
T
C
C
T
A
T
A
A
G
C
A
A
G
C
A
T
G
G
G
C
C
C
T
G
A
G
17600
G
G
A
T
T
C
C
A
T
G
G
C
A
C
C
C
T
G
T
G
C
C
T
C
A
G
T
G
G
T
T
C
C
A
A
G
G
A
A
G
C
T
T
T
G
G
C
G
T
G
17650
G
C
A
G
A
C
A
A
G
A
G
T
C
A
T
G
A
A
G
A
G
A
C
T
A
G
G
A
A
G
A
A
T
T
G
C
T
C
T
A
G
C
A
G
G
C
T
G
G
C
17700
T
G
A
C
C
A
A
G
C
C
T
C
A
T
A
G
A
C
A
T
C
A
T
C
T
C
T
G
T
C
A
T
A
A
A
G
G
C
A
G
T
G
A
T
A
T
A
G
A
G
17750
C
T
C
A
A
T
G
A
G
A
C
T
C
T
G
T
C
C
A
G
G
A
A
A
G
A
T
G
G
A
A
A
C
C
T
C
C
T
C
T
C
T
G
T
G
A
C
C
T
A
17800
T
A
A
G
G
A
T
A
T
A
T
A
T
A
T
A
T
A
G
T
T
G
G
T
G
C
C
A
G
G
T
G
A
T
T
T
T
C
C
T
G
G
A
G
G
G
C
C
A
C
17850
C
A
G
A
A
G
C
A
C
G
G
A
G
C
A
G
A
A
G
A
C
C
A
A
G
C
A
A
A
T
G
G
C
C
A
A
G
C
A
G
A
T
C
A
T
T
G
G
T
A
17900
G
G
A
A
G
G
A
G
G
T
A
T
A
A
A
C
T
A
G
G
C
C
A
A
G
T
A
C
T
C
A
C
C
T
T
C
C
A
G
C
T
C
A
G
G
G
C
C
T
C
17950
C
T
G
T
T
C
A
C
A
C
C
A
C
T
G
T
G
A
G
T
C
A
T
A
T
A
C
T
C
T
C
A
G
C
A
T
T
G
A
C
A
G
C
C
T
G
C
G
G
T
18000
A
T
A
G
T
A
G
A
A
G
T
A
G
C
A
T
G
G
G
C
T
T
T
G
A
A
T
C
T
C
A
A
C
T
C
T
G
C
C
A
G
T
G
G
C
A
G
T
G
T
18050 |
REPEAT
A
C
T
T
T
A
G
A
C
A
A
C
T
T
A
A
A
T
T
A
T
C
T
G
A
G
C
C
T
C
A
G
T
T
T
C
T
C
C
A
T
C
T
G
T
A
T
T
A
C
18100
G
A
A
G
A
T
A
A
T
A
A
C
A
T
C
T
A
C
C
T
C
A
T
G
A
A
A
T
G
G
T
C
A
T
A
G
T
A
A
T
T
A
G
A
A
G
A
C
C
T
18150
C
T
T
A
T
A
T
G
C
A
A
A
G
T
G
C
T
T
A
A
T
C
C
C
A
T
A
C
A
A
G
G
C
A
C
A
T
G
G
G
A
G
G
C
A
T
T
C
A
G
18200
G
T
G
A
C
G
G
C
T
T
T
A
G
G
C
T
T
C
T
C
A
A
C
A
G
C
A
A
C
C
T
G
G
A
A
T
G
T
G
G
G
A
G
G
C
A
A
C
A
A
18250 |
REPEAT
G
A
G
T
C
C
T
G
A
C
T
A
C
A
A
A
C
T
C
T
T
T
T
C
A
A
C
T
T
A
G
A
A
T
T
C
T
A
T
A
C
T
C
A
A
A
G
T
A
T
18300
C
A
G
T
C
A
A
A
C
G
T
G
A
G
G
G
T
A
G
A
A
T
A
A
A
G
A
C
A
T
T
T
T
A
A
A
C
T
A
T
G
C
T
C
A
A
A
A
T
A
18350
T
T
T
C
C
T
C
G
C
A
T
G
C
A
C
C
C
T
T
T
C
C
C
A
G
G
G
A
A
C
T
A
C
T
G
G
A
G
G
C
T
A
T
G
C
T
C
C
A
C
18400
C
A
A
C
C
C
A
A
G
T
A
A
T
T
A
G
A
C
A
A
G
A
A
G
G
A
A
T
A
A
A
A
C
A
T
T
A
A
A
T
C
T
A
A
G
A
A
A
C
A
18450
A
G
A
C
A
G
C
C
A
A
A
G
G
A
A
A
A
A
C
A
G
A
A
G
G
A
A
C
T
T
A
G
G
A
G
A
C
A
T
T
G
A
G
G
A
T
G
A
G
C
18500
A
G
T
C
C
C
A
G
A
A
T
G
A
C
A
G
C
T
G
G
G
T
A
C
C
A
G
G
C
A
T
G
G
A
G
A
C
A
A
C
C
T
G
T
C
T
T
A
T
A
18550
T
T
G
G
A
A
A
A
T
T
C
A
C
A
A
G
G
C
T
C
C
A
A
G
A
G
A
G
A
T
C
C
T
C
A
A
G
C
A
G
A
T
G
A
A
A
T
G
G
A
18600
T
A
G
A
A
G
T
C
C
C
A
A
T
A
C
A
T
T
G
C
A
G
T
A
T
A
T
T
G
A
A
C
A
G
T
G
A
T
T
C
A
G
A
T
A
A
T
T
G
G
18650
C
T
T
G
C
A
A
G
T
T
T
G
A
A
A
T
T
T
T
A
T
T
A
A
C
A
A
G
A
A
A
A
C
T
A
A
A
C
A
A
A
T
G
G
A
A
A
A
A
C
18700
A
A
G
A
T
A
A
T
T
A
C
T
A
A
T
T
C
T
A
A
G
A
G
T
A
A
A
A
G
T
T
G
T
A
C
A
G
A
A
A
A
T
G
A
A
A
A
G
T
T
18750
A
A
T
A
T
A
G
T
A
T
T
C
T
A
T
A
T
G
G
C
T
C
A
G
T
C
A
C
G
A
G
T
A
G
T
G
T
G
T
G
T
A
T
A
T
G
C
A
A
A
18800
A
G
T
A
T
A
C
A
C
T
G
T
G
T
A
A
A
T
A
T
A
T
A
T
A
T
A
A
A
C
A
T
A
T
C
T
A
A
A
T
G
T
A
T
A
T
A
T
G
T
18850
A
C
A
T
G
G
G
T
A
C
G
T
A
T
A
T
A
T
A
C
A
C
A
A
G
G
A
A
G
A
G
A
C
T
T
T
C
G
T
T
T
G
T
T
T
G
T
T
T
G
18900 |
REPEAT
T
T
T
T
G
A
G
A
T
G
G
A
A
T
C
T
C
A
G
G
C
T
G
T
T
G
C
C
C
A
A
G
C
T
G
G
A
G
T
G
C
G
G
T
G
G
C
G
C
A
18950
A
T
C
T
C
G
T
C
T
C
A
C
T
T
C
A
A
C
C
T
C
T
G
C
C
T
C
C
T
G
G
G
C
T
C
A
A
G
C
A
A
T
T
C
T
T
C
T
G
C
19000
C
T
C
A
G
C
C
T
C
C
C
A
A
G
T
A
G
C
T
G
G
G
A
T
T
A
C
A
G
G
C
A
T
G
C
A
C
C
A
C
C
A
T
G
C
C
C
G
G
C
19050
T
A
A
T
T
T
T
T
G
T
A
T
T
T
T
A
T
T
A
G
A
G
A
G
G
G
G
G
T
T
T
C
A
C
C
A
T
A
T
T
G
G
C
C
A
G
A
C
T
G
19100
G
T
C
T
C
T
A
A
T
T
C
C
T
A
A
T
C
T
C
A
G
T
G
A
T
C
C
G
C
C
C
C
C
A
T
C
A
G
C
C
T
C
C
C
A
A
G
T
A
G
19150
C
T
G
G
G
A
T
T
A
T
A
G
A
C
A
C
G
C
A
C
C
A
C
C
A
T
G
T
C
T
G
G
C
T
A
A
T
T
T
T
T
G
T
A
T
T
T
T
T
A
19200 |
REPEAT
G
T
A
G
A
G
A
C
A
G
G
G
T
T
T
C
A
C
C
A
T
G
T
T
A
C
C
C
A
G
G
C
T
C
A
A
A
C
T
C
C
T
G
G
G
C
T
C
A
A
19250
G
C
T
G
T
C
T
G
C
C
T
G
C
C
T
C
G
G
C
C
T
C
C
C
A
A
A
G
T
G
T
T
G
G
A
A
T
T
A
C
A
G
G
C
A
T
G
A
G
C
19300
C
A
C
T
G
T
G
C
C
T
G
G
C
C
C
A
G
G
A
C
T
C
T
A
A
C
T
T
T
T
A
A
G
T
A
T
G
A
A
C
T
T
G
T
A
A
G
T
T
A
19350
A
A
A
C
G
A
C
T
C
T
C
A
G
A
C
C
A
C
C
T
G
T
G
T
G
G
A
G
T
C
T
C
T
G
A
G
A
A
A
A
G
A
G
T
A
A
A
C
T
A
19400 |
REPEAT
T
T
T
T
A
A
T
A
G
T
C
C
A
G
G
G
A
G
A
A
G
T
G
A
T
C
A
A
G
T
C
C
T
T
A
T
C
T
A
G
G
A
C
A
G
T
G
G
C
A
19450
A
T
G
G
G
A
A
C
C
A
A
A
C
A
T
G
G
G
A
A
C
A
G
A
C
A
G
C
T
T
A
A
A
C
C
T
G
G
T
G
G
A
A
G
T
A
G
G
A
T
19500
C
C
A
C
T
G
A
A
T
T
T
G
A
T
G
A
C
T
A
A
C
T
G
G
A
T
G
T
A
G
A
A
A
A
T
G
A
A
G
A
A
G
A
A
A
T
G
T
T
G
19550
A
G
A
A
A
G
A
C
T
C
T
G
A
T
G
T
T
T
C
C
A
G
T
C
T
A
T
A
T
G
T
C
T
T
A
G
A
G
G
A
A
G
C
T
G
A
T
G
C
C
19600
C
C
A
G
G
C
A
G
C
T
T
C
A
T
A
A
A
A
T
G
G
A
A
C
A
A
G
A
A
T
A
G
A
T
G
T
T
G
A
A
T
C
A
G
A
G
A
G
A
A
19650 |
REPEAT
C
T
A
G
C
T
C
A
A
A
C
T
C
A
G
C
T
C
T
A
C
C
A
C
T
T
A
C
T
A
G
C
T
C
T
G
T
G
A
C
C
T
T
C
A
A
C
A
T
G
19700
T
T
A
C
C
T
A
A
C
A
T
C
T
C
T
G
A
G
C
C
T
C
A
G
C
T
T
C
T
T
C
A
T
C
C
A
T
T
A
T
A
T
G
A
G
G
T
T
A
A
19750
T
C
T
G
A
A
T
G
C
A
T
C
C
C
T
C
T
T
G
A
G
T
C
A
T
T
T
A
T
A
C
A
G
A
T
C
A
A
A
T
G
G
G
G
T
C
A
T
G
C
19800
A
C
C
T
A
G
T
G
T
G
C
T
T
A
G
C
A
C
A
G
A
G
T
G
T
G
G
C
A
C
A
T
A
G
T
A
A
G
A
G
C
T
C
A
A
A
G
G
T
T
19850
T
G
T
T
G
T
T
G
G
A
A
T
T
T
A
T
T
G
G
C
A
A
C
A
T
T
C
C
T
T
T
A
T
T
C
T
A
C
T
T
C
C
A
G
C
A
A
G
A
G
19900
C
C
T
C
C
A
G
T
G
G
T
T
T
T
G
T
G
T
T
G
T
T
G
T
T
G
T
T
T
T
T
T
T
C
T
T
T
C
T
T
T
T
T
T
G
A
G
G
C
A
19950 |
REPEAT
A
A
G
T
C
T
C
A
C
T
C
T
G
T
C
A
C
C
C
A
G
G
C
T
G
G
A
G
T
G
C
A
C
T
G
G
C
A
C
A
A
T
C
T
C
A
G
C
T
C
20000
G
T
C
G
C
A
A
C
C
T
C
T
A
C
C
T
T
T
T
G
A
G
T
T
C
A
A
G
T
G
A
T
T
C
T
C
A
C
G
C
C
T
C
A
G
C
C
T
C
C
20050
T
C
A
G
T
A
G
C
T
G
G
A
A
T
T
A
C
A
G
C
A
T
G
T
G
C
C
A
C
C
A
T
A
C
C
C
A
G
C
T
A
A
T
T
T
T
T
G
T
A
20100
T
T
T
T
A
A
G
T
A
A
A
G
A
A
G
A
G
G
T
T
T
C
A
C
C
A
T
G
T
T
G
G
C
C
A
A
G
C
T
A
G
T
C
T
C
A
A
A
C
T
20150
C
C
T
A
A
C
T
T
C
A
A
G
T
G
A
T
C
T
G
C
C
C
A
C
C
T
C
A
G
C
C
T
C
C
C
A
A
A
T
T
G
T
T
G
G
G
A
T
T
A
20200
C
A
G
G
C
G
T
G
A
G
C
C
A
C
C
G
C
A
T
C
C
A
G
C
G
A
A
A
A
G
A
G
A
C
T
T
T
T
T
T
A
A
A
G
G
A
A
A
A
G
20250
T
T
T
A
T
T
A
T
T
C
T
A
T
T
A
A
A
A
C
T
A
T
A
T
G
A
G
C
T
A
G
A
T
A
T
C
A
T
T
A
T
A
C
C
C
A
T
T
T
T
20300 |
REPEAT
A
T
A
G
A
T
T
C
A
A
C
T
G
A
A
G
C
T
C
T
G
A
C
T
T
G
T
C
C
A
A
G
G
T
C
A
C
A
C
A
G
T
G
G
G
C
A
T
T
C
20350
C
T
G
T
G
C
C
T
A
T
G
T
C
T
A
T
G
G
T
G
G
A
T
G
C
T
A
A
G
G
A
C
A
A
A
A
A
A
G
A
T
A
T
T
T
A
T
T
T
A
20400
A
T
C
A
A
T
A
A
C
A
G
A
T
T
T
T
T
T
C
A
G
T
G
T
A
G
A
C
A
A
T
A
G
C
T
A
G
G
A
C
T
T
C
T
G
T
A
G
T
A
20450
T
A
C
T
C
A
T
T
T
T
A
T
C
T
A
A
C
C
T
A
A
A
G
G
A
A
A
T
A
T
G
T
A
T
C
T
A
C
A
C
G
T
G
G
G
T
C
T
G
G
20500
G
T
A
T
T
A
G
G
G
T
A
A
A
A
T
G
G
G
A
T
G
A
C
T
G
A
A
T
A
G
C
T
G
A
G
T
A
T
T
T
C
T
C
T
T
A
C
C
T
C
20550
C
A
T
T
T
T
G
T
C
C
A
A
A
A
A
A
T
T
C
C
T
A
G
T
T
T
G
G
G
T
C
C
T
T
T
C
A
C
C
A
T
A
A
A
A
T
A
G
C
T
20600
T
T
A
T
T
T
A
A
A
A
A
T
A
C
A
C
A
C
C
T
T
A
C
A
A
T
A
G
A
A
G
G
G
A
C
C
A
T
G
C
T
T
G
C
T
T
T
G
T
A
20650 |
REPEAT
C
A
T
C
T
T
T
G
T
A
T
T
T
C
C
A
C
A
T
C
T
A
G
C
A
C
T
G
T
G
C
T
T
G
G
C
T
C
G
T
G
G
G
A
G
G
T
A
C
T
20700
C
A
A
T
G
C
C
T
A
T
G
T
A
C
A
C
A
A
A
A
G
A
A
T
T
A
A
T
T
T
A
T
A
A
A
T
G
T
C
C
A
T
A
A
A
G
T
G
C
T
20750
C
C
A
A
G
A
G
A
C
A
A
T
G
C
A
G
A
A
A
T
T
A
G
A
T
T
T
A
G
A
T
G
G
T
A
T
A
G
C
C
C
G
G
G
A
G
G
A
C
A
20800 |
REPEAT
T
G
A
C
T
G
A
G
G
C
A
A
C
T
G
G
G
T
G
T
A
A
G
T
G
T
C
T
T
G
A
C
A
G
C
A
A
A
T
A
T
C
A
G
G
T
G
A
A
G
20850
A
A
A
G
C
A
A
A
T
A
A
G
T
C
T
C
T
C
A
T
T
T
T
T
A
A
A
G
G
T
T
T
C
T
A
A
T
A
T
T
T
G
A
A
T
G
G
G
C
A
20900
T
C
A
C
T
C
T
A
A
A
A
G
A
A
A
T
T
A
A
T
T
T
A
T
T
A
T
T
A
C
C
A
G
G
G
G
T
A
A
T
G
G
A
G
C
T
A
G
C
A
20950
C
T
G
G
A
T
G
T
T
C
A
C
C
T
G
T
C
A
G
G
G
A
A
A
A
T
G
G
T
A
G
A
A
T
A
T
G
G
A
G
T
A
A
A
A
G
G
C
T
T
21000 |
REPEAT
G
G
A
C
T
T
G
A
G
T
T
A
C
A
G
C
T
G
A
G
C
T
G
G
A
G
C
C
T
T
G
A
A
T
C
T
G
C
C
A
C
T
T
C
A
T
A
A
T
T
21050
T
T
A
T
G
A
T
C
T
T
G
G
G
C
C
A
G
A
T
A
T
T
T
C
A
C
C
T
C
T
C
T
C
A
G
T
T
T
C
C
T
C
T
C
T
G
A
A
A
A
21100
A
A
A
A
T
A
T
A
A
T
A
A
T
A
G
T
A
T
C
T
A
C
C
T
C
A
T
G
G
G
G
T
G
C
T
A
C
G
C
T
G
T
C
T
A
A
T
T
C
A
21150
G
A
A
A
A
A
C
T
G
C
A
C
A
T
A
G
C
A
C
T
G
G
G
C
T
A
G
G
C
A
T
A
T
A
G
T
A
TTT GATCCATATT
21200
CACTACTATT ATTACTGTTT CTAGGAGAAA TTTACACCTT AATGGCAAAC
21250
TGGGACTTGA ATGGAATCTA AAATAGCTTC TAGTTTACCT GGGTTTACGG
21300
CATGTGGGGG ACGTATTGTC ATGTTGATGG CAGATAATAA CAATTCGGTT
21350
GAAATATCAC CTGTGTGATA TATAAGGTTT TGTCTTTTCT TTTTAAAG
T
T
21400 | Exon 4
V 122
G
C
T
C
C
A
G
A
A
C
A
G
C
C
T
C
A
A
A
A
T
T
T
A
T
C
C
T
G
C
A
T
A
C
A
G
A
A
G
G
G
A
G
A
A
C
A
G
G
G
21450
A P E Q P Q N L S C I Q K G E Q G 139
G
A
C
T
G
T
G
G
C
C
T
G
C
A
C
C
T
G
G
G
A
A
A
G
A
G
G
A
C
G
A
G
A
C
A
C
C
C
A
C
T
T
A
T
A
C
A
C
T
G
21500 |
var(21480):[A:0.03]
T V A C T W E R G R D T H L Y T 155
A
G
T
A
T
A
C
T
C
T
A
C
A
GTGAGTG AGAGGCTGTA TTTTTGCAGC TGTTTTGTAG
21550
E Y T L Q 160
ATCTTCTCTT AAATGACATT TAGAAATATC TGT
T
T
T
C
T
T
T
A
T
T
T
A
T
T
T
T
T
21600 |
REPEAT
A
T
T
T
T
A
T
T
T
T
A
T
T
T
A
T
T
T
A
T
T
T
A
T
T
T
A
T
T
T
A
T
T
T
A
T
T
T
A
C
T
T
A
T
T
T
A
T
T
T
21650 |
var(21632):[C:0.04]
A
T
T
T
A
T
T
T
A
T
T
T
T
G
A
G
A
C
G
G
A
A
T
C
T
C
A
C
T
C
T
G
T
C
A
C
C
A
G
G
C
T
A
G
A
G
T
G
C
A
21700
G
T
G
G
C
G
C
A
A
T
C
T
C
G
G
C
T
C
A
C
T
G
C
A
A
C
C
T
C
T
G
C
T
T
C
C
T
G
G
G
T
T
C
A
A
G
T
G
A
T
21750 |
var(21739):[A:0.02]
T
C
T
C
C
T
G
C
C
T
C
A
G
C
C
T
C
C
T
G
A
G
T
G
G
C
T
G
G
G
A
T
T
A
C
A
G
G
C
A
C
C
C
A
C
C
A
C
C
A
21800 |
var(21788):[A:0.07]
C
G
C
C
C
A
G
C
T
A
A
T
T
T
T
T
G
T
A
T
T
T
T
T
A
G
C
A
G
A
G
A
C
G
G
G
G
T
T
T
C
A
C
C
A
T
G
T
T
G
21850 |
var(21802):[C:0.06]
G
C
C
A
G
G
A
T
G
G
T
C
T
C
G
A
T
C
T
C
T
T
G
A
C
C
T
C
G
T
G
A
T
C
C
A
C
C
C
G
C
C
T
C
A
G
C
C
T
C
21900
C
C
A
A
A
G
T
G
C
T
G
G
G
A
T
T
A
C
A
G
G
T
G
T
G
A
G
C
C
A
C
A
G
T
G
C
C
C
G
G
C
C
TATCTGTT
21950 |
var(21932):[G:0.34]
TTATTTTTAC CAGAAAGGAG AAGCAATAGA TACTTCTAGA CAATTAGATA
22000
CTTTTTAAAG AGTTTCTATG TTTATAGTTA AAACTGGTTC ATTCATCTAC
22050
AGTATGAGAG ACCGAATGTC TTGGGTCTGA GTTCTAACTC AGAGTTCTCT
22100
TCAGTGCATC CAAGATCCAA GTTATAGCTG TTCTTTCCCA CTCTAG
T
AGG
22150 |
var(22147):[C:0.01]
GTTAAACTGG CTGCATAAGA T
C
GCTTCTCT TTTCTGCAGC
T
GTAGGCTCT
22200 |
var(22172):[G:0.18]
|
var(22191):[G:0.12]
TGGGGTCATG ATACATAAAT AAACTCTTCC TTGTGGTAGT TTCCCATTCG
22250
CTTGGATAAG TTTCTTTTTA AAGCACCATT GGCTGACCTA AGAGTCCATG
22300
AGAAGAGAGA GTCTGGGAGA TTCTGTTCCT TGAAGTAGAT TTCATGATCC
22350
CATTAAAGAT CCAGCTGATT TGTGCTATTC CTGAGTGAGG AGGAGATGGA
22400
GGAAAGGAGG GGTTCTGTAG TACATTTACT TTTTCTAACC TAAAGGAAAC
22450
ATCTATTGAC ACGCGGGTCT CAGTATTAGG GTAAAATAGC CCAGGATTCT
22500
ACTCTGGCCA CTGCTGTACT AGGAACTGAC AATTCTGTGC CACAGATGTC
22550
AAGGTGGCCA CAGTGCTTAG GATAATGTTT GGAACTGCCC TGGGGAGCCA
22600
AGATGACAAG CAGGGTTTGG GGAATTTCAG CAGCGTAGGC TTGGTTACCT
22650
ATCTACATGA ATGTGGAAGA ACATCTCAGT TCTACCAAAA AAGGGAGTTG
22700
GGTGAAGTAT AGTCTTACAT GACCATATAG TACAAATATT CCCGGGGTGT
22750
ATCCCCTAGT CATAAGATTG ACCTTTAAAA ATTGTCTAGA ATTCTAAATA
22800
TTTAAACATT TTGTTCTTTT CTACTGTAAG TAGAAAGTAG CACATAAAAC
22850
ATGTTGCTAC ACGTGGTTGT GTTTTGTTTA CAG
G
C
T
A
A
G
T
G
G
A
C
C
A
A
A
A
A
22900 | Exon 5
L S G P K 165
A
T
T
T
A
A
C
C
T
G
G
C
A
G
A
A
G
C
A
A
T
G
T
A
A
A
G
A
C
A
T
T
T
A
T
T
G
T
G
A
C
T
A
T
T
T
G
G
A
C
22950
N L T W Q K Q C K D I Y C D Y L D 182
T
T
T
G
G
A
A
T
C
A
A
C
C
T
C
A
C
C
C
C
T
G
A
A
T
C
A
C
C
T
G
A
A
T
C
C
A
A
T
T
T
C
A
C
A
G
C
C
A
A
23000
F G I N L T P E S P E S N F T A K 199
G
G
T
T
A
C
T
G
C
T
G
T
C
A
A
T
A
G
T
C
T
T
G
G
A
A
G
C
T
C
C
T
C
T
T
C
A
C
T
T
C
C
A
T
C
C
A
C
A
T
23050
V T A V N S L G S S S S L P S T 215
T
C
A
C
A
T
T
C
T
T
G
G
A
C
A
T
A
G
GT ACATTTTATT TCACTGTTTC ATTGGTACTT
23100
F T F L D I 221
TATAATTATT TTTAAAATCA CTCAAATCTT TTTTATATGG TTGTTTCAAG
23150
AAAGACAGAG ATTGATGGAA ATTGGCCAAC AGGCATAAGC AAAAGATAGA
23200
AGTTACTTTG ATGCAAGTAA AAGGGTGCAT TATTCTGAGC TATCTAAAGA
23250
TGGCTATACA AAGTGGGATG TTCAACATTA TTCTCTCTAT TGAAGAAATT
23300
AGCCCCTGGA TTCAAATCCC ATGAAAGAAC CAGCTACTAA TGATACCACC
23350
TGACTGAGGA GAGGGTCCTG TGAGGTCATT CAAGATGCTC AGTGCAAGCC
23400
CTTCTTGGAG GAGGTGTCCT TTC
A
CCCCCA TGGCTACTCC CATTGTTGTG
23450 |
var(23424):[G:0.11]
AGATAGGCTA CATGTGGGCC TGCTAGGCTA GAGCAGCGAG GTACAAACTA
23500
TAAATAAAAT TTCTCAAGTC ACAGATGCAT CTTGCTCTGA GAATACTCAC
23550
CTCCATCCCT GGAGTGAGCC AGTACATTTC TGAGCAAATG TAATCGGTCC
23600
AGTTGAATCA GAGGCCAATC TCAAGCATTC CAAGTTCTGA CCATCCAGGC
23650
AGAACTGGGC TGCCTGAAGT TCCAACCTCA CACTATGTGC TTCTCGCCTC
23700
TCTTTCCATG GCACTTCTCT GCATACATAT TGCTAACGAT GAGTCTGATC
23750
ATTGGCATTT ACTATACACT TTTCCACCAT ATTTCTTCTC AGGCTTCCTC
23800
CCATTTCTTT CATAGACC
G
T TCATCTCTAG GCTACCTTCT CGCCCCCTTG
23850 |
var(23819):[A:0.43]
TTCTTTTCCT CTGTCCCTTT GCTATGAATT TTCCTACGAA CATTTCTTCT
23900
CCTCCTGAGG CAGTCATC
A
C TAGCCGTCTC TGGCTTCTCA GTCATTGGAA
23950 |
var(23919):[C:0.16]
CTCTTGGGTT TGGCACATTG GTTTTTGAAA AACCACTGGA CTAAGTGTAG
24000
TTGAAACTTA CCACTAATGT TGGTAGTAGT TATTTGGTGA AAATGAGATT
24050
TGATTAAGGG GGATTATTTT AAAGATTCAG AAGTGAATCC AGCTTTTAAA
24100
AAAGTTCTTT CTTAAAGCCT GGAACTTTTC TCTTGTATAT TTTACCAAAT
24150
TTGATGGTTG TGCATCTCAG AACTGAGTTT TGTCAAACTC TTTATAGCTC
24200
ATGCCAGTAC ATAAGACAAT TGCTGATCAC AGATCCTGAA CCACACTTTT
24250
TTGTTTGTCC TGGTTACTAG
T
G
A
G
G
C
C
T
C
T
T
C
C
T
C
C
G
T
G
G
G
A
C
A
T
T
A
G
A
A
24300 | Exon 6
V R P L P P W D I R 231
T
C
A
A
A
T
T
T
C
A
A
A
A
G
G
C
T
T
C
C
G
T
G
A
G
C
A
G
A
T
G
T
A
C
C
C
T
T
T
A
T
T
G
G
A
G
A
G
A
T
24350 |
var(24320):[T:0.13]
I K F Q K A S V S R C T L Y W R D 248
G
A
G
G
G
A
C
T
G
G
T
A
C
T
G
C
T
T
A
A
T
C
G
A
C
T
C
A
G
A
T
A
T
C
G
G
C
C
C
A
G
T
A
A
C
A
G
C
A
G
24400
E G L V L L N R L R Y R P S N S R 265
G
C
T
C
T
G
G
A
A
T
A
T
G
GTAATTA TCTTTAGAGT GAAGGAAAAA ACACTGAAGC
24450
L W N M 269
A
TTCTTAATA TTGCTGCGCA GACCTCTGTC TTTTCATACA GCAAAAAATA
24500 |
var(24451):[T:0.08]
GAGTTTAAGA ATATTTATCC CAAAAGTACA CACGAGAGAA TTATCAGAAA
24550
GTCATGTATG CCTCTGTTGA TTAAGAAATA TCTTGAATTT TGATCTCTGA
24600
TTCTGAAATT TTTAAAGCTT TTGTAAACCA ATATTAATTT TCTATAGTTT
24650
ATTTCTAACA GAGGATTCAT TTCTCCTTAT TATTTACCCT GTCCTGTTAT
24700
TATTTTTTAG CATTTAAAAA AGATATTGAA AAGAGAAATA TTAAGAAATG
24750
TCCACAGAGA GTTATATAGA ATTTAATATT CCAAAGAAAA GGTCTACAAT
24800
TTAATATAAT ATTAGGCATT GCATGTTTTA AAATAAAAGG TATAGGATTA
24850
TGATTCTTTC CGGGATTGTT GTAAAATTCA ATGGCTTATA ATAACAAAGG
24900
ATCAGTCCCA CAGATAGCTG ATATTCAAGA GAGTATAACT AATTAAAGGG
24950
TTTTTTTTTT AAAAAAAAAA AGCCAGTGCT ATGTTTGTGT TAAAACATTC
25000
ATCACATCCT AATTGTAATC AAATAAAAAA TAATCTCTAG TGTAGAAACT
25050
TTGTAGTTTT CAATCTTATT TTTCAGCTGG TTTCAGGATT CCCCTCGAGA
25100
ACCTACATAG ATG
G
GTTCTT AGTACCCAGA GATTTTGTTT TATTTTTAAT
25150 |
var(25114):[A:0.01]
GAGATGCTAT CATTTCAGAT TAATATCATA TCTATTCGGT AAGACAGTCA
25200
CTGATATTTC TTCTCATTTA ATGGTAGGTC TGAAAAACAA ATAAGATCAA
25250
ATAGCCTGGG
T
TTTTTTTTT TTCATTTTAT GTTAAAATTC CTTAAATTAG
25300 |
var(25261):[G:0.12]
CAATCTAGTA TTAATAGGCA CTTTAAAAAA ATGTCTGTTT CAAG
G
T
T
A
A
T
25350 | Exon 7
V N 271
G
T
T
A
C
A
A
A
G
G
C
C
A
A
A
G
G
A
A
G
A
C
A
T
G
A
T
T
T
G
C
T
G
G
A
T
C
T
G
A
A
A
C
C
A
T
T
T
A
C
25400
V T K A K G R H D L L D L K P F T 288
A
G
A
A
T
A
T
G
A
A
T
T
T
C
A
G
A
T
T
T
C
C
T
C
T
A
A
G
C
T
A
C
A
T
C
T
T
T
A
T
A
A
G
G
G
A
A
G
T
T
25450
E Y E F Q I S S K L H L Y K G S 304
G
G
A
G
T
G
A
T
T
G
G
A
G
T
G
A
A
T
C
A
T
T
G
A
G
A
G
C
A
C
A
A
A
C
A
C
C
A
G
A
A
G
A
A
G
GTATA
25500
W S D W S E S L R A Q T P E E 319
TGTCCAAAAT ATACATACCT ATCGGGGAGC AATAAAGGGG AGAGAGGGGG
25550
GAAGATGTAA TGATTTCCTT GGAATAGAAT CTTTAAACTA CTGGTGCTGA
25600
ATCAAAAAGC ATGACTGCAT TAGTTAACAA GTTAATTTTT ATA
T
T
A
A
C
TT
25650 |
var(25644):[:0.11]
AAGTGCTGAA ACTGTTCAAG GAAATATGTT TGTGTTGCAA GGAAATTTTT
25700
AACATTGGGT AAGTTCTACT CCTGTTTGCT ATCAGTCATG TTGGTTATAA
25750
TGCTTGGTTA TAACTTATCT CTCTTACTAT CTCAGTAACT TATTTCACAG
25800
AGCTATAACC AGTAATTAAT CTCATTTCTT GTTAAAGCTT CATATGTTTT
25850
ATATTTTTGA TTCTATGAAA AGTAATGTGG CTCAATAAGC CATATGGAAA
25900
GCTTGAAAGA AAGTAGGCTC TGGAGACACA TATTTCAAAA TAAAATTTAG
25950
CATCCAGCAA TCCTCTCTTG TCCAAATATT ATAACACTGT ACTTCAAGCC
26000
TTTGATATTT ACTGCACAAA TGAGAACCAC CTGGCCACCC ATAACTATGA
26050
AAAGGATATC AAATGTGTTT TTCAGTCTGA TGAATTTTTC TTTTTTAGTA
26100
ATTATTGGGA AGGGAATGTT ATTGAAGTAT AAGAAAATAT TTTATTGAAG
26150
CAAAAATGCC TATGTAAACT TTATGCCAAT ATTAAATCTT TGGAGACACA
26200
AGAAATAGCC ATCTGAATAT TAGTTTTTAA AAGCACTCAT TTA
G
G
C
C
G
G
C
26250 |
REPEAT
A
T
G
G
T
C
G
C
T
C
A
G
G
C
C
T
G
T
A
A
T
C
C
C
A
G
C
A
C
A
T
T
G
G
G
A
G
G
C
T
G
A
G
G
T
G
G
G
C
A
26300 |
var(26276):[C:0.01]
G
A
T
C
A
C
G
A
G
G
T
C
A
G
G
A
G
T
T
C
G
A
G
A
C
C
A
G
C
C
T
G
G
C
C
A
G
C
A
T
G
G
T
G
A
A
A
T
C
C
26350 |
var(26306):[T:0.10]
C
A
T
C
T
C
T
A
C
C
A
A
A
A
A
G
A
C
A
A
G
A
A
A
T
T
A
G
C
C
A
A
G
C
A
T
C
G
T
G
G
T
G
C
G
T
G
C
C
T
26400 |
var(26388):[A:0.07]
G
T
A
A
T
C
C
C
A
G
C
C
A
T
T
C
G
G
G
A
G
G
C
T
A
A
G
G
C
A
G
G
A
G
A
A
T
C
A
C
T
T
G
A
A
C
C
C
A
G
26450
G
A
G
G
C
A
A
A
G
G
T
T
G
C
A
A
T
G
A
G
C
C
A
A
G
A
T
T
G
T
G
C
C
A
C
T
G
C
A
A
T
C
C
A
G
C
C
T
G
G
26500
G
C
A
A
C
A
G
A
T
C
G
A
G
A
C
T
G
C
A
T
C
T
C
A
T
A
A
A
T
A
A
A
T
A
A
A
T
A
A
A
T
A
A
A
T
A
A
A
T
G
26550 |
var(26516):[C:0.01]
|
var(26540):[G:0.03]
CACTCATTTA GTGATATAGT AGAGA
G
T
C
T
T
T
C
A
T
A
A
T
T
T
A
T
A
T
A
A
A
T
T
T
G
26600 |
NOT SCANNED
A
C
T
C
A
G
A
G
A
A
A
A
A
C
T
T
T
T
T
G
G
C
A
T
A
T
A
A
T
C
C
A
T
T
G
T
T
C
A
T
T
A
T
C
T
G
G
A
G
C
26650
T
T
T
T
G
T
A
A
C
A
T
T
A
A
C
G
T
G
C
A
A
A
A
T
C
T
A
A
A
T
T
C
T
T
A
T
T
T
G
T
G
A
A
A
T
T
T
A
T
G
26700
G
A
T
A
T
G
T
G
T
G
C
A
T
G
T
A
A
A
C
T
A
G
C
C
T
C
A
T
A
A
T
T
A
A
G
T
T
G
C
A
T
T
T
A
T
T
T
T
C
T
26750
G
T
G
A
G
C
T
A
C
T
A
A
T
G
G
C
T
T
T
T
G
A
T
A
A
C
T
G
A
T
G
A
T
C
C
T
T
A
G
C
A
A
T
C
A
T
A
C
A
T
26800
C
A
A
T
G
A
C
A
T
T
C
A
A
G
G
A
A
C
G
G
A
A
G
G
G
C
C
T
T
T
A
G
C
A
G
A
A
T
A
T
A
A
T
A
C
C
T
A
A
T
26850
A
T
A
T
G
A
T
T
C
A
T
A
G
A
A
T
A
A
T
C
T
T
A
T
A
T
T
C
T
T
C
C
T
T
A
C
T
T
C
T
T
G
T
A
T
T
A
A
T
T
26900
G
C
A
T
T
T
T
T
T
T
T
T
T
T
T
T
T
T
G
A
G
A
C
A
G
A
G
T
C
T
T
G
C
T
C
T
G
T
C
A
C
C
C
A
G
G
C
T
G
G
26950 |
REPEAT
A
G
T
G
C
A
G
T
G
G
C
A
C
A
A
T
C
T
C
A
G
C
T
C
A
G
T
G
C
A
A
C
C
T
C
T
G
C
C
T
C
C
T
G
T
G
T
T
C
C
27000
A
G
T
G
A
T
T
C
T
C
C
T
G
C
C
T
C
A
G
C
C
T
C
C
C
A
A
G
T
A
G
C
A
G
G
G
A
T
T
A
C
A
T
G
C
A
T
G
C
G
27050
C
C
A
C
C
A
T
G
C
C
C
G
G
C
T
A
A
T
T
T
T
T
G
T
T
A
T
T
T
T
C
A
G
T
A
G
A
G
A
C
A
G
G
T
T
T
C
A
C
C
27100
A
T
G
T
T
G
G
C
C
A
G
G
C
T
G
G
T
C
T
C
G
A
A
C
T
C
T
T
G
A
C
C
T
C
A
G
G
T
G
A
T
C
C
A
C
C
T
G
C
C
27150
T
C
G
G
C
C
T
C
C
C
A
A
A
G
T
G
C
T
G
G
G
A
T
T
A
C
A
G
A
A
T
A
T
A
T
T
T
T
A
A
A
A
A
T
T
G
T
C
T
A
27200
A
A
A
G
T
G
A
A
T
T
T
A
T
C
C
A
A
C
A
A
A
T
G
A
T
A
A
T
T
T
A
T
T
A
C
C
A
C
T
C
A
T
T
T
T
A
T
A
A
T
27250
A
A
A
A
T
C
T
C
T
T
A
A
T
G
T
T
G
A
A
C
C
A
C
T
T
G
C
C
C
T
C
T
G
G
T
T
G
T
T
A
C
T
T
T
T
A
T
A
A
T
27300
C
C
A
G
A
G
C
T
T
A
C
T
C
A
T
A
A
T
A
T
C
G
T
T
T
T
A
T
T
A
T
A
T
A
T
A
G
T
C
A
A
A
G
T
A
A
T
T
T
T
27350
T
T
T
A
A
A
G
A
C
T
A
T
C
T
C
A
T
G
A
A
T
T
A
G
A
T
T
T
T
G
T
T
T
A
T
A
T
A
T
G
T
G
G
T
A
C
A
G
A
T
27400
A
A
A
A
C
T
T
C
T
G
A
A
A
A
T
G
G
G
C
T
A
T
A
T
T
T
T
A
T
A
T
C
C
A
A
G
T
T
C
A
A
G
G
T
A
G
T
A
A
G
27450
T
A
G
T
C
T
G
A
A
A
A
A
T
A
T
T
T
A
A
G
T
T
A
T
A
T
C
A
C
A
T
T
A
A
G
C
T
A
A
A
C
T
A
T
A
A
A
C
T
A
27500
G
G
G
A
A
A
C
T
C
T
G
G
G
C
T
T
G
T
G
A
A
T
T
C
T
T
G
T
C
A
T
T
C
T
T
A
C
T
C
A
C
A
T
A
T
G
A
T
A
A
27550
T
G
A
C
C
T
A
G
T
T
A
G
A
G
A
T
G
T
G
T
G
A
A
A
A
G
G
T
T
T
T
T
C
T
T
T
T
C
T
T
T
T
T
T
A
A
A
A
A
G
27600
T
G
T
T
T
G
T
C
T
T
T
T
G
A
A
T
T
A
A
A
A
T
T
C
C
T
T
C
A
A
G
G
C
A
G
C
A
C
A
G
T
A
A
C
T
T
T
C
T
T
27650
A
T
T
T
C
C
T
A
T
A
A
A
A
T
A
A
A
C
C
A
C
C
A
T
C
A
T
A
A
C
A
A
T
G
A
G
T
A
T
A
G
C
A
A
C
T
C
A
T
T
27700
A
T
G
G
T
T
A
T
G
A
A
C
T
C
A
T
G
G
A
T
G
A
T
T
A
T
G
A
A
T
T
G
A
A
C
C
T
A
G
G
A
A
G
C
T
G
G
C
T
T
27750
A
T
T
C
A
G
T
C
A
C
T
G
A
A
G
G
T
A
T
T
C
A
T
A
A
A
G
A
G
A
G
A
A
A
C
C
C
A
T
A
C
T
C
T
G
A
G
A
T
A
27800
C
A
C
C
A
C
C
T
T
T
A
C
C
A
A
G
C
T
C
T
G
T
T
G
G
C
T
T
C
C
T
T
T
C
T
G
T
C
T
C
T
G
A
A
T
C
T
C
C
C
27850
T
T
T
T
C
T
A
T
G
T
T
T
G
A
T
T
T
T
T
C
T
G
T
G
G
G
T
T
G
T
T
G
T
A
G
G
T
C
T
T
T
T
T
T
C
T
C
T
T
A
27900
C
T
C
T
A
G
G
C
T
G
C
T
T
G
G
T
T
T
T
C
A
C
C
C
C
T
T
A
C
C
C
G
C
T
G
T
T
T
C
T
G
T
C
A
T
C
A
G
T
T
27950
T
C
T
T
T
A
T
G
A
A
A
C
A
C
C
A
A
C
T
G
A
T
G
T
A
A
A
C
G
T
A
A
A
A
G
G
T
G
T
G
A
A
T
T
T
T
T
T
T
T
28000
A
A
C
A
C
G
T
C
T
T
C
C
T
T
T
T
A
A
C
C
C
T
T
T
C
A
A
T
G
T
G
T
A
C
T
C
A
T
A
T
G
T
A
A
C
T
T
G
G
C
28050
A
T
T
T
A
A
A
A
A
A
A
A
T
T
A
A
T
A
G
T
A
A
G
C
T
T
T
T
T
T
T
T
T
T
T
T
T
T
T
T
T
T
A
G
G
T
A
C
T
C
28100
T
C
T
A
A
A
A
C
T
G
T
G
A
A
T
G
A
C
T
C
T
A
C
A
A
C
A
G
A
G
T
C
A
G
C
C
T
T
T
T
T
G
C
A
G
C
C
T
T
T
28150
G
C
T
T
C
T
C
A
A
A
A
T
T
G
A
G
A
G
A
A
A
T
G
T
A
A
C
A
T
C
T
C
C
G
G
G
T
G
G
A
T
T
G
G
T
G
T
A
G
T
28200
T
G
T
T
T
A
T
A
T
C
A
T
T
T
G
A
A
C
A
G
T
G
G
G
T
T
A
G
G
G
C
T
T
C
C
T
T
T
A
C
T
C
C
A
T
A
G
G
G
C
28250
C
C
T
T
T
A
C
T
A
T
G
T
C
A
T
T
A
A
A
T
T
C
A
G
C
T
C
C
T
A
T
C
A
C
T
G
A
A
A
A
A
C
A
C
T
T
T
T
T
A
28300
A
A
T
G
A
C
C
G
A
A
A
A
G
T
A
A
G
G
G
A
T
A
G
G
A
G
G
A
A
A
G
A
A
A
C
T
A
C
T
T
T
G
C
T
G
T
G
T
T
T
28350
A
A
G
A
G
A
A
C
A
G
T
C
T
T
G
A
A
A
T
C
A
G
C
A
T
C
C
A
T
C
A
A
A
G
G
C
A
G
G
C
C
T
G
A
T
A
G
T
G
A
28400
C
A
C
T
G
G
G
A
A
G
A
G
A
G
C
A
G
C
C
A
C
A
T
T
T
T
C
C
T
T
G
T
A
G
T
G
G
G
A
A
A
A
C
A
T
T
C
T
T
G
28450
A
A
T
T
T
G
A
G
C
T
C
A
A
G
G
T
G
T
C
C
A
G
A
C
A
T
G
C
C
T
G
A
G
A
A
C
A
T
G
C
A
C
A
G
G
T
A
T
T
G
28500
A
G
G
G
A
A
G
G
T
G
A
T
C
T
C
T
C
A
C
C
A
C
T
T
A
G
A
A
C
A
C
C
C
A
G
G
A
A
G
A
G
A
T
G
C
C
A
A
A
A
28550
T
A
C
T
G
A
T
T
A
A
T
C
A
G
C
T
A
T
T
C
C
T
T
A
G
A
G
C
T
A
T
G
T
T
A
C
C
A
A
T
A
T
G
T
C
T
C
T
G
T
28600
C
T
G
T
T
A
A
T
C
C
G
C
C
A
T
T
T
T
A
A
A
A
A
G
T
C
T
T
A
T
T
T
G
C
A
G
T
T
T
G
T
G
A
T
C
T
T
G
C
T
28650
C
A
A
C
T
C
T
A
T
T
A
C
A
G
C
T
A
A
C
A
A
A
G
G
A
A
T
C
G
T
T
G
C
A
T
G
T
T
C
A
T
T
C
G
T
A
C
T
T
T
28700
G
G
A
G
G
G
G
C
A
G
A
G
T
G
G
T
A
A
A
G
G
A
G
A
A
A
C
C
T
T
C
C
C
C
C
A
T
C
A
T
G
G
T
G
A
C
A
G
C
A
28750
A
G
G
G
T
G
A
G
G
G
G
T
G
A
A
T
A
A
T
C
C
C
T
A
A
A
G
G
G
G
G
A
G
A
A
A
A
T
G
A
A
G
A
G
T
T
A
C
C
A
28800
G
C
T
G
C
A
G
C
C
A
C
C
T
C
T
T
C
C
C
A
C
A
T
T
G
A
G
A
A
G
C
T
A
G
G
A
A
A
T
T
C
A
T
G
C
A
C
T
C
A
28850
T
T
T
G
T
A
A
T
T
T
A
A
A
A
A
T
A
T
T
G
C
C
A
A
G
A
T
A
A
G
A
T
A
G
G
T
G
T
G
A
A
C
A
A
T
T
A
A
A
T
28900
A
C
T
A
G
A
G
A
T
T
A
T
T
T
T
G
G
A
T
A
G
C
A
A
A
C
A
T
T
T
G
A
T
A
A
C
A
G
T
C
A
A
G
C
T
T
G
G
T
G
28950 |
REPEAT
G
A
T
T
G
G
C
A
A
A
C
A
T
T
T
T
C
T
C
T
A
C
A
G
G
T
C
C
A
G
A
T
A
G
T
A
A
T
A
T
T
T
T
C
A
G
C
T
T
T
29000
G
C
G
G
A
T
C
A
T
A
C
G
A
T
C
T
G
T
C
G
C
A
A
C
T
G
C
T
A
A
A
T
G
T
G
C
T
A
T
T
G
T
C
A
C
A
T
G
C
A
29050
A
G
C
T
G
C
C
A
T
T
G
A
C
A
A
T
A
C
C
T
A
A
A
C
A
A
A
C
A
G
G
C
A
T
G
G
C
T
G
T
G
T
T
C
C
A
A
C
A
A
29100
A
A
C
T
T
T
A
T
T
T
A
T
G
T
A
T
G
C
T
G
A
A
A
T
T
G
G
A
A
T
T
T
T
A
T
G
T
A
A
T
C
T
T
C
A
C
A
T
G
T
29150
C
A
C
T
A
A
A
A
A
G
G
A
T
T
C
T
T
C
T
T
T
T
G
T
T
T
G
T
T
T
T
G
A
G
A
C
G
G
A
G
T
C
T
G
G
C
T
C
T
G
29200 |
REPEAT
T
C
A
C
C
C
A
T
G
C
T
G
G
A
G
T
G
C
A
G
T
G
G
T
G
C
G
A
T
C
T
C
G
G
C
T
C
A
C
T
G
C
A
A
G
C
T
C
C
G
29250
C
C
T
C
C
C
G
G
G
T
T
C
A
C
G
C
C
A
T
T
C
T
C
C
T
A
C
C
T
C
A
G
C
C
T
C
C
C
G
A
G
T
A
G
C
T
G
G
G
A
29300
C
T
A
C
A
G
G
C
A
C
C
C
C
G
C
C
A
C
C
A
C
G
C
C
C
G
G
C
T
A
A
T
T
T
T
T
T
G
T
A
T
T
T
T
T
A
G
T
A
G
29350
A
G
A
C
A
G
G
G
T
T
T
C
A
C
C
G
T
G
T
T
A
G
C
C
A
G
G
A
T
G
G
T
C
T
C
G
A
T
C
T
C
C
T
G
A
C
C
T
T
G
29400
G
G
A
T
C
T
G
T
C
T
G
C
C
T
C
A
G
C
C
T
C
C
C
A
A
A
G
T
T
C
T
G
G
G
A
T
T
A
C
A
G
G
C
A
T
G
A
G
C
C
29450
A
C
C
G
C
G
C
C
C
G
G
C
C
G
G
A
T
T
C
T
T
C
T
T
T
T
G
A
T
T
T
C
T
T
T
T
C
A
A
C
C
A
T
T
A
T
C
A
A
A
29500 |
REPEAT
A
C
C
A
T
T
T
T
C
T
T
A
C
A
G
G
A
T
G
T
A
T
T
A
A
A
A
C
A
G
G
C
A
G
A
G
G
G
C
C
A
G
A
T
T
T
G
G
C
C
29550
C
A
T
G
G
G
C
C
G
T
A
G
T
T
T
G
C
T
G
A
C
C
C
C
T
A
A
G
C
T
A
G
C
T
A
T
A
C
T
C
G
A
A
A
G
C
A
T
C
A
29600
T
A
T
T
T
G
T
G
T
C
T
T
T
T
T
G
C
T
T
G
A
G
G
C
T
T
G
A
G
A
A
T
G
A
T
T
C
T
T
T
T
C
T
C
T
T
C
T
A
A
29650
A
G
A
G
A
T
T
T
A
T
A
T
C
A
G
A
C
A
C
T
T
T
C
A
C
T
A
A
C
A
G
G
A
A
A
G
T
G
T
T
A
T
G
T
T
T
A
A
G
A
29700
T
T
C
A
G
T
A
A
C
A
G
T
C
C
C
T
A
A
A
C
C
C
T
T
C
T
C
T
C
C
T
T
C
A
C
T
T
G
T
T
C
T
C
C
T
C
T
A
A
G
29750
C
T
C
A
G
C
A
C
C
T
A
T
C
T
T
G
G
A
A
G
G
A
A
G
G
A
A
T
G
A
T
A
A
T
T
C
A
G
A
A
C
T
C
T
T
T
T
C
A
A
29800
G
A
A
G
T
T
A
T
A
T
G
A
A
G
A
A
G
A
G
C
A
G
A
G
A
T
A
T
C
A
A
T
C
T
T
T
T
G
T
T
G
T
T
T
T
T
G
T
T
T
29850 |
REPEAT
T
T
A
G
G
A
T
C
T
G
A
G
A
T
A
A
T
A
C
A
G
T
G
T
A
T
C
T
G
C
A
A
G
G
G
G
A
T
G
A
A
A
A
G
A
G
T
C
C
A
29900
G
C
A
G
A
G
A
A
G
G
A
G
A
A
A
T
T
A
A
T
G
A
C
A
C
A
G
G
G
A
A
G
G
T
G
G
G
G
A
T
A
A
T
G
A
C
T
G
G
A
29950
G
A
G
A
T
G
T
C
T
T
T
G
A
T
A
A
A
G
C
A
A
G
A
G
G
G
A
G
C
G
G
G
G
T
C
C
A
G
A
A
C
T
C
T
A
G
C
T
A
A
30000
A
G
A
G
T
T
G
G
A
C
C
G
T
G
A
T
G
G
A
A
G
T
A
G
G
G
A
T
G
A
T
T
C
A
T
C
C
A
C
T
G
G
G
A
C
A
T
C
A
T
30050
T
A
A
C
A
G
T
G
C
T
G
T
G
T
T
A
G
G
G
A
A
T
T
G
G
T
T
G
G
G
G
G
A
G
T
T
T
G
A
A
C
G
T
T
T
T
C
A
T
G
30100
G
T
G
G
A
A
A
A
A
G
A
A
G
G
G
A
A
T
T
T
C
C
A
T
C
T
G
A
T
T
T
C
T
T
C
C
T
T
T
T
G
C
T
C
G
G
T
G
A
A
30150
G
T
C
T
G
A
G
G
C
A
A
G
G
T
C
A
T
C
T
C
T
T
T
T
T
C
A
T
A
T
T
G
G
T
G
G
C
T
T
C
T
T
C
C
A
C
T
T
T
A
30200
A
C
C
C
T
A
C
A
G
T
T
T
T
T
T
C
C
T
T
T
A
C
A
G
A
C
A
A
A
G
T
A
T
T
T
T
C
A
T
C
T
G
A
C
T
T
C
C
A
T
30250
T
T
C
T
C
A
T
A
T
T
T
G
T
A
T
G
C
T
T
A
G
T
C
A
T
T
T
G
T
A
C
C
C
A
T
T
T
C
T
T
T
T
G
A
A
A
T
C
A
C
30300
T
T
G
A
A
C
A
T
A
C
T
G
G
C
C
T
T
T
G
G
C
T
T
T
T
T
T
T
T
T
C
T
C
A
T
G
T
G
C
C
T
A
T
A
A
T
A
G
T
T
30350
T
T
A
T
C
T
G
T
A
T
T
T
G
G
C
T
A
G
A
T
A
A
C
A
T
T
G
A
G
G
T
T
A
G
A
A
C
T
T
T
T
A
G
T
G
A
C
T
C
T
30400
G
T
G
A
C
A
G
T
T
G
A
A
T
G
T
C
A
A
A
G
A
T
T
C
T
C
C
T
C
C
C
T
A
T
T
A
G
C
C
C
T
T
G
T
G
T
T
G
C
T
30450
T
T
A
A
G
C
A
G
C
A
G
T
G
A
T
T
T
T
A
C
A
C
C
C
C
T
G
G
T
C
A
T
G
A
A
A
T
G
T
T
A
C
A
C
T
T
T
T
T
A
30500
G
A
G
A
C
T
C
A
T
G
C
A
G
A
T
T
C
A
A
C
T
A
A
T
G
A
T
T
T
C
T
C
T
C
C
C
A
T
G
A
A
G
G
T
A
T
A
C
A
T
30550
T
G
C
A
G
G
T
A
G
G
C
A
C
C
A
T
T
A
A
C
A
T
T
T
C
A
G
T
T
T
A
C
T
T
G
C
A
A
T
T
T
A
C
C
T
T
G
T
G
A
30600
A
A
A
G
A
A
T
A
T
A
A
T
T
C
T
A
G
A
A
T
T
T
G
A
T
T
C
T
T
A
G
C
T
C
T
G
T