Hugo        AllelePos a.a.Pos Residue   Variant   ADfreq    EDfreq    PPHpredict              SIFTpredict   
do          004175    108     G         V         0.10      0.00      benign                  TOLERATED     
do          004202    117     T         I         0.08      0.00      benign                  TOLERATED     
do          004257    135     D         E         0.02      0.00      benign                  TOLERATED     
do          004418    189     T         M         0.00      0.02      benign                  TOLERATED     
do          004645    265     D         N         0.25      0.32      benign                  TOLERATED     
do          015732    300     L         V         0.09      0.17      benign                  INTOLERANT