CYP26B1 Color FASTA
The longest form of insertion/deletion sites is shown in the FASTA sequence and contain a '-' as the alternate allele in the variation tag.
*Display courtesy of
GeneSNPs
T
C
T
C
A
C
C
A
C
G
C
C
T
C
C
G
G
C
T
T
T
G
T
G
A
G
C
G
C
G
C
G
G
G
T
T
G
G
G
G
C
G
G
G
G
G
G
G
T
G
50 |
NOT SCANNED
C
T
G
G
C
G
G
G
G
C
G
C
C
C
A
C
G
G
C
G
C
A
G
C
C
T
C
C
C
G
C
C
T
C
T
A
T
A
T
A
A
A
C
A
C
A
C
G
C
A
100
T
C
G
C
C
T
C
G
C
T
T
T
G
G
A
C
T
C
A
A
A
T
T
C
A
C
A
T
T
G
A
G
A
G
A
A
G
C
T
T
T
T
A
A
A
A
C
C
A
C
150
C
A
G
C
C
C
T
G
A
A
A
T
C
C
T
G
C
C
T
C
C
T
G
C
T
T
T
T
C
C
C
C
C
T
C
T
T
T
C
A
T
T
C
C
T
T
T
T
G
C
200
C
T
T
C
C
T
T
T
C
T
T
T
T
T
T
C
C
C
C
A
T
T
T
C
T
T
C
C
C
C
C
A
G
C
A
G
C
A
A
C
T
C
C
A
G
A
G
C
C
G
250
A
G
A
G
A
C
C
G
C
G
T
C
C
C
G
G
G
A
C
G
G
A
C
T
G
C
C
T
T
T
T
C
T
T
A
A
T
T
G
A
T
A
C
A
A
T
A
G
C
C
300
C
A
G
C
T
C
G
G
G
T
T
T
T
C
C
A
C
C
T
C
C
T
C
C
C
C
C
A
A
C
C
C
C
A
C
C
C
C
G
C
C
T
C
A
C
C
C
C
T
C
350
C
C
G
C
C
C
G
C
T
G
C
C
G
C
C
G
C
C
G
C
C
G
C
C
G
C
C
G
C
C
G
C
C
G
C
C
G
C
C
G
C
C
G
C
C
C
C
A
T
C
400
G
C
C
C
G
C
C
C
G
G
G
G
C
T
C
T
G
T
C
G
C
C
G
G
C
T
G
C
G
T
C
C
C
G
T
C
C
C
G
G
C
C
G
C
G
G
C
C
C
G
450
C
C
G
G
C
T
C
C
G
C
A
C
C
C
G
C
G
C
T
C
G
G
G
C
C
G
C
A
G
C
G
C
C
C
G
C
C
T
C
G
C
C
G
C
C
T
C
G
C
C
500
C
G
C
C
G
C
T
C
C
T
G
C
C
T
C
G
G
G
G
G
T
G
C
T
G
C
G
G
C
G
G
C
T
C
T
G
G
G
G
C
T
C
G
A
G
C
G
C
G
C
550
C
G
C
C
C
C
G
G
G
C
A
G
C
C
C
A
G
G
G
A
C
T
T
T
T
A
G
G
C
T
C
C
G
G
C
C
T
C
T
C
C
A
C
T
C
G
C
C
T
C
600
A
G
C
C
A
G
G
G
A
G
C
T
T
T
C
T
C
C
C
T
C
G
C
C
C
C
C
A
A
A
G
T
T
T
C
T
G
G
G
T
T
C
G
T
T
G
G
A
A
T
650
T
T
T
T
G
G
A
T
T
C
A
G
G
A
A
T
T
T
T
T
T
C
T
T
T
T
T
T
T
C
T
T
T
T
T
T
T
C
A
C
C
T
A
G
G
A
A
TTT
700
TGGGGCCATA CTGCAATACT TTTGACAAAT CGACCGCACT TTCTCTCTGC
750
TAGCTCTCTG CCCCCTTCTT TTTTTCCGAG CAGGGGAAGG GGCTTACGAG
800
AGAGAGGCTC CCTCTGGACA AAGTTTTCCA AAGTTTTCCG AGTGTGATGG
850
TAGCGGGGAG AGCAAACCCA CCAGCTTGAC TCACGGCTTC ATCTCACCAC
900
CCCTTGAGCA GCCCCTAAGC CCGCTATAAA GGAACAAACA AACAAACAAA
950
CAAA
C
A
A
A
G
T TGCACCCCAG TCGCCTCGTG TTTCCTCTCT TCTTTTAGGC
1000 |
var(955):[:0.01]
AATTTTTTTC CTCCCTCTCT CCGCTCCCCT CGCAGCCTCC ACTCCCTTTC
1050
CCTTGGCCCC TTCCTCCTTC TCTGTTTCGG CTGGAGGTGC CAGGACCCCC
1100
GGCCGCAGCC TCCCCTCCCC CGCCGCTCCG GTCCCCTCCC GTCGGGCCCT
1150
CCCCTCCCCC GCCGCGGCCG GCACAGCCAA TCCCCCGAGC GGCCGCCAAC
1200
A
T
G
C
T
C
T
T
T
G
A
G
G
G
C
T
T
G
G
A
T
C
T
G
G
T
G
T
C
G
G
C
G
C
T
G
G
C
C
A
C
C
C
T
C
G
C
C
G
C
1250 | Exon 1
M L F E G L D L V S A L A T L A A 17
G
T
G
C
C
T
G
G
T
G
T
C
C
G
T
G
A
C
G
C
T
G
C
T
G
C
T
G
G
C
C
G
T
G
T
C
G
C
A
G
C
A
G
C
T
G
T
G
G
C
1300
C L V S V T L L L A V S Q Q L W 33
A
G
C
T
G
C
G
C
T
G
G
G
C
C
G
C
C
A
C
T
C
G
C
G
A
C
A
A
G
A
G
C
T
G
C
A
A
G
C
T
G
C
C
C
A
T
C
C
C
C
1350
Q L R W A A T R D K S C K L P I P 50
A
A
G
G
G
A
T
C
C
A
T
G
G
G
C
T
T
C
C
C
G
C
T
C
A
T
C
G
G
A
G
A
G
A
C
C
G
G
C
C
A
C
T
G
G
C
T
G
C
T
1400
K G S M G F P L I G E T G H W L L 67
G
C
A
G
GTAAGG GCGCGCTCGC TCCGCTGCAC TCCGGGGTCC GCTAGCTGCG
1450
Q 68
AGCGCGGGGC AGACGGAGCG GCGGGCCGGC CAGGGGGCGC CGGGAGCCTG
1500
AAGGCACTGG TCCCCGCCCC GCCCCTTCCC TCCTCTCTGC CGCAGCAGCC
1550
CGGGCTTCCC CAGCCCGCCG GCAGCGCGGT TCCGGGACCA CTGGCGCCCG
1600
CGGCGCAGGT TCAGGGGGCT GGTAAGAGGG GTTCCCGGAC CTGAGGGGGC
1650
TCCCAAGATG GACTTGCCTG GGTCGCGGCT GGCCTGGCAG GGGGCGTGGA
1700
GCGCCCCGGG GGCGCCTAGC GAGGCGCG
A
T CCCGGGGGAG GGTCCGGTCC
1750 |
var(1729):[G:0.02]
TGAGCCGCTT TCGCCTCCCC T
C
GGTGCTGC AAGCCCCCAG TCGCCCTCGG
1800 |
var(1772):[G:0.01]
CTTTCTGGGG TTGGCTGTGT CGCTGGGAGC CGAAAATTGA GTCGGGAGAG
1850
GAGGGGGCTG GTGGCAGCTT GAATTGCCGA TTTAAAACTG TGTTCCTGCG
1900
GCGCCGTCGG CAGCGCCAGG TACAGTGTCC CTGGTCCGCG GTCCGCGCGA
1950
GTGTGTCTGT TTTGTGGTGG AAGA
G
G
A
A
G
A
A
G
G
T
A
A
C
C
C
A
A
G
G
A
A
A
A
A
T
G
2000 |
NOT SCANNED
A
G
A
A
T
C
C
A
G
G
G
C
T
C
T
A
G
G
C
T
T
T
C
G
G
G
G
A
A
A
A
G
G
G
T
C
T
A
T
T
T
A
C
T
T
A
T
T
G
G
2050
G
T
G
G
G
G
A
C
A
G
T
T
T
G
G
C
A
G
G
A
G
A
G
G
G
A
A
A
C
T
T
G
G
G
A
G
A
G
G
T
G
A
G
T
G
T
G
G
G
A
2100
T
C
C
A
T
A
G
A
G
A
G
A
G
A
G
T
G
C
G
T
G
T
G
T
G
C
T
T
G
T
T
A
G
A
T
G
C
C
G
C
A
C
A
A
C
C
C
C
A
C
2150
T
C
T
G
C
T
G
G
T
G
A
T
A
A
C
G
G
G
G
G
T
G
A
G
G
C
G
C
G
T
C
A
G
G
G
A
C
C
A
G
A
C
C
C
A
G
G
T
A
G
2200
G
T
A
A
T
G
G
G
G
A
G
A
T
T
A
A
C
C
T
G
G
A
G
T
T
C
A
C
C
T
C
A
T
C
A
A
G
T
G
C
C
A
G
A
C
A
A
T
C
G
2250
C
T
T
T
T
G
C
A
A
T
G
T
G
A
T
A
C
A
C
A
C
C
G
G
T
T
T
T
C
T
T
C
T
T
G
G
G
G
T
G
G
G
G
G
A
G
C
G
G
A
2300
G
C
G
C
C
T
C
T
G
C
A
G
T
A
A
C
T
G
C
G
G
G
A
G
G
T
G
T
A
T
T
T
G
T
G
T
G
T
A
C
G
C
G
C
G
T
T
T
G
T
2350
T
C
T
G
T
T
A
G
G
G
G
A
A
G
C
A
G
G
G
A
T
G
T
C
C
T
G
A
A
A
C
T
G
A
C
A
A
T
C
C
C
C
G
C
A
C
T
A
G
A
2400
G
A
G
G
T
G
A
A
G
C
G
A
A
A
G
G
T
G
A
G
C
G
C
T
G
C
G
A
C
C
T
G
T
G
G
G
T
T
T
A
C
A
G
G
T
G
C
G
A
A
2450
A
G
C
T
T
G
G
C
T
T
G
A
A
A
T
T
A
A
C
A
G
A
C
G
C
G
T
G
C
A
A
T
C
C
G
C
G
C
G
C
T
C
G
C
G
C
A
C
A
C
2500
A
C
G
C
A
C
T
C
A
C
C
C
T
G
C
C
C
C
G
G
G
A
C
G
A
G
T
G
A
C
A
G
C
G
G
A
G
C
G
G
G
G
G
C
G
G
G
G
A
G
2550
G
G
G
G
T
T
C
G
A
A
G
T
T
C
C
T
C
T
G
C
C
C
T
G
T
G
G
T
C
T
T
T
C
C
A
C
G
T
C
C
C
G
G
A
T
T
A
G
G
C
2600
C
C
A
T
C
T
C
T
T
T
T
T
G
G
G
G
T
T
G
T
T
C
G
T
G
C
A
A
T
G
A
G
G
T
G
G
G
G
G
T
C
C
T
T
T
C
A
A
C
C
2650
A
A
T
G
G
A
T
G
T
A
T
C
A
C
C
C
C
C
C
C
A
C
C
C
C
C
C
G
C
A
A
A
G
A
A
A
T
C
C
C
C
A
G
A
G
C
C
T
T
T
2700
C
C
C
T
C
G
C
C
A
C
C
A
C
A
C
T
T
A
A
A
G
T
G
T
C
A
A
C
T
G
C
A
G
C
G
G
T
G
C
T
C
T
A
G
G
C
T
T
T
G
2750
G
G
C
C
G
C
G
A
A
T
T
T
A
G
G
A
A
A
T
A
A
A
A
T
A
A
C
T
T
G
G
G
C
A
A
C
G
G
C
T
C
C
C
G
C
C
T
T
T
T
2800
A
G
A
G
C
C
A
G
T
C
T
G
C
T
G
A
A
T
C
C
A
C
G
G
T
C
T
G
T
C
A
C
C
A
C
C
C
A
C
C
C
C
C
A
C
T
T
C
G
T
2850
T
T
C
C
T
G
A
C
C
T
C
T
C
T
G
C
C
C
C
C
C
C
T
C
A
G
G
T
C
C
C
C
A
T
G
A
C
C
T
T
T
T
C
T
C
C
G
A
A
T
2900
C
C
C
A
C
A
A
G
A
G
C
C
C
C
T
G
G
G
G
G
T
C
A
G
C
G
T
C
C
A
A
C
C
T
G
C
A
C
A
G
A
A
G
T
T
A
G
G
G
A
2950
G
G
A
G
G
A
A
A
C
C
T
A
A
G
C
C
T
C
C
C
C
A
T
C
C
C
T
C
C
A
A
C
C
C
G
G
G
G
C
C
C
T
A
G
A
T
C
T
G
G
3000
A
G
G
T
G
A
G
G
A
G
G
G
A
A
A
T
A
G
G
G
G
G
T
A
C
G
T
G
T
A
C
A
G
G
A
G
C
G
C
C
T
A
A
G
G
G
G
T
T
A
3050
A
T
G
A
G
A
G
C
C
C
T
C
T
G
A
A
T
C
C
C
A
G
C
G
T
T
A
T
T
T
T
T
T
C
G
G
A
G
T
C
A
T
T
T
A
T
C
A
G
A
3100
T
T
T
T
A
C
G
G
G
G
G
G
A
C
C
T
C
C
A
A
G
G
G
C
T
C
T
C
C
G
T
T
T
C
C
A
C
C
G
A
G
C
G
C
C
A
T
C
T
A
3150
A
A
C
A
G
A
G
C
C
C
A
G
G
G
C
T
A
A
A
A
A
T
A
C
A
A
C
A
T
T
T
T
T
G
T
A
T
A
A
A
T
T
G
G
A
C
T
C
G
C
3200
G
G
C
C
C
G
A
G
C
G
G
C
C
G
C
C
C
C
T
A
T
G
A
A
A
G
T
A
C
T
C
T
T
T
G
T
G
A
A
G
A
C
C
G
T
G
G
A
A
A
3250
C
G
G
C
G
G
A
C
A
A
A
T
A
A
C
T
C
T
T
T
A
T
T
A
A
T
G
C
C
A
C
A
A
A
A
A
A
C
G
C
A
C
T
T
T
A
A
T
T
A
3300
T
A
G
T
T
A
G
G
C
A
G
A
T
C
A
G
A
G
G
C
G
G
G
G
G
G
T
G
G
G
G
G
C
G
A
G
G
C
G
G
C
G
G
C
G
A
C
C
T
C
3350
G
G
A
A
A
A
T
T
C
A
C
A
A
C
C
C
A
A
C
T
T
T
T
G
T
G
T
T
G
A
A
A
G
A
A
A
A
G
A
A
A
A
A
C
A
G
A
G
G
A
3400
A
A
A
G
A
A
G
G
A
G
A
G
G
A
A
A
G
A
C
G
G
A
G
A
G
T
G
A
G
A
C
G
G
A
G
C
G
A
G
G
G
A
G
A
C
G
G
G
T
A
3450
T
A
G
C
A
G
A
C
G
G
A
G
G
G
A
G
G
G
A
A
A
C
C
C
T
C
G
C
C
T
C
A
C
C
A
C
C
C
C
T
T
C
T
G
T
C
G
C
A
C
3500
C
C
C
A
C
C
T
C
C
G
C
C
T
A
G
A
T
T
T
T
T
C
T
T
A
A
A
G
G
G
G
T
A
G
A
C
G
C
C
G
T
C
T
A
G
A
A
G
G
G
3550
C
T
G
C
A
C
G
G
C
A
G
G
G
G
G
A
A
T
T
A
T
C
C
C
C
G
C
C
T
T
C
C
A
G
C
C
T
G
G
G
A
G
G
G
G
G
A
C
A
G
3600
C
G
T
T
C
C
C
G
C
G
G
C
C
C
A
G
C
C
C
C
C
C
T
C
C
T
G
G
C
T
G
C
G
C
G
G
G
C
G
C
T
C
C
C
A
G
C
T
C
G
3650
T
T
C
C
C
C
G
T
C
G
C
G
C
G
C
C
G
G
G
C
C
G
G
A
G
G
C
G
C
A
T
G
T
G
G
A
A
A
A
G
T
G
A
T
T
A
G
G
G
C
3700
T
C
C
G
G
G
T
T
C
T
G
C
A
G
A
G
T
C
A
C
T
T
T
T
C
G
G
C
T
G
T
A
C
T
G
G
C
G
T
G
T
G
T
G
C
A
C
A
T
T
3750
T
A
G
C
T
G
G
A
A
G
T
A
G
T
T
T
T
C
T
G
T
G
G
A
A
A
A
A
A
G
G
A
A
A
G
T
G
A
G
G
A
G
G
G
G
G
A
C
C
A
3800
A
C
C
C
G
G
G
C
T
A
G
G
G
G
G
A
C
T
G
A
G
T
T
G
T
C
C
C
C
T
C
G
G
G
G
G
T
G
C
A
G
G
A
G
C
G
G
G
T
A
3850
G
A
T
C
T
G
G
A
G
C
C
C
G
A
G
T
C
G
G
T
A
C
G
C
T
C
G
T
G
G
G
C
T
G
G
C
A
G
G
C
G
G
G
G
C
G
G
C
T
A
3900
G
A
C
A
G
G
T
G
G
C
G
C
C
C
C
T
C
C
C
C
T
T
T
G
C
G
C
C
G
G
G
T
G
C
T
G
C
C
C
C
G
G
C
A
G
G
A
G
A
A
3950
G
G
G
T
T
A
A
C
G
T
G
G
G
G
T
G
G
G
G
T
A
A
C
T
A
G
T
G
C
C
G
A
C
G
T
C
A
A
A
G
G
T
G
A
G
C
G
G
G
A
4000
C
G
C
C
C
T
T
G
C
C
C
C
C
G
C
C
C
C
T
C
T
G
A
G
G
T
C
T
C
C
A
C
G
G
T
T
T
C
C
G
G
T
A
C
C
C
G
C
G
C
4050
C
C
G
G
C
C
G
G
C
T
C
C
G
C
C
A
G
C
C
G
T
T
T
C
G
A
G
A
G
T
C
C
G
G
C
C
G
G
C
C
C
C
G
G
C
C
C
C
G
C
4100
C
A
T
C
C
T
C
G
G
C
T
T
G
C
G
C
C
G
C
C
A
C
C
A
C
C
G
G
G
G
A
T
C
T
G
G
T
T
A
C
C
T
G
C
G
C
G
G
G
T
4150
C
G
C
C
C
T
G
C
C
C
G
G
T
C
C
C
G
C
C
C
C
G
C
C
C
C
G
C
G
C
T
C
G
G
G
T
T
C
C
A
A
A
C
T
C
C
A
G
G
G
4200
C
G
G
CAACCAA AGTCCGTCTC CGTTATTTCC AGGGCAAAAT GCATTAGGAA
4250
AATCGCGGCT CTGGGCCCGT GACCCCGCCC TGCAGAGTCC TCCGAGGGCC
4300
GCCGGGTCCC TGCGCGGGCC ACACCGGAGA GCGGAGGAAA CTCCAACCCC
4350
CATCTGTAGT TGCTGCCTCC GGGCACCGAC CGCTTACCGC TATAAATAAT
4400
CTTTGGCCTG CGGCCACCCC GCGGGGTCTC GCCAGCCCGT GGCCCGGAGC
4450
CTGGAAATAT TTATTCCGAG AGGCTCCCGA GCGCGGGGTG G
G
GGTGTGGG
4500 |
var(4492):[C:0.01]
GGTGGGGGTG GGGGCGGAGA CTCCCGCTTC GGGTCCAGCT GTCCGGGATA
4550
CCTCTTTCCT CTCGAAAGTC ATTACCAA
A
A AACAGCCT
C
C TGGGGGTGCC
4600 |
var(4579):[G:0.01]
|
var(4589):[T:0.01]
CCTGGGCCTC CGCCTCCTTG CATTATTTAT TATCCTCTAG GCCCTACTTC
4650
GCAGTTCTTG TGCACGCTAT GAAAAATAAA ACCTGCGTGC TCGTCTGTGT
4700
GAGTGTGTTT GGTGGGGAGA GGGGGCAGGT GACTGTACCC CGGGTTGGGG
4750
TCCGCCGCCC CTCCCTCGCG GGCCCTCTGC AGAAGTGCAC CCTGAGAGAG
4800
ACCCGGGTGT GGCTCCCGCA G
G
G
T
T
C
T
G
G
C
T
T
C
C
A
G
T
C
G
T
C
G
C
G
G
A
G
G
G
A
4850 | Exon 2
G S G F Q S S R R E 78
G
A
A
G
T
A
T
G
G
C
A
A
C
G
T
G
T
T
C
A
A
G
A
C
G
C
A
T
T
T
G
T
T
G
G
G
G
C
G
G
C
C
G
C
T
G
A
T
A
C
4900
K Y G N V F K T H L L G R P L I 94
G
C
G
T
G
A
C
C
G
G
C
G
C
G
G
A
G
A
A
C
G
T
G
C
G
C
A
A
G
A
T
C
C
T
C
A
T
G
G
G
C
G
A
G
C
A
C
C
A
C
4950
R V T G A E N V R K I L M G E H H 111
C
T
C
G
T
G
A
G
C
A
C
C
G
A
G
T
G
G
C
C
T
C
G
C
A
G
C
A
C
C
C
G
C
A
T
G
T
T
G
C
T
G
G
G
C
C
C
C
A
A
5000
L V S T E W P R S T R M L L G P N 128
C
A
C
G
G
T
G
T
C
C
A
A
T
T
C
C
A
T
T
G
G
C
G
A
C
A
T
C
C
A
C
C
G
C
A
A
C
A
A
G
C
G
C
A
A
G
GTA
A
5050 |
REPEAT
T V S N S I G D I H R N K R K 143
G
A
A
C
T
C
T
G
C
C
C
G
T
T
T
T
C
T
T
C
C
G
C
G
C
A
A
T
C
C
C
T
C
C
C
C
C
A
C
C
T
C
G
G
G
G
C
A
A
G
5100
G
A
G
T
T
C
C
T
G
G
A
G
C
C
C
G
G
G
G
A
A
T
G
T
C
C
C
C
T
A
C
C
G
A
A
T
C
T
G
T
G
C
C
C
C
C
C
T
T
T
5150
G
C
A
C
A
C
C
A
T
G
C
T
T
G
A
A
G
A
C
T
C
C
G
C
A
G
T
T
C
C
C
C
G
C
C
G
A
C
A
A
G
G
C
C
T
C
G
A
G
T
5200
C
C
G
G
A
T
C
C
A
G
G
G
C
C
T
G
C
T
C
C
G
G
C
C
T
C
C
T
C
T
T
G
G
T
C
C
C
T
T
T
T
C
T
T
G
C
T
G
G
C
5250
C
G
A
C
T
G
C
G
T
C
A
T
G
G
G
C
A
C
C
C
C
C
A
A
C
G
G
T
G
G
C
T
T
G
G
A
A
G
A
G
C
T
T
G
A
G
C
G
T
G
5300
C
G
G
G
G
T
C
T
G
G
G
G
T
G
T
C
C
A
A
A
G
C
C
T
G
T
C
C
T
T
G
C
C
T
T
G
C
T
C
C
A
C
A
G
A
G
C
T
G
G
5350
A
A
A
A
A
G
A
A
G
G
G
G
G
C
G
G
G
A
C
A
G
T
T
G
G
C
C
G
G
C
G
T
T
C
G
C
C
T
T
T
T
C
G
C
C
A
C
G
T
T
5400
T
C
C
C
A
G
G
G
A
A
T
T
C
C
G
A
G
G
A
C
T
G
G
A
G
A
C
C
G
A
T
C
A
T
T
C
T
A
A
A
A
T
C
A
A
A
G
C
T
G
5450
T
C
C
T
T
C
C
CAC CACAGGCTGC TTGAAGGGAG TCGCGGGCAG GCGGCTGCGC
5500
GTGGAGGTTG GGGACAGCTT GTGGGCTGCG GTGGCGGGGC CTGGTCAGAG
5550
AGGTGCGGCG AGCCTGGGCA GCGGAGCGCA CGGGTCTGGG CCGTGGGGGA
5600
AGGGCGGGCG GGGGGAGAGC AGGCGAGGCA CGAGCGGGGA TCAAAGCGCA
5650
CCCACCCCCC CC
C
GAAAGAG GAAGGGAAAG TGGGTGTTTA TCCCTTGGAT
5700 |
var(5663):[A:0.05]
TTCCCGAGCG ACTGGAGGAG GCGCGGAGGA GGCGCGCACG GGACAGGCCC
5750
CCGCCCCTCC CGGCTGCGCT AG
G
CTCCCAG CGCTGGCGGC ACGTG
C
T
G
T
T
5800 |
var(5773):[A:0.02]
|
NOT SCANNED
T
G
A
A
C
T
G
C
A
G
T
A
A
C
C
C
G
A
A
A
G
C
G
G
A
G
C
C
A
G
C
G
G
G
C
G
G
G
C
C
C
T
A
A
G
C
C
G
C
C
5850
G
G
G
A
G
G
G
A
G
G
C
T
G
C
G
C
G
A
C
C
T
C
T
C
C
C
A
C
T
C
C
A
T
T
T
T
T
T
T
C
C
A
C
T
G
G
G
T
C
A
5900
G
A
G
G
A
C
T
C
A
C
C
C
A
G
G
T
T
T
G
A
A
A
C
C
T
A
A
G
G
A
A
A
G
G
G
A
G
A
G
G
C
A
G
C
C
C
C
C
C
G
5950
T
C
C
C
T
G
A
G
C
G
G
T
G
G
C
A
G
A
C
C
G
G
G
G
A
G
G
T
G
G
G
G
A
G
G
C
G
G
A
C
T
C
C
C
T
C
C
G
T
C
6000
A
G
G
G
G
C
C
G
C
A
T
G
T
G
C
T
G
T
G
G
T
C
T
T
G
G
C
G
A
A
G
G
T
G
G
G
G
A
G
C
G
C
T
C
T
A
C
T
A
G
6050
C
C
G
A
C
G
C
A
T
C
C
T
G
T
A
G
C
A
C
T
T
G
A
C
G
T
T
C
T
C
T
G
A
A
C
A
G
C
C
T
G
T
G
A
A
G
G
G
T
A
6100
A
T
T
C
T
T
A
A
C
G
G
C
A
G
A
C
A
A
A
A
G
A
A
G
G
A
G
C
G
G
T
C
A
A
A
C
C
G
A
G
G
A
G
A
C
T
G
G
G
T
6150
T
G
C
A
T
C
C
C
T
G
C
C
C
C
C
A
C
C
C
C
C
G
T
T
C
C
C
T
T
A
T
A
C
A
G
C
A
T
G
T
A
T
T
T
C
A
G
G
A
A
6200
C
T
G
G
A
A
A
G
G
G
G
C
T
C
C
C
A
A
A
G
T
C
C
T
C
T
C
T
T
C
C
A
T
C
T
G
C
C
C
C
A
C
T
C
C
T
A
G
C
T
6250
G
G
A
A
G
C
A
G
T
T
A
C
C
A
C
A
G
C
C
T
G
G
G
G
G
C
G
G
C
G
G
G
A
G
A
G
G
A
G
T
T
C
T
G
G
G
G
A
G
T
6300
G
G
C
T
G
G
A
A
G
G
G
G
C
T
G
T
A
G
G
C
T
T
C
A
G
A
A
T
G
A
A
G
C
C
T
C
G
G
C
T
T
T
T
C
A
A
A
G
T
T
6350
G
C
G
G
G
C
A
C
T
T
A
T
T
T
T
T
C
C
C
T
C
A
G
C
C
T
T
T
G
C
G
A
C
T
C
C
A
C
C
A
G
A
G
G
C
C
C
A
T
T
6400
C
C
A
A
A
G
A
G
C
G
A
G
G
A
G
A
G
T
G
G
A
G
A
C
T
C
G
G
C
T
C
C
A
A
A
A
G
A
G
A
T
G
G
C
T
G
C
T
T
C
6450
C
T
G
A
T
C
T
C
T
G
C
T
T
T
A
C
A
G
A
G
G
C
T
T
T
G
G
C
C
A
G
A
G
G
G
G
T
A
T
T
A
T
T
G
T
C
C
C
C
T
6500 |
REPEAT
T
T
T
C
A
T
G
G
A
A
G
G
G
G
C
C
A
C
T
G
A
G
G
C
G
T
A
G
A
G
C
G
G
T
T
G
A
A
T
G
A
G
A
C
T
T
G
A
A
C
6550
C
A
G
G
T
C
A
G
G
A
G
A
C
A
A
A
G
A
A
A
A
T
T
T
C
G
G
G
G
A
G
A
G
C
C
T
G
C
A
A
C
A
C
T
G
G
A
C
T
G
6600
C
A
G
C
G
T
C
C
G
T
G
G
G
A
A
T
A
G
T
C
T
C
T
G
G
G
C
C
C
C
G
G
A
G
G
A
G
A
G
T
C
C
T
C
T
T
C
T
G
T
6650
C
C
T
G
C
A
T
G
C
C
T
G
G
G
G
C
T
G
C
T
G
G
A
A
G
C
T
G
G
G
G
T
G
G
A
C
A
G
T
G
A
G
T
G
C
T
A
G
G
A
6700
G
G
A
A
G
G
A
G
G
T
G
T
G
G
C
C
A
G
G
A
C
C
A
G
A
G
T
G
T
G
A
G
A
C
C
C
T
G
G
G
G
T
G
C
A
G
A
G
G
G
6750
C
T
T
T
G
G
G
G
T
G
A
G
G
G
C
G
T
T
G
T
C
T
T
G
G
G
G
T
T
C
C
A
C
C
C
A
C
C
C
T
G
G
G
C
C
T
G
A
C
T
6800
T
G
G
C
C
T
C
G
G
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C
T
A
T
C
T
G
T
A
A
G
G
G
G
C
C
C
T
T
C
A
T
T
G
G
C
C
A
G
12150
C
G
C
T
G
G
T
C
T
C
T
A
G
A
A
G
A
A
G
T
G
C
C
C
C
C
T
C
T
C
A
T
T
C
C
C
C
C
A
A
G
A
C
C
C
T
T
C
A
T
12200
T
T
G
C
C
C
A
A
G
G
G
C
T
G
A
A
C
C
T
G
G
A
A
T
C
C
T
A
A
G
G
A
C
A
T
G
A
G
G
G
T
T
G
G
G
G
G
T
T
G
12250
A
A
G
C
A
A
A
C
A
A
G
C
A
T
T
G
C
C
T
T
T
A
T
C
C
A
T
C
A
C
T
C
T
C
T
G
A
A
G
G
G
A
G
G
C
A
G
T
A
G
12300
T
T
A
G
A
G
T
C
C
C
C
T
G
G
A
A
A
T
T
C
C
C
T
C
G
G
A
C
C
C
C
C
A
A
A
A
C
T
G
G
G
C
A
A
G
G
T
G
T
G
12350
A
A
T
G
A
C
C
C
A
T
C
T
G
G
G
C
T
T
G
G
G
C
T
G
A
C
C
C
A
G
G
C
G
A
C
C
T
C
C
T
A
T
C
G
T
C
C
T
T
C
12400
T
A
C
C
T
C
T
C
A
G
C
T
G
T
C
C
C
T
T
T
G
T
A
G
C
A
G
G
A
G
C
G
G
C
C
C
C
A
A
A
C
A
G
T
A
C
A
G
G
C
12450
C
T
C
T
C
T
G
C
C
C
C
T
C
G
C
C
G
G
C
C
T
C
C
T
G
C
C
C
T
C
C
C
T
C
C
T
T
C
C
C
T
C
C
A
C
C
G
G
G
A
12500
A
T
T
T
C
G
G
A
A
T
G
A
A
A
G
T
G
C
T
A
T
T
G
T
G
A
A
T
G
C
C
T
G
G
C
T
G
G
G
C
C
A
C
T
G
A
A
G
G
G
12550
C
C
A
G
C
A
C
T
G
T
T
A
T
T
T
C
T
G
C
A
A
A
C
C
A
G
C
C
C
T
C
C
C
A
T
T
A
G
C
C
A
T
G
C
A
G
G
G
C
C
12600
T
A
G
G
C
C
A
G
G
A
A
A
A
T
G
T
T
A
C
C
T
T
T
C
C
T
C
C
C
C
G
A
G
C
T
G
A
C
T
G
C
A
G
G
G
G
A
A
A
T
12650
T
C
T
C
A
C
A
T
T
T
A
C
A
G
T
T
T
A
T
G
C
G
G
T
G
G
T
T
G
T
G
T
T
T
G
G
G
G
G
G
G
C
A
G
T
A
G
G
G
G
12700
A
G
G
G
C
G
G
C
G
C
G
T
G
T
G
T
G
T
G
G
T
T
T
G
C
A
T
G
G
G
G
T
G
G
A
G
T
G
G
G
G
G
G
C
T
C
C
C
T
C
12750
T
T
C
T
G
C
A
C
T
G
T
C
C
C
T
C
C
C
C
T
C
C
C
A
G
C
C
T
T
T
G
C
T
T
G
G
T
G
C
T
G
G
T
A
G
C
A
G
G
G
12800
G
T
G
C
T
C
C
C
C
C
T
T
C
T
C
A
T
C
T
G
A
A
C
T
C
T
G
G
T
G
G
G
A
T
G
G
A
C
G
T
T
G
C
T
G
C
T
T
A
T
12850
G
A
G
C
G
A
G
A
C
C
C
A
C
A
G
G
C
T
T
T
T
G
G
T
A
A
A
T
A
A
A
C
T
A
A
C
G
T
G
C
T
C
C
C
C
T
C
T
C
C
12900
T
C
C
A
C
A
C
A
T
G
A
A
A
A
C
C
T
G
T
G
C
G
G
G
G
G
A
G
T
C
C
T
G
G
G
T
G
A
G
G
A
G
G
G
T
G
G
C
A
A
12950
G
G
G
G
G
G
C
T
G
C
G
C
A
G
C
C
A
G
C
C
G
G
G
A
G
G
A
C
G
G
A
G
G
A
C
A
A
G
G
A
G
G
T
G
G
A
A
A
C
A
13000
G
G
A
C
T
C
A
C
T
G
G
C
T
G
C
G
T
A
C
A
G
T
G
G
C
C
C
T
G
G
A
A
G
A
T
G
C
A
G
G
G
A
A
G
T
C
A
C
A
G
13050
G
G
C
T
T
C
T
G
T
T
T
G
T
C
T
T
T
A
T
G
A
T
C
T
T
T
A
G
G
G
G
T
G
G
A
A
A
G
C
C
A
T
T
G
C
C
C
C
C
A
13100
T
C
T
C
C
C
C
C
T
G
C
T
T
T
T
G
G
A
C
C
T
G
G
C
C
A
C
A
C
T
G
A
A
G
A
C
C
T
T
T
T
C
A
T
G
G
C
A
C
A
13150
G
C
T
G
T
T
A
A
T
A
A
A
C
T
T
A
C
T
A
G
A
A
T
C
T
G
C
A
C
C
C
A
G
T
A
G
G
T
G
T
T
T
T
C
C
A
G
C
A
A
13200
G
T
A
A
T
G
A
C
A
A
T
T
T
T
G
G
T
T
C
C
C
A
G
G
A
A
G
T
C
C
T
G
C
T
T
G
A
G
G
T
C
T
A
G
T
C
T
C
A
G
13250
G
C
T
C
T
C
T
T
G
C
T
G
T
A
C
C
C
C
A
T
G
G
A
G
T
A
G
C
T
T
T
C
C
C
T
C
G
A
T
G
G
C
C
T
T
C
C
C
C
T
13300
A
C
T
T
C
C
C
T
G
T
A
C
A
G
T
C
C
A
A
C
G
A
C
T
G
T
G
C
T
C
C
A
C
T
T
C
T
C
C
A
G
G
G
C
A
C
T
T
C
C
13350
G
T
C
C
T
G
T
G
T
C
C
C
G
G
G
ATTCC GAAATGGGCT TCTGCAATGG AAGGGCAGCC
13400
GCCCTGCTCT GGCCCTGCCC AGCCCCCACT TATGCCCCTC ACAAGCCACA
13450
TCCCCCAAAG ACTTGCTGGC AGCTGGCCTG CCCAGCTCCC AAGGCTTTGC
13500
TGTTG
T
GTGG AAGCTGAAGT TCTCTCCAGT CACATTCATT GTTCAGGCAG
13550 |
var(13506):[G:0.02]
AGTGAGGGGC TGGCCAGGGG TGGGCTGTGC CAATCGGCTC ACCCACTTGC
13600
CTCTCTGCCT TCCAG
G
T
C
T
T
C
T
C
C
A
A
G
A
T
C
T
T
C
A
G
C
C
A
C
G
A
G
G
C
C
C
T
G
G
A
13650 | Exon 3
V F S K I F S H E A L E 155
G
A
G
T
T
A
C
C
T
G
C
C
C
A
A
G
A
T
C
C
A
G
C
T
G
G
T
G
A
T
C
C
A
G
G
A
C
A
C
A
C
T
G
C
G
C
G
C
C
T
13700
S Y L P K I Q L V I Q D T L R A 171
G
G
A
G
C
A
G
C
C
A
C
C
C
C
G
A
G
G
C
C
A
T
C
A
A
C
G
T
G
T
A
C
C
A
G
G
A
G
G
C
G
C
A
G
A
A
G
C
T
G
13750 |
var(13727):[A:0.01]
|
var(13740):[T:0.01]
|
var(13741):[A:0.01]
W S S H P E A I N V Y Q E A Q K L 188
A
C
C
T
T
C
C
G
C
A
T
G
G
C
C
A
T
C
C
G
G
G
T
G
C
T
G
C
T
G
G
G
C
T
T
C
A
G
C
A
T
C
C
C
T
G
A
G
G
A
13800 |
var(13758):[A:0.01]
T F R M A I R V L L G F S I P E E 205
G
G
A
C
C
T
T
G
G
G
C
A
C
C
T
C
T
T
T
G
A
G
G
T
C
T
A
C
C
A
G
C
A
G
T
T
T
G
T
G
G
A
C
A
A
T
G
T
C
T
13850
D L G H L F E V Y Q Q F V D N V 221
T
C
T
C
C
C
T
G
C
C
T
G
T
C
G
A
C
C
T
G
C
C
C
T
T
C
A
G
T
G
G
C
T
A
C
C
G
G
C
G
G
GTGAGC
A
CC
13900 |
var(13865):[A:0.01]
|
var(13898):[G:0.01]
F S L P V D L P F S G Y R R 235
CAGGGCCTGG GAGGAGAGGA GCAGGGGCAT CCATGAGCCC CCTCTCTGGG
13950
GGTGGGTGGC TGACCTGACC CCTGAGATGG GCACCTAGGC ACAGGGCACA
14000
TGGACAAAGG GGAGAGGTGT CAGCGTGGGG TAGGAGGAGG CTGGAGTCGT
14050
CCCTGGTGGT CCCGAGGCTC AGATGGGAGC CTGCCCTTCC ATATGAGTGA
14100
CAGCCCTCAC CTCTGCAG
G
G
C
A
T
T
C
A
G
G
C
T
C
G
G
C
A
G
A
T
C
C
T
G
C
A
G
A
A
G
G
G
14150 | Exon 4
G I Q A R Q I L Q K G 246
G
C
T
G
G
A
G
A
A
G
G
C
C
A
T
C
C
G
G
G
A
G
A
A
G
C
T
G
C
A
G
T
G
C
A
C
A
C
A
G
G
G
C
A
A
G
G
A
C
T
14200
L E K A I R E K L Q C T Q G K D 262
A
C
T
T
G
G
A
C
G
C
C
C
T
G
G
A
C
C
T
C
C
T
C
A
T
T
G
A
G
A
G
C
A
G
C
A
A
G
G
A
G
C
A
C
G
G
G
A
A
G
14250 |
var(14204):[C:0.20]
Y L D A L D L L I E S S K E H G K 279
G
A
G
A
T
G
A
C
C
A
T
G
C
A
G
G
A
G
C
T
G
A
A
G
GTGGGG TGGGCGTGTG CCCCTCAC
G
G
14300 |
var(14299):[T:0.20]
E M T M Q E L K 287
GCAGCACCAG CACCCAGGCT CCATTCTGAG CTTTCCCTGG GTGGAAATGT
14350
GCCCAGCCAT TTCTACCCCC TGTAGTCTGG CCCCACACAT GCTTTCTGAG
14400
CAGTGGCTGG AGACCTTGAA ACTGGAAGCG AAGTCTGTGT CCCCACCCCT
14450
GCTGTGCAGG ATGC
C
GTGGG GCACCCTCCC TTCTCTCCCC
A
ATGGCCTGC
14500 |
var(14465):[T:0.09]
|
var(14491):[:0.99]
AGGGAGCTCA GGCCTGGGAA TGATCTCAGT TCATTTCCTA GTCCCAATAT
14550
CCCTGGAAGG CCATCTAGGG AAAGGCAGGC CCACAAGGGG AAACCACTTG
14600
CTTGTCACCA GCCTCAGCCC TTGGGGAAG
A
GCAGGGGAGA TTTGGATGTG
14650 |
var(14630):[G:0.01]
AGGTATCCT
C
CCCCACCCCC AGCCTTTTCA GGTTGCTGGC GCCTTGCATG
14700 |
var(14660):[T:0.09]
CCCTCCCACC CTCCCCCC
C
G CCCCC
T
AGGC CCCTGGGGAT CCCGGCTGTG
14750 |
var(14719):[G:0.02]
|
var(14726):[C:0.09]
CTCCACGCAG GACCTGCTTG CCCTGCTTTA GGCGGATGTT TCACC
C
GAGG
14800 |
var(14796):[T:0.01]
AGGGCTCACT CGCCCATCCC CACCTGGGCT CTGCAGGCCT GCTCCACTGC
14850
TGGGTGC
C
CA TGGACACTCA CTGCAGCCTC CCCTGCCCAC TATCTTTGCC
14900 |
var(14858):[T:0.01]
TCCCCATATT CTAGCTCCA
A
CTTCTTTCCT GGGGAGCTAG GAAGAGCTGG
14950 |
var(14920):[G:0.04]
AGTGGCTTTT CCACTACAAG AAGCTTTGTG ATTTATGGA
T
GTTGCCATGG
15000 |
var(14990):[C:0.01]
CCAGTAATGG ACC
C
A
G
G
T
C
C
C
T
T
C
A
T
T
G
C
C
C
T
C
T
C
T
G
G
G
C
C
C
A
G
A
G
T
C
C
A
15050 |
REPEAT
|
var(15044):[A:0.01]
C
A
T
T
T
G
T
A
A
A
A
T
G
C
A
G
G
G
T
G
T
G
C
T
A
T
G
A
G
A
T
A
G
C
C
T
G
C
T
G
G
G
G
C
C
T
T
T
C
T
15100
GTGGGGAACC CATGGCCCTG GTGTCCTGCT CCCCAGAAAG CCCTGGCGGG
15150
GTCTTTAGGT CCTCTGGGGG TCGCCTTCCC TCAGCCTCAT CCCAGGTCTC
15200
CAGGGGAGTG GCCCCAGGCT CCCTCCCAGA CCCCATTGGC TCCCCTGATC
15250
ACCCACTGAA TGTCCTCCTC CTGCGATGGA GGAAGGGGCT GGCACTGGGA
15300
GTGGGAAGGC CCGGGTTTAG ACTCACATCC CCCACACATA CACACGCACA
15350
CCTGCTGCGC AGGGCCTGG
C
TCCTTGGGAT TTGTTCTTTT TCTCCTGTGA
15400 |
var(15370):[T:0.20]
GCCCACTGCA TATCAGGCCT GTGGGGCTGG CCCAGGAACC CAGCAGTGAG
15450
TGAGAAGTGG CTCCACTCCA AGGGACTCTA GGCCAGTGCT TCTGCCCTCG
15500
GTCACAGCAG TTGTGTCTTC TGCCCAGCTA GGGACTGGCT GTGACCCCCG
15550
TGTCCATCGT GACACTAATG CCCCGGCAAC ATGAAGCTCA GAGGAAGCAG
15600
AATTCACTGC AGGAACCAGG CAG
G
GCCCAG CACAGATGAC CTGGGCACAC
15650 |
var(15624):[T:0.01]
GGGCCACTGA CTGAATGGGG CGGCCCCTGC CTGGCTGAAC CCACACCTCC
15700
AACAACACCT CTCCTCTGTG CCCTGCAG
G
A
C
G
G
G
A
C
C
C
T
G
G
A
G
C
T
G
A
T
C
T
15750 | Exon 5
D G T L E L I 294
T
T
G
C
G
G
C
C
T
A
T
G
C
C
A
C
C
A
C
G
G
C
C
A
G
C
G
C
C
A
G
C
A
C
C
T
C
A
C
T
C
A
T
C
A
T
G
C
A
G
15800
F A A Y A T T A S A S T S L I M Q 311
C
T
G
C
T
G
A
A
G
C
A
C
C
C
C
A
C
T
G
T
G
C
T
G
G
A
G
A
A
G
C
T
G
C
G
G
G
A
T
G
A
G
C
T
G
C
G
G
G
C
15850
L L K H P T V L E K L R D E L R A 328
T
C
A
T
G
G
C
A
T
C
C
T
G
C
A
C
A
G
T
G
G
C
G
G
C
T
G
C
C
C
C
T
G
C
G
A
G
G
G
C
A
C
A
C
T
G
C
G
C
C
15900
H G I L H S G G C P C E G T L R 344
T
G
G
A
C
A
C
G
C
T
C
A
G
T
G
G
G
C
T
G
C
G
C
T
A
C
C
T
G
G
A
C
T
G
C
G
T
C
A
T
C
A
A
G
G
A
G
G
T
C
15950
L D T L S G L R Y L D C V I K E V 361
A
T
G
C
G
C
C
T
G
T
T
C
A
C
G
C
C
C
A
T
T
T
C
C
G
G
C
G
G
C
T
A
C
C
G
C
A
C
T
G
T
G
C
T
G
C
A
G
A
C
16000
M R L F T P I S G G Y R T V L Q T 378
C
T
T
C
G
A
G
C
T
T
G
A
T
GTGAGGC TGGGCCCGTG GCACCGGGGG CGATGGGGGA
16050 |
var(16005):[A:0.01]
F E L D 382
GCAGGGGCAC CGGGATAGGG GCAAGGCGGG GCACCAGCCT CCATTTCA
G
G
16100 |
var(16099):[C:0.01]
GACTTCAGGC CTGATGGG
G
A
A
A
C
A
G
T
G
C
T
T
G
C
T
T
T
C
A
G
G
G
A
G
C
T
T
T
C
A
G
T
16150 |
REPEAT
C
C
G
A
T
G
G
G
A
G
A
AGTGCGCCC CAAATGCATC AGGTGAAGCC AAGTTGGGTG
16200
TCATATGTGA AGTCACATGT GCACATCTAC AGATAAGGGC TTGGACTAAC
16250
ATGCTGAATG GGGCAGGCTG GCCAGGCCTT GGGGGCCACA GTGGGGT
G
TC
16300 |
var(16298):[A:0.01]
TCTAAGAAAA GGCAGGTCTT GAACATCTGG GGCTGAGCAG GGAGGGGGCA
16350
GTCCTGGGCC CTCTGTGGGC TCCTCTGGCT CTCACCACCC ACTCCT
C
GGC
16400 |
var(16397):[T:0.01]
CCCCATCTTG CTCCAG
G
G
T
T
T
C
C
A
G
A
T
C
C
C
C
A
A
A
G
G
C
T
G
G
A
G
T
G
T
C
A
T
G
T
16450 | Exon 6
G F Q I P K G W S V M 393
A
T
A
G
C
A
T
C
C
G
G
G
A
C
A
C
C
C
A
T
G
A
C
A
C
A
G
C
G
C
C
C
G
T
G
T
T
C
A
A
A
G
A
C
G
T
G
A
A
C
16500
Y S I R D T H D T A P V F K D V N 410
G
T
G
T
T
C
G
A
C
C
C
C
G
A
T
C
G
C
T
T
C
A
G
C
C
A
G
G
C
G
C
G
G
A
G
C
G
A
G
G
A
C
A
A
G
G
A
T
G
G
16550 |
var(16529):[G:0.03]
V F D P D R F S Q A R S E D K D G 427
C
C
G
C
T
T
C
C
A
T
T
A
C
C
T
C
C
C
G
T
T
C
G
G
T
G
G
C
G
G
T
G
T
C
C
G
G
A
C
C
T
G
C
C
T
G
G
G
C
A
16600
R F H Y L P F G G G V R T C L G 443
A
G
C
A
C
C
T
G
G
C
C
A
A
G
C
T
G
T
T
C
C
T
G
A
A
G
G
T
G
C
T
G
G
C
G
G
T
G
G
A
G
C
T
G
G
C
T
A
G
C
16650 |
var(16647):[C:0.14]
K H L A K L F L K V L A V E L A S 460
A
C
C
A
G
C
C
G
C
T
T
T
G
A
G
C
T
G
G
C
C
A
C
A
C
G
G
A
C
C
T
T
C
C
C
C
C
G
C
A
T
C
A
C
C
T
T
G
G
T
16700 |
var(16687):[T:0.01]
T S R F E L A T R T F P R I T L V 477
C
C
C
C
G
T
C
C
T
G
C
A
C
C
C
C
G
T
G
G
A
T
G
G
C
C
T
C
A
G
C
G
T
C
A
A
G
T
T
C
T
T
T
G
G
C
C
T
G
G
16750 |
var(16705):[A:0.01]
P V L H P V D G L S V K F F G L 493
A
C
T
C
C
A
A
C
C
A
G
A
A
C
G
A
G
A
T
C
C
T
G
C
C
G
G
A
G
A
C
G
G
A
G
G
C
C
A
T
G
C
T
G
A
G
C
G
C
C
16800
D S N Q N E I L P E T E A M L S A 510
A
C
A
G
T
C
T
A
A
C
C
C
A
A
G
A
C
C
C
A
C
C
C
G
C
C
T
C
A
G
C
C
C
A
G
C
C
C
A
G
G
C
A
G
C
G
G
G
G
T
16850 |
UTR
T V 512
G
G
T
G
G
T
T
G
T
G
G
G
A
G
G
T
A
G
A
A
A
C
C
T
G
T
G
T
G
T
G
G
G
A
G
G
G
G
G
C
C
G
G
A
A
C
G
G
G
G
16900 |
var(16853):[C:0.19]
A
G
G
G
C
G
A
G
T
G
G
C
C
C
C
C
A
T
A
C
T
T
G
C
C
C
T
C
C
C
T
T
G
C
T
C
C
C
C
C
T
C
C
C
T
G
G
C
A
A
16950
A
C
C
C
T
A
C
C
C
A
A
A
G
C
C
A
G
T
G
G
G
C
C
C
C
A
T
T
C
C
T
A
G
G
G
C
T
G
G
G
C
T
C
C
C
C
T
T
C
T
17000
G
G
C
T
C
C
A
G
C
T
T
C
C
C
T
C
C
A
G
C
C
A
C
T
C
C
C
C
A
T
T
T
A
C
C
A
T
C
A
G
C
T
C
A
G
C
C
C
C
T
17050
G
G
G
A
A
G
G
G
C
G
T
G
G
C
A
G
G
G
G
C
T
C
T
G
C
A
T
G
C
C
C
G
T
G
A
C
A
G
T
G
T
T
A
G
G
T
G
T
C
A
17100
G
C
G
C
G
T
G
C
T
A
C
A
G
T
G
T
T
T
T
T
G
T
G
A
T
G
T
T
C
T
G
A
A
C
T
G
C
T
C
C
C
T
T
C
C
C
T
C
C
G
17150 |
var(17104):[T:0.01]
T
T
C
C
T
T
T
C
G
G
A
C
C
C
T
T
T
T
A
G
C
T
G
G
G
G
T
T
G
G
G
G
G
A
C
G
G
G
A
A
G
A
G
C
C
G
T
G
C
C
17200 |
var(17158):[T:0.01]
|
var(17169):[G:0.01]
|
var(17177):[A:0.01]
C
C
C
T
T
G
G
G
C
G
C
A
C
T
C
T
T
C
A
G
C
G
T
C
T
C
C
T
C
C
T
C
C
T
G
C
G
C
C
C
C
C
A
C
T
G
C
G
T
C
17250 |
var(17206):[T:0.21]
|
var(17238):[T:0.01]
T
G
C
C
C
A
G
G
A
A
C
A
G
C
A
T
C
C
T
G
G
G
T
A
G
C
A
G
A
A
C
A
G
G
A
G
T
C
A
A
C
C
T
T
G
G
C
G
G
G
17300
G
C
G
G
G
G
G
C
T
G
C
G
T
C
C
A
A
C
C
T
G
G
A
G
A
T
T
G
C
C
C
T
T
C
C
C
T
A
T
G
C
C
A
C
G
G
T
T
C
C
17350 |
var(17311):[T:0.02]
C
A
C
C
C
T
C
C
C
T
C
A
C
C
A
G
T
T
T
G
G
A
C
A
A
T
T
T
G
A
A
A
T
T
A
C
C
T
A
T
T
G
C
T
G
C
T
A
C
T
17400
T
G
T
T
C
T
G
T
C
C
T
C
T
G
A
C
C
T
T
G
G
G
G
C
A
A
A
G
G
A
G
C
C
C
C
A
G
G
C
C
C
T
G
T
C
T
C
C
C
C
17450
A
G
C
A
T
C
C
T
C
C
C
T
G
G
T
G
G
C
C
C
T
G
G
G
C
A
G
G
T
G
C
A
C
T
G
A
C
A
C
C
C
C
C
A
C
C
T
T
C
C
17500
C
A
T
C
C
C
C
T
G
C
T
G
A
A
C
C
A
G
G
C
C
C
T
G
T
T
A
C
A
C
A
C
A
G
C
C
G
C
C
T
A
A
G
G
C
C
C
G
C
G
17550
G
C
T
C
A
T
G
T
G
C
T
G
C
C
C
G
C
C
C
C
C
A
T
A
T
T
T
A
T
T
C
A
C
T
G
A
T
A
G
A
G
A
A
T
C
T
T
G
G
G
17600
G
A
T
G
C
T
G
G
G
G
T
C
T
G
G
A
G
T
G
A
A
C
A
T
C
T
C
C
T
C
C
C
C
T
T
C
A
T
G
C
C
C
T
A
G
C
C
T
G
T
17650 |
var(17620):[G:0.01]
G
T
T
C
T
A
G
C
T
G
T
C
C
T
G
G
C
G
A
G
A
C
T
T
C
T
G
T
G
A
G
T
G
A
A
G
A
G
G
A
A
G
G
G
G
T
C
T
C
T
17700
G
G
T
C
A
A
A
C
C
C
A
G
C
C
C
C
C
A
G
G
G
C
C
T
A
G
G
G
T
T
G
A
A
A
G
C
C
T
T
C
C
C
C
G
G
C
T
C
C
G
17750 |
REPEAT
G
G
C
A
T
T
A
T
T
T
G
G
G
T
T
T
A
A
T
C
T
C
G
G
A
G
C
C
T
C
A
C
T
C
C
T
G
G
A
C
T
G
A
A
G
T
C
C
G
G
17800
T
G
C
C
T
C
T
G
C
C
T
T
A
T
C
C
C
T
G
G
T
G
G
A
G
A
T
G
G
A
A
T
G
T
G
G
C
C
C
A
T
T
G
C
C
T
C
C
T
C
17850
C
C
T
C
T
C
C
T
G
T
C
A
A
A
A
A
C
C
C
T
G
A
T
C
A
G
G
T
A
G
A
T
T
T
G
G
A
G
G
C
G
G
C
C
A
C
G
A
T
T
17900 |
var(17890):[T:0.04]
T
C
C
T
G
T
T
T
G
G
C
C
C
C
T
G
T
T
C
A
C
C
C
C
A
G
T
G
C
A
C
T
G
G
C
C
C
T
G
A
C
T
C
C
A
G
G
C
G
T
17950
G
A
G
T
A
T
G
G
G
G
A
A
G
G
A
T
A
C
G
G
G
T
T
C
T
T
C
T
G
A
C
G
G
G
G
A
G
C
A
A
G
G
G
C
C
T
C
C
G
T
18000
C
T
T
C
C
C
T
T
C
C
T
T
A
A
C
T
C
T
C
C
C
C
C
T
T
T
G
C
C
C
T
C
C
G
C
C
C
T
G
A
A
A
A
A
G
G
T
G
T
C
18050 |
var(18034):[A:0.01]
C
T
T
G
A
A
G
T
C
C
C
T
T
C
C
A
C
C
T
C
T
A
T
G
C
C
A
C
T
G
T
C
T
G
C
T
T
A
G
C
C
C
A
G
C
T
C
A
G
G
18100
G
G
T
G
G
G
G
A
A
G
A
G
G
C
G
A
A
A
G
C
G
T
G
G
G
G
G
A
G
G
T
G
A
G
C
G
C
A
G
C
G
G
C
A
G
T
T
C
T
G
18150 |
var(18148):[T:0.01]
C
C
T
C
G
G
A
G
C
T
G
A
T
T
G
C
A
G
G
G
C
C
C
T
G
T
G
T
G
G
T
C
T
C
C
G
G
A
C
A
G
C
T
G
C
G
G
G
A
A
18200 |
var(18155):[A:0.01]
G
G
C
T
G
C
C
G
C
A
G
C
T
G
A
A
G
C
T
G
A
A
G
A
G
G
C
G
G
C
T
A
C
G
T
G
C
G
G
T
T
T
G
T
C
A
G
G
G
G
18250
G
A
T
T
G
G
G
T
T
G
A
A
A
A
C
T
G
G
C
C
A
G
T
C
G
G
G
A
T
G
A
C
T
G
G
G
T
G
A
A
A
G
A
G
G
A
G
T
A
G
18300
C
T
C
C
T
G
C
C
A
C
T
G
G
C
G
T
T
T
T
G
A
G
T
G
T
T
G
G
C
A
A
T
T
T
G
G
G
A
T
G
C
C
T
C
C
T
G
G
G
G
18350 |
var(18314):[T:0.01]
A
A
G
G
T
T
T
C
C
G
G
G
C
G
T
T
T
G
G
T
G
A
G
T
C
T
C
T
A
G
A
T
T
T
T
T
C
C
T
T
G
C
T
T
T
C
T
G
T
G
18400
T
T
T
A
T
T
G
G
T
T
T
T
T
G
A
T
G
T
T
G
T
A
A
A
A
G
C
A
A
T
G
A
A
T
C
C
C
C
T
T
T
A
C
A
A
G
A
A
A
A
18450
T
C
G
A
A
A
A
C
A
C
A
G
A
A
G
A
A
T
G
A
A
G
G
A
C
A
T
G
C
C
A
G
T
C
C
C
C
G
A
T
C
G
C
T
G
C
T
G
T
G
18500 |
var(18452):[T:0.01]
A
G
C
A
C
C
T
C
A
G
T
G
G
C
T
C
C
C
T
C
A
G
A
C
C
A
G
A
T
C
C
C
G
T
A
G
G
C
A
G
C
C
C
C
A
C
A
G
A
C
18550 |
var(18514):[T:0.01]
C
G
A
C
C
C
T
G
A
C
C
C
C
A
C
T
C
A
C
A
G
C
C
A
C
C
C
T
G
A
A
G
A
T
A
G
A
C
T
A
T
A
G
G
A
A
C
G
G
G
18600
C
C
C
A
T
A
C
C
A
C
A
C
A
G
A
C
T
G
C
T
C
T
C
C
A
A
T
C
C
C
T
G
A
G
T
C
T
C
A
G
A
T
G
T
T
T
C
A
T
T
18650 |
var(18635):[G:0.01]
T
A
T
T
T
C
C
T
A
C
T
T
T
T
C
C
A
C
T
A
C
T
A
A
A
A
A
A
C
A
G
T
G
T
G
G
A
A
T
A
G
A
C
A
T
T
A
T
T
G
18700
G
C
A
A
A
A
T
T
G
C
T
C
A
T
C
C
C
T
A
A
T
C
C
T
G
A
A
A
A
A
C
A
G
G
C
C
A
G
A
A
T
G
G
G
T
A
A
A
G
A
18750 |
var(18710):[G:0.19]
C
T
T
G
T
C
A
A
A
G
C
T
T
G
C
A
A
C
A
T
A
G
C
T
A
C
A
T
G
G
T
G
C
A
C
C
C
G
G
A
C
C
T
G
T
A
C
C
C
C
18800
C
T
C
C
C
C
C
C
A
A
C
A
C
A
A
A
A
C
C
A
G
T
G
T
C
T
G
G
G
A
G
G
T
T
C
A
T
T
T
T
C
C
T
T
T
A
A
A
C
T
18850 |
var(18829):[A:0.19]
G
A
T
C
C
A
G
C
T
G
G
C
C
C
T
G
A
A
C
C
A
A
T
T
G
T
T
T
T
T
G
A
C
T
G
A
G
T
A
T
C
T
A
G
G
A
G
A
G
C
18900
A
G
T
A
A
G
T
G
G
A
A
C
T
T
C
A
G
A
C
A
A
G
C
C
C
A
C
T
G
G
G
T
C
T
G
G
T
C
C
A
G
G
T
G
A
G
G
G
G
C
18950
A
G
G
G
G
G
C
A
T
G
G
G
G
C
T
G
G
G
A
G
G
T
C
T
C
A
G
G
G
G
C
C
T
T
C
C
C
T
G
G
G
G
G
T
G
G
C
C
A
G
19000
C
C
T
G
G
T
A
G
G
G
G
G
C
A
G
A
G
A
A
G
G
A
A
A
A
G
C
T
G
A
G
G
G
G
G
G
T
C
C
C
T
G
T
G
A
G
G
G
A
G
19050
G
A
A
A
G
A
A
G
G
A
T
C
A
T
T
T
G
C
C
C
C
G
C
T
G
G
G
T
C
T
C
A
A
A
G
G
C
A
G
T
G
A
G
A
A
G
A
G
A
G
19100
C
T
G
A
A
G
A
A
A
G
C
T
C
T
G
G
C
T
G
G
C
T
G
A
C
A
G
G
A
T
C
C
C
T
G
T
G
T
T
G
T
A
A
T
T
G
G
T
C
C
19150
C
T
C
C
T
T
T
C
A
G
C
T
C
T
C
T
A
G
T
G
A
G
A
T
G
C
C
C
G
T
G
T
C
T
G
T
G
C
G
T
G
T
G
C
G
T
G
T
G
C
19200 |
var(19188):[:0.76]
G
T
G
T
G
T
G
T
T
T
C
A
T
A
C
A
G
C
T
A
G
C
A
T
T
A
G
A
T
G
G
G
T
G
A
T
G
T
T
T
C
T
T
A
C
T
T
A
T
C
19250
A
T
C
C
C
T
A
A
C
T
A
T
T
G
C
A
A
C
T
T
G
A
C
C
T
T
A
A
A
A
A
G
A
C
A
A
A
A
C
C
C
C
A
C
A
A
A
A
C
T
19300
C
T
T
C
C
T
G
C
C
A
C
G
G
G
C
T
T
G
C
A
G
A
T
T
G
A
A
G
C
A
C
T
T
T
C
G
A
T
G
T
T
G
G
G
C
G
C
T
G
G
19350
C
G
T
T
T
G
T
G
T
T
C
T
G
G
G
C
A
C
C
A
C
C
G
T
G
A
C
C
C
T
G
C
C
C
A
G
A
T
G
G
C
T
A
T
A
A
T
A
T
T
19400 |
var(19372):[T:0.01]
A
T
T
T
T
A
T
A
C
A
C
A
A
A
C
C
T
T
T
T
T
T
T
T
C
C
A
T
A
A
A
T
G
T
T
A
T
A
A
T
T
T
T
G
T
G
T
C
T
G
19450 |
var(19425):[:0.62]
T
C
T
T
T
A
T
A
A
A
C
T
A
T
T
A
T
A
A
G
T
A
C
T
A
T
T
T
T
T
G
T
T
A
T
A
A
T
T
C
A
A
A
A
T
A
G
A
T
A
19500 |
var(19481):[:0.01]
T
T
T
A
G
T
A
T
A
A
A
G
T
T
T
T
T
G
C
T
G
T
T
A
A
A
T
A
T
T
T
G
T
T
A
T
T
T
A
G
T
A
A
A
C
T
A
T
G
A
19550 |
var(19545):[A:0.47]
A
T
T
T
T
G
C
T
C
T
A
T
T
G
T
A
A
A
C
A
T
G
G
T
T
C
A
A
A
A
T
A
T
T
A
A
T
A
T
G
T
T
T
T
T
A
T
C
A
C
19600
A
G
T
C
G
T
T
T
T
A
A
T
A
T
T
G
A
A
A
A
A
G
C
A
C
T
T
G
T
G
T
G
T
T
T
T
G
T
T
T
T
G
A
T
A
T
G
A
A
A
19650
C
T
G
G
T
A
C
C
G
T
G
T
G
A
G
T
G
T
T
T
T
T
G
C
T
G
T
C
G
T
G
G
T
T
T
T
A
A
T
C
T
G
T
A
T
A
T
A
A
T
19700 |
var(19661):[C:0.01]
A
T
T
C
C
A
T
G
T
T
G
C
A
T
A
T
T
A
A
A
A
A
A
A
T
G
A
A
T
G
T
T
G
T
G
C
A
T
T
T
T
G
T
G
A
T
T
T
T
G
19750 |
var(19723):[C:0.44]
|
var(19725):[C:0.02]
G
A
A
A
T
A
C
T
C
A
A
T
G
T
G
G
C
T
C
T
T
C
T
A
T
A
G
G
C
T
T
C
T
A
G
A
A
T
A
A
A
C
C
G
T
G
G
G
G
A
19800
C
C
C
G
C
CCTTG TCTCCGTTGC
G
TCTCTGCTC TCTGCCTTC
C
CAGCCTTACT
19850 |
var(19802):[T:0.11]
|
var(19821):[C:0.40]
|
var(19840):[T:0.01]
GAAAGAGTCC TCCCCGGC
T
A CCTGTGTTCA
C
ATCAGCAGT GCCCATCCAC
19900 |
var(19869):[C:0.13]
|
var(19881):[T:0.01]
CTTGTCA
G
TT AGGAAGCTCT TCCCTAAGAC CGTCCCGTGA GGCCAGTTCG
19950 |
var(19908):[C:0.12]
CCATTCCTTG CATGC
G
GGCA CAGAGG
C
CTG TGACAGAGTC C
T
GGGAGGAG
20000 |
var(19966):[A:0.01]
|
var(19977):[T:0.35]
|
var(19992):[C:0.03]
GAGGTTCCCT GGGGAGGGAG AGAGAGAACC GGTCAGCCTA TTGGGGGAGG
20050
GGCAGCTGGG AGGATGCTC
C
GAGTGTGGCT GTGGCTGG
C
T GTGCCAGGTG
20100 |
var(20070):[T:0.01]
|
var(20089):[:0.01]
TTTCGAGGCT GGACAGGGGG AC
C
GAGAGCT CTGAGCCTGT CTTGTTAACT
20150 |
var(20123):[G:0.01]
TGAGTGAGGA CACTGATGTT CACAGTCAC
G
TGGCAAATTA GGGAGCAGAA
20200 |
var(20180):[A:0.01]
TTCAGTTCTT CTGACGTCTG GGCTCGCGTC CCATGCCAGC ACTTCTCAAA
20250
GCCTGTTTCA TGGGTGTTGT GGGATCAGAT AGA
T
T
C
C
A
T
G
A
T
C
A
A
A
T
G
A
G
20300 |
REPEAT
T
T
T
G
G
G
A
A
A
T
G
G
G
T
T
A
A
A
C
A
C
A
G
T
C
A
T
C
C
C
G
G
T
T
C
C
C
C
T
T
C
T
G
C
A
G
G
C
C
T
20350 |
var(20338):[A:0.02]
T
G
T
C
A
G
A
A
C
C
C
T
GAGCCCCA GGATGTGTAG CCTCAGGGGC AGTAGAGTGT
20400 |
var(20360):[G:0.01]
GGGGTGAACA CAGGCTGCAG CATTCTCCAG GCCTATTTGA GGACTGAAAC
20450
CCTGTCCTCT TTCGCCGATG ATCACATTTC ATGGAAAGAT CCACAGCCTG
20500
ACTGTCACAG AGGCCTGA
G
G CGAGGACCCG TGATGGGCAC GACTTTCAGT
20550 |
var(20519):[A:0.01]
GCTGAGAAAA CCCCAGGTGG TTCCCGGGAT TGAGGGGCTG TGGGTGGGGA
20600
GGGAGGGCAA TGAGAGACAG AGCTTCGGCC CCTGGAGCTG CACACTGGGA
20650
AC
C
G
GGAAAG GCTGCAGCGT GACCAGGCTG GCCCCAGCCT CTGCCCC
G
CC
20700 |
var(20653):[T:0.01]
|
var(20654):[A:0.42]
|
var(20698):[A:0.01]
C
G
GGTCCCAT CCCCATAGCC TGAGGGGGAA GGCCCACCCC TGAGCTGACC
20750 |
var(20702):[A:0.09]
TGAGAAGAGC CTTTTTGCG
G
CTGCAGC
G
TT TCTTTTCCAT ACAGTCAGTC
20800 |
var(20770):[C:0.01]
|
var(20778):[A:0.03]
AGACC