Hugo        AllelePos a.a.Pos Residue   Variant   ADfreq    EDfreq    PPHpredict              SIFTpredict   
ache        004157    34      R         Q         0.04      0.00      benign                  TOLERATED     
ache        004459    135     P         A         0.00      0.02      probably damaging       INTOLERANT    
ache        005113    353     H         N         0.02      0.05      benign                  INTOLERANT    
ache        007252    592     P         R         0.13      0.39      probably damaging       INTOLERANT    
ache        007272    599     P         T         0.00      0.02      unknown                 TOLERATED