ABCG2 Color FASTA
The longest form of insertion/deletion sites is shown in the FASTA sequence and contain a '-' as the alternate allele in the variation tag.
*Display courtesy of
GeneSNPs
TCTATGTATA GGGTTTTGAT TTGTTTTTAC TTTGCATAAT TACAGAATGC
50
TATATTCAAC TAAGTATCCA TTTTTAAAAA TGTGCTTCAT ATCAGTTTCG
100
TGTGTGTTTT CTCCATTTTT GTTCAGTCTC CTCCTGTAGT GCCTTCAGAT
150
CTTGCTGGAA ATGTTTTCAT TTTTTCTGGT ATCATAAAAT TTTATTCTTT
200
TCACTTATCT GGGTGAGCTA AAAAGAAAAT TAAAATAAAA TTTATTTTTC
250
GGAGATTTTT CAGTTTTTGC AAACAGTC
A
T TAACGGCCAG GTCTGAAAAC
300 |
var(279):[G:0.13]
TTTATCTTAA
T
T
T
T
T
T
T
T
T
T
T
T
T
T
C
T
T
G
A
G
A
C
A
G
A
G
T
C
T
C
A
C
T
C
T
G
T
G
G
C
350 |
REPEAT
|
var(324):[:0.89]
C
C
A
G
G
C
T
G
G
A
G
T
G
C
A
G
T
G
G
T
G
G
G
A
T
C
T
C
G
G
G
T
C
A
T
T
T
G
C
A
A
C
C
T
C
T
G
C
C
T
400
C
C
T
G
T
G
T
T
C
A
A
G
C
G
C
T
T
C
T
T
G
T
T
C
C
T
T
A
G
C
C
T
C
G
C
G
A
G
T
A
G
C
T
G
G
G
A
T
T
A
450 |
var(413):[T:0.05]
C
A
G
C
C
T
C
G
C
C
A
C
C
A
C
A
C
C
C
A
G
C
T
A
A
C
T
T
T
T
G
T
A
T
T
T
T
T
A
G
T
A
G
A
G
G
C
A
G
G
500 |
var(467):[T:0.02]
G
T
T
T
C
A
C
C
A
T
G
T
T
G
G
C
C
A
G
G
C
T
G
G
T
C
T
C
G
A
A
C
T
C
C
T
G
G
C
C
T
C
A
A
G
T
G
A
T
C
550
T
G
C
C
T
G
C
G
T
C
A
G
C
C
T
C
C
C
A
A
A
G
T
G
C
T
G
G
G
A
T
T
A
C
A
G
G
C
A
T
G
A
G
C
C
A
C
C
G
T
600
G
C
T
G
G
C
C
TTA ATTTTGTCTT AAAATGAAGT ATGACTAACA TGTATTTCTA
650
TATGGGCCTT TAAGGGTCTT GAAACTGACA GAAATTAATT CAAAAGAATA
700
ATTTTACCCA AATGTTTGGG CGCATCATGA ATATATACCT TAAAATTCTT
750
TTAAAAAGCA TGCGGTATGG TATATTTAAA ATTCTTTTTA AAAAATTATG
800
TATAGTCAAT TTTCTTATCT AGGCTTCCTA GCTAAAACTT TCCTGCATTG
850
GGTGAACCAT TAATAGTTAT TCCTAGTGTT GATTTAAACA ACTTAAATGA
900
TACTATGATT TTTGTTTGTA AATGCAAACC AGAAAATATC TGCATGCAGG
950
TACTAATTTC CTAGGGTAGA TGCAGCAGGT AGATGTTGGG ATGGCTACAC
1000
TCAC
T
C
A
C
AA AGCCTGATGG CCCGTTTCCT GAAC
A
TGC
G
C AATCACTTTC
1050 |
var(1005):[:0.73]
|
var(1035):[G:0.13]
|
var(1039):[A:0.01]
TAGCCTTTCC ACACCATCGG AATATTGCAC AGAAGTATGT CAGTCACAGG
1100
AGTGTAAAGA ATAACATTTA AACTATGGTA ATATTTTCAT TCAGTAAGTT
1150
TCTCCCCTTT CCTTCCTTGG GTTAGATTCA GTGCCTGATT TTTTTAGGCC
1200
CTGGGGCGCA AGCATCCACT TTCTCAGAAT CCCATTCACC AGAAACCACC
1250
CATTTAACTT GCTCTGGGTG CGAGCAGCGC TTGTGACTGG GCAACCTGTG
1300
CGTCAGCGTC CCCGGTGCTT CGG
C
GCTCCG GCCAGTGACG GCGACCAAAC
1350 |
var(1324):[A:0.02]
CCAGCTAGGT CAGACGAGGT ACT
G
ATCAGC CCAATGAGCG CCTGGTGATT
1400 |
var(1374):[C:0.01]
CTCGTAGTTA ATCACTCTGG TTCATTCCGT TCGATCCCGG AGGCGGGAGT
1450
GTTTGGCTTG TCCCTGCGTG TCACGGCAGG GTGACCCTAG CCCCGAGGGA
1500
GGGCGGTGGT ACCAGTCCTG CTGGCGGCTC AGCGCGGCAG GACACGTGTG
1550
CGCTTTCAGC CGGGTCGCAG GGCGCTTATC GCGGCCCGGC AGTCGGGGCC
1600
ACGCCTCACC CCCGCCCGCG AACCCCGACC TGGGGAAACC CGGGGCGCTG
1650
GGGAGGGGCC ACTGCGTTCA GCTCTGGCGG TCCACAGCCC GAAGCGCGGC
1700
TTAGGAAGTT CGT
G
T
C
A
G
C
G
C
T
G
C
C
T
G
A
G
C
T
C
G
T
C
C
C
C
T
G
G
A
T
G
T
C
C
G
G
G
1750 | Exon 1 |
UTR
T
C
T
C
C
C
C
A
G
G
C
G
G
C
C
A
C
C
C
G
C
C
G
G
C
T
C
C
C
A
T
C
G
T
G
A
C
C
T
C
C
A
G
C
C
G
C
A
G
C
1800
G
C
C
T
C
C
C
A
C
G
C
C
G
G
C
C
G
C
C
G
C
G
C
G
A
G
G
G
G
A
G
C
G
C
T
C
G
G
G
C
G
C
G
C
C
G
G
G
T
G
1850
T
G
G
T
T
G
G
G
G
G
A
A
G
G
G
G
T
T
G
T
G
C
C
G
C
G
C
G
C
G
G
G
C
T
G
C
G
T
G
C
T
G
T
G
C
C
C
A
C
T
1900
C
A
A
A
A
G
G
T
T
C
C
G
G
G
C
G
C
G
C
A
G
G
A
G
G
G
A
A
G
A
G
G
C
A
G
T
G
C
C
C
G
C
C
A
C
T
C
C
C
A
1950
C
T
G
A
G
A
T
T
G
A
G
A
G
A
C
G
C
G
G
C
A
A
G
G
A
G
G
C
A
G
C
C
T
G
T
G
G
A
G
G
A
A
C
T
G
G
G
T
A
G
2000
G
A
T
T
T
A
G
G
A
A
C
G
C
A
C
C
G
T
G
C
A
C
A
T
G
C
T
T
G
G
T
G
G
T
C
T
T
G
T
T
A
A
G
T
G
G
A
A
A
C
2050
T
G
C
T
G
C
T
T
T
A
G
A
G
T
T
T
G
T
T
T
G
G
A
A
G
G
T
C
C
G
G
G
T
G
A
C
T
C
A
T
C
C
C
A
A
C
A
T
T
T
2100
A
C
A
T
C
C
T
T
A
A
T
T
G
T
T
A
A
A
G
C
G
C
T
G
C
C
T
C
C
G
A
G
C
G
C
A
C
G
C
A
T
C
C
T
G
A
G
A
T
C
2150
C
T
G
A
G
C
C
T
T
T
G
G
T
T
A
A
G
A
C
C
G
A
G
C
T
C
T
A
T
T
A
A
G
C
T
G
A
GTG AGTAAATTGT
2200
AAAACCAGTT TCGCTGAGAG TGTGTGTCTG GAAAGGTTGG TGGGCGTTGT
2250
GTATATATTT GTTAGAAAAT CGGTAACCGT TCAAACGAGA CGACTGAGTT
2300
TTTTAGCCTT TCGCAGTTTC ATTTGAAAGT GGGTATGC
A
G TTTAAAACTG
2350 |
var(2339):[G:0.28]
ACAGTTCAAA GTGGTTTTTC AGAAAATGAT GCCCTGGTGC AAACTGATTC
2400
TGGGTCCCAT AGTGTGTTAA GTGTGGGTTG GTAAAAACTC TTGGCCTTTC
2450
TCCAAATG
T
A TGAAATTAAA GTTGATATTG GAAGGATAAA AACCCACTGA
2500 |
var(2459):[C:0.01]
GCACAGAAGT TACTATAGGT GGAGGAAACA TTTGTTGATG TTAATATTTT
2550
AAAGGGGTTG ACCAATATAG GAATTGGTCA ATGACAATTG GGAATAGGTA
2600
AATGACAAAT TATTGGTCAA TCCCTTTAAA GCTTTGGATG GTTTGCTAAA
2650
GAATTATTGA ACTCCCTTTT GTAATTTTCT GTGGATAGTT GAGTGCTCTT
2700
ACTCCCTTCT CAGTCCTAGA GATATCCCCT AAAGCTTGGT TTTTAGGAGG
2750
ATCTTACAGC TCTCTTATCA TTTGAATGTC AGCTAGTCAT AAATAAATAC
2800
G
CCAGAGTAG TAAGGAAGAG ATGTTTTTTA TTGATATTCT TTACAAAACA
2850 |
var(2801):[A:0.16]
GTGCTTTCAG AGTA
C
AGCTT TGACTGGATT GTATAGATCT TGATGAGATC
2900 |
var(2865):[A:0.01]
TTGATGAGAA AGGTTTCAAC GACAAAGATG GCATGTTAAG TCTAACATTA
2950
CCCTTCCATT ATAAACATTG AAAGATGTTG GTTATTTTAT TATTTA
T
T
T
T
3000 |
REPEAT
A
T
A
A
T
A
A
C
T
T
T
T
A
A
T
T
G
T
G
A
A
A
T
A
A
T
T
T
G
A
G
A
G
T
T
A
C
T
G
A
A
A
A
T
T
T
G
C
A
A
3050
A
A
A
A
T
A
G
T
A
C
A
G
A
G
A
G
T
T
C
C
C
A
T
A
A
T
A
T
C
A
T
G
C
A
T
A
A
C
A
A
G
G
G
C
C
A
A
A
A
C
3100 |
NOT SCANNED
T
A
A
T
A
A
C
A
T
G
G
G
C
A
T
G
C
T
A
C
T
A
T
A
A
T
A
C
A
A
T
G
A
A
C
T
A
A
A
C
T
A
C
A
G
A
C
T
T
T
3150
A
T
T
T
G
G
A
T
T
T
C
A
C
T
T
G
T
C
T
T
T
C
C
A
C
T
G
T
C
C
T
T
T
T
T
C
T
G
C
C
C
A
G
G
A
T
C
C
A
A
3200
T
C
G
A
T
G
A
T
C
T
C
A
C
T
T
T
G
C
A
T
T
T
A
A
C
T
G
C
T
A
A
A
T
A
T
C
C
T
T
A
A
T
T
T
T
C
T
C
T
G
3250
A
T
C
T
G
T
G
A
C
A
G
T
T
C
C
T
C
A
G
C
C
T
T
T
C
A
T
T
G
T
T
T
T
T
T
C
A
T
G
G
A
C
C
T
T
G
A
C
A
C
3300
T
A
G
T
G
A
A
G
A
A
G
A
C
C
C
G
G
T
C
A
G
T
T
A
A
T
T
T
G
T
A
G
A
A
T
G
C
C
C
C
T
C
A
A
T
T
T
G
T
G
3350
T
T
T
G
C
T
T
G
A
T
G
T
T
T
A
G
T
G
T
C
A
T
G
A
T
T
A
G
A
T
G
A
A
T
G
T
T
C
T
G
C
A
T
T
T
T
G
G
G
G
3400
A
A
A
A
A
T
G
T
C
A
C
A
G
A
A
G
T
A
A
A
G
T
T
T
C
C
A
T
C
T
C
A
G
T
A
T
G
T
C
A
T
A
T
T
G
G
G
T
A
C
3450
A
T
G
A
T
G
T
C
A
A
T
A
C
T
T
T
T
T
T
T
T
G
A
G
A
C
T
G
A
G
T
C
T
T
G
C
T
T
T
A
T
T
G
C
C
C
A
G
A
C
3500 |
REPEAT
T
G
G
A
G
T
G
C
A
G
T
G
G
C
A
C
G
A
T
C
T
C
A
G
C
T
C
A
T
T
G
C
A
A
C
C
T
T
T
G
C
C
T
C
C
C
A
G
G
T
3550
T
C
T
A
G
C
G
A
T
T
C
T
C
C
T
G
C
C
T
C
A
G
C
C
T
C
C
T
G
A
G
T
A
G
C
T
G
G
G
A
T
T
A
T
A
G
G
C
G
C
3600
C
T
G
C
C
A
C
C
A
T
G
C
C
C
A
G
A
T
A
A
T
T
T
T
T
T
G
T
A
T
T
T
T
T
A
G
T
A
G
A
G
A
C
A
G
G
T
T
T
C
3650
A
T
G
T
T
G
G
C
C
A
G
G
C
T
G
G
T
C
T
C
G
A
A
C
T
C
C
T
G
A
C
C
T
C
T
A
G
T
G
A
T
C
C
T
C
C
T
G
C
C
3700
T
T
G
G
C
C
T
C
C
C
A
A
A
G
T
G
C
T
G
G
G
A
T
T
A
C
A
G
G
C
G
T
G
A
G
C
C
A
C
T
G
T
G
C
C
C
T
A
G
C
3750 |
REPEAT
C
G
A
T
A
C
T
T
C
T
T
A
T
T
A
C
C
T
A
T
G
A
T
G
T
T
A
A
T
C
T
G
T
T
T
G
C
C
A
G
A
T
T
C
C
C
T
T
T
G
3800
T
A
T
T
T
G
A
G
A
T
C
T
T
G
G
G
A
G
A
G
A
A
A
C
C
T
G
C
A
C
T
G
C
C
A
T
T
T
T
T
C
C
T
T
A
A
A
C
T
T
3850
T
T
A
T
T
C
A
T
T
A
A
T
T
T
A
A
G
C
A
T
C
C
A
T
T
T
G
T
G
G
A
A
C
A
T
G
T
T
G
T
T
T
A
G
C
G
G
G
T
T
3900
T
T
T
T
T
T
C
C
T
A
A
T
G
G
T
T
A
A
A
C
A
A
A
A
C
C
C
C
T
A
T
T
T
T
C
T
T
C
C
T
T
C
T
A
C
A
T
T
T
T
3950
T
T
A
A
T
T
A
A
A
A
T
T
C
C
C
T
T
C
T
G
T
A
G
G
G
A
A
G
A
G
T
T
G
A
C
C
C
T
T
C
T
C
T
C
C
T
G
T
T
C
4000
A
T
T
G
A
T
T
C
A
G
T
T
A
T
T
T
G
T
A
T
C
A
G
T
A
T
G
G
G
C
T
C
A
T
G
G
A
T
A
T
T
T
G
T
T
T
T
G
T
T
4050
A
T
A
T
G
G
G
T
T
A
T
A
A
T
C
C
A
A
T
A
T
T
A
T
C
A
G
T
A
T
T
T
A
A
T
T
T
G
C
T
G
C
T
C
A
A
A
T
T
G
4100
T
T
C
T
G
G
C
T
T
T
C
A
C
C
A
C
T
G
G
G
A
C
C
T
T
T
T
T
C
A
G
G
T
T
G
G
C
G
C
C
T
G
T
G
C
C
A
C
T
T
4150
T
G
A
C
A
T
A
C
A
C
T
T
G
C
T
T
T
T
T
C
T
T
T
T
T
C
C
T
T
C
T
T
T
T
T
T
T
T
T
T
T
T
T
T
T
T
T
T
T
T
4200 |
REPEAT
T
T
G
A
G
A
C
G
G
A
G
T
C
T
T
T
G
T
C
G
C
C
C
A
G
G
C
T
G
G
A
G
T
G
C
A
G
T
G
G
C
A
C
G
A
T
C
T
C
G
4250
G
C
T
C
A
C
T
G
C
A
C
C
C
T
C
C
G
C
C
T
C
C
C
A
G
G
C
T
C
A
A
G
C
G
A
T
T
C
T
T
G
T
G
C
C
T
C
A
G
C
4300
C
T
A
C
C
A
A
G
T
A
G
C
T
G
G
G
A
T
T
A
C
A
G
G
T
A
C
G
T
A
G
C
A
C
C
A
C
A
C
T
T
G
G
C
T
A
C
T
T
T
4350
T
T
G
T
A
T
T
T
T
T
T
A
G
T
A
G
A
G
A
C
G
G
G
G
T
T
T
T
C
C
A
T
G
T
T
G
G
C
C
A
G
G
C
T
G
G
T
C
T
C
4400
A
A
A
C
T
C
C
T
G
G
C
C
T
C
A
A
G
T
G
A
T
C
T
G
C
C
C
G
C
C
T
C
G
G
C
C
T
C
C
C
A
A
A
G
T
G
C
T
G
G
4450
G
A
T
T
A
C
A
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G
T
G
T
G
A
G
C
T
A
T
C
A
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C
C
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G
A
C
T
C
T
T
T
T
T
C
T
T
T
T
T
T
A
A
T
G
C
A
4500 |
REPEAT
T
T
T
C
T
T
G
A
T
T
T
C
T
G
G
C
A
T
C
A
G
A
G
A
A
T
G
C
T
C
A
G
G
C
T
T
A
T
T
T
T
G
T
A
T
T
T
T
C
C
4550
A
T
G
T
C
C
C
A
A
C
C
T
T
G
G
A
A
T
G
A
T
C
C
A
T
T
T
C
T
C
C
A
A
G
G
C
A
C
T
G
T
G
A
T
T
A
T
T
T
T
4600
G
C
T
T
T
A
G
A
A
T
G
G
T
A
T
T
A
G
A
A
G
C
T
A
A
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A
T
C
T
G
G
A
C
A
C
T
G
G
A
T
G
T
T
C
T
A
T
T
A
4650
G
A
G
T
T
A
C
T
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C
T
T
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A
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A
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A
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T
C
T
T
G
C
T
C
C
A
G
G
C
C
A
G
A
G
T
G
4700 |
REPEAT
C
A
A
T
G
G
T
G
G
G
A
T
C
T
C
A
G
C
T
G
A
C
T
G
C
A
A
C
C
T
C
C
T
C
C
G
C
T
T
C
C
T
G
G
G
T
T
C
A
A
4750
G
C
A
A
T
T
C
T
C
C
T
G
C
C
T
C
A
G
C
C
T
C
C
T
G
A
G
T
A
G
C
A
G
G
G
A
T
T
A
C
A
G
G
C
A
T
G
T
G
C
4800
C
A
C
C
A
C
G
C
C
C
A
G
C
T
A
A
T
T
T
T
T
A
A
T
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T
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T
T
T
A
G
T
A
A
A
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A
C
G
A
G
G
T
T
T
T
G
C
C
4850
A
T
G
T
T
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G
C
C
A
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C
T
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G
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C
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A
A
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T
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C
T
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A
C
T
T
T
G
G
G
T
G
A
T
C
C
A
C
C
C
G
C
C
4900
T
C
G
G
C
C
T
C
C
C
C
A
A
G
T
G
C
T
G
G
G
A
A
T
A
C
A
G
G
C
A
T
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A
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C
C
A
C
C
G
T
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C
C
C
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G
C
C
4950
T
A
G
A
G
T
T
A
C
T
T
T
T
G
A
A
C
T
T
T
T
T
A
T
G
T
A
T
A
A
T
A
A
A
A
A
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T
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T
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A
C
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A
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C
5000
A
A
A
T
G
C
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A
A
G
T
C
T
G
A
A
A
A
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A
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T
G
G
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A
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G
C
C
T
C
T
G
A
G
C
C
C
A
A
G
C
T
A
A
G
5050 |
REPEAT
C
C
A
T
C
A
T
A
T
C
C
T
C
T
G
T
G
A
C
C
T
A
C
A
C
T
T
A
C
A
C
A
T
C
C
A
G
A
T
G
G
C
T
G
G
T
T
C
C
T
5100
G
C
C
T
T
A
A
C
T
G
A
T
G
A
C
A
T
T
A
C
C
T
T
G
T
G
A
A
A
T
T
C
C
T
C
C
T
T
C
T
G
G
C
T
C
A
T
C
C
T
5150
G
G
C
T
C
T
G
T
A
C
T
G
C
C
T
C
A
A
G
G
C
T
T
C
A
C
A
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A
C
A
G
C
C
C
C
C
A
T
T
A
C
T
T
C
A
G
T
C
A
5200 |
REPEAT
A
A
C
C
C
A
A
A
T
T
T
C
T
T
C
C
T
C
A
T
C
T
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C
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A
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A
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A
A
T
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T
T
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A
T
A
5250
A
A
A
A
C
A
C
A
C
G
T
G
C
T
C
T
C
C
C
T
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C
C
A
A
T
C
G
T
G
T
C
T
G
A
C
T
G
A
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C
T
C
T
C
A
A
A
C
C
5300
C
C
A
A
C
A
C
C
T
T
C
T
A
C
A
A
A
A
C
A
A
C
T
C
C
T
T
T
C
C
T
T
C
C
T
A
G
G
C
A
T
G
G
T
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G
A
T
A
5350
C
T
T
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C
G
A
C
T
T
T
G
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A
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A
C
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A
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5400
A
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5450
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5500
T
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5550
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5600
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5650
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5700
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5750
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5800
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5850
G
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5900
C
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5950
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6000
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6050
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6100
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6150
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6200
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6250
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6300
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6350
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6400
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6450
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6500
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6550
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6600
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6650
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6700
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6750
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6800
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6900
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6950
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T
T
T
C
G
G
G
C
T
C
T
T
7000
G
G
T
A
T
T
C
A
G
T
G
A
A
A
C
A
T
T
T
A
T
A
T
C
C
C
T
T
A
C
C
A
T
C
C
T
C
A
A
T
C
T
T
C
A
G
G
A
A
A
7050
G
G
T
A
G
A
A
C
G
G
A
C
T
A
C
T
G
G
T
C
T
T
T
T
A
A
A
A
A
C
A
C
A
C
C
T
C
A
C
C
A
A
G
C
T
C
A
G
C
C
7100
A
C
C
A
A
C
T
T
A
A
A
A
A
G
G
A
C
T
G
G
A
T
A
A
T
A
C
T
T
T
T
A
C
C
A
C
T
T
G
C
C
C
T
T
C
T
C
A
G
A
7150
A
T
T
C
G
G
G
C
C
T
G
T
C
T
T
C
G
G
A
A
T
G
C
G
A
C
A
A
A
A
T
A
C
A
G
C
C
C
A
T
T
T
G
A
G
C
T
C
C
T
7200
G
T
A
T
A
G
A
T
G
C
T
C
C
T
T
T
T
T
A
T
T
A
G
G
C
C
C
C
A
G
T
C
T
C
A
T
T
C
C
A
G
A
C
A
C
C
A
G
A
C
7250
C
A
A
C
T
T
G
G
A
C
T
G
C
G
C
C
C
C
C
A
A
A
A
A
C
T
T
G
T
C
A
T
C
C
C
T
A
C
T
A
T
C
T
T
C
T
G
T
C
T
7300 |
REPEAT
A
G
T
C
A
T
A
C
T
C
C
T
A
T
T
C
A
C
C
A
T
T
C
T
C
A
A
C
T
A
C
T
C
A
T
A
C
A
T
G
C
C
C
G
C
T
C
T
T
G
7350
T
T
T
A
C
A
C
T
G
C
C
G
G
T
T
T
A
C
A
C
T
G
T
T
T
C
T
C
C
A
A
G
C
C
A
C
C
A
C
A
G
C
T
G
A
T
A
T
C
T
7400
C
C
T
G
G
T
G
C
T
A
T
C
C
C
C
A
A
A
C
C
G
C
C
A
C
T
C
T
C
A
A
C
T
C
T
T
A
A
A
G
T
A
A
A
T
A
A
A
T
C
7450
A
T
C
T
T
T
G
C
T
G
G
C
A
G
G
G
C
T
A
T
G
C
T
G
A
A
C
C
T
C
C
T
T
A
G
G
C
A
C
T
C
T
C
T
A
A
T
T
G
G
7500 |
REPEAT
A
T
G
T
C
C
T
G
G
G
T
C
C
T
C
C
C
A
A
T
T
C
T
T
A
G
T
C
C
T
T
T
A
A
T
A
C
C
T
G
T
T
T
T
T
C
T
C
C
T
7550
T
G
T
C
T
T
A
T
T
C
C
G
T
T
C
T
T
T
T
T
T
C
A
A
T
T
C
A
T
A
C
A
A
A
A
T
T
G
T
A
T
C
C
A
G
G
C
C
A
T
7600
C
A
C
C
A
A
T
A
C
T
T
A
T
A
T
A
G
G
A
C
A
A
T
T
G
T
T
T
C
T
T
C
T
A
A
C
A
A
C
C
C
C
A
C
A
A
T
A
T
C
7650
A
C
C
C
C
T
T
A
C
C
A
C
A
A
A
A
T
C
T
T
C
C
T
T
C
A
G
C
T
T
A
A
T
C
T
C
T
C
C
C
A
C
T
T
T
A
G
G
T
T
7700
C
C
C
A
C
G
C
C
G
C
C
C
C
T
A
A
T
C
C
C
A
C
T
T
G
A
A
G
C
A
G
C
C
C
T
G
A
G
A
A
A
C
A
T
C
A
C
C
C
A
7750
T
T
C
T
C
T
C
T
C
C
A
T
A
C
C
A
C
C
C
C
C
C
A
A
A
A
A
T
T
T
T
C
A
C
C
A
C
C
C
C
A
A
C
A
C
T
T
T
A
C
7800
C
A
C
T
A
T
T
T
T
G
T
T
T
T
A
T
T
T
T
T
C
T
T
A
T
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A
A
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A
T
A
A
G
A
A
G
A
C
A
G
G
A
A
T
G
T
C
A
G
7850 |
REPEAT
G
C
C
T
C
T
G
A
G
C
C
C
A
A
G
C
T
A
A
G
C
C
A
T
C
A
T
A
T
C
C
C
C
T
G
T
G
A
C
C
T
G
C
A
C
A
T
A
T
A
7900
C
A
T
C
C
A
G
A
T
G
G
T
T
G
G
T
T
C
C
T
G
C
C
T
T
A
A
C
T
G
A
T
G
A
C
A
T
T
C
C
A
C
C
A
C
A
A
A
A
G
7950
A
A
C
T
G
A
A
A
A
T
G
G
C
C
T
G
T
T
C
C
T
G
C
C
T
T
A
A
C
T
G
A
T
G
A
C
A
T
T
A
C
C
T
T
G
T
G
A
A
A
8000
T
T
C
C
T
T
C
T
C
C
T
G
G
C
T
C
A
T
T
C
T
G
G
C
T
C
A
A
A
A
G
C
T
C
C
C
C
C
G
C
T
G
A
G
C
A
C
C
C
T
8050
G
T
G
A
C
G
C
C
C
C
A
C
C
C
C
T
G
C
C
C
A
C
C
A
G
A
G
A
A
C
A
A
A
C
C
C
C
C
T
T
T
A
C
C
C
T
T
T
A
C
8100
C
T
A
C
C
C
A
A
A
T
C
T
T
A
T
G
A
A
A
T
G
G
C
C
C
C
A
T
C
C
C
T
A
T
C
T
C
C
C
T
T
T
G
C
T
G
A
C
T
T
8150
T
C
T
T
T
T
C
G
G
A
C
T
C
A
G
C
C
C
G
C
C
T
G
C
A
T
C
C
A
G
G
T
G
A
T
T
A
A
A
A
A
G
C
T
T
T
A
T
T
G
8200
C
T
C
A
C
A
C
G
A
A
G
C
C
T
G
T
T
T
G
G
T
G
G
T
C
T
C
T
T
C
A
C
A
C
G
G
A
C
G
C
G
A
G
T
G
A
A
A
A
T
8250
T
C
A
T
A
T
T
G
C
C
T
T
A
A
A
G
T
T
T
A
A
A
C
A
T
T
A
T
A
G
A
G
G
A
C
C
T
G
A
C
T
G
T
A
T
T
T
G
C
C
8300
A
A
C
T
T
G
G
A
T
T
C
A
G
T
C
T
C
T
T
A
T
G
G
G
A
A
A
G
A
A
G
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A
A
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A
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G
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A
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A
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8350
T
A
A
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T
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A
A
A
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C
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C
C
C
A
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T
T
T
T
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T
C
T
C
A
A
A
T
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A
A
A
C
C
C
T
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C
C
A
G
T
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C
T
8400
T
C
C
A
A
A
A
C
A
A
A
T
A
A
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C
A
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A
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T
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C
T
A
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C
T
A
T
T
A
G
G
C
T
C
T
G
G
T
A
A
8450
G
A
A
A
C
C
A
G
G
A
T
C
A
T
T
T
T
A
T
T
A
G
C
T
G
A
G
T
A
G
C
T
T
A
A
A
C
T
A
C
A
T
C
C
T
A
A
T
A
T
8500
T
A
T
A
A
T
T
T
T
G
G
T
A
T
C
T
G
T
T
G
A
T
T
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A
A
T
T
C
A
C
A
G
T
G
A
G
A
A
A
A
G
G
A
T
T
T
G
A
G
8550
A
C
C
C
A
T
A
T
T
T
A
T
G
T
T
A
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T
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A
T
A
C
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C
A
A
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A
A
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A
A
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A
C
T
G
T
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T
T
T
A
T
G
8600
A
T
G
A
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A
C
A
T
T
A
T
T
T
G
G
T
C
T
G
A
G
A
T
G
G
T
A
A
C
T
G
T
A
C
C
C
G
T
G
G
A
T
T
A
G
A
G
A
G
8650
A
G
G
A
T
C
C
C
T
T
G
C
A
A
T
A
A
T
T
A
A
T
G
A
G
C
C
C
T
T
C
T
A
T
G
A
T
T
T
T
G
G
A
G
T
A
C
A
C
A
8700
C
A
C
A
T
T
A
C
A
T
G
C
T
C
C
T
T
C
T
T
T
T
A
T
A
T
C
T
T
T
G
T
A
T
A
C
T
G
G
A
T
C
A
T
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A
T
G
T
T
8750
T
T
T
T
A
T
T
G
T
A
G
G
T
C
T
C
A
G
A
A
T
T
T
T
G
A
G
A
A
G
T
A
A
T
G
C
C
G
C
T
G
C
T
C
A
C
A
T
T
T
8800
A
A
T
T
T
T
C
T
G
T
T
A
A
T
A
A
T
T
C
T
T
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T
T
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T
T
T
T
T
T
T
T
G
A
G
A
T
G
G
A
G
T
C
T
C
A
C
T
8850 |
REPEAT
C
T
G
T
C
G
C
C
C
A
G
G
C
T
G
G
A
G
T
G
C
A
G
T
G
G
C
G
C
C
A
T
C
T
C
G
G
C
T
C
A
C
T
G
C
A
A
G
C
T
8900
C
C
A
C
C
T
C
C
C
G
G
G
T
T
C
A
C
G
C
C
A
T
T
C
T
C
C
T
G
C
C
T
C
A
G
C
C
T
C
C
C
C
A
G
C
A
G
C
T
G
8950
G
G
A
C
T
A
C
C
G
G
C
G
C
C
C
C
T
C
C
A
C
C
A
C
G
C
C
C
A
G
C
T
A
C
T
T
T
T
T
T
G
T
A
T
T
T
T
T
A
G
9000
T
A
G
A
G
A
T
G
G
G
G
T
T
T
C
A
C
C
G
T
G
T
T
A
G
C
C
A
G
G
A
T
G
G
T
C
T
T
G
A
T
C
T
C
C
T
G
A
C
C
9050
T
C
G
T
G
A
T
C
C
A
C
C
T
G
C
C
T
C
G
G
C
C
T
C
C
C
A
A
A
G
T
G
C
T
G
G
G
A
T
T
A
C
A
G
G
C
A
T
G
A
9100
G
C
C
A
C
T
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C
A
C
C
C
A
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C
C
T
C
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C
A
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A
A
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T
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T
A
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T
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C
A
A
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C
G
A
T
G
A
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T
9150
G
A
A
T
T
A
T
A
A
A
C
T
G
G
A
A
G
G
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A
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A
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A
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T
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C
A
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A
G
T
T
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A
C
A
9200
T
G
T
A
C
T
A
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A
C
T
C
A
C
G
G
A
G
A
A
C
A
A
G
G
A
C
T
G
G
G
T
T
G
T
A
G
G
C
A
C
A
A
T
G
C
T
G
T
G
9250
T
G
G
T
T
T
T
G
G
G
T
A
A
A
T
C
T
A
A
C
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A
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A
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C
C
C
C
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9300
G
G
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A
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T
T
A
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G
A
T
C
C
C
A
A
A
A
T
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9350
C
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A
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C
C
A
A
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T
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G
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A
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A
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C
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T
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C
A
A
A
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G
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A
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A
A
G
A
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A
9400
A
A
G
G
G
T
G
A
T
G
A
C
T
T
T
C
C
C
A
G
A
G
C
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T
C
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C
C
G
C
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T
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C
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C
C
C
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A
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T
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C
9450
T
A
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C
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C
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A
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A
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G
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C
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A
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9500
A
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C
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A
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C
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A
A
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9550
T
G
A
A
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C
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C
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A
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A
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A
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T
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C
C
A
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T
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A
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9600
A
A
G
A
G
G
A
G
G
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A
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G
A
A
A
T
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G
A
A
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T
T
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G
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C
A
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G
C
G
A
T
T
T
T
G
C
A
G
A
A
C
9650
A
T
G
C
A
C
A
G
A
T
A
A
T
A
G
G
T
T
T
C
A
G
G
G
A
G
C
T
C
T
C
A
T
A
G
G
C
T
A
T
G
G
A
G
G
G
A
G
G
G
9700 |
REPEAT
G
T
G
C
A
G
G
A
C
A
G
T
G
T
C
C
T
C
A
T
C
T
T
G
G
C
T
C
T
T
G
A
T
A
T
T
A
T
T
A
T
G
G
T
G
G
A
C
T
C
9750
T
T
A
T
G
T
G
G
T
C
T
C
C
C
T
G
C
A
T
T
G
T
C
C
C
T
A
C
C
C
A
T
G
A
C
C
A
A
A
G
T
C
A
G
A
G
T
G
A
T
9800
C
C
T
T
T
A
A
A
C
C
A
A
G
C
T
T
G
T
C
C
A
A
C
G
T
G
C
A
T
G
T
G
G
C
C
C
A
A
G
A
T
G
G
C
T
T
T
G
A
A
9850 |
REPEAT
T
G
A
A
G
C
C
C
A
A
C
A
C
A
A
A
T
T
A
G
T
A
A
A
C
T
T
T
C
T
T
A
A
A
A
C
A
T
T
A
T
G
T
G
A
T
T
T
T
T
9900
G
T
T
T
T
T
A
A
T
T
T
A
G
C
T
C
A
T
C
A
G
C
T
G
T
T
G
T
T
A
A
T
G
T
T
A
G
T
G
T
G
T
T
T
T
A
T
A
T
G
9950
T
G
G
C
C
C
A
A
G
A
C
A
A
T
T
C
T
T
C
T
T
C
C
A
G
T
G
T
G
G
C
C
C
A
G
G
G
A
A
G
C
C
A
A
A
A
G
A
T
T
10000
G
G
A
C
A
C
T
C
C
T
G
C
T
T
T
A
A
A
T
A
T
A
G
A
T
A
T
C
A
T
T
T
C
T
T
C
A
C
T
C
A
G
A
A
C
T
T
T
C
C
10050 |
REPEAT
T
G
T
G
C
C
T
T
C
C
A
G
T
G
C
C
A
T
T
C
A
G
A
T
C
A
A
A
G
C
C
A
A
A
G
T
C
C
T
T
C
C
T
G
T
G
G
T
C
A
10100
G
T
G
G
T
A
G
A
T
A
C
A
A
C
C
C
G
A
G
T
T
C
C
T
G
C
T
C
T
C
T
T
A
T
C
C
T
C
C
C
T
C
A
C
T
C
T
G
C
T
10150
T
C
A
G
C
C
T
C
A
C
T
G
G
C
C
T
C
T
T
T
G
C
T
G
T
T
C
C
T
T
C
G
A
C
C
A
G
C
A
C
T
T
G
G
A
C
A
T
A
T
10200
A
C
T
G
C
T
C
C
T
C
C
A
G
A
A
G
G
C
C
A
C
C
C
T
C
A
G
A
G
C
T
C
T
G
C
T
T
G
A
G
G
G
C
C
T
C
A
C
T
G
10250
G
A
A
A
G
G
C
C
T
T
C
C
G
T
G
A
C
C
A
C
C
T
C
T
G
T
T
G
C
C
C
A
G
G
T
T
G
G
A
G
T
G
C
A
T
T
G
G
T
G
10300 |
REPEAT
T
G
A
C
C
T
T
G
G
C
T
C
A
C
T
G
C
A
A
T
C
T
C
T
G
C
C
T
C
C
C
G
G
G
T
T
C
A
A
G
C
A
A
T
T
C
T
T
G
T
10350
G
C
C
T
C
A
G
T
C
T
C
C
C
A
A
G
T
A
G
C
A
G
G
A
A
T
T
A
C
A
G
G
T
A
T
G
C
G
C
C
A
C
C
A
C
A
C
C
C
G
10400
G
A
T
A
A
T
T
T
T
T
G
T
A
T
G
T
T
T
A
A
T
A
G
A
G
A
T
A
A
G
G
A
T
T
T
C
A
C
C
A
T
A
T
T
G
T
C
C
A
G
10450
G
C
T
G
G
T
C
T
C
C
A
A
A
T
T
C
C
G
G
G
C
C
T
C
A
A
G
C
A
A
T
C
C
A
C
C
C
A
C
C
T
C
G
G
C
C
T
C
C
C
10500
A
A
A
G
T
G
C
T
G
G
G
A
T
T
A
C
A
G
G
C
G
T
G
A
G
C
C
A
C
C
A
T
T
T
C
T
G
G
C
C
C
A
C
C
C
T
T
C
C
T
10550
C
T
T
T
T
G
C
T
T
T
A
A
T
T
T
T
T
T
T
T
C
T
C
C
G
T
A
G
C
A
C
T
G
T
T
G
A
C
T
G
A
T
A
T
T
T
T
T
C
A
10600
T
A
T
G
T
A
A
C
C
T
C
A
C
T
G
A
G
G
G
C
C
G
G
G
A
T
G
T
T
T
A
T
C
T
G
T
T
G
T
T
T
T
G
T
T
T
T
G
T
T
10650 |
REPEAT
C
A
C
T
C
C
T
G
T
A
A
G
T
C
C
A
G
T
G
C
C
T
G
C
C
A
G
A
T
A
A
T
A
G
A
A
G
T
C
T
A
G
T
A
A
A
T
A
T
C
10700
G
A
A
T
T
A
T
T
A
T
T
A
T
T
A
T
T
T
T
T
T
G
A
G
A
C
A
G
A
G
T
T
T
C
G
C
T
C
T
T
G
T
T
G
C
C
C
A
G
A
10750 |
REPEAT
A
T
G
G
A
G
T
G
C
A
A
T
G
G
T
G
C
G
A
G
C
T
C
A
G
C
T
C
A
C
C
G
C
A
A
C
C
T
C
T
G
C
C
T
C
C
C
A
G
G
10800
T
T
C
A
A
G
C
A
G
T
T
C
T
C
C
T
G
C
C
T
C
A
G
C
C
T
C
C
C
G
A
G
T
G
G
C
T
G
G
G
G
T
T
A
C
A
G
G
C
A
10850
T
G
C
G
C
T
A
C
C
A
T
G
C
C
C
A
A
C
T
A
A
T
T
T
T
G
T
A
T
T
T
T
T
A
G
T
A
G
A
G
A
C
A
G
G
G
T
T
T
C
10900
T
C
C
A
T
G
T
T
G
G
T
C
A
G
G
C
T
G
G
T
C
T
C
G
A
A
C
T
C
C
C
G
A
C
C
T
C
A
T
G
T
G
A
T
C
C
G
C
C
T
10950
G
C
C
T
C
G
G
C
C
T
C
C
C
A
A
A
G
T
G
C
T
G
G
C
A
T
T
A
C
A
G
G
C
A
T
G
A
A
C
C
A
C
C
A
T
G
C
C
C
G
11000
G
C
C
G
A
A
T
T
A
A
T
T
T
T
A
T
A
G
G
T
G
A
G
A
A
A
C
A
G
G
C
T
T
G
G
A
G
A
G
G
C
T
A
A
G
C
A
G
T
T
11050 |
REPEAT
T
C
T
C
C
A
G
G
G
T
T
C
T
G
T
G
G
C
T
A
G
G
A
A
G
T
T
T
A
A
G
G
G
G
A
G
A
A
G
G
A
G
C
T
G
A
A
A
C
C
11100
C
C
A
C
A
C
A
T
T
C
T
G
T
G
A
T
G
G
A
T
T
G
G
A
T
A
G
C
A
T
T
T
T
A
T
G
G
G
C
A
G
C
C
T
T
A
G
G
A
T
11150
T
T
G
A
A
C
A
T
C
T
C
C
G
T
T
C
C
C
T
C
T
G
G
G
A
A
A
C
T
G
C
T
G
G
C
C
A
A
A
T
T
G
C
A
G
A
T
T
A
G
11200
A
T
T
A
A
G
A
A
A
A
T
T
T
G
G
G
A
T
G
T
A
A
C
A
C
G
C
A
T
G
T
A
A
A
T
T
G
C
A
C
T
T
G
G
T
C
T
A
A
T
11250
T
T
C
A
T
T
T
A
T
G
A
T
T
T
G
A
C
G
A
T
T
T
T
C
T
A
G
A
C
T
G
A
A
G
T
T
T
T
G
G
C
T
T
T
C
T
A
A
T
C
11300
A
C
A
G
A
T
T
A
A
A
A
C
C
A
A
T
T
T
G
G
A
C
A
G
A
A
T
T
C
T
T
T
T
A
T
T
T
A
T
T
T
A
T
T
T
A
T
T
T
T
11350 |
REPEAT
T
A
T
A
T
T
T
T
A
G
A
G
A
A
A
G
G
A
T
C
T
T
G
C
T
C
T
C
A
C
C
C
A
G
A
C
G
G
G
A
G
T
A
T
A
G
T
G
G
C
11400
G
T
G
A
T
C
T
T
G
A
C
T
C
A
C
T
G
C
A
G
C
C
T
G
G
A
A
C
T
C
C
C
T
G
G
G
C
T
C
A
A
G
G
G
A
T
C
C
C
C
11450
C
T
T
C
C
T
C
A
G
C
C
T
C
A
C
A
A
G
T
A
G
C
T
A
G
G
T
C
T
A
C
A
G
G
C
A
T
G
T
G
C
C
A
C
C
A
C
A
C
C
11500
C
G
G
C
T
A
A
T
T
T
T
T
C
A
A
T
T
T
T
A
T
T
T
T
T
T
G
T
A
C
A
G
A
C
G
A
G
C
A
G
A
A
T
T
C
C
T
G
C
A
11550
G
A
T
T
T
T
T
G
T
G
G
G
A
A
T
G
T
A
A
A
T
G
A
A
A
A
A
A
C
A
G
T
A
G
C
C
T
T
G
T
A
G
G
G
T
C
T
T
A
T
11600
G
T
T
C
A
T
T
T
G
T
T
T
C
T
A
T
T
C
A
A
A
G
A
G
A
G
G
A
T
T
T
A
G
A
T
T
A
A
G
C
T
G
A
A
A
A
A
T
T
A
11650
A
G
G
G
G
A
C
A
G
A
A
A
A
C
T
G
A
T
T
A
G
T
G
G
T
T
G
T
C
A
G
G
G
G
C
T
C
T
G
G
T
A
A
G
G
A
G
A
G
G
11700 |
REPEAT
G
G
A
T
T
T
C
T
T
T
G
G
G
T
T
A
A
C
A
T
G
A
A
T
G
A
T
C
T
G
T
C
T
T
G
A
T
T
G
T
A
G
T
G
G
T
T
A
C
A
11750
G
G
A
C
T
G
T
G
T
A
C
A
C
T
T
T
A
C
A
A
T
G
T
C
A
G
A
A
A
A
C
T
G
T
G
C
T
C
T
T
A
A
A
A
A
G
G
A
T
G
11800
A
A
T
T
T
T
A
C
T
G
T
T
T
A
C
A
A
T
A
C
T
G
T
T
T
C
C
T
G
T
T
G
A
C
G
G
G
T
T
T
C
C
A
A
T
A
A
A
C
A
11850
T
G
A
T
T
A
A
A
A
A
A
A
C
C
A
A
A
G
A
T
T
A
G
G
C
A
G
A
A
C
C
G
T
G
T
G
T
A
C
A
G
T
T
G
G
C
A
T
A
G
11900
G
A
T
C
C
C
T
T
C
C
A
A
A
A
C
A
G
T
T
T
T
T
C
C
T
T
A
G
T
A
A
T
A
A
G
T
A
T
T
A
A
T
T
T
C
T
G
T
A
A
11950
G
T
T
A
T
T
A
A
T
T
T
C
C
T
A
T
A
G
A
T
A
C
C
T
T
G
C
T
G
G
C
T
T
T
A
C
T
G
A
A
A
A
T
C
T
T
G
T
A
G
12000
G
A
T
C
A
G
G
A
T
A
T
A
T
A
G
G
A
G
T
G
A
G
G
A
G
A
G
G
G
T
A
G
A
G
C
T
G
G
G
A
C
C
T
T
G
C
A
G
T
C
12050
A
G
G
G
A
C
C
C
T
C
C
A
G
A
A
T
T
C
C
A
G
G
G
T
C
A
A
G
T
C
T
T
A
G
C
T
C
C
T
G
A
T
C
A
G
G
C
A
C
G
12100
C
T
G
C
A
C
C
C
T
T
T
T
G
A
T
G
G
T
C
T
T
T
G
C
T
T
A
C
C
T
T
T
T
T
A
G
C
C
T
C
A
T
T
T
T
G
T
T
A
C
12150
T
G
C
C
C
C
C
C
T
C
T
G
A
A
A
A
C
T
A
A
A
C
T
C
C
A
G
C
C
T
C
A
T
G
A
A
T
G
G
T
A
T
A
C
A
T
G
A
C
C
12200
C
A
A
C
A
T
A
T
C
T
C
T
T
T
C
G
A
T
T
A
A
G
G
A
T
T
T
T
G
C
A
T
T
C
C
T
T
T
A
C
T
A
G
A
A
C
A
G
C
T
12250
T
T
T
T
C
T
C
T
T
C
T
C
C
T
T
T
C
T
T
C
T
T
T
T
C
C
A
T
C
T
A
C
A
G
G
G
G
T
C
C
C
T
T
G
G
G
G
T
A
C
12300
A
G
T
G
G
T
C
C
C
T
T
T
G
G
G
T
G
C
A
T
A
T
A
C
C
C
A
A
A
T
C
C
C
T
G
C
A
T
A
C
T
C
A
A
G
T
C
C
C
A
12350 |
REPEAT
C
A
A
G
C
A
G
C
C
C
T
G
T
G
G
A
A
C
C
A
G
T
G
T
A
T
A
G
G
C
A
G
A
G
T
C
A
G
C
C
C
T
C
T
G
T
A
T
A
C
12400
A
T
G
G
G
T
T
T
G
G
C
A
T
T
C
T
T
C
C
A
T
C
T
G
C
G
T
A
T
A
A
G
T
G
G
A
C
C
A
T
G
T
A
C
T
T
C
A
A
A
12450 |
REPEAT
C
C
T
G
T
G
C
T
G
T
T
C
A
A
G
A
T
T
C
A
G
C
T
G
T
A
C
T
T
G
G
T
C
T
G
T
C
T
T
C
T
C
T
A
G
G
A
A
C
T
12500
T
G
C
T
T
C
T
A
A
A
C
C
C
T
C
C
C
A
C
C
T
C
G
C
A
G
G
T
C
T
T
G
T
G
C
T
C
C
C
T
C
A
G
G
G
A
T
G
G
A
12550
A
C
T
G
T
C
T
T
A
A
T
C
T
C
T
C
A
G
T
T
A
T
C
A
A
A
G
G
A
A
T
G
T
G
A
G
G
T
T
G
T
A
G
A
A
A
T
T
C
A
12600
G
G
T
G
G
G
G
A
A
G
G
A
C
A
T
T
C
C
T
G
G
C
T
G
G
A
A
G
T
A
T
G
T
C
C
T
G
C
A
T
T
G
A
A
A
C
A
G
G
A
12650
T
A
A
T
T
G
T
A
G
T
T
T
T
T
G
T
G
A
A
C
T
A
C
A
G
C
T
G
T
G
T
T
A
A
T
C
A
T
A
C
T
G
C
G
T
T
C
T
T
A
12700
G
A
T
A
G
G
T
T
T
G
C
T
T
C
G
G
A
T
T
T
G
T
G
C
T
T
A
C
C
T
T
T
C
A
C
A
A
A
T
T
T
C
A
T
G
C
T
C
A
G
12750
T
C
T
A
T
T
C
T
G
T
A
T
G
T
G
T
G
T
T
T
T
T
G
C
T
C
T
C
T
A
A
A
T
T
T
T
A
T
A
G
G
C
A
G
T
T
C
A
G
T
12800
A
A
T
C
T
T
A
C
C
A
G
A
A
T
C
T
A
A
A
T
T
C
T
G
T
A
G
A
A
G
A
G
T
T
G
T
C
A
A
A
A
T
C
T
A
C
T
C
C
T
12850
T
A
A
C
A
T
G
G
T
T
A
G
T
G
A
C
T
T
T
A
T
C
T
T
G
C
T
A
G
T
G
C
T
A
A
C
A
T
C
T
T
T
A
T
T
A
A
G
C
T
12900
A
C
C
T
T
G
C
A
A
C
A
G
A
G
T
G
T
G
A
C
A
C
A
T
T
G
A
T
T
T
A
A
T
C
T
T
T
C
A
C
T
T
A
A
T
A
G
G
A
A
12950
T
A
A
T
T
G
A
G
A
A
C
A
G
A
G
T
C
T
G
A
A
G
A
A
C
T
C
T
G
C
A
G
G
A
A
A
C
A
A
A
A
A
T
A
G
T
T
C
C
C
13000
T
G
C
T
T
T
T
A
T
G
A
T
A
G
C
C
A
G
C
C
T
C
T
G
T
A
G
A
G
A
A
A
T
T
C
A
G
T
T
T
T
C
A
A
A
T
C
C
A
A
13050
A
T
A
T
G
A
C
T
T
T
T
A
G
A
A
A
T
T
G
C
A
G
A
T
T
T
G
C
A
A
G
G
A
A
T
T
C
T
A
A
A
G
G
A
A
A
T
A
C
T
13100
T
T
C
A
T
A
A
A
T
A
T
C
A
T
T
T
T
T
C
T
G
T
G
T
A
C
T
T
A
G
T
G
T
A
G
G
A
T
A
G
A
C
A
C
A
A
G
G
G
C
13150
A
A
A
G
A
G
C
A
T
G
A
A
G
A
A
G
A
A
G
A
A
A
G
T
T
C
A
T
G
C
T
C
T
G
T
G
A
C
C
C
A
A
G
C
T
T
G
C
A
G
13200
A
A
C
G
T
T
T
T
A
A
T
G
C
T
G
A
A
T
T
G
T
T
A
A
A
G
C
T
G
T
T
A
T
C
T
A
A
A
T
A
C
T
G
G
T
A
T
A
T
A
13250
T
T
G
C
T
A
G
A
G
A
G
T
T
T
A
G
G
T
A
C
G
T
T
T
T
T
T
T
G
A
G
A
C
A
G
G
G
T
C
T
T
G
T
C
A
T
G
T
T
G
13300 |
REPEAT
C
C
C
A
A
G
C
T
G
A
T
C
T
C
C
T
G
T
G
C
T
C
A
A
G
A
G
A
T
C
C
T
C
C
T
G
C
C
T
C
A
G
C
C
T
C
A
C
A
G
13350
C
T
G
G
A
A
T
T
T
C
A
G
G
C
A
C
A
A
T
A
G
T
G
C
C
A
G
G
C
T
C
T
T
T
G
G
G
A
C
T
T
T
C
A
T
A
G
G
G
A
13400
A
G
C
C
T
G
T
G
A
G
G
G
T
G
C
C
T
G
G
A
A
G
A
G
T
T
C
A
A
T
G
G
A
T
T
C
T
T
T
T
A
G
T
T
T
T
C
T
T
T
13450
T
T
T
A
C
T
T
T
C
T
T
T
C
C
T
T
C
C
T
T
T
T
C
T
C
T
C
T
T
C
T
T
T
T
T
T
C
T
T
T
T
C
T
T
T
T
C
T
T
T
13500
T
C
C
T
T
T
C
C
T
T
T
C
C
T
T
T
A
C
C
T
T
T
C
T
T
T
T
C
T
T
T
C
T
T
T
C
T
T
T
C
T
T
T
C
T
T
T
C
T
T
13550
T
C
T
T
T
C
C
T
T
T
T
C
T
T
T
C
T
C
T
T
T
C
T
T
C
T
T
T
C
T
T
T
C
T
T
T
T
T
C
C
T
T
C
C
T
T
T
C
T
T
13600
T
C
T
C
C
T
G
T
T
C
C
C
T
C
C
C
T
C
C
C
T
C
C
C
T
T
C
C
T
C
C
C
T
C
C
C
T
T
C
C
T
T
C
C
T
T
C
T
T
C
13650
C
T
T
C
C
T
T
C
C
T
T
C
C
T
T
C
C
T
T
C
C
T
T
C
T
T
T
C
T
C
C
T
T
T
T
T
C
T
T
T
G
C
T
T
T
T
C
T
T
T
13700 |
REPEAT
C
T
T
T
T
T
G
A
C
A
G
G
G
T
T
A
C
G
C
T
G
T
T
G
C
T
T
A
G
G
C
T
G
G
A
T
T
C
C
A
G
T
G
G
C
A
C
A
A
T
13750
C
A
C
G
A
T
T
C
A
C
T
G
C
A
G
C
C
T
C
C
G
T
C
T
C
A
T
G
G
A
C
C
C
T
C
A
A
G
G
G
A
T
C
C
T
C
C
C
A
C
13800
C
T
C
A
G
C
C
T
C
C
C
C
A
G
T
A
G
G
T
G
G
G
A
T
C
A
C
A
G
G
T
G
T
G
G
A
C
C
A
C
C
A
C
G
C
C
T
G
G
C
13850
T
A
A
A
T
T
T
G
C
T
A
T
A
A
A
A
A
T
T
A
A
C
A
G
G
T
T
T
T
A
G
C
C
A
A
G
C
A
C
G
G
T
G
A
C
T
C
A
T
G
13900 |
REPEAT
C
C
T
G
T
A
A
T
C
C
C
A
G
C
A
C
T
T
T
G
G
G
A
G
G
C
T
G
A
G
G
C
A
G
G
T
G
G
A
T
C
A
C
C
T
G
A
G
G
T
13950
T
G
G
G
A
G
T
T
C
A
A
G
A
C
C
A
G
C
C
T
G
G
C
C
A
A
C
A
T
G
G
T
G
A
A
A
C
C
C
C
A
T
C
T
C
T
A
C
T
A
14000
A
A
A
A
T
A
C
A
A
A
A
A
T
C
G
C
C
A
A
G
T
G
T
G
G
T
G
G
T
G
G
G
C
G
C
C
T
G
T
A
G
T
C
C
C
A
G
C
T
A
14050
C
T
T
G
G
G
A
G
G
C
T
G
A
T
G
C
A
G
G
A
G
A
A
T
T
G
C
T
T
G
A
A
C
C
T
G
G
G
A
G
G
C
A
G
A
G
C
T
T
G
14100
C
A
G
T
G
A
G
C
C
A
A
G
A
T
C
C
A
C
A
C
C
A
C
T
G
C
A
C
T
A
C
G
T
C
C
T
C
G
G
C
A
A
C
A
G
A
G
T
G
A
14150
G
A
C
T
C
T
G
T
C
T
T
G
A
A
A
A
A
A
G
A
A
A
A
A
A
A
A
A
A
G
C
C
T
C
A
G
T
C
A
T
A
T
G
G
A
T
T
T
G
T
14200
C
C
T
A
G
A
C
T
C
T
G
A
T
T
T
G
T
T
T
A
T
G
A
A
A
C
T
C
C
C
A
C
C
T
T
A
C
T
T
A
T
G
T
A
A
G
G
A
A
A
14250
C
T
T
T
T
T
T
T
T
T
T
T
G
G
T
C
A
T
A
T
T
A
A
C
C
T
G
T
C
T
A
T
T
G
C
C
A
G
T
T
T
A
A
T
T
T
C
T
A
G
14300
G
A
A
C
C
C
A
G
C
T
A
G
G
G
A
A
C
C
C
A
C
A
G
G
G
G
A
G
A
T
G
G
A
A
A
A
G
G
A
T
T
T
T
T
T
C
T
T
C
T
14350
C
T
A
A
A
G
T
A
A
C
A
T
T
T
A
A
G
A
A
A
A
C
C
T
A
A
C
A
G
C
G
A
T
A
C
G
T
T
G
T
T
G
C
A
A
A
C
T
G
A
14400
A
G
A
C
C
C
A
A
G
G
A
G
G
G
T
G
G
G
C
A
G
G
T
T
T
G
T
C
A
T
C
C
A
T
G
A
G
T
C
T
T
G
G
T
T
G
G
T
T
C
14450
T
G
A
T
T
T
A
A
C
A
A
A
A
G
T
T
C
A
T
C
C
C
T
C
T
C
A
A
A
G
C
C
T
T
A
A
C
C
T
T
T
G
A
T
G
T
C
C
C
C
14500 |
REPEAT
A
C
T
G
T
C
A
T
T
G
C
C
T
C
T
G
T
T
A
T
C
C
A
A
G
C
A
T
G
G
C
T
C
C
C
C
T
G
G
A
T
T
T
T
T
G
C
A
G
T
14550
T
A
C
C
T
C
C
C
C
G
C
T
A
G
T
C
C
T
T
G
C
T
T
C
C
A
C
A
C
T
T
G
C
C
T
C
T
C
C
C
T
C
C
T
C
C
T
G
T
T
14600
G
T
T
C
T
C
C
A
C
A
C
A
G
C
A
G
A
G
T
G
T
T
C
C
T
T
T
A
T
T
T
A
T
T
T
A
T
T
G
A
G
A
C
A
G
G
G
T
C
T
14650 |
REPEAT
T
G
C
T
C
T
G
T
T
G
C
C
C
A
A
G
C
T
G
G
A
G
T
G
C
A
G
C
A
G
C
A
C
A
A
T
C
T
T
A
G
C
A
C
A
C
T
G
C
A
14700
A
T
C
T
C
T
G
C
C
T
T
C
T
G
A
A
T
T
C
A
A
G
C
G
A
T
T
C
T
C
C
T
G
C
C
G
T
C
C
C
G
A
G
T
A
G
C
T
G
G
14750
G
A
T
C
A
A
A
A
A
T
G
C
A
C
A
C
C
A
C
C
A
C
G
C
C
C
G
G
C
T
A
A
T
T
T
T
T
G
T
A
T
T
T
T
T
A
G
T
A
G
14800
A
G
A
C
G
G
G
G
T
T
T
C
A
C
C
A
T
G
T
T
G
G
C
C
A
G
G
G
T
G
G
T
C
T
T
G
A
A
C
T
C
C
T
G
A
C
C
T
C
A
14850
A
G
T
A
A
T
C
T
G
C
T
C
A
C
C
T
C
A
G
C
C
T
T
C
C
A
A
A
G
T
G
C
T
G
A
G
A
T
T
A
C
A
G
G
C
A
A
G
A
G
14900
C
C
A
C
C
G
C
A
C
C
T
G
G
C
C
T
G
G
C
C
C
A
G
A
G
T
G
T
T
C
C
T
T
T
A
T
A
A
A
C
A
T
C
A
T
T
A
G
G
G
14950 |
REPEAT
T
T
G
T
G
A
G
C
C
T
T
T
C
C
T
G
A
T
T
A
A
A
A
G
G
C
C
T
C
A
G
T
G
G
C
T
T
C
T
C
A
C
T
G
A
C
C
A
T
A
15000
C
A
G
C
C
C
T
T
T
G
G
T
G
A
T
G
G
G
G
T
C
T
C
T
T
C
C
T
G
T
C
T
G
T
C
G
G
G
A
A
T
T
A
G
G
C
C
G
C
G
15050
T
T
C
T
C
C
A
G
A
T
C
A
C
T
G
T
G
C
T
G
C
C
A
T
G
A
T
G
T
G
G
G
G
T
C
C
T
A
G
A
G
C
A
C
C
T
A
G
C
C
15100
A
G
T
T
T
A
A
C
T
C
T
G
A
A
A
C
C
A
C
C
A
T
A
C
A
A
G
C
A
G
G
C
T
T
T
G
G
G
C
C
T
G
A
A
T
A
T
A
A
T
15150
C
A
A
C
A
C
T
G
G
A
C
C
T
C
T
C
A
G
G
A
C
A
A
A
T
C
T
G
T
C
A
A
A
T
C
G
G
A
T
A
T
A
A
C
A
T
G
A
A
A
15200
G
C
C
C
A
T
G
G
A
T
C
A
A
C
C
T
T
T
T
A
A
A
G
G
C
A
A
T
A
A
A
A
T
A
C
C
A
T
G
A
T
A
C
C
T
T
T
T
A
A
15250
A
G
A
C
A
A
G
G
G
A
C
A
A
T
T
T
A
T
G
T
A
A
G
T
T
A
A
A
C
T
T
C
A
G
A
T
T
T
T
G
T
G
T
T
C
C
T
T
T
T
15300
C
C
T
T
T
C
C
A
C
T
G
C
T
A
A
G
T
T
T
G
T
A
G
C
A
A
T
C
G
C
C
T
G
A
C
A
G
T
G
A
T
T
T
G
A
T
T
G
C
T
15350
C
A
G
G
A
T
T
G
T
T
A
T
C
T
T
T
T
G
A
G
A
T
T
A
A
C
C
T
C
A
G
T
A
A
A
C
A
C
T
T
T
A
A
A
G
A
G
G
T
A
15400
T
G
T
A
A
T
T
T
A
T
G
C
A
G
C
A
T
G
C
C
C
T
A
T
G
G
C
T
A
T
G
A
G
G
T
A
G
A
G
T
G
C
A
A
C
T
C
C
A
T
15450
A
T
A
C
T
A
G
C
G
T
C
A
T
C
C
T
A
G
G
A
A
A
A
A
A
A
A
A
A
G
G
A
A
G
A
G
T
A
G
A
G
T
C
T
G
G
A
A
T
T
15500
C
T
C
A
A
C
T
T
G
A
G
G
C
T
A
T
C
T
T
G
G
C
T
T
C
T
A
C
C
A
A
C
A
A
A
T
G
C
A
G
T
A
G
T
T
C
C
A
G
C
15550
T
G
G
G
C
A
G
G
T
G
G
C
A
G
G
C
T
G
A
A
G
A
C
T
T
T
A
G
G
C
T
C
T
A
C
C
T
G
T
G
C
A
C
T
T
T
T
T
T
T
15600
T
T
T
T
T
C
C
T
C
T
T
C
T
C
A
G
T
T
T
T
C
A
T
T
G
T
A
T
G
A
A
A
A
T
G
T
T
G
T
T
T
T
G
A
G
T
T
G
C
G
15650
C
A
A
T
T
T
G
A
G
C
T
T
T
C
C
A
A
T
T
G
T
A
A
A
G
A
G
T
G
T
T
C
T
A
T
A
C
A
A
T
T
A
A
G
A
G
T
T
T
G
15700
A
T
A
A
A
G
A
G
T
A
A
A
A
A
A
A
T
T
G
A
G
A
A
A
T
A
C
G
G
T
A
T
C
T
G
T
A
A
T
G
C
A
G
A
T
T
A
T
C
A
15750
T
T
T
T
T
A
T
A
A
T
A
G
A
G
T
A
C
C
A
G
C
A
T
A
T
A
T
T
G
A
A
G
A
C
A
A
A
T
G
G
T
T
A
A
A
C
T
T
C
T
15800
C
A
A
A
A
A
A
G
T
A
A
A
A
A
T
G
T
G
C
T
G
G
G
C
G
C
A
G
T
G
G
C
T
C
A
C
A
C
C
T
A
T
A
A
T
C
C
C
A
G
15850 |
REPEAT
C
A
C
T
T
T
T
G
G
A
G
G
C
C
G
A
C
G
T
G
G
G
C
G
G
A
T
C
A
C
C
T
G
A
G
G
T
C
A
G
G
A
G
T
T
T
G
A
A
A
15900
C
C
A
G
C
C
T
T
G
A
C
C
A
C
C
A
T
G
G
T
G
A
A
A
C
T
T
C
G
T
C
T
C
T
A
C
T
A
A
A
A
A
T
A
C
A
A
A
A
A
15950
T
T
A
G
T
T
G
G
G
C
G
T
T
G
T
G
G
C
A
T
C
G
G
C
C
T
G
T
A
A
T
C
C
C
A
G
C
T
A
C
T
A
G
G
G
A
G
A
C
T
16000
G
A
G
G
C
A
G
G
A
G
A
A
T
C
A
C
T
T
G
A
A
C
C
C
G
G
G
A
G
G
C
G
G
A
G
G
T
T
G
C
A
G
T
G
A
G
C
C
T
A
16050
G
A
T
C
A
T
G
C
C
A
T
T
G
C
A
C
T
C
C
A
G
C
C
T
G
G
G
C
A
A
C
A
A
G
A
G
T
G
A
A
A
C
T
C
C
A
T
C
T
C
16100
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
G
T
A
A
A
A
A
T
G
T
G
G
C
C
T
T
G
C
T
A
G
T
T
A
G
G
A
16150
A
G
C
A
A
C
A
A
G
A
A
A
G
G
C
G
A
G
G
T
A
T
G
A
A
T
G
A
C
A
T
A
G
G
T
A
G
A
C
C
A
G
C
A
C
G
A
A
A
G
16200
A
G
G
C
A
G
C
A
G
A
G
C
T
G
G
G
G
A
A
A
G
A
A
T
C
T
C
C
A
T
A
T
G
C
A
A
A
T
C
C
C
T
T
C
T
G
T
C
T
T
16250
A
T
T
T
G
A
A
A
G
G
G
C
T
T
T
T
T
G
A
G
T
T
G
G
C
T
A
A
G
A
T
A
C
A
T
A
A
T
C
A
G
G
C
C
A
A
A
T
A
A
16300
C
A
T
G
A
A
T
C
G
G
C
T
G
G
G
A
T
C
A
G
G
T
A
A
A
G
T
G
T
A
A
A
G
C
C
A
T
T
T
G
A
A
G
G
C
T
T
C
C
T
16350
T
T
C
A
C
T
T
A
A
G
G
C
T
T
T
G
C
A
G
G
G
G
G
T
C
T
A
G
G
A
C
A
C
A
G
A
A
A
G
A
G
A
A
A
A
A
G
A
A
A
16400
T
G
G
A
T
T
A
G
C
C
T
T
A
G
C
A
G
G
T
A
A
T
C
T
G
C
A
A
A
T
A
A
G
G
A
A
A
C
G
G
C
A
A
C
A
G
G
T
G
G
16450
G
A
G
G
T
T
G
A
T
T
T
T
T
G
T
T
G
T
A
G
G
G
A
C
A
T
C
T
C
G
T
T
G
T
G
T
G
A
T
G
G
G
T
A
T
T
T
T
C
C
16500
T
T
G
A
T
A
T
A
A
A
A
A
G
A
T
G
A
T
G
C
T
A
A
T
C
C
A
A
T
G
A
G
A
T
C
A
G
C
A
C
A
C
A
T
G
T
C
C
A
G
16550
A
A
A
G
C
T
T
C
T
G
A
C
C
A
T
G
G
G
G
A
A
A
G
A
C
T
G
G
T
G
T
T
T
G
C
T
T
A
A
A
G
G
T
A
G
T
T
G
T
T
16600
A
C
T
T
T
T
A
G
A
G
A
G
T
T
C
C
C
T
A
A
A
C
C
C
A
G
A
A
T
A
C
T
A
T
A
T
T
C
A
T
T
A
G
A
G
A
T
C
G
G
16650
G
C
A
C
T
T
T
G
A
G
A
T
G
A
G
T
C
T
G
G
T
G
C
T
G
A
G
T
T
G
G
T
A
T
A
T
T
T
T
A
T
T
T
A
T
T
T
A
A
T
16700
C
C
T
T
A
C
T
A
T
G
T
T
T
T
T
T
T
T
C
T
T
A
G
A
G
T
A
A
G
T
G
T
A
T
T
G
C
T
C
C
A
T
A
T
T
G
G
T
G
T
16750
T
A
G
A
A
T
T
A
A
A
G
T
T
T
G
T
T
T
T
T
T
T
T
C
C
T
T
T
C
T
T
T
T
TGATGTA ACGTGCTTCA
16800
GCTTGATGGT GTGCCTTGGT TATACCTGTC TAATCACTTG GTTTGTGACT
16850
CATGAATGAC TAAGGCCCTG TATCTCCCGA GGAAGATTGT TAGAATCCTA
16900
GCCAGGAATG AAACAGCTCC TGAGTAATGT GAATTACACA TTTAATCCTA
16950
TCACAGGAAA GGCAAACTCT TT
C
TCTGCAG GCACTTCTAA GATTGTGATT
17000 |
var(16973):[G:0.01]
GTATTTATAA GTGTTACCCT CTGTCTTGTA TGGGCATGG
G
TGATCACTCT
17050 |
var(17040):[C:0.01]
TTCTTGGGTA CTTTAGCTCT AGTTGTTGCC TTTTATTTGT GGAAACCTCA
17100
CAAAAGTGTC TTTAAAATTT CC
A
TCTTGAG TCAGTGAGCT ATT
T
AAATTC
17150 |
var(17123):[G:0.43]
|
var(17144):[G:0.40]
AAGCAATAAG TTATTTGATA CTCTTAAGAA GTCTTTTCCT CAGTGGCTGA
17200
AGGAACATCA AATGGGGATG GCAGTAGAAG AAGTGATTGC TAGTGTTGGA
17250
ATTGGTGTAT TTTGGTTTCT GAATACATGG GGAGATGGTT TAAAACCTTT
17300
TTGAAGTAAA GGTGTGAAGT CCATACATTA
C
A
G
T
T
A
T
C
T
C
T
A
G
A
G
A
T
C
C
C
17350 |
REPEAT
T
G
G
G
G
A
A
T
T
G
G
T
T
C
C
A
A
G
A
C
T
C
C
C
C
T
C
A
G
A
C
A
C
C
C
A
A
A
T
C
C
A
C
A
T
A
T
G
C
T
17400
C
A
A
G
T
T
C
C
T
G
A
T
A
T
A
A
C
A
T
G
G
C
A
T
A
G
T
A
T
T
T
G
C
A
T
A
T
A
A
T
G
T
A
C
A
C
G
C
A
T
17450
T
G
T
T
C
C
A
T
A
T
A
C
T
T
T
A
A
A
T
C
A
T
C
T
C
T
A
G
A
T
T
A
C
T
T
G
T
A
A
T
A
C
C
T
A
A
T
A
C
A
17500
A
T
G
T
A
A
A
T
G
T
T
A
T
G
G
T
A
A
T
A
G
T
T
G
T
G
A
T
A
C
T
A
T
A
T
T
G
T
A
T
A
G
G
A
A
A
T
A
A
T
17550
G
A
T
G
A
A
A
A
A
A
T
T
C
T
G
T
A
T
A
T
G
T
T
G
T
G
T
A
C
A
G
G
C
A
C
A
G
C
C
A
T
C
C
A
T
T
T
A
T
A
17600
T
T
T
A
T
T
T
T
T
A
A
A
T
A
T
T
A
A
T
T
T
T
T
T
T
G
A
G
A
T
G
G
G
G
T
A
T
T
A
C
T
C
T
G
T
T
A
C
C
C
17650 |
REPEAT
A
G
G
C
T
A
G
A
G
T
G
C
A
G
T
G
G
C
A
T
G
A
T
C
T
C
G
G
C
T
C
A
C
T
G
C
A
A
T
C
T
C
T
G
C
C
T
C
C
T
17700
G
G
G
C
T
C
A
A
G
T
G
A
T
C
C
T
C
C
T
G
C
C
T
C
A
G
C
C
T
C
C
C
G
A
G
T
A
G
C
T
G
A
A
A
C
C
A
T
G
G
17750 |
var(17740):[C:0.28]
G
T
G
T
G
C
A
C
C
A
G
C
A
T
A
C
T
C
G
G
C
T
A
C
T
T
T
T
T
T
G
T
A
T
T
T
T
T
G
A
T
A
G
A
G
A
T
G
G
G
17800
G
T
T
T
C
A
C
C
A
T
G
T
T
G
T
G
C
A
G
G
C
T
G
G
C
C
T
C
G
A
A
T
T
C
C
T
G
C
G
T
T
C
A
A
G
T
G
A
T
C
17850
T
G
C
C
T
G
C
C
T
T
G
A
C
C
T
C
C
C
A
A
A
G
T
G
C
T
G
G
G
A
C
T
A
C
A
G
G
T
G
T
G
A
A
C
C
A
C
C
A
C
17900 |
var(17874):[T:0.40]
G
C
C
T
G
T
C
C
T
A
T
T
T
T
T
T
A
A
T
A
T
T
T
T
C
G
A
T
T
T
G
C
G
A
C
T
G
G
T
T
G
A
A
T
C
T
T
C
A
G
17950 |
REPEAT
A
T
G
C
A
G
A
A
C
T
C
A
A
G
G
A
C
A
G
G
G
C
T
G
C
T
G
A
C
T
G
TACTTGTGC CTTCTCTTTC
18000
ACTGCTTCAA GAGAACAGAA TTTTGGCTAA TTATTACCAT TCATTGTGTT
18050
CACAGATTAA AACCCAGCCA TGTACCTTGA ATTTGCTGGG TGTCAGTCTT
18100
TAAATGGTTT CTACTTTTCC AGACTCCAAA TGAATAGACT TGTAAATATG
18150
ATTATGTTTC TGGATTACAG AAACAGTTAT TAGGAGA
T
A
A
C
T
T
T
G
G
T
T
T
T
18200 |
REPEAT
T
G
G
C
A
G
T
T
T
T
A
T
T
A
T
G
A
T
A
T
G
C
C
T
A
G
A
T
T
T
G
T
C
T
T
T
T
T
T
T
G
T
A
T
T
C
A
T
C
C
18250
T
C
T
T
T
G
G
T
G
T
T
C
C
T
A
G
A
G
T
T
T
C
T
T
C
A
A
T
C
T
G
T
G
G
C
T
T
G
A
T
A
C
C
T
T
T
G
T
C
A
18300
G
T
T
T
T
G
G
A
A
A
A
T
A
C
T
G
G
C
C
A
G
T
A
T
T
T
C
T
T
C
A
A
A
T
A
C
T
G
A
T
T
C
T
G
T
C
T
A
A
G
18350
T
A
C
C
C
A
T
T
T
T
G
C
T
G
C
A
T
T
T
T
C
C
C
T
T
C
T
C
T
C
T
C
A
G
G
T
T
G
C
C
T
G
T
T
A
T
G
C
G
T
18400 |
var(18362):[T:0.24]
A
T
G
A
C
A
G
A
C
C
T
T
T
T
T
C
A
T
C
T
T
A
T
C
C
C
A
T
A
T
G
T
T
T
G
T
T
A
T
G
C
T
C
T
T
T
T
A
T
G
18450
T
A
G
T
T
C
T
C
A
T
T
C
T
T
T
T
T
AAT TAGGAGATTT TT
T
CCCCCTT TCATGGTAAT
18500 |
var(18483):[:0.38]
AATTTTCATC ATTCATAATT TTCA
T
C
C
T
G
G
A
T
G
T
T
T
T
C
T
G
T
G
T
A
C
T
A
G
T
C
18550 |
REPEAT
T
T
C
C
A
G
T
T
C
A
C
T
A
A
A
T
T
C
T
C
T
T
T
C
C
T
A
A
T
T
T
G
T
G
T
C
T
A
A
A
C
T
A
G
G
A
A
A
G
C
18600
T
G
C
T
G
T
T
A
A
A
C
T
C
A
T
C
G
A
T
T
G
A
A
T
T
C
T
T
A
A
T
T
T
T
TGTTTG TTTTTGTAGA
18650 |
var(18619):[C:0.01]
TCTTTGTTCC TTGGTGAGAG TCTGTCTTTT AATTTTCTTA AACACATCAA
18700
TCTTTTGTTT TAATGTCAAT GTCTGTTAAC TCCAGTCTAG ATTACTTGTG
18750
GGTCTGTTTC CATTTTCTCA TTTCCGGAAC ATCAGGTTCT GTTTTTTGGC
18800
ATGCCTGGCA ATTT
T
AAAAA TTTTTTTCAT TATTTTTAAA CTT
A
T
G
A
T
T
C
18850 |
var(18815):[A:0.03]
|
REPEAT
G
T
G
A
A
T
C
A
G
G
C
A
G
C
C
T
T
C
A
G
A
A
T
C
A
C
A
G
C
A
G
A
T
T
C
A
G
A
G
A
G
A
T
T
C
C
T
G
A
T
18900
G
C
C
T
GGCAAT TTTTTATTGA AAATTTGGAT GATATCTTCA TAGAGAGTGG
18950
ATTTAACCTT CTTCTAGCAG TCTGAGCAGA TCGCCATGAT TGAGTAGACT
19000
GGTTTTTTGG TTTGTCCACA TTCCCAGAGC ATAATGCTTT TGGGATCTCT
19050
TTCCAGGGCT CCTCCTCTGT TAGGCACTCA ACACCAACAA AATTTTGTCT
19100
CCCTAGTGCT GACAGACTGC TGAAATATCT GCTCAGAAAT AGTAGAGGCT
19150
TCAGTAAGCC GACTCATTTC TTCTAGCAGC TTCTTCCTGC TTGGTTTGTC
19200
TGAGCTGTGC C
C
CAGGTGTG TACAATTTTT GTGTGCAAAT ACCCACCTTA
19250 |
var(19212):[A:0.37]
AGAGGAAAGG GCACGCGGAA TGCAGAGTTT GTTTCAGTGC TTCAGTCCCG
19300
CCATTCCGTG ATTTTGGTTC CTCATGTCCT GGCCGCTTTG GTTGCTTTTA
19350
TCAG
A
CAGAA CTCTTCAACA GTTTCTTCTT ACTTTTTTTG GTCTACTTTT
19400 |
var(19355):[G:0.02]
GTCGTTGTGC TTAGGAGGAC TGTTTGGGAA CAGCAACTC
A
ATCATAGGCA
19450 |
var(19440):[C:0.45]
GAGAGAAAGT TCGTCATGGA TTACTTTGAC TTTTAAAAAT TAAAACTACA
19500
TTTATTGAAG TTAACATTTC AAACCTGTTT CACAA
G
TTGT TAAGCTCATC
19550 |
var(19536):[A:0.02]
TTAAGGTCTT ACTCAAATAA ATCTTTTTTG AGGCCTTTTG TAATTTGTTT
19600
AATGAAATAG TTCACATTTT ATTGATACAT TTAATATTCT TTTTTGTTT
T
19650 |
var(19650):[C:0.36]
AAATTTTTGC TCAACTTTTG GTTTGATTTA CTTAATGATT TTCGTACCTA
19700
ACTTTAAATC TCCCTAGAAT TTAAATATAC TTATTAATTA AGGAAATTAT
19750
TATGTAATTG CAAACAATTT TGGAGTTTAC CTTCTTTGCT GATTGAAGGT
19800
GCATAACAAC TTCC
G
ACATA AAGTCTGGAG CTATAAATTC AGAGAAATGT
19850 |
var(19815):[T:0.47]
CTCCTGTTCC TGACTGCTTG GCTAAGCCCC TTTTGATAAT AATGATGCTA
19900
TAAACTCCGC AATTAAAAAA AATAGAG
T
T
T
C
T
T
T
T
T
T
T
T
C
C
C
T
T
T
G
T
T
T
T
19950 |
REPEAT
T
G
A
G
A
T
G
G
A
G
T
C
T
C
G
C
T
C
T
A
T
C
G
C
T
C
A
G
G
C
T
G
G
A
G
T
A
C
A
G
T
G
G
C
A
C
G
A
T
C
20000 |
var(19965):[A:0.09]
T
C
T
G
C
T
C
A
C
C
G
C
A
A
C
C
T
C
T
G
C
C
T
C
C
C
T
G
G
T
T
C
A
A
G
C
C
A
T
T
C
T
C
C
T
G
C
C
T
C
20050
A
G
C
C
T
C
C
C
A
A
G
T
A
G
C
T
G
G
G
A
T
T
A
C
A
G
G
C
A
C
A
C
G
C
C
A
C
C
A
C
A
C
C
T
G
G
C
T
A
A
20100
C
T
T
T
T
G
T
A
T
T
A
T
T
A
G
T
A
G
A
G
A
C
A
G
G
G
T
T
T
C
A
C
C
A
T
G
T
T
G
G
C
C
A
G
G
C
T
G
G
T
20150
C
T
T
G
A
A
AAAA AATACAGAGA TTCTGATGAT GAGCATGTAG TCTGTCCCTG
20200
CACTTGACTT ATATCATAAT ATGCTTTTCA AGCCAGACAA GTCTAACCCT
20250
CATCCATCCT TTTCCTGCTT TATCAGTTTT TTGTAATTTT CATACTCTTC
20300
CTATTTACTT ATTAGGACCC ATTTACTTAT TAGGGATGTA TTTG
A
CATCT
20350 |
var(20345):[G:0.01]
AATTGGAGTT TATGCATTCC AAGTTGTGCC TGTCTTCCCA TTTAGGTTTT
20400
TAGGATGTTC TTATCACAAT GGTATGGGCC ATTCATTGGA AATGAAGCTG
20450
CTCATTGCC
G
CACATTTAAA AATGGACTTG TTTTAAATGT ATTGTCACCT
20500 |
var(20460):[A:0.33]
AGTGTTTGCA ATCTCATTTA TCTGGACTAT CAACTTACTA TTGCTTTTCT
20550
GTCTGCAG
A
A
A
G
A
T
A
A
A
A
A
C
T
C
T
C
C
A
G
A
T
G
T
C
T
T
C
C
A
G
T
A
A
T
G
T
C
G
A
A
G
T
20600 | Exon 2 |
UTR
M S S S N V E V 8
T
T
T
T
A
T
C
C
C
A
G
T
G
T
C
A
C
A
A
G
G
A
A
A
C
A
C
C
A
A
T
G
G
C
T
T
C
C
C
C
G
C
G
A
C
A
G
C
T
T
20650 |
var(20611):[A:0.02]
F I P V S Q G N T N G F P A T A 24
C
C
A
A
T
G
A
C
C
T
G
A
A
G
G
C
A
T
T
T
A
C
T
G
A
A
G
G
A
G
C
T
G
T
G
T
T
A
A
G
T
T
T
T
C
A
T
A
A
C
20700
S N D L K A F T E G A V L S F H N 41
A
T
C
T
G
C
T
A
T
C
G
A
G
T
A
A
A
A
C
T
G
A
A
G
A
G
T
G
G
C
T
T
T
C
T
A
C
C
T
T
G
T
C
G
A
A
A
A
C
C
20750
I C Y R V K L K S G F L P C R K P 58
A
G
T
T
G
A
G
A
A
A
G
A
A
A
T
A
T
T
A
T
C
G
A
A
T
A
T
C
A
A
GTATGTACAT GAACTTGTAA
20800
V E K E I L S N I N 68
AAAGACAGCT TTTTA
A
TTTA CCTACAGTGA ACCTCA
C
A
G
G
T
T
T
T
G
G
C
T
A
T
20850 |
var(20816):[G:0.02]
|
REPEAT
T
T
C
C
A
A
G
A
A
A
C
T
G
G
C
T
A
T
G
A
A
C
A
T
T
T
T
T
G
T
A
C
A
A
G
T
C
T
T
T
G
C
A
C
A
G
A
T
A
T
20900
A
C
A
G
A
C
A
C
A
T
G
C
T
T
T
C
A
T
T
T
G
T
T
T
T
A
G
C
T
A
A
A
C
T
A
G
G
A
G
T
G
A
A
A
T
A
A
T
T
G
20950 |
var(20927):[A:0.01]
|
var(20948):[C:0.08]
G
G
C
C
A
C
A
T
T
T
T
A
G
G
T
A
T
A
T
G
T
T
T
A
A
C
T
C
T
C
A
A
A
G
T
A
A
C
T
G
C
C
A
G
A
C
T
T
T
T
21000 |
var(20974):[G:0.08]
T
T
A
A
A
A
A
A
T
G
CACCACATGT
G
G
C
T
G
G
A
T
A
T
G
G
T
G
G
C
T
C
A
T
G
C
C
T
G
T
A
A
T
C
21050 |
REPEAT
C
C
A
G
C
A
C
T
T
T
G
G
G
A
G
G
C
C
G
A
G
G
C
A
G
G
C
A
G
A
T
C
A
T
G
A
A
G
T
C
A
A
G
A
G
A
T
C
G
A
21100
G
A
A
C
A
T
C
C
T
G
G
C
C
G
A
C
A
T
A
G
T
G
A
A
A
C
C
C
T
G
T
C
T
C
T
A
C
T
G
A
A
A
A
T
A
C
A
A
A
A
21150 |
NOT SCANNED
A
A
T
T
A
G
C
T
G
G
G
C
G
T
G
G
T
G
G
T
G
T
G
T
A
C
C
T
G
T
G
A
T
C
C
C
A
G
C
T
A
C
T
T
G
G
G
A
G
G
21200
C
T
G
A
G
G
C
A
G
G
A
G
T
A
T
G
G
C
T
T
G
A
A
T
C
T
G
G
G
A
T
A
T
C
A
A
G
T
C
T
G
C
A
G
T
G
G
G
C
G
21250
A
T
G
A
T
T
G
T
C
C
C
A
C
T
G
T
A
C
A
A
A
T
A
G
G
T
G
G
C
A
A
A
G
T
G
A
G
A
G
C
C
T
A
T
C
T
T
A
A
A
21300
A
G
A
A
A
A
A
G
A
A
A
A
A
G
C
G
T
A
C
T
T
T
G
T
G
A
G
G
G
T
G
C
A
T
T
T
A
T
T
T
T
G
C
T
T
A
T
T
T
T
21350
A
T
C
T
T
T
T
A
A
A
G
T
T
A
G
T
A
G
A
T
G
A
G
T
A
A
C
T
T
G
A
T
G
C
A
C
T
A
G
A
A
G
T
C
T
C
G
T
C
T
21400
G
C
T
C
A
AGGCT TCACAC
T
T
T
T
T
T
T
T
T
T
T
T
T
T
T
T
G
A
G
A
G
G
G
A
G
T
C
T
C
G
C
T
C
T
21450 |
REPEAT
A
T
C
A
C
C
C
A
G
G
C
T
G
G
A
G
T
G
C
A
G
C
A
G
C
A
C
A
A
T
C
T
C
G
G
C
T
C
A
C
T
G
C
A
A
C
C
T
C
C
21500
A
C
C
T
C
C
C
G
G
G
T
T
C
A
A
G
T
G
A
T
T
C
T
C
C
T
G
C
C
T
C
A
G
C
C
T
C
C
C
G
A
G
T
A
G
C
T
G
G
G
21550
A
T
T
A
C
A
G
G
T
G
T
G
T
G
C
C
A
C
C
A
T
G
C
C
T
G
G
C
T
A
A
T
T
T
T
T
G
T
A
T
T
T
T
T
A
G
T
C
A
A
21600
G
A
T
G
G
G
G
T
T
T
C
A
C
C
A
T
G
T
T
G
G
C
C
A
G
G
C
T
G
G
T
C
T
T
G
A
A
C
T
C
C
T
G
A
C
C
T
C
A
T
21650
G
A
T
C
C
A
C
C
C
G
C
C
T
C
A
G
C
C
T
C
C
C
A
A
A
G
C
A
C
T
G
G
G
G
T
G
T
G
A
G
C
C
A
C
T
G
T
G
C
C
21700
A
G
G
C
C
ACGCA TTTTTTTTTA TGGTCAAATG GCATGCATTT CAGCAATAGA
21750
TGAGTTCATC TTTACTGCAT GAATAGAACT GTGTTCCTTA CTAGGCTCAT
21800
AAAAATG
C
AG TCAGATCTTG CAATTCTTTC ACATTTTAGT GGAAAGGTCA
21850 |
var(21808):[T:0.23]
TCAGGGGTTG GTGTTTTTGC TGCTGGCATT TCCTGTTTAA GTATCCATGA
21900
GAAAG
G
CCTT TTTGGCTGTA GTATTTCCAG TCTTTCTCCT ATCTGCTGGC
21950 |
var(21906):[A:0.13]
TCCAACTCTA AATACAGTTT CTGGAGGTAG AGGAAGGGCT GCTGTCATTT
22000
ATCTTACTTT TGATTTGTGT TTGATAGCAG CATCACCATT CAGATAGTCA
22050
TCTACATTCC AAAAAAGCTG ATGAGAATTT TGATTTTGGT TTTTCCTCTG
22100
GACATTTTGT AATTTCACTT CTAGAACTAA GTCACTATAA CCTGATTTCC
22150
TCTGCAGGGG GAAGAAGATA AAAACAGTCT GACCATGAGA ATTTAAAAAG
22200
TTGTGATTCT TCTGACTTAG GACAAATCTT TCTCTTATGC TTGTTTGTCT
22250
CCATACCCAG CATTTGAGCT TTCCCTCACC AACGCTGAAG ATCTTATGGA
22300
AAAAAAAATT CATTCCCATA GATATGTGGA TGTCCTGTTA TTTTAAGAGA
22350
AATTCATTAT ACTCTTGGAA CATTTTTAAT TAATAAC
T
T
A
T
T
T
T
G
A
A
A
T
G
22400 |
REPEAT
|
var(22391):[C:0.03]
A
T
T
T
C
A
A
A
T
T
T
A
T
T
T
A
T
T
T
A
T
T
T
T
T
T
A
G
A
G
A
T
G
G
A
G
T
C
T
T
G
C
T
G
C
A
T
C
A
C
22450 |
REPEAT
|
var(22439):[C:0.08]
C
T
A
A
G
C
T
G
G
A
G
T
G
T
G
G
T
G
C
T
G
C
A
A
T
C
A
T
A
G
C
T
C
A
C
T
C
T
A
A
G
C
T
C
C
A
A
C
T
C
22500
C
T
G
G
G
C
T
C
A
A
G
T
G
A
T
T
C
T
C
C
C
G
C
C
T
C
A
G
C
C
T
C
T
G
G
A
G
T
A
G
C
T
A
G
A
T
G
C
C
A
22550
C
A
A
T
G
C
C
T
G
G
C
T
A
A
T
T
A
A
A
A
A
T
T
T
T
C
T
G
T
G
T
G
T
G
G
A
G
A
T
G
G
G
G
T
C
T
T
C
C
T
22600
A
C
G
T
T
G
C
C
C
A
G
G
C
T
G
G
C
C
T
T
G
A
A
C
T
C
C
T
G
G
G
C
T
T
A
A
G
T
G
A
T
C
C
T
C
C
C
A
C
C
22650 |
var(22601):[G:0.01]
|
var(22638):[C:0.12]
T
T
G
G
C
C
T
C
C
C
A
A
A
G
C
A
C
T
G
G
G
G
T
T
A
T
A
A
G
C
A
T
G
A
G
C
C
A
C
T
G
C
A
C
C
T
G
G
C
C
22700 |
NOT SCANNED
T
G
A
T
G
T
T
A
A
A
T
T
T
A
A
A
C
G
T
T
T
C
A
G
G
A
A
C
A
T
A
A
C
C
C
T
T
T
T
C
A
T
T
C
A
G
G
T
T
C
22750 |
REPEAT
T
C
A
G
C
C
A
A
C
A
T
T
T
C
A
C
T
G
C
A
T
T
T
G
T
T
C
T
C
A
T
C
A
C
T
T
T
G
T
C
T
C
T
T
C
A
T
G
T
T
22800
C
C
C
A
T
G
G
T
C
A
T
T
A
C
T
G
T
T
T
T
T
T
C
T
G
A
A
C
C
G
T
G
T
G
A
G
T
G
C
A
G
G
C
T
G
T
C
C
A
C
22850
A
T
G
G
T
G
C
T
T
C
C
T
T
C
T
C
C
T
T
A
A
C
T
C
C
T
T
T
G
T
G
T
G
T
G
T
T
C
T
T
G
A
A
A
A
A
A
C
G
A
22900
C
C
C
T
C
T
C
C
T
A
T
A
T
A
A
C
C
A
C
T
C
A
G
A
C
A
T
T
G
T
C
C
A
G
G
A
G
G
A
G
C
C
A
A
G
G
G
G
A
A
22950
A
T
G
T
A
G
C
C
T
T
G
T
A
A
T
G
A
A
G
G
T
C
G
T
G
G
T
A
G
G
T
C
C
T
C
A
G
G
G
C
C
T
T
G
G
G
T
C
A
A
23000
C
C
A
T
G
C
C
C
C
T
C
A
C
A
T
A
T
T
T
G
A
C
T
G
C
C
A
C
C
A
T
A
T
C
C
T
G
T
C
T
C
T
T
C
A
G
T
C
T
C
23050
A
T
T
C
A
A
C
G
T
G
G
T
A
T
T
T
T
C
T
T
A
T
C
T
C
A
T
C
C
C
A
C
C
C
C
T
G
G
T
G
A
T
G
T
T
A
A
A
A
T
23100 |
REPEAT
T
G
A
T
C
A
C
T
T
G
G
T
C
A
T
G
T
T
G
A
T
G
T
C
T
G
C
C
A
A
A
C
T
T
G
G
C
T
A
T
A
A
T
G
T
C
A
C
C
C
23150
T
T
T
C
C
C
C
T
T
G
G
T
A
A
T
T
G
A
T
T
A
G
T
G
T
T
A
T
G
A
G
G
A
G
A
G
A
T
A
A
A
C
T
G
A
C
A
T
T
A
23200
T
T
C
C
A
G
A
A
C
T
C
C
A
T
T
C
T
A
C
A
T
T
A
A
A
C
T
T
C
A
C
C
A
A
C
T
T
C
A
G
T
C
C
C
C
A
C
T
G
G
23250
A
T
G
A
C
T
C
C
T
G
C
C
T
G
A
G
T
C
A
G
C
C
A
C
C
A
C
T
A
T
C
A
T
A
G
T
C
G
C
C
A
A
A
C
A
G
T
G
A
T
23300
T
T
T
C
T
A
T
T
A
T
C
A
T
T
A
T
C
T
C
T
T
A
G
T
T
T
G
T
T
T
T
A
C
T
A
A
A
A
G
G
A
A
A
A
A
C
C
T
T
C
23350
A
T
C
T
A
T
C
A
C
C
A
G
T
A
T
A
G
A
G
T
C
A
G
G
G
A
T
T
T
G
T
A
T
T
T
T
A
T
T
C
A
A
T
T
A
A
C
G
C
A
23400
T
T
A
T
T
A
T
G
T
T
T
T
A
C
C
T
T
C
A
T
A
C
T
C
T
T
A
T
T
G
T
T
C
C
T
G
A
T
T
T
G
G
T
G
G
G
A
G
A
T
23450
C
T
T
T
C
A
A
G
G
T
G
G
G
T
T
C
T
T
C
C
C
T
C
T
C
T
C
C
G
T
C
T
C
T
C
A
T
T
C
T
T
T
G
G
A
T
A
T
A
T
23500
C
T
C
C
T
C
A
T
T
C
T
T
A
T
T
T
T
A
T
T
T
T
A
T
T
T
T
A
T
T
T
T
A
T
T
T
T
A
T
T
T
T
A
T
T
T
T
A
T
T
23550 |
REPEAT
T
T
A
T
T
T
T
A
T
T
G
A
G
A
T
G
G
A
G
G
T
T
T
G
C
T
C
T
T
G
T
T
G
C
C
C
A
G
G
C
T
G
G
A
G
T
G
C
A
G
23600
T
G
G
C
A
T
G
A
T
C
T
T
G
G
C
T
C
A
C
T
G
C
A
A
C
T
T
C
C
G
G
C
T
C
C
T
G
G
G
T
T
C
A
A
G
A
G
A
T
T
23650
C
T
C
C
T
G
C
C
T
C
A
G
C
C
T
C
C
T
A
G
C
T
G
G
G
A
C
T
A
C
A
G
G
T
G
C
C
C
A
C
C
A
C
C
A
T
G
C
C
C
23700
A
G
C
T
A
A
T
T
T
T
T
T
G
T
A
T
C
T
T
A
G
T
A
A
A
G
A
C
G
G
G
G
T
T
T
C
A
T
C
A
T
A
T
T
G
G
C
C
A
G
23750
G
C
T
G
G
T
C
T
C
A
A
A
C
T
C
C
T
G
A
C
C
T
C
A
G
G
T
G
A
T
C
C
A
C
C
T
G
C
C
T
T
G
G
C
C
T
C
C
C
A
23800
A
A
A
T
G
T
A
G
G
G
A
T
T
A
C
A
G
G
C
A
T
A
A
G
C
C
A
C
C
G
T
G
C
C
C
A
G
C
C
T
C
T
T
T
T
T
G
T
A
A
23850 |
REPEAT
T
T
A
A
A
C
A
A
A
T
T
T
T
A
T
T
A
G
A
G
A
C
A
A
G
G
T
C
T
T
A
C
G
T
T
G
T
T
G
C
C
C
A
G
G
C
T
G
G
A
23900 |
REPEAT
G
T
G
C
A
G
T
G
G
C
A
T
G
A
T
C
A
T
A
G
C
T
C
A
C
T
G
C
A
G
C
C
T
C
A
A
T
C
T
C
T
T
G
G
G
C
T
C
A
A
23950
G
T
G
A
T
C
C
T
A
T
C
A
C
C
T
C
A
G
C
C
T
C
C
T
G
A
G
T
A
G
C
T
G
G
G
A
C
C
A
C
C
G
G
C
A
C
A
T
G
C
24000
C
A
C
C
A
C
T
T
C
C
A
G
C
T
A
A
C
T
T
T
T
A
A
G
T
T
T
T
T
T
G
T
A
G
A
G
A
T
A
G
G
G
T
T
T
C
A
C
T
A
24050
T
G
T
T
T
C
C
C
A
G
G
C
A
C
A
T
C
T
C
A
A
A
C
T
C
C
T
G
G
G
C
T
C
A
A
G
T
G
T
T
T
C
T
C
C
C
A
C
C
T
24100
T
G
C
C
T
C
A
T
T
C
T
T
T
G
A
A
T
A
T
T
T
G
C
T
T
G
G
C
A
C
A
G
C
G
A
G
C
A
G
T
T
C
C
A
G
A
C
T
C
A
24150 |
REPEAT
C
T
G
T
G
T
A
C
T
T
A
C
C
C
T
G
C
C
T
C
A
G
A
C
C
T
A
G
A
A
T
C
A
G
C
T
G
T
T
G
A
T
T
T
T
T
A
T
G
G
24200
A
G
G
A
G
A
T
A
T
T
T
A
C
A
A
A
A
C
C
A
A
A
A
T
C
T
A
G
G
T
G
T
T
T
A
A
A
A
T
G
C
T
C
A
T
T
G
C
T
A
24250
T
T
G
G
G
A
T
G
T
C
A
T
T
G
T
T
T
C
T
A
G
G
C
T
T
T
C
T
C
A
G
T
G
G
A
G
T
G
A
G
A
C
C
T
A
G
A
G
A
A
24300
G
A
T
A
T
G
T
A
T
G
T
G
T
A
T
A
C
G
T
C
T
A
C
A
C
A
C
A
T
A
C
G
C
A
T
A
C
A
C
A
T
A
C
A
T
G
C
A
T
A
24350
A
C
T
T
T
T
T
A
A
A
A
A
A
C
T
A
C
C
T
C
C
C
A
C
G
T
G
C
A
G
G
T
G
C
A
T
A
C
A
G
A
T
C
T
G
G
C
C
A
A
24400
A
G
C
G
G
G
C
G
G
G
A
G
A
A
G
A
G
C
T
G
G
G
G
G
A
G
C
A
G
T
G
G
T
G
A
C
C
A
T
T
C
C
C
G
C
A
G
C
A
C
24450
C
C
T
G
G
G
A
G
T
T
T
C
C
A
T
C
T
T
T
A
T
G
T
T
T
C
T
A
T
A
G
C
T
G
T
C
T
T
T
G
T
A
T
A
T
G
G
A
T
T
24500
A
A
A
A
C
C
T
A
T
G
G
C
T
T
C
T
C
A
T
T
A
A
T
T
T
C
T
C
C
A
A
T
T
C
T
C
A
T
C
T
G
A
A
C
C
C
T
C
A
A
24550
G
A
T
T
C
T
G
T
C
T
A
T
A
T
T
T
C
C
A
T
G
T
T
A
G
T
A
A
A
A
T
T
T
C
A
A
A
A
A
G
T
G
A
C
A
A
A
T
C
T
24600
A
G
C
T
C
T
A
A
T
T
G
G
C
T
A
G
A
G
A
G
G
G
T
G
G
G
A
G
A
T
T
G
T
T
T
A
T
A
T
T
A
T
G
G
A
A
T
A
A
G
24650
A
A
A
A
T
C
A
G
C
A
A
G
T
A
C
A
T
T
A
A
G
G
A
T
G
T
A
C
G
T
T
A
A
G
G
A
T
A
T
A
C
T
T
C
C
T
A
A
T
T
24700
T
T
C
C
T
A
T
T
C
C
A
T
A
A
T
A
T
A
A
A
C
A
A
T
C
T
C
C
C
C
A
C
C
C
T
C
C
A
G
C
T
A
T
C
T
C
T
T
C
T
24750
C
A
A
C
G
T
T
T
T
T
T
A
A
A
A
G
G
T
G
A
A
A
A
C
A
T
T
T
T
T
C
C
T
T
G
T
C
T
T
T
T
T
A
G
A
A
G
T
A
A
24800
T
C
C
C
A
T
T
T
A
T
A
A
A
A
A
T
G
C
A
G
A
A
A
T
T
T
A
T
T
T
A
T
T
C
A
A
C
A
A
A
T
T
T
T
G
A
A
T
G
C
24850 |
REPEAT
C
T
G
C
T
A
G
T
G
C
A
G
G
A
C
A
T
T
G
T
G
C
A
A
G
A
T
G
C
T
A
G
T
G
A
C
A
C
A
G
G
T
A
A
A
T
C
C
T
C
24900
A
G
T
T
C
A
G
G
G
A
A
G
C
C
T
T
A
A
A
G
C
C
T
A
G
T
G
G
G
G
G
A
T
T
C
A
G
A
A
C
A
C
A
C
T
T
T
C
A
C
24950
G
C
T
G
A
T
A
A
A
A
G
G
A
T
T
G
A
T
T
A
G
A
A
G
A
C
C
C
A
A
T
G
G
G
A
G
C
C
C
C
A
A
C
C
C
T
A
A
A
T
25000
T
G
G
A
G
G
G
C
C
C
G
G
G
C
G
T
G
G
T
G
A
T
T
G
A
G
A
A
A
G
T
G
A
A
G
A
T
T
T
T
G
T
G
T
G
T
G
T
A
G
25050
G
G
A
T
G
G
G
A
G
G
G
T
G
G
G
A
G
G
G
A
G
G
T
G
A
G
C
A
T
T
G
A
C
C
T
C
T
C
T
T
G
T
C
C
A
T
A
A
A
C
25100
A
A
A
A
C
A
A
G
A
C
C
A
A
G
G
G
A
T
T
A
A
T
C
A
T
T
A
T
C
C
A
C
T
A
A
A
A
T
G
T
A
A
T
A
G
A
G
G
T
G
25150
A
C
A
G
G
A
A
A
T
T
T
T
G
G
G
G
T
A
A
A
T
T
T
T
A
T
T
C
C
C
T
G
T
G
T
T
C
C
A
G
G
T
T
C
A
T
G
T
T
C
25200
A
G
T
G
G
T
T
T
A
C
A
A
C
A
A
C
T
G
T
G
C
T
G
T
A
T
G
T
C
A
T
G
G
G
C
A
G
G
A
G
G
G
T
G
T
G
A
G
A
G
25250
G
T
G
G
T
A
G
C
A
A
T
G
T
G
G
C
A
T
G
C
T
G
T
T
C
T
T
G
T
T
G
A
C
A
G
A
C
T
T
T
T
A
T
A
G
T
G
A
G
G
25300
G
A
C
A
C
T
G
A
C
C
T
G
C
A
T
G
C
A
A
A
T
G
C
T
G
T
A
A
A
G
C
A
A
T
A
A
A
T
A
A
G
G
G
T
G
G
G
G
A
A
25350
T
G
C
A
G
T
T
T
C
A
G
G
G
A
T
G
A
T
A
G
A
A
G
G
G
T
G
G
A
G
G
G
T
G
G
G
G
T
G
G
G
C
A
G
G
C
C
A
G
T
25400
G
A
A
T
T
G
T
A
G
A
C
C
A
T
A
G
A
C
T
A
G
A
A
C
A
G
A
G
G
T
C
A
G
C
A
G
G
C
T
G
T
T
T
C
C
A
T
A
A
A
25450 |
REPEAT
G
G
G
C
A
G
A
T
A
G
T
A
T
T
A
A
T
A
A
A
C
A
T
T
T
T
C
A
G
C
T
T
T
G
T
G
G
G
C
C
A
T
G
C
G
T
C
T
G
T
25500
G
T
T
G
C
A
G
C
T
A
C
T
C
A
G
C
T
G
T
G
G
T
G
T
A
G
C
A
T
G
A
A
A
G
C
A
G
C
C
C
T
A
G
G
T
A
A
T
A
T
25550
G
T
A
A
G
G
G
A
A
T
G
A
G
C
A
C
G
G
C
C
C
T
G
T
T
C
C
A
A
C
A
A
C
C
C
T
T
T
G
T
C
T
A
A
G
A
A
A
A
C
25600
T
G
C
T
G
A
T
C
C
C
T
G
G
A
C
T
A
G
A
A
T
G
T
A
A
A
C
T
C
C
A
C
A
A
G
G
G
C
T
C
A
G
A
C
T
T
T
G
T
T
25650 |
REPEAT
T
T
T
C
G
T
T
T
G
T
T
T
G
T
T
T
G
T
T
T
T
G
T
T
C
T
C
A
A
C
T
C
T
C
C
C
A
T
G
C
C
C
T
A
G
A
A
G
A
A
25700
T
A
T
C
T
T
G
T
A
T
G
T
A
C
A
C
A
G
T
A
A
A
T
A
C
T
T
G
A
T
C
A
T
T
G
T
G
T
T
G
A
G
T
G
G
A
T
G
G
A
25750
G
T
T
G
G
A
A
T
T
A
G
C
C
A
C
T
G
C
T
C
C
A
A
A
T
G
G
A
A
A
C
T
C
T
T
G
G
C
A
T
T
T
A
T
G
A
C
T
G
G
25800
A
C
A
T
T
G
T
T
G
T
T
G
T
T
T
T
C
T
G
T
A
A
T
G
C
C
A
G
G
G
T
T
T
C
A
T
C
C
C
A
A
A
G
T
A
G
T
A
A
G
25850
C
C
A
A
G
C
T
C
T
T
T
G
T
C
T
T
A
G
A
A
C
A
T
T
C
A
T
G
T
T
G
A
G
G
T
T
T
G
G
G
T
T
A
A
T
C
A
T
T
T
25900
A
G
G
A
T
T
G
C
T
T
G
G
T
C
T
T
T
A
T
T
T
G
A
G
T
A
G
G
T
A
T
T
T
T
A
G
A
A
A
C
C
T
G
G
A
A
A
G
C
T
25950
T
T
T
C
T
G
A
C
A
G
T
G
G
A
G
C
C
T
T
A
G
T
G
A
A
T
A
A
C
A
A
G
C
T
T
A
T
G
G
T
G
A
T
T
T
T
A
G
A
G
26000
G
C
A
G
T
T
A
T
T
A
G
G
G
A
C
C
T
G
T
T
T
A
T
A
A
A
G
A
A
G
A
T
G
C
A
T
C
A
A
G
A
G
C
T
A
T
A
G
A
T
26050
A
A
A
T
G
C
A
C
C
T
T
G
A
A
A
A
T
T
T
G
C
C
C
A
A
T
C
A
T
T
A
G
T
A
T
G
T
T
G
T
T
T
T
A
C
A
C
A
T
T
26100
T
A
G
A
G
G
G
A
A
G
A
G
T
C
C
A
C
T
G
A
A
A
G
A
G
T
A
A
G
A
G
A
T
T
T
T
T
C
T
G
T
T
A
G
A
T
C
T
T
G
26150
C
T
C
C
T
G
G
T
T
T
A
C
C
T
A
A
C
T
C
C
C
A
T
T
G
T
C
T
T
T
G
T
G
C
A
G
C
G
T
T
T
C
A
C
T
G
A
G
A
G
26200
A
T
A
C
C
C
C
A
G
T
T
A
A
T
G
A
G
C
A
A
A
G
T
G
A
A
A
G
C
T
A
C
A
T
T
T
C
A
C
T
C
T
T
G
T
A
C
C
C
A
26250
C
C
A
G
C
C
A
T
T
G
T
A
C
A
A
T
T
G
T
G
A
T
A
G
T
T
C
A
A
G
T
A
C
A
A
C
A
G
G
C
A
G
T
A
A
A
T
G
C
T
26300
C
A
G
G
G
A
G
T
C
T
T
G
G
G
T
T
T
A
A
G
C
A
C
T
G
T
G
G
T
G
C
A
G
T
T
G
C
T
T
A
T
C
A
C
T
C
A
T
A
A
26350
T
T
G
T
A
T
A
G
G
A
T
C
A
T
A
G
G
A
T
T
G
G
C
C
T
C
T
G
T
G
C
T
A
A
T
C
A
T
T
A
T
T
T
G
A
G
A
A
T
G
26400
A
A
A
T
A
G
T
C
T
T
T
G
G
C
T
T
T
G
A
C
C
T
T
C
C
A
T
T
T
G
G
A
A
T
A
G
A
T
A
T
T
A
C
T
T
T
C
T
C
T
26450
G
T
G
G
A
A
T
A
T
A
T
T
G
T
A
A
C
T
T
A
C
T
T
A
T
C
A
A
T
T
C
T
A
A
G
G
A
G
A
G
A
A
T
G
G
G
C
A
T
A
26500
G
A
T
A
C
C
T
G
T
G
T
T
T
T
G
A
A
A
G
G
A
A
C
A
A
G
C
C
A
G
G
C
C
C
C
A
C
C
C
T
G
A
A
G
T
C
T
C
C
T
26550 |
REPEAT
T
T
C
T
T
C
T
T
C
T
T
C
T
T
T
T
T
T
T
T
T
T
T
C
T
G
A
G
A
C
G
G
A
G
T
C
T
T
G
C
T
C
T
G
T
T
G
C
C
C
26600
A
G
G
C
T
G
G
A
G
T
A
C
A
A
T
G
A
C
G
T
G
A
T
C
T
C
G
G
C
T
C
A
C
T
G
C
A
A
C
C
T
C
C
A
C
C
T
C
C
T
26650
G
G
G
T
T
C
A
A
G
T
G
A
T
T
C
T
C
C
T
G
C
C
T
C
A
G
C
C
T
C
C
C
G
A
G
T
A
G
C
T
G
G
G
A
T
T
G
C
A
G
26700
G
C
A
C
C
C
A
C
C
A
C
C
G
T
G
T
C
T
G
G
C
T
A
A
T
T
T
T
T
G
T
A
T
T
T
T
T
A
G
T
A
G
A
G
A
C
G
G
G
G
26750
T
T
T
T
G
C
C
A
T
G
T
T
G
G
C
C
A
G
G
C
T
G
G
T
C
T
A
G
A
A
C
T
C
C
T
G
A
C
C
T
C
A
A
G
T
G
A
T
C
C
26800
A
C
C
C
G
C
C
T
C
G
G
C
T
T
C
C
C
G
A
A
G
T
G
C
T
G
G
G
A
T
T
A
C
A
G
G
C
A
T
G
A
G
C
C
A
C
C
A
C
A
26850
C
C
C
G
G
C
C
A
A
A
T
T
C
T
C
C
T
T
T
C
T
C
C
A
G
T
T
C
C
T
T
C
A
C
T
T
A
T
C
A
T
T
C
T
A
C
T
T
G
C
26900
T
A
T
C
T
T
T
A
G
G
A
G
A
A
A
A
T
C
A
A
A
C
TATTTGCT GTCTTCTTGG GTCTCAGCAC
26950
AGTCAACACT GCCATAATTT TTTCCACCTT CCTTCTCTAT CTGAATATTC
27000
ACTACCCTCA GACATCCACT TTGTTTGAAA CGTGCTTATG TATGTACCAC
27050
GTCTTCA
T
AT TCTTAAAGGA TGACCCTACC AAAGTGATGT CTTCTCCTTC
27100 |
var(27058):[C:0.05]
TAAACTTGGA ATTTTCCAGT GTATTTATCT GACTCTTAAC AAGGAAGAAA
27150
ATGATATATC TTGAGGATAT ATCTTTTACT TTTCTAAATG GATTAAGGCT
27200
TTTTTTTTCT TT
C
GGTCATG TTTTCTTTTT ATCCTGAAGT GCTTTATCCC
27250 |
var(27213):[T:0.03]
AGCCTCGATT TCTACTTAGA TGTTTCTTGG GCTGATTAGA TTTTAGCAGT
27300
GAGAATACTT CTACCGGTAT TCCACAAATT AGCGACTTAT TAATTGTGTA
27350
GAATTTGACT AGGTAGCAAA TGTGACCACT TGAAGATACA GT
A
CTGATCA
27400 |
var(27393):[G:0.17]
TCAAACAGTA CTCAGAACA
C
GCCATGTATT TCGTTTCACA CTGTGTTAAG
27450 |
var(27420):[T:0.01]
AGCAGTAAGT GTAACGGAGA TGTTTCACAA GAATCTGTTA GTTATTTCAA
27500
GGAACGTTAA ATGTTGAATG TCATTTTCCA GAAAATATAA ATGGGTTAGA
27550
GAATAAGTGA AAGGAATTTA GAGGAATCTA TGCCATTTTT CTTGTAGGAC
27600
TTGACCAGTG ATTAACATCC ATTATATATT ACACATCAAA TCAAC
A
ATCT
27650 |
var(27646):[G:0.01]
T
T
T
T
T
T
T
T
T
T
T
C
T
T
T
A
A
G
T
A
G
A
G
A
C
A
G
T
G
T
C
T
C
C
C
T
A
T
G
T
T
G
C
C
C
A
G
G
C
T
27700 |
REPEAT
G
G
T
C
T
C
A
A
A
C
T
C
C
T
G
G
C
C
T
C
A
G
G
C
A
A
T
C
C
T
G
C
T
T
T
G
G
T
C
T
C
C
C
A
G
A
G
T
G
C
27750 |
var(27717):[G:0.01]
T
G
G
G
A
T
T
A
C
A
G
G
C
C
T
G
A
G
C
C
A
C
C
A
T
G
C
A
T
G
A
C
C
TGTTTTG TTTGTTTGTT
27800
TTCTTTAAGA GTTGGTTTGT GCTTGTGTTC TATTTGTAAT TTCATCAACC
27850
TTCATTGAGT ATATTCAGTG CCTACCCTAA ATTAATAGAA CCTGACTTAA
27900
AATGGAATAG TAAATCAGTC TGTTTTTGTG TTTACAG
T
G
G
G
A
T
C
A
T
G
A
A
A
27950 | Exon 3
G I M K 72
C
C
T
G
G
T
C
T
C
A
A
C
G
C
C
A
T
C
C
T
G
G
G
A
C
C
C
A
C
A
G
G
T
G
G
A
G
G
C
A
A
A
T
C
T
T
C
GTG
28000
P G L N A I L G P T G G G K S S 88
AGTA
T
A
A
GAG AGTATAAGTA AGCGTTTTCT GTGCACTTTT AATGTGCTTT
28050 |
var(28005):[C:0.01]
|
var(28007):[G:0.02]
TAAAAGCCAC TTTTTTTTGT GTGCG
A
G
C
A
G
G
T
A
T
T
T
A
T
T
G
A
G
C
A
T
T
T
G
C
A
28100 |
REPEAT
A
C
G
C
A
T
G
T
C
A
G
G
T
C
T
G
G
T
T
C
T
A
G
G
T
G
C
T
G
T
G
G
A
T
A
A
C
T
G
T
A
G
T
TGCGTGG
28150
TTTTTTCCCA AAGACCAGGT AGTCTTATTA GGTTAGCTTT ACTAATAGGA
28200
TTTGATAAGG TGATTGACAT GTAGCAGTTG ACCATGTTAT CAGCTAATAG
28250
GGAGGAAAAA GAATGGGAGA ATATTAAAAG TAGGGAAAGG AAGCAGAAGA
28300
TGTAAGTAAA GGCATGAGTC TTAGATAAAA GAGCACATTG CCTGTGTTAG
28350
TACCTCCAAG GTCAGACAGC TGGAAGGGCC ATTTGGGAGA TCTGTACTTG
28400
ATCAGCCAAT GGTGTCTTGC TTTATGTTTT GGGGCTTTAT TGTAATGTAC
28450
AATGAAAAGA GAAAGGTGAG AATTTTTAAA AGCATAATTT TAGTTAAACC
28500
ATAGAATTTC TTGACCAGTT AATTTTCTAA CTAAAGTAGA ATTTGGATTC
28550
AAAGTAGCCA TGAGATATAT AGCATGTGTT GGA
G
GGAAAA AAACCCCACA
28600 |
var(28584):[A:0.01]
ACATATATAT TCTCTTATAG GTTATTAGAC CCACAACATA TATGTCCTCT
28650
TATAG
G
T
T
A
T
T
A
G
A
T
G
T
C
T
T
A
G
C
T
G
C
A
A
G
G
A
A
A
G
A
T
C
C
A
A
G
T
G
G
A
T
T
A
T
C
28700 | Exon 4
L L D V L A A R K D P S G L S 103
T
G
G
A
G
A
T
G
T
T
C
T
G
A
T
A
A
A
T
G
G
A
G
C
A
C
C
G
C
G
A
C
C
T
G
C
C
A
A
T
T
T
C
A
A
A
T
G
T
A
28750
G D V L I N G A P R P A N F K C 119
A
T
T
C
A
G
G
T
T
A
C
G
T
G
G
T
A
C
A
A
GTAAGTATTA GTGGGTTTGC ATTTTCTGTT
28800 |
var(28761):[T:0.09]
N S G Y V V Q 126
TCCTCTGTTT CTATATGGGT AAGTGCTTTG GCTGATAGTT CAATGTGCTT
28850
CCAGTTGATT ATGTGACATG GTCCTAGAAC TGACGTTCTT TACAGCAGCT
28900
TTTCTTAATT TCTCATAGAC ACTTATGTGA AAAGGCAGGG AGAATCTGGA
28950
ATATGGCCCT TGTAAGGACA GTGATACCAA TTCTAGTTTT TGTATCATTT
29000
CTAAAATGAT ACATACTACT GTTATCCTTT TTTGCCTTTC CTTCACCTTT
29050
CTTTTCCCCT AGCTTAGAAA GATATTTTGG CAAATCCTTG TATGAAGCAG
29100
TTTGGAAATG TCTGCTGGTA GTTAACATAA TTACTTGCAT TCTATTTGGG
29150
TGTACAGATA GGGGGTGAAA AATGATTATA GCAGGCTTTG CAGACATCTA
29200
TGGAGTTAAC TGTCATTTGC AGAACTGCAG GTTCATCATT AGCTAGAACT
29250
TTACCTTAGT TATGTTATCT TTGTGGATTA TGTTATGTAT ACTAAACAGT
29300
CATGGTCTTA GAAAAGACTC ATTATCATTA TGTCTCATTA AAATGCTATT
29350
TGCCTTAAG
G
A
T
G
A
T
G
T
T
G
T
G
A
T
G
G
G
C
A
C
T
C
T
G
A
C
G
G
T
G
A
G
A
G
A
A
A
A
C
T
T
29400 | Exon 5
D D V V M G T L T V R E N L 140
A
C
A
G
T
T
C
T
C
A
G
C
A
G
C
T
C
T
T
C
G
G
C
T
T
G
C
A
A
C
A
A
C
T
A
T
G
A
C
G
A
A
T
C
A
T
G
A
A
A
29450 |
var(29402):[A:0.05]
Q F S A A L R L A T T M T N H E 156
A
A
A
A
C
G
A
A
C
G
G
A
T
T
A
A
C
A
G
G
G
T
C
A
T
T
C
A
A
G
A
G
T
T
A
G
G
T
C
T
G
G
A
T
A
A
A
G
T
G
29500
K N E R I N R V I Q E L G L D K V 173
G
C
A
G
A
C
T
C
C
A
A
G
GTAATGTG GAAAAACTGA AAGCATCATG ATCAGCATAA
29550
A D S K 177
GTAGGACTTT CCCTGTGTGG ATAAAATGAC TCTGATTCAG AAGTTTCCTG
29600
TAATGTGTAT GGTCAAAAAT GGTTGCTTTC CATAACAATG AGAAAAGTGG
29650
CTTGTTACAT AATATGAACG TGGAAATTAA CCTGGAAAAA AAATCTTCAC
29700
ATTGGTTGAA TTCTGCACCT GAAGTGAGGC AATGTGGTGT TGTACGTGAA
29750
AGTGTTCATC ACCTGGCCTT TCCTTATGCT CCTCCCCCAC CTCATGGTTT
29800
AAGTCACGTC TCATTCCGTG TCTGCACTAA CTTTTCTTCT TCCTCTTTTT
29850
CTCTTCCTCC TTTTAGTCAC TCTTCCTCCA AGGGACTTTG TTCCATTGCT
29900
ATTGAGGTAT ATTTCTGGGA TTGATAAGTG ATGAGAGTCC AAGGATTCTT
29950
GCTCTGTAT
C
A
G
C
A
G
T
C
C
C
C
A
A
C
T
T
T
T
G
C
C
A
C
C
A
G
G
G
A
C
C
A
G
T
T
T
T
A
T
G
G
30000 |
REPEAT
A
A
G
A
C
A
G
T
T
T
T
T
C
T
A
T
G
G
A
C
C
A
G
G
G
T
A
G
G
G
G
G
G
A
T
G
G
T
T
T
T
G
G
G
A
T
A
A
T
T
30050 |
var(30021):[A:0.01]
C
A
A
G
T
G
C
A
T
T
A
C
A
T
T
T
A
T
T
G
T
A
C
A
C
T
T
T
A
T
T
T
C
T
A
T
T
A
T
T
A
T
T
T
C
A
T
T
G
T
30100
A
A
T
A
T
A
T
A
A
T
G
A
A
A
T
A
A
T
T
A
T
A
C
A
A
C
T
C
A
T
C
A
T
A
A
T
A
T
A
G
A
A
T
C
A
G
T
G
G
G
30150
A
G
C
C
C
T
A
A
G
C
T
T
G
T
T
T
T
C
C
T
G
C
A
A
C
T
A
G
A
T
G
G
T
C
C
C
A
T
T
T
G
G
G
G
G
T
G
A
T
G
30200 |
var(30152):[A:0.07]
G
G
A
A
A
C
G
G
T
G
A
C
A
C
A
T
C
A
T
C
A
G
G
C
A
T
T
A
G
A
T
T
C
T
C
A
T
A
A
G
G
A
A
C
A
C
A
C
A
A
30250
T
T
T
A
G
A
T
C
C
T
C
G
T
A
C
A
T
G
C
A
G
T
T
C
A
C
A
A
T
A
G
G
G
T
T
C
A
T
G
C
T
C
C
T
A
T
G
A
G
A
30300
A
T
C
T
A
A
T
G
C
C
G
C
C
A
C
T
G
A
C
C
T
G
A
C
A
G
G
T
G
G
A
G
C
T
C
A
G
G
T
G
G
T
A
A
T
G
C
A
A
G
30350
C
A
T
T
G
G
G
G
A
G
C
G
G
C
T
G
T
A
A
A
T
A
C
C
G
A
T
G
A
A
G
C
T
T
T
G
C
T
C
A
C
T
T
G
C
C
T
G
C
T
30400
G
T
G
C
A
T
C
C
T
G
G
T
T
C
C
C
C
A
G
A
A
G
T
T
G
G
G
G
A
C
C
C
C
T
G
CTCTA TATGTTTCAG
30450
TTTCCTATAA TTTGGCTTCC AAAATTATAT TTGGTCAAAT TAGGATTTAT
30500
TTCTCATTTA TGTAGTGTCT GTTTTTTTTA ATAGCCTTTC TTTTAATAGT
30550
TTTGTCTCTC ATTCCCTCCC TTCTCTGCCT CTTTTTCTTC TGC
C
A
A
A
T
G
T
30600 |
REPEAT
T
T
A
C
A
G
A
C
T
T
T
T
G
T
A
T
G
C
T
A
A
G
C
T
G
T
C
T
T
T
T
A
G
G
T
T
C
T
A
G
A
G
A
T
A
C
A
A
T
T
30650
G
T
G
G
G
C
A
A
G
A
G
A
G
A
C
A
A
A
G
T
A
A
C
T
C
C
T
C
C
T
C
T
T
G
T
G
G
GTT GGAGAGGATC
30700
GTGAAGAAAA AAATGACATG AATGAA
T
GAA CTTTACAATT GATTAATATG
30750 |
var(30727):[C:0.37]
TTTGGAAGAT TTGCTGAGAA GATATTTGAA GCTTTGGGTG AAAATGAGCT
30800
TTTTGCATTG TAATGGCTAT AGTGTAATCC CCTGTGATAT CCCTTACTTA
30850
GAAGCAATGA AGAATGAGAT GTTCTAATGG TGTATACTTC ATATTATGCT
30900
TTCTGACAGT CCTTTCTGTT CAGGGTGTTT TACTGTATTT TGTTTGGAAG
30950
AGTAACTCTG AGATGCCACC ATTCACTACT TA
T
TTCCGCT TTATGAGTGA
31000 |
var(30983):[C:0.04]
TTGGGTTTTC TTTGCTTTGG TTCTGTTTGA TTTTATCTTA CCAGTAAGGT
31050
GTTTTGTTCC ACTCTATTCT TTACCTTCAG GCAGCCATTG CCCTATGTTG
31100
CTTGTTAGGA TATCTAGGGA AAATAGACTG TGAAGGCACA GCTATTGACT
31150
TCCTAGTTTA TTTATCTAAA TAATTGAAGC AATACATTTA AAATATGTTA
31200
CTTTTTGTGA AATTTTAAAC ATAACAGAAA TGTAGAGTGA ATTGTCTGAT
31250
TACTATAGTA ATGATATGGC TATAGTATAA TTAATATAAT AATGAGACAA
31300
TTAATATCAT TTACATAGAT TTCCCAGTTA TTAACCTTAG GTATATATGG
31350
GGTCAATTTG GGGAGCCTCA TGGTAATTGA AAAGGTGTTA ATATCATATG
31400
AGAGAAAGTG AACTCTCCTA GCTGCAGAGC CCATGCTCTT A
T
T
G
T
A
A
G
T
C
31450 |
NOT SCANNED
C
A
C
C
T
G
G
A
G
G
C
T
G
G
G
A
G
G
G
G
A
G
A
G
A
G
T
G
T
T
A
G
A
A
G
A
C
T
A
A
T
A
A
T
T
A
T
A
G
T
31500
T
G
C
A
T
T
C
A
C
A
T
T
T
T
C
T
T
C
T
C
C
T
G
A
C
T
T
T
A
T
C
T
C
C
C
T
T
T
T
T
A
G
A
C
T
G
T
G
A
T
31550
T
T
C
A
C
C
A
T
G
T
C
A
C
C
T
A
T
C
T
T
T
T
A
G
T
G
T
T
C
T
G
A
A
C
T
T
C
A
A
A
C
T
A
C
A
T
A
T
T
T
31600
G
A
C
T
T
G
G
T
G
A
A
G
A
A
C
A
A
A
C
T
G
T
T
A
A
A
A
G
C
A
G
G
T
G
C
T
T
T
T
T
T
T
A
A
A
A
A
A
T
T
31650
T
T
A
T
C
T
T
T
C
A
C
T
A
A
A
G
T
T
C
T
G
G
G
A
T
A
C
A
T
G
T
G
C
A
G
A
A
C
G
T
G
C
A
G
G
T
T
T
G
T
31700 |
REPEAT
T
A
C
A
T
A
G
T
A
T
A
C
A
T
G
T
G
C
T
A
T
G
G
T
G
G
T
T
T
G
C
T
G
C
A
C
C
C
T
T
C
A
A
C
C
C
A
T
C
A
31750
T
C
T
A
C
A
T
T
C
G
G
T
A
T
T
T
C
T
C
C
T
A
A
T
G
C
T
A
T
C
C
C
A
T
C
C
C
T
A
G
C
C
C
C
T
G
A
C
A
C
31800
C
C
T
G
A
C
A
G
G
C
C
C
C
A
G
T
G
T
G
T
G
A
T
G
T
T
C
C
A
C
T
C
C
C
T
G
T
G
T
C
C
A
T
G
T
G
T
T
C
T
31850
C
A
T
T
G
T
T
C
A
A
C
T
C
C
C
A
C
T
T
A
T
G
A
G
T
G
A
G
A
A
C
A
T
G
C
A
G
T
G
T
T
T
C
G
T
T
T
T
C
T
31900
G
T
T
C
C
T
G
T
G
T
T
A
G
T
T
T
G
C
T
G
A
G
A
A
T
G
A
T
G
G
T
T
T
C
C
A
G
C
T
T
C
A
T
C
C
A
T
G
T
C
31950
C
C
T
G
C
A
A
A
G
G
A
C
A
T
G
A
A
C
T
C
A
T
T
C
T
T
T
T
T
T
A
T
G
G
C
T
G
C
A
T
A
G
T
A
T
T
C
C
A
T
32000
G
G
T
G
T
A
T
A
T
A
T
G
C
C
A
C
A
T
T
T
T
C
T
T
T
A
T
T
C
A
G
T
C
T
A
T
C
A
T
T
A
T
G
G
G
C
A
T
T
T
32050
G
G
G
T
T
G
G
T
T
C
C
A
A
G
T
C
T
T
T
G
C
T
A
T
T
G
T
G
A
A
T
A
G
T
G
C
T
G
C
A
A
T
A
A
A
T
A
C
A
T
32100
G
T
G
T
G
C
A
T
G
T
G
T
C
T
T
T
A
T
A
G
T
A
G
A
A
T
G
A
T
T
T
A
T
A
A
T
C
C
T
T
T
G
C
G
T
A
T
A
T
A
32150
C
C
C
A
G
T
A
A
T
G
G
G
A
T
T
G
C
T
G
G
G
T
C
A
A
A
T
G
G
T
A
T
T
T
C
T
G
G
T
T
C
T
A
G
A
T
C
C
T
T
32200
G
A
G
G
A
A
T
C
A
C
C
A
C
A
C
T
G
T
C
T
T
G
C
A
C
A
A
T
G
G
T
T
G
A
A
C
T
A
A
T
T
T
A
C
A
C
T
C
C
C
32250
A
T
C
A
A
C
A
G
T
G
T
A
A
A
A
G
C
A
T
T
C
T
T
A
T
T
T
C
T
C
C
A
C
A
T
C
C
T
C
T
C
C
A
G
C
A
T
C
T
G
32300
T
T
G
T
T
T
C
C
T
G
A
C
T
T
T
T
T
A
A
T
C
A
T
C
G
C
T
A
T
T
C
T
A
A
C
T
G
G
C
A
T
G
A
G
A
T
G
G
T
A
32350
T
C
T
T
A
T
T
G
T
G
G
T
T
T
T
G
A
T
T
T
G
C
A
T
T
T
C
T
C
T
A
A
T
G
A
C
C
A
G
T
G
A
T
G
A
T
G
A
A
G
32400
T
T
T
T
T
T
T
C
A
T
A
T
G
T
T
T
G
C
T
G
G
C
T
A
C
A
T
A
A
A
T
G
T
C
T
T
C
T
T
T
T
G
A
G
A
A
G
T
G
T
32450
C
T
G
T
T
C
A
T
A
T
C
C
T
T
T
G
C
C
C
A
A
T
T
T
T
T
G
A
T
G
G
G
G
T
T
G
T
G
T
T
T
T
T
C
T
C
A
T
A
A
32500
A
T
T
T
G
T
T
T
A
A
G
G
T
C
T
T
T
G
T
A
G
T
T
T
C
T
G
G
A
T
A
T
T
A
G
C
C
C
T
T
T
G
T
C
A
G
A
T
A
G
32550
A
T
T
G
C
A
A
A
A
T
T
T
T
T
C
T
C
C
C
A
T
T
C
T
G
T
A
G
G
T
T
G
C
C
T
G
T
T
C
A
C
T
C
T
G
A
A
G
A
T
32600
A
G
T
T
T
T
T
T
T
T
T
T
T
C
T
T
T
C
T
T
T
T
T
T
T
T
T
G
C
T
G
T
G
C
A
G
A
A
G
C
T
C
T
T
T
A
G
T
G
T
32650
A
A
T
T
A
G
A
T
C
C
C
A
T
T
T
G
T
C
A
A
T
T
T
T
G
G
C
T
T
T
T
G
T
T
G
C
A
A
T
T
G
C
C
T
T
C
A
G
T
G
32700
T
T
T
T
A
G
T
C
A
T
G
A
A
G
T
C
T
T
T
G
C
C
C
A
T
G
C
C
T
A
T
G
T
C
C
T
G
A
A
G
G
G
T
A
T
T
G
C
C
T
32750
A
G
G
T
T
T
T
C
T
T
C
T
G
G
G
G
T
T
T
T
T
A
C
A
G
T
T
T
T
A
G
G
T
C
T
T
A
C
A
T
T
T
A
A
G
T
C
T
T
T
32800
A
A
T
C
C
A
T
C
T
T
G
A
G
T
A
G
A
G
G
T
G
T
A
A
G
G
A
A
G
T
G
G
T
C
C
A
G
T
T
T
C
A
G
T
T
T
T
C
T
G
32850
C
A
T
A
T
G
G
C
T
A
G
C
C
A
G
T
T
T
T
C
C
C
A
G
C
A
C
C
A
T
T
T
A
T
T
A
A
A
T
A
C
A
G
A
A
T
C
C
T
T
32900
T
C
C
C
C
G
T
T
G
C
T
T
G
T
T
T
T
T
G
T
C
A
G
G
T
A
T
G
T
C
A
A
A
G
A
T
C
A
G
A
T
G
G
T
T
G
T
A
G
A
32950
T
G
T
G
T
G
G
C
A
T
T
A
T
T
T
C
T
G
A
G
G
C
C
T
C
T
G
T
T
C
T
G
T
T
C
C
A
T
T
G
G
T
C
T
A
T
A
T
A
T
33000
C
T
G
T
T
T
T
G
G
T
A
C
C
A
G
T
A
C
C
A
T
G
C
T
G
T
T
T
T
G
G
C
T
A
C
T
G
T
A
G
C
C
T
T
G
T
A
G
T
A
33050
T
A
G
T
T
T
A
A
A
G
T
C
A
G
G
T
C
A
C
G
T
G
A
T
G
C
C
T
C
C
A
G
C
T
T
T
G
T
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33100
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33150
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33200
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33250
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33300
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33350
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33400
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33450
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33500
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33550
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33600
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33650
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33700
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33750
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33800
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33850
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33900
T
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33950
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34000
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34050
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34100
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A
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34150
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34200
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34250
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34300
C
A
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A
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34350
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34400
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34450
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34500
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34550
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34600
A
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34650
A
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34700
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34750
C
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A
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T
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A
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A
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C
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A
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T
34800
T
A
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C
C
A
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A
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A
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T
A
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T
A
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34850
A
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A
A
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34900
A
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T
A
C
A
G
T
T
T
T
T
T
T
T
T
T
T
T
T
T
34950 |
REPEAT
T
T
T
T
T
T
T
T
T
T
T
T
T
T
T
G
A
G
A
C
A
G
A
G
T
C
T
T
G
C
T
C
T
G
T
T
G
C
C
C
A
G
G
C
T
G
G
A
G
T
35000
G
C
A
G
T
G
G
T
G
C
A
G
T
C
T
C
A
G
C
T
C
A
C
T
G
C
A
A
G
C
T
C
C
A
C
C
T
C
C
T
G
G
G
T
T
C
A
C
G
C
35050
C
A
T
T
C
T
T
C
T
G
C
C
T
C
A
G
C
C
T
C
C
C
A
A
G
T
A
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C
T
G
G
G
A
C
T
A
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A
G
G
C
T
T
C
C
A
C
C
A
35100
C
T
T
A
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C
C
C
G
G
C
T
A
A
T
T
T
T
T
T
G
T
A
T
T
T
T
T
A
T
T
A
G
A
G
A
T
G
G
C
A
T
T
T
C
A
C
C
A
C
35150
G
T
T
A
G
C
C
A
G
G
A
T
G
G
T
C
T
T
G
A
T
C
T
C
C
T
G
A
C
C
T
C
A
T
G
A
T
C
C
G
C
C
T
G
C
C
T
C
G
G
35200
C
C
T
C
C
C
A
A
A
G
T
G
C
T
G
G
G
A
T
T
A
C
A
G
G
C
A
T
G
A
G
C
C
A
C
C
A
C
G
C
C
C
A
G
T
C
A
T
A
G
35250 |
REPEAT
T
T
G
T
G
C
A
G
T
T
T
T
G
A
G
T
G
A
G
T
T
T
T
T
T
T
T
T
T
T
T
G
A
G
A
C
A
G
A
G
T
C
T
C
G
C
T
C
T
G
35300 |
REPEAT
T
T
G
C
C
C
A
G
G
C
T
T
G
A
A
T
G
C
A
G
T
G
G
C
G
C
G
A
T
C
T
T
G
G
C
T
C
A
C
T
G
C
A
A
G
T
T
C
A
G
35350
C
C
T
C
C
C
A
G
G
T
T
C
A
C
A
C
C
A
T
T
C
T
C
C
T
G
C
C
T
C
A
G
T
C
T
C
C
T
G
A
G
T
A
G
C
T
G
G
G
A
35400
C
T
A
C
A
G
G
T
G
C
C
C
G
C
C
A
C
C
A
C
G
C
C
C
A
G
C
T
A
A
T
T
T
T
T
T
G
T
A
T
T
T
T
T
A
G
T
A
G
A
35450
G
A
C
G
G
G
G
T
T
T
C
A
C
C
G
T
G
T
T
A
G
C
C
A
G
G
A
T
G
G
T
C
T
T
G
A
T
C
T
C
C
T
G
A
C
T
T
C
A
A
35500
G
A
T
C
C
A
C
C
T
G
C
C
T
C
A
G
C
C
T
T
C
C
G
A
A
G
T
G
C
T
G
G
G
A
T
T
A
C
A
G
G
C
A
T
G
A
G
C
C
A
35550
C
C
A
C
G
C
C
T
G
G
C
C
T
T
G
A
G
T
G
A
G
T
T
T
C
T
T
A
A
T
C
C
T
G
A
G
T
T
C
T
A
A
T
T
T
G
A
T
T
G
35600 |
REPEAT
C
A
A
T
G
T
G
G
T
C
T
G
A
C
A
G
A
C
T
G
T
T
G
G
T
T
A
T
G
A
T
T
T
C
C
G
T
T
C
T
T
T
T
G
C
A
T
G
T
G
35650
A
T
G
A
G
G
A
G
T
G
T
T
T
T
A
C
T
T
C
C
A
A
T
T
A
T
G
T
G
A
T
A
A
A
T
T
T
T
A
G
A
A
T
A
A
G
T
G
C
T
35700
G
T
G
T
G
G
T
G
C
T
G
A
G
A
A
G
A
A
T
G
T
A
T
A
T
T
C
T
A
T
T
G
C
T
T
T
G
G
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A
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A
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A
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T
T
C
35750
T
G
T
A
G
G
T
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T
C
T
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T
T
A
G
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C
A
C
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C
C
A
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A
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C
T
G
A
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T
C
A
A
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C
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A
35800
A
T
A
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C
T
T
G
T
T
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A
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T
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G
A
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A
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A
A
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A
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A
35850
A
A
A
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T
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C
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A
C
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A
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A
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T
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A
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A
A
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C
T
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C
T
T
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T
A
G
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T
35900
C
T
A
A
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G
A
C
T
T
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C
T
T
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A
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A
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C
A
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C
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G
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C
A
T
A
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A
G
35950
A
T
T
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A
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A
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A
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A
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C
T
C
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T
C
T
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T
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A
A
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T
G
A
T
C
T
C
T
T
T
A
C
C
A
T
T
A
T
G
T
36000
A
A
T
A
C
T
C
T
T
C
T
T
T
C
T
C
T
T
T
T
T
T
G
A
T
C
T
T
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G
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T
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T
A
A
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T
C
T
G
T
T
T
T
A
36050
T
C
A
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A
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A
C
T
G
G
G
A
T
T
G
C
A
A
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C
C
C
T
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C
T
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C
T
T
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C
C
A
T
T
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C
T
T
G
A
36100
C
A
G
A
T
C
T
T
C
C
T
C
C
A
T
C
T
C
T
T
T
A
T
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G
A
G
C
C
T
A
T
G
T
G
T
A
T
C
T
T
T
C
A
T
G
T
G
36150
A
G
A
T
G
G
G
T
C
T
C
C
T
G
A
A
T
A
C
A
G
C
A
C
A
C
C
G
A
T
G
G
G
T
C
T
T
G
A
C
T
C
T
T
T
A
T
C
C
A
36200
A
T
T
T
G
C
T
A
G
T
C
T
G
T
G
T
C
T
T
T
T
A
A
C
T
G
G
G
G
C
A
T
T
T
A
G
C
C
C
A
T
T
T
A
C
A
T
T
T
C
36250
A
G
G
T
T
A
A
T
A
T
T
G
T
T
A
T
G
T
G
T
G
A
A
T
T
T
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A
T
C
C
T
G
T
C
A
T
T
A
T
G
A
T
G
T
T
A
G
C
T
36300
G
G
T
T
A
T
T
T
T
G
C
C
C
A
T
T
A
A
T
T
G
A
T
G
C
A
G
T
T
T
C
T
T
C
A
T
A
G
T
G
T
T
G
A
T
G
G
T
C
T
36350
T
T
A
C
A
A
T
T
T
G
G
T
A
T
G
T
T
T
T
T
G
C
A
G
T
C
A
C
T
G
G
T
A
C
C
A
G
T
T
T
T
T
C
T
G
T
T
C
T
A
36400
T
A
T
T
T
A
G
T
G
C
T
T
C
C
T
T
G
A
G
G
A
A
C
T
C
T
T
G
A
A
A
G
G
C
A
G
G
C
C
T
G
G
T
G
G
T
G
A
C
A
36450
A
A
A
T
C
C
C
T
C
A
G
C
A
C
T
T
G
C
T
T
G
T
C
T
G
T
A
A
A
G
G
A
A
T
T
T
A
T
T
T
C
T
C
C
T
T
C
A
C
T
36500
T
A
T
G
A
A
G
C
T
T
A
G
T
T
T
G
G
C
T
G
G
A
T
A
T
G
A
A
A
T
T
C
T
G
G
G
T
G
A
A
A
A
A
T
T
C
T
T
T
T
36550
C
T
T
T
A
A
G
A
A
T
T
T
T
G
A
A
T
A
T
T
G
G
T
C
C
C
C
A
C
T
C
T
C
T
T
C
T
G
A
C
T
T
A
T
A
G
G
G
T
T
36600
T
C
T
G
C
A
G
A
G
A
G
A
T
C
T
G
C
T
G
T
T
A
G
T
C
T
G
A
T
A
G
G
C
T
T
C
C
C
T
T
T
G
T
T
G
G
T
A
A
C
36650
A
C
A
A
C
C
T
T
T
C
T
C
T
C
T
G
G
C
T
G
C
C
C
T
T
A
A
C
A
T
T
T
T
T
T
C
C
T
T
C
A
T
T
T
C
A
A
C
C
T
36700
T
C
A
T
G
A
A
T
C
T
G
A
T
G
A
T
T
A
T
G
T
G
T
C
T
T
G
G
G
G
T
T
G
C
T
C
T
T
G
A
G
G
A
G
T
A
T
C
T
T
36750
T
G
T
G
C
T
G
T
T
C
T
C
T
T
T
A
T
T
T
C
C
T
G
A
A
T
T
A
G
A
A
T
G
T
T
G
G
C
C
T
G
T
C
T
T
G
C
T
A
G
36800
G
T
T
G
G
G
G
A
A
G
T
T
C
T
T
C
T
G
G
A
T
A
A
T
A
T
C
C
T
G
A
A
G
A
A
T
G
T
T
T
T
C
C
A
A
C
T
T
G
G
36850
T
T
C
C
A
T
T
C
T
C
C
C
T
G
T
C
A
C
T
T
T
C
A
G
G
T
A
C
A
C
C
A
A
T
A
A
A
A
C
G
T
A
G
G
T
T
T
T
G
T
36900
C
C
T
T
T
C
A
C
A
T
A
G
T
C
C
C
A
T
A
T
T
T
C
T
T
G
A
A
G
G
C
T
T
T
G
T
T
T
G
T
T
C
C
T
T
T
T
C
A
T
36950
T
C
T
T
T
T
T
T
C
T
C
T
A
A
T
C
T
T
G
T
C
T
T
C
A
C
G
C
T
T
T
A
T
T
T
C
A
T
T
A
A
G
T
T
T
A
T
T
T
C
37000
A
T
T
A
A
T
C
T
C
T
T
A
T
A
T
C
C
T
T
T
C
T
T
C
C
G
C
T
T
G
A
T
T
G
A
T
T
C
A
G
C
T
A
T
T
G
A
T
A
C
37050
T
T
G
T
G
T
T
T
G
C
T
T
C
A
C
G
A
A
G
T
T
C
T
T
G
T
G
C
T
G
T
G
T
T
T
T
T
C
A
G
C
T
T
C
A
T
C
A
G
G
37100
T
C
A
T
T
T
A
T
G
T
T
C
T
T
C
T
A
T
A
A
A
C
T
G
G
T
T
A
T
T
C
T
A
A
T
T
A
G
C
A
A
T
T
C
C
T
C
T
A
T
37150
C
C
T
T
T
T
T
T
C
A
G
T
G
T
T
C
T
T
A
G
C
T
T
C
C
T
T
G
C
A
T
T
G
G
G
T
T
A
G
A
A
T
A
T
G
C
A
C
C
T
37200
T
T
A
G
C
T
T
G
G
A
G
G
A
G
T
T
T
G
T
T
A
T
T
A
C
C
C
A
C
C
T
T
C
T
G
A
A
G
C
C
T
A
C
T
T
C
T
G
T
C
37250
T
A
T
T
C
A
T
C
A
A
A
C
T
C
A
T
T
C
T
C
C
A
T
C
C
A
G
T
T
T
T
G
T
T
C
C
C
T
T
G
C
T
G
G
C
G
A
G
G
A
37300
G
C
T
G
T
G
A
T
C
C
T
T
T
G
G
A
G
G
A
G
A
A
G
A
G
G
C
A
T
T
C
T
G
C
C
T
T
T
T
T
G
C
A
C
A
G
G
T
T
T
37350
T
T
C
C
T
C
A
T
C
T
T
C
A
T
A
G
A
T
T
T
A
T
C
T
A
C
C
T
T
T
G
G
T
C
T
T
T
G
A
T
G
C
T
G
G
T
G
A
C
C
37400
T
T
T
G
G
A
T
G
G
G
G
T
T
T
T
G
G
T
G
T
G
G
A
T
T
T
C
C
T
T
T
T
T
G
T
T
G
A
T
G
T
T
G
A
T
G
C
T
A
T
37450
T
C
C
T
T
T
C
T
G
T
T
T
G
T
T
A
G
T
T
T
T
C
C
T
T
C
T
A
A
C
A
G
T
C
A
G
G
C
C
T
C
T
C
T
G
C
T
G
C
A
37500
G
G
T
C
T
G
C
T
G
G
A
G
T
T
T
G
C
T
G
C
A
G
G
T
C
C
A
C
T
C
C
A
G
A
C
C
C
T
G
T
T
T
G
C
C
T
G
G
G
T
37550
A
T
C
A
C
C
A
G
C
A
G
A
G
G
C
T
A
T
A
G
A
A
C
A
G
C
A
A
A
G
A
T
A
C
C
C
C
A
A
A
G
A
T
T
G
C
T
G
C
C
37600
T
G
T
T
T
T
T
T
T
T
C
T
C
T
G
G
A
A
G
C
T
T
T
G
T
T
C
C
C
A
G
A
G
G
G
G
C
A
C
C
C
G
C
C
A
G
A
T
G
C
37650
C
A
G
C
T
G
G
A
G
C
T
C
T
C
C
T
G
T
A
T
G
A
A
G
T
G
T
C
T
G
T
C
G
A
C
C
C
C
T
G
C
T
G
G
G
A
G
G
T
G
37700
T
C
T
C
C
C
A
A
T
C
A
G
G
A
G
G
C
A
C
A
G
G
G
G
T
C
A
A
G
G
A
C
C
C
A
T
T
T
G
A
G
G
A
G
G
C
A
A
T
C
37750
T
G
T
C
C
C
T
T
A
G
C
A
G
A
G
C
T
C
T
A
G
C
G
C
T
G
T
G
C
T
G
G
G
A
G
A
T
T
C
A
C
T
G
C
T
G
T
C
T
T
37800
C
A
A
A
G
C
C
A
G
C
A
G
G
C
A
G
G
A
A
C
G
T
T
T
A
A
G
T
C
T
G
C
T
G
A
A
G
C
T
G
T
G
C
C
C
A
C
A
G
C
37850
C
T
C
C
C
C
T
T
A
C
C
T
C
A
G
C
T
G
C
T
C
T
G
T
C
C
C
A
G
G
G
A
G
G
T
G
G
G
A
G
T
T
T
T
A
T
C
T
A
T
37900
A
T
A
C
C
C
C
T
G
A
C
T
G
G
G
G
C
T
G
C
T
G
C
C
T
T
T
C
T
T
T
C
A
G
A
G
A
T
G
C
C
C
T
G
C
A
T
A
G
A
37950
G
A
G
G
A
G
G
A
A
T
C
T
A
G
A
G
A
G
G
C
A
G
T
C
T
G
G
C
T
A
C
A
G
T
G
G
C
T
T
T
G
C
C
A
A
G
C
T
G
T
38000
G
G
T
C
G
G
C
T
C
T
A
C
C
C
A
G
T
T
C
G
A
A
T
T
T
C
C
C
A
G
A
G
G
C
T
T
T
G
T
T
T
A
C
A
C
T
G
T
G
A
38050
G
G
G
C
C
T
A
C
T
C
A
A
G
C
C
T
C
A
G
T
A
A
T
G
G
T
G
G
A
T
G
C
C
C
C
T
C
C
C
C
C
C
A
C
C
A
A
G
C
T
38100 |
var(38091):[G:0.05]
C
A
A
G
C
T
T
C
C
C
A
G
G
T
T
G
A
C
T
T
T
A
G
A
C
T
G
C
T
G
T
G
C
T
G
G
C
A
G
T
A
A
G
A
A
T
T
T
C
A
38150
A
G
C
C
A
G
T
G
G
A
T
C
T
T
A
G
C
T
T
G
C
T
G
G
G
C
T
C
T
G
T
G
G
G
G
C
T
G
G
G
A
T
C
C
G
C
T
G
A
G
38200
C
T
A
G
G
C
T
A
G
A
C
C
A
C
T
T
G
G
T
T
C
C
C
T
G
G
C
T
T
A
A
C
A
G
C
C
C
C
T
T
T
T
C
C
A
G
G
G
G
A
38250 |
var(38230):[:0.85]
|
var(38243):[A:0.15]
G
T
G
A
A
C
A
G
T
T
T
T
G
T
C
G
C
G
C
T
G
G
C
A
T
T
C
C
A
G
G
C
A
C
C
A
C
T
G
G
G
G
T
A
T
G
A
A
A
A
38300 |
var(38265):[T:0.01]
A
A
A
A
A
C
T
C
C
T
G
C
A
G
C
T
G
T
C
T
C
A
G
T
G
T
C
T
G
C
C
C
A
A
A
T
G
G
C
C
A
C
C
C
A
G
T
T
T
T
38350
G
T
G
T
T
T
G
A
A
A
C
C
C
A
G
G
G
C
C
C
T
G
G
T
G
A
T
G
T
A
G
G
C
A
C
C
T
G
C
G
G
G
A
A
T
C
T
C
C
T
38400
G
G
T
C
T
G
C
G
G
G
T
T
G
T
G
A
A
T
A
C
C
A
T
G
G
G
A
A
A
A
G
T
A
C
A
G
T
A
T
G
T
G
G
G
C
C
G
G
A
A
38450
T
A
C
A
C
C
A
T
C
C
C
T
C
G
T
G
G
C
A
C
A
G
T
C
C
C
T
C
A
C
G
G
C
T
T
C
T
C
T
T
G
G
C
T
A
G
G
G
G
A
38500
G
G
G
A
C
T
T
C
C
C
C
C
A
C
C
C
C
T
T
G
T
G
C
T
T
C
C
T
G
G
G
T
G
A
G
G
C
A
T
A
G
C
C
T
C
A
C
C
C
A
38550
AGGAGGTGCT TTGTATCAGG CTTAGTTACT GACCAGCTGT GAC
C
T
G
A
A
C
C
38600 |
REPEAT
T
A
A
G
T
T
T
A
C
T
C
A
T
C
T
G
A
T
A
A
A
A
G
A
G
A
T
A
C
C
T
A
C
T
T
T
T
T
C
T
A
C
C
A
G
G
T
A
T
C
38650
C
A
C
T
T
A
T
T
T
G
C
T
G
T
T
C
A
G
A
A
T
A
A
A
T
G
A
A
C
T
T
A
A
T
G
A
G
A
T
A
A
A
G
T
G
T
C
T
C
T
38700
T
A
C
A
G
G
A
C
T
G
G
C
A
C
A
C
G
T
T
A
G
G
A
G
C
T
C
A
C
C
A
A
A
T
G
A
T
A
A
T
G
A
C
T
G
G
T
T
G
T
38750
T
A
T
CATTGAC AATTAT
A
ATA TTTGTGATTT AG
G
T
T
G
G
A
A
C
T
C
A
G
T
T
T
A
T
C
38800 |
var(38767):[G:0.19]
| Exon 6
V G T Q F I 183
C
G
T
G
G
T
G
T
G
T
C
T
G
G
A
G
G
A
G
A
A
A
G
A
A
A
A
A
G
G
A
C
T
A
G
T
A
T
A
G
G
A
A
T
G
G
A
G
C
T
38850
R G V S G G E R K R T S I G M E L 200
T
A
T
C
A
C
T
G
A
T
C
C
T
T
C
C
A
T
C
T
T
G
T
T
C
T
T
G
G
A
T
G
A
G
C
C
T
A
C
A
A
C
T
G
G
C
T
T
A
G
38900
I T D P S I L F L D E P T T G L 216
A
C
T
C
A
A
G
C
A
C
A
G
C
A
A
A
T
G
C
T
G
T
C
C
T
T
T
T
G
C
T
C
C
T
G
A
A
A
A
G
GTAAATGCTC
38950
D S S T A N A V L L L L K R 230
TGGAAACA
T
T
A
T
T
C
T
T
T
A
G
T
T
A
A
T
A
T
C
T
T
A
T
C
A
C
T
A
C
T
A
T
G
T
C
C
C
A
G
A
T
A
39000 |
REPEAT
T
T
C
T
T
G
G
G
G
C
A
G
G
G
G
G
T
T
C
A
G
A
A
A
T
G
A
T
C
A
A
A
GTAATTTC TTCCTCTTCT
39050
GTTGGAGTGA AAGTCAGTTA ACAAATGAAA AGCATTATCA AGAAAAACAA
39100
AGCAGGTAAG AATGTAGGGA AGGATGTCTG TGATGAGGGT GTAGGGGGGT
39150
TGGGCCTGTT TTGCTGCTGT CTCTTTAGCT TCTTTACTCA ACACCAACAG
39200
ACACACACAT ACACATTTTT TCTCCCTCTC TCTGCTCTAT AACACTGAAC
39250
ATTTTGTAGT TTTCTGAGTA GACCTTTTTA TTTCACACCT TTTTCATCTT
39300
ATTCTTCCAC CTTCAGTACT TTTTCTTTTT CTTCTTAGCT TCCTCCTGTT
39350
GGGCCTTTTT TACTCTACTT ATATCATCTT CAGACTGGGT TGTGAGTCTC
39400
CCATTTTGCT TATGAGGAAT CCTTAGCATC TTCTATTTCA TATTGTACTG
39450
AAATTGTTGA CCTACTGGCC TGATCCTCTT TGAGGCAGAA TGTTTTTGTG
39500
TACACTGCTA GCATACAGTA
A
GTTCTTAGA AAATGTTAAA ATTGAAGTGA
39550 |
var(39521):[G:0.01]
CTCTTCACAT AAAATATTTT GAATAGTAAC AGTTTTGAAC AGTGATTTTG
39600
GCCCTTCTTC CACCTGTGTA TTGTTATTAT AATTATTACA AATGTT
A
T
T
A
39650 |
REPEAT
C
A
A
T
T
C
A
A
G
G
T
G
A
G
A
T
T
T
G
G
G
T
G
G
G
G
A
C
A
C
A
T
A
T
C
A
T
T
C
T
G
C
C
C
C
T
G
G
C
C
39700 |
REPEAT
C
C
T
C
C
C
T
C
C
C
A
A
A
T
C
T
C
A
T
G
T
C
C
T
C
A
C
A
T
T
T
T
A
A
A
A
C
C
A
A
T
C
A
T
G
C
C
T
T
C
39750 |
NOT SCANNED
C
C
A
A
C
A
G
T
C
T
C
C
C
A
G
A
G
T
C
T
T
A
A
C
T
C
A
T
T
T
C
A
T
C
A
T
T
A
A
C
T
C
A
A
A
A
G
T
T
C
39800
A
C
A
T
T
C
T
A
A
A
G
T
C
T
C
A
T
C
T
G
A
G
A
C
A
G
G
G
C
A
A
G
T
T
C
C
A
T
C
C
A
C
C
T
A
T
G
G
G
C
39850
C
T
G
T
A
A
A
A
T
C
A
A
A
A
G
C
A
A
G
T
T
A
G
T
A
A
C
T
T
C
C
T
A
G
A
T
A
C
A
A
T
A
G
G
A
G
T
A
C
A
39900
G
G
C
A
T
T
G
G
G
T
A
A
A
T
A
C
A
C
C
T
G
T
T
C
C
A
A
A
T
G
G
G
A
G
A
A
A
T
T
G
G
C
C
A
A
A
A
C
G
A
39950
A
G
G
G
G
C
T
A
C
A
G
G
T
C
C
C
A
C
G
C
A
A
G
T
C
C
G
A
A
A
T
C
C
A
A
A
G
G
G
G
C
A
G
T
C
A
A
A
T
C
40000
T
T
A
A
A
G
C
T
C
T
G
A
A
A
T
T
A
T
C
T
T
C
T
T
T
G
A
T
T
C
C
A
T
A
T
C
T
C
A
C
G
T
C
C
A
A
G
T
C
A
40050
C
A
C
T
G
A
T
G
C
A
A
G
A
G
G
T
G
G
G
C
T
C
C
C
A
G
G
G
C
C
T
T
G
G
G
A
G
G
C
T
C
T
G
G
C
C
T
T
G
T
40100
G
G
A
T
T
T
G
C
A
G
G
G
C
A
C
A
G
C
C
C
C
T
T
T
T
G
T
G
G
C
T
G
A
T
T
T
C
A
C
A
G
G
C
T
G
G
T
A
T
T
40150
G
A
G
T
G
T
C
T
G
T
G
G
C
T
T
T
T
C
C
A
G
A
T
G
C
A
C
A
A
T
T
C
A
A
G
C
T
G
T
T
G
G
T
G
G
A
T
C
T
A
40200
C
C
A
T
T
C
T
G
G
G
G
T
C
T
T
A
A
G
G
A
T
G
A
T
G
G
C
C
C
T
C
T
T
C
T
C
A
C
T
A
C
T
G
C
A
C
T
A
A
G
40250
C
A
G
T
G
C
C
T
C
A
G
T
G
G
G
G
G
C
C
C
T
G
T
G
T
A
G
G
G
G
C
T
C
C
C
A
C
C
C
A
A
C
A
T
T
T
C
C
C
A
40300
T
C
T
G
C
A
G
T
G
C
C
C
T
A
G
C
A
G
A
G
G
T
T
C
T
C
C
A
T
G
A
G
G
G
C
T
C
C
A
C
C
C
C
T
A
A
A
G
T
T
40350
G
A
C
T
T
T
T
G
C
C
T
G
G
A
C
A
T
C
C
A
G
G
T
A
T
T
T
C
C
A
T
A
C
A
T
C
C
T
C
T
G
A
A
A
T
C
T
A
G
G
40400
T
G
A
A
G
G
G
C
A
G
G
C
C
T
A
A
C
A
C
C
A
C
A
T
G
G
A
A
G
C
T
G
C
C
A
A
C
T
C
T
C
T
G
T
T
G
G
T
C
C
40450
C
C
T
T
T
A
A
C
C
A
T
G
G
C
T
G
A
A
A
C
A
T
A
G
G
G
T
A
C
C
A
A
G
T
C
T
C
G
A
G
A
C
T
G
T
A
C
A
A
A
40500
G
C
A
G
C
A
A
G
G
C
C
C
T
G
G
G
C
C
T
G
G
C
C
T
A
G
G
A
A
A
C
C
A
T
T
T
T
T
T
C
C
T
C
C
T
A
G
G
C
C
40550
T
C
T
G
G
G
C
C
T
G
T
G
A
T
G
G
G
A
G
G
A
G
C
T
G
C
T
G
T
A
A
A
G
A
C
G
T
C
T
G
A
C
A
T
T
C
C
C
T
G
40600
G
A
G
A
C
A
T
T
T
T
C
C
C
C
A
T
T
G
T
C
T
T
G
G
T
G
A
T
T
A
A
C
A
T
T
T
G
G
T
T
C
C
C
T
A
T
T
A
C
T
40650
T
A
T
G
C
A
A
A
T
T
T
C
T
G
T
A
G
C
A
G
G
C
T
T
G
A
A
T
T
T
C
T
C
T
T
C
A
G
A
A
A
A
T
G
G
G
T
T
T
T
40700
T
C
T
T
T
T
T
T
A
T
C
G
C
A
T
C
A
T
C
A
G
G
C
T
G
C
A
A
A
T
T
T
T
C
T
G
A
G
C
T
T
G
T
A
T
G
C
T
C
C
40750
G
C
T
T
C
C
C
T
T
T
T
A
A
A
C
A
T
A
A
G
T
T
C
C
A
A
T
T
T
C
A
A
A
C
C
A
T
A
T
C
T
T
T
G
T
G
A
A
T
G
40800
A
A
T
A
A
A
A
C
T
G
A
A
T
G
C
T
T
T
T
A
A
C
A
G
C
A
C
C
C
G
A
G
T
C
A
C
C
T
C
T
T
G
A
A
T
G
C
T
T
T
40850
G
T
T
G
C
T
T
A
G
A
A
A
T
T
T
C
T
T
C
T
A
C
C
A
G
A
T
G
C
T
C
T
A
A
A
T
C
A
T
C
T
C
T
C
T
C
A
A
G
T
40900
T
C
A
T
A
G
T
T
C
C
A
C
A
G
A
T
C
T
C
T
A
G
G
G
C
A
G
G
G
G
C
A
A
A
A
T
G
C
C
A
C
C
A
G
T
C
T
C
T
T
40950
T
G
C
T
A
A
A
A
C
A
T
A
G
C
A
A
G
A
G
T
C
A
C
T
T
T
T
A
T
T
C
C
A
G
T
T
C
C
C
A
A
C
A
A
G
T
T
C
C
T
41000
C
A
T
C
T
C
C
A
T
C
T
G
A
G
A
C
C
A
C
C
T
C
A
A
C
C
T
G
G
A
C
T
T
C
A
T
T
G
T
C
C
A
T
A
T
C
A
C
T
G
41050
T
C
A
G
C
A
T
T
T
C
A
G
C
C
A
A
A
G
C
C
A
A
T
C
A
A
C
A
A
G
T
C
T
C
T
A
G
G
A
G
G
T
T
C
C
A
A
A
C
T
41100
T
T
C
C
C
A
C
A
T
C
T
T
C
C
T
G
T
C
T
T
C
T
T
C
T
T
A
G
C
C
C
T
C
C
A
A
A
C
T
G
T
T
C
C
A
G
C
C
T
C
41150
T
G
C
C
T
G
T
T
A
C
C
C
A
G
T
T
C
C
A
A
A
G
T
G
G
C
T
T
C
C
A
G
A
T
T
T
T
T
G
G
G
T
A
T
C
T
T
A
C
A
41200
G
C
A
G
C
A
T
C
C
T
G
C
T
C
T
A
C
C
A
G
T
A
C
C
A
A
T
T
T
A
C
T
G
T
A
T
T
A
G
T
T
T
G
T
T
C
T
C
A
C
41250 |
REPEAT
A
C
T
G
C
T
A
A
T
A
A
A
G
A
C
A
T
A
C
C
T
G
A
G
G
C
T
G
G
G
T
A
A
T
T
T
A
T
A
A
G
G
G
A
A
A
G
A
A
G
41300
T
T
T
C
A
T
G
G
A
C
T
T
A
C
A
G
T
T
G
C
A
C
A
T
G
G
C
T
G
G
G
G
A
G
A
T
C
T
C
A
C
A
A
T
T
T
T
C
G
T
41350
G
G
A
A
G
G
C
A
A
A
G
A
A
G
A
A
A
A
G
G
C
A
T
G
T
T
G
T
A
C
A
T
G
G
C
A
G
C
A
G
G
C
A
A
G
A
G
A
G
C
41400
T
T
G
T
G
C
A
G
G
G
G
A
A
C
T
C
C
C
A
T
T
T
A
T
A
A
A
A
C
C
A
T
C
A
G
A
T
C
T
C
G
T
G
A
G
A
G
T
T
T
41450
T
T
C
A
G
T
A
C
C
A
C
G
A
G
A
A
C
A
G
T
A
T
G
G
G
G
G
A
A
C
T
T
C
C
C
C
C
A
T
G
A
T
T
C
A
A
T
T
A
T
41500
C
T
C
C
A
C
C
T
G
G
C
C
C
C
A
T
C
C
T
T
G
A
T
A
T
G
T
G
G
G
G
A
T
T
G
T
T
A
C
A
A
T
T
G
A
A
G
G
T
G
41550
A
G
A
T
T
T
G
G
G
T
G
G
G
C
A
C
A
C
A
G
C
C
A
A
A
C
C
T
T
A
T
C
A
A
C
C
T
G
T
A
A
G
T
C
A
T
A
A
C
T
41600
C
C
T
G
T
G
A
A
A
A
G
G
T
A
C
T
T
T
A
G
C
A
C
T
A
T
T
T
T
G
G
T
C
A
T
G
G
A
C
T
T
A
G
A
C
C
A
G
A
G
41650 |
REPEAT
A
T
T
A
A
A
T
C
C
C
A
G
C
C
T
T
G
C
C
T
C
T
T
A
C
T
A
A
C
T
G
T
G
A
T
C
C
C
T
T
G
G
C
C
A
G
T
T
G
C
41700
T
T
G
A
T
C
C
T
T
T
A
A
G
A
C
A
T
A
T
T
T
A
T
A
A
A
A
T
G
A
G
G
G
T
A
A
T
A
A
T
A
A
T
A
A
T
A
T
T
G
41750
G
A
A
C
T
G
C
C
T
C
A
T
G
A
C
A
A
T
A
T
T
G
T
G
A
A
A
A
T
T
G
A
A
A
T
G
A
A
G
T
T
A
T
C
T
C
T
A
A
A
41800
T
T
A
T
T
T
A
G
C
A
A
A
G
A
C
A
T
A
G
T
A
A
G
T
A
C
T
C
A
G
T
T
A
T
G
T
T
A
A
T
T
G
C
A
T
T
A
T
T
A
41850
GGGCAGAAGA GTGAAAACCA ATTTTTAAAG AGCCAGAAGA CCTAAATGAT
41900
AAGTCAGAAT GAGATATATG ACCATTGTTT TAATATGCAG TCCATAGT
T
A
41950 |
REPEAT
G
T
T
C
T
C
A
A
A
C
T
T
G
T
A
A
A
T
A
C
T
T
G
C
A
G
A
T
T
A
C
C
T
G
G
G
T
T
G
C
T
T
C
T
T
A
A
A
A
T
42000
A
T
G
G
A
T
T
C
C
C
T
A
G
A
C
C
T
A
C
T
G
C
C
A
G
A
G
A
T
T
C
T
A
A
T
T
C
A
A
T
G
T
C
T
G
G
G
A
A
G
42050
A
C
T
G
T
C
C
T
A
G
A
A
T
C
T
G
C
A
T
T
T
T
T
A
A
T
A
A
C
T
A
T
T
C
T
A
G
T
T
G
A
T
T
C
T
AG
A
TT
42100 |
var(42098):[G:0.14]
GTCA
A
TACAA CACACTGAAA ATTCCTATTC TGTTTTAATA AAAGCATTGA
42150 |
var(42105):[G:0.01]
ATTTAGGTTT GCTAACTATA GCTAAATAAT ATGAGATGAA AAGTTAGTAA
42200
GACAAAGTCA GGCTGAACTA GAGCAAACAA TCTAAAGGCA AGAATAGAGT
42250
ATTTTACTGA GAAATACAAG TTTCAGATAT TTAATGACTT AGTATTGTCT
42300
CACTTTTAAC TTAG
G
A
T
G
T
C
T
A
A
G
C
A
G
G
G
A
C
G
A
A
C
A
A
T
C
A
T
C
T
T
C
T
C
C
A
T
42350 | Exon 7
M S K Q G R T I I F S I 242
T
C
A
T
C
A
G
C
C
T
C
G
A
T
A
T
T
C
C
A
T
C
T
T
C
A
A
G
T
T
G
T
T
T
G
A
T
A
G
C
C
T
C
A
C
C
T
T
A
T
42400
H Q P R Y S I F K L F D S L T L 258
T
G
G
C
C
T
C
A
G
G
A
A
G
A
C
T
T
A
T
G
T
T
C
C
A
C
G
G
G
C
C
T
G
C
T
C
A
G
G
A
G
G
C
C
T
T
G
G
G
A
42450
L A S G R L M F H G P A Q E A L G 275
T
A
C
T
T
T
G
A
A
T
C
A
G
C
T
G
GTAT GGTTGACTTT TTT
A
TGCTGT AAAATGCTTC
42500 |
var(42484):[G:0.07]
Y F E S A 280
ATTAATAGAA TCCTGAAGGA GAGCAAAGGG GGTCTGCAGG AGTGCTGTTT
42550
GGTCTTTGGG TAGACATACC ATGAGAATCT ATCACTTCAA AATGTGTTTG
42600
TTCCATTTGG TGCTAGTATT TTTCTTCATT TTTGTAGCAC CAGC
T
TGTTA
42650 |
var(42645):[C:0.05]
TTTAGGTATC TTTCTTGTCT TATTTCAATG TGCATGCATG TGTGTATTTC
42700
TACTGGGCCT ATATTCTGCT TCCTAGTTAC AGTGACCATT TCTTAAAAGC
42750
TCAGTAATTA ATATGTTGGC CTTATAGCCA TTTATTCTGT CACTTGAACA
42800
TTTTTGGGAA GGCCTAATAT GATTGTCTTC TTGACCATAT AACAGATGAG
42850
GCCTTAAAAT TTTTTCCCCT TGCACATGTT GGTCTGCCTT GATGAGCACT
42900
CATGGAAATG CTACTTAA
T
T
T
T
G
T
T
T
A
T
T
T
T
T
A
T
T
T
T
T
G
A
G
A
T
G
G
A
G
T
C
T
42950 |
REPEAT
T
G
C
T
C
T
A
T
T
G
C
C
C
A
G
G
C
T
G
G
A
G
T
G
C
A
G
T
G
A
C
G
T
G
A
T
C
T
T
G
G
C
T
C
A
C
T
G
C
A
43000
A
G
C
T
C
T
G
C
C
T
C
T
C
G
G
G
T
T
C
A
C
A
C
C
A
T
T
C
T
C
C
T
G
C
C
T
C
A
G
C
C
T
C
C
T
G
A
G
T
A
43050
G
C
T
G
G
G
A
C
T
G
C
A
G
G
C
G
C
C
C
A
C
A
A
C
C
A
T
G
C
C
C
G
G
C
T
A
A
T
T
T
T
T
T
T
G
T
A
T
T
T
43100
T
T
T
T
A
G
T
A
G
A
G
A
C
A
G
G
G
T
T
T
C
A
C
C
C
T
G
T
T
A
G
C
C
A
G
G
A
G
G
A
T
G
G
T
C
T
T
G
A
T
43150
C
T
C
C
T
G
A
C
C
T
T
G
T
G
A
T
C
T
G
C
C
A
C
C
T
C
G
G
C
C
T
C
C
C
A
A
C
G
T
G
C
T
G
G
G
A
T
T
A
T
43200
A
G
G
T
G
T
G
A
G
C
C
A
C
T
G
C
A
C
C
C
A
G
C
AAATTTT ATTTAAGG
T
T
T
T
T
T
T
T
T
T
T
T
43250 |
REPEAT
C
T
T
T
T
G
A
G
A
T
A
G
G
A
T
C
T
C
A
C
T
G
T
G
T
C
A
C
C
C
A
G
G
C
T
G
G
A
G
T
G
C
A
G
T
G
G
C
A
C
43300
A
A
T
C
T
T
G
A
C
T
C
A
C
T
G
C
A
G
C
C
T
C
A
A
C
C
C
C
C
C
G
C
G
C
T
C
A
A
G
C
C
A
T
C
C
T
C
C
C
A
43350
C
C
T
C
A
C
C
C
A
A
G
C
A
G
C
T
G
G
G
A
C
T
A
T
A
G
A
C
A
C
A
T
G
C
C
A
C
C
A
T
G
G
C
T
A
T
C
T
A
A
43400
T
T
T
T
T
G
T
A
T
T
T
T
T
T
G
T
A
G
A
G
T
C
G
G
G
G
T
C
T
T
G
C
C
A
T
G
T
T
G
C
C
C
A
G
G
A
T
G
G
T
43450
C
T
C
A
A
A
C
T
C
C
T
G
A
G
C
T
A
A
A
G
C
A
A
T
C
T
G
C
T
G
T
G
G
C
C
T
C
C
C
A
A
A
G
T
G
T
T
G
G
G
43500 |
NOT SCANNED
A
T
T
A
C
A
G
G
T
G
T
G
A
G
C
C
A
C
T
G
T
G
A
C
C
G
G
C
A
G
A
C
A
C
T
A
C
T
T
A
A
T
T
T
T
C
T
G
G
T
43550
A
A
C
T
A
T
A
G
A
T
T
G
C
A
G
C
T
T
T
A
G
C
C
C
T
T
G
A
G
T
G
G
G
T
A
T
C
G
G
T
C
A
A
T
A
G
A
G
T
G
43600
G
T
T
A
G
T
C
C
T
A
A
A
C
C
T
G
A
C
T
T
A
G
A
T
G
G
G
C
C
A
A
A
A
T
T
T
C
T
A
A
C
A
A
T
C
T
T
G
G
A
43650
C
A
G
C
A
T
G
G
T
T
C
T
T
T
T
T
A
T
T
T
C
A
A
A
T
T
G
A
A
A
T
G
T
G
T
G
A
T
T
T
T
T
A
A
A
A
T
T
T
T
43700
A
G
A
T
A
G
A
A
A
T
G
T
G
T
G
A
T
T
T
T
T
T
G
G
C
C
G
G
G
C
G
C
G
G
T
G
G
C
T
C
A
C
G
C
C
T
G
T
A
A
43750 |
REPEAT
T
C
C
C
A
G
C
A
C
T
T
T
G
G
G
A
G
G
C
C
G
A
G
G
C
G
G
G
C
G
G
A
T
C
A
C
G
A
G
G
T
C
A
G
G
A
G
A
T
C
43800
G
A
G
A
C
C
A
T
C
C
T
G
G
C
T
A
A
C
A
C
G
G
T
G
A
A
A
C
C
C
C
G
T
C
T
C
T
A
C
T
A
A
A
A
A
T
A
C
A
A
43850
A
A
A
A
T
T
A
G
C
C
G
G
G
C
G
T
G
G
T
G
G
C
G
G
G
C
G
C
C
T
G
T
A
G
T
C
C
C
A
G
C
T
A
C
T
C
G
G
G
A
43900
G
G
C
T
G
A
G
G
C
A
G
G
T
G
A
A
T
G
G
C
G
T
G
A
A
C
C
C
G
G
G
A
G
G
C
G
G
A
G
C
T
T
G
C
A
G
T
G
A
G
43950
C
C
G
A
G
A
T
C
G
C
G
C
C
A
C
T
G
C
A
C
T
C
C
A
G
C
C
T
G
G
G
T
G
A
C
A
G
A
G
C
G
A
G
A
C
T
C
C
G
T
44000
C
T
C
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
G
A
A
A
T
G
T
G
T
44050
G
A
T
T
T
T
T
T
T
T
A
A
T
G
G
C
T
T
G
T
G
C
G
G
T
C
T
G
C
A
T
C
A
T
T
T
T
A
G
A
T
A
T
A
T
T
T
G
G
A
44100
T
A
T
G
A
T
T
A
C
A
A
A
T
G
A
T
T
C
C
C
T
A
T
G
A
T
C
C
T
A
A
A
T
A
T
A
A
T
T
T
T
A
G
A
T
A
T
T
C
A
44150
T
T
G
G
C
C
A
T
G
T
T
T
C
T
T
A
A
T
T
A
G
G
T
T
T
T
A
A
T
A
A
A
G
G
G
G
A
T
G
A
A
C
T
A
A
G
A
G
T
C
44200
A
G
A
C
T
T
C
A
G
G
C
C
A
C
G
C
T
G
A
G
T
T
C
A
G
A
T
G
A
T
C
T
C
A
T
C
A
T
C
C
A
A
A
G
C
T
G
A
A
T
44250
G
G
T
T
C
A
G
G
T
G
T
G
C
T
G
T
G
C
T
G
G
C
C
A
T
G
T
T
C
T
A
T
C
G
A
G
A
A
T
A
C
T
G
C
T
C
A
G
G
G
44300
G
A
T
T
T
G
T
T
C
T
C
T
A
T
T
T
G
G
A
A
T
T
A
C
A
G
C
A
G
C
A
C
A
G
C
A
G
T
T
G
A
T
T
T
G
G
A
T
T
T
44350
C
T
G
A
A
T
T
A
A
T
T
A
A
T
T
A
A
T
T
A
A
T
T
T
A
C
C
T
T
T
G
A
G
A
C
A
G
A
G
T
C
T
C
A
C
T
C
T
G
T
44400 |
REPEAT
C
G
C
C
C
A
G
G
C
T
A
G
A
G
T
G
C
A
G
T
G
G
T
G
C
T
T
T
C
A
G
A
G
C
T
C
A
C
T
G
C
A
A
C
C
T
C
C
A
C
44450
C
T
C
C
C
A
G
G
T
T
C
A
A
G
C
A
A
T
T
C
T
T
G
T
G
C
C
T
C
A
G
C
C
T
C
C
T
T
A
G
T
A
G
C
T
G
G
G
A
T
44500
T
A
T
A
G
T
C
A
T
A
A
G
C
C
A
A
T
G
C
A
C
C
T
G
G
C
T
A
A
T
T
T
T
T
G
T
G
T
T
T
T
T
A
G
T
A
G
A
G
A
44550
T
G
G
G
G
T
T
T
T
G
C
C
A
T
G
T
T
G
G
C
T
A
G
G
T
T
G
G
T
C
T
G
G
A
A
G
T
C
C
T
G
G
G
C
T
C
A
A
G
T
44600
G
G
T
T
T
G
C
T
G
G
T
C
T
C
G
G
C
C
T
C
C
C
G
A
A
G
T
G
C
T
A
G
T
A
T
T
A
C
A
G
A
T
G
T
G
A
G
C
C
A
44650
T
T
G
C
A
C
C
C
A
G
C
G
C
T
G
G
A
C
C
T
C
T
G
A
A
T
T
T
A
G
T
A
T
G
T
G
G
G
G
A
A
G
T
A
G
T
C
A
T
T
44700
G
C
T
A
A
T
G
T
G
G
G
T
T
C
T
A
T
C
A
T
T
C
T
G
G
C
A
T
T
C
T
G
T
C
G
G
T
G
A
A
C
T
C
A
G
A
G
A
G
C
44750
A
G
A
A
C
A
C
A
C
C
T
G
G
G
C
T
T
T
T
G
G
A
T
T
T
T
T
T
T
C
T
T
G
G
G
T
C
T
A
T
A
T
T
T
A
G
A
T
T
T
44800
T
T
G
A
G
G
A
A
G
T
A
C
T
G
T
T
A
A
G
C
A
C
C
A
G
A
G
C
A
T
A
C
T
G
A
T
A
G
C
T
A
T
T
T
C
A
G
G
T
C
44850
T
C
A
T
G
A
A
T
T
A
T
G
A
T
A
G
G
T
A
A
G
G
A
C
C
A
A
G
C
A
C
T
A
A
T
G
C
A
A
A
A
T
G
C
C
C
T
G
C
A
44900
A
A
T
C
C
A
A
G
G
T
T
G
G
C
T
T
G
G
A
G
T
G
T
T
T
T
C
T
T
T
T
C
T
T
T
C
T
T
T
T
T
T
T
T
T
T
T
T
T
T
44950
T
T
T
G
G
C
C
C
A
G
A
G
A
C
A
A
A
G
A
A
T
T
G
C
C
G
A
A
A
T
A
T
T
G
T
G
T
G
A
T
A
G
G
C
T
G
G
G
A
A
45000 |
REPEAT
C
A
G
T
A
G
C
T
C
A
T
G
C
C
T
G
T
A
A
T
C
C
C
A
G
C
A
C
T
T
T
G
G
G
A
G
G
C
C
G
A
G
G
C
G
G
G
T
G
G
45050
A
T
C
A
C
T
T
G
A
G
G
C
C
A
G
G
A
G
T
T
C
G
A
G
A
C
C
A
G
C
C
T
G
G
C
C
G
A
C
A
T
G
G
C
A
A
A
G
C
T
45100
G
T
G
T
C
T
C
T
A
C
T
G
A
A
A
A
T
A
C
A
A
A
A
A
T
T
A
G
C
T
G
G
A
C
G
T
G
G
T
C
A
T
G
C
G
T
G
C
T
T
45150
C
T
A
A
T
C
C
C
A
G
C
T
A
C
T
T
G
G
G
A
G
G
C
T
G
A
G
G
C
A
G
G
A
G
A
A
T
C
A
C
T
T
G
A
A
C
T
C
G
G
45200
G
A
G
G
C
A
G
A
G
G
T
T
T
C
A
G
T
G
A
A
C
C
A
A
G
A
T
T
G
C
C
C
C
A
C
C
A
C
A
T
T
C
C
A
G
C
C
T
G
G
45250
G
T
G
A
C
A
G
A
G
G
G
A
G
A
C
C
C
T
G
T
C
T
C
A
A
A
A
T
A
A
A
T
A
A
A
T
A
A
A
T
T
ATATATATA
45300 |
var(45291):[A:0.30]
TATATATATA TATATATAGA GAGAGAGAGA GAGAGAGAGA GACTGAATAT
45350
ATAAAAAGAA AGGGTAAAAT TAC
G
TGGGAA GAAGAGAGAA AGAAAGTTAA
45400 |
var(45374):[A:0.19]
GGAAAAGTCA TTAGATTCTG TCTTCTCTAG CCTTACCTCC CTCACCCTCT
45450
GAAAGTGAGT TCTCTTTGTT TTCCAAGACC ATCAAGTTTG TGTTTTTGAG
45500
CTGCCTTCTT TCATAG
G
T
T
A
T
C
A
C
T
G
T
G
A
G
G
C
C
T
A
T
A
A
T
A
A
C
C
C
T
G
C
A
G
A
45550 | Exon 8
G Y H C E A Y N N P A D 292
C
T
T
C
T
T
C
T
T
G
G
A
C
A
T
C
A
T
T
A
A
T
G
G
A
G
A
T
T
C
C
A
C
T
G
C
T
G
T
G
G
C
A
T
T
A
A
A
C
A
45600 |
var(45561):[C:0.01]
F F L D I I N G D S T A V A L N 308
G
A
G
A
A
G
A
A
G
A
C
T
T
T
A
A
A
G
GT ATATGAATCT GTTACAGTCC CAGATTTTTG
45650
R E E D F K 314
CCTAATTGAA TTGGCTGAAG TTTAGCAATG TGGTGGCTAA TTAAAATGTG
45700
GCTTTGTGAA TTTCTGTTGA TGCAGTCTTC TGATACCAGT CAACACAAAT
45750
ATTTTGTTGT CTGTGAGTGC TGTTGGTGTT TTTGATTAAT TTATAAATGA
45800
GAATTTATAT GGTGTTGTCA GTTCCAAGAG GAGTTAACAT TTTAAAAAAT
45850
GCTCAGTGTT TATATAGTGT TTTTAAAATA AGAAACTTGG CAATATATGC
45900
ATTTGCATAT AGTAGGAAGC AACAACC
A
G
A
T
T
T
T
T
T
T
T
T
T
T
T
T
T
T
T
T
G
A
G
45950 |
NOT SCANNED
|
REPEAT
A
A
G
G
A
A
T
C
T
A
G
C
T
C
T
T
G
T
C
A
C
C
C
A
G
G
C
T
G
G
A
G
T
G
C
A
A
T
G
G
T
G
C
T
A
T
T
T
C
G
46000
G
C
T
C
A
C
T
G
A
C
C
C
C
T
C
C
G
C
C
T
C
C
C
A
G
G
T
T
C
A
A
G
C
C
A
C
T
C
T
C
C
T
G
C
C
T
C
A
G
C
46050
T
T
A
C
T
G
A
G
C
A
A
C
T
A
G
A
A
T
T
A
C
A
A
G
C
C
T
G
T
G
C
C
A
C
C
A
G
G
C
C
C
G
G
C
T
A
A
T
T
T
46100
T
C
G
T
A
T
A
T
T
T
A
G
T
A
G
A
G
A
T
G
G
A
G
T
T
T
C
A
C
C
A
T
G
T
T
G
G
C
C
A
G
G
C
T
G
G
T
T
T
C
46150
A
A
A
C
T
C
C
T
G
A
C
C
T
C
A
A
G
T
G
A
T
C
C
T
C
C
C
G
C
C
T
T
G
G
C
C
T
C
C
C
A
A
A
G
T
G
T
T
G
G
46200
G
A
T
T
A
C
A
G
G
T
G
T
G
A
G
C
C
A
C
C
G
C
C
C
C
T
G
G
C
C
A
C
G
A
C
C
A
G
A
A
T
T
T
T
A
T
A
T
T
A
46250
A
G
A
A
T
T
A
G
A
A
C
T
A
T
A
T
G
G
T
A
AGAAGTCTAT TTTAAAAGAA TTAAGGTCAA
46300
ATAGAAAACG TCAGTTTGTT TGCTATATTC ATAAGACTAT GGCAATAGAC
46350
AGGCTATTTC TCTGTAGTTT TCTTTTTCTT TCTTTTTCTC TTTTTAAATA
46400
TACATTTTAA TTTATTACTT AC
T
T
T
A
T
T
T
A
T
T
T
T
T
A
T
A
G
A
G
A
C
A
G
G
G
T
C
T
46450 |
REPEAT
C
G
T
T
T
C
G
T
T
G
C
T
C
A
G
G
C
T
G
G
T
C
T
T
G
A
A
T
T
C
C
T
G
G
C
C
T
C
G
C
A
T
G
A
T
C
C
T
C
C
46500
T
G
C
C
T
C
T
G
C
C
C
T
G
C
A
A
A
A
T
A
C
T
G
G
G
A
T
T
A
C
A
G
G
A
G
T
G
A
G
C
C
A
C
T
G
T
G
C
C
T
46550 |
var(46529):[G:0.16]
G
G
C
C
TGTTAT ACTTTTCTAA TGACAGAGCT AATAA
T
T
T
T
T
T
A
T
T
T
C
T
A
T
T
46600 |
REPEAT
T
T
T
T
C
T
T
T
T
T
T
G
A
G
A
T
G
G
A
G
T
C
T
T
G
C
T
C
T
C
T
T
G
C
A
C
A
G
G
C
T
G
G
A
G
T
G
C
A
G
46650
T
G
G
T
G
T
G
A
T
C
T
C
A
G
C
T
C
A
C
T
G
C
A
A
C
C
T
C
C
A
C
C
T
C
C
C
T
G
G
T
T
C
A
A
G
C
G
A
T
T
46700
C
T
C
T
T
G
C
C
T
C
A
G
C
C
T
C
C
T
G
A
G
T
G
G
C
T
G
G
G
A
T
T
A
C
A
G
G
C
A
C
G
C
A
C
C
A
C
C
A
C
46750 |
var(46750):[T:0.01]
G
C
C
A
G
G
C
T
A
A
T
T
T
T
T
T
T
T
G
T
A
T
T
T
T
C
A
G
T
A
G
A
G
A
C
A
G
G
G
T
T
T
C
A
C
C
A
T
G
T
46800
T
G
G
T
C
A
G
G
C
T
G
G
T
C
T
C
G
A
A
C
T
C
C
T
G
A
C
C
T
C
G
T
A
A
T
C
C
A
C
C
C
G
C
C
T
C
A
G
C
C
46850
T
C
C
C
A
A
A
G
T
G
C
T
G
A
G
A
T
T
A
C
A
G
T
C
A
T
G
A
G
C
C
G
C
C
G
T
G
C
C
T
G
G
C
C
TATTTT
46900 |
var(46880):[G:0.18]
TTCTTTCTAA AGCTTTAGAA TGAAGGTGTT AGGGAAGCAT CCAAGAAAGG
46950
GTTCACAGAA AAAATGGGCT AAATTTGTTG TTATCTTGTT TGTGTTTCCT
47000
TTTTATCCAC TGATTGCAAA G
C
C
A
C
A
G
A
G
A
T
C
A
T
A
G
A
G
C
C
T
T
C
C
A
A
G
C
A
G
47050 | Exon 9
A T E I I E P S K Q 324
G
A
T
A
A
G
C
C
A
C
T
C
A
T
A
G
A
A
A
A
A
T
T
A
G
C
G
G
A
G
A
T
T
T
A
T
G
T
C
A
A
C
T
C
C
T
C
C
T
T
47100
D K P L I E K L A E I Y V N S S F 341
C
T
A
C
A
A
A
G
A
G
A
C
A
A
A
A
G
C
T
G
A
A
T
T
A
C
A
T
C
A
A
C
T
T
T
C
C
G
G
G
G
G
T
G
A
G
A
A
G
A
47150
Y K E T K A E L H Q L S G G E K 357
A
G
A
A
G
A
A
G
A
T
C
A
C
A
G
T
C
T
T
C
A
A
G
G
A
G
A
T
C
A
G
C
T
A
C
A
C
C
A
C
C
T
C
C
T
T
C
T
G
T
47200
K K K I T V F K E I S Y T T S F C 374
C
A
T
C
A
A
C
T
C
A
G
A
T
G
G
G
T
T
T
C
C
A
A
G
C
G
T
T
C
A
T
T
C
A
A
A
A
A
C
T
T
G
C
T
G
G
G
T
A
A
47250
H Q L R W V S K R S F K N L L G N 391
T
C
C
C
C
A
G
G
C
C
T
C
T
A
T
A
G
C
T
C
A
G
GTAACCAG CAGATTCTTT TGAAATACTC
47300
P Q A S I A Q 398
AAATGGGAAC AATGTGGTTC TGTTATCATC TGCTTCAGGA TATGTTTATC
47350
TTCTACCCAC CCTTCCAATT ATTTGTTATC TTCACTCCAC CTGGGATATA
47400
GAACCAGTCA GCAGAACAAA TAAAGGACAA TTAAGTTTTA CTTTTGGAAA
47450
GCTTCCC
T
T
T
T
T
T
T
G
A
G
A
C
A
G
A
G
T
C
T
C
A
C
T
C
T
G
T
T
G
C
C
C
A
G
G
C
T
G
G
A
G
T
G
47500 |
REPEAT
|
var(47496):[C:0.14]
T
G
G
T
G
G
C
A
T
G
A
A
C
T
C
A
G
C
T
C
A
C
T
G
C
A
G
C
C
C
T
G
A
C
C
T
C
C
C
T
G
G
G
C
T
C
A
A
G
T
47550
G
A
T
C
C
T
C
A
C
A
C
C
T
C
A
G
C
C
T
C
T
T
G
A
A
T
A
G
C
T
G
A
G
A
C
T
A
C
A
G
G
C
G
T
G
T
C
C
C
A
47600
C
C
A
C
G
T
C
C
A
G
C
T
A
A
T
T
T
T
T
G
T
G
T
T
T
T
G
T
G
T
A
G
A
G
A
T
G
G
G
G
T
T
T
C
G
C
T
G
T
G
47650
T
T
G
C
C
C
A
G
G
C
T
G
G
T
C
T
T
G
A
A
C
T
C
G
T
G
G
G
T
T
C
A
A
G
C
G
A
T
T
C
T
C
C
T
G
C
C
T
C
A
47700
G
T
C
T
C
C
C
A
G
A
G
T
G
C
T
A
G
G
A
T
T
A
C
A
G
G
T
G
T
G
A
G
C
C
A
C
C
A
C
A
T
C
T
G
G
C
C
AGG
47750
TTCTTTTTTT TAGTGGTTTC TTAGACTACC TAACTCAGAA TTTTTGTTGA
47800
TTTAGACAAG CTGTAATGAA TAATCTGAGT AGAAAAATTT TTTTTTTGGG
47850
AAATTGTGAA AGAAGTGTCA GCCAGTTTTG GGGTTTTCTG GTAGCTGTTC
47900
ACTTTTGTTC ACTG
A
T
T
C
A
T
T
C
A
A
C
T
T
G
T
T
C
T
T
A
T
A
G
G
G
C
C
T
G
T
G
C
T
G
T
G
47950 |
REPEAT
|
var(47924):[C:0.01]
C
T
T
T
A
G
G
G
A
T
G
T
G
A
A
T
T
C
A
G
T
A
G
T
G
A
A
C
A
A
A
A
T
G
G
G
C
A
A
A
A
A
T
A
A
A
A
C
T
C
48000
T
G
C
T
C
A
T
G
G
A
G
C
T
A
A
T
T
T
T
T
T
G
A
G
G
A
A
G
A
C
A
G
T
T
A
T
G
A
T
A
A
A
T
A
A
T
A
A
A
G
48050
A
A
A
T
T
A
A
A
T
A
G
A
T
A
G
C
A
T
G
T
T
A
G
A
T
G
G
T
A
G
A
A
G
A
A
A
C
T
A
T
G
G
G
G
A
A
A
G
T
T
48100 |
var(48066):[G:0.25]
T
A
A
G
C
A
G
A
G
A
A
G
G
G
G
T
G
G
A
G
A
A
A
G
G
G
G
A
G
G
A
A
G
A
G
A
G
A
G
A
A
G
T
A
G
G
G
A
G
A
48150 |
var(48123):[:0.03]
A
G
A
A
G
G
T
T
G
A
T
T
T
G
C
A
G
T
T
G
G
A
A
T
C
A
G
G
T
G
A
T
C
A
G
G
G
A
A
A
C
C
T
T
C
A
C
C
T
A
48200 |
NOT SCANNED
C
T
G
T
C
A
C
T
G
A
A
T
A
C
A
C
C
T
G
A
A
A
G
G
G
A
G
T
A
T
G
T
G
C
T
G
G
C
C
A
C
T
C
C
A
A
G
G
G
A
48250
A
G
A
G
C
C
T
G
T
G
T
G
C
A
A
A
G
T
G
C
T
G
T
T
C
C
T
T
G
T
C
A
T
T
T
A
C
C
T
T
C
C
T
T
A
G
A
C
A
G
48300
T
T
T
A
C
A
G
G
T
G
A
A
A
C
A
A
A
T
G
T
A
G
T
A
A
G
C
A
A
A
T
T
T
G
A
G
T
T
C
A
C
A
G
A
A
C
A
A
G
G
48350
C
T
A
T
T
C
A
T
T
G
T
T
A
G
A
T
T
A
A
C
T
T
T
C
T
G
T
T
A
A
T
C
A
A
A
A
T
G
A
G
A
T
A
A
T
G
T
T
T
C
48400
T
T
T
G
T
T
C
C
T
T
G
G
T
T
G
G
C
T
C
T
G
T
G
A
T
A
G
T
T
G
G
T
G
A
T
T
A
T
T
A
C
T
C
C
T
T
G
T
G
G
48450
T
T
T
T
T
G
T
T
A
T
T
C
T
T
T
T
C
T
T
T
A
C
A
C
A
T
T
T
T
T
T
T
T
T
T
T
T
T
A
G
A
G
A
C
T
G
G
G
T
C
48500 |
REPEAT
T
C
A
C
T
C
T
G
T
C
A
C
T
C
A
T
A
C
T
G
G
A
G
T
G
C
A
G
T
G
G
T
G
C
A
A
T
C
A
T
A
G
C
T
C
A
C
T
G
C
48550
A
A
C
C
C
C
A
A
A
C
T
C
T
T
G
G
C
T
C
A
A
G
C
G
A
T
C
C
T
C
A
C
A
C
T
T
C
A
G
C
C
T
C
C
C
G
A
G
T
A
48600
G
C
T
G
T
G
A
C
T
A
C
A
G
C
C
G
T
G
C
A
C
C
A
C
A
A
C
A
C
C
T
G
G
C
T
G
A
T
T
T
T
T
T
A
A
T
T
T
T
T
48650
T
G
T
A
G
A
A
A
C
A
G
G
G
T
C
T
C
A
C
T
A
T
G
T
T
G
T
C
C
T
G
G
T
C
T
G
G
A
T
C
T
C
C