ABCA3 Color FASTA
The longest form of insertion/deletion sites is shown in the FASTA sequence and contain a '-' as the alternate allele in the variation tag.
*Display courtesy of
GeneSNPs
CTGTCAGAGG CCACCGCGCC CT
C
GCTCGGC TACCGCCGCT GCGCGCCCCC
50 |
var(23):[T:0.01]
TGCTGGACAT AGGCGCGGGC ACAGAGCAGT GCGCAAGCAC GGGCTGCCGC
100
GCGGCCGGGT GCGAACCGCG TACTCGCAGG GTGGCTGACT GCGCACGCGC
150
AAGTCAGAGC GCCCTCTGCC GGGCATGGGC GACATGCAGG GGGCACCGCG
200
CAGGCGCGGG GTTGGGCTGG CCGGAGCGGC CGAGGCGGCC GGGGGTGGAC
250
CGGGCACCTG CAGGGGCGGC CGACTGCGCA CGCGCCATCC GCGGCGCCCC
300
CTGCAGGAGC CGGAG
C
GGCC GCTGCGTCCG CCAGTAGCGG GTTGCAGGCG
350 |
var(316):[G:0.03]
CACCC
T
CCCC TCCAGGGCGG CCACGCAGCT GTCAGTGCCG CCGCCACTGC
400 |
var(356):[A:0.05]
GAGGCTGGAG CGGAGCCCGG GTGGCCGAGG GAGGGGACCC CGCGAGAGGG
450
CCGCGCGCCG GCCGC
C
GCCG CCCCGGCGCC CAGGCTCGGT GAGTGC
C
GCC
500 |
var(466):[A:0.03]
|
var(497):[A:0.02]
GGGACCCGCC GCTCGCGCGC TCGTTCCC
G
G GGCTTGCGGT CCCCACCCGG
550 |
var(529):[A:0.01]
GTCCGCCCTT CCCACCCTCG CCGGCCAGCT CGGGCCTCGG GCCCCCCCCA
600
GCTCCGGCCT GGCCTGCGGG CCCCTCCCGC GACCCCGCAT CCCCTCCGGC
650
CGCGCCCGCG CCCGCCCCTC CTG
C
CGCGGC CTCGGCTCCG GGCGCTCCCT
700 |
var(674):[T:0.01]
GCAGGTGCCG CTCCCTCAGC GTCGGCTCCC ATCCGAGCCT TGGGCGTGTC
750
CCGCACTGCG GGCAGTGCCT GAGCCCGCGC CGCGCGGGGA AGCTCGACCC
800
TGCGGAGACT CGGCACGGCC CGGGCCCTCT GTGTGCGCCC AGAAGGTGGA
850
TATGTAGCGA CCGACAGCCC CGGCCCCGAG GGATGCAGGC GTCCGCCGCG
900
CACTTGCGGA GATGGCGCCG CTTTCCGGCC GCAGGGA
T
G
C
C
G
G
G
C
G
C
G
C
G
950 |
NOT SCANNED
G
T
G
G
C
A
A
A
G
C
C
G
C
C
C
G
G
G
T
T
G
G
A
T
T
C
C
G
C
C
T
G
C
T
C
C
C
A
C
C
C
T
C
T
G
G
T
T
C
C
1000
G
A
G
G
A
G
C
C
T
C
C
A
A
A
T
C
C
G
A
A
T
C
C
A
A
G
G
C
C
C
A
C
G
G
T
C
C
G
C
G
G
C
G
G
G
C
G
T
T
T
1050
G
C
T
G
C
G
C
C
C
T
C
C
A
C
T
G
T
G
T
G
G
G
A
A
C
G
G
G
A
A
A
G
G
G
G
A
G
C
C
G
C
T
A
G
T
C
C
A
G
G
1100
C
G
G
A
G
G
G
G
C
T
T
G
T
G
G
C
A
G
T
C
G
C
C
G
G
A
G
G
C
C
G
C
G
T
T
C
T
C
G
G
C
G
C
C
C
T
C
G
G
T
1150
C
A
G
G
A
C
G
C
C
T
G
T
G
T
G
C
A
T
C
G
C
G
T
C
C
G
T
G
T
G
T
C
T
T
G
G
C
T
C
T
G
T
T
C
C
A
A
G
C
C
1200
G
G
C
T
C
C
A
C
G
C
T
T
C
A
G
A
A
G
G
G
C
C
G
G
G
A
C
G
G
C
C
T
T
A
T
G
G
T
C
A
G
G
G
G
C
G
T
G
G
G
1250
G
A
A
G
G
C
G
C
T
T
G
G
T
G
T
C
T
G
T
C
G
C
A
C
A
G
A
T
G
A
A
G
C
C
A
T
G
T
C
C
T
C
A
G
G
G
G
G
T
A
1300
A
T
T
G
C
C
G
C
T
T
G
T
T
C
T
C
C
G
G
G
T
T
A
C
G
T
C
C
T
G
G
A
C
T
G
T
G
C
A
C
T
C
C
G
G
G
A
A
G
G
1350
C
G
T
C
G
A
T
T
G
G
A
T
C
T
T
G
T
T
G
G
G
G
T
T
T
G
T
G
T
T
C
C
T
G
G
A
A
C
T
C
C
A
G
A
A
A
T
G
C
C
1400
C
G
C
T
G
A
G
T
G
A
G
T
A
G
C
C
G
A
G
A
C
C
C
C
G
C
G
A
C
A
G
C
A
T
G
G
A
G
C
C
C
A
G
G
C
A
G
G
G
A
1450
G
C
A
C
G
T
G
G
G
A
G
A
G
G
T
T
C
A
C
T
C
T
T
C
T
C
C
T
G
G
G
C
A
T
C
C
C
G
T
C
A
T
T
T
T
A
T
T
C
A
1500
G
A
T
A
G
T
C
T
G
G
G
C
G
C
T
G
C
C
T
T
T
T
G
T
A
A
A
C
T
T
G
A
A
A
A
G
A
C
T
A
A
G
A
C
T
G
T
T
T
T
1550
A
G
A
A
A
G
T
T
T
G
C
C
T
C
A
T
G
A
G
A
A
A
T
G
T
A
A
G
A
G
A
A
A
G
G
G
A
A
A
A
A
T
A
G
A
T
A
A
A
A
1600
A
T
G
G
A
T
G
T
C
A
T
G
G
G
A
A
T
C
T
C
C
C
C
C
A
C
A
C
T
T
T
C
A
T
T
T
T
T
A
A
C
T
T
C
T
T
A
G
A
T
1650
A
A
T
T
T
T
T
C
T
T
T
T
A
A
A
T
T
G
A
A
C
C
T
T
T
G
C
T
A
A
C
T
C
T
A
C
C
T
G
A
A
A
A
A
C
A
G
G
A
C
1700
G
A
C
G
T
C
T
C
T
C
C
C
T
T
C
C
T
A
A
A
G
T
G
A
C
T
T
A
C
C
ACCATTCTGA CCAGACAGGC
1750
TTTTGGAACA GGAGAGGGTA GCACGAGTTG TTTCTAAAAA GATGTTAGCC
1800
TTCCATCTGC ATGAGCCAGG CAGTCTCATG GGAGCCCATT TTGACGTAGT
1850
CTCAACTGGG AAGGCCCAGG TAAGATCCCT AGTTTGCCAT TTCTTCCCCA
1900
GCCCTGCTTC CGGAGACTGT GGAATCTATT GAGGGGAAGC ATTCTGGAAC
1950
TTTGGGGACG GCTCTGACGG GGAAGGCCTT GTGCACAATG GAAAGATGAA
2000
TTGGA
A
G
C
C
G
G
G
C
T
A
A
G
T
G
G
C
T
C
A
C
A
C
C
T
G
T
A
A
T
C
C
C
A
G
C
A
C
T
T
T
G
G
G
A
G
2050 |
REPEAT
G
C
A
G
A
G
G
C
G
G
G
C
G
G
A
T
C
A
C
T
T
G
A
G
T
T
C
A
G
G
A
G
T
T
C
G
A
G
A
C
C
A
G
C
C
T
G
G
C
C
2100
A
A
C
A
T
G
G
C
G
A
A
A
C
C
T
C
A
T
C
T
T
T
A
C
C
A
A
A
A
A
T
A
T
A
A
A
A
A
A
T
T
A
G
C
C
G
G
G
C
A
2150 |
NOT SCANNED
T
G
G
T
G
G
C
A
C
G
T
G
C
C
T
G
T
A
A
T
C
C
C
A
G
C
T
A
C
T
C
A
G
G
A
G
G
C
T
G
A
G
G
C
A
G
A
A
G
A
2200
A
T
C
G
C
T
T
G
A
A
C
A
T
A
T
T
A
G
G
T
G
G
A
G
G
T
T
A
C
A
G
T
G
A
G
C
T
G
A
G
A
T
G
G
C
A
C
C
A
C
2250
T
G
C
C
C
T
C
C
A
G
C
C
T
G
G
G
C
G
A
C
A
G
A
G
C
A
A
G
A
C
T
C
T
G
T
C
T
C
A
A
A
A
A
A
A
A
A
A
A
A
2300
A
A
A
A
A
A
A
A
A
G
A
TGAATTGGA CACAGTCCCT GCTCTTGGAG GGGTCTTAGG
2350
ATAGAGCTAA AGAGATGCTT TATTCACAAG TAACTGTGAC ATAAGACAGA
2400
ACAAGATGAG TACCACATG
A
CACATCCAGA AAAGGTGCAA CAGGTGACCA
2450 |
var(2420):[C:0.12]
GAGGTGGAGG AGAGTTGGCT CCAAGAAGAG
C
A
G
A
G
G
G
T
C
T
C
C
A
C
C
C
A
G
G
C
2500 |
REPEAT
T
T
C
C
C
G
T
T
A
C
A
A
T
C
A
C
C
T
G
G
G
A
A
G
C
C
A
G
C
C
T
G
G
G
C
C
C
A
A
A
A
C
A
G
C
C
C
A
G
A
2550
A
T
C
T
C
C
A
G
G
G
G
T
G
G
G
C
C
T
C
A
G
A
T
G
T
C
A
G
T
T
T
C
T
G
T
C
T
T
A
A
A
G
T
G
C
C
C
T
G
G
2600
A
A
A
A
T
T
C
C
A
T
T
G
T
G
C
A
G
G
C
A
G
C
C
A
A
G
A
C
A
A
A
G
A
G
C
C
C
C
T
G
A
A
A
C
A
A
G
C
T
T
2650 |
NOT SCANNED
C
A
C
A
G
A
G
G
C
C
A
T
G
G
T
A
C
T
A
G
A
A
G
T
G
G
G
C
T
G
G
G
A
A
G
T
G
A
T
G
G
G
T
A
G
G
T
A
G
A
2700
G
A
A
A
G
G
T
A
T
C
C
G
G
G
T
G
A
T
A
T
T
C
T
A
G
G
C
A
G
A
C
A
A
A
A
C
A
C
T
G
A
A
G
G
C
C
C
A
C
A
2750
T
C
T
T
G
T
G
G
G
G
A
A
G
A
G
T
G
A
G
G
C
A
T
G
T
C
A
G
G
C
C
C
T
G
T
C
C
T
G
G
G
A
G
A
G
T
T
T
T
G
2800
C
A
G
A
C
C
C
C
A
T
T
C
C
C
C
T
G
A
A
T
G
G
C
T
C
A
G
A
G
T
G
T
T
T
G
T
G
G
T
G
T
T
G
G
A
G
A
G
G
T
2850
T
T
G
G
A
G
T
C
A
A
C
A
G
G
C
A
G
A
C
A
G
G
T
G
C
C
T
T
T
G
C
G
G
G
A
G
C
C
G
T
G
T
A
A
C
G
A
G
G
T
2900
C
C
T
T
G
C
T
A
A
C
T
T
G
C
T
T
G
T
T
G
G
A
G
A
A
C
A
T
C
C
A
T
G
G
T
T
A
C
C
T
C
C
C
T
C
T
G
G
G
G
2950
A
C
T
T
T
C
C
A
T
T
G
C
C
T
C
A
T
T
A
C
C
T
C
G
T
T
T
C
C
T
G
C
A
C
C
T
A
G
G
G
A
G
G
C
A
G
A
A
C
A
3000
G
C
T
A
G
C
T
G
G
C
T
G
G
A
G
A
A
C
G
G
G
A
C
T
G
A
A
G
C
C
A
C
G
G
C
A
A
G
G
G
T
T
A
G
G
G
A
A
A
C
3050
A
G
G
C
A
G
T
A
G
C
A
G
A
G
A
T
T
T
T
G
T
G
G
A
A
G
T
C
T
G
T
C
C
C
G
A
T
A
G
C
T
C
C
C
T
T
T
G
G
A
3100
A
C
C
A
C
G
T
C
T
C
T
G
G
C
T
T
A
A
A
A
A
T
A
C
A
C
C
C
T
A
T
G
A
A
C
C
C
C
T
G
C
C
A
G
A
G
C
T
T
C
3150
A
T
T
G
T
A
A
A
C
G
C
A
G
A
G
C
C
T
G
T
G
A
T
C
C
T
A
G
G
G
A
G
G
C
A
G
C
C
G
C
C
T
C
C
A
A
C
T
C
C
3200
A
G
G
C
A
G
C
G
C
C
T
G
T
G
G
T
G
C
T
G
A
G
T
A
T
G
A
G
C
G
C
C
A
G
C
A
A
G
C
T
A
G
G
G
C
T
C
C
A
T
3250
C
A
G
G
G
C
C
T
G
C
G
A
T
G
C
C
A
G
T
G
C
C
A
C
A
G
C
C
T
C
A
A
A
C
C
A
G
C
C
T
C
C
C
C
A
G
C
T
C
T
3300
C
A
G
C
C
A
A
T
G
G
C
T
G
T
G
G
G
T
T
G
T
G
C
A
T
T
T
G
T
T
C
C
T
A
C
C
T
C
A
T
C
C
C
C
A
C
A
A
G
G
3350
G
C
C
A
C
T
G
A
G
G
T
T
A
T
A
A
A
T
T
G
G
C
C
T
T
G
G
C
C
A
G
T
G
C
A
A
G
T
G
A
T
T
C
A
C
A
T
C
T
G
3400 |
REPEAT
T
A
A
T
C
T
T
G
G
C
A
C
T
T
T
G
G
G
A
G
G
C
C
A
A
G
G
C
G
G
G
A
G
G
A
T
C
A
C
T
T
G
A
G
G
C
C
A
C
A
3450
A
G
T
T
G
G
A
A
G
A
A
C
A
G
C
C
T
G
G
G
C
A
A
C
A
T
G
G
C
A
A
G
A
T
C
C
C
A
T
C
T
C
T
A
A
A
A
A
A
A
3500
A
A
A
A
A
A
A
A
A
A
A
A
T
C
A
A
A
C
A
A
T
T
A
G
C
C
G
G
G
C
A
T
G
G
T
G
G
T
G
C
A
C
A
C
C
C
A
T
G
G
3550
T
C
C
C
A
G
C
T
A
T
T
T
G
G
G
A
G
A
C
T
G
A
G
G
T
G
G
G
A
G
G
A
T
C
A
C
T
T
G
A
G
C
C
A
G
G
A
G
G
T
3600
C
A
A
G
G
C
T
A
C
A
G
T
G
A
G
C
C
A
T
G
A
T
C
A
C
A
C
C
A
C
T
A
T
C
T
A
T
A
C
T
C
C
A
G
C
C
T
A
G
G
3650
C
A
A
A
A
G
A
G
T
G
A
G
A
C
C
C
T
G
C
A
T
G
A
A
A
A
A
A
A
A
A
A
A
A
A
G
G
C
C
T
C
A
G
A
C
T
T
T
T
T
3700
T
T
T
T
C
A
T
G
T
G
T
A
C
T
G
T
T
A
T
G
T
G
T
A
A
A
A
G
A
A
T
G
A
A
T
G
T
A
A
A
C
A
T
G
C
A
G
C
C
C
3750
A
A
T
A
T
A
T
A
T
T
A
T
G
T
G
T
T
A
T
A
A
A
T
T
A
C
A
A
T
T
A
C
T
G
T
C
C
T
G
A
T
G
T
A
T
T
A
T
G
G
3800
A
C
A
T
A
G
A
A
A
T
A
T
A
T
A
C
A
A
A
T
T
T
G
G
A
T
C
T
T
T
T
A
A
A
G
G
G
A
C
G
A
A
G
G
C
C
A
G
A
C
3850 |
REPEAT
A
G
A
C
A
T
G
G
T
G
G
C
T
C
A
C
A
C
C
T
G
T
A
T
A
C
C
C
A
G
C
A
C
T
T
T
G
G
G
A
G
G
C
T
G
A
G
A
T
G
3900
A
G
A
C
A
A
T
C
C
C
T
T
A
A
G
G
C
C
A
A
G
A
G
T
T
T
G
A
G
A
A
C
A
G
T
C
T
G
G
G
C
A
A
C
A
T
A
G
T
G
3950
A
G
A
C
C
C
T
G
T
C
T
C
T
A
C
T
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
T
A
G
C
C
A
G
G
T
A
T
G
G
T
G
G
C
G
4000
T
G
C
A
C
C
T
G
A
A
G
T
C
C
C
A
G
C
T
A
C
T
G
T
G
G
A
G
G
C
T
G
A
G
G
A
G
G
G
A
G
G
A
T
C
G
C
T
T
G
4050
A
G
C
C
T
G
G
G
A
A
T
T
C
A
A
G
A
A
T
G
C
A
G
T
G
A
G
C
T
A
T
A
A
T
G
A
T
G
C
C
A
T
T
G
C
A
C
T
G
C
4100
A
G
C
C
T
G
G
G
A
A
A
C
A
G
A
G
C
A
A
G
A
C
C
C
T
G
T
C
T
C
T
A
A
C
A
G
A
G
A
A
A
A
A
A
A
A
A
A
A
A
4150
G
G
A
T
G
A
G
A
G
G
T
G
A
A
A
T
A
A
A
C
A
T
G
A
T
T
A
A
A
T
T
T
A
T
C
C
A
A
C
A
T
A
T
G
A
A
T
G
C
T
4200
A
C
A
A
A
A
A
C
T
A
T
T
G
T
A
T
A
A
A
C
A
T
G
C
T
T
T
T
T
A
A
A
G
A
T
G
A
A
A
G
C
C
A
T
G
T
G
T
C
C
4250
A
C
A
T
C
C
C
A
T
T
T
A
T
A
A
A
C
T
C
T
C
A
T
T
G
A
A
T
C
C
T
A
A
G
T
C
C
C
A
G
C
A
T
T
T
A
A
G
A
T
4300
C
A
A
T
T
G
T
A
A
G
T
T
C
T
G
T
T
T
A
T
T
G
G
C
C
A
G
A
C
G
A
G
G
T
G
G
C
T
C
A
C
G
C
C
T
G
T
A
A
T
4350 |
REPEAT
C
C
T
A
G
C
A
C
T
T
T
G
G
G
A
G
G
C
C
G
A
G
G
T
G
G
G
T
G
G
A
T
T
G
C
T
T
G
A
G
G
T
C
A
G
G
A
G
T
T
4400
C
T
A
G
A
C
C
A
G
C
C
T
G
G
T
C
A
A
C
A
T
G
G
T
G
A
A
A
C
C
C
C
G
T
C
T
C
T
A
C
A
A
A
A
A
A
A
A
A
A
4450
A
A
A
A
A
A
A
A
A
A
A
A
A
T
T
A
G
C
T
G
G
G
C
G
T
G
G
T
G
G
C
G
G
G
C
A
C
C
T
G
T
A
A
T
T
C
C
A
G
C
4500
T
A
C
T
C
A
G
G
A
G
G
C
G
G
A
G
G
C
A
G
G
A
G
A
A
T
C
A
C
T
T
G
A
A
C
C
T
G
G
G
A
G
G
C
A
G
A
G
G
T
4550
T
G
C
A
G
T
G
A
G
C
C
G
A
G
A
T
T
G
C
A
C
C
T
T
T
G
C
A
C
T
C
C
A
G
C
C
T
G
G
G
C
A
A
C
A
A
G
A
G
T
4600
G
A
A
A
C
T
C
T
G
T
C
T
C
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
G
T
T
C
T
G
T
A
T
A
T
T
T
C
A
G
G
C
C
C
T
4650
A
G
T
T
A
T
T
A
A
C
A
G
C
A
T
T
T
A
C
A
C
A
T
T
A
A
C
A
T
G
A
T
A
C
A
G
A
G
A
A
A
G
G
C
A
C
A
G
A
C
4700
C
C
T
G
T
G
C
T
T
A
C
G
A
G
G
C
A
G
G
G
T
A
C
T
T
G
T
T
T
T
T
C
A
A
T
T
T
C
A
T
T
T
A
C
C
C
A
T
C
A
4750 |
REPEAT
T
C
T
G
A
G
G
G
C
C
C
T
T
G
A
T
G
A
A
T
T
T
G
G
G
C
T
G
G
G
T
A
T
G
T
T
C
A
G
G
G
G
C
T
A
T
C
A
G
G
4800
G
T
A
G
G
T
G
G
A
G
A
T
T
C
T
G
G
T
G
T
T
G
A
A
G
A
T
G
T
T
T
T
G
G
T
G
T
G
C
G
G
G
T
G
T
A
A
A
T
G
4850 |
REPEAT
T
T
C
A
T
A
T
A
G
A
C
A
G
T
A
C
G
C
T
T
G
T
A
G
C
A
T
C
A
T
T
G
G
G
A
A
C
G
C
A
G
T
C
A
C
G
T
A
A
T
4900
T
G
T
G
G
A
A
A
C
C
T
C
T
T
C
A
A
A
C
G
T
C
T
G
T
T
T
T
C
A
C
A
A
A
T
G
C
T
C
T
A
T
T
C
T
T
G
G
T
A
4950
C
A
G
A
T
T
C
T
T
T
T
T
G
A
A
A
A
G
C
T
G
T
A
A
C
T
C
T
C
A
T
A
T
A
C
T
G
T
C
A
C
T
T
T
T
T
C
T
T
T
5000
G
A
A
G
G
G
A
C
A
G
A
T
T
A
C
G
T
T
G
T
G
T
C
T
A
T
T
T
A
A
A
A
G
A
A
A
A
A
A
G
G
T
A
G
A
T
G
A
C
A
5050
C
A
C
T
G
C
T
G
C
A
G
T
C
A
T
T
T
G
T
C
A
T
T
A
A
A
A
A
C
G
A
A
A
A
A
A
T
G
T
C
T
C
C
G
G
A
T
T
T
G
5100
G
A
A
C
T
T
T
T
C
A
C
A
A
A
A
G
A
A
A
A
T
C
T
G
T
A
C
C
T
T
C
T
C
C
T
T
A
A
A
T
T
C
T
C
T
G
A
C
T
C
5150
T
T
T
G
A
A
A
T
A
C
T
A
A
G
C
C
A
T
G
A
A
A
T
G
A
C
C
A
G
T
A
A
A
C
C
T
C
C
A
A
G
T
C
A
C
A
C
A
A
A
5200
A
G
A
T
A
C
T
C
A
T
G
G
T
C
A
T
T
T
T
C
C
A
C
A
T
C
A
C
T
G
C
G
A
A
G
C
A
T
T
G
T
A
A
A
G
C
T
T
T
C
5250
G
C
T
A
T
T
T
A
A
G
G
G
T
C
T
T
G
A
G
T
T
T
T
T
G
T
G
G
T
T
T
G
T
T
T
G
T
T
T
G
T
T
T
T
A
A
T
T
G
A
5300
C
C
A
C
A
A
C
T
G
G
A
A
A
G
C
T
C
T
G
A
A
A
C
T
T
G
T
A
A
A
C
T
C
C
A
A
C
A
C
G
C
C
T
A
G
G
A
T
G
C
5350 |
REPEAT
T
T
A
A
A
G
T
A
G
A
C
T
T
G
T
G
G
T
G
A
G
G
G
C
C
C
A
C
C
A
T
C
A
C
T
C
C
C
C
A
C
A
T
C
A
C
A
G
G
G
5400
T
G
C
C
T
C
C
T
C
C
T
C
A
G
T
C
A
G
G
A
T
G
C
C
A
C
G
G
C
T
G
C
T
G
A
C
A
T
A
C
A
A
G
C
C
A
G
C
G
T
5450
G
A
A
C
A
C
C
A
G
G
G
T
C
T
G
T
C
C
A
A
G
T
A
T
T
A
A
A
T
G
T
C
A
G
T
A
A
A
G
C
T
G
G
C
A
G
G
G
T
G
5500 |
REPEAT
T
G
G
T
A
T
C
G
C
A
T
G
C
C
A
G
T
G
G
T
C
C
C
A
G
C
A
C
T
T
T
G
G
G
A
G
G
C
T
G
A
G
G
C
A
A
G
A
G
G
5550
A
T
C
A
T
T
T
G
A
G
C
C
C
A
G
G
A
G
T
T
T
G
A
G
A
C
C
A
G
C
C
T
G
G
G
C
A
A
C
A
T
A
G
T
G
A
G
A
C
T
5600
C
G
T
C
T
C
T
A
C
A
A
A
A
A
A
A
A
G
C
C
A
G
G
T
G
T
G
G
T
G
G
T
A
C
A
T
G
C
C
T
G
T
A
G
T
C
C
C
A
G
5650
C
T
A
C
T
T
A
G
G
A
G
G
C
T
G
A
G
G
C
A
G
G
A
G
G
A
T
C
A
C
A
C
C
A
C
T
G
C
A
T
T
C
C
A
G
C
C
G
G
G
5700
A
T
A
A
C
T
G
T
G
T
G
T
G
A
C
T
G
A
G
A
T
C
C
T
G
T
C
C
C
T
A
C
A
G
G
A
A
A
C
A
A
A
C
A
A
A
C
A
A
A
5750
C
A
A
A
C
A
A
A
T
C
A
G
T
G
A
A
G
C
C
A
T
T
T
T
T
T
T
C
A
C
A
T
T
T
T
T
A
A
A
G
A
A
A
A
A
T
A
C
T
T
5800
A
C
A
A
G
T
A
G
A
T
T
T
T
T
T
C
A
T
C
A
C
T
T
T
T
T
C
A
C
T
G
C
T
G
C
A
G
G
T
T
G
T
C
T
A
G
C
C
C
A
5850
C
C
C
C
A
T
T
T
G
G
A
G
A
C
C
A
C
T
G
G
G
A
A
G
G
G
G
T
G
A
G
G
A
C
C
A
T
A
C
T
C
T
A
T
A
A
A
T
G
T
5900
G
C
C
T
G
C
T
T
T
T
T
T
T
A
T
A
T
A
T
T
A
A
T
A
A
T
A
T
T
T
A
G
G
G
C
C
G
G
G
C
A
C
A
G
T
G
G
C
T
T
5950 |
REPEAT
A
C
A
C
C
T
G
T
A
A
T
C
C
C
A
G
C
A
C
T
T
T
G
G
G
A
G
G
C
A
G
A
G
G
C
A
G
G
C
A
G
A
T
C
A
C
T
T
G
A
6000
G
G
T
C
A
G
G
A
G
T
T
C
G
A
G
A
C
C
A
G
C
C
T
G
G
C
C
A
A
C
A
T
G
G
T
G
A
A
A
C
C
C
C
G
T
C
T
C
T
A
6050
C
T
G
A
A
A
A
T
A
C
A
A
A
A
A
T
T
A
G
C
T
G
G
G
C
G
T
G
G
T
G
G
C
G
A
G
T
G
C
C
T
G
T
A
A
T
C
C
C
A
6100
G
C
C
A
C
T
C
A
G
G
T
C
G
C
T
G
A
G
G
C
A
G
G
A
G
A
A
T
C
G
C
T
T
G
A
A
C
T
C
A
G
G
A
G
G
T
G
G
A
T
6150
G
T
A
G
C
C
A
T
G
A
G
C
C
A
A
G
A
T
C
A
C
G
C
C
A
T
T
G
C
A
C
T
C
C
A
G
C
C
T
G
G
G
C
A
A
C
A
A
G
A
6200
G
T
G
A
A
A
C
T
C
C
G
T
C
T
C
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
G
A
A
C
T
A
A
T
A
T
T
T
A
A
G
T
C
T
G
G
6250 |
REPEAT
C
A
C
G
G
T
G
G
C
T
C
A
C
A
C
C
T
G
T
G
A
T
C
C
T
A
G
C
A
C
T
T
C
A
G
G
A
G
G
C
T
G
A
G
G
C
A
G
G
T
6300
G
G
A
T
C
A
C
C
T
G
A
G
T
T
C
A
G
G
A
G
T
T
C
A
A
G
A
C
C
A
G
C
C
T
G
G
C
C
A
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6350
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A
6400
T
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6450
G
A
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C
C
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6500
C
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6550
G
G
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G
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A
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6600
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6650
T
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6700
C
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C
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A
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A
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G
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C
C
6750
C
A
G
G
G
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C
C
T
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G
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A
6800
C
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C
T
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A
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A
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A
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C
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6850
C
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C
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A
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C
C
C
6900
C
C
A
T
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A
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C
C
T
C
C
C
G
G
G
C
C
A
T
C
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A
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6950
C
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A
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A
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7000
G
T
C
A
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A
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A
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G
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A
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A
A
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C
C
T
T
G
7050 |
REPEAT
G
A
T
T
A
A
G
A
A
T
G
T
T
A
T
C
A
T
C
G
G
C
C
A
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G
T
G
G
T
G
G
C
T
C
A
T
G
C
C
T
G
T
A
A
T
C
C
7100 |
REPEAT
C
A
G
C
A
T
G
C
A
C
T
T
T
G
G
G
A
G
G
C
T
G
A
G
G
C
G
G
G
T
G
G
A
T
C
A
C
A
A
G
G
T
C
A
A
G
A
G
T
T
7150
T
G
A
G
A
C
C
A
G
C
C
T
G
G
C
C
A
G
C
A
T
G
G
T
G
A
A
A
C
C
C
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T
C
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C
T
A
C
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A
A
A
A
A
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A
C
A
7200
A
A
A
A
A
T
T
G
G
C
A
A
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G
C
A
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A
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T
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T
A
A
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A
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C
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A
C
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A
G
G
7250
A
G
G
C
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G
A
G
G
C
A
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C
A
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A
A
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C
G
C
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A
A
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C
C
A
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G
A
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C
G
G
A
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G
T
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A
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T
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A
7300
G
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A
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A
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A
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A
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C
A
C
T
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C
A
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C
C
A
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A
A
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A
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A
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A
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G
7350
T
C
T
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A
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A
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A
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T
C
A
T
T
T
C
C
A
A
A
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C
C
T
T
A
G
7400 |
REPEAT
T
A
C
C
T
T
G
T
A
C
A
A
G
T
G
C
C
C
A
T
C
A
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A
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A
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A
A
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A
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7450
G
A
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A
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C
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A
A
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A
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A
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C
A
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A
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T
C
T
A
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C
7500
G
G
C
C
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C
A
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A
A
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T
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A
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C
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A
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A
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A
7550
T
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A
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7600
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G
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C
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A
A
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A
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A
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T
7650
G
T
G
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A
A
A
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A
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A
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A
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A
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G
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G
C
G
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C
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C
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C
T
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T
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C
A
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C
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T
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G
7700
G
G
C
G
G
T
T
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A
C
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T
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G
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A
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A
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A
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7750
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7800
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C
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7850
T
G
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C
C
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A
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A
A
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A
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7900
C
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C
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C
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A
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7950
G
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A
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C
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A
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G
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A
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G
C
C
A
8000 |
REPEAT
A
G
A
T
G
G
G
A
A
G
A
A
G
A
T
T
G
T
T
T
C
A
G
G
C
C
A
G
G
A
G
T
T
T
C
A
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A
C
C
A
G
C
T
T
G
G
G
C
A
8050
A
C
A
T
A
G
C
A
A
G
A
C
T
C
C
A
T
C
T
C
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C
A
A
A
A
A
A
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A
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A
A
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A
A
G
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A
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C
C
A
G
G
T
A
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G
8100
G
T
G
G
C
A
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C
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G
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A
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8150
C
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A
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8200
C
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G
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A
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A
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8250
A
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G
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8300
C
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8350
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8400
A
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8450
G
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8500
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8550
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8600
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8650
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8700
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8750
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8800
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8850
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8900
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8950
T
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C
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G
A
G
A
A
A
T
G
A
G
C
A
G
C
C
T
9000
G
C
A
G
T
A
T
G
C
G
C
T
C
A
C
T
C
T
G
C
A
C
C
G
A
G
T
C
A
G
T
T
G
C
T
T
A
C
C
T
A
A
A
A
A
A
C
A
A
A
9050
C
A
T
T
G
A
G
A
T
A
C
T
C
A
A
T
G
A
T
A
T
G
T
G
T
G
A
T
G
T
T
T
A
A
T
A
T
T
T
T
A
A
C
A
G
T
A
A
G
C
9100
A
A
A
C
C
T
T
T
T
A
T
A
G
A
G
A
G
G
G
G
A
A
A
A
G
G
T
T
T
G
C
C
T
T
C
C
C
T
T
T
C
C
T
G
A
C
T
G
T
G
9150
T
C
C
C
G
G
G
A
C
T
A
G
T
G
A
A
G
A
G
A
G
C
C
T
C
T
T
C
A
A
A
G
G
G
A
A
G
T
T
C
T
T
G
A
A
G
C
T
C
T
9200
G
C
T
C
T
T
G
T
C
C
T
C
T
T
G
C
T
G
G
G
C
A
G
A
G
G
C
G
G
C
A
G
C
T
T
T
A
G
G
A
G
T
G
G
C
T
GGAG
9250
TCCTGAGTGT TTAACTTAGA GTAGCTGATG GGGGCTCAGC CGGGGCCGGT
9300
CCTGGGCCTC AGTCATCAGC ACTTCTGGAG ACTCTGCCGC CTCGGCGTCA
9350
AGTGCAGAAG GAACATTAAC TTCTTTCTCT TGTGTACATT TGCTTTTGTA
9400
ACAAAAAACT TGCCAGATTT TGTAATTCTA GGATCTCTTC CTTTAAACTC
9450
CTTTTGCTGA AACAGAACAG ATGCAAGCGT AGTGTTCAGT GAGACTTTAG
9500
GTAAAGCCTC ACACGTATCA GGCAACAAGC TGGGTGCCGT GGGGGCACAG
9550
AGATAAAACC TC
G
G
C
A
G
G
G
C
A
C
A
G
T
G
G
C
T
C
A
C
G
C
C
T
G
T
A
A
T
C
C
C
C
A
C
A
C
T
9600 |
REPEAT
T
T
G
G
G
A
G
G
C
C
G
A
G
G
C
G
G
G
C
G
G
A
T
C
A
C
T
T
G
A
G
G
T
C
A
G
G
A
G
T
T
T
G
A
G
A
C
C
A
G
9650
C
C
T
A
G
C
C
A
A
C
A
T
G
G
C
A
A
A
A
C
T
C
C
G
T
C
T
C
T
A
T
T
A
A
A
A
A
T
A
C
A
A
G
A
A
T
T
A
G
C
9700
C
G
G
G
C
G
T
G
G
T
G
G
C
A
T
G
T
G
C
C
T
G
T
A
G
C
T
A
C
T
T
G
G
G
A
G
G
C
T
G
A
G
A
T
G
G
G
A
G
G
9750
A
T
C
A
C
T
T
G
A
A
C
C
T
G
G
G
A
G
G
T
G
G
A
G
G
T
T
G
T
T
G
T
G
A
G
C
C
G
A
G
A
T
C
G
T
G
C
C
C
A
9800
G
C
C
T
C
G
G
C
G
A
C
A
G
A
G
C
G
A
G
A
C
T
C
T
G
T
C
T
C
A
G
A
A
A
A
A
A
A
G
A
A
A
A
G
A
A
A
A
G
A
9850 |
var(9839):[A:0.23]
A
A
A
G
A
A
A
A
CT TCTATTAAGG TGATGGGGCT TAGGGGTCTT TTTTACCTTT
9900
CAGTTTCTGA TGTTATGTTC TAGGAGTGAT ATGCAAAACT TGTATGAAGT
9950
TGGAAGTTGT TCTGTGTTTT TAGGACCCAC AGGTTGTAG
T
A
G
T
G
T
A
G
T
A
G
10000 |
REPEAT
T
T
A
G
A
A
G
A
C
A
G
A
C
T
T
G
G
A
A
G
T
T
A
A
A
A
C
A
A
G
C
C
A
A
G
G
T
T
C
A
A
G
C
C
C
T
G
A
C
T
10050
T
G
G
C
A
G
C
T
T
C
T
T
G
C
T
G
T
G
T
G
A
T
T
T
T
G
G
G
C
C
A
G
G
C
A
T
T
T
C
C
T
C
C
T
T
G
T
T
T
C
10100
T
T
C
G
T
C
T
G
C
A
A
A
A
G
G
G
T
G
A
T
GTTCC
A
G
G
T
C
A
G
G
A
G
A
T
C
G
A
G
A
C
C
A
T
C
C
T
G
10150 |
var(10104):[A:0.04]
|
REPEAT
G
C
T
A
G
C
A
C
A
G
G
G
A
A
A
C
C
C
T
G
T
G
T
C
T
A
C
T
G
A
A
A
A
A
T
A
C
A
A
A
A
A
A
A
A
T
T
A
G
C
10200
C
G
G
G
C
G
C
T
G
T
G
G
T
G
G
G
T
G
C
C
T
G
T
A
G
T
C
C
C
A
G
C
T
A
C
T
C
G
G
G
A
G
G
C
T
G
A
G
G
C
10250 |
var(10213):[C:0.26]
A
G
G
A
G
A
A
T
G
G
C
G
T
G
A
A
C
C
T
G
G
G
A
G
G
C
G
G
A
G
T
T
T
G
C
A
G
T
G
A
A
C
A
G
A
G
A
T
C
G
10300
C
G
G
C
A
C
T
G
C
A
C
T
C
C
A
A
C
C
T
G
G
G
A
G
A
C
A
G
A
G
T
A
A
G
A
C
T
C
C
G
T
C
T
C
A
A
A
A
A
A
10350
A
A
A
A
A
A
A
A
A
A
A
A
A
G
G
G
T
G
G
T
G
T
T
G
C
C
A
G
A
A
G
C
C
A
G
G
A
G
A
G
G
A
T
G
A
G
G
A
G
G
10400 |
NOT SCANNED
T
T
G
T
A
G
A
A
G
C
A
G
A
G
T
G
C
T
T
A
C
A
A
G
C
A
G
G
A
A
A
G
C
A
G
A
G
T
T
T
C
A
G
C
T
G
G
G
T
A
10450 |
REPEAT
C
A
G
T
G
G
C
T
C
A
C
A
C
C
T
G
T
C
A
T
C
C
C
A
A
C
A
C
T
G
T
G
A
G
A
G
G
C
C
A
A
G
G
T
C
G
G
C
G
G
10500
A
T
C
A
C
T
T
G
A
G
G
T
C
A
G
G
A
G
T
T
T
G
A
G
A
C
C
A
G
C
C
T
G
G
C
C
A
A
A
G
T
G
G
T
G
A
A
A
C
C
10550
C
C
A
T
C
T
C
T
A
C
T
A
A
A
A
A
T
A
C
A
A
A
A
G
T
T
A
G
C
T
G
G
A
T
G
T
G
G
T
G
G
T
G
G
G
T
G
C
T
T
10600
G
T
A
A
T
C
C
C
A
G
C
T
A
T
T
T
G
G
G
A
G
G
C
T
G
A
G
G
T
A
G
G
A
G
A
A
T
C
G
C
T
T
G
A
A
C
C
T
G
G
10650
G
A
G
G
T
G
G
A
G
G
T
T
G
C
A
G
T
G
A
G
C
T
G
A
G
A
T
G
G
C
A
C
C
A
C
G
G
C
A
C
T
C
C
A
G
C
C
T
G
G
10700
G
C
C
A
C
A
A
G
A
G
T
G
A
A
A
C
T
C
T
G
T
C
T
C
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
T
A
G
A
G
C
T
T
A
10750
T
A
T
T
C
T
T
T
T
T
T
T
T
T
T
T
T
T
T
T
T
T
G
A
G
A
C
A
G
G
G
T
C
A
T
C
T
C
G
G
A
G
C
T
G
A
T
G
A
C
10800 |
REPEAT
T
C
T
G
A
G
T
T
A
G
C
A
C
C
A
T
C
T
C
G
G
T
T
C
A
C
T
G
C
A
A
C
C
T
C
C
A
C
C
T
C
C
T
G
G
G
T
T
C
A
10850
A
G
C
A
A
T
C
C
T
C
C
C
A
C
C
T
C
A
G
C
C
T
C
C
C
G
A
G
T
A
G
C
T
G
G
G
A
C
A
G
G
C
A
C
A
C
G
T
C
A
10900
C
C
A
C
A
C
C
T
G
G
C
T
A
A
T
T
T
T
T
G
T
G
T
T
T
T
T
A
G
T
A
G
A
G
A
C
A
G
G
G
T
T
T
T
G
C
C
A
T
G
10950
T
T
G
G
C
T
G
G
G
T
T
G
G
T
C
T
T
A
A
A
C
T
C
C
T
G
A
C
C
T
C
A
G
G
T
G
A
T
C
C
G
C
C
C
A
G
C
T
C
A
11000 |
var(10991):[A:0.12]
G
T
C
T
T
C
C
A
A
A
G
T
G
C
T
G
G
A
A
T
T
G
T
T
C
A
G
G
C
A
T
G
A
G
C
C
A
C
C
G
T
G
C
C
C
G
G
C
C
A
11050
GGTGTTTATT TTCTAAATCC AAAATTTTTT ATCAGATCTG CTCAGTTTTA
11100
AGTAACATCC TCAAAATCTA TTTTGCTCTT CTGTTTTCTA ACTTGGTAAG
11150
AGGTGTTTTA TAATTATTTT CCAAATTACA CTCAA
A
C
A
C
C
T
T
C
C
A
T
C
T
G
T
11200 | Exon 1 |
UTR
C
C
A
A
A
G
G
T
G
C
T
G
G
A
G
A
G
T
C
A
T
G
C
C
T
G
T
G
A
G
C
C
C
T
G
G
G
C
A
C
C
T
C
C
T
G
A
T
G
T
11250
C
C
T
G
C
G
A
G
G
T
C
A
C
G
G
T
G
T
T
C
C
C
A
A
A
C
C
T
C
A
G
G
G
T
T
G
C
C
C
T
G
C
C
C
C
A
C
T
C
C
11300 |
var(11251):[T:0.12]
A
G
A
G
G
C
T
C
T
C
A
G
G
C
C
C
C
A
C
C
C
C
G
G
A
G
C
C
C
T
C
T
G
T
G
C
G
G
A
G
C
C
G
C
C
T
C
C
T
C
11350
C
T
G
G
C
C
A
G
T
T
C
C
C
C
A
G
T
A
G
T
C
C
T
G
A
A
G
G
G
A
G
A
C
C
T
G
C
T
G
T
G
T
G
G
A
G
C
C
T
C
11400
T
T
C
T
G
G
G
A
C
C
C
A
G
GTGAGTT CCCTGGTACT GCCCTGCAGC CTGTGTGGGA
11450
AGGGGGGTGG TCTATCTTTC TGACCTTCTC TCCCAGCCCT GGGACTGGAG
11500
AGGACAAGAT TAAGCATGGG GATCTTTCCT TTCTTGGCCA GACTTCCAGT
11550
AAGGGAGGTT GTCTGTTCCT CTAACCAGAA GACTTCTTTG AACTGTGACG
11600
GTTTTATATT CCTCACTTGG TAGAGGCAGA ACGTTCATCT CAGCCAACCC
11650
CACGCCCATC TGGAGTGTAC TTCCCCGGGA TGATGGCCCC AAATGGAGGC
11700
ACCGGCCTCT TCTTTTTGCC TAAACCACTT CTAGAAAC
C
T TTTATAAACC
11750 |
var(11739):[G:0.01]
ACAGGCCTTA ATGTGTATCT TT
A
A
G
T
C
A
C
T
G
C
T
G
T
T
T
T
A
T
T
C
A
T
C
A
T
C
A
G
11800 |
NOT SCANNED
C
A
A
C
T
G
A
C
T
T
T
G
A
G
A
C
A
G
G
T
C
T
T
C
T
A
C
C
T
T
A
T
T
A
A
T
T
T
T
A
A
A
A
G
A
A
T
T
G
G
11850
G
A
T
A
A
T
T
T
A
T
T
A
A
G
T
T
G
C
C
C
C
T
T
A
A
T
A
G
C
A
C
T
T
C
A
T
A
C
T
A
T
T
T
T
A
G
C
T
T
T
11900
A
A
T
T
T
C
T
T
C
A
C
T
T
T
T
T
A
A
C
A
A
T
A
T
G
A
T
T
C
A
T
T
A
A
A
A
G
T
C
A
T
A
T
T
T
T
A
A
A
T
11950
T
A
A
T
T
T
T
T
A
A
C
T
G
T
T
T
G
C
A
G
T
T
G
T
A
T
T
T
C
A
T
G
T
A
A
A
T
A
T
T
T
A
T
T
G
A
C
T
A
C
12000
C
C
T
T
T
A
A
A
G
C
A
T
A
A
A
T
T
T
T
G
A
A
T
A
T
T
A
T
T
A
G
A
T
A
T
C
A
A
C
A
G
C
C
A
C
A
T
C
T
T
12050
A
A
A
A
A
A
A
A
A
A
A
A
A
A
G
C
A
A
G
A
G
T
T
T
T
A
A
T
T
T
A
A
A
A
A
G
A
G
C
C
T
T
G
A
T
A
T
A
A
A
12100
T
G
A
T
T
T
T
C
A
A
T
G
G
A
C
T
G
A
A
A
C
C
A
A
A
C
C
A
A
A
A
G
T
A
A
A
A
T
G
G
G
T
C
A
T
T
T
A
A
A
12150
A
A
AAAAAAAA AACCCTTCCC
C
GTGCGCTGG AGTCTCCCGG GTCATTGTCG
12200 |
var(12171):[T:0.05]
GGGAGCGCTA GCTCATGGTG ATCTAGGAAT GACTCGCTAA TTGTTTGCCT
12250
TTCTATCCCG TGCATCTTAA CCTGGCTGAT GGATGATGTT GGGTTTGGAT
12300
CAG
C
C
A
T
G
A
G
T
G
T
G
G
A
G
C
T
G
A
G
C
A
A
C
T
G
A
A
C
C
T
G
A
A
A
C
T
C
T
T
C
C
A
C
T
G
T
G
12350 | Exon 2 |
UTR
|
var(12304):[G:0.01]
A
G
T
C
A
A
G
G
A
G
G
C
T
T
T
T
C
C
G
C
A
C
A
T
G
A
A
G
G
A
C
G
C
T
G
A
G
C
G
G
G
A
A
G
G
A
C
T
C
C
12400 |
var(12381):[T:0.01]
|
var(12399):[G:0.11]
T
C
T
C
T
G
C
C
T
G
C
A
G
T
T
G
T
A
G
C
G
A
G
T
G
G
A
C
C
A
G
C
A
C
C
A
G
G
G
G
C
T
C
T
C
T
A
G
A
C
12450
T
G
C
C
C
C
T
C
C
T
C
C
A
T
C
G
C
C
T
T
C
C
C
T
G
C
C
T
C
T
C
C
A
G
G
A
C
A
G
A
G
C
A
G
C
C
A
C
G
T
12500 |
var(12466):[A:0.13]
C
T
G
C
A
C
A
C
C
T
C
G
C
C
C
T
C
T
T
T
A
C
A
C
T
C
A
G
T
T
T
T
C
A
G
A
G
C
A
C
G
T
T
T
C
T
C
C
T
A
12550
T
T
T
C
C
T
G
C
G
G
G
T
T
G
C
A
G
C
G
C
C
T
A
C
T
T
G
A
A
C
T
T
A
C
T
C
A
G
A
C
C
A
C
C
T
A
C
T
T
C
12600
T
C
T
A
G
C
A
G
GT TAGCAGC
T
CA TGAACTCTTG AAGTTCATGA GATGAACTTA
12650 |
var(12606):[G:0.07]
|
var(12618):[A:0.07]
ACTCTGGGTT CAGTGTCTGT GTTCC
T
T
T
T
T
C
T
T
A
C
T
T
T
A
T
T
T
G
T
A
T
A
G
A
G
12700 |
REPEAT
A
T
A
G
G
G
T
C
T
T
G
C
T
A
T
G
T
T
G
C
C
C
A
G
G
C
T
G
G
T
C
T
C
G
A
A
C
T
C
C
T
G
G
G
C
T
T
A
A
G
12750
G
G
A
T
C
C
T
C
C
T
G
C
C
T
C
G
G
C
C
T
C
C
C
A
A
A
G
T
G
C
T
G
G
G
T
T
T
A
C
A
A
G
C
A
T
G
A
G
C
C
12800 |
var(12766):[A:0.06]
A
C
C
A
C
A
C
C
C
A
G
C
C
TCTGTTT CTGATATTTG AAATTTAGTA AGACAGATTT
12850
TAGCTAAATT GAGGGAATAC CTTTACAGAT CTAAGCTCTC ATTTCTGCTA
12900
TCACCTGTAT TTGATCATCT TTTGGCAGA
T
TTTTTTTCCC CATTATATGT
12950 |
var(12930):[:0.91]
GCCAGATTTA AATATCATGT TCCTATATAA TATAGGATAG ATTATTTTTT
13000
GGATGAATTT
T
CGTTGGACA GATGGTAAAG ATGAAAATGG C
A
G
C
T
G
G
G
C
A
13050 |
var(13011):[G:0.03]
|
REPEAT
C
A
G
T
G
G
C
T
C
A
C
G
C
C
T
A
T
A
A
T
C
C
C
A
G
C
A
C
T
T
T
G
G
G
A
G
G
C
T
G
A
G
G
C
G
G
G
C
G
G
13100
A
T
C
A
T
T
T
G
A
G
G
T
C
A
G
G
A
G
T
T
C
A
A
G
A
C
C
A
G
C
C
T
G
G
C
C
A
A
C
A
T
G
G
T
G
A
A
A
C
C
13150
C
C
A
T
C
T
C
T
A
C
T
A
A
A
A
A
T
A
T
A
A
A
A
A
T
G
A
G
T
C
A
G
G
C
G
T
G
G
T
G
G
C
A
G
G
C
G
C
C
T
13200
G
T
A
A
T
C
C
C
A
G
T
T
A
C
T
C
A
G
G
A
G
G
C
T
G
G
G
G
T
A
G
G
G
G
A
A
T
C
G
C
T
T
G
A
A
A
C
C
A
G
13250
G
A
G
G
C
G
G
A
G
G
T
T
C
C
A
T
T
G
A
G
C
C
A
A
G
A
T
C
A
C
G
C
C
A
C
T
G
T
A
C
T
C
C
A
G
C
C
T
G
G
13300
G
T
G
A
C
A
G
A
G
C
A
A
G
A
C
T
C
T
G
T
T
T
C
C
A
A
A
A
A
A
A
A
C
A
G
A
A
A
A
A
A
G
A
A
A
A
A
G
A
A
13350
A
A
TGGCTAGT CTTTTTGCTG CGAGGCTCTG ATGCCAGTAC CTGTAATAAC
13400
AACAGGAAAA GCCGGTCTTT AGGGCCAAGG AGAGGGTGTG ACTGATGGCC
13450
CCACCAGCAT GTCTGCCTAC CCGGGCCTGC TCCGGGGCAG CAAGGCCAAT
13500
GGGGGCCAGA ATTCCAAG
T
C CCTCCTTTCC CCTTCCCTGC ACAGCTCTCT
13550 |
var(13519):[C:0.11]
CCAA
G
CCTTA GAAATCACCC AGGACACTAT GTTCAGTTTT CTTTTATGGG
13600 |
var(13555):[A:0.11]
TTCAGTGTTG GTTAAGAATA AAGCTGGTCA GTCAGTAAGT GGAATTCCAT
13650
AAGCCTGAAT ATTTTGGTAA TAAATAGCAA ATCCATATTA ACCACCAAGA
13700
ACATCCTAAT AGC
G
TTTATC AAATGGTAAA TAGCACTACA
A
G
G
A
T
G
A
A
G
C
13750 |
var(13714):[A:0.11]
|
REPEAT
T
G
G
A
G
G
A
T
T
G
C
T
T
G
A
G
G
C
C
A
G
G
A
G
T
T
C
G
A
G
A
C
C
A
G
C
C
G
G
G
T
G
T
T
G
G
T
G
G
C
13800 |
REPEAT
A
T
G
C
A
C
C
T
G
T
A
G
T
T
C
C
A
C
C
T
A
C
T
C
G
G
G
A
G
G
C
T
G
A
G
G
T
G
G
G
A
G
G
A
T
C
A
C
G
A
13850 |
var(13849):[A:0.10]
G
C
C
C
A
G
G
A
G
G
T
T
G
A
G
G
C
T
G
C
A
G
T
G
A
G
C
T
G
T
G
A
T
C
G
C
A
C
C
A
T
G
G
C
A
C
T
C
C
A
13900
G
C
C
T
G
G
G
C
A
A
C
A
G
A
G
C
A
G
G
A
C
C
C
T
G
T
C
T
C
A
A
A
A
G
A
A
A
C
A
A
A
A
A
A
A
A
TTTT
13950
AAAAACTACT GCAGAAGTCA CAGTGCACAT AAAAAGCATG TCATTGATCT
14000
TACATTCACC AAGGAACAAG TTGGGCTCCA AAAAGACTAT GCTCTTTGGG
14050
T
T
T
T
T
T
T
G
G
T
G
T
T
T
G
T
T
T
G
T
T
T
G
T
G
A
C
A
G
A
G
C
C
T
T
A
C
T
C
T
G
T
T
G
C
C
C
C
C
A
14100 |
REPEAT
|
var(14076):[G:0.13]
|
var(14082):[T:0.28]
G
G
C
T
G
G
A
G
G
G
C
A
G
T
G
G
C
A
C
G
A
T
C
T
T
G
G
C
T
C
A
C
T
G
C
A
A
C
C
C
C
C
G
C
C
T
C
C
C
G
14150 |
var(14138):[T:0.04]
G
G
T
T
C
A
A
G
C
G
A
T
T
C
T
C
C
T
G
C
C
T
C
A
G
C
C
T
C
T
C
G
A
G
T
A
G
C
T
G
G
G
A
T
T
A
C
A
G
G
14200
C
G
C
C
T
G
C
C
A
C
C
A
C
G
C
C
T
G
G
C
T
A
A
T
T
T
T
T
G
T
A
T
T
T
T
C
A
G
T
A
G
A
G
A
C
G
G
G
G
T
14250
T
T
C
A
C
C
A
T
G
T
T
G
G
C
C
A
G
G
C
T
T
G
T
C
T
C
G
A
A
C
T
C
C
T
G
A
T
T
T
C
A
A
G
T
G
A
T
C
C
A
14300
C
C
T
G
C
C
T
C
G
G
C
C
T
C
C
C
A
A
A
G
T
G
T
T
G
A
G
A
T
T
A
C
A
G
G
C
A
T
G
A
G
C
C
A
C
T
G
C
A
C
14350 |
var(14319):[G:0.01]
C
T
G
G
C
C
G
AAA AGACTATGCT CTTTGGATGT GCAGGGTAGA GGATTGAGGG
14400 |
var(14357):[A:0.14]
TGGGCATGGC ACAGGCCTTG TACCCTTCCC TCCAGGGGTG TTTGGAGTTA
14450
AAGTGGCACA AAAGAAGGTG AGAGACATGG AGGAAAAAGG GTCCATGGCT
14500
TTTCCCCAAA TCCCCACTCT GCGTGTTTCT ATTGCGCACC CACACTCTCT
14550
GTCTTTGGTC TGTAACTAG
C
A
C
T
G
G
G
C
G
T
C
C
C
T
T
T
C
A
G
C
A
A
G
A
C
G
A
T
G
G
C
14600 | Exon 3 |
UTR
M A 2
T
G
T
G
C
T
C
A
G
G
C
A
G
C
T
G
G
C
G
C
T
C
C
T
C
C
T
C
T
G
G
A
A
G
A
A
C
T
A
C
A
C
C
C
T
G
C
A
G
G
14650
V L R Q L A L L L W K N Y T L Q 18
TGCGTCCAGA CTCTGGAGGG AGGTCAGCTG CGTGCCTAGC CCAGAGGCT
C
14700 |
var(14700):[T:0.01]
CTGGGGATGC CCTTGAGGGA AGGGCTGTCT GCATGCCCCT GCTTCTGCCT
14750
TGCAGCCCAT CACCGTGCCC TATTGTATCT CTTCCAG
A
A
G
C
G
G
A
A
G
G
T
C
C
14800 | Exon 4
K R K V 22
T
G
G
T
G
A
C
G
G
T
C
C
T
G
G
A
A
C
T
C
T
T
C
C
T
G
C
C
A
T
T
G
C
T
G
T
T
T
T
C
T
G
G
G
A
T
C
C
T
C
14850
L V T V L E L F L P L L F S G I L 39
A
T
C
T
G
G
C
T
C
C
G
C
T
T
G
A
A
G
A
T
T
C
A
G
T
C
G
G
A
A
A
A
T
G
T
G
C
C
C
A
A
C
G
C
C
A
C
C
A
T
14900
I W L R L K I Q S E N V P N A T I 56
C
T
A
C
C
C
G
G
G
C
C
A
G
T
C
C
A
T
C
C
A
G
G
A
G
C
T
G
C
C
T
C
T
G
T
T
C
T
T
C
A
C
C
T
T
C
C
C
T
C
14950
Y P G Q S I Q E L P L F F T F P 72
C
G
C
C
A
G
G
A
G
A
C
A
C
C
T
G
G
G
A
G
C
T
T
G
C
C
T
A
C
A
T
C
C
C
T
T
C
T
C
A
C
A
G
T
G
A
C
G
C
T
15000
P P G D T W E L A Y I P S H S D A 89
G
C
C
A
A
G
A
C
C
G
T
C
A
C
T
G
A
G
A
C
A
G
T
G
C
G
C
A
G
G
G
C
A
C
T
T
G
T
G
A
T
C
A
A
C
A
T
G
C
G
15050
A K T V T E T V R R A L V I N M R 106
A
G
GTGAGACA TGCCGGGGCT CTCGGTGCCA GGCCTAGTGG TGCCTCCACG
15100
106
C
A
GCTGGGCA GGCAGGGGTC GAGCCCAGGA TGTGCGAAGC AGCTGGGTGA
15150 |
var(15102):[G:0.28]
GGAGTTCACC CTGTGCAGAC TTGGCCTCTG CTTCTTCCCG CATCACTACT
15200
TCAACCTGTA AAAGGCACTG CTGTTCCTTA AACCTCTGCC TGCCTGCGAG
15250
TAAATAGCAG TCTCTCCTTT GGGTCCGATA GCACCATCAC AGTCCCCACC
15300
AAAGGGACCC TGGTGACATT TTAACCCATG GGGCAGAACA GGTTAGAAAA
15350
TGCACCTGCC TGCAGTTGCC CCAGGCTCCT TTCTGTTCCC TCATTTTATG
15400
AAAGACATTA CTGGTCTCCA GGCCTCTGTG AACAGAGTCC AATAAGATAC
15450
ATAAGGAAAG TAGCAGATAT TTGGGACTTA AATACGACCT GGCAGAAAAA
15500
GGGAAAAAAG AAAGTGAGGT TTTTGCTTGC CTGATGGC
A
C TAAGACTAGG
15550 |
var(15539):[C:0.17]
AAGCCATCAA GCCCATCTAG CATCAAATCT CTTCTCGGCG GCTGAGCCAC
15600
CCAAGGAATC CCCCAGCTTC TCTGTGGCCA TGCCTGATTG TACAATGGGA
15650
CCAGGGCTGG CCGCCCACCT GTGCAGAGCT GTGAGGACCC CGGGGAGCAG
15700
CAGGTGCAGC AGCCTTAGCA GTACCAGGCC CTGGAACTGC ATCTGATGGT
15750
CAGTAGGGTG GACAGGACTT TACAGGGATG CCTGGGTGGA CTTGAGCCAG
15800
GGAAAGCCCT TCTGTGACAA GGGCAGGGCA CAGTTTGACC GTGTGGTGCC
15850
AAGAACCTTT TCTGGGACGT GGTTTTGGGT GGGCAGCTCT GAAAACAGTG
15900
ATGAGAAAGC CTGAGAAGGG AACTCCCACT GTGAGTGCTG CTCACCGTTC
15950
CTAAAC
C
C
T
T
G
C
T
GTCGGGA TGAAAGCTGT CCTCCATTTT CCCCTCCTCA
16000 |
var(15957):[:0.02]
TTTGGGCATT TACCTCCCGG GCTTTAATTC C
T
TGTAGCAA ATACTCAGAG
16050 |
var(16032):[C:0.02]
GAAGTGCCTT GGTCCCTCAC AAAATGACGA CAGTAAAACC CTTTCTGAAT
16100
TGTTAAGGAG TGTCCAGATG ATAGAAAAAG CCTTTGAGAC ACTCTGAGTT
16150
AGCATCCACT CCATT
T
C
TAA AAACACACCA TTCTGGTTTT GAGAAAGAGA
16200 |
var(16166):[C:0.01]
|
var(16167):[G:0.12]
AGCCACCC
C
G GGCTGCAGAG CCCACTGCAG GGTGGGTGGT GGGTTTGCTC
16250 |
var(16209):[T:0.02]
CCCTGGGCCT TGCTGCAGGC GCTACCCGGA GCCTCCAGCT CTGCTCCAAA
16300
A
AACCCGCAC CAGGAGAACT CACTGCCTGG GGCTCTGACC CTGCCATTCT
16350 |
var(16301):[G:0.02]
GCCCTCCTTG ATGGCAGCTT GTCTCTCTGC CAAAGATGAA AGCTGCCTTG
16400
AGTCTCAGGA AGGGTTTACA AAGCCCTAGA GGATTTGCCG TCTTTCATCT
16450
G
CCAGTGACC TGAACCACGC AGATTTTTCA AGCAGGAGGG CCGATTGGGC
16500 |
var(16451):[T:0.01]
AACCACAGCT CCC
G
TGCTCT CTCTTTGCAG
T
G
C
G
C
G
G
C
T
T
T
C
C
C
T
C
C
G
A
G
16550 |
var(16514):[A:0.01]
| Exon 5
V R G F P S E 113
A
A
G
G
A
C
T
T
T
G
A
G
G
A
C
T
A
C
A
T
T
A
G
G
T
A
C
G
A
C
A
A
C
T
G
C
T
C
G
T
C
C
A
G
C
G
T
G
C
T
16600
K D F E D Y I R Y D N C S S S V L 130
G
G
C
C
G
C
C
G
T
G
G
T
C
T
T
C
G
A
G
C
A
C
C
C
C
T
T
C
A
A
C
C
A
C
A
G
C
A
A
G
G
A
G
C
C
C
C
T
G
C
16650 |
var(16629):[C:0.01]
A A V V F E H P F N H S K E P L 146
C
G
C
T
G
G
C
G
GT GAGACGTGCG GCCGGGCCGA GCAGTCACAG CCCATCAGC
A
16700 |
var(16700):[G:0.01]
P L A 149
AGGCCTCCGC TTCCTCCCGC GTCACTAGTT CAACCTGTAA AAGGCACTGC
16750
TTTCCCTTAA ACCTCTGCCT GCCTGC
G
AGT CAATAGCAGT CACTCCTTTG
16800 |
var(16777):[A:0.12]
GGTCTGATAA TATCATCACA GTCCCCGCCA AGGGGATCTT GGTGACATTT
16850
AAACCCA
C
GG GTCAGAACAG GTTAGAAAAT GCACCTGCCT GTGGCCGCCC
16900 |
var(16858):[T:0.01]
CAAGCTCCTT TCTGTTCCCT CATTTTATGA AAGATATTAC TGGTCTCCAG
16950
AACAGAGTCT AATAAGATAG TTAAGGAAAG TAGTAGGTAT TTAGGACTTA
17000
AATATGATCT GGCGGAAAGA AAGAAAGTGA GGTTTTTGCT TGCCTGATGG
17050
CATTAAAATT AGGAAGCCAT CAAGTCCATC TAGCATTGTG GTTGGCGGCC
17100
CTCCAGGGAT CCTGAACACT CGGTGGCACT TCACA
A
TGGA ATTAGGAATG
17150 |
var(17136):[T:0.08]
GCCAAGAACC ACCCCCCAAA AGGGGCCCCT GTGTGGCTCC CTGCTCCTGC
17200
TAGGACAGGG ACCACTCAGT GTGACATTCC GGGGCCTGTT GGAGATACTC
17250
AGAGGCGGGG GAGTGGTGAG TTCTCG
T
CTG TGACAGCCCC CCAAGCGCTC
17300 |
var(17277):[G:0.28]
TCCCACTCCA CCCTGTTGTT TGCCCCTCTG TCTGGATCTC TCGGAACAGC
17350
TGGTTTTCTC TTTGTTTCCA CAG
G
T
G
A
A
A
T
A
T
C
A
C
C
T
A
C
G
G
T
T
C
A
G
T
T
A
C
17400 | Exon 6
V K Y H L R F S Y 158
A
C
A
C
G
G
A
G
A
A
A
T
T
A
C
A
T
G
T
G
G
A
C
C
C
A
A
A
C
A
G
G
C
T
C
C
T
T
T
T
T
C
C
T
G
A
A
A
G
A
17450
T R R N Y M W T Q T G S F F L K E 175
G
A
C
A
G
A
A
G
G
C
T
G
G
C
A
C
A
C
T
A
C
T
T
C
C
C
T
T
T
T
C
C
C
G
C
T
T
T
T
C
C
C
A
A
A
C
C
C
A
G
17500
T E G W H T T S L F P L F P N P 191
G
A
C
C
A
A
G
G
G
A
A
C
C
T
A
C
A
T
C
C
C
C
T
G
A
T
G
G
C
G
G
A
G
A
A
C
C
T
G
G TGAGAAGCTC
17550
G P R E P T S P D G G E P 204
GGTTAGGGTT CGTGTTACCA GCCCGGGC
T
G TTGACTAGTG ACAGTCATAT
17600 |
var(17579):[G:0.01]
GGGGGCAGCC CCACTTTGCA AAAGTATTTC TTGAAGAAAT ACTTTTCA
G
G
17650 |
REPEAT
A
C
A
T
T
T
G
G
C
T
T
G
G
T
T
C
C
A
A
G
T
C
T
T
T
G
C
T
G
T
T
G
T
G
A
A
T
A
G
T
G
C
C
G
C
A
A
T
A
A
17700
A
C
A
T
A
C
G
T
G
T
G
C
A
T
G
T
G
T
C
C
T
T
A
T
A
G
C
A
G
C
A
T
G
A
T
T
T
A
T
A
A
T
C
C
T
T
T
G
G
G
17750
T
A
T
A
T
A
C
C
C
A
G
T
A
A
T
G
G
G
A
T
G
G
C
T
G
G
G
T
C
A
A
A
T
G
G
T
A
T
T
T
C
T
A
G
T
T
C
T
A
G
17800
A
T
C
C
C
T
G
A
G
G
A
A
T
C
G
C
C
A
C
A
C
T
G
A
C
T
T
C
C
A
C
A
A
T
G
G
T
T
G
A
A
C
T
A
G
T
T
T
A
C
17850
A
G
T
C
C
C
A
C
C
A
A
C
A
G
T
G
T
A
A
A
A
G
T
G
T
T
C
C
T
A
T
T
T
C
T
C
C
T
C
A
T
C
C
T
C
T
C
C
A
G
17900
C
A
C
C
T
G
T
T
G
T
T
T
C
C
T
G
A
C
T
T
T
T
G
A
A
T
G
A
T
T
G
C
C
A
T
T
C
T
A
A
C
T
G
G
T
A
T
G
A
G
17950 |
NOT SCANNED
A
T
G
G
T
A
T
C
T
C
A
C
T
G
T
G
G
T
T
T
T
G
A
T
T
T
G
C
A
T
T
T
C
T
C
T
G
A
T
G
G
C
C
A
G
T
G
A
T
G
18000
A
T
G
A
G
C
A
T
T
T
T
T
T
C
A
T
G
T
G
T
C
T
T
T
T
G
G
C
T
G
C
A
T
A
A
A
T
G
T
C
T
T
C
T
T
T
T
G
A
G
18050
A
A
G
T
G
T
T
T
G
T
T
C
A
T
A
T
C
C
T
T
T
G
C
C
C
A
C
T
T
T
T
T
G
A
T
G
G
G
G
T
T
G
T
T
T
G
G
T
T
T
18100
T
T
T
C
T
T
G
T
A
A
A
T
T
T
A
T
T
T
G
A
G
T
T
C
A
T
T
G
T
A
G
A
T
T
C
T
G
G
A
T
A
T
T
A
G
C
C
C
T
T
18150
T
G
T
C
A
G
A
T
G
A
G
T
A
G
A
T
T
G
C
A
A
A
A
A
T
T
T
T
C
T
C
C
C
A
T
T
C
T
G
T
A
G
G
T
T
C
C
C
T
G
18200
T
T
C
A
C
T
C
T
G
A
T
G
G
T
A
G
T
T
T
C
C
T
T
T
G
T
T
G
T
G
C
A
G
A
A
G
C
T
C
T
T
G
A
G
T
T
T
A
A
T
18250
T
A
G
A
T
C
C
C
A
T
T
T
G
T
C
A
A
T
T
T
T
G
G
C
T
T
T
T
G
T
T
G
C
C
A
T
T
G
C
T
T
T
T
C
G
T
G
T
T
T
18300
T
A
G
T
C
A
T
G
A
A
G
T
C
C
T
T
G
C
C
C
A
T
G
C
C
T
A
T
G
T
C
C
T
G
A
A
T
G
G
T
A
A
T
G
C
C
T
A
G
G
18350
T
T
T
T
C
T
T
C
T
A
G
G
G
T
T
T
T
T
A
T
G
G
T
T
T
C
A
G
G
C
C
T
A
A
C
A
T
T
G
A
A
G
T
C
T
T
T
A
A
T
18400
C
C
A
T
C
T
C
G
A
A
T
T
A
A
T
T
T
T
T
G
T
A
T
A
A
G
G
T
G
T
A
T
G
G
A
A
G
G
G
A
T
C
T
G
G
T
T
T
C
A
18450
G
C
T
T
T
C
T
A
C
A
T
A
T
G
G
C
T
A
G
C
C
A
G
T
T
T
T
C
C
C
A
G
C
A
C
A
G
G
A
A
G
G
G
G
A
A
C
A
T
C
18500 |
REPEAT
A
C
A
C
A
C
T
G
G
G
G
C
C
T
G
T
T
G
T
G
G
G
G
T
G
G
G
G
G
G
G
C
G
G
G
G
G
G
A
G
G
G
A
T
A
G
C
A
T
T
18550
A
G
G
A
G
A
T
A
T
A
C
C
T
A
A
T
G
T
T
A
A
A
T
G
A
C
G
A
G
T
A
A
A
T
G
G
G
T
G
C
A
G
C
A
C
A
C
C
A
G
18600
C
A
T
G
G
C
A
C
A
T
G
T
A
T
A
C
C
T
A
T
G
T
A
A
C
T
A
A
C
C
T
G
C
A
C
A
T
T
G
T
G
C
A
C
A
C
G
T
A
C
18650
C
C
T
A
A
A
A
C
T
T
A
A
A
G
T
A
T
A
A
T
T
A
A
A
A
A
A
A
A
A
A
AGAAAGAAA TACTTTTCAG
18700
GAACATTTAC TCTTGTTTAT AGGAAAAGTA AAACAT
C
CAG TATAACTGGT
18750 |
var(18737):[T:0.01]
TTCTGAAAGA CTAAAATAAT CCTTGAAGAT AGCAAAGGCC CTTTCTCTAT
18800
ATCCTGGAAG ACGTGCTCTT GAATGAAACA TTTGTATTTC AGC
T
T
T
T
T
T
T
18850 |
REPEAT
C
T
T
T
T
T
T
T
T
T
T
T
T
T
T
C
A
G
A
C
A
G
A
A
T
C
T
T
G
C
T
C
T
G
T
C
G
C
C
A
A
G
C
T
G
G
A
G
T
G
18900 |
var(18880):[G:0.03]
C
A
G
T
G
G
C
G
C
G
A
C
C
T
C
G
G
C
T
C
A
C
T
G
C
A
A
C
C
G
C
T
G
T
G
T
C
C
C
A
G
G
T
T
C
A
A
G
C
G
18950 |
var(18909):[T:0.02]
A
T
T
C
T
C
C
T
G
C
C
T
C
A
A
C
C
T
C
C
C
A
A
G
T
A
G
C
T
G
G
G
A
T
T
A
C
A
G
G
C
G
C
A
C
A
C
C
A
C
19000
C
A
C
G
C
C
C
A
G
C
T
A
A
T
T
T
T
T
G
T
A
T
T
T
T
T
A
G
T
A
G
A
G
A
C
G
G
G
G
T
T
T
C
A
C
C
A
C
G
T
19050 |
var(19035):[T:0.02]
T
G
G
C
C
A
G
G
A
T
G
G
T
C
T
C
G
A
T
C
T
C
T
T
G
A
C
C
T
C
A
T
G
A
T
T
C
A
C
C
C
A
C
C
T
C
G
G
C
T
19100
T
C
C
C
A
A
A
G
T
T
C
T
G
G
G
A
T
T
A
C
A
G
G
C
A
T
G
A
G
C
C
A
C
C
A
C
A
C
C
C
G
G
C
T
GTACGT
19150 |
var(19108):[C:0.01]
CAGCTTTTAA AAGCTCCCGT TTGAGTTCAT GGGGCTTGGT TTACATTTTC
19200
TTTTTCTGCC GGGCCTTCTC TGTGTACAGA CTTACTGGCA TTTTTAGCTC
19250
CGTGGTCCTT GTGCACCTGA TCCATGGTTT GACGGAATCA GTGTGGTGTT
19300
CATGGAAGCC AGATCTTGGT TACTCTGATG CCCCATCAGT GTGTGTCTTC
19350
GTGTGGACCT GGGCAGGTGG TTGGTACGTG TGCCTCCTCT GAAGCATGGT
19400
CTTGTCTTGG AACTGAGCTA GGGACAGCCA AGAAGTGACT CGGACCCAGG
19450
ACTAGGCTTA GCTGTCAGGC CAAGAAAGAC CCCACTGCAG GTTCTGGGTG
19500
GAAGTCCAGG GTGTTCTGGA GAACGTCGTA TTTCACGGGT CTGGCAGGAG
19550
ACAGAACT
C
A TGGAAGTTTG CCATGGAAGT CACAGCAACG TCCCATCCCT
19600 |
var(19559):[A:0.01]
CCATGAGGCA TGATTCTGAG ACACAAGTGC CAGGCAGGCA GGAGACAGCA
19650
TGCATGCAGC CAGCGCTTAG CGATGTCCCT TACTGGTGCC AGGGCTGTCA
19700
CCAGGCTAAT GCTCTAGGGC AAGATTTTAC ATCTAGAACT AAGATGAACA
19750
AGACCTG
G
T
G
T
G
G
G
G
T
G
T
G
T
G
A
G
G
C
C
C
C
A
G
A
G
C
G
A
T
G
C
C
C
T
T
G
A
C
A
G
G
T
C
19800 |
NOT SCANNED
A
C
C
C
A
G
C
C
T
G
G
A
G
C
T
C
A
G
G
A
G
A
A
G
C
T
A
T
G
T
C
C
A
G
C
T
G
T
C
A
C
A
C
A
T
G
A
T
G
C
19850
T
T
G
C
T
G
C
C
T
G
C
A
G
C
A
G
G
G
G
A
C
T
G
C
A
G
G
A
G
G
G
G
A
C
A
C
T
G
G
C
T
G
C
T
G
A
G
A
C
T
19900
G
G
G
G
C
C
C
A
G
G
C
A
G
G
A
G
C
T
G
C
T
C
A
G
C
T
C
C
C
T
C
C
T
G
T
T
T
T
T
G
G
G
G
A
A
C
A
A
T
T
19950
C
C
C
T
A
A
G
C
T
T
G
G
A
A
G
C
A
A
G
A
G
A
A
A
A
C
C
A
A
T
C
T
C
A
A
A
G
G
A
A
A
A
G
A
C
T
G
A
C
A
20000
G
A
T
T
T
C
A
G
C
A
T
G
T
A
C
A
A
A
C
T
G
G
A
A
A
T
T
T
G
C
C
A
G
A
C
A
C
G
A
A
A
A
G
A
C
C
T
A
A
T
20050
G
G
T
G
G
T
T
T
A
A
A
A
A
AAAAAAA AAAAAAGCAC ATAGCAGACT GGGGAAAACC
20100
TTTGTGGCAA ATGACACAGA GTAAATATCT TTTGTTAGAG AAAAAAAGTT
20150
TTGTTATTAA GAATAGTCGG TTAGTCCTCA GCAAGACAGA GAACCTGAGG
20200
GGGAAGAAAA GTTGGCTGGA AAAACAAGCT CCTAGTAAAG CCCCAGGAGA
20250
TATAACGTGT GTGAGACTGG CATGGCACAG G
G
A
C
T
G
G
T
C
A
A
T
T
C
T
A
G
C
C
T
20300 |
NOT SCANNED
C
A
G
T
T
T
T
G
C
C
T
C
C
A
G
A
T
G
T
C
C
A
T
G
C
C
T
T
A
G
A
C
C
C
A
C
T
A
A
T
A
T
G
C
C
T
G
A
T
G
20350
A
G
A
A
T
T
C
A
G
C
C
C
T
C
A
G
G
C
T
G
G
G
C
G
C
A
G
T
G
G
C
T
C
A
C
A
C
C
T
G
T
C
A
T
C
C
C
A
G
C
20400 |
REPEAT
A
T
T
G
G
G
A
G
G
C
T
G
A
G
G
C
A
G
G
C
A
G
A
T
C
A
C
C
T
G
A
G
G
T
C
A
G
G
A
G
T
T
C
G
G
G
A
C
C
A
20450
G
C
C
T
G
G
C
C
A
A
C
A
T
A
G
T
G
A
A
A
C
C
C
C
G
T
C
T
C
T
A
C
T
A
A
A
A
A
T
A
C
A
A
A
A
A
A
A
A
A
20500
A
A
A
A
A
T
T
A
G
C
T
G
G
G
C
G
T
G
G
T
G
G
T
G
T
G
C
A
C
C
T
G
T
A
A
T
C
C
C
A
G
C
T
A
T
T
C
G
G
G
20550
A
G
G
C
T
G
A
G
G
C
A
G
G
A
G
A
A
T
T
G
C
T
T
G
A
A
C
C
C
A
G
G
A
G
G
C
A
G
A
C
G
T
T
G
C
A
G
T
G
A
20600
G
C
C
G
A
G
A
T
C
G
C
G
C
C
A
C
T
G
C
A
C
T
C
C
A
G
C
C
T
G
A
G
T
G
A
G
A
G
A
G
C
A
A
G
A
C
T
G
T
C
20650
T
C
A
A
A
A
A
A
A
A
A
A
A
A
G
G
C
C
G
G
G
T
G
C
A
G
T
G
G
C
T
C
A
C
G
C
C
T
G
T
A
A
T
C
C
C
A
G
C
A
20700 |
REPEAT
C
T
T
T
G
G
G
A
G
G
C
C
A
A
G
G
T
G
G
G
T
G
G
A
T
C
A
T
G
A
G
G
T
C
A
G
G
A
G
A
T
C
C
A
G
A
C
C
A
T
20750
C
C
T
G
G
C
T
A
A
C
A
C
G
G
T
G
A
A
A
C
C
C
C
G
T
C
T
C
T
A
C
T
A
A
A
A
A
T
A
C
A
A
A
A
A
A
T
T
A
G
20800
C
T
G
G
G
C
A
T
G
G
T
G
G
T
G
T
G
C
A
C
C
T
G
T
A
G
T
C
C
C
A
G
C
T
A
C
T
C
G
G
G
A
G
G
C
T
G
A
G
G
20850
C
A
G
G
A
G
A
A
T
C
G
C
T
T
G
A
A
C
C
T
G
G
G
A
G
G
T
G
G
A
G
G
T
T
G
C
A
G
T
G
A
G
C
C
A
A
G
A
T
C
20900
G
C
G
C
C
A
C
T
G
C
A
C
T
C
C
A
G
C
C
T
G
G
G
C
G
A
C
A
G
A
G
T
G
A
G
A
T
T
C
C
G
T
C
T
C
A
A
A
A
A
20950
A
A
A
A
A
A
A
A
G
T
G
A
T
C
A
T
G
T
G
T
G
T
G
A
T
T
T
T
T
T
T
T
G
T
G
T
G
T
T
G
T
G
T
T
A
G
T
T
A
C
21000
A
A
A
G
T
G
G
A
A
G
T
G
A
C
A
A
T
C
A
C
A
T
C
T
C
T
C
T
T
C
T
C
A
T
T
T
G
C
T
G
T
C
A
G
T
G
T
G
T
G
21050
G
T
G
C
G
T
T
T
C
C
T
T
C
C
T
T
C
TCC CGTGGGACCA CTGAGCGGCC ACGGGGGTCC
21100
TGAGCTGAAG T
C
ACTCTGTT GCCCCAAGCA TCTCTTCCCC CATGGACCCC
21150 |
var(21112):[T:0.01]
ATGCACGTGG CCCTCTGCCC TCGAGAGCAG CTCCTCGAGG TGGCTGGGCC
21200
ATCCTCTGCT CC
C
GCACCCA G
G
G
T
A
C
A
T
C
C
G
G
G
A
A
G
G
C
T
T
C
C
T
G
G
C
C
G
T
G
21250 |
var(21213):[T:0.01]
| Exon 7
G Y I R E G F L A V 214
C
A
G
C
A
T
G
C
T
G
T
G
G
A
C
C
G
G
G
C
C
A
T
C
A
T
G
G
A
G
T
A
C
C
A
T
G
C
C
G
A
T
G
C
C
G
C
C
A
C
21300 |
var(21289):[T:0.02]
Q H A V D R A I M E Y H A D A A T 231
A
C
G
C
C
A
G
C
T
G
T
T
C
C
A
G
A
G
A
C
T
G
A
C
G
G
T
G
A
C
C
A
T
C
A
A
G
A
G
G
T
T
C
C
C
G
T
A
C
C
21350
R Q L F Q R L T V T I K R F P Y 247
C
G
C
C
G
T
T
C
A
T
C
G
C
A
G
A
C
C
C
C
T
T
C
C
T
C
G
T
G
G
C
C
A
T
C
C
A
G
T
A
C
C
A
G
C
T
G
C
C
C
21400
P P F I A D P F L V A I Q Y Q L P 264
C
T
G
C
T
G
C
T
G
C
T
G
C
T
C
A
G
C
T
T
C
A
C
C
T
A
C
A
C
C
G
C
G
C
T
C
A
C
C
A
T
T
G
C
C
C
G
T
G
C
21450 |
var(21445):[T:0.01]
L L L L L S F T Y T A L T I A R A 281
T
G
T
C
G
T
G
C
A
G
G
A
G
A
A
G
G
A
A
A
G
G
A
G
G
C
T
G
A
A
G
GTGACTGCC CGCTTTGGCT
21500
V V Q E K E R R L K 291
CCCCAACACT CTAGAAACCG CGCTGTCCTG GGGAGGCCAT GTCCAAAGGC
21550
TTGGTGTTTT AGTA
T
T
T
T
T
T
T
T
T
T
T
T
T
G
A
G
T
T
G
G
A
G
T
C
T
C
G
C
T
C
T
G
T
C
G
C
21600 |
REPEAT
|
NOT SCANNED
C
C
A
G
G
C
T
G
G
A
G
T
G
C
A
G
T
G
G
T
G
C
G
A
T
C
T
C
G
G
C
T
C
A
C
T
G
C
A
A
G
C
T
C
T
G
C
C
T
C
21650
C
C
G
G
G
T
T
C
A
C
G
C
C
A
T
T
C
T
C
C
T
G
C
C
T
C
A
G
C
C
T
C
C
C
G
A
G
T
A
G
T
T
G
G
G
A
C
T
A
T
21700
A
G
G
T
G
C
C
T
G
C
C
A
C
C
A
C
A
C
C
C
A
G
C
T
A
A
T
T
T
T
T
T
G
T
A
T
T
T
T
T
A
G
T
A
G
A
G
A
C
G
21750
T
G
G
T
T
T
C
A
C
C
G
T
G
T
T
A
G
C
C
A
G
G
A
T
G
G
T
C
T
C
A
A
T
C
T
C
C
T
G
A
C
C
T
T
G
T
G
A
T
C
21800
C
G
C
C
C
G
C
C
T
C
G
G
C
C
T
C
C
A
G
A
A
G
T
G
C
T
G
G
G
A
T
T
A
C
A
G
G
C
G
T
G
A
G
C
C
A
C
C
G
T
21850
G
C
C
C
G
G
C
C
G
G
A
G
G
T
C
T
T
T
C
T
A
T
A
T
T
G
C
C
A
A
G
G
C
T
G
G
T
C
T
C
A
A
A
C
T
C
T
T
G
G
21900 |
REPEAT
C
C
T
C
A
A
G
A
A
A
T
T
C
T
C
C
C
A
T
C
T
C
A
G
C
C
T
C
C
C
A
T
C
T
C
A
T
T
C
T
C
C
C
A
C
A
G
T
G
C
21950
T
G
G
G
A
T
T
A
C
A
G
G
C
A
T
G
A
G
C
T
G
T
A
A
C
A
C
C
T
G
G
C
T
A
G
G
G
G
C
T
C
A
T
T
T
T
G
A
G
G
22000
C
T
G
C
C
C
A
G
T
T
G
T
T
C
A
T
C
T
G
C
T
T
G
G
T
G
C
C
A
T
A
A
A
T
A
A
C
T
T
T
C
A
T
A
A
A
A
C
T
A
22050
T
G
C
A
G
C
A
T
T
G
A
G
G
G
A
G
T
C
A
G
C
A
G
T
G
G
G
C
T
A
T
A
A
A
A
T
G
A
T
C
C
T
G
A
A
A
AAAA
22100
AAAAAGTGTG CACATATGCA GATACACAGA TCAAACAAAT AGGGCAAAAC
22150
GTGAAACGGT TACTGAACCT AAGTGGTGGG AATGTGAGAG ACCATTGTGC
22200
TCCTCTTCCC GCTGTTCTGT AGGTCAGAAA TTATGCATAA GAAAGGGCTA
22250
GCC
C
T
G
G
G
C
A
C
T
G
G
C
T
C
A
C
A
C
C
T
G
T
A
A
T
C
C
C
A
G
C
A
C
C
T
T
G
G
G
A
G
G
T
C
G
A
G
22300 |
REPEAT
|
var(22269):[T:0.01]
G
T
G
G
G
C
G
G
A
T
C
A
C
T
T
G
A
G
G
T
G
A
G
G
A
G
T
T
C
A
A
G
A
C
C
A
G
C
C
T
G
G
A
C
A
G
C
A
A
G
22350
G
T
G
A
A
A
C
C
G
T
G
T
C
T
C
T
A
C
T
A
A
A
A
A
T
A
C
A
A
A
A
A
T
T
A
G
C
C
A
G
G
C
G
T
G
G
T
A
G
C
22400
A
T
G
C
A
C
C
T
G
T
A
A
T
C
C
C
A
G
C
T
G
C
T
T
G
G
G
A
G
G
C
T
G
A
G
G
C
A
C
G
A
G
A
A
T
T
T
C
T
T
22450
G
A
A
C
C
C
G
G
G
A
G
G
T
G
G
A
G
G
T
T
G
C
A
G
T
G
A
G
C
C
A
A
G
A
T
C
G
C
A
C
C
A
C
T
G
C
A
C
T
C
22500 |
var(22476):[C:0.01]
C
A
G
C
C
T
G
G
G
C
A
G
C
A
G
A
G
C
A
A
G
A
C
T
C
C
A
T
C
T
A
A
A
A
A
A
A
A
A
A
A
A
G
A
A
A
A
A
G
A
22550 |
NOT SCANNED
G
A
A
A
A
A
G
A
A
A
G
A
A
A
A
A
G
A
A
A
T
G
A
G
G
A
G
C
T
G
A
A
T
T
T
T
T
A
A
C
T
T
T
A
T
T
T
T
T
A
22600 |
REPEAT
A
T
T
A
A
C
T
T
C
A
G
T
T
G
A
A
A
C
G
G
C
C
A
C
A
C
C
T
G
G
C
T
G
C
T
G
G
C
T
G
C
C
G
T
A
T
T
G
G
T
22650
C
A
G
T
G
T
G
G
C
C
G
C
C
C
C
A
G
G
A
C
T
C
C
C
C
A
G
G
C
G
C
T
T
T
T
G
G
T
C
A
G
T
G
A
A
G
G
A
A
C
22700
T
G
G
G
T
T
T
C
C
T
C
A
T
C
A
C
C
A
C
G
C
C
T
G
A
C
T
C
C
T
T
G
G
T
G
G
G
G
C
A
G
G
T
G
A
G
G
A
A
G
22750
G
A
A
G
G
T
G
T
G
G
T
C
A
G
A
G
C
C
G
A
C
C
C
A
T
C
A
C
T
G
C
G
C
C
T
C
G
T
C
C
T
T
C
A
C
T
G
C
A
G
22800
A
G
G
T
T
C
T
G
G
G
C
C
C
C
T
C
C
T
T
T
C
A
G
A
G
T
A
G
G
G
G
A
G
G
T
T
G
A
G
G
G
A
A
T
G
A
A
T
G
G
22850
C
T
A
T
G
G
C
A
T
C
C
A
C
A
G
C
T
A
T
G
G
T
C
T
G
A
T
C
T
G
T
G
G
T
C
A
C
G
T
C
T
C
A
C
A
G
C
C
A
T
22900
G
G
A
G
G
C
T
G
G
T
G
T
T
G
A
C
G
T
G
G
T
T
G
G
G
A
A
C
T
G
G
C
A
G
G
G
T
C
T
T
T
C
G
G
C
C
C
A
C
C
22950
C
C
C
A
G
A
A
G
G
G
C
T
G
G
G
C
T
C
C
T
G
C
C
G
C
C
T
G
A
C
G
T
A
G
C
T
T
C
G
G
G
G
G
A
C
G
A
T
C
T
23000
C
A
A
G
T
A
C
C
A
G
G
A
A
A
G
A
C
T
G
G
G
G
A
G
C
A
T
G
C
A
C
T
GGGAGTGT GGAATCGCTC
23050
TACAGAATGG AGGGCT
G
G
C
C
G
G
G
T
G
C
A
G
T
G
G
C
T
T
A
T
G
C
C
T
A
T
A
A
T
T
C
C
A
G
23100 |
REPEAT
C
A
C
T
T
T
G
G
G
A
G
G
C
T
G
A
G
G
C
A
G
G
C
A
G
A
T
C
A
C
T
T
G
A
G
C
C
C
A
G
G
A
G
T
T
T
G
A
G
C
23150
A
A
G
A
T
G
A
G
C
C
T
G
G
C
C
G
A
C
A
T
A
G
T
A
A
G
A
C
C
C
T
G
T
C
G
AATGC AGGGCTGCTG
23200 |
var(23185):[A:0.21]
GGACAGTCGG ACTCAGGCCT GCTGCCGTCC AGCCTGGCAC ATGCCATCAT
23250
GGCGGGCAGT GACGGGCCCC CAGCAGCGTG ATGGCTTCTC TCCCCAG
G
A
G
23300 | Exon 8
E 292
T
A
C
A
T
G
C
G
C
A
T
G
A
T
G
G
G
G
C
T
C
A
G
C
A
G
C
T
G
G
C
T
G
C
A
C
T
G
G
A
G
T
G
C
C
T
G
G
T
T
23350
Y M R M M G L S S W L H W S A W F 309
C
C
T
C
T
T
G
T
T
C
T
T
C
C
T
C
T
T
C
C
T
C
C
T
C
A
T
C
G
C
C
G
C
C
T
C
C
T
T
C
A
T
G
A
C
C
C
T
G
C
23400
L L F F L F L L I A A S F M T L 325
T
C
T
T
C
T
G
T
G
T
C
A
A
G
GTGAGC ATGGCGTCGG TGGGGCTCTG GTGAGGACGG
23450
L F C V K 330
GGAGAGCCAG GGCACCCCAG GAGGGCCCTC TTGGGAAGAA CTTTGTGGTC
23500
AGAGACTTCA GAGAGAGTCT GTCCCTCATG GGGGAGAGGA GCTGTCAATG
23550
TCC
C
ACTCCT CTCGGTGGAG CCGCGTCCCT GTGACCAGGG ATGGTCAGGA
23600 |
var(23554):[A:0.18]
GTCCTCCTGG TCCACCT
C
TG CCGGCCCACC ACGCCCGA
C
T CATGCCTGTG
23650 |
var(23618):[G:0.03]
|
var(23639):[T:0.07]
CCCTGCAG
G
T
G
A
A
G
C
C
A
A
A
T
G
T
A
G
C
C
G
T
G
C
T
G
T
C
C
C
G
C
A
G
C
G
A
C
C
C
C
T
C
C
23700 | Exon 9
V K P N V A V L S R S D P S 344
C
T
G
G
T
G
C
T
C
G
C
C
T
T
C
C
T
G
C
T
G
T
G
C
T
T
C
G
C
C
A
T
C
T
C
T
A
C
C
A
T
C
T
C
C
T
T
C
A
G
23750 |
var(23727):[T:0.07]
L V L A F L L C F A I S T I S F S 361
C
T
T
C
A
T
G
G
T
C
A
G
C
A
C
C
T
T
C
T
T
C
A
G
C
A
A
A
G
G TGAGCCCCAG TCATGGGGCA
23800
F M V S T F F S K 370
GAGTGGGGTT GCCAAGGGGC CAAGGGCCAT CTGCAT
G
GAA ATAACCCA
G
A
23850 |
var(23837):[A:0.01]
|
var(23849):[C:0.01]
GGCTGTGATC GGAAGGGAGA GT
G
GCCTGGT GGAGCTGCCC AGGGAGGAGC
23900 |
var(23873):[A:0.01]
TGACCAGGGG AAGGTTGGAC TGGAAGGAGG AAAGTCAGCG TAATTTAGGG
23950
AGAAGGAGAA TTCAGAGAAG GCAGGTGTGT GGCTGGCCAT GCCGAGTGCT
24000
GTCCAGCAGC CCAAAGGGAA GGCGAGCCAG AAGTGAGGAC AGTGAGCCCG
24050
GCCATGTGCA GAGCCTTGCG GTGACAGTTA CGTTGAAGAT CATTTTTCCT
24100
GTCTGGATTT TGTGTGTCAC TTTGTTATCA TTCTCTTTTG CTTCTTTGTT
24150
TTCCTTTCCT GCCTTCTGTT GGCCTTCTGT AGTGCCTTTT ACCTCGGATG
24200
GTTCAGAGGC TATAAGTTGT GTTTCTCTTT TTTTAGTGAT TACCTTTAAT
24250
GTTTCACTTG ATTACTTACC TCTAAAATTC CAAAAAGTGA AGTTATTCAG
24300
TATGCCCAGG CTC
C
TCCCA
G
G
T
AAAACTCC AACCTCACCA CCACTCTAAG
24350 |
var(24314):[T:0.02]
|
var(24320):[C:0.01]
|
var(24322):[C:0.01]
TACTTTTAGA GGTTCCCAG
T
T
T
T
T
T
G
T
T
T
T
T
T
T
T
T
T
C
G
A
G
C
A
G
T
C
T
T
G
C
T
24400 |
REPEAT
|
NOT SCANNED
C
T
G
T
T
G
C
T
C
A
G
T
C
T
G
G
A
G
T
G
C
A
T
T
A
G
T
G
C
G
A
T
C
T
T
G
G
C
T
C
A
C
T
G
C
A
G
T
C
T
24450
C
T
G
C
C
T
C
T
G
G
G
A
T
T
C
A
A
G
T
G
A
T
T
C
T
T
G
T
G
C
C
T
C
A
G
C
C
T
C
T
T
G
A
G
T
A
G
C
T
G
24500
G
G
A
T
T
A
C
A
G
G
C
G
T
G
T
G
C
C
A
C
C
A
C
G
C
C
T
G
G
C
T
A
A
T
T
T
T
T
T
T
T
T
T
T
T
T
T
T
T
T
24550
T
T
T
T
T
T
T
T
T
T
T
T
T
T
T
T
T
T
T
T
T
G
C
A
T
T
T
T
T
A
G
T
A
G
A
G
A
C
G
G
G
G
T
T
T
T
G
C
C
A
24600
T
G
T
T
G
T
C
C
A
G
G
C
T
G
G
T
C
T
T
G
A
A
A
T
C
C
T
G
A
C
C
T
C
A
A
G
C
G
A
T
C
C
A
T
A
C
T
C
C
T
24650
T
G
G
C
T
T
C
C
C
A
A
A
G
T
G
C
T
G
G
G
A
T
T
A
C
A
G
G
T
G
T
G
A
G
C
C
A
C
T
G
C
G
C
T
T
G
G
C
C
T
24700
T
T
T
T
T
T
T
T
T
T
T
T
C
T
T
T
T
C
T
T
T
T
T
T
T
C
T
T
T
T
C
T
T
T
T
T
T
C
T
T
T
T
T
T
T
T
T
T
T
T
24750 |
REPEAT
T
T
T
G
A
G
A
C
T
G
C
C
T
C
T
T
G
T
T
C
T
G
T
T
G
C
C
C
A
G
G
C
T
G
G
A
G
T
G
C
A
A
T
G
G
C
A
C
A
G
24800
A
C
A
C
G
G
C
T
C
A
C
T
G
C
A
G
C
C
T
T
G
A
A
C
T
G
C
T
G
G
G
C
T
C
A
A
A
G
C
T
A
T
C
T
T
C
C
A
G
C
24850
C
T
C
A
G
C
C
T
T
C
T
G
A
G
T
A
G
C
T
C
A
C
A
C
C
A
C
C
G
T
T
A
C
C
T
G
C
C
A
C
C
A
C
A
C
C
T
A
G
C
24900
T
T
T
T
T
T
T
T
T
T
T
T
T
T
T
T
T
T
T
T
T
C
T
C
A
C
C
A
T
G
T
T
T
C
C
C
A
G
A
C
T
G
G
T
C
T
T
G
A
A
24950
C
T
C
C
T
G
A
T
C
T
C
A
A
G
T
G
A
T
C
C
T
C
C
T
A
C
C
T
C
A
G
C
C
T
C
C
C
A
A
A
G
C
A
T
T
G
G
G
A
T
25000
T
A
C
A
G
G
T
G
T
G
A
G
C
C
A
C
C
A
T
G
C
C
T
G
A
C
C
T
C
C
T
A
A
C
T
T
T
T
G
T
T
G
T
T
G
T
C
T
A
G
25050
T
T
T
G
T
T
T
T
A
T
T
A
T
T
A
A
A
G
A
A
A
A
C
C
T
A
A
G
T
G
A
C
C
A
G
G
C
A
T
G
G
T
A
G
C
T
C
A
C
A
25100 |
REPEAT
C
C
T
G
T
A
A
T
C
C
T
A
G
C
A
C
T
T
T
A
G
G
A
G
G
T
C
A
A
G
G
C
A
G
G
A
G
G
A
T
C
A
C
T
T
G
A
G
C
C
25150
C
A
G
G
A
G
T
T
T
A
A
G
A
C
C
A
G
C
C
T
A
G
G
C
A
A
C
A
T
G
G
C
A
A
G
A
C
C
C
T
G
T
C
T
C
T
A
C
A
A
25200
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
G
T
T
T
A
A
A
A
A
T
T
A
G
C
C
A
G
G
T
G
T
G
G
T
G
G
C
A
25250
T
G
C
C
C
C
T
G
T
G
G
T
C
C
T
A
G
C
T
A
C
T
T
G
G
G
A
G
G
C
T
G
A
G
G
T
G
G
G
A
G
C
A
T
T
G
C
T
T
A
25300
A
G
C
C
C
A
G
G
T
G
G
C
G
G
A
T
G
T
T
G
C
A
G
T
G
A
G
C
T
G
A
G
T
T
T
G
T
A
C
C
A
C
T
G
C
A
T
T
C
C
25350
A
G
C
C
T
G
G
A
G
A
A
C
G
A
G
A
G
G
G
A
C
C
C
T
G
T
C
T
C
A
A
A
A
A
A
A
G
A
A
A
A
A
A
A
A
T
C
A
T
A
25400
A
G
C
A
G
T
T
A
C
T
T
C
C
T
A
T
G
T
G
A
C
A
T
T
C
C
T
G
T
G
C
T
T
T
G
C
C
A
A
C
A
T
A
T
C
T
G
A
T
G
25450
T
G
C
A
C
G
T
G
A
T
T
T
T
C
G
T
G
T
A
C
C
T
G
G
C
T
T
T
T
T
A
G
A
G
T
C
A
C
T
C
T
T
C
T
C
T
G
T
G
T
25500 |
REPEAT
T
G
A
A
G
C
A
C
A
T
C
T
T
T
G
A
G
T
A
G
T
T
C
T
T
C
T
A
G
T
G
G
G
C
A
T
T
G
G
T
A
A
G
T
G
G
T
C
A
G
25550
T
G
C
T
T
T
C
G
A
C
T
T
T
G
T
A
T
G
T
C
C
A
A
A
G
G
T
G
T
C
T
G
T
A
T
T
T
T
G
C
C
C
T
C
A
C
T
C
C
T
25600
G
T
A
T
A
G
T
A
T
T
T
T
A
G
C
T
G
C
C
T
G
T
G
A
A
A
T
T
C
T
C
C
A
C
A
G
A
T
A
G
G
T
G
T
T
C
T
T
C
C
25650
T
T
G
G
C
A
A
T
T
T
T
A
T
A
A
T
G
T
T
A
C
C
T
T
A
T
T
G
C
C
A
T
C
C
G
A
T
A
C
T
C
A
T
C
G
T
T
A
G
T
25700
G
G
G
A
G
T
C
T
G
C
C
A
A
A
A
G
T
C
T
A
G
G
T
G
T
G
A
T
T
T
T
T
C
T
T
T
A
T
G
A
A
C
A
T
T
T
C
G
A
T
25750
C
T
G
A
G
G
G
C
T
C
A
T
G
T
G
T
C
T
T
C
G
G
T
T
C
G
A
A
T
T
T
C
A
A
T
G
A
G
A
T
T
T
C
G
G
G
T
A
A
T
25800
A
T
C
T
C
A
T
C
A
G
A
C
T
T
T
G
C
T
G
T
G
T
G
T
G
T
G
T
G
T
G
T
G
T
G
T
G
T
G
T
G
T
G
T
G
T
G
T
G
T
25850
G
T
G
T
G
T
G
T
A
A
A
A
T
A
C
A
T
A
C
A
A
C
A
A
T
T
T
A
T
G
A
C
C
G
G
G
C
A
C
C
A
T
G
G
C
T
C
A
C
G
25900 |
REPEAT
C
C
T
G
T
A
A
T
C
C
C
A
G
C
A
A
T
T
T
G
G
G
A
G
G
C
C
G
A
G
G
C
G
G
G
T
G
G
A
T
C
A
T
G
A
G
G
T
C
A
25950
G
G
A
G
A
T
T
G
A
G
A
C
C
A
T
C
C
T
G
G
C
C
A
A
C
A
C
A
G
T
G
A
A
A
C
C
T
C
G
T
C
T
C
T
A
C
T
A
A
A
26000
A
A
A
A
A
A
A
A
A
T
A
C
A
A
A
A
A
T
T
A
G
C
C
G
G
G
T
G
T
G
G
T
G
G
C
G
G
G
T
A
C
C
T
G
T
A
G
T
C
C
26050
C
A
G
C
T
A
C
T
C
G
G
G
A
G
G
C
T
G
A
G
G
C
A
G
G
A
G
C
A
T
C
G
C
T
T
G
A
A
C
C
C
A
G
G
A
G
G
C
G
G
26100
A
G
G
T
T
G
C
A
G
T
G
A
G
C
C
G
A
G
G
T
T
G
T
G
C
C
A
G
T
G
C
A
C
T
C
C
A
G
C
C
T
G
G
C
A
A
C
A
G
A
26150
G
C
A
A
G
A
C
T
C
T
G
T
C
T
C
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
G
A
C
C
A
G
G
C
A
C
T
26200 |
REPEAT
A
T
G
G
C
T
C
A
T
G
C
C
T
G
T
A
A
T
C
C
C
A
C
T
T
T
G
G
G
A
G
G
C
C
A
A
G
G
C
T
G
G
C
A
G
A
T
C
A
T
26250
C
T
G
A
G
G
T
C
G
G
G
A
G
T
T
C
G
A
A
A
C
C
A
G
C
C
T
G
A
C
T
A
A
C
A
T
G
G
A
G
A
A
A
C
C
C
T
G
T
C
26300
T
C
T
A
C
T
A
A
A
A
A
T
A
C
A
A
A
A
T
T
A
G
C
C
A
G
G
T
G
T
G
G
T
G
G
C
A
C
A
T
G
C
C
T
G
T
A
A
T
C
26350
C
C
A
G
C
T
T
C
T
T
G
G
G
A
G
G
T
T
G
A
G
G
C
A
G
G
A
G
A
A
T
T
G
C
T
T
G
A
A
C
C
C
A
G
G
A
G
G
C
A
26400
G
A
G
G
T
T
G
C
G
G
T
G
A
G
C
C
G
T
G
A
T
C
A
T
G
C
C
A
C
T
G
C
A
C
T
C
C
A
G
C
C
T
G
G
G
C
A
A
C
A
26450
A
G
A
G
T
G
A
A
A
C
T
T
G
G
T
C
T
C
A
A
A
A
A
A
A
A
A
A
A
A
A
T
T
A
C
C
A
T
T
G
T
G
G
C
C
G
C
T
T
T
26500 |
REPEAT
A
A
G
C
A
T
T
C
A
C
A
T
C
G
T
T
G
T
G
C
A
C
C
C
A
C
C
C
C
C
A
T
G
T
C
C
A
C
C
T
C
C
A
G
A
A
T
G
G
T
26550
T
T
T
C
A
T
G
T
T
T
C
C
C
G
A
C
T
G
A
A
A
C
A
G
T
C
C
C
T
G
T
G
A
A
A
C
A
C
T
G
A
C
T
C
C
C
C
C
A
C
26600
C
C
C
C
C
T
T
C
C
C
T
G
G
A
A
A
C
C
A
G
C
A
C
C
C
T
A
C
T
T
C
C
T
G
T
C
C
C
T
A
T
G
A
G
T
T
T
G
A
T
26650
G
A
C
C
C
T
G
G
G
G
A
C
T
T
C
A
T
G
T
A
A
G
A
G
G
A
A
T
C
G
T
A
C
A
G
T
G
T
T
T
A
T
A
T
G
C
T
G
T
G
26700
C
C
T
G
G
C
T
T
A
T
T
T
C
A
C
T
G
A
G
C
A
T
A
G
C
A
T
C
C
C
C
A
A
G
G
T
T
C
A
T
C
T
G
T
G
T
T
G
T
A
26750
G
C
C
T
G
A
A
T
T
C
C
C
C
T
C
C
T
T
T
T
C
A
A
G
G
C
T
A
G
A
T
G
A
T
A
T
T
C
C
A
T
A
A
T
G
T
A
G
A
T
26800
G
G
G
G
C
C
A
C
A
T
T
T
T
G
T
T
T
A
C
T
T
G
T
T
C
A
T
C
C
A
T
T
G
A
C
A
G
A
C
T
C
T
T
G
G
A
T
G
C
C
26850
C
C
T
G
T
G
T
T
G
T
G
G
C
T
G
T
C
A
T
G
A
G
T
G
T
G
C
T
G
T
G
C
T
G
G
A
C
A
T
G
G
G
T
C
C
C
T
G
C
T
26900
T
T
T
C
A
T
T
C
T
T
T
G
G
G
C
G
T
A
C
A
C
C
C
A
G
A
A
G
T
G
A
A
G
T
T
G
C
T
G
A
A
T
C
C
T
A
T
G
G
C
26950
A
A
T
T
C
C
A
T
G
T
T
T
A
A
C
T
T
T
T
G
A
G
A
G
A
G
A
C
T
G
T
C
A
G
A
C
T
G
T
C
T
T
T
C
C
C
G
C
A
G
27000
T
G
T
C
T
G
C
A
C
C
G
G
T
G
C
G
C
A
T
T
C
C
C
A
C
C
A
G
C
A
G
C
A
C
A
C
A
G
G
T
T
G
C
C
A
G
T
C
T
C
27050
C
T
G
C
A
T
C
C
T
C
G
T
G
A
A
C
A
C
C
T
G
T
T
G
T
T
T
T
C
T
G
A
T
T
G
A
T
T
G
T
T
T
T
T
T
A
T
A
G
T
27100
C
G
C
C
A
T
C
C
T
A
A
T
G
G
G
T
G
T
G
A
G
G
G
G
G
T
A
T
C
T
C
T
C
A
G
T
C
T
T
T
C
A
C
G
T
C
T
G
T
T
27150
A
A
T
T
A
C
T
T
T
T
T
T
T
T
T
T
T
T
T
T
G
A
G
A
T
G
G
A
A
T
C
T
C
G
C
T
C
T
G
T
T
G
C
C
C
A
G
G
C
T
27200 |
REPEAT
A
A
G
T
G
T
A
G
T
G
G
C
A
C
A
A
T
T
G
G
C
T
C
A
C
T
G
C
A
A
C
C
T
C
C
G
C
C
T
T
C
T
G
G
G
T
T
C
A
A
27250
G
T
G
A
T
T
C
T
C
C
T
G
C
C
T
C
A
G
C
C
T
C
C
C
A
A
G
T
A
G
C
T
G
G
G
A
T
T
A
C
A
G
G
C
G
C
C
C
G
C
27300
C
A
C
C
A
T
A
C
C
C
A
G
C
T
A
T
T
T
T
T
G
T
A
G
A
A
A
C
C
G
T
G
T
T
T
T
G
C
C
A
T
G
T
T
G
T
C
C
A
G
27350
G
C
T
G
G
T
C
T
C
A
A
A
C
T
C
C
T
G
A
C
C
T
C
A
A
G
T
G
A
T
C
C
T
C
C
C
A
C
C
T
C
C
G
T
C
T
C
C
C
A
27400
G
A
G
T
G
C
T
G
G
G
A
T
T
A
C
A
G
G
C
A
T
G
A
G
C
C
A
C
C
A
C
G
C
C
T
G
G
C
C
T
C
T
T
A
A
T
T
T
C
T
27450
T
T
T
T
T
T
T
T
T
T
A
A
A
C
T
A
T
A
C
T
T
T
T
A
C
A
A
C
C
C
C
C
T
T
T
C
T
T
C
T
T
T
T
T
T
T
T
T
T
T
27500 |
REPEAT
T
T
T
T
T
T
T
T
T
G
T
G
A
C
A
G
A
G
T
C
T
C
A
C
T
C
T
G
T
T
G
C
C
T
A
G
G
C
T
G
G
A
G
T
G
T
A
G
T
G
27550
G
C
A
C
A
A
T
C
T
T
G
G
C
T
C
A
C
T
G
C
A
A
A
C
T
C
T
G
C
T
G
C
C
T
G
G
G
T
T
C
A
A
G
C
A
A
T
T
C
T
27600
C
C
T
G
C
C
T
C
A
G
C
C
T
C
T
G
A
G
T
A
G
C
T
G
G
C
A
C
T
A
C
A
G
G
T
G
C
A
A
G
C
C
A
G
C
A
T
G
C
C
27650
C
A
G
C
T
A
A
T
T
T
T
G
T
A
T
T
T
T
T
A
G
T
A
G
A
A
A
C
G
G
G
G
T
T
T
C
A
C
C
A
T
G
T
T
G
G
C
C
A
G
27700
G
C
T
G
G
T
C
T
T
G
A
A
C
T
C
C
T
G
A
C
C
T
C
A
G
G
T
G
A
T
C
C
A
C
C
A
G
C
C
T
C
A
G
C
C
T
C
C
C
A
27750
A
A
G
T
G
C
T
G
G
G
A
T
T
A
T
A
G
G
C
G
T
G
A
G
C
T
A
C
C
A
C
A
C
C
T
G
G
C
C
C
C
A